Bidirectional electromagnetic control of the hypothalamus regulates feeding and metabolism

Sarah A. Stanley, Leah Kelly, Kaamashri N. Latcha, Sarah F. Schmidt, Xiaofei Yu, Alexander R. Nectow, Jeremy Sauer, Jonathan P. Dyke, Jonathan S. Dordick and Jeffrey M. Friedman ()
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Sarah A. Stanley: Laboratory of Molecular Genetics, Rockefeller University
Leah Kelly: Laboratory of Molecular Genetics, Rockefeller University
Kaamashri N. Latcha: Laboratory of Molecular Genetics, Rockefeller University
Sarah F. Schmidt: Laboratory of Molecular Genetics, Rockefeller University
Xiaofei Yu: Laboratory of Molecular Genetics, Rockefeller University
Alexander R. Nectow: Laboratory of Molecular Genetics, Rockefeller University
Jeremy Sauer: Center for Biotechnology & Interdisciplinary Studies, Rensselaer Polytechnic Institute
Jonathan P. Dyke: Weill Cornell Medical College
Jonathan S. Dordick: Center for Biotechnology & Interdisciplinary Studies, Rensselaer Polytechnic Institute
Jeffrey M. Friedman: Laboratory of Molecular Genetics, Rockefeller University

Nature, 2016, vol. 531, issue 7596, 647-650

Abstract: Activation of glucose-sensing neurons in the ventromedial hypothalamic nucleus using radio waves or magnetic fields remotely and non-invasively in vivo increases plasma glucose and glucagon, and suppresses plasma insulin; conversely, remote inhibition of glucose-sensing neurons decreased blood glucose and increased plasma insulin.

Date: 2016
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DOI: 10.1038/nature17183

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