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2019, volume 569, articles 7758

Publisher Correction: p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis pp. E10-E10

Le Li, Youxiang Mao, Lina Zhao, Lijia Li, Jinjun Wu, Mengjia Zhao, Wenjing Du, Li Yu and Peng Jiang

Publisher Correction: Resonant electro-optic frequency comb pp. E11-E11

Alfredo Rueda, Florian Sedlmeir, Madhuri Kumari, Gerd Leuchs and Harald G. L. Schwefel

Publisher Correction: Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS–STING signalling pp. E12-E12

James B. Eaglesham, Youdong Pan, Thomas S. Kupper and Philip J. Kranzusch

AI researchers in China want to keep the global-sharing culture alive pp. S33-S35

Sarah O’Meara

The biotechnologists making their mark on the international stage pp. S37-S39

Bianca Nogrady

Lessons from cold fusion, 30 years on pp. 601-601

Philip Ball

World’s largest laser lab rocked by slew of disputes pp. 607-608

Alison Abbott

Brazilian scientists strive to turn politicians into allies pp. 609-609

Rodrigo de Oliveira Andrade

These scientists are setting a forest on fire — and studying it with drones pp. 610-610

Alexandra Witze

Google revives controversial cold-fusion experiments pp. 611-611

Elizabeth Gibney

Genomics institute to close world-leading animal facility pp. 612-612

Holly Else

Can tracking people through phone-call data improve lives? pp. 614-617

Amy Maxmen

Hacking conservation: how a tech start-up aims to save biodiversity pp. 618-619

Lisa Palmer

Rethinking impact factors: better ways to judge a journal pp. 621-623

Paul Wouters, Cassidy R. Sugimoto, Vincent Larivière, Marie E. McVeigh, Bernd Pulverer, Sarah de Rijcke and Ludo Waltman

Priorities for the next 10 years of human microbiome research pp. 623-625

Lita Proctor

The neurobiology of conscience pp. 627-628

Nicholas A. Christakis

Of chaos, storms and forking paths: the principles of uncertainty pp. 628-629

Andrew Gelman

World of addiction, zen cosmology, and the impending aquacalypse: Books in brief pp. 629-629

Barbara Kiser

Use nudges to change behaviour towards conservation pp. 630-630

Brendan Fisher, Theresa Marteau and Andrew Balmford

Would a gene-editing ban fit human-rights law? pp. 630-630

Andrea Boggio

Regrow forests with locals’ participation pp. 630-630

Rose Pritchard and Dan Brockington

Satellite time series can guide forest restoration pp. 630-630

Joanne C. White, Michael A. Wulder, Txomin Hermosilla and Nicholas C. Coops

Tracking humans and microbes pp. 632-633

Verónica Lloréns-Rico and Jeroen Raes

Quantum simulation of black-hole radiation pp. 634-635

Silke Weinfurtner

Guarding the gate for mitochondrial entry pp. 635-637

Sylvie Callegari and Peter Rehling

Nerve cells from the brain invade prostate tumours pp. 637-638

Simon T. Schafer and Fred H. Gage

Bridging the gap between artificial vision and touch pp. 638-639

Giulia Pasquale

Asia’s shrinking glaciers protect large populations from drought stress pp. 649-654

Hamish D. Pritchard

Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases pp. 655-662

Jason Lloyd-Price, Cesar Arze, Ashwin N. Ananthakrishnan, Melanie Schirmer, Julian Avila-Pacheco, Tiffany W. Poon, Elizabeth Andrews, Nadim J. Ajami, Kevin S. Bonham, Colin J. Brislawn, David Casero, Holly Courtney, Antonio Gonzalez, Thomas G. Graeber, A. Brantley Hall, Kathleen Lake, Carol J. Landers, Himel Mallick, Damian R. Plichta, Mahadev Prasad, Gholamali Rahnavard, Jenny Sauk, Dmitry Shungin, Yoshiki Vázquez-Baeza, Richard A. White, Jonathan Braun, Lee A. Denson, Janet K. Jansson, Rob Knight, Subra Kugathasan, Dermot P. B. McGovern, Joseph F. Petrosino, Thaddeus S. Stappenbeck, Harland S. Winter, Clary B. Clish, Eric A. Franzosa, Hera Vlamakis, Ramnik J. Xavier and Curtis Huttenhower

Longitudinal multi-omics of host–microbe dynamics in prediabetes pp. 663-671

Wenyu Zhou, M. Reza Sailani, Kévin Contrepois, Yanjiao Zhou, Sara Ahadi, Shana R. Leopold, Martin J. Zhang, Varsha Rao, Monika Avina, Tejaswini Mishra, Jethro Johnson, Brittany Lee-McMullen, Songjie Chen, Ahmed A. Metwally, Thi Dong Binh Tran, Hoan Nguyen, Xin Zhou, Brandon Albright, Bo-Young Hong, Lauren Petersen, Eddy Bautista, Blake Hanson, Lei Chen, Daniel Spakowicz, Amir Bahmani, Denis Salins, Benjamin Leopold, Melanie Ashland, Orit Dagan-Rosenfeld, Shannon Rego, Patricia Limcaoco, Elizabeth Colbert, Candice Allister, Dalia Perelman, Colleen Craig, Eric Wei, Hassan Chaib, Daniel Hornburg, Jessilyn Dunn, Liang Liang, Sophia Miryam Schüssler-Fiorenza Rose, Kim Kukurba, Brian Piening, Hannes Rost, David Tse, Tracey McLaughlin, Erica Sodergren, George M. Weinstock and Michael Snyder

Progenitors from the central nervous system drive neurogenesis in cancer pp. 672-678

Philippe Mauffrey, Nicolas Tchitchek, Vilma Barroca, Alexis-Pierre Bemelmans, Virginie Firlej, Yves Allory, Paul-Henri Roméo and Claire Magnon

Mitochondrial protein translocation-associated degradation pp. 679-683

Christoph U. Mårtensson, Chantal Priesnitz, Jiyao Song, Lars Ellenrieder, Kim Nguyen Doan, Felix Boos, Alessia Floerchinger, Nicole Zufall, Silke Oeljeklaus, Bettina Warscheid and Thomas Becker

A massive white-dwarf merger product before final collapse pp. 684-687

Vasilii V. Gvaramadze, Götz Gräfener, Norbert Langer, Olga V. Maryeva, Alexei Y. Kniazev, Alexander S. Moskvitin and Olga I. Spiridonova

Observation of thermal Hawking radiation and its temperature in an analogue black hole pp. 688-691

Juan Ramón Muñoz de Nova, Katrine Golubkov, Victor I. Kolobov and Jeff Steinhauer

Cavity quantum electrodynamics with atom-like mirrors pp. 692-697

Mohammad Mirhosseini, Eunjong Kim, Xueyue Zhang, Alp Sipahigil, Paul B. Dieterle, Andrew J. Keller, Ana Asenjo-Garcia, Darrick E. Chang and Oskar Painter

Learning the signatures of the human grasp using a scalable tactile glove pp. 698-702

Subramanian Sundaram, Petr Kellnhofer, Yunzhu Li, Jun-Yan Zhu, Antonio Torralba and Wojciech Matusik

Quaternary-centre-guided synthesis of complex polycyclic terpenes pp. 703-707

Pengfei Hu, Hyung Min Chi, Kenneth C. DeBacker, Xu Gong, Jonathan H. Keim, Ian Tingyung Hsu and Scott A. Snyder

