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Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases

Dominik A. Herbst, Roman P. Jakob, Franziska Zähringer and Timm Maier ()
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Dominik A. Herbst: University of Basel
Roman P. Jakob: University of Basel
Franziska Zähringer: University of Basel
Timm Maier: University of Basel

Nature, 2016, vol. 531, issue 7595, 533-537

Abstract: A hybrid crystal structure of Mycobacterium smegmatis mycocerosic acid synthase, a multienzyme involved in the biosynthesis of mycobacterial branched-chain fatty acids, exemplifies the organization of fully-reducing polyketide synthases.

Date: 2016
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DOI: 10.1038/nature16993

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