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2014, volume 509, articles 7502

Cancer pp. S49-S49

Herb Brody

Statistics: Attacking an epidemic pp. S50-S51

Mike May

Therapy: This time it's personal pp. S52-S54

Lauren Gravitz

Clinical trials: More trials, fewer tribulations pp. S55-S57

Michael Eisenstein

Nanotechnology: Deliver on a promise pp. S58-S59

Jessica Wright

Comparative biology: Naked ambition pp. S60-S61

Sarah Deweerdt

Prevention: Air of danger pp. S62-S63

Rebecca Kessler

Developing world: Global warning pp. S64-S65

Eric Bender

Bioinformatics: Big data versus the big C pp. S66-S67

Neil Savage

Perspective: Learning to share pp. S68-S68

John Quackenbush

Biology: Three known unknowns pp. S69-S71

Katherine Bourzac

China must continue the momentum of green law pp. 535-535

Hong Yang

Price of knowledge prompts reflection pp. 537-537

Chris Woolston

Old cancer drug gets fresh look pp. 541-542

Heidi Ledford

US Arctic research ship ready to cast off pp. 542-543

Alexandra Witze

Cloud computing beckons scientists pp. 543-544

Nadia Drake

Biomedical institute opens its doors to physicists pp. 544-545

Elizabeth Gibney

Chicken project gets off the ground pp. 546-546

Ewen Callaway

Global health: Deadly dinners pp. 548-551

Meera Subramanian

Theoretical physics: Complexity on the horizon pp. 552-553

Amanda Gefter

Policy: An intergovernmental panel on antimicrobial resistance pp. 555-557

Mark Woolhouse and Jeremy Farrar

Health care: Bring microbial sequencing to hospitals pp. 557-559

Sharon Peacock

Cosmology: Matter and mixology pp. 560-561

Francis Halzen

Books in brief pp. 561-561

Barbara Kiser

Q&A: The space crusader pp. 562-562

Ron Cowen

Stop Madagascar's toad invasion now pp. 563-563

Jonathan E. Kolby

US patient network safeguards data pp. 563-563

Joe V. Selby

Tackle pollution from solar panels pp. 563-563

Hong Yang, Xianjin Huang and Julian R. Thompson

Industries depend on biodiversity too pp. 563-563

Andrew J. Beattie and Paul R. Ehrlich

Douglas Coleman (1931–2014) pp. 564-564

Jeffrey Friedman

A sink down under pp. 566-567

Daniel B. Metcalfe

Barriers to the spread of resistance pp. 567-568

Morten O. A. Sommer

Energy storage wrapped up pp. 568-569

Yury Gogotsi

Female silkworms have the sex factor pp. 570-571

František Marec

The magnetic proton pp. 571-572

V. Alan Kostelecký

Switched at birth pp. 572-573

Katherine E. Yutzey

To affinity and beyond pp. 573-574

David M. Tarlinton

A draft map of the human proteome pp. 575-581

Min-Sik Kim, Sneha M. Pinto, Derese Getnet, Raja Sekhar Nirujogi, Srikanth S. Manda, Raghothama Chaerkady, Anil K. Madugundu, Dhanashree S. Kelkar, Ruth Isserlin, Shobhit Jain, Joji K. Thomas, Babylakshmi Muthusamy, Pamela Leal-Rojas, Praveen Kumar, Nandini A. Sahasrabuddhe, Lavanya Balakrishnan, Jayshree Advani, Bijesh George, Santosh Renuse, Lakshmi Dhevi N. Selvan, Arun H. Patil, Vishalakshi Nanjappa, Aneesha Radhakrishnan, Samarjeet Prasad, Tejaswini Subbannayya, Rajesh Raju, Manish Kumar, Sreelakshmi K. Sreenivasamurthy, Arivusudar Marimuthu, Gajanan J. Sathe, Sandip Chavan, Keshava K. Datta, Yashwanth Subbannayya, Apeksha Sahu, Soujanya D. Yelamanchi, Savita Jayaram, Pavithra Rajagopalan, Jyoti Sharma, Krishna R. Murthy, Nazia Syed, Renu Goel, Aafaque A. Khan, Sartaj Ahmad, Gourav Dey, Keshav Mudgal, Aditi Chatterjee, Tai-Chung Huang, Jun Zhong, Xinyan Wu, Patrick G. Shaw, Donald Freed, Muhammad S. Zahari, Kanchan K. Mukherjee, Subramanian Shankar, Anita Mahadevan, Henry Lam, Christopher J. Mitchell, Susarla Krishna Shankar, Parthasarathy Satishchandra, John T. Schroeder, Ravi Sirdeshmukh, Anirban Maitra, Steven D. Leach, Charles G. Drake, Marc K. Halushka, T. S. Keshava Prasad, Ralph H. Hruban, Candace L. Kerr, Gary D. Bader, Christine A. Iacobuzio-Donahue, Harsha Gowda and Akhilesh Pandey