Sensory experience remodels genome architecture in neural circuit to drive motor learning pp. 708-713

Tomoko Yamada, Yue Yang, Pamela Valnegri, Ivan Juric, Armen Abnousi, Kelly H. Markwalter, Arden N. Guthrie, Abigail Godec, Anna Oldenborg, Ming Hu, Timothy E. Holy and Azad Bonni

An apical hypoxic niche sets the pace of shoot meristem activity pp. 714-717

Daan A. Weits, Alicja B. Kunkowska, Nicholas C. W. Kamps, Katharina M. S. Portz, Niko K. Packbier, Zoe Nemec Venza, Christophe Gaillochet, Jan U. Lohmann, Ole Pedersen, Joost T. Dongen and Francesco Licausi

A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1 pp. 718-722

Baoyu Zhao, Fenglei Du, Pengbiao Xu, Chang Shu, Banumathi Sankaran, Samantha L. Bell, Mengmeng Liu, Yuanjiu Lei, Xinsheng Gao, Xiaofeng Fu, Fanxiu Zhu, Yang Liu, Arthur Laganowsky, Xueyun Zheng, Jun-Yuan Ji, A. Phillip West, Robert O. Watson and Pingwei Li

Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts pp. 723-728

Mark A. Eckert, Fabian Coscia, Agnieszka Chryplewicz, Jae Won Chang, Kyle M. Hernandez, Shawn Pan, Samantha M. Tienda, Dominik A. Nahotko, Gang Li, Ivana Blaženović, Ricardo R. Lastra, Marion Curtis, S. Diane Yamada, Ruth Perets, Stephanie M. McGregor, Jorge Andrade, Oliver Fiehn, Raymond E. Moellering, Matthias Mann and Ernst Lengyel

Genome–lamina interactions are established de novo in the early mouse embryo pp. 729-733

Máté Borsos, Sara M. Perricone, Tamás Schauer, Julien Pontabry, Kim L. Luca, Sandra S. Vries, Elias R. Ruiz-Morales, Maria-Elena Torres-Padilla and Jop Kind

Active chromatin marks drive spatial sequestration of heterochromatin in C. elegans nuclei pp. 734-739

Daphne S. Cabianca, Celia Muñoz-Jiménez, Véronique Kalck, Dimos Gaidatzis, Jan Padeken, Andrew Seeber, Peter Askjaer and Susan M. Gasser

How a failed scientific start-up can breed success pp. 741-743

Amber Dance

In the spaces of strangers pp. 746-746

L. P. Lee

2019, volume 569, articles 7757

Author Correction: Observation of moiré excitons in WSe2/WS2 heterostructure superlattices pp. E7-E7

Chenhao Jin, Emma C. Regan, Aiming Yan, M. Iqbal Bakti Utama, Danqing Wang, Sihan Zhao, Ying Qin, Sijie Yang, Zhiren Zheng, Shenyang Shi, Kenji Watanabe, Takashi Taniguchi, Sefaattin Tongay, Alex Zettl and Feng Wang

Author Correction: Future response of global coastal wetlands to sea-level rise pp. E8-E8

Mark Schuerch, Tom Spencer, Stijn Temmerman, Matthew L. Kirwan, Claudia Wolff, Daniel Lincke, Chris J. McOwen, Mark D. Pickering, Ruth Reef, Athanasios T. Vafeidis, Jochen Hinkel, Robert J. Nicholls and Sally Brown

Publisher Correction: Electron magnetic reconnection without ion coupling in Earth’s turbulent magnetosheath pp. E9-E9

T. D. Phan, J. P. Eastwood, M. A. Shay, J. F. Drake, B. U. Ö. Sonnerup, M. Fujimoto, P. A. Cassak, M. Øieroset, J. L. Burch, R. B. Torbert, A. C. Rager, J. C. Dorelli, D. J. Gershman, C. Pollock, P. S. Pyakurel, C. C. Haggerty, Y. Khotyaintsev, B. Lavraud, Y. Saito, M. Oka, R. E. Ergun, A. Retino, O. Contel, M. R. Argall, B. L. Giles, T. E. Moore, F. D. Wilder, R. J. Strangeway, C. T. Russell, P. A. Lindqvist and W. Magnes

How China will protect one-quarter of its land pp. 457-457

Jixi Gao

Mystery of deadly Indonesian tsunami cracked using social-media videos pp. 463-464

Michael Marshall

Long-term studies will track indelible marks of first flu pp. 464-465

Declan Butler

Harassment survivors demand stronger action by US biomedical agency pp. 465-465

Sara Reardon

Italian physicists to stand trial for conditions in underground lab pp. 466-466

Nicola Nosengo

The devastating biological consequences of homelessness pp. 467-468

Amy Maxmen

Science in Europe: by the numbers pp. 470-471

Richard Van Noorden and Declan Butler

How European scientists will spend €100 billion pp. 472-475

Alison Abbott and Quirin Schiermeier

Europe’s controversial plans to expand defence research pp. 476-477

Elizabeth Gibney

Europe the rule-maker pp. 479-481

James Wilsdon and Sarah de Rijcke

Views from a continent in flux pp. 481-484

Carlos Moedas, Isabelle Vernos, Stephan Kuster, Helga Nowotny, Andrea Saltelli, Alina Mungiu-Pippidi, Jan Wouter Vasbinder, Daniel R. Brooks and Patrick Cunningham

Altered minds: mescaline’s complicated history pp. 485-486

Alison Abbott

Colombia: new plan imperils Amazon pp. 487-487

Dolors Armenteras and Thomas Defler

Stats: retain significance testing pp. 487-487

Brian Haig

More haste, less speed in replenishing China’s groundwater pp. 487-487

David O’Connor and Deyi Hou

One million species to go extinct — a decades-old headline pp. 487-487

Richard J. Ladle

Stats: 800 signatories on death warrant is overkill pp. 487-487

Frederick E. Lepore

A dam or an ape — Indonesia faces stark choice pp. 487-487

Erik Meijaard

Paul Greengard (1925–2019) pp. 488-488

Georgina Ferry

An ‘on’ switch for proteins pp. 490-491

Klaus Michael Hahn

Superconductivity near room temperature pp. 491-492

James J. Hamlin

Construction of an Escherichia coli genome with fewer codons sets records pp. 492-494

Benjamin A. Blount and Tom Ellis

Quantum gases show flashes of a supersolid pp. 494-495

Lode Pollet

A twist in the tale of the structure of ice pp. 495-496

John S. Tse

Distinct modes of cell competition shape mammalian tissue morphogenesis pp. 497-502

Stephanie J. Ellis, Nicholas C. Gomez, John Levorse, Aaron F. Mertz, Yejing Ge and Elaine Fuchs

Next-generation characterization of the Cancer Cell Line Encyclopedia pp. 503-508

