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2016, volume 539, articles 7630

Ephrin Bs and canonical Reelin signalling pp. E4-E6

Theresa Pohlkamp, Lei Xiao, Rukhsana Sultana, Asim Bepari, Hans H. Bock, Mark Henkemeyer and Joachim Herz

Sentürk et al. reply pp. E6-E7

A. Sentürk, S. Pfennig, A. Weiss, K. Burk and A. Acker-Palmer

Contesting the massacre at Nataruk pp. E8-E10

Christopher M. Stojanowski, Andrew C. Seidel, Laura C. Fulginiti, Kent M. Johnson and Jane E. Buikstra

Mirazón Lahr et al. reply pp. E10-E11

M. Mirazón Lahr, F. Rivera, R. K. Power, A. Mounier, B. Copsey, F. Crivellaro, J. E. Edung, J. M. Maillo Fernandez, C. Kiarie, J. Lawrence, A. Leakey, E. Mbua, H. Miller, A. Muigai, D. M. Mukhongo, A. Van Baelen, R. Wood, J.-L. Schwenninger, R. Grün, H. Achyuthan, A. Wilshaw and R. A. Foley

Stand firm on hormone disruptors pp. 469-469

Leonardo Trasande

First Middle Eastern X-ray factory readies for action pp. 475-476

Elizabeth Gibney

Immigrant and minority scientists shaken by Trump win pp. 476-477

Heidi Ledford, Sara Reardon and Ramin Skibba

Rock core from dinosaur-killing impact reveals how enormous craters form pp. 478-478

Alexandra Witze

CRISPR gene-editing tested in a person for the first time pp. 479-479

David Cyranoski

Brazil’s scientists battle to escape 20-year funding freeze pp. 480-480

Claudio Angelo

The sparrow with four sexes pp. 482-484

Carrie Arnold

Fire up the atom forge pp. 485-487

Sergei V. Kalinin, Albina Borisevich and Stephen Jesse

Print flexible solar cells pp. 488-489

Yi-Bing Cheng, Alex Pascoe, Fuzhi Huang and Yong Peng

History: Women who read the stars pp. 491-492

Sue Nelson

Politics: Life at the divide pp. 492-493

Alison Abbott

Ecology: Winged insights pp. 493-494

H. Charles J. Godfray

Trump: China could take lead on climate pp. 495-495

David Victor

Trump: keep climate plans to boost jobs pp. 495-495

Jane C. S. Long

Trump: unlikely to deter clean energy pp. 495-495

Jessika Trancik

Trump: threats to space science? pp. 495-495

Monica Grady

Illness should not curtail PhD funding pp. 495-495

Edwin S. Dalmaijer, E. A. Claudia Pama and Stella Prins

Clamping down on copy errors pp. 498-499

Neil M. Kad and Bennett Van Houten

Polymers make charge flow easy pp. 499-500

Antonio Facchetti

Insect invasions and natural selection pp. 500-502

Amro Zayed

Flexible graphene strengthens friction pp. 502-503

Astrid S. de Wijn

A mitochondrial brake on vascular repair pp. 503-504

Charles E. de Bock and Rick F. Thorne

Improving the image of nanoparticles pp. 505-506

Christopher S. Wood and Molly M. Stevens

A war over water when bacteria invade leaves pp. 506-507

Gwyn A. Beattie

Emergent phenomena induced by spin–orbit coupling at surfaces and interfaces pp. 509-517

Anjan Soumyanarayanan, Nicolas Reyren, Albert Fert and Christos Panagopoulos

Developmental mechanisms of stripe patterns in rodents pp. 518-523

Ricardo Mallarino, Corneliu Henegar, Mercedes Mirasierra, Marie Manceau, Carsten Schradin, Mario Vallejo, Slobodan Beronja, Gregory S. Barsh and Hopi E. Hoekstra

Bacteria establish an aqueous living space in plants crucial for virulence pp. 524-529

Xiu-Fang Xin, Kinya Nomura, Kyaw Aung, André C. Velásquez, Jian Yao, Freddy Boutrot, Jeff H. Chang, Cyril Zipfel and Sheng Yang He

The mechanism of force transmission at bacterial focal adhesion complexes pp. 530-535