Mass-spectrometry-based draft of the human proteome pp. 582-587

Mathias Wilhelm, Judith Schlegl, Hannes Hahne, Amin Moghaddas Gholami, Marcus Lieberenz, Mikhail M. Savitski, Emanuel Ziegler, Lars Butzmann, Siegfried Gessulat, Harald Marx, Toby Mathieson, Simone Lemeer, Karsten Schnatbaum, Ulf Reimer, Holger Wenschuh, Martin Mollenhauer, Julia Slotta-Huspenina, Joos-Hendrik Boese, Marcus Bantscheff, Anja Gerstmair, Franz Faerber and Bernhard Kuster

Structural basis of the non-coding RNA RsmZ acting as a protein sponge pp. 588-592

Olivier Duss, Erich Michel, Maxim Yulikov, Mario Schubert, Gunnar Jeschke and Frédéric H.-T. Allain

Three regimes of extrasolar planet radius inferred from host star metallicities pp. 593-595

Lars A. Buchhave, Martin Bizzarro, David W. Latham, Dimitar Sasselov, William D. Cochran, Michael Endl, Howard Isaacson, Diana Juncher and Geoffrey W. Marcy

Direct high-precision measurement of the magnetic moment of the proton pp. 596-599

A. Mooser, S. Ulmer, K. Blaum, K. Franke, H. Kracke, C. Leiteritz, W. Quint, C. C. Rodegheri, C. Smorra and J. Walz

Contribution of semi-arid ecosystems to interannual variability of the global carbon cycle pp. 600-603

Benjamin Poulter, David Frank, Philippe Ciais, Ranga B. Myneni, Niels Andela, Jian Bi, Gregoire Broquet, Josep G. Canadell, Frederic Chevallier, Yi Y. Liu, Steven W. Running, Stephen Sitch and Guido R. van der Werf

Storm-induced sea-ice breakup and the implications for ice extent pp. 604-607

A. L. Kohout, M. J. M. Williams, S. M. Dean and M. H. Meylan

A Palaeozoic shark with osteichthyan-like branchial arches pp. 608-611

Alan Pradel, John G. Maisey, Paul Tafforeau, Royal H. Mapes and Jon Mallatt

Bacterial phylogeny structures soil resistomes across habitats pp. 612-616

Kevin J. Forsberg, Sanket Patel, Molly K. Gibson, Christian L. Lauber, Rob Knight, Noah Fierer and Gautam Dantas

Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors pp. 617-621

Srdjan Maksimovic, Masashi Nakatani, Yoshichika Baba, Aislyn M. Nelson, Kara L. Marshall, Scott A. Wellnitz, Pervez Firozi, Seung-Hyun Woo, Sanjeev Ranade, Ardem Patapoutian and Ellen A. Lumpkin

Piezo2 is required for Merkel-cell mechanotransduction pp. 622-626

Seung-Hyun Woo, Sanjeev Ranade, Andy D. Weyer, Adrienne E. Dubin, Yoshichika Baba, Zhaozhu Qiu, Matt Petrus, Takashi Miyamoto, Kritika Reddy, Ellen A. Lumpkin, Cheryl L. Stucky and Ardem Patapoutian

Scalable control of mounting and attack by Esr1+ neurons in the ventromedial hypothalamus pp. 627-632

Hyosang Lee, Dong-Wook Kim, Ryan Remedios, Todd E. Anthony, Angela Chang, Linda Madisen, Hongkui Zeng and David J. Anderson

A single female-specific piRNA is the primary determiner of sex in the silkworm pp. 633-636

Takashi Kiuchi, Hikaru Koga, Munetaka Kawamoto, Keisuke Shoji, Hiroki Sakai, Yuji Arai, Genki Ishihara, Shinpei Kawaoka, Sumio Sugano, Toru Shimada, Yutaka Suzuki, Masataka G. Suzuki and Susumu Katsuma

Clonal selection in the germinal centre by regulated proliferation and hypermutation pp. 637-640

Alexander D. Gitlin, Ziv Shulman and Michel C. Nussenzweig

Dichloroacetate prevents restenosis in preclinical animal models of vessel injury pp. 641-644

Tobias Deuse, Xiaoqin Hua, Dong Wang, Lars Maegdefessel, Joerg Heeren, Ludger Scheja, Juan P. Bolaños, Aleksandar Rakovic, Joshua M. Spin, Mandy Stubbendorff, Fumiaki Ikeno, Florian Länger, Tanja Zeller, Leonie Schulte-Uentrop, Andrea Stoehr, Ryo Itagaki, Francois Haddad, Thomas Eschenhagen, Stefan Blankenberg, Rainer Kiefmann, Hermann Reichenspurner, Joachim Velden, Christine Klein, Alan Yeung, Robert C. Robbins, Philip S. Tsao and Sonja Schrepfer

An atlas of expression pp. 645-649

Vivien Marx

Medical research: Gene-therapy reboot pp. 651-653

Laura Cassiday

Turning point: Ashvin Vishwanath pp. 653-653

Virginia Gewin

Variations pp. 656-656

William Meikle

2014, volume 509, articles 7501

A Longitude Prize for the twenty-first century pp. 401-401

Martin Rees

Family history wins gene debate pp. 403-403

Regina Nuzzo

Pluto-bound probe faces crisis pp. 407-408

Alexandra Witze

Submersible loss hits research pp. 408-409

Daniel Cressey

Text-mining offers clues to success pp. 410-410

Sara Reardon

Jelly genome mystery pp. 411-411

Ewen Callaway

Activists sound alarm on tiered drug prices pp. 412-412

Erika Check Hayden

Reproductive medicine: The power of three pp. 414-417

Ewen Callaway

Deforestation: Carving up the Amazon pp. 418-419

Barbara Fraser

Mental health: A road map for suicide research and prevention pp. 421-423

André Aleman and Damiaan Denys

Darwin and the women pp. 424-424

Sarah S. Richardson

Forgotten prophet of the Internet pp. 425-425

Philip Ball

Investigate smog to inform policy pp. 427-427

Paul S. Monks

Soil observatory lets researchers dig deep pp. 427-427

Russell Lawley, Bridget A. Emmett and David A. Robinson

Strict vaccine quality control in China pp. 427-427

Zhenglun Liang, Qunying Mao and Junzhi Wang

Rethink Campania's toxic-waste scandal pp. 427-427

Giacomo D'Alisa, Marco Armiero and Salvatore Paolo De Rosa

Internal factors drive Chinese patent surge pp. 427-427

Ching-Yan Wu, Mei-Chih Hu and John A. Mathews

Adolf Seilacher (1925–2014) pp. 428-428

Derek E. G. Briggs

Keeping one's sex pp. 430-431

Douglas L. Chalker

Windy stars that go with a bang pp. 431-432

John J. Eldridge

Double function at the blood–brain barrier pp. 432-433

Christer Betsholtz

Selectivity from flexibility pp. 434-435

Ryotaro Matsuda

Darwinian tumour suppression pp. 435-436

Eduardo Moreno

Fertile fields for seismicity pp. 436-437

Paul Lundgren

The role of senescent cells in ageing pp. 439-446

Jan M. van Deursen

Genome-defence small RNAs exapted for epigenetic mating-type inheritance pp. 447-452

Deepankar Pratap Singh, Baptiste Saudemont, Gérard Guglielmi, Olivier Arnaiz, Jean-François Goût, Malgorzata Prajer, Alexey Potekhin, Ewa Przybòs, Anne Aubusson-Fleury, Simran Bhullar, Khaled Bouhouche, Maoussi Lhuillier-Akakpo, Véronique Tanty, Corinne Blugeon, Adriana Alberti, Karine Labadie, Jean-Marc Aury, Linda Sperling, Sandra Duharcourt and Eric Meyer

Amygdala interneuron subtypes control fear learning through disinhibition pp. 453-458

Steffen B. E. Wolff, Jan Gründemann, Philip Tovote, Sabine Krabbe, Gilad A. Jacobson, Christian Müller, Cyril Herry, Ingrid Ehrlich, Rainer W. Friedrich, Johannes J. Letzkus and Andreas Lüthi

Contrasting forms of cocaine-evoked plasticity control components of relapse pp. 459-464

Vincent Pascoli, Jean Terrier, Julie Espallergues, Emmanuel Valjent, Eoin Cornelius O’Connor and Christian Lüscher

Cell competition is a tumour suppressor mechanism in the thymus pp. 465-470

Vera C. Martins, Katrin Busch, Dilafruz Juraeva, Carmen Blum, Carolin Ludwig, Volker Rasche, Felix Lasitschka, Sergey E. Mastitsky, Benedikt Brors, Thomas Hielscher, Hans Joerg Fehling and Hans-Reimer Rodewald

A Wolf–Rayet-like progenitor of SN 2013cu from spectral observations of a stellar wind pp. 471-474

Avishay Gal-Yam, I. Arcavi, E. O. Ofek, S. Ben-Ami, S. B. Cenko, M. M. Kasliwal, Y. Cao, O. Yaron, D. Tal, J. M. Silverman, A. Horesh, A. De Cia, F. Taddia, J. Sollerman, D. Perley, P. M. Vreeswijk, S. R. Kulkarni, P. E. Nugent, A. V. Filippenko and J. C. Wheeler

Practical quantum key distribution protocol without monitoring signal disturbance pp. 475-478

Toshihiko Sasaki, Yoshihisa Yamamoto and Masato Koashi

Future increases in Arctic precipitation linked to local evaporation and sea-ice retreat pp. 479-482

R. Bintanja and F. M. Selten

Uplift and seismicity driven by groundwater depletion in central California pp. 483-486

Colin B. Amos, Pascal Audet, William C. Hammond, Roland Bürgmann, Ingrid A. Johanson and Geoffrey Blewitt

High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells pp. 487-491

Yuexin Zhou, Shiyou Zhu, Changzu Cai, Pengfei Yuan, Chunmei Li, Yanyi Huang and Wensheng Wei

Copper is required for oncogenic BRAF signalling and tumorigenesis pp. 492-496

Donita C. Brady, Matthew S. Crowe, Michelle L. Turski, G. Aaron Hobbs, Xiaojie Yao, Apirat Chaikuad, Stefan Knapp, Kunhong Xiao, Sharon L. Campbell, Dennis J. Thiele and Christopher M. Counter