Mahmoud Ghandi, Franklin W. Huang, Judit Jané-Valbuena, Gregory V. Kryukov, Christopher C. Lo, E. Robert McDonald, Jordi Barretina, Ellen T. Gelfand, Craig M. Bielski, Haoxin Li, Kevin Hu, Alexander Y. Andreev-Drakhlin, Jaegil Kim, Julian M. Hess, Brian J. Haas, François Aguet, Barbara A. Weir, Michael V. Rothberg, Brenton R. Paolella, Michael S. Lawrence, Rehan Akbani, Yiling Lu, Hong L. Tiv, Prafulla C. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, Juliann Shih, Kevin Hadi, Yanay Rosen, Jonathan Bistline, Kavitha Venkatesan, Anupama Reddy, Dmitriy Sonkin, Manway Liu, Joseph Lehar, Joshua M. Korn, Dale A. Porter, Michael D. Jones, Javad Golji, Giordano Caponigro, Jordan E. Taylor, Caitlin M. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, Audrey Kauffmann, Nicolas Stransky, Marcin Imielinski, Yosef E. Maruvka, Andrew D. Cherniack, Aviad Tsherniak, Francisca Vazquez, Jacob D. Jaffe, Andrew A. Lane, David M. Weinstock, Cory M. Johannessen, Michael P. Morrissey, Frank Stegmeier, Robert Schlegel, William C. Hahn, Gad Getz, Gordon B. Mills, Jesse S. Boehm, Todd R. Golub, Levi A. Garraway and William R. Sellers

Time-resolved protein activation by proximal decaging in living systems pp. 509-513

Jie Wang, Yuan Liu, Yanjun Liu, Siqi Zheng, Xin Wang, Jingyi Zhao, Fan Yang, Gong Zhang, Chu Wang and Peng R. Chen

Total synthesis of Escherichia coli with a recoded genome pp. 514-518

Julius Fredens, Kaihang Wang, Daniel Torre, Louise F. H. Funke, Wesley E. Robertson, Yonka Christova, Tiongsun Chia, Wolfgang H. Schmied, Daniel L. Dunkelmann, Václav Beránek, Chayasith Uttamapinant, Andres Gonzalez Llamazares, Thomas S. Elliott and Jason W. Chin

Fast and inefficient star formation due to short-lived molecular clouds and rapid feedback pp. 519-522

J. M. Diederik Kruijssen, Andreas Schruba, Mélanie Chevance, Steven N. Longmore, Alexander P. S. Hygate, Daniel T. Haydon, Anna F. McLeod, Julianne J. Dalcanton, Linda J. Tacconi and Ewine F. Dishoeck

The rheology and thermal history of Mars revealed by the orbital evolution of Phobos pp. 523-527

Henri Samuel, Philippe Lognonné, Mark Panning and Valéry Lainey

Superconductivity at 250 K in lanthanum hydride under high pressures pp. 528-531

A. P. Drozdov, P. P. Kong, V. S. Minkov, S. P. Besedin, M. A. Kuzovnikov, S. Mozaffari, L. Balicas, F. F. Balakirev, D. E. Graf, V. B. Prakapenka, E. Greenberg, D. A. Knyazev, M. Tkacz and M. I. Eremets

Fidelity benchmarks for two-qubit gates in silicon pp. 532-536

W. Huang, C. H. Yang, K. W. Chan, T. Tanttu, B. Hensen, R. C. C. Leon, M. A. Fogarty, J. C. C. Hwang, F. E. Hudson, K. M. Itoh, A. Morello, A. Laucht and A. S. Dzurak

Three-dimensional quantum Hall effect and metal–insulator transition in ZrTe5 pp. 537-541

Fangdong Tang, Yafei Ren, Peipei Wang, Ruidan Zhong, John Schneeloch, Shengyuan A. Yang, Kun Yang, Patrick A. Lee, Genda Gu, Zhenhua Qiao and Liyuan Zhang

Absence of amorphous forms when ice is compressed at low temperature pp. 542-545

Chris A. Tulk, Jamie J. Molaison, Adam R. Makhluf, Craig E. Manning and Dennis D. Klug

Increase in CFC-11 emissions from eastern China based on atmospheric observations pp. 546-550

M. Rigby, S. Park, T. Saito, L. M. Western, A. L. Redington, X. Fang, S. Henne, A. J. Manning, R. G. Prinn, G. S. Dutton, P. J. Fraser, A. L. Ganesan, B. D. Hall, C. M. Harth, J. Kim, K.-R. Kim, P. B. Krummel, T. Lee, S. Li, Q. Liang, M. F. Lunt, S. A. Montzka, J. Mühle, S. O’Doherty, M.-K. Park, S. Reimann, P. K. Salameh, P. Simmonds, R. L. Tunnicliffe, R. F. Weiss, Y. Yokouchi and D. Young

Industrial-era decline in subarctic Atlantic productivity pp. 551-555

Matthew B. Osman, Sarah B. Das, Luke D. Trusel, Matthew J. Evans, Hubertus Fischer, Mackenzie M. Grieman, Sepp Kipfstuhl, Joseph R. McConnell and Eric S. Saltzman

Neurocranial development of the coelacanth and the evolution of the sarcopterygian head pp. 556-559

Hugo Dutel, Manon Galland, Paul Tafforeau, John A. Long, Michael J. Fagan, Philippe Janvier, Anthony Herrel, Mathieu D. Santin, Gaël Clément and Marc Herbin

Genomic characterization of metastatic breast cancers pp. 560-564

François Bertucci, Charlotte K. Y. Ng, Anne Patsouris, Nathalie Droin, Salvatore Piscuoglio, Nadine Carbuccia, Jean Charles Soria, Alicia Tran Dien, Yahia Adnani, Maud Kamal, Séverine Garnier, Guillaume Meurice, Marta Jimenez, Semih Dogan, Benjamin Verret, Max Chaffanet, Thomas Bachelot, Mario Campone, Claudia Lefeuvre, Herve Bonnefoi, Florence Dalenc, Alexandra Jacquet, Maria R. Filippo, Naveen Babbar, Daniel Birnbaum, Thomas Filleron, Christophe Tourneau and Fabrice André

SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis pp. 565-569

Linzhang Huang, Ken L. Chambliss, Xiaofei Gao, Ivan S. Yuhanna, Erica Behling-Kelly, Sonia Bergaya, Mohamed Ahmed, Peter Michaely, Kate Luby-Phelps, Anza Darehshouri, Lin Xu, Edward A. Fisher, Woo-Ping Ge, Chieko Mineo and Philip W. Shaul

NAD metabolic dependency in cancer is shaped by gene amplification and enhancer remodelling pp. 570-575

Sudhir Chowdhry, Ciro Zanca, Utkrisht Rajkumar, Tomoyuki Koga, Yarui Diao, Ramya Raviram, Feng Liu, Kristen Turner, Huijun Yang, Elizabeth Brunk, Junfeng Bi, Frank Furnari, Vineet Bafna, Bing Ren and Paul S. Mischel

Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia pp. 576-580

Federico Gaiti, Ronan Chaligne, Hongcang Gu, Ryan M. Brand, Steven Kothen-Hill, Rafael C. Schulman, Kirill Grigorev, Davide Risso, Kyu-Tae Kim, Alessandro Pastore, Kevin Y. Huang, Alicia Alonso, Caroline Sheridan, Nathaniel D. Omans, Evan Biederstedt, Kendell Clement, Lili Wang, Joshua A. Felsenfeld, Erica B. Bhavsar, Martin J. Aryee, John N. Allan, Richard Furman, Andreas Gnirke, Catherine J. Wu, Alexander Meissner and Dan A. Landau

A vitamin-C-derived DNA modification catalysed by an algal TET homologue pp. 581-585

Jian-Huang Xue, Guo-Dong Chen, Fuhua Hao, Hui Chen, Zhaoyuan Fang, Fang-Fang Chen, Bo Pang, Qing-Lin Yang, Xinben Wei, Qiang-Qiang Fan, Changpeng Xin, Jiaohong Zhao, Xuan Deng, Bang-An Wang, Xiao-Jie Zhang, Yueying Chu, Hui Tang, Huiyong Yin, Weimin Ma, Luonan Chen, Jianping Ding, Elmar Weinhold, Rahul M. Kohli, Wen Liu, Zheng-Jiang Zhu, Kaiyao Huang, Huiru Tang and Guo-Liang Xu

A DIY approach to automating your lab pp. 587-588

Mike May

Europe is a top destination for many researchers pp. 589-591

Quirin Schiermeier

It’s all my fault, or the Beanstalk sucks pp. 594-594

Ian Randal Strock

2019, volume 569, articles 7756

Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells pp. E4-E4

Jiyeon Kim, Zeping Hu, Ling Cai, Kailong Li, Eunhee Choi, Brandon Faubert, Divya Bezwada, Jaime Rodriguez-Canales, Pamela Villalobos, Yu-Fen Lin, Min Ni, Kenneth E. Huffman, Luc Girard, Lauren A. Byers, Keziban Unsal-Kacmaz, Christopher G. Peña, John V. Heymach, Els Wauters, Johan Vansteenkiste, Diego H. Castrillon, Benjamin P. C. Chen, Ignacio Wistuba, Diether Lambrechts, Jian Xu, John D. Minna and Ralph J. DeBerardinis

Small advances amount to big changes in biomedical sciences pp. S5-S5

Catherine Armitage

Author Correction: Attosecond angular streaking and tunnelling time in atomic hydrogen pp. E5-E5

U. Satya Sainadh, Han Xu, Xiaoshan Wang, A. Atia-Tul-Noor, William C. Wallace, Nicolas Douguet, Alexander Bray, Igor Ivanov, Klaus Bartschat, Anatoli Kheifets, R. T. Sang and I. V. Litvinyuk

Publisher Correction: Structural basis of ligand recognition at the human MT1 melatonin receptor pp. E6-E6

Benjamin Stauch, Linda C. Johansson, John D. McCorvy, Nilkanth Patel, Gye Won Han, Xi-Ping Huang, Cornelius Gati, Alexander Batyuk, Samuel T. Slocum, Andrii Ishchenko, Wolfgang Brehm, Thomas A. White, Nairie Michaelian, Caleb Madsen, Lan Zhu, Thomas D. Grant, Jessica M. Grandner, Anna Shiriaeva, Reid H. J. Olsen, Alexandra R. Tribo, Saïd Yous, Raymond C. Stevens, Uwe Weierstall, Vsevolod Katritch, Bryan L. Roth, Wei Liu and Vadim Cherezov

Rapid progress transforms ideals of health pp. S6-S7

Bianca Nogrady

New tools for new treatments pp. S10-S12

Jennifer Cooke and Bec Crew

Lili Milani banks Estonia’s genomic potential pp. S16-S17

Bec Crew

Companies persist with biomedical papers pp. S18-S19

Ashish Arora, Sharon Belenzon, Wesley Cohen and Andrea Patacconi

Stem-cell and genetic therapies make a healthy marriage pp. S23-S25

Bianca Nogrady

Vaccination lags behind in middle-income countries pp. 309-309

Seth Berkley

US environment agency cuts funding for kids’ health studies pp. 315-317

Sara Reardon

Artificial intelligence is selecting grant reviewers in China pp. 316-317

David Cyranoski

Intolerance and funding concern Indian scientists ahead of election pp. 317-318

T. V. Padma

Brazilian biomedical science faces reproducibility test pp. 318-319

Rodrigo de Oliveira Andrade

Russia joins in global gene-editing bonanza pp. 319-320

Olga Dobrovidova

The trickster microbes that are shaking up the tree of life pp. 322-324

Traci Watson

Chinese investments fuel growth in African science pp. 325-326

Antoaneta Roussi

Put equity first in climate adaptation pp. 327-329

Mark Pelling and Matthias Garschagen

Deploy diverse renewables to save tropical rivers pp. 330-332

Rafael J. P. Schmitt, Noah Kittner, G. Mathias Kondolf and Daniel M. Kammen

Brain in a dish, babies by design: what it means to be human pp. 333-334

Natalie Kofler

A bird-based game takes wing pp. 334-335

Stuart West

The future of genetic engineering, a treasure trove of insects, and a love letter to getting lost: Books in brief pp. 335-335

Barbara Kiser

Stats: a trillion P values and counting pp. 336-336

Hieab H. H. Adams

Don’t muddy Walter Munk’s legacy pp. 336-336

Ann E. Bowles

French cuts to research jobs could fuel brain drain pp. 336-336

Guillaume Gaullier

Stats: P values akin to ‘beyond reasonable doubt’ pp. 336-336

Heping Zhang

EU must outlaw ivory trade before laxity derails other bans pp. 336-336

Li Zhang and Ning Hua

The Moon’s mantle unveiled pp. 338-339

Patrick Pinet

Scaling up quantum simulations pp. 339-340

Jürgen Berges

Protein assembles into Archimedean geometry pp. 340-342

Todd O. Yeates

A map of β-cell differentiation pathways supports cell therapies for diabetes pp. 342-343

Fabian J. Theis and Heiko Lickert

Manipulating the tumour-suppressor protein Rb in lung cancer reveals possible drug targets pp. 343-344

Seth M. Rubin and Julien Sage

Transcription factors and 3D genome conformation in cell-fate decisions pp. 345-354

Ralph Stadhouders, Guillaume J. Filion and Thomas Graf

Self-verifying variational quantum simulation of lattice models pp. 355-360

C. Kokail, C. Maier, R. van Bijnen, T. Brydges, M. K. Joshi, P. Jurcevic, C. A. Muschik, P. Silvi, R. Blatt, C. F. Roos and P. Zoller

The emergent landscape of the mouse gut endoderm at single-cell resolution pp. 361-367

Sonja Nowotschin, Manu Setty, Ying-Yi Kuo, Vincent Liu, Vidur Garg, Roshan Sharma, Claire S. Simon, Nestor Saiz, Rui Gardner, Stéphane C. Boutet, Deanna M. Church, Pamela A. Hoodless, Anna-Katerina Hadjantonakis and Dana Pe’er

Charting cellular identity during human in vitro β-cell differentiation pp. 368-373

Adrian Veres, Aubrey L. Faust, Henry L. Bushnell, Elise N. Engquist, Jennifer Hyoje-Ryu Kenty, George Harb, Yeh-Chuin Poh, Elad Sintov, Mads Gürtler, Felicia W. Pagliuca, Quinn P. Peterson and Douglas A. Melton

A rapidly changing jet orientation in the stellar-mass black-hole system V404 Cygni pp. 374-377

James C. A. Miller-Jones, Alexandra J. Tetarenko, Gregory R. Sivakoff, Matthew J. Middleton, Diego Altamirano, Gemma E. Anderson, Tomaso M. Belloni, Rob P. Fender, Peter G. Jonker, Elmar G. Körding, Hans A. Krimm, Dipankar Maitra, Sera Markoff, Simone Migliari, Kunal P. Mooley, Michael P. Rupen, David M. Russell, Thomas D. Russell, Craig L. Sarazin, Roberto Soria and Valeriu Tudose

Chang’E-4 initial spectroscopic identification of lunar far-side mantle-derived materials pp. 378-382

Chunlai Li, Dawei Liu, Bin Liu, Xin Ren, Jianjun Liu, Zhiping He, Wei Zuo, Xingguo Zeng, Rui Xu, Xu Tan, Xiaoxia Zhang, Wangli Chen, Rong Shu, Weibin Wen, Yan Su, Hongbo Zhang and Ziyuan Ouyang

Temporal and spectral fingerprints of ultrafast all-coherent spin switching pp. 383-387

S. Schlauderer, C. Lange, S. Baierl, T. Ebnet, C. P. Schmid, D. C. Valovcin, A. K. Zvezdin, A. V. Kimel, R. V. Mikhaylovskiy and R. Huber

Subthreshold firing in Mott nanodevices pp. 388-392

Javier del Valle, Pavel Salev, Federico Tesler, Nicolás M. Vargas, Yoav Kalcheim, Paul Wang, Juan Trastoy, Min-Han Lee, George Kassabian, Juan Gabriel Ramírez, Marcelo J. Rozenberg and Ivan K. Schuller

Atomic rheology of gold nanojunctions pp. 393-397

Jean Comtet, Antoine Lainé, Antoine Niguès, Lydéric Bocquet and Alessandro Siria

Sampling the volatile-rich transition zone beneath Bermuda pp. 398-403

Sarah E. Mazza, Esteban Gazel, Michael Bizimis, Robert Moucha, Paul Béguelin, Elizabeth A. Johnson, Ryan J. McAleer and Alexander V. Sobolev

Climatic controls of decomposition drive the global biogeography of forest-tree symbioses pp. 404-408

B. S. Steidinger, T. W. Crowther, J. Liang, M. E. Nuland, G. D. A. Werner, P. B. Reich, G. J. Nabuurs, S. de-Miguel, M. Zhou, N. Picard, B. Herault, X. Zhao, C. Zhang, D. Routh and K. G. Peay

A late Middle Pleistocene Denisovan mandible from the Tibetan Plateau pp. 409-412

Fahu Chen, Frido Welker, Chuan-Chou Shen, Shara E. Bailey, Inga Bergmann, Simon Davis, Huan Xia, Hui Wang, Roman Fischer, Sarah E. Freidline, Tsai-Luen Yu, Matthew M. Skinner, Stefanie Stelzer, Guangrong Dong, Qiaomei Fu, Guanghui Dong, Jian Wang, Dongju Zhang and Jean-Jacques Hublin

Voltage imaging and optogenetics reveal behaviour-dependent changes in hippocampal dynamics pp. 413-417

Yoav Adam, Jeong J. Kim, Shan Lou, Yongxin Zhao, Michael E. Xie, Daan Brinks, Hao Wu, Mohammed A. Mostajo-Radji, Simon Kheifets, Vicente Parot, Selmaan Chettih, Katherine J. Williams, Benjamin Gmeiner, Samouil L. Farhi, Linda Madisen, E. Kelly Buchanan, Ian Kinsella, Ding Zhou, Liam Paninski, Christopher D. Harvey, Hongkui Zeng, Paola Arlotta, Robert E. Campbell and Adam E. Cohen

MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs pp. 418-422

Khatia Gabisonia, Giulia Prosdocimo, Giovanni Donato Aquaro, Lucia Carlucci, Lorena Zentilin, Ilaria Secco, Hashim Ali, Luca Braga, Nikoloz Gorgodze, Fabio Bernini, Silvia Burchielli, Chiara Collesi, Lorenzo Zandonà, Gianfranco Sinagra, Marcello Piacenti, Serena Zacchigna, Rossana Bussani, Fabio A. Recchia and Mauro Giacca

RB constrains lineage fidelity and multiple stages of tumour progression and metastasis pp. 423-427

David M. Walter, Travis J. Yates, Miguel Ruiz-Torres, Caroline Kim-Kiselak, A. Andrea Gudiel, Charuhas Deshpande, Walter Z. Wang, Michelle Cicchini, Kate L. Stokes, John W. Tobias, Elizabeth Buza and David M. Feldser

Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy pp. 428-432

Elisabeth Perez-Ruiz, Luna Minute, Itziar Otano, Maite Alvarez, Maria Carmen Ochoa, Virginia Belsue, Carlos de Andrea, Maria Esperanza Rodriguez-Ruiz, Jose Luis Perez-Gracia, Ivan Marquez-Rodas, Casilda Llacer, Martina Alvarez, Vanesa de Luque, Carmen Molina, Alvaro Teijeira, Pedro Berraondo and Ignacio Melero

Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors pp. 433-437

Julian Grünewald, Ronghao Zhou, Sara P. Garcia, Sowmya Iyer, Caleb A. Lareau, Martin J. Aryee and J. Keith Joung

An ultra-stable gold-coordinated protein cage displaying reversible assembly pp. 438-442

Ali D. Malay, Naoyuki Miyazaki, Artur Biela, Soumyananda Chakraborti, Karolina Majsterkiewicz, Izabela Stupka, Craig S. Kaplan, Agnieszka Kowalczyk, Bernard M. A. G. Piette, Georg K. A. Hochberg, Di Wu, Tomasz P. Wrobel, Adam Fineberg, Manish S. Kushwah, Mitja Kelemen, Primož Vavpetič, Primož Pelicon, Philipp Kukura, Justin L. P. Benesch, Kenji Iwasaki and Jonathan G. Heddle

Data sharing and how it can benefit your scientific career pp. 445-447

Gabriel Popkin

Remember pp. 450-450

A. J. Lee

2019, volume 569, articles 7755

Biosimilars: mimicking biological drugs pp. S1-S1

Michael Eisenstein

Bring on the biosimilars pp. S2-S3

Michael Eisenstein

Author Correction: Single-cell analysis of mixed-lineage states leading to a binary cell fate choice pp. E3-E3

Andre Olsson, Meenakshi Venkatasubramanian, Virendra K. Chaudhri, Bruce J. Aronow, Nathan Salomonis, Harinder Singh and H. Leighton Grimes

Don’t let industry write the rules for AI pp. 161-161

Yochai Benkler

EXCLUSIVE: UK to open first ‘body farm’ for forensic research pp. 167-168

David Adam

US science academy leaders approve plan to expel sexual harassers pp. 168-168

Sara Reardon

Trump’s science adviser on research ethics, immigration and presidential tweets pp. 169-170

Sara Reardon

Chinese hospitals set to sell experimental cell therapies pp. 170-171

David Cyranoski

Humans are driving one million species to extinction pp. 171-171

Jeff Tollefson

Cannabis used in US research differs genetically to the varieties people smoke pp. 172-172

Sara Reardon

China charts a path into European science pp. 174-176

Antoaneta Roussi

South America is embracing Beijing’s science silk road pp. 177-179

Lucien O. Chauvin and Barbara Fraser

Fix the broken food system in three steps pp. 181-183

Guido Schmidt-Traub, Michael Obersteiner and Aline Mosnier

Reboot ethics governance in China pp. 184-186

Ruipeng Lei, Xiaomei Zhai, Wei Zhu and Renzong Qiu

The fascinating and terrifying worlds beneath our feet pp. 188-189

Huw Lewis-Jones

The sounds of science: biochemistry and the cosmos inspire new music pp. 190-191

Elie Dolgin

The science of magic, dung beetles on parade, and the unexplored depths: Books in brief pp. 191-191

Andrew Robinson

Stats: is this therapy useful? pp. 192-192

Matthew Kramer

Stats: abuse by researchers’ lust for certainty pp. 192-192

Ian F. Godsland

Stats: multiple experiments test biomedical conclusions pp. 192-192

Jeffrey S. Mogil

Internationalize hazard management of China’s chemical plants pp. 192-192

Hong Yang

Stop harvesting olives at night — it kills millions of songbirds pp. 192-192

Luis P. da Silva and Vanessa A. Mata

David J. Thouless (1934-2019) pp. 193-193

Andrea Taroni

Why brown fat has a lot of nerve pp. 196-197

Rejji Kuruvilla

Pinpointing a spatial address for RNA profiles in tissues pp. 197-199

Samantha A. Morris

A role for optics in AI hardware pp. 199-200

Geoffrey W. Burr

Rural areas drive increases in global obesity pp. 200-201

Barry M. Popkin

A river that flows free connects up in 4D pp. 201-202

N. LeRoy Poff

All-optical spiking neurosynaptic networks with self-learning capabilities pp. 208-214

J. Feldmann, N. Youngblood, C. D. Wright, H. Bhaskaran and W. H. P. Pernice

Mapping the world’s free-flowing rivers pp. 215-221

G. Grill, B. Lehner, M. Thieme, B. Geenen, D. Tickner, F. Antonelli, S. Babu, P. Borrelli, L. Cheng, H. Crochetiere, H. Ehalt Macedo, R. Filgueiras, M. Goichot, J. Higgins, Z. Hogan, B. Lip, M. E. McClain, J. Meng, M. Mulligan, C. Nilsson, J. D. Olden, J. J. Opperman, P. Petry, C. Reidy Liermann, L. Sáenz, S. Salinas-Rodríguez, P. Schelle, R. J. P. Schmitt, J. Snider, F. Tan, K. Tockner, P. H. Valdujo, A. Soesbergen and C. Zarfl

The bone marrow microenvironment at single-cell resolution pp. 222-228

Anastasia N. Tikhonova, Igor Dolgalev, Hai Hu, Kishor K. Sivaraj, Edlira Hoxha, Álvaro Cuesta-Domínguez, Sandra Pinho, Ilseyar Akhmetzyanova, Jie Gao, Matthew Witkowski, Maria Guillamot, Michael C. Gutkin, Yutong Zhang, Christian Marier, Catherine Diefenbach, Stavroula Kousteni, Adriana Heguy, Hua Zhong, David R. Fooksman, Jason M. Butler, Aris Economides, Paul S. Frenette, Ralf H. Adams, Rahul Satija, Aristotelis Tsirigos and Iannis Aifantis

Innervation of thermogenic adipose tissue via a calsyntenin 3β–S100b axis pp. 229-235

Xing Zeng, Mengchen Ye, Jon M. Resch, Mark P. Jedrychowski, Bo Hu, Bradford B. Lowell, David D. Ginty and Bruce M. Spiegelman

Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death pp. 236-240

Carlos Silvestre-Roig, Quinte Braster, Kanin Wichapong, Ernest Y. Lee, Jean Marie Teulon, Nihel Berrebeh, Janine Winter, José M. Adrover, Giancarlo Santiago Santos, Alexander Froese, Patricia Lemnitzer, Almudena Ortega-Gómez, Raphael Chevre, Julian Marschner, Ariane Schumski, Carla Winter, Laura Perez-Olivares, Chang Pan, Nicole Paulin, Tom Schoufour, Helene Hartwig, Silvia González-Ramos, Frits Kamp, Remco T. A. Megens, Kerri A. Mowen, Matthias Gunzer, Lars Maegdefessel, Tilman Hackeng, Esther Lutgens, Mat Daemen, Julia Blume, Hans-Joachim Anders, Viacheslav O. Nikolaev, Jean-Luc Pellequer, Christian Weber, Andrés Hidalgo, Gerry A. F. Nicolaes, Gerard C. L. Wong and Oliver Soehnlein

Collapsars as a major source of r-process elements pp. 241-244

Daniel M. Siegel, Jennifer Barnes and Brian D. Metzger

Aqueous Li-ion battery enabled by halogen conversion–intercalation chemistry in graphite pp. 245-250

Chongyin Yang, Ji Chen, Xiao Ji, Travis P. Pollard, Xujie Lü, Cheng-Jun Sun, Singyuk Hou, Qi Liu, Cunming Liu, Tingting Qing, Yingqi Wang, Oleg Borodin, Yang Ren, Kang Xu and Chunsheng Wang

Nanosecond X-ray diffraction of shock-compressed superionic water ice pp. 251-255

Marius Millot, Federica Coppari, J. Ryan Rygg, Antonio Correa Barrios, Sebastien Hamel, Damian C. Swift and Jon H. Eggert

A new Jurassic scansoriopterygid and the loss of membranous wings in theropod dinosaurs pp. 256-259

Min Wang, Jingmai K. O’Connor, Xing Xu and Zhonghe Zhou

Arabidopsis FLL2 promotes liquid–liquid phase separation of polyadenylation complexes pp. 265-269

Xiaofeng Fang, Liang Wang, Ryo Ishikawa, Yaoxi Li, Marc Fiedler, Fuquan Liu, Grant Calder, Beth Rowan, Detlef Weigel, Pilong Li and Caroline Dean

CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy pp. 270-274

Weimin Wang, Michael Green, Jae Eun Choi, Miguel Gijón, Paul D. Kennedy, Jeffrey K. Johnson, Peng Liao, Xueting Lang, Ilona Kryczek, Amanda Sell, Houjun Xia, Jiajia Zhou, Gaopeng Li, Jing Li, Wei Li, Shuang Wei, Linda Vatan, Hongjuan Zhang, Wojciech Szeliga, Wei Gu, Rebecca Liu, Theodore S. Lawrence, Candice Lamb, Yuri Tanno, Marcin Cieslik, Everett Stone, George Georgiou, Timothy A. Chan, Arul Chinnaiyan and Weiping Zou

LLGL2 rescues nutrient stress by promoting leucine uptake in ER+ breast cancer pp. 275-279

Yasuhiro Saito, Lewyn Li, Etienne Coyaud, Augustin Luna, Chris Sander, Brian Raught, John M. Asara, Myles Brown and Senthil K. Muthuswamy

Visualization of clustered protocadherin neuronal self-recognition complexes pp. 280-283

Julia Brasch, Kerry M. Goodman, Alex J. Noble, Micah Rapp, Seetha Mannepalli, Fabiana Bahna, Venkata P. Dandey, Tristan Bepler, Bonnie Berger, Tom Maniatis, Clinton S. Potter, Bridget Carragher, Barry Honig and Lawrence Shapiro

Structural basis of ligand recognition at the human MT1 melatonin receptor pp. 284-288

Benjamin Stauch, Linda C. Johansson, John D. McCorvy, Nilkanth Patel, Gye Won Han, Xi-Ping Huang, Cornelius Gati, Alexander Batyuk, Samuel T. Slocum, Andrii Ishchenko, Wolfgang Brehm, Thomas A. White, Nairie Michaelian, Caleb Madsen, Lan Zhu, Thomas D. Grant, Jessica M. Grandner, Anna Shiriaeva, Reid H. J. Olsen, Alexandra R. Tribo, Saïd Yous, Raymond C. Stevens, Uwe Weierstall, Vsevolod Katritch, Bryan L. Roth, Wei Liu and Vadim Cherezov

XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity pp. 289-292

Linda C. Johansson, Benjamin Stauch, John D. McCorvy, Gye Won Han, Nilkanth Patel, Xi-Ping Huang, Alexander Batyuk, Cornelius Gati, Samuel T. Slocum, Chufeng Li, Jessica M. Grandner, Shuming Hao, Reid H. J. Olsen, Alexandra R. Tribo, Sahba Zaare, Lan Zhu, Nadia A. Zatsepin, Uwe Weierstall, Saïd Yous, Raymond C. Stevens, Wei Liu, Bryan L. Roth, Vsevolod Katritch and Vadim Cherezov

The new techniques revealing the varied shapes of chromatin pp. 293-294

Jeffrey M. Perkel

Web annotation tool Hypothesis hits a milestone pp. 295-295

Rina Shaikh-Lesko

What scientists should know about visa hurdles pp. 297-299

Virginia Gewin

Brick city pp. 302-302

Robert S. Wilson

2019, volume 569, articles 7754

Publisher Correction: Martian dust storm impact on atmospheric H2O and D/H observed by ExoMars Trace Gas Orbiter pp. E1-E1

Ann Carine Vandaele, Oleg Korablev, Frank Daerden, Shohei Aoki, Ian R. Thomas, Francesca Altieri, Miguel López-Valverde, Geronimo Villanueva, Giuliano Liuzzi, Michael D. Smith, Justin T. Erwin, Loïc Trompet, Anna A. Fedorova, Franck Montmessin, Alexander Trokhimovskiy, Denis A. Belyaev, Nikolay I. Ignatiev, Mikhail Luginin, Kevin S. Olsen, Lucio Baggio, Juan Alday, Jean-Loup Bertaux, Daria Betsis, David Bolsée, R. Todd Clancy, Edward Cloutis, Cédric Depiesse, Bernd Funke, Maia Garcia-Comas, Jean-Claude Gérard, Marco Giuranna, Francisco Gonzalez-Galindo, Alexey V. Grigoriev, Yuriy S. Ivanov, Jacek Kaminski, Ozgur Karatekin, Franck Lefèvre, Stephen Lewis, Manuel López-Puertas, Arnaud Mahieux, Igor Maslov, Jon Mason, Michael J. Mumma, Lori Neary, Eddy Neefs, Andrey Patrakeev, Dmitry Patsaev, Bojan Ristic, Séverine Robert, Frédéric Schmidt, Alexey Shakun, Nicholas A. Teanby, Sébastien Viscardy, Yannick Willame, James Whiteway, Valérie Wilquet, Michael J. Wolff, Giancarlo Bellucci, Manish R. Patel, Jose-Juan López-Moreno, François Forget, Colin F. Wilson, Roland Young, Håkan Svedhem, Jorge L. Vago and Daniel Rodionov

Publisher Correction: No detection of methane on Mars from early ExoMars Trace Gas Orbiter observations pp. E2-E2

Oleg Korablev, Ann Carine Vandaele, Franck Montmessin, Anna A. Fedorova, Alexander Trokhimovskiy, François Forget, Franck Lefèvre, Frank Daerden, Ian R. Thomas, Loïc Trompet, Justin T. Erwin, Shohei Aoki, Séverine Robert, Lori Neary, Sébastien Viscardy, Alexey V. Grigoriev, Nikolay I. Ignatiev, Alexey Shakun, Andrey Patrakeev, Denis A. Belyaev, Jean-Loup Bertaux, Kevin S. Olsen, Lucio Baggio, Juan Alday, Yuriy S. Ivanov, Bojan Ristic, Jon Mason, Yannick Willame, Cédric Depiesse, Laszlo Hetey, Sophie Berkenbosch, Roland Clairquin, Claudio Queirolo, Bram Beeckman, Eddy Neefs, Manish R. Patel, Giancarlo Bellucci, Jose-Juan López-Moreno, Colin F. Wilson, Giuseppe Etiope, Lev Zelenyi, Håkan Svedhem and Jorge L. Vago

How to shape research to advance global health pp. 7-7

Soumya Swaminathan

Spread of deadly pig virus in China hastens vaccine research pp. 13-14

Smriti Mallapaty

First proven malaria vaccine rolled out in Africa — but doubts linger pp. 14-15

Amy Maxmen

Gravitational waves hint at detection of black hole eating star pp. 15-16

Davide Castelvecchi

Biggest Denisovan fossil yet spills ancient human’s secrets pp. 16-17

Matthew Warren

Global 5G wireless networks threaten weather forecasts pp. 17-18

Alexandra Witze

How China is redrawing the map of world science pp. 20-23

Ehsan Masood

Scientists in Pakistan and Sri Lanka bet their futures on China pp. 24-27

Ehsan Masood

Model and manage the changing geopolitics of energy pp. 29-31

Morgan Bazilian, Michael Bradshaw, Andreas Goldthau and Kirsten Westphal

Permafrost collapse is accelerating carbon release pp. 32-34

Merritt R. Turetsky, Benjamin W. Abbott, Miriam C. Jones, Katey Walter Anthony, David Olefeldt, Edward A. G. Schuur, Charles Koven, A. David McGuire, Guido Grosse, Peter Kuhry, Gustaf Hugelius, David M. Lawrence, Carolyn Gibson and A. Britta K. Sannel

The new physics needed to probe the origins of life pp. 36-38

Sara Imari Walker

Profits for the people, six millennia of cities, and the roots of sickness and health: Books in brief pp. 37-37

Barbara Kiser

Curating the cosmos: a lens on nature pp. 38-39

Amelia Hennighausen

Japan responds: stem-cell therapy justified pp. 40-40

Shinji Miyamoto

Germline editing: could ban encourage medical tourism? pp. 40-40

Eli Y. Adashi and I. Glenn Cohen

Account for sex in brain research for precision medicine pp. 40-40

Maria Teresa Ferretti, Antonella Santuccione-Chadha and Harald Hampel

What your research-integrity officer would like you to know pp. 40-40

Susan Garfinkel, Deborah E. Rupp, Lauran Qualkenbush and Christopher Lehmann

Mary Warnock (1924-2019) pp. 41-41

Sarah Franklin

Reconfiguration of a bacterial transport system generates a reverse gear pp. 44-45

Jorge E. Galán

The origin and spread of the Sino-Tibetan language family pp. 45-47

Randy J. LaPolla

A possible non-biological reaction framework for metabolic processes on early Earth pp. 47-49

Robert Pascal

A doubly magic nucleus that has two faces pp. 49-50

Gaute Hagen and Thomas Papenbrock

Sea animals are more vulnerable to warming than are land ones pp. 50-51

Anthony J. Richardson and David S. Schoeman

78Ni revealed as a doubly magic stronghold against nuclear deformation pp. 53-58

R. Taniuchi, C. Santamaria, P. Doornenbal, A. Obertelli, K. Yoneda, G. Authelet, H. Baba, D. Calvet, F. Château, A. Corsi, A. Delbart, J.-M. Gheller, A. Gillibert, J. D. Holt, T. Isobe, V. Lapoux, M. Matsushita, J. Menéndez, S. Momiyama, T. Motobayashi, M. Niikura, F. Nowacki, K. Ogata, H. Otsu, T. Otsuka, C. Péron, S. Péru, A. Peyaud, E. C. Pollacco, A. Poves, J.-Y. Roussé, H. Sakurai, A. Schwenk, Y. Shiga, J. Simonis, S. R. Stroberg, S. Takeuchi, Y. Tsunoda, T. Uesaka, H. Wang, F. Browne, L. X. Chung, Z. Dombradi, S. Franchoo, F. Giacoppo, A. Gottardo, K. Hadyńska-Klęk, Z. Korkulu, S. Koyama, Y. Kubota, J. Lee, M. Lettmann, C. Louchart, R. Lozeva, K. Matsui, T. Miyazaki, S. Nishimura, L. Olivier, S. Ota, Z. Patel, E. Şahin, C. Shand, P.-A. Söderström, I. Stefan, D. Steppenbeck, T. Sumikama, D. Suzuki, Z. Vajta, V. Werner, J. Wu and Z. Y. Xu

Twentieth-century hydroclimate changes consistent with human influence pp. 59-65

Kate Marvel, Benjamin I. Cook, Céline J. W. Bonfils, Paul J. Durack, Jason E. Smerdon and A. Park Williams

Self-organization and symmetry breaking in intestinal organoid development pp. 66-72

Denise Serra, Urs Mayr, Andrea Boni, Ilya Lukonin, Markus Rempfler, Ludivine Challet Meylan, Michael B. Stadler, Petr Strnad, Panagiotis Papasaikas, Dario Vischi, Annick Waldt, Guglielmo Roma and Prisca Liberali

Fatty acid transport protein 2 reprograms neutrophils in cancer pp. 73-78

Filippo Veglia, Vladimir A. Tyurin, Maria Blasi, Alessandra Leo, Andrew V. Kossenkov, Laxminarasimha Donthireddy, Tsun Ki Jerrick To, Zach Schug, Subhasree Basu, Fang Wang, Emanuela Ricciotti, Concetta DiRusso, Maureen E. Murphy, Robert H. Vonderheide, Paul M. Lieberman, Charles Mulligan, Brian Nam, Neil Hockstein, Gregory Masters, Michael Guarino, Cindy Lin, Yulia Nefedova, Paul Black, Valerian E. Kagan and Dmitry I. Gabrilovich

Transposon molecular domestication and the evolution of the RAG recombinase pp. 79-84

Yuhang Zhang, Tat Cheung Cheng, Guangrui Huang, Qingyi Lu, Marius D. Surleac, Jeffrey D. Mandell, Pierre Pontarotti, Andrei J. Petrescu, Anlong Xu, Yong Xiong and David G. Schatz

A nearby neutron-star merger explains the actinide abundances in the early Solar System pp. 85-88

Imre Bartos and Szabolcs Marka

Evidence of topological superconductivity in planar Josephson junctions pp. 89-92

Antonio Fornieri, Alexander M. Whiticar, F. Setiawan, Elías Portolés, Asbjørn C. C. Drachmann, Anna Keselman, Sergei Gronin, Candice Thomas, Tian Wang, Ray Kallaher, Geoffrey C. Gardner, Erez Berg, Michael J. Manfra, Ady Stern, Charles M. Marcus and Fabrizio Nichele

Topological superconductivity in a phase-controlled Josephson junction pp. 93-98

Hechen Ren, Falko Pientka, Sean Hart, Andrew T. Pierce, Michael Kosowsky, Lukas Lunczer, Raimund Schlereth, Benedikt Scharf, Ewelina M. Hankiewicz, Laurens W. Molenkamp, Bertrand I. Halperin and Amir Yacoby

High-temperature bulk metallic glasses developed by combinatorial methods pp. 99-103

Ming-Xing Li, Shao-Fan Zhao, Zhen Lu, Akihiko Hirata, Ping Wen, Hai-Yang Bai, MingWei Chen, Jan Schroers, YanHui Liu and Wei-Hua Wang

Synthesis and breakdown of universal metabolic precursors promoted by iron pp. 104-107

Kamila B. Muchowska, Sreejith J. Varma and Joseph Moran

Greater vulnerability to warming of marine versus terrestrial ectotherms pp. 108-111

Malin L. Pinsky, Anne Maria Eikeset, Douglas J. McCauley, Jonathan L. Payne and Jennifer M. Sunday

Phylogenetic evidence for Sino-Tibetan origin in northern China in the Late Neolithic pp. 112-115

Menghan Zhang, Shi Yan, Wuyun Pan and Li Jin

Oxytocin-dependent reopening of a social reward learning critical period with MDMA pp. 116-120

Romain Nardou, Eastman M. Lewis, Rebecca Rothhaas, Ran Xu, Aimei Yang, Edward Boyden and Gül Dölen

Single-cell transcriptomes of the regenerating intestine reveal a revival stem cell pp. 121-125

Arshad Ayyaz, Sandeep Kumar, Bruno Sangiorgi, Bibaswan Ghoshal, Jessica Gosio, Shaida Ouladan, Mardi Fink, Seda Barutcu, Daniel Trcka, Jess Shen, Kin Chan, Jeffrey L. Wrana and Alex Gregorieff

Compartmentalized gut lymph node drainage dictates adaptive immune responses pp. 126-130

Daria Esterházy, Maria C. C. Canesso, Luka Mesin, Paul A. Muller, Tiago B. R. Castro, Ainsley Lockhart, Mahmoud ElJalby, Ana M. C. Faria and Daniel Mucida

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring pp. 131-135

Yu Shi, Weina Gao, Nikki K. Lytle, Peiwu Huang, Xiao Yuan, Amanda M. Dann, Maya Ridinger-Saison, Kathleen E. DelGiorno, Corina E. Antal, Gaoyang Liang, Annette R. Atkins, Galina Erikson, Huaiyu Sun, Jill Meisenhelder, Elena Terenziani, Gyunghwi Woo, Linjing Fang, Thom P. Santisakultarm, Uri Manor, Ruilian Xu, Carlos R. Becerra, Erkut Borazanci, Daniel D. Hoff, Paul M. Grandgenett, Michael A. Hollingsworth, Mathias Leblanc, Sarah E. Umetsu, Eric A. Collisson, Miriam Scadeng, Andrew M. Lowy, Timothy R. Donahue, Tannishtha Reya, Michael Downes, Ronald M. Evans, Geoffrey M. Wahl, Tony Pawson, Ruijun Tian and Tony Hunter

Mammalian ISWI and SWI/SNF selectively mediate binding of distinct transcription factors pp. 136-140

Darko Barisic, Michael B. Stadler, Mario Iurlaro and Dirk Schübeler

Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport pp. 141-145

Jonathan A. Coleman, Dongxue Yang, Zhiyu Zhao, Po-Chao Wen, Craig Yoshioka, Emad Tajkhorshid and Eric Gouaux

Seven ways scientists handle technology challenges in resource-poor settings pp. 147-148

Charles Q. Choi

Why scientist-mums in the United States need better parental-support policies pp. 149-151

Kendall Powell

Without access pp. 154-154

Deborah Walker