Laura M. Faure, Jean-Bernard Fiche, Leon Espinosa, Adrien Ducret, Vivek Anantharaman, Jennifer Luciano, Sébastien Lhospice, Salim T. Islam, Julie Tréguier, Mélanie Sotes, Erkin Kuru, Michael S. Van Nieuwenhze, Yves V. Brun, Olivier Théodoly, L. Aravind, Marcelo Nollmann and Tâm Mignot

Doped polymer semiconductors with ultrahigh and ultralow work functions for ohmic contacts pp. 536-540

Cindy G. Tang, Mervin C. Y. Ang, Kim-Kian Choo, Venu Keerthi, Jun-Kai Tan, Mazlan Nur Syafiqah, Thomas Kugler, Jeremy H. Burroughes, Rui-Qi Png, Lay-Lay Chua and Peter K. H. Ho

The evolving quality of frictional contact with graphene pp. 541-545

Suzhi Li, Qunyang Li, Robert W. Carpick, Peter Gumbsch, Xin Z. Liu, Xiangdong Ding, Jun Sun and Ju Li

Catalytic activation of carbon–carbon bonds in cyclopentanones pp. 546-550

Ying Xia, Gang Lu, Peng Liu and Guangbin Dong

Magnetic reversals from planetary dynamo waves pp. 551-554

Andrey Sheyko, Christopher C. Finlay and Andrew Jackson

A cannabinoid link between mitochondria and memory pp. 555-559

Etienne Hebert-Chatelain, Tifany Desprez, Román Serrat, Luigi Bellocchio, Edgar Soria-Gomez, Arnau Busquets-Garcia, Antonio Christian Pagano Zottola, Anna Delamarre, Astrid Cannich, Peggy Vincent, Marjorie Varilh, Laurie M. Robin, Geoffrey Terral, M. Dolores García-Fernández, Michelangelo Colavita, Wilfrid Mazier, Filippo Drago, Nagore Puente, Leire Reguero, Izaskun Elezgarai, Jean-William Dupuy, Daniela Cota, Maria-Luz Lopez-Rodriguez, Gabriel Barreda-Gómez, Federico Massa, Pedro Grandes, Giovanni Bénard and Giovanni Marsicano

Designer matrices for intestinal stem cell and organoid culture pp. 560-564

Nikolce Gjorevski, Norman Sachs, Andrea Manfrin, Sonja Giger, Maiia E. Bragina, Paloma Ordóñez-Morán, Hans Clevers and Matthias P. Lutolf

Different tissue phagocytes sample apoptotic cells to direct distinct homeostasis programs pp. 565-569

Ryan J. Cummings, Gaetan Barbet, Gerold Bongers, Boris M. Hartmann, Kyle Gettler, Luciana Muniz, Glaucia C. Furtado, Judy Cho, Sergio A. Lira and J. Magarian Blander

Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation pp. 570-574

Claudia Z. Han, Ignacio J. Juncadella, Jason M. Kinchen, Monica W. Buckley, Alexander L. Klibanov, Kelly Dryden, Suna Onengut-Gumuscu, Uta Erdbrügger, Stephen D. Turner, Yun M. Shim, Kenneth S. Tung and Kodi S. Ravichandran

Control of mitochondrial function and cell growth by the atypical cadherin Fat1 pp. 575-578

Longyue L. Cao, Dario F. Riascos-Bernal, Prameladevi Chinnasamy, Charlene M. Dunaway, Rong Hou, Mario A. Pujato, Brian P. O’Rourke, Veronika Miskolci, Liang Guo, Louis Hodgson, Andras Fiser and Nicholas E. S. Sibinga

Mechanism of super-assembly of respiratory complexes III and IV pp. 579-582

Sara Cogliati, Enrique Calvo, Marta Loureiro, Adela M. Guaras, Rocio Nieto-Arellano, Carolina Garcia-Poyatos, Iakes Ezkurdia, Nadia Mercader, Jesús Vázquez and José Antonio Enriquez

Cascading MutS and MutL sliding clamps control DNA diffusion to activate mismatch repair pp. 583-587

Jiaquan Liu, Jeungphill Hanne, Brooke M. Britton, Jared Bennett, Daehyung Kim, Jong-Bong Lee and Richard Fishel

Genetic and mechanistic diversity of piRNA 3′-end formation pp. 588-592

Rippei Hayashi, Jakob Schnabl, Dominik Handler, Fabio Mohn, Stefan L. Ameres and Julius Brennecke

An oxidative N-demethylase reveals PAS transition from ubiquitous sensor to enzyme pp. 593-597

