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2021, volume 591, articles 7851

Old-growth forest carbon sinks overestimated pp. E21-E23

Per Gundersen, Emil E. Thybring, Thomas Nord-Larsen, Lars Vesterdal, Knute J. Nadelhoffer and Vivian K. Johannsen

Reply to: Old-growth forest carbon sinks overestimated pp. E24-E25

Sebastiaan Luyssaert, E.-Detlef Schulze, Alexander Knohl, Beverly E. Law, Philippe Ciais and John Grace

Author Correction: Sex-specific adipose tissue imprinting of regulatory T cells pp. E26-E26

Ajithkumar Vasanthakumar, David Chisanga, Jonas Blume, Renee Gloury, Kara Britt, Darren C. Henstridge, Yifan Zhan, Santiago Valle Torres, Sebastian Liene, Nicholas Collins, Enyuan Cao, Tom Sidwell, Chaoran Li, Raul German Spallanzani, Yang Liao, Paul A. Beavis, Thomas Gebhardt, Natalie Trevaskis, Stephen L. Nutt, Jeffrey D. Zajac, Rachel A. Davey, Mark A. Febbraio, Diane Mathis, Wei Shi and Axel Kallies

Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes pp. E27-E27

Alexander G. Bick, Joshua S. Weinstock, Satish K. Nandakumar, Charles P. Fulco, Erik L. Bao, Seyedeh M. Zekavat, Mindy D. Szeto, Xiaotian Liao, Matthew J. Leventhal, Joseph Nasser, Kyle Chang, Cecelia Laurie, Bala Bharathi Burugula, Christopher J. Gibson, Abhishek Niroula, Amy E. Lin, Margaret A. Taub, Francois Aguet, Kristin Ardlie, Braxton D. Mitchell, Kathleen C. Barnes, Arden Moscati, Myriam Fornage, Susan Redline, Bruce M. Psaty, Edwin K. Silverman, Scott T. Weiss, Nicholette D. Palmer, Ramachandran S. Vasan, Esteban G. Burchard, Sharon L. R. Kardia, Jiang He, Robert C. Kaplan, Nicholas L. Smith, Donna K. Arnett, David A. Schwartz, Adolfo Correa, Mariza Andrade, Xiuqing Guo, Barbara A. Konkle, Brian Custer, Juan M. Peralta, Hongsheng Gui, Deborah A. Meyers, Stephen T. McGarvey, Ida Yii- Der Chen, M. Benjamin Shoemaker, Patricia A. Peyser, Jai G. Broome, Stephanie M. Gogarten, Fei Fei Wang, Quenna Wong, May E. Montasser, Michelle Daya, Eimear E. Kenny, Kari E. North, Lenore J. Launer, Brian E. Cade, Joshua C. Bis, Michael H. Cho, Jessica Lasky-Su, Donald W. Bowden, L. Adrienne Cupples, Angel C. Y. Mak, Lewis C. Becker, Jennifer A. Smith, Tanika N. Kelly, Stella Aslibekyan, Susan R. Heckbert, Hemant K. Tiwari, Ivana V. Yang, John A. Heit, Steven A. Lubitz, Jill M. Johnsen, Joanne E. Curran, Sally E. Wenzel, Daniel E. Weeks, Dabeeru C. Rao, Dawood Darbar, Jee-Young Moon, Russell P. Tracy, Erin J. Buth, Nicholas Rafaels, Ruth J. F. Loos, Peter Durda, Yongmei Liu, Lifang Hou, Jiwon Lee, Priyadarshini Kachroo, Barry I. Freedman, Daniel Levy, Lawrence F. Bielak, James E. Hixson, James S. Floyd, Eric A. Whitsel, Patrick T. Ellinor, Marguerite R. Irvin, Tasha E. Fingerlin, Laura M. Raffield, Sebastian M. Armasu, Marsha M. Wheeler, Ester C. Sabino, John Blangero, L. Keoki Williams, Bruce D. Levy, Wayne Huey-Herng Sheu, Dan M. Roden, Eric Boerwinkle, JoAnn E. Manson, Rasika A. Mathias, Pinkal Desai, Kent D. Taylor, Andrew D. Johnson, Paul L. Auer, Charles Kooperberg, Cathy C. Laurie, Thomas W. Blackwell, Albert V. Smith, Hongyu Zhao, Ethan Lange, Leslie Lange, Stephen S. Rich, Jerome I. Rotter, James G. Wilson, Paul Scheet, Jacob O. Kitzman, Eric S. Lander, Jesse M. Engreitz, Benjamin L. Ebert, Alexander P. Reiner, Siddhartha Jaiswal, Gonçalo Abecasis, Vijay G. Sankaran, Sekar Kathiresan and Pradeep Natarajan

Author Correction: The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression pp. E28-E28

Lena Seifert, Gregor Werba, Shaun Tiwari, Nancy Ngoc Giao Ly, Sara Alothman, Dalia Alqunaibit, Antonina Avanzi, Rocky Barilla, Donnele Daley, Stephanie H. Greco, Alejandro Torres-Hernandez, Matthew Pergamo, Atsuo Ochi, Constantinos P. Zambirinis, Mridul Pansari, Mauricio Rendon, Daniel Tippens, Mautin Hundeyin, Vishnu R. Mani, Cristina Hajdu, Dannielle Engle and George Miller

Author Correction: Population genomics of the Viking world pp. E29-E29

Ashot Margaryan, Daniel J. Lawson, Martin Sikora, Fernando Racimo, Simon Rasmussen, Ida Moltke, Lara M. Cassidy, Emil Jørsboe, Andrés Ingason, Mikkel W. Pedersen, Thorfinn Korneliussen, Helene Wilhelmson, Magdalena M. Buś, Peter Barros Damgaard, Rui Martiniano, Gabriel Renaud, Claude Bhérer, J. Víctor Moreno-Mayar, Anna K. Fotakis, Marie Allen, Raili Allmäe, Martyna Molak, Enrico Cappellini, Gabriele Scorrano, Hugh McColl, Alexandra Buzhilova, Allison Fox, Anders Albrechtsen, Berit Schütz, Birgitte Skar, Caroline Arcini, Ceri Falys, Charlotte Hedenstierna Jonson, Dariusz Błaszczyk, Denis Pezhemsky, Gordon Turner-Walker, Hildur Gestsdóttir, Inge Lundstrøm, Ingrid Gustin, Ingrid Mainland, Inna Potekhina, Italo M. Muntoni, Jade Cheng, Jesper Stenderup, Jilong Ma, Julie Gibson, Jüri Peets, Jörgen Gustafsson, Katrine H. Iversen, Linzi Simpson, Lisa Strand, Louise Loe, Maeve Sikora, Marek Florek, Maria Vretemark, Mark Redknap, Monika Bajka, Tamara Pushkina, Morten Søvsø, Natalia Grigoreva, Tom Christensen, Ole Kastholm, Otto Uldum, Pasquale Favia, Per Holck, Sabine Sten, Símun V. Arge, Sturla Ellingvåg, Vayacheslav Moiseyev, Wiesław Bogdanowicz, Yvonne Magnusson, Ludovic Orlando, Peter Pentz, Mads Dengsø Jessen, Anne Pedersen, Mark Collard, Daniel G. Bradley, Marie Louise Jørkov, Jette Arneborg, Niels Lynnerup, Neil Price, M. Thomas P. Gilbert, Morten E. Allentoft, Jan Bill, Søren M. Sindbæk, Lotte Hedeager, Kristian Kristiansen, Rasmus Nielsen, Thomas Werge and Eske Willerslev