Protective mucosal immunity mediated by epithelial CD1d and IL-10 pp. 497-502

Torsten Olszak, Joana F. Neves, C. Marie Dowds, Kristi Baker, Jonathan Glickman, Nicholas O. Davidson, Chyuan-Sheng Lin, Christian Jobin, Stephan Brand, Karl Sotlar, Koichiro Wada, Kazufumi Katayama, Atsushi Nakajima, Hiroyuki Mizuguchi, Kunito Kawasaki, Kazuhiro Nagata, Werner Müller, Scott B. Snapper, Stefan Schreiber, Arthur Kaser, Sebastian Zeissig and Richard S. Blumberg

Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid pp. 503-506

Long N. Nguyen, Dongliang Ma, Guanghou Shui, Peiyan Wong, Amaury Cazenave-Gassiot, Xiaodong Zhang, Markus R. Wenk, Eyleen L. K. Goh and David L. Silver

Mfsd2a is critical for the formation and function of the blood–brain barrier pp. 507-511

Ayal Ben-Zvi, Baptiste Lacoste, Esther Kur, Benjamin J. Andreone, Yoav Mayshar, Han Yan and Chenghua Gu

Structure of the AcrAB–TolC multidrug efflux pump pp. 512-515

Dijun Du, Zhao Wang, Nathan R. James, Jarrod E. Voss, Ewa Klimont, Thelma Ohene-Agyei, Henrietta Venter, Wah Chiu and Ben F. Luisi

Structural basis of Sec-independent membrane protein insertion by YidC pp. 516-520

Kaoru Kumazaki, Shinobu Chiba, Mizuki Takemoto, Arata Furukawa, Ken-ichi Nishiyama, Yasunori Sugano, Takaharu Mori, Naoshi Dohmae, Kunio Hirata, Yoshiko Nakada-Nakura, Andrés D. Maturana, Yoshiki Tanaka, Hiroyuki Mori, Yuji Sugita, Fumio Arisaka, Koreaki Ito, Ryuichiro Ishitani, Tomoya Tsukazaki and Osamu Nureki

Technology: Building opportunities pp. 521-523

Neil Savage

Trials pp. 526-526

John Frizell

2014, volume 509, articles 7500

Is it right to reverse extinction? pp. 261-261

Ben Minteer

Maths reality check resonates online pp. 263-263

Chris Woolston

Call for better oversight of nuclear-waste storage pp. 267-268

Declan Butler

Microbiome therapy gains market traction pp. 269-270

Sara Reardon

Atlantic current strength declines pp. 270-271

Quirin Schiermeier

NASA plans Mars sample-return rover pp. 272-272

Alexandra Witze

Homophobia and HIV research: Under siege pp. 274-275

Linda Nordling

Cosmology: First light pp. 276-278

Joanne Baker

Climate science: Understand Arctic methane variability pp. 279-281

Torben R. Christensen

Policy: NIH to balance sex in cell and animal studies pp. 282-283

Janine A. Clayton and Francis S. Collins

Sociobiology: The distributed brain pp. 284-285

Herbert Gintis

Books in brief pp. 285-285

Barbara Kiser

Chemistry: Intoxicating science pp. 286-286

Jamie Goode

Development: Dammed dreams pp. 287-287

Monya Baker

Tamiflu reviewers respond to critics pp. 288-288

Peter Doshi and Tom Jefferson

Prion identity wrongly credited pp. 288-288

R. John Ellis

Call for UN to act on food security pp. 288-288

Bruce Campbell

Ocean pollution foils search for plane pp. 288-288

Keith Alverson

Shifting storms pp. 290-291

Hamish Ramsay

New letters for life's alphabet pp. 291-292

Ross Thyer and Jared Ellefson

Collaborative synthesis pp. 293-294

John L. Wood

To care or not to care pp. 294-295

Ivan Rodriguez

Radio waves zap the biomagnetic compass pp. 296-297

Joseph L. Kirschvink

Geology and climate drive diversification pp. 297-298

Rosemary G. Gillespie and George K. Roderick

Recent advances in homogeneous nickel catalysis pp. 299-309

Sarah Z. Tasker, Eric A. Standley and Timothy F. Jamison

Nucleotide signalling during inflammation pp. 310-317

Marco Idzko, Davide Ferrari and Holger K. Eltzschig

Total synthesis and isolation of citrinalin and cyclopiamine congeners pp. 318-324

Eduardo V. Mercado-Marin, Pablo Garcia-Reynaga, Stelamar Romminger, Eli. F. Pimenta, David K. Romney, Michael W. Lodewyk, David E. Williams, Raymond J. Andersen, Scott J. Miller, Dean J. Tantillo, Roberto G. S. Berlinck and Richmond Sarpong

Galanin neurons in the medial preoptic area govern parental behaviour pp. 325-330

Zheng Wu, Anita E. Autry, Joseph F. Bergan, Mitsuko Watabe-Uchida and Catherine G. Dulac

Space–time wiring specificity supports direction selectivity in the retina pp. 331-336

Jinseop S. Kim, Matthew J. Greene, Aleksandar Zlateski, Kisuk Lee, Mark Richardson, Srinivas C. Turaga, Michael Purcaro, Matthew Balkam, Amy Robinson, Bardia F. Behabadi, Michael Campos, Winfried Denk and H. Sebastian Seung

c-kit+ cells minimally contribute cardiomyocytes to the heart pp. 337-341

Jop H. van Berlo, Onur Kanisicak, Marjorie Maillet, Ronald J. Vagnozzi, Jason Karch, Suh-Chin J. Lin, Ryan C. Middleton, Eduardo Marbán and Jeffery D. Molkentin

Cepheid variables in the flared outer disk of our galaxy pp. 342-344

Michael W. Feast, John W. Menzies, Noriyuki Matsunaga and Patricia A. Whitelock

Tracking excited-state charge and spin dynamics in iron coordination complexes pp. 345-348

Wenkai Zhang, Roberto Alonso-Mori, Uwe Bergmann, Christian Bressler, Matthieu Chollet, Andreas Galler, Wojciech Gawelda, Ryan G. Hadt, Robert W. Hartsock, Thomas Kroll, Kasper S. Kjær, Katharina Kubiček, Henrik T. Lemke, Huiyang W. Liang, Drew A. Meyer, Martin M. Nielsen, Carola Purser, Joseph S. Robinson, Edward I. Solomon, Zheng Sun, Dimosthenis Sokaras, Tim B. van Driel, György Vankó, Tsu-Chien Weng, Diling Zhu and Kelly J. Gaffney

The poleward migration of the location of tropical cyclone maximum intensity pp. 349-352

James P. Kossin, Kerry A. Emanuel and Gabriel A. Vecchi

Anthropogenic electromagnetic noise disrupts magnetic compass orientation in a migratory bird pp. 353-356

Svenja Engels, Nils-Lasse Schneider, Nele Lefeldt, Christine Maira Hein, Manuela Zapka, Andreas Michalik, Dana Elbers, Achim Kittel, P. J. Hore and Henrik Mouritsen

Dynamics and associations of microbial community types across the human body pp. 357-360

Tao Ding and Patrick D. Schloss

T-cell activation by transitory neo-antigens derived from distinct microbial pathways pp. 361-365

Alexandra J. Corbett, Sidonia B. G. Eckle, Richard W. Birkinshaw, Ligong Liu, Onisha Patel, Jennifer Mahony, Zhenjun Chen, Rangsima Reantragoon, Bronwyn Meehan, Hanwei Cao, Nicholas A. Williamson, Richard A. Strugnell, Douwe Van Sinderen, Jeffrey Y. W. Mak, David P. Fairlie, Lars Kjer-Nielsen, Jamie Rossjohn and James McCluskey

Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases pp. 366-370

Etienne Meunier, Mathias S. Dick, Roland F. Dreier, Nura Schürmann, Daniela Kenzelmann Broz, Søren Warming, Merone Roose-Girma, Dirk Bumann, Nobuhiko Kayagaki, Kiyoshi Takeda, Masahiro Yamamoto and Petr Broz

Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq pp. 371-375

Barbara Treutlein, Doug G. Brownfield, Angela R. Wu, Norma F. Neff, Gary L. Mantalas, F. Hernan Espinoza, Tushar J. Desai, Mark A. Krasnow and Stephen R. Quake

Disruption of Mediator rescues the stunted growth of a lignin-deficient Arabidopsis mutant pp. 376-380

Nicholas D. Bonawitz, Jeong Im Kim, Yuki Tobimatsu, Peter N. Ciesielski, Nickolas A. Anderson, Eduardo Ximenes, Junko Maeda, John Ralph, Bryon S. Donohoe, Michael Ladisch and Clint Chapple

Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2 pp. 381-384

Abdul Ghafoor Khan, Jillian Whidby, Matthew T. Miller, Hannah Scarborough, Alexandra V. Zatorski, Alicja Cygan, Aryn A. Price, Samantha A. Yost, Caitlin D. Bohannon, Joshy Jacob, Arash Grakoui and Joseph Marcotrigiano

A semi-synthetic organism with an expanded genetic alphabet pp. 385-388

Denis A. Malyshev, Kirandeep Dhami, Thomas Lavergne, Tingjian Chen, Nan Dai, Jeremy M. Foster, Ivan R. Corrêa and Floyd E. Romesberg

Career gaps: Maternity muddle pp. 389-391

Amanda Mascarelli

Turning point: Collin Diedrich pp. 391-391

Virginia Gewin

Thanks for the memory pp. 394-394

Milo James Fowler

2014, volume 509, articles 7499

Time to settle the synthetic controversy pp. 135-135

Volker ter Meulen

Antibiotic resistance sweeping developing world pp. 141-142

Sara Reardon

Avalanche hotspot revealed pp. 142-143

Jane Qiu

Indian elections fall flat on science pp. 145-145

Sanjay Kumar

Universities seek to boost industry partnerships pp. 146-146

Erika Check Hayden

Imaging: Cancer caught in the act pp. 148-149

Corie Lok

Synthetic biology: Cultural divide pp. 152-154

Bryn Nelson

Society: Realizing China's urban dream pp. 158-160

Xuemei Bai, Peijun Shi and Yansui Liu

Life in flux pp. 161-162

Renee Reijo Pera

Q&A: Canopy composer pp. 162-163

Jascha Hoffman

Books in brief pp. 163-163

Barbara Kiser

India: Shed the bad science image pp. 164-164

Shobhana Narasimhan

India: Research split harmed universities pp. 164-164

Biswa Prasun Chatterji

India: Overhaul university teaching pp. 164-164

Dhruba J. Saikia and Rowena Robinson

Aim for balance in Ukraine reports pp. 164-164

Andrew Isaac Meso

Help poster sessions to grab attention pp. 164-164

Nicholas Rowe

Engineering explored pp. 166-167

Pamela A. Silver, Jeffrey C. Way, Frances H. Arnold and Joseph T. Meyerowitz

The origin of regional Arctic warming pp. 167-168

Jürgen Bader

Construction of a yeast chromosome pp. 168-169

Daniel G. Gibson and J. Craig Venter

A virtual Universe pp. 170-171

Michael Boylan-Kolchin

Supply and demand pp. 171-172

Arne O. Mooers

Diversity in the afterlife pp. 173-174

Jennie R. McLaren

Action at a distance in a light receptor pp. 174-175

Anna W. Baker and Katrina T. Forest

Properties of galaxies reproduced by a hydrodynamic simulation pp. 177-182

M. Vogelsberger, S. Genel, V. Springel, P. Torrey, D. Sijacki, D. Xu, G. Snyder, S. Bird, D. Nelson and L. Hernquist

FXR is a molecular target for the effects of vertical sleeve gastrectomy pp. 183-188

Karen K. Ryan, Valentina Tremaroli, Christoffer Clemmensen, Petia Kovatcheva-Datchary, Andriy Myronovych, Rebekah Karns, Hilary E. Wilson-Pérez, Darleen A. Sandoval, Rohit Kohli, Fredrik Bäckhed and Randy J. Seeley

Astrocyte-encoded positional cues maintain sensorimotor circuit integrity pp. 189-194

Anna V. Molofsky, Kevin W. Kelley, Hui-Hsin Tsai, Stephanie A. Redmond, Sandra M. Chang, Lohith Madireddy, Jonah R. Chan, Sergio E. Baranzini, Erik M. Ullian and David H. Rowitch

Synapse elimination and learning rules co-regulated by MHC class I H2-Db pp. 195-200

Hanmi Lee, Barbara K. Brott, Lowry A. Kirkby, Jaimie D. Adelson, Sarah Cheng, Marla B. Feller, Akash Datwani and Carla J. Shatz

Circular polarization in the optical afterglow of GRB 121024A pp. 201-204

K. Wiersema, S. Covino, K. Toma, A. J. van der Horst, K. Varela, M. Min, J. Greiner, R. L. C. Starling, N. R. Tanvir, R. A. M. J. Wijers, S. Campana, P. A. Curran, Y. Fan, J. P. U. Fynbo, J. Gorosabel, A. Gomboc, D. Götz, J. Hjorth, Z. P. Jin, S. Kobayashi, C. Kouveliotou, C. Mundell, P. T. O’Brien, E. Pian, A. Rowlinson, D. M. Russell, R. Salvaterra, S. di Serego Alighieri, G. Tagliaferri, S. D. Vergani, J. Elliott, C. Fariña, O. E. Hartoog, R. Karjalainen, S. Klose, F. Knust, A. J. Levan, P. Schady, V. Sudilovsky and R. Willingale

Classical shear cracks drive the onset of dry frictional motion pp. 205-208

Ilya Svetlizky and Jay Fineberg

Tropical forcing of the recent rapid Arctic warming in northeastern Canada and Greenland pp. 209-212

Qinghua Ding, John M. Wallace, David S. Battisti, Eric J. Steig, Ailie J. E. Gallant, Hyung-Jin Kim and Lei Geng

Predicting biodiversity change and averting collapse in agricultural landscapes pp. 213-217

Chase D. Mendenhall, Daniel S. Karp, Christoph F. J. Meyer, Elizabeth A. Hadly and Gretchen C. Daily

Consequences of biodiversity loss for litter decomposition across biomes pp. 218-221

I. Tanya Handa, Rien Aerts, Frank Berendse, Matty P. Berg, Andreas Bruder, Olaf Butenschoen, Eric Chauvet, Mark O. Gessner, Jérémy Jabiol, Marika Makkonen, Brendan G. McKie, Björn Malmqvist, Edwin T. H. M. Peeters, Stefan Scheu, Bernhard Schmid, Jasper van Ruijven, Veronique C. A. Vos and Stephan Hättenschwiler

Niche filling slows the diversification of Himalayan songbirds pp. 222-225

Trevor D. Price, Daniel M. Hooper, Caitlyn D. Buchanan, Ulf S. Johansson, D. Thomas Tietze, Per Alström, Urban Olsson, Mousumi Ghosh-Harihar, Farah Ishtiaq, Sandeep K. Gupta, Jochen Martens, Bettina Harr, Pratap Singh and Dhananjai Mohan

Sensory stimulation shifts visual cortex from synchronous to asynchronous states pp. 226-229

Andrew Y. Y. Tan, Yuzhi Chen, Benjamin Scholl, Eyal Seidemann and Nicholas J. Priebe

Listeria monocytogenes exploits efferocytosis to promote cell-to-cell spread pp. 230-234

Mark A. Czuczman, Ramzi Fattouh, Jorik M. van Rijn, Veronica Canadien, Suzanne Osborne, Aleixo M. Muise, Vijay K. Kuchroo, Darren E. Higgins and John H. Brumell

NRROS negatively regulates reactive oxygen species during host defence and autoimmunity pp. 235-239

Rajkumar Noubade, Kit Wong, Naruhisa Ota, Sascha Rutz, Celine Eidenschenk, Patricia A. Valdez, Jiabing Ding, Ivan Peng, Andrew Sebrell, Patrick Caplazi, Jason DeVoss, Robert H. Soriano, Tao Sai, Rongze Lu, Zora Modrusan, Jason Hackney and Wenjun Ouyang

Endosomes are specialized platforms for bacterial sensing and NOD2 signalling pp. 240-244

Norihiro Nakamura, Jennie R. Lill, Qui Phung, Zhaoshi Jiang, Corey Bakalarski, Ann de Mazière, Judith Klumperman, Megan Schlatter, Lélia Delamarre and Ira Mellman

Signal amplification and transduction in phytochrome photosensors pp. 245-248

Heikki Takala, Alexander Björling, Oskar Berntsson, Heli Lehtivuori, Stephan Niebling, Maria Hoernke, Irina Kosheleva, Robert Henning, Andreas Menzel, Janne A. Ihalainen and Sebastian Westenhoff

Continuing education: Study broad and deep pp. 249-250

Sarah Webb

Turning point: Marta Zlatic pp. 251-251

Virginia Gewin

Killstealer pp. 254-254

Alter S. Reiss

2014, volume 509, articles 7498

Antibiotics pp. S1-S1

Mike May

Antibiotic resistance: An infectious arms race pp. S2-S3

Karyn Hede

Drug development: Time for teamwork pp. S4-S5

Mike May

Microbiology: Resistance fighters pp. S6-S8

Bill Cannon

The moral problem with commercial seal hunting pp. 9-9

Andy Butterworth

Perspective: The age of the phage pp. S9-S9

Shigenobu Matsuzaki, Jumpei Uchiyama, Iyo Takemura-Uchiyama and Masanori Daibata

Drug discovery: Leaving no stone unturned pp. S10-S12

Katharine Gammon

Perspective: Synthetic biology revives antibiotics pp. S13-S13

Gerard Wright

Diagnostics: Detection drives defence pp. S14-S15

Rebecca Kanthor

Doubts over heart stem-cell therapy pp. 15-16

Alison Abbott

US biodefence facilities ramp up pp. 16-17

Sara Reardon

Public health: The politics of antibiotics pp. S16-S17

Megan Cully

Basic science finds corporate refuge pp. 18-19

Nadia Drake

Two plants to put ‘clean coal’ to test pp. 20-20

Richard Van Noorden

Infectious diseases: Smallpox watch pp. 22-24

Sara Reardon

Agriculture: Engage farmers in research pp. 25-27

Tom MacMillan and Tim G. Benton

Policy: Regulate embryos made for research pp. 27-28

Insoo Hyun

Science biography: A voyage round Newton pp. 30-31

Mordechai Feingold

Books in brief pp. 31-31

Barbara Kiser

Space policy: A clearer final frontier pp. 32-32

David Southwood

Rise in retractions is a signal of integrity pp. 33-33

Daniele Fanelli

Practical costs of data sharing pp. 33-33

Geoffrey J. Goodhill

Scottish separation could harm science pp. 33-33

Hugh Pennington, Susan A. Shaw and Andrew Miller

Former Iron Curtain safeguards wildlife pp. 33-33

Bernhard Jank and Johannes Rath

Two brains and a forgotten theory pp. 33-33

Kevin S. Weiner

Drought in the Congo Basin pp. 36-37

Jeffrey Q. Chambers and Dar A. Roberts

Bright electron twisters pp. 37-38

Jun Yuan

Feedback throttled down for smooth moves pp. 38-39

Stephen H. Scott and Frédéric Crevecoeur

Making the Earth move pp. 40-41

Rob L. Evans

A new spin on exoplanets pp. 41-42

Travis Barman

Presynaptic inhibition of spinal sensory feedback ensures smooth movement pp. 43-48

Andrew J. P. Fink, Katherine R. Croce, Z. Josh Huang, L. F. Abbott, Thomas M. Jessell and Eiman Azim

Haematopoietic stem cells require a highly regulated protein synthesis rate pp. 49-54

Robert A. J. Signer, Jeffrey A. Magee, Adrian Salic and Sean J. Morrison

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies pp. 55-62

Nicole A. Doria-Rose, Chaim A. Schramm, Jason Gorman, Penny L. Moore, Jinal N. Bhiman, Brandon J. DeKosky, Michael J. Ernandes, Ivelin S. Georgiev, Helen J. Kim, Marie Pancera, Ryan P. Staupe, Han R. Altae-Tran, Robert T. Bailer, Ema T. Crooks, Albert Cupo, Aliaksandr Druz, Nigel J. Garrett, Kam H. Hoi, Rui Kong, Mark K. Louder, Nancy S. Longo, Krisha McKee, Molati Nonyane, Sijy O’Dell, Ryan S. Roark, Rebecca S. Rudicell, Stephen D. Schmidt, Daniel J. Sheward, Cinque Soto, Constantinos Kurt Wibmer, Yongping Yang, Zhenhai Zhang, James C. Mullikin, James M. Binley, Rogier W. Sanders, Ian A. Wilson, John P. Moore, Andrew B. Ward, George Georgiou, Carolyn Williamson, Salim S. Abdool Karim, Lynn Morris, Peter D. Kwong, Lawrence Shapiro and John R. Mascola

Fast spin of the young extrasolar planet β Pictoris b pp. 63-65

Ignas A. G. Snellen, Bernhard R. Brandl, Remco J. de Kok, Matteo Brogi, Jayne Birkby and Henriette Schwarz

Molecular photons interfaced with alkali atoms pp. 66-70

Petr Siyushev, Guilherme Stein, Jörg Wrachtrup and Ilja Gerhardt

Spontaneous transfer of chirality in an atropisomerically enriched two-axis system pp. 71-75

Kimberly T. Barrett, Anthony J. Metrano, Paul R. Rablen and Scott J. Miller

North Atlantic forcing of tropical Indian Ocean climate pp. 76-80

Mahyar Mohtadi, Matthias Prange, Delia W. Oppo, Ricardo De Pol-Holz, Ute Merkel, Xiao Zhang, Stephan Steinke and Andreas Lückge

Electrical conductivity during incipient melting in the oceanic low-velocity zone pp. 81-85

David Sifré, Emmanuel Gardés, Malcolm Massuyeau, Leila Hashim, Saswata Hier-Majumder and Fabrice Gaillard

Widespread decline of Congo rainforest greenness in the past decade pp. 86-90

Liming Zhou, Yuhong Tian, Ranga B. Myneni, Philippe Ciais, Sassan Saatchi, Yi Y. Liu, Shilong Piao, Haishan Chen, Eric F. Vermote, Conghe Song and Taehee Hwang

Identification of genomic alterations in oesophageal squamous cell cancer pp. 91-95

Yongmei Song, Lin Li, Yunwei Ou, Zhibo Gao, Enmin Li, Xiangchun Li, Weimin Zhang, Jiaqian Wang, Liyan Xu, Yong Zhou, Xiaojuan Ma, Lingyan Liu, Zitong Zhao, Xuanlin Huang, Jing Fan, Lijia Dong, Gang Chen, Liying Ma, Jie Yang, Longyun Chen, Minghui He, Miao Li, Xuehan Zhuang, Kai Huang, Kunlong Qiu, Guangliang Yin, Guangwu Guo, Qiang Feng, Peishan Chen, Zhiyong Wu, Jianyi Wu, Ling Ma, Jinyang Zhao, Longhai Luo, Ming Fu, Bainan Xu, Bo Chen, Yingrui Li, Tong Tong, Mingrong Wang, Zhihua Liu, Dongxin Lin, Xiuqing Zhang, Huanming Yang, Jun Wang and Qimin Zhan

Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington’s disease pp. 96-100

Bindu D. Paul, Juan I. Sbodio, Risheng Xu, M. Scott Vandiver, Jiyoung Y. Cha, Adele M. Snowman and Solomon H. Snyder

Nuclear reprogramming by interphase cytoplasm of two-cell mouse embryos pp. 101-104

Eunju Kang, Guangming Wu, Hong Ma, Ying Li, Rebecca Tippner-Hedges, Masahito Tachibana, Michelle Sparman, Don P. Wolf, Hans R. Schöler and Shoukhrat Mitalipov

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy pp. 105-109

Joseph D. Mancias, Xiaoxu Wang, Steven P. Gygi, J. Wade Harper and Alec C. Kimmelman

Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I pp. 110-114

Alys Peisley, Bin Wu, Hui Xu, Zhijian J. Chen and Sun Hur

Structure of the human P2Y12 receptor in complex with an antithrombotic drug pp. 115-118

Kaihua Zhang, Jin Zhang, Zhan-Guo Gao, Dandan Zhang, Lan Zhu, Gye Won Han, Steven M. Moss, Silvia Paoletta, Evgeny Kiselev, Weizhen Lu, Gustavo Fenalti, Wenru Zhang, Christa E. Müller, Huaiyu Yang, Hualiang Jiang, Vadim Cherezov, Vsevolod Katritch, Kenneth A. Jacobson, Raymond C. Stevens, Beili Wu and Qiang Zhao

Agonist-bound structure of the human P2Y12 receptor pp. 119-122

Jin Zhang, Kaihua Zhang, Zhan-Guo Gao, Silvia Paoletta, Dandan Zhang, Gye Won Han, Tingting Li, Limin Ma, Wenru Zhang, Christa E. Müller, Huaiyu Yang, Hualiang Jiang, Vadim Cherezov, Vsevolod Katritch, Kenneth A. Jacobson, Raymond C. Stevens, Beili Wu and Qiang Zhao

Public relations: For your information pp. 123-125

Chris Woolston

Choosing to stay pp. 125-125

Yoshimi Rii

An uncanny life pp. 128-128

Ryan Rubai