Mary Ortmayer, Pierre Lafite, Binuraj R. K. Menon, Tewes Tralau, Karl Fisher, Lukas Denkhaus, Nigel S. Scrutton, Stephen E. J. Rigby, Andrew W. Munro, Sam Hay and David Leys

Correction: Corrigendum: Slowly fading super-luminous supernovae that are not pair-instability explosions pp. 598-598

M. Nicholl, S. J. Smartt, A. Jerkstrand, C. Inserra, M. McCrum, R. Kotak, M. Fraser, D. Wright, T.-W. Chen, K. Smith, D. R. Young, S. A. Sim, S. Valenti, D. A. Howell, F. Bresolin, R. P. Kudritzki, J. L. Tonry, M. E. Huber, A. Rest, A. Pastorello, L. Tomasella, E. Cappellaro, S. Benetti, S. Mattila, E. Kankare, T. Kangas, G. Leloudas, J. Sollerman, F. Taddia, E. Berger, R. Chornock, G. Narayan, C. W. Stubbs, R. J. Foley, R. Lunnan, A. Soderberg, N. Sanders, D. Milisavljevic, R. Margutti, R. P. Kirshner, N. Elias-Rosa, A. Morales-Garoffolo, S. Taubenberger, M. T. Botticella, S. Gezari, Y. Urata, S. Rodney, A. G. Riess, D. Scolnic, W. M. Wood-Vasey, W. S. Burgett, K. Chambers, H. A. Flewelling, E. A. Magnier, N. Kaiser, N. Metcalfe, J. Morgan, P. A. Price, W. Sweeney and C. Waters