Retraction Note: Quantized Majorana conductance pp. E30-E30

Hao Zhang, Chun-Xiao Liu, Sasa Gazibegovic, Di Xu, John A. Logan, Guanzhong Wang, Nick Loo, Jouri D. S. Bommer, Michiel W. A. Moor, Diana Car, Roy L. M. Op het Veld, Petrus J. Veldhoven, Sebastian Koelling, Marcel A. Verheijen, Mihir Pendharkar, Daniel J. Pennachio, Borzoyeh Shojaei, Joon Sue Lee, Chris J. Palmstrøm, Erik P. A. M. Bakkers, S. Das Sarma and Leo P. Kouwenhoven

Quantum diamond sensors pp. S37-S37

Neil Savage

How quantum diamonds work: from imaging magnetic fields to detecting viruses pp. S38-S39

Neil Savage

Linguistic tricks to grab your online audience’s attention pp. S41-S42

Valerie Fridland and Ruth Gotian

Raising my hand to ask a question terrifies me, and I am not alone pp. S43-S43

Simon Evans

COVID-19 recovery: science isn’t enough to save us pp. 503-503

Hetan Shah

A month on Mars: what NASA’s Perseverance rover has found so far pp. 509-510

Alexandra Witze

Lab-grown structures mimic human embryo's earliest stage yet pp. 510-511

Nidhi Subbaraman

Has COVID peaked? Maybe, but it’s too soon to be sure pp. 512-513

Smriti Mallapaty

COVID antibody treatments show promise for preventing severe disease pp. 513-514

Heidi Ledford

Mars’s core has been measured — and it’s surprisingly large pp. 514-515

Alexandra Witze

Scientists grew tiny tear glands in a dish — then made them cry pp. 515-515

Heidi Ledford

The fight against fake-paper factories that churn out sham science pp. 516-519

Holly Else and Richard Van Noorden

Five reasons why COVID herd immunity is probably impossible pp. 520-522

Christie Aschwanden

Vera Rubin, astronomer extraordinaire — a new biography pp. 523-524

Alison Abbott

What Newton did next, the power of self-deception, and how the new normal becomes normal: Books in brief pp. 524-524

Andrew Robinson

Form a climate club: United States, European Union and China pp. 526-528

Simone Tagliapietra and Guntram Wolff

Vaccination certificates could entrench inequality pp. 529-529

Françoise Baylis and Natalie Kofler

Genomics data: the broken promise is to Indigenous people pp. 529-529

Krystal S. Tsosie, Keolu Fox and Joseph M. Yracheta

Pool patents to get COVID vaccines and drugs to all pp. 529-529

Etienne Billette de Villemeur, Vianney Dequiedt and Bruno Versaevel

First complete model of the human embryo pp. 531-532

Yi Zheng and Jianping Fu

Effects of rising CO2 levels on carbon sequestration are coordinated above and below ground pp. 532-534

Ana Bastos and Katrin Fleischer

Atomic clocks compared with astounding accuracy pp. 534-535

Rachel M. Godun

Mitochondria are mixed during cell division pp. 535-537

Till Klecker and Benedikt Westermann

Road map for domesticating multi-genome rice using gene editing pp. 537-538

Diane R. Wang

Towards a rigorous understanding of societal responses to climate change pp. 539-550

Dagomar Degroot, Kevin Anchukaitis, Martin Bauch, Jakob Burnham, Fred Carnegy, Jianxin Cui, Kathryn de Luna, Piotr Guzowski, George Hambrecht, Heli Huhtamaa, Adam Izdebski, Katrin Kleemann, Emma Moesswilde, Naresh Neupane, Timothy Newfield, Qing Pei, Elena Xoplaki and Natale Zappia

A 20-year retrospective review of global aquaculture pp. 551-563

Rosamond L. Naylor, Ronald W. Hardy, Alejandro H. Buschmann, Simon R. Bush, Ling Cao, Dane H. Klinger, David C. Little, Jane Lubchenco, Sandra E. Shumway and Max Troell

Nondestructive detection of photonic qubits pp. 570-574

Dominik Niemietz, Pau Farrera, Stefan Langenfeld and Gerhard Rempe

Control and readout of a superconducting qubit using a photonic link pp. 575-579

F. Lecocq, F. Quinlan, K. Cicak, J. Aumentado, S. A. Diddams and J. D. Teufel

A four-qubit germanium quantum processor pp. 580-585

Nico W. Hendrickx, William I. L. Lawrie, Maximilian Russ, Floor Riggelen, Sander L. Snoo, Raymond N. Schouten, Amir Sammak, Giordano Scappucci and Menno Veldhorst

Macroscopic materials assembled from nanoparticle superlattices pp. 586-591

Peter J. Santos, Paul A. Gabrys, Leonardo Z. Zornberg, Margaret S. Lee and Robert J. Macfarlane

Summertime increases in upper-ocean stratification and mixed-layer depth pp. 592-598

Jean-Baptiste Sallée, Violaine Pellichero, Camille Akhoudas, Etienne Pauthenet, Lucie Vignes, Sunke Schmidtko, Alberto Naveira Garabato, Peter Sutherland and Mikael Kuusela

A trade-off between plant and soil carbon storage under elevated CO2 pp. 599-603

C. Terrer, R. P. Phillips, B. A. Hungate, J. Rosende, J. Pett-Ridge, M. E. Craig, K. J. Groenigen, T. F. Keenan, B. N. Sulman, B. D. Stocker, P. B. Reich, A. F. A. Pellegrini, E. Pendall, H. Zhang, R. D. Evans, Y. Carrillo, J. B. Fisher, K. Sundert, Sara Vicca and R. B. Jackson

Decoding and perturbing decision states in real time pp. 604-609

Diogo Peixoto, Jessica R. Verhein, Roozbeh Kiani, Jonathan C. Kao, Paul Nuyujukian, Chandramouli Chandrasekaran, Julian Brown, Sania Fong, Stephen I. Ryu, Krishna V. Shenoy and William T. Newsome

Single-neuronal predictions of others’ beliefs in humans pp. 610-614

Mohsen Jamali, Benjamin L. Grannan, Evelina Fedorenko, Rebecca Saxe, Raymundo Báez-Mendoza and Ziv M. Williams

Reset of hippocampal–prefrontal circuitry facilitates learning pp. 615-619

Alan J. Park, Alexander Z. Harris, Kelly M. Martyniuk, Chia-Yuan Chang, Atheir I. Abbas, Daniel C. Lowes, Christoph Kellendonk, Joseph A. Gogos and Joshua A. Gordon

Blastocyst-like structures generated from human pluripotent stem cells pp. 620-626

Leqian Yu, Yulei Wei, Jialei Duan, Daniel A. Schmitz, Masahiro Sakurai, Lei Wang, Kunhua Wang, Shuhua Zhao, Gary C. Hon and Jun Wu

Modelling human blastocysts by reprogramming fibroblasts into iBlastoids pp. 627-632

Xiaodong Liu, Jia Ping Tan, Jan Schröder, Asma Aberkane, John F. Ouyang, Monika Mohenska, Sue Mei Lim, Yu B. Y. Sun, Joseph Chen, Guizhi Sun, Yichen Zhou, Daniel Poppe, Ryan Lister, Amander T. Clark, Owen J. L. Rackham, Jennifer Zenker and Jose M. Polo

Multi-kingdom ecological drivers of microbiota assembly in preterm infants pp. 633-638

Chitong Rao, Katharine Z. Coyte, Wayne Bainter, Raif S. Geha, Camilia R. Martin and Seth Rakoff-Nahoum

Evolution of antibody immunity to SARS-CoV-2 pp. 639-644

Christian Gaebler, Zijun Wang, Julio C. C. Lorenzi, Frauke Muecksch, Shlomo Finkin, Minami Tokuyama, Alice Cho, Mila Jankovic, Dennis Schaefer-Babajew, Thiago Y. Oliveira, Melissa Cipolla, Charlotte Viant, Christopher O. Barnes, Yaron Bram, Gaëlle Breton, Thomas Hägglöf, Pilar Mendoza, Arlene Hurley, Martina Turroja, Kristie Gordon, Katrina G. Millard, Victor Ramos, Fabian Schmidt, Yiska Weisblum, Divya Jha, Michael Tankelevich, Gustavo Martinez-Delgado, Jim Yee, Roshni Patel, Juan Dizon, Cecille Unson-O’Brien, Irina Shimeliovich, Davide F. Robbiani, Zhen Zhao, Anna Gazumyan, Robert E. Schwartz, Theodora Hatziioannou, Pamela J. Bjorkman, Saurabh Mehandru, Paul D. Bieniasz, Marina Caskey and Michel C. Nussenzweig

Metabolic support of tumour-infiltrating regulatory T cells by lactic acid pp. 645-651

McLane J. Watson, Paolo D. A. Vignali, Steven J. Mullett, Abigail E. Overacre-Delgoffe, Ronal M. Peralta, Stephanie Grebinoski, Ashley V. Menk, Natalie L. Rittenhouse, Kristin DePeaux, Ryan D. Whetstone, Dario A. A. Vignali, Timothy W. Hand, Amanda C. Poholek, Brett M. Morrison, Jeffrey D. Rothstein, Stacy G. Wendell and Greg M. Delgoffe

CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumours pp. 652-658

Roberta Zappasodi, Inna Serganova, Ivan J. Cohen, Masatomo Maeda, Masahiro Shindo, Yasin Senbabaoglu, McLane J. Watson, Avigdor Leftin, Rachana Maniyar, Svena Verma, Matthew Lubin, Myat Ko, Mayuresh M. Mane, Hong Zhong, Cailian Liu, Arnab Ghosh, Mohsen Abu-Akeel, Ellen Ackerstaff, Jason A. Koutcher, Ping-Chih Ho, Greg M. Delgoffe, Ronald Blasberg, Jedd D. Wolchok and Taha Merghoub

Actin cables and comet tails organize mitochondrial networks in mitosis pp. 659-664

Andrew S. Moore, Stephen M. Coscia, Cory L. Simpson, Fabian E. Ortega, Eric C. Wait, John M. Heddleston, Jeffrey J. Nirschl, Christopher J. Obara, Pedro Guedes-Dias, C. Alexander Boecker, Teng-Leong Chew, Julie A. Theriot, Jennifer Lippincott-Schwartz and Erika L. F. Holzbaur

BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52 pp. 665-670

Elodie Hatchi, Liana Goehring, Serena Landini, Konstantina Skourti-Stathaki, Derrick K. DeConti, Fieda O. Abderazzaq, Priyankana Banerjee, Timothy M. Demers, Yaoyu E. Wang, John Quackenbush and David M. Livingston

Centromeres are dismantled by foundational meiotic proteins Spo11 and Rec8 pp. 671-676

Haitong Hou, Eftychia Kyriacou, Rahul Thadani, Michael Klutstein, Joseph H. Chapman and Julia Promisel Cooper

Structural insights into the inhibition of glycine reuptake pp. 677-681

Azadeh Shahsavar, Peter Stohler, Gleb Bourenkov, Iwan Zimmermann, Martin Siegrist, Wolfgang Guba, Emmanuel Pinard, Steffen Sinning, Markus A. Seeger, Thomas R. Schneider, Roger J. P. Dawson and Poul Nissen

‘A lot of room for bias’: UK funder’s data point to uneven playing field pp. 683-684

Chris Woolston

Electronic skin: from flexibility to a sense of touch pp. 685-687

Katharine Sanderson

Engineering a brighter future for refugees and female scientists in Uganda pp. 690-690

Sara Moraca

2021, volume 591, articles 7850

Rising tide of China’s science lifts Asia-Pacific research pp. S5-S5

Catherine Armitage

Politics and the pandemic disrupt migration patterns in research pp. S6-S9

Catherine Armitage

COVID-19 acts as a catalyst in India’s quest for self-sufficiency pp. S15-S15

Priyanka Pulla

Author Correction: Design of biologically active binary protein 2D materials pp. E16-E16

Ariel J. Ben-Sasson, Joseph L. Watson, William Sheffler, Matthew Camp Johnson, Alice Bittleston, Logeshwaran Somasundaram, Justin Decarreau, Fang Jiao, Jiajun Chen, Ioanna Mela, Andrew A. Drabek, Sanchez M. Jarrett, Stephen C. Blacklow, Clemens F. Kaminski, Greg L. Hura, James J. Yoreo, Justin M. Kollman, Hannele Ruohola-Baker, Emmanuel Derivery and David Baker

Author Correction: Landau quantization and highly mobile fermions in an insulator pp. E17-E17

Pengjie Wang, Guo Yu, Yanyu Jia, Michael Onyszczak, F. Alexandre Cevallos, Shiming Lei, Sebastian Klemenz, Kenji Watanabe, Takashi Taniguchi, Robert J. Cava, Leslie M. Schoop and Sanfeng Wu

Publisher Correction: Measuring the α-particle charge radius with muonic helium-4 ions pp. E18-E18

Julian J. Krauth, Karsten Schuhmann, Marwan Abdou Ahmed, Fernando D. Amaro, Pedro Amaro, François Biraben, Tzu-Ling Chen, Daniel S. Covita, Andreas J. Dax, Marc Diepold, Luis M. P. Fernandes, Beatrice Franke, Sandrine Galtier, Andrea L. Gouvea, Johannes Götzfried, Thomas Graf, Theodor W. Hänsch, Jens Hartmann, Malte Hildebrandt, Paul Indelicato, Lucile Julien, Klaus Kirch, Andreas Knecht, Yi-Wei Liu, Jorge Machado, Cristina M. B. Monteiro, Françoise Mulhauser, Boris Naar, Tobias Nebel, François Nez, Joaquim M. F. Santos, José Paulo Santos, Csilla I. Szabo, David Taqqu, João F. C. A. Veloso, Jan Vogelsang, Andreas Voss, Birgit Weichelt, Randolf Pohl, Aldo Antognini and Franz Kottmann

Publisher Correction: Chromothripsis drives the evolution of gene amplification in cancer pp. E19-E19

Ofer Shoshani, Simon F. Brunner, Rona Yaeger, Peter Ly, Yael Nechemia-Arbely, Dong Hyun Kim, Rongxin Fang, Guillaume A. Castillon, Miao Yu, Julia S. Z. Li, Ying Sun, Mark H. Ellisman, Bing Ren, Peter J. Campbell and Don W. Cleveland

Publisher Correction: Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency pp. E20-E20

Parinaz Mehdipour, Sajid A. Marhon, Ilias Ettayebi, Ankur Chakravarthy, Amir Hosseini, Yadong Wang, Fabíola Attié Castro, Helen Loo Yau, Charles Ishak, Sagi Abelson, Catherine A. O’Brien and Daniel D. De Carvalho

Japan and South Korea pursue shared interests pp. S24-S25

Ichiko Fuyuno

Southeast Asian countries join forces for scientific strength pp. S30-S32

Sandy Ong

To quell misinformation, use carrots — not just sticks pp. 347-347

Tali Sharot

China’s five-year plan focuses on scientific self-reliance pp. 353-354

Smriti Mallapaty

Evidence of elusive Majorana particle dies — but computing hope lives on pp. 354-355

Davide Castelvecchi

US health agency will invest $1 billion to investigate ‘long COVID’ pp. 356-356

Nidhi Subbaraman

Achilles heel spotted for promising HIV-prevention drug pp. 357-358

Amy Maxmen

Record number of asteroids seen whizzing past Earth in 2020 pp. 358-358

Alexandra Witze

CRISPR-based gene therapy dampens pain in mice pp. 359-359

Ariana Remmel

How microbes in permafrost could trigger a massive carbon bomb pp. 360-362

Monique Brouillette

A tour of deep time brings comfort in hard times pp. 363-364

Alexandra Witze

The accidental Nobel laureate, what we owe to our voices and the philosophy of touch: Books in Brief pp. 364-364

Andrew Robinson

Net-zero emissions targets are vague: three ways to fix pp. 365-368

Joeri Rogelj, Oliver Geden, Annette Cowie and Andy Reisinger

Brazil: Boost COVID-19 vaccine uptake in Indigenous people pp. 369-369

Eliel Benites, Laura Jane Gisloti and Fabio de Oliveira Roque

Vaccinate in biodiversity hotspots to protect people and wildlife from each other pp. 369-369

Fabian H. Leendertz and Gladys Kalema-Zikusoka

End the neglect of Black patients in US health care pp. 369-369

Eseosa Ighodaro and Andrew Spector

Mechanical effects on the genome known since 1948 pp. 369-369

Brian Freeman

Exercise generates immune cells in bone pp. 371-372

Mehmet Saçma and Hartmut Geiger

Breaks in mitochondrial DNA rig the immune response pp. 372-373

Nandhitha Uma Naresh and Cole M. Haynes

Argument technology for debating with humans pp. 373-374

Chris Reed

A microbial marriage reminiscent of mitochondrial evolution pp. 375-376

William H. Lewis and Thijs J. G. Ettema

Oceanic fault zones reconstructed pp. 376-377

Garrett Ito

An autonomous debating system pp. 379-384

Noam Slonim, Yonatan Bilu, Carlos Alzate, Roy Bar-Haim, Ben Bogin, Francesca Bonin, Leshem Choshen, Edo Cohen-Karlik, Lena Dankin, Lilach Edelstein, Liat Ein-Dor, Roni Friedman-Melamed, Assaf Gavron, Ariel Gera, Martin Gleize, Shai Gretz, Dan Gutfreund, Alon Halfon, Daniel Hershcovich, Ron Hoory, Yufang Hou, Shay Hummel, Michal Jacovi, Charles Jochim, Yoav Kantor, Yoav Katz, David Konopnicki, Zvi Kons, Lili Kotlerman, Dalia Krieger, Dan Lahav, Tamar Lavee, Ran Levy, Naftali Liberman, Yosi Mass, Amir Menczel, Shachar Mirkin, Guy Moshkowich, Shila Ofek-Koifman, Matan Orbach, Ella Rabinovich, Ruty Rinott, Slava Shechtman, Dafna Sheinwald, Eyal Shnarch, Ilya Shnayderman, Aya Soffer, Artem Spector, Benjamin Sznajder, Assaf Toledo, Orith Toledo-Ronen, Elad Venezian and Ranit Aharonov

High-order superlattices by rolling up van der Waals heterostructures pp. 385-390

Bei Zhao, Zhong Wan, Yuan Liu, Junqing Xu, Xiangdong Yang, Dingyi Shen, Zucheng Zhang, Chunhao Guo, Qi Qian, Jia Li, Ruixia Wu, Zhaoyang Lin, Xingxu Yan, Bailing Li, Zhengwei Zhang, Huifang Ma, Bo Li, Xiao Chen, Yi Qiao, Imran Shakir, Zeyad Almutairi, Fei Wei, Yue Zhang, Xiaoqing Pan, Yu Huang, Yuan Ping, Xidong Duan and Xiangfeng Duan

Widespread potential loss of streamflow into underlying aquifers across the USA pp. 391-395

Scott Jasechko, Hansjörg Seybold, Debra Perrone, Ying Fan and James W. Kirchner

Enabling conditions for an equitable and sustainable blue economy pp. 396-401

Andrés M. Cisneros-Montemayor, Marcia Moreno-Báez, Gabriel Reygondeau, William W. L. Cheung, Katherine M. Crosman, Pedro C. González-Espinosa, Vicky W. Y. Lam, Muhammed A. Oyinlola, Gerald G. Singh, Wilf Swartz, Chong-wei Zheng and Yoshitaka Ota

Extensional tectonics and two-stage crustal accretion at oceanic transform faults pp. 402-407

Ingo Grevemeyer, Lars H. Rüpke, Jason P. Morgan, Karthik Iyer and Colin W. Devey

Non-ammocoete larvae of Palaeozoic stem lampreys pp. 408-412

Tetsuto Miyashita, Robert W. Gess, Kristen Tietjen and Michael I. Coates

Genomic insights into the formation of human populations in East Asia pp. 413-419

Chuan-Chao Wang, Hui-Yuan Yeh, Alexander N. Popov, Hu-Qin Zhang, Hirofumi Matsumura, Kendra Sirak, Olivia Cheronet, Alexey Kovalev, Nadin Rohland, Alexander M. Kim, Swapan Mallick, Rebecca Bernardos, Dashtseveg Tumen, Jing Zhao, Yi-Chang Liu, Jiun-Yu Liu, Matthew Mah, Ke Wang, Zhao Zhang, Nicole Adamski, Nasreen Broomandkhoshbacht, Kimberly Callan, Francesca Candilio, Kellie Sara Duffett Carlson, Brendan J. Culleton, Laurie Eccles, Suzanne Freilich, Denise Keating, Ann Marie Lawson, Kirsten Mandl, Megan Michel, Jonas Oppenheimer, Kadir Toykan Özdoğan, Kristin Stewardson, Shaoqing Wen, Shi Yan, Fatma Zalzala, Richard Chuang, Ching-Jung Huang, Hana Looh, Chung-Ching Shiung, Yuri G. Nikitin, Andrei V. Tabarev, Alexey A. Tishkin, Song Lin, Zhou-Yong Sun, Xiao-Ming Wu, Tie-Lin Yang, Xi Hu, Liang Chen, Hua Du, Jamsranjav Bayarsaikhan, Enkhbayar Mijiddorj, Diimaajav Erdenebaatar, Tumur-Ochir Iderkhangai, Erdene Myagmar, Hideaki Kanzawa-Kiriyama, Masato Nishino, Ken-ichi Shinoda, Olga A. Shubina, Jianxin Guo, Wangwei Cai, Qiongying Deng, Longli Kang, Dawei Li, Dongna Li, Rong Lin, Nini, Rukesh Shrestha, Ling-Xiang Wang, Lanhai Wei, Guangmao Xie, Hongbing Yao, Manfei Zhang, Guanglin He, Xiaomin Yang, Rong Hu, Martine Robbeets, Stephan Schiffels, Douglas J. Kennett, Li Jin, Hui Li, Johannes Krause, Ron Pinhasi and David Reich

Striatal activity topographically reflects cortical activity pp. 420-425

Andrew J. Peters, Julie M. J. Fabre, Nicholas A. Steinmetz, Kenneth D. Harris and Matteo Carandini

Dopamine-based mechanism for transient forgetting pp. 426-430

John Martin Sabandal, Jacob A. Berry and Ronald L. Davis

A growth-factor-activated lysosomal K+ channel regulates Parkinson’s pathology pp. 431-437

Jinhong Wie, Zhenjiang Liu, Haikun Song, Thomas F. Tropea, Lu Yang, Huanhuan Wang, Yuling Liang, Chunlei Cang, Kimberly Aranda, Joey Lohmann, Jing Yang, Boxun Lu, Alice S. Chen-Plotkin, Kelvin C. Luk and Dejian Ren

A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis pp. 438-444

Bo Shen, Alpaslan Tasdogan, Jessalyn M. Ubellacker, Jingzhu Zhang, Elena D. Nosyreva, Liming Du, Malea M. Murphy, Shuiqing Hu, Yating Yi, Nergis Kara, Xin Liu, Shay Guela, Yuemeng Jia, Vijayashree Ramesh, Claire Embree, Evann C. Mitchell, Yunduo C. Zhao, Lining A. Ju, Zhao Hu, Genevieve M. Crane, Zhiyu Zhao, Ruhma Syeda and Sean J. Morrison

Anaerobic endosymbiont generates energy for ciliate host by denitrification pp. 445-450

Jon S. Graf, Sina Schorn, Katharina Kitzinger, Soeren Ahmerkamp, Christian Woehle, Bruno Huettel, Carsten J. Schubert, Marcel M. M. Kuypers and Jana Milucka

SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801 pp. 451-457

Angela Wahl, Lisa E. Gralinski, Claire E. Johnson, Wenbo Yao, Martina Kovarova, Kenneth H. Dinnon, Hongwei Liu, Victoria J. Madden, Halina M. Krzystek, Chandrav De, Kristen K. White, Kendra Gully, Alexandra Schäfer, Tanzila Zaman, Sarah R. Leist, Paul O. Grant, Gregory R. Bluemling, Alexander A. Kolykhalov, Michael G. Natchus, Frederic B. Askin, George Painter, Edward P. Browne, Corbin D. Jones, Raymond J. Pickles, Ralph S. Baric and J. Victor Garcia

Dynamic regulation of TFH selection during the germinal centre reaction pp. 458-463

Julia Merkenschlager, Shlomo Finkin, Victor Ramos, Julian Kraft, Melissa Cipolla, Carla R. Nowosad, Harald Hartweger, Wenzhu Zhang, Paul Dominic B. Olinares, Anna Gazumyan, Thiago Y. Oliveira, Brian T. Chait and Michel C. Nussenzweig

IgA transcytosis and antigen recognition govern ovarian cancer immunity pp. 464-470

Subir Biswas, Gunjan Mandal, Kyle K. Payne, Carmen M. Anadon, Chandler D. Gatenbee, Ricardo A. Chaurio, Tara Lee Costich, Carlos Moran, Carly M. Harro, Kristen E. Rigolizzo, Jessica A. Mine, Jimena Trillo-Tinoco, Naoko Sasamoto, Kathryn L. Terry, Douglas Marchion, Andrea Buras, Robert M. Wenham, Xiaoqing Yu, Mary K. Townsend, Shelley S. Tworoger, Paulo C. Rodriguez, Alexander R. Anderson and Jose R. Conejo-Garcia

Sulfur sequestration promotes multicellularity during nutrient limitation pp. 471-476

Beth Kelly, Gustavo E. Carrizo, Joy Edwards-Hicks, David E. Sanin, Michal A. Stanczak, Chantal Priesnitz, Lea J. Flachsmann, Jonathan D. Curtis, Gerhard Mittler, Yaarub Musa, Thomas Becker, Joerg M. Buescher and Erika L. Pearce

Nuclear sensing of breaks in mitochondrial DNA enhances immune surveillance pp. 477-481

Marco Tigano, Danielle C. Vargas, Samuel Tremblay-Belzile, Yi Fu and Agnel Sfeir

De novo design of modular and tunable protein biosensors pp. 482-487

Alfredo Quijano-Rubio, Hsien-Wei Yeh, Jooyoung Park, Hansol Lee, Robert A. Langan, Scott E. Boyken, Marc J. Lajoie, Longxing Cao, Cameron M. Chow, Marcos C. Miranda, Jimin Wi, Hyo Jeong Hong, Lance Stewart, Byung-Ha Oh and David Baker

Pandemic burnout is rampant in academia pp. 489-491

Virginia Gewin

Unpicking the rhythms of the Amazon rainforest pp. 494-494

Chris Woolston

2021, volume 591, articles 7849

Biodiversity’s importance is growing in China’s urban agenda pp. S1-S3

Sarah O’Meara

Seeing biodiversity from a Chinese perspective pp. S3-S3

Sarah O’Meara

Publisher Correction: Parallel convolutional processing using an integrated photonic tensor core pp. E13-E13

J. Feldmann, N. Youngblood, M. Karpov, H. Gehring, X. Li, M. Stappers, M. Gallo, X. Fu, A. Lukashchuk, A. S. Raja, J. Liu, C. D. Wright, A. Sebastian, T. J. Kippenberg, W. H. P. Pernice and H. Bhaskaran

Addendum: Butterfly effect and a self-modulating El Niño response to global warming pp. E14-E15

Wenju Cai, Benjamin Ng, Tao Geng, Lixin Wu, Agus Santoso and Michael J. McPhaden

COVID vaccination studies: plan now to pool data, or be bogged down in confusion pp. 179-179

Natalie Dean

Scientists want virtual meetings to stay after the COVID pandemic pp. 185-186

Ariana Remmel

Major physics society won’t meet in cities with racist policing record pp. 187-187

Nidhi Subbaraman

Where did COVID come from? Five mysteries that remain pp. 188-189

Smriti Mallapaty

Which are the best pandemic policies? Data trackers are trying to judge pp. 189-189

Quirin Schiermeier

Multitude of coronavirus variants found in the US — but the threat is unclear pp. 190-190

Ewen Callaway

Taiwan fines researcher for allegedly managing projects on Chinese mainland pp. 192-192

Andrew Silver

Pregnancy and COVID: what the data say pp. 193-195

Nidhi Subbaraman

A biographer and a bioethicist take on the CRISPR revolution pp. 196-197

Jackie Leach Scully

Nuclear energy, ten years after Fukushima pp. 199-201

Aditi Verma, Ali Ahmad and Francesca Giovannini

Share pandemic sequences openly and fast pp. 202-202

David Haussler, Max Haeussler, Angie Hinrichs, Russell Corbett-Detig and Isabel Bjork

Sequence data: expand comprehensive access pp. 202-202

Richard J. Roberts

COVID-19: use intersectional analyses to close gaps in outcomes and vaccination pp. 202-202

Janna R. Shapiro, Sabra L. Klein and Rosemary Morgan

Russia: scientists petition to end political persecution pp. 202-202

Alexander Kabanov, Alex Krasnok and Denis Seletskiy

A bird’s migration decoded pp. 203-204

Simeon Lisovski and Miriam Liedvogel

Cancer aided by greasy traitors pp. 204-206

Caroline Perry and Ulf H. Beier

Giant ice cube hints at the existence of cosmic antineutrinos pp. 206-207

Carla Distefano

Million-year-old DNA provides a glimpse of mammoth evolution pp. 208-209

Alfred L. Roca

Ultra-weak gravitational field detected pp. 209-210

Christian Rothleitner

Improving reporting standards for polygenic scores in risk prediction studies pp. 211-219

Hannah Wand, Samuel A. Lambert, Cecelia Tamburro, Michael A. Iacocca, Jack W. O’Sullivan, Catherine Sillari, Iftikhar J. Kullo, Robb Rowley, Jacqueline S. Dron, Deanna Brockman, Eric Venner, Mark I. McCarthy, Antonis C. Antoniou, Douglas F. Easton, Robert A. Hegele, Amit V. Khera, Nilanjan Chatterjee, Charles Kooperberg, Karen Edwards, Katherine Vlessis, Kim Kinnear, John N. Danesh, Helen Parkinson, Erin M. Ramos, Megan C. Roberts, Kelly E. Ormond, Muin J. Khoury, A. Cecile J. W. Janssens, Katrina A. B. Goddard, Peter Kraft, Jaqueline A. L. MacArthur, Michael Inouye and Genevieve L. Wojcik

Measurement of gravitational coupling between millimetre-sized masses pp. 225-228

Tobias Westphal, Hans Hepach, Jeremias Pfaff and Markus Aspelmeyer

Experimental quantum speed-up in reinforcement learning agents pp. 229-233

V. Saggio, B. E. Asenbeck, A. Hamann, T. Strömberg, P. Schiansky, V. Dunjko, N. Friis, N. C. Harris, M. Hochberg, D. Englund, S. Wölk, H. J. Briegel and P. Walther

Towards real-time photorealistic 3D holography with deep neural networks pp. 234-239

Liang Shi, Beichen Li, Changil Kim, Petr Kellnhofer and Wojciech Matusik

Large-area display textiles integrated with functional systems pp. 240-245

Xiang Shi, Yong Zuo, Peng Zhai, Jiahao Shen, Yangyiwei Yang, Zhen Gao, Meng Liao, Jingxia Wu, Jiawei Wang, Xiaojie Xu, Qi Tong, Bo Zhang, Bingjie Wang, Xuemei Sun, Lihua Zhang, Qibing Pei, Dayong Jin, Peining Chen and Huisheng Peng

Thermal-expansion offset for high-performance fuel cell cathodes pp. 246-251

Yuan Zhang, Bin Chen, Daqin Guan, Meigui Xu, Ran Ran, Meng Ni, Wei Zhou, Ryan O’Hayre and Zongping Shao

Propagation of large earthquakes as self-healing pulses or mild cracks pp. 252-258

Valère Lambert, Nadia Lapusta and Stephen Perry

Climate-driven flyway changes and memory-based long-distance migration pp. 259-264

Zhongru Gu, Shengkai Pan, Zhenzhen Lin, Li Hu, Xiaoyang Dai, Jiang Chang, Yuanchao Xue, Han Su, Juan Long, Mengru Sun, Sergey Ganusevich, Vasiliy Sokolov, Aleksandr Sokolov, Ivan Pokrovsky, Fen Ji, Michael W. Bruford, Andrew Dixon and Xiangjiang Zhan

Million-year-old DNA sheds light on the genomic history of mammoths pp. 265-269

Tom van der Valk, Patrícia Pečnerová, David Díez-del-Molino, Anders Bergström, Jonas Oppenheimer, Stefanie Hartmann, Georgios Xenikoudakis, Jessica A. Thomas, Marianne Dehasque, Ekin Sağlıcan, Fatma Rabia Fidan, Ian Barnes, Shanlin Liu, Mehmet Somel, Peter D. Heintzman, Pavel Nikolskiy, Beth Shapiro, Pontus Skoglund, Michael Hofreiter, Adrian M. Lister, Anders Götherström and Love Dalén

Activation and disruption of a neural mechanism for novel choice in monkeys pp. 270-274

Alessandro Bongioanni, Davide Folloni, Lennart Verhagen, Jérôme Sallet, Miriam C. Klein-Flügge and Matthew F. S. Rushworth

STING controls nociception via type I interferon signalling in sensory neurons pp. 275-280

Christopher R. Donnelly, Changyu Jiang, Amanda S. Andriessen, Kaiyuan Wang, Zilong Wang, Huiping Ding, Junli Zhao, Xin Luo, Michael S. Lee, Yu L. Lei, William Maixner, Mei-Chuan Ko and Ru-Rong Ji

Macrophages provide a transient muscle stem cell niche via NAMPT secretion pp. 281-287

Dhanushika Ratnayake, Phong D. Nguyen, Fernando J. Rossello, Verena C. Wimmer, Jean L. Tan, Laura A. Galvis, Ziad Julier, Alasdair J. Wood, Thomas Boudier, Abdulsalam I. Isiaku, Silke Berger, Viola Oorschot, Carmen Sonntag, Kelly L. Rogers, Christophe Marcelle, Graham J. Lieschke, Mikaël M. Martino, Jeroen Bakkers and Peter D. Currie

The TOR–EIN2 axis mediates nuclear signalling to modulate plant growth pp. 288-292

Liwen Fu, Yanlin Liu, Guochen Qin, Ping Wu, Hailing Zi, Zhongtian Xu, Xiaodi Zhao, Yue Wang, Yaxing Li, Shuhui Yang, Chao Peng, Catherine C. L. Wong, Sang-Dong Yoo, Zecheng Zuo, Renyi Liu, Young-Hee Cho and Yan Xiong

Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis pp. 293-299

Bryan A. Johnson, Xuping Xie, Adam L. Bailey, Birte Kalveram, Kumari G. Lokugamage, Antonio Muruato, Jing Zou, Xianwen Zhang, Terry Juelich, Jennifer K. Smith, Lihong Zhang, Nathen Bopp, Craig Schindewolf, Michelle Vu, Abigail Vanderheiden, Emma S. Winkler, Daniele Swetnam, Jessica A. Plante, Patricia Aguilar, Kenneth S. Plante, Vsevolod Popov, Benhur Lee, Scott C. Weaver, Mehul S. Suthar, Andrew L. Routh, Ping Ren, Zhiqiang Ku, Zhiqiang An, Kari Debbink, Michael S. Diamond, Pei-Yong Shi, Alexander N. Freiberg and Vineet D. Menachery

AIM2 in regulatory T cells restrains autoimmune diseases pp. 300-305

Wei-Chun Chou, Zengli Guo, Hao Guo, Liang Chen, Ge Zhang, Kaixin Liang, Ling Xie, Xianming Tan, Sara A. Gibson, Elena Rampanelli, Yan Wang, Stephanie A. Montgomery, W. June Brickey, Meng Deng, Leslie Freeman, Song Zhang, Maureen A. Su, Xian Chen, Yisong Y. Wan and Jenny P.-Y. Ting

Lipid signalling enforces functional specialization of Treg cells in tumours pp. 306-311

Seon Ah Lim, Jun Wei, Thanh-Long M. Nguyen, Hao Shi, Wei Su, Gustavo Palacios, Yogesh Dhungana, Nicole M. Chapman, Lingyun Long, Jordy Saravia, Peter Vogel and Hongbo Chi

m6A RNA methylation regulates the fate of endogenous retroviruses pp. 312-316

Tomasz Chelmicki, Emeline Roger, Aurélie Teissandier, Mathilde Dura, Lorraine Bonneville, Sofia Rucli, François Dossin, Camille Fouassier, Sonia Lameiras and Deborah Bourc’his

METTL3 regulates heterochromatin in mouse embryonic stem cells pp. 317-321

Wenqi Xu, Jiahui Li, Chenxi He, Jing Wen, Honghui Ma, Bowen Rong, Jianbo Diao, Liyong Wang, Jiahua Wang, Feizhen Wu, Li Tan, Yujiang Geno Shi, Yang Shi and Hongjie Shen

The RNA m6A reader YTHDC1 silences retrotransposons and guards ES cell identity pp. 322-326

Jiadong Liu, Mingwei Gao, Jiangping He, Kaixin Wu, Siyuan Lin, Lingmei Jin, Yaping Chen, He Liu, Junjie Shi, Xiwei Wang, Lei Chang, Yingying Lin, Yu-Li Zhao, Xiaofei Zhang, Man Zhang, Guan-Zheng Luo, Guangming Wu, Duanqing Pei, Jie Wang, Xichen Bao and Jiekai Chen

Glutamate transporters have a chloride channel with two hydrophobic gates pp. 327-331

Ichia Chen, Shashank Pant, Qianyi Wu, Rosemary J. Cater, Meghna Sobti, Robert J. Vandenberg, Alastair G. Stewart, Emad Tajkhorshid, Josep Font and Renae M. Ryan

‘Elite’ researchers dominate citation space pp. 333-334

Sara Reardon

Breaking the binary by coming out as a trans scientist pp. 334-335

Robin Aguilar

Tackling the number-one killer in my community pp. 338-338

Amber Dance

2021, volume 591, articles 7848

Hippo signalling maintains ER expression and ER+ breast cancer growth pp. E1-E10

Shenghong Ma, Zhengming Wu, Feng Yang, Jianmin Zhang, Randy L. Johnson, Michael G. Rosenfeld and Kun-Liang Guan

To keep nationalism in check, nurture science solidarity pp. 9-9

Joy Y. Zhang

Reply to: Hippo signalling maintains ER expression and ER+ breast cancer growth pp. E11-E12

Adrian Britschgi, Joana Pinto Couto and Mohamed Bentires-Alj

Fuel for world’s largest fusion reactor ITER is set for test run pp. 15-16

Elizabeth Gibney

Why COVID vaccines are so difficult to compare pp. 16-17

Heidi Ledford

Contact-tracing apps help reduce COVID infections, data suggest pp. 18-19

Dyani Lewis

Can COVID spread from frozen wildlife? Scientists probe pandemic origins pp. 18-19

Dyani Lewis

How Europe’s €100-billion science fund will shape 7 years of research pp. 20-21

Quirin Schiermeier

Robo-writers: the rise and risks of language-generating AI pp. 22-25

Matthew Hutson

The search for animals harbouring coronavirus — and why it matters pp. 26-28

Smriti Mallapaty

Paul J. Crutzen (1933–2021) pp. 29-29

Jos Lelieveld

Want to track pandemic variants faster? Fix the bioinformatics bottleneck pp. 30-33

Emma B. Hodcroft, Nicola De Maio, Rob Lanfear, Duncan R. MacCannell, Bui Quang Minh, Heiko A. Schmidt, Alexandros Stamatakis, Nick Goldman and Christophe Dessimoz

Enforce ban on plastic exports or it could backfire pp. 34-34

Tanveer M. Adyel

Pandemic: public feeling more positive about science pp. 34-34

Eric Allen Jensen, Eric B. Kennedy and Ethan Greenwood

‘Climate neutral’ is a lie — abandon it as a goal pp. 34-34

Claudia Kemfert

Disabled scientists’ networks call for more support pp. 34-34

Maria Niedernhuber, Hamied Haroon and Nicole Brown

Soft robot reaches the deepest part of the ocean pp. 35-36

Cecilia Laschi and Marcello Calisti

Active membrane rupture spurs a range of cell deaths pp. 36-37

Sebastian Hiller and Petr Broz

Some antibodies can dampen antiviral defences in people with severe COVID pp. 37-39

Matteo Gentili and Nir Hacohen

Dynamics of RNA–protein interactions studied in living cells pp. 39-40

Olivia S. Rissland

Photonic chip brings optical quantum computers a step closer pp. 40-41

Ulrik L. Andersen

Promises and prospects of two-dimensional transistors pp. 43-53

Yuan Liu, Xidong Duan, Hyeon-Jin Shin, Seongjun Park, Yu Huang and Xiangfeng Duan

Quantum circuits with many photons on a programmable nanophotonic chip pp. 54-60

J. M. Arrazola, V. Bergholm, K. Brádler, T. R. Bromley, M. J. Collins, I. Dhand, A. Fumagalli, T. Gerrits, A. Goussev, L. G. Helt, J. Hundal, T. Isacsson, R. B. Israel, J. Izaac, S. Jahangiri, R. Janik, N. Killoran, S. P. Kumar, J. Lavoie, A. E. Lita, D. H. Mahler, M. Menotti, B. Morrison, S. W. Nam, L. Neuhaus, H. Y. Qi, N. Quesada, A. Repingon, K. K. Sabapathy, M. Schuld, D. Su, J. Swinarton, A. Száva, K. Tan, P. Tan, V. D. Vaidya, Z. Vernon, Z. Zabaneh and Y. Zhang

Van der Waals heterostructure polaritons with moiré-induced nonlinearity pp. 61-65

Long Zhang, Fengcheng Wu, Shaocong Hou, Zhe Zhang, Yu-Hsun Chou, Kenji Watanabe, Takashi Taniguchi, Stephen R. Forrest and Hui Deng

Self-powered soft robot in the Mariana Trench pp. 66-71

Guorui Li, Xiangping Chen, Fanghao Zhou, Yiming Liang, Youhua Xiao, Xunuo Cao, Zhen Zhang, Mingqi Zhang, Baosheng Wu, Shunyu Yin, Yi Xu, Hongbo Fan, Zheng Chen, Wei Song, Wenjing Yang, Binbin Pan, Jiaoyi Hou, Weifeng Zou, Shunping He, Xuxu Yang, Guoyong Mao, Zheng Jia, Haofei Zhou, Tiefeng Li, Shaoxing Qu, Zhongbin Xu, Zhilong Huang, Yingwu Luo, Tao Xie, Jason Gu, Shiqiang Zhu and Wei Yang

Ligand-engineered bandgap stability in mixed-halide perovskite LEDs pp. 72-77

Yasser Hassan, Jong Hyun Park, Michael L. Crawford, Aditya Sadhanala, Jeongjae Lee, James C. Sadighian, Edoardo Mosconi, Ravichandran Shivanna, Eros Radicchi, Mingyu Jeong, Changduk Yang, Hyosung Choi, Sung Heum Park, Myoung Hoon Song, Filippo Angelis, Cathy Y. Wong, Richard H. Friend, Bo Ram Lee and Henry J. Snaith

Human alteration of global surface water storage variability pp. 78-81

Sarah W. Cooley, Jonathan C. Ryan and Laurence C. Smith

Stress-induced amorphization triggers deformation in the lithospheric mantle pp. 82-86

Vahid Samae, Patrick Cordier, Sylvie Demouchy, Caroline Bollinger, Julien Gasc, Sanae Koizumi, Alexandre Mussi, Dominique Schryvers and Hosni Idrissi

Dire wolves were the last of an ancient New World canid lineage pp. 87-91

Angela R. Perri, Kieren J. Mitchell, Alice Mouton, Sandra Álvarez-Carretero, Ardern Hulme-Beaman, James Haile, Alexandra Jamieson, Julie Meachen, Audrey T. Lin, Blaine W. Schubert, Carly Ameen, Ekaterina E. Antipina, Pere Bover, Selina Brace, Alberto Carmagnini, Christian Carøe, Jose A. Samaniego Castruita, James C. Chatters, Keith Dobney, Mario Reis, Allowen Evin, Philippe Gaubert, Shyam Gopalakrishnan, Graham Gower, Holly Heiniger, Kristofer M. Helgen, Josh Kapp, Pavel A. Kosintsev, Anna Linderholm, Andrew T. Ozga, Samantha Presslee, Alexander T. Salis, Nedda F. Saremi, Colin Shew, Katherine Skerry, Dmitry E. Taranenko, Mary Thompson, Mikhail V. Sablin, Yaroslav V. Kuzmin, Matthew J. Collins, Mikkel-Holger S. Sinding, M. Thomas P. Gilbert, Anne C. Stone, Beth Shapiro, Blaire Valkenburgh, Robert K. Wayne, Greger Larson, Alan Cooper and Laurent A. F. Frantz

Genetic mechanisms of critical illness in COVID-19 pp. 92-98

Erola Pairo-Castineira, Sara Clohisey, Lucija Klaric, Andrew D. Bretherick, Konrad Rawlik, Dorota Pasko, Susan Walker, Nick Parkinson, Max Head Fourman, Clark D. Russell, James Furniss, Anne Richmond, Elvina Gountouna, Nicola Wrobel, David Harrison, Bo Wang, Yang Wu, Alison Meynert, Fiona Griffiths, Wilna Oosthuyzen, Athanasios Kousathanas, Loukas Moutsianas, Zhijian Yang, Ranran Zhai, Chenqing Zheng, Graeme Grimes, Rupert Beale, Jonathan Millar, Barbara Shih, Sean Keating, Marie Zechner, Chris Haley, David J. Porteous, Caroline Hayward, Jian Yang, Julian Knight, Charlotte Summers, Manu Shankar-Hari, Paul Klenerman, Lance Turtle, Antonia Ho, Shona C. Moore, Charles Hinds, Peter Horby, Alistair Nichol, David Maslove, Lowell Ling, Danny McAuley, Hugh Montgomery, Timothy Walsh, Alexandre C. Pereira, Alessandra Renieri, Xia Shen, Chris P. Ponting, Angie Fawkes, Albert Tenesa, Mark Caulfield, Richard Scott, Kathy Rowan, Lee Murphy, Peter J. M. Openshaw, Malcolm G. Semple, Andrew Law, Veronique Vitart, James F. Wilson and J. Kenneth Baillie

Structural and developmental principles of neuropil assembly in C. elegans pp. 99-104

Mark W. Moyle, Kristopher M. Barnes, Manik Kuchroo, Alex Gonopolskiy, Leighton H. Duncan, Titas Sengupta, Lin Shao, Min Guo, Anthony Santella, Ryan Christensen, Abhishek Kumar, Yicong Wu, Kevin R. Moon, Guy Wolf, Smita Krishnaswamy, Zhirong Bao, Hari Shroff, William A. Mohler and Daniel A. Colón-Ramos

A multi-scale brain map derived from whole-brain volumetric reconstructions pp. 105-110

Christopher A. Brittin, Steven J. Cook, David H. Hall, Scott W. Emmons and Netta Cohen

Structure and function of a neocortical synapse pp. 111-116

Simone Holler, German Köstinger, Kevan A. C. Martin, Gregor F. P. Schuhknecht and Ken J. Stratford

Chaperone-mediated autophagy sustains haematopoietic stem-cell function pp. 117-123

Shuxian Dong, Qian Wang, Yun-Ruei Kao, Antonio Diaz, Inmaculada Tasset, Susmita Kaushik, Victor Thiruthuvanathan, Aliona Zintiridou, Edward Nieves, Monika Dzieciatkowska, Julie A. Reisz, Evripidis Gavathiotis, Angelo D’Alessandro, Britta Will and Ana Maria Cuervo

Global absence and targeting of protective immune states in severe COVID-19 pp. 124-130

Alexis J. Combes, Tristan Courau, Nicholas F. Kuhn, Kenneth H. Hu, Arja Ray, William S. Chen, Nayvin W. Chew, Simon J. Cleary, Divyashree Kushnoor, Gabriella C. Reeder, Alan Shen, Jessica Tsui, Kamir J. Hiam-Galvez, Priscila Muñoz-Sandoval, Wandi S. Zhu, David S. Lee, Yang Sun, Ran You, Mélia Magnen, Lauren Rodriguez, K. W. Im, Nina K. Serwas, Aleksandra Leligdowicz, Colin R. Zamecnik, Rita P. Loudermilk, Michael R. Wilson, Chun J. Ye, Gabriela K. Fragiadakis, Mark R. Looney, Vincent Chan, Alyssa Ward, Sidney Carrillo, Michael Matthay, David J. Erle, Prescott G. Woodruff, Charles Langelier, Kirsten Kangelaris, Carolyn M. Hendrickson, Carolyn Calfee, Arjun Arkal Rao and Matthew F. Krummel

NINJ1 mediates plasma membrane rupture during lytic cell death pp. 131-136

Nobuhiko Kayagaki, Opher S. Kornfeld, Bettina L. Lee, Irma B. Stowe, Karen O’Rourke, Qingling Li, Wendy Sandoval, Donghong Yan, Jing Kang, Min Xu, Juan Zhang, Wyne P. Lee, Brent S. McKenzie, Gözde Ulas, Jian Payandeh, Merone Roose-Girma, Zora Modrusan, Rohit Reja, Meredith Sagolla, Joshua D. Webster, Vicky Cho, T. Daniel Andrews, Lucy X. Morris, Lisa A. Miosge, Christopher C. Goodnow, Edward M. Bertram and Vishva M. Dixit

Chromothripsis drives the evolution of gene amplification in cancer pp. 137-141

Ofer Shoshani, Simon F. Brunner, Rona Yaeger, Peter Ly, Yael Nechemia-Arbely, Dong Hyun Kim, Rongxin Fang, Guillaume A. Castillon, Miao Yu, Julia S. Z. Li, Ying Sun, Mark H. Ellisman, Bing Ren, Peter J. Campbell and Don W. Cleveland

Wetting regulates autophagy of phase-separated compartments and the cytosol pp. 142-146

Jaime Agudo-Canalejo, Sebastian W. Schultz, Haruka Chino, Simona M. Migliano, Chieko Saito, Ikuko Koyama-Honda, Harald Stenmark, Andreas Brech, Alexander I. May, Noboru Mizushima and Roland L. Knorr

Systematic analysis of binding of transcription factors to noncoding variants pp. 147-151

Jian Yan, Yunjiang Qiu, André M. Ribeiro dos Santos, Yimeng Yin, Yang E. Li, Nick Vinckier, Naoki Nariai, Paola Benaglio, Anugraha Raman, Xiaoyu Li, Shicai Fan, Joshua Chiou, Fulin Chen, Kelly A. Frazer, Kyle J. Gaulton, Maike Sander, Jussi Taipale and Bing Ren

The kinetic landscape of an RNA-binding protein in cells pp. 152-156

Deepak Sharma, Leah L. Zagore, Matthew M. Brister, Xuan Ye, Carlos E. Crespo-Hernández, Donny D. Licatalosi and Eckhard Jankowsky

Structure and inhibition mechanism of the human citrate transporter NaCT pp. 157-161

David B. Sauer, Jinmei Song, Bing Wang, Jacob K. Hilton, Nathan K. Karpowich, Joseph A. Mindell, William J. Rice and Da-Neng Wang

We’ll meet again: scientists’ post-pandemic wish list pp. 163-164

Chris Woolston

Coronavirus diaries: Laughter is the best medicine pp. 165-165

John Tregoning

How to get started in quantum computing pp. 166-167

David Matthews

My race against time to capture the sounds of ancient rainforests pp. 170-170

James Mitchell Crow