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Crystal structure of eukaryotic translation initiation factor 2B

Kazuhiro Kashiwagi, Mari Takahashi, Madoka Nishimoto, Takuya B. Hiyama, Toshiaki Higo, Takashi Umehara, Kensaku Sakamoto, Takuhiro Ito () and Shigeyuki Yokoyama ()
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Kazuhiro Kashiwagi: Graduate School of Science, The University of Tokyo, Bunkyo-ku
Mari Takahashi: RIKEN Center for Life Science Technologies
Madoka Nishimoto: RIKEN Center for Life Science Technologies
Takuya B. Hiyama: Graduate School of Science, The University of Tokyo, Bunkyo-ku
Toshiaki Higo: RIKEN Systems and Structural Biology Center
Takashi Umehara: RIKEN Systems and Structural Biology Center
Kensaku Sakamoto: RIKEN Systems and Structural Biology Center
Takuhiro Ito: Graduate School of Science, The University of Tokyo, Bunkyo-ku
Shigeyuki Yokoyama: Graduate School of Science, The University of Tokyo, Bunkyo-ku

Nature, 2016, vol. 531, issue 7592, 122-125

Abstract: The crystal structure of Schizosaccharomyces pombe guanine nucleotide exchange factor eIF2B, providing a structural framework for the eIF2B-mediated mechanism of stress-induced translational control.

Date: 2016
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DOI: 10.1038/nature16991

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