Activism: A call to serve pp. 599-600

Chris Woolston

Hungry ghosts pp. 602-602

Cassandra Khaw

2016, volume 539, articles 7629

Nature Index 2016 Collaborations pp. S1-S1

Nicky Phillips

How they stack up pp. S4-S5

Larissa Kogleck

Science superpowers find common ground pp. S6-S9

Sujata Gupta

Old bonds and elemental connections pp. S14-S19

Tim Hornyak and Barbara Casassus

Applying local knowledge pp. S20-S24

Neil Savage

Closing the channel of opportunity pp. S26-S29

Mark Peplow

Science and innovation policies for Donald Trump pp. 331-331

Daniel Sarewitz

The ultimate experiment: How Trump will handle science pp. 337-339

Sara Reardon, Jeff Tollefson, Alexandra Witze and Lauren Morello

Pollsters struggle to explain failures of US presidential forecasts pp. 339-339

Ramin Skibba

Disgraced stem-cell entrepreneur under fresh investigation pp. 340-340

Alison Abbott

I can haz more science emoji? Host of nerd icons proposed pp. 341-341

Katherine Bourzac

Rwanda feels the pinch as donors slash health aid pp. 342-342

Erika Check Hayden

Open peer review finds more takers pp. 343-343

Ewen Callaway

How much longer can Antarctica’s hostile ocean delay global warming? pp. 346-348

Jeff Tollefson

Carbon is not the enemy pp. 349-351

William McDonough

Public health: Gore and glory pp. 354-355

David Dobbs

Books in brief pp. 355-355

Barbara Kiser

History: Untangling Alice pp. 356-356

Gillian Beer

UK research reform: protest now pp. 357-357

Stephen Curry, Jenny Rohn and Andrew Steele

UK research reform: poor timing pp. 357-357

Martin Rees

UK research reform: get the facts straight pp. 357-357

Leszek K. Borysiewicz

Genetics boosts US–Cuban links pp. 357-357

Rosario Isasi, Stephan L. Zuchner and Roberto Cañete Villafranca

Precision oncology is not an illusion pp. 357-357

Edward Abrahams and Stephen L. Eck

Joseph L. Birman (1927–2016) pp. 358-358

Eugene M. Chudnovsky

Clear directions for random lasers pp. 360-361

Diederik S. Wiersma

Mature proteins braced by a chaperone pp. 361-362

Qinglian Liu and Elizabeth A. Craig

Ions surprise in Earth's deep fluids pp. 362-364

David Dolejš

Sleepy and dreamless mutant mice pp. 364-365

Derk-Jan Dijk and Raphaëlle Winsky-Sommerer

Semiconductors that stretch and heal pp. 365-367

Siegfried Bauer and Martin Kaltenbrunner

Deep-sea secrets of butane metabolism pp. 367-368

Stephen W. Ragsdale

The effects of Δ9-tetrahydrocannabinol on the dopamine system pp. 369-377

Michael A. P. Bloomfield, Abhishekh H. Ashok, Nora D. Volkow and Oliver D. Howes

Forward-genetics analysis of sleep in randomly mutagenized mice pp. 378-383

Hiromasa Funato, Chika Miyoshi, Tomoyuki Fujiyama, Takeshi Kanda, Makito Sato, Zhiqiang Wang, Jing Ma, Shin Nakane, Jun Tomita, Aya Ikkyu, Miyo Kakizaki, Noriko Hotta-Hirashima, Satomi Kanno, Haruna Komiya, Fuyuki Asano, Takato Honda, Staci J. Kim, Kanako Harano, Hiroki Muramoto, Toshiya Yonezawa, Seiya Mizuno, Shinichi Miyazaki, Linzi Connor, Vivek Kumar, Ikuo Miura, Tomohiro Suzuki, Atsushi Watanabe, Manabu Abe, Fumihiro Sugiyama, Satoru Takahashi, Kenji Sakimura, Yu Hayashi, Qinghua Liu, Kazuhiko Kume, Shigeharu Wakana, Joseph S. Takahashi and Masashi Yanagisawa

CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells pp. 384-389

Daniel P. Dever, Rasmus O. Bak, Andreas Reinisch, Joab Camarena, Gabriel Washington, Carmencita E. Nicolas, Mara Pavel-Dinu, Nivi Saxena, Alec B. Wilkens, Sruthi Mantri, Nobuko Uchida, Ayal Hendel, Anupama Narla, Ravindra Majeti, Kenneth I. Weinberg and Matthew H. Porteus

LKB1 loss links serine metabolism to DNA methylation and tumorigenesis pp. 390-395

Filippos Kottakis, Brandon N. Nicolay, Ahlima Roumane, Rahul Karnik, Hongcang Gu, Julia M. Nagle, Myriam Boukhali, Michele C. Hayward, Yvonne Y. Li, Ting Chen, Marc Liesa, Peter S. Hammerman, Kwok Kin Wong, D. Neil Hayes, Orian S. Shirihai, Nicholas J. Dyson, Wilhelm Haas, Alexander Meissner and Nabeel Bardeesy

Thermophilic archaea activate butane via alkyl-coenzyme M formation pp. 396-401

Rafael Laso-Pérez, Gunter Wegener, Katrin Knittel, Friedrich Widdel, Katie J. Harding, Viola Krukenberg, Dimitri V. Meier, Michael Richter, Halina E. Tegetmeyer, Dietmar Riedel, Hans-Hermann Richnow, Lorenz Adrian, Thorsten Reemtsma, Oliver J. Lechtenfeld and Florin Musat

Tidal evolution of the Moon from a high-obliquity, high-angular-momentum Earth pp. 402-406

Matija Ćuk, Douglas P. Hamilton, Simon J. Lock and Sarah T. Stewart

Nanoscale thermal imaging of dissipation in quantum systems pp. 407-410

D. Halbertal, J. Cuppens, M. Ben Shalom, L. Embon, N. Shadmi, Y. Anahory, H. R. Naren, J. Sarkar, A. Uri, Y. Ronen, Y. Myasoedov, L. S. Levitov, E. Joselevich, A. K. Geim and E. Zeldov

Intrinsically stretchable and healable semiconducting polymer for organic transistors pp. 411-415

Jin Young Oh, Simon Rondeau-Gagné, Yu-Cheng Chiu, Alex Chortos, Franziska Lissel, Ging-Ji Nathan Wang, Bob C. Schroeder, Tadanori Kurosawa, Jeffrey Lopez, Toru Katsumata, Jie Xu, Chenxin Zhu, Xiaodan Gu, Won-Gyu Bae, Yeongin Kim, Lihua Jin, Jong Won Chung, Jeffrey B.-H. Tok and Zhenan Bao

Amazon boundary layer aerosol concentration sustained by vertical transport during rainfall pp. 416-419

Jian Wang, Radovan Krejci, Scott Giangrande, Chongai Kuang, Henrique M. J. Barbosa, Joel Brito, Samara Carbone, Xuguang Chi, Jennifer Comstock, Florian Ditas, Jost Lavric, Hanna E. Manninen, Fan Mei, Daniel Moran-Zuloaga, Christopher Pöhlker, Mira L. Pöhlker, Jorge Saturno, Beat Schmid, Rodrigo A. F. Souza, Stephen R. Springston, Jason M. Tomlinson, Tami Toto, David Walter, Daniela Wimmer, James N. Smith, Markku Kulmala, Luiz A. T. Machado, Paulo Artaxo, Meinrat O. Andreae, Tuukka Petäjä and Scot T. Martin

Implications for metal and volatile cycles from the pH of subduction zone fluids pp. 420-424

Matthieu E. Galvez, James A. D. Connolly and Craig E. Manning

Variability in plant nutrients reduces insect herbivore performance pp. 425-427

William C. Wetzel, Heather M. Kharouba, Moria Robinson, Marcel Holyoak and Richard Karban

Neuromodulators signal through astrocytes to alter neural circuit activity and behaviour pp. 428-432

Zhiguo Ma, Tobias Stork, Dwight E. Bergles and Marc R. Freeman

Transcription of the non-coding RNA upperhand controls Hand2 expression and heart development pp. 433-436

Kelly M. Anderson, Douglas M. Anderson, John R. McAnally, John M. Shelton, Rhonda Bassel-Duby and Eric N. Olson

PI3Kγ is a molecular switch that controls immune suppression pp. 437-442

Megan M. Kaneda, Karen S. Messer, Natacha Ralainirina, Hongying Li, Christopher J. Leem, Sara Gorjestani, Gyunghwi Woo, Abraham V. Nguyen, Camila C. Figueiredo, Philippe Foubert, Michael C. Schmid, Melissa Pink, David G. Winkler, Matthew Rausch, Vito J. Palombella, Jeffery Kutok, Karen McGovern, Kelly A. Frazer, Xuefeng Wu, Michael Karin, Roman Sasik, Ezra E. W. Cohen and Judith A. Varner

Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells pp. 443-447

Olivier De Henau, Matthew Rausch, David Winkler, Luis Felipe Campesato, Cailian Liu, Daniel Hirschhorn Cymerman, Sadna Budhu, Arnab Ghosh, Melissa Pink, Jeremy Tchaicha, Mark Douglas, Thomas Tibbitts, Sujata Sharma, Jennifer Proctor, Nicole Kosmider, Kerry White, Howard Stern, John Soglia, Julian Adams, Vito J. Palombella, Karen McGovern, Jeffery L. Kutok, Jedd D. Wolchok and Taha Merghoub

Alternative modes of client binding enable functional plasticity of Hsp70 pp. 448-451

Alireza Mashaghi, Sergey Bezrukavnikov, David P. Minde, Anne S. Wentink, Roman Kityk, Beate Zachmann-Brand, Matthias P. Mayer, Günter Kramer, Bernd Bukau and Sander J. Tans

Local regulation of gene expression by lncRNA promoters, transcription and splicing pp. 452-455

Jesse M. Engreitz, Jenna E. Haines, Elizabeth M. Perez, Glen Munson, Jenny Chen, Michael Kane, Patrick E. McDonel, Mitchell Guttman and Eric S. Lander

Correction: Corrigendum: An early geodynamo driven by exsolution of mantle components from Earth’s core pp. 456-456

James Badro, Julien Siebert and Francis Nimmo

Erratum: Replication fork stability confers chemoresistance in BRCA-deficient cells pp. 456-456

Arnab Ray Chaudhuri, Elsa Callen, Xia Ding, Ewa Gogola, Alexandra A. Duarte, Ji-Eun Lee, Nancy Wong, Vanessa Lafarga, Jennifer A. Calvo, Nicholas J. Panzarino, Sam John, Amanda Day, Anna Vidal Crespo, Binghui Shen, Linda M. Starnes, Julian R. de Ruiter, Jeremy A. Daniel, Panagiotis A. Konstantinopoulos, David Cortez, Sharon B. Cantor, Oscar Fernandez-Capetillo, Kai Ge, Jos Jonkers, Sven Rottenberg, Shyam K. Sharan and André Nussenzweig

Correction: Corrigendum: An essential receptor for adeno-associated virus infection pp. 456-456

S. Pillay, N. L. Meyer, A. S. Puschnik, O. Davulcu, J. Diep, Y. Ishikawa, L. T. Jae, J. E. Wosen, C. M. Nagamine, M. S. Chapman and J. E. Carette

Education: The gamble of a PhD hiatus pp. 457-459

Eryn Brown

Trade talk: Industrial shift pp. 459-459

Monya Baker

Box 27 pp. 462-462

Kevin Lauderdale

2016, volume 539, articles 7628

The insect crisis we can’t ignore pp. 141-141

Axel Hochkirch

Political upheaval threatens Brazil’s environmental protections pp. 147-148

Jeff Tollefson

Brexit chancellor’s annual address is a science nail-biter pp. 148-149

Elizabeth Gibney

The quiet rise of the NIH’s hot new metric pp. 150-150

Gautam Naik

Big brain projects urged to aid public health pp. 151-151

Sara Reardon

Quest to map Africa’s soil microbiome begins pp. 152-152

Sarah Wild

Tracker flags up failures to report clinical trials pp. 153-153

Heidi Ledford

How to defeat dementia pp. 156-158

Elie Dolgin

A better way to crack the brain pp. 159-161

Zachary F. Mainen, Michael Häusser and Alexandre Pouget

Forecast ocean variability pp. 162-163

Daniela Schmidt and Philip W. Boyd

Neuroscience: Tide of forgetting pp. 166-167

Michael Heneka

Books in brief pp. 167-167

Barbara Kiser

Revise rules on conflicts of interest pp. 168-168

Indrė Žliobaitė and Mikael Fortelius

Preserve specimens for reproducibility pp. 168-168

Frank T. Krell

Open up research evaluation in China pp. 168-168

Lihua Yang

Australia too casual with protection law pp. 168-168

Christian Vincenot and Sophie Petit

Renewables from the bottom up pp. 168-168

Jari Lyytimäki

Single-molecule instant replay pp. 170-171

Nicholas Camillone

Genomic remodelling in the primate brain pp. 171-172

Justine Kupferman and Franck Polleux

Cliffs make a hasty retreat pp. 173-173

Ryan Wilkinson

Bad neighbours cause bad blood pp. 173-175

Gordon Chan and Benjamin G. Neel

Eighty years of stress pp. 175-176

George Fink

A strange kind of liquid pp. 176-177

Bruno Laburthe-Tolra

Neural interfaces take another step forward pp. 177-178

Andrew Jackson

Neurodegenerative diseases pp. 179-179

Marie-Thérèse Heemels

Ageing, neurodegeneration and brain rejuvenation pp. 180-186

Tony Wyss-Coray

The road to restoring neural circuits for the treatment of Alzheimer's disease pp. 187-196

Rebecca G. Canter, Jay Penney and Li-Huei Tsai

Decoding ALS: from genes to mechanism pp. 197-206

J. Paul Taylor, Robert H. Brown and Don W. Cleveland

Defects in trafficking bridge Parkinson's disease pathology and genetics pp. 207-216

Asa Abeliovich and Aaron D. Gitler

Mammalian prions and their wider relevance in neurodegenerative diseases pp. 217-226

John Collinge

The activities of amyloids from a structural perspective pp. 227-235

Roland Riek and David S. Eisenberg

The stem osteichthyan Andreolepis and the origin of tooth replacement pp. 237-241

Donglei Chen, Henning Blom, Sophie Sanchez, Paul Tafforeau and Per E. Ahlberg

Evolution of Osteocrin as an activity-regulated factor in the primate brain pp. 242-247

Bulent Ataman, Gabriella L. Boulting, David A. Harmin, Marty G. Yang, Mollie Baker-Salisbury, Ee-Lynn Yap, Athar N. Malik, Kevin Mei, Alex A. Rubin, Ivo Spiegel, Ershela Durresi, Nikhil Sharma, Linda S. Hu, Mihovil Pletikos, Eric C. Griffith, Jennifer N. Partlow, Christine R. Stevens, Mazhar Adli, Maria Chahrour, Nenad Sestan, Christopher A. Walsh, Vladimir K. Berezovskii, Margaret S. Livingstone and Michael E. Greenberg

Transplanted embryonic neurons integrate into adult neocortical circuits pp. 248-253

Susanne Falkner, Sofia Grade, Leda Dimou, Karl-Klaus Conzelmann, Tobias Bonhoeffer, Magdalena Götz and Mark Hübener

Balancing selection shapes density-dependent foraging behaviour pp. 254-258

Joshua S. Greene, Maximillian Brown, May Dobosiewicz, Itzel G. Ishida, Evan Z. Macosko, Xinxing Zhang, Rebecca A. Butcher, Devin J. Cline, Patrick T. McGrath and Cornelia I. Bargmann

Self-bound droplets of a dilute magnetic quantum liquid pp. 259-262

Matthias Schmitt, Matthias Wenzel, Fabian Böttcher, Igor Ferrier-Barbut and Tilman Pfau

Tracking the ultrafast motion of a single molecule by femtosecond orbital imaging pp. 263-267

Tyler L. Cocker, Dominik Peller, Ping Yu, Jascha Repp and Rupert Huber

Catalytic alkylation of remote C–H bonds enabled by proton-coupled electron transfer pp. 268-271

Gilbert J. Choi, Qilei Zhu, David C. Miller, Carol J. Gu and Robert R. Knowles

Amide-directed photoredox-catalysed C–C bond formation at unactivated sp3 C–H bonds pp. 272-275

John C. K. Chu and Tomislav Rovis

Fluvial sediment supply to a mega-delta reduced by shifting tropical-cyclone activity pp. 276-279

Stephen E. Darby, Christopher R. Hackney, Julian Leyland, Matti Kummu, Hannu Lauri, Daniel R. Parsons, James L. Best, Andrew P. Nicholas and Rolf Aalto

Cultural innovation and megafauna interaction in the early settlement of arid Australia pp. 280-283

Giles Hamm, Peter Mitchell, Lee J. Arnold, Gavin J. Prideaux, Daniele Questiaux, Nigel A. Spooner, Vladimir A. Levchenko, Elizabeth C. Foley, Trevor H. Worthy, Birgitta Stephenson, Vincent Coulthard, Clifford Coulthard, Sophia Wilton and Duncan Johnston

A brain–spine interface alleviating gait deficits after spinal cord injury in primates pp. 284-288

Marco Capogrosso, Tomislav Milekovic, David Borton, Fabien Wagner, Eduardo Martin Moraud, Jean-Baptiste Mignardot, Nicolas Buse, Jerome Gandar, Quentin Barraud, David Xing, Elodie Rey, Simone Duis, Yang Jianzhong, Wai Kin D. Ko, Qin Li, Peter Detemple, Tim Denison, Silvestro Micera, Erwan Bezard, Jocelyne Bloch and Grégoire Courtine

A basal ganglia circuit for evaluating action outcomes pp. 289-293

Marcus Stephenson-Jones, Kai Yu, Sandra Ahrens, Jason M. Tucciarone, Aile N. van Huijstee, Luis A. Mejia, Mario A. Penzo, Lung-Hao Tai, Linda Wilbrecht and Bo Li

Fatty acid synthesis configures the plasma membrane for inflammation in diabetes pp. 294-298

Xiaochao Wei, Haowei Song, Li Yin, Michael G. Rizzo, Rohini Sidhu, Douglas F. Covey, Daniel S. Ory and Clay F. Semenkovich

Reconstitution in vitro of the entire cycle of the mouse female germ line pp. 299-303

Orie Hikabe, Nobuhiko Hamazaki, Go Nagamatsu, Yayoi Obata, Yuji Hirao, Norio Hamada, So Shimamoto, Takuya Imamura, Kinichi Nakashima, Mitinori Saitou and Katsuhiko Hayashi

Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment pp. 304-308

Lei Dong, Wen-Mei Yu, Hong Zheng, Mignon L. Loh, Silvia T. Bunting, Melinda Pauly, Gang Huang, Muxiang Zhou, Hal E. Broxmeyer, David T. Scadden and Cheng-Kui Qu

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma pp. 309-313

Itay Tirosh, Andrew S. Venteicher, Christine Hebert, Leah E. Escalante, Anoop P. Patel, Keren Yizhak, Jonathan M. Fisher, Christopher Rodman, Christopher Mount, Mariella G. Filbin, Cyril Neftel, Niyati Desai, Jackson Nyman, Benjamin Izar, Christina C. Luo, Joshua M. Francis, Aanand A. Patel, Maristela L. Onozato, Nicolo Riggi, Kenneth J. Livak, Dave Gennert, Rahul Satija, Brian V. Nahed, William T. Curry, Robert L. Martuza, Ravindra Mylvaganam, A. John Iafrate, Matthew P. Frosch, Todd R. Golub, Miguel N. Rivera, Gad Getz, Orit Rozenblatt-Rosen, Daniel P. Cahill, Michelle Monje, Bradley E. Bernstein, David N. Louis, Aviv Regev and Mario L. Suvà

Erratum: Structural basis of potent Zika–dengue virus antibody cross-neutralization pp. 314-314

Giovanna Barba-Spaeth, Wanwisa Dejnirattisai, Alexander Rouvinski, Marie-Christine Vaney, Iris Medits, Arvind Sharma, Etienne Simon-Lorière, Anavaj Sakuntabhai, Cao-Lormeau Van-Mai, Ahmed Haouz, Patrick England, Karin Stiasny, Juthathip Mongkolsapaya, Franz X. Heinz, Gavin R. Screaton and Félix A. Rey

Correction: Corrigendum: Human commensals producing a novel antibiotic impair pathogen colonization pp. 314-314

Alexander Zipperer, Martin C. Konnerth, Claudia Laux, Anne Berscheid, Daniela Janek, Christopher Weidenmaier, Marc Burian, Nadine A. Schilling, Christoph Slavetinsky, Matthias Marschal, Matthias Willmann, Hubert Kalbacher, Birgit Schittek, Heike Brötz-Oesterhelt, Stephanie Grond, Andreas Peschel and Bernhard Krismer

Correction: Corrigendum: Age-dependent modulation of vascular niches for haematopoietic stem cells pp. 314-314

Anjali P. Kusumbe, Saravana K. Ramasamy, Tomer Itkin, Maarja Andaloussi Mäe, Urs H. Langen, Christer Betsholtz, Tsvee Lapidot and Ralf H. Adams

The real-time technicolour living brain pp. 315-318

Amber Dance

Mental health: Caught in a trap pp. 319-321

Emily Sohn

Melissa pp. 324-324

Troy Stieglitz

2016, volume 539, articles 7627

The intrinsic thermal conductivity of SnSe pp. E1-E2

Pai-Chun Wei, S. Bhattacharya, J. He, S. Neeleshwar, R. Podila, Y. Y. Chen and A. M. Rao

Zhao et al. reply pp. E2-E3

Li-Dong Zhao, Shih-Han Lo, Yongsheng Zhang, Hui Sun, Gangjian Tan, Ctirad Uher, C. Wolverton, Vinayak P. Dravid and Mercouri G. Kanatzidis

Geneticists should offer data to participants pp. 7-7

Sarah Nelson

World’s largest marine reserve hailed as diplomatic breakthrough pp. 13-14

Quirin Schiermeier

Young scientists ditch postdocs for biotech start-ups pp. 14-15

Erika Check Hayden

Cosmic rays may threaten space-weather satellite pp. 15-16

Alexandra Witze

Plant-genome hackers seek better ways to produce customized crops pp. 16-17

Heidi Ledford

Rio fights Zika with biggest release yet of bacteria-infected mosquitoes pp. 17-18

Ewen Callaway

US mental-health chief: psychiatry must get serious about mathematics pp. 18-19

Alison Abbott

Can wind and solar fuel Africa's future? pp. 20-22

Erica Gies

Good data are not enough pp. 23-25

Avi Loeb

Bridge the planetary divide pp. 25-27

Ariel D. Anbar, Christy B. Till and Mark A. Hannah

Cryptography: Calligraphic conundrum pp. 28-29

Andrew Robinson

Zoology: Animal crackers pp. 29-30

Henry Nicholls

Norway wolf cull will hit genetic diversity pp. 31-31

Elina Immonen and Arild Husby

Inequality: need for data on all nations pp. 31-31

Mathieu Denis and Melissa Leach

Inequality: span the global divide pp. 31-31

Richard J. Smithers, Malgorzata Blicharska and José María Gutiérrez

Protect aquaculture from ship pathogens pp. 31-31

Guillaume Drillet

Small data call for big ideas pp. 31-31

Iadine Chadès and Sam Nicol

Stones that could cause ripples pp. 34-35

Hélène Roche

Telomere-lengthening mechanism revealed pp. 35-36

Caitlin M. Roake and Steven E. Artandi

Turbulence in a quantum gas pp. 36-37

Brian P. Anderson

Phosphate on, rubbish out pp. 38-39

Arti Tripathi and Susan Gottesman

Sound and meaning in the world's languages pp. 39-40

W. Tecumseh Fitch

Axions exposed pp. 40-41

Maria Paola Lombardo

De novo phasing with X-ray laser reveals mosquito larvicide BinAB structure pp. 43-47

Jacques-Philippe Colletier, Michael R. Sawaya, Mari Gingery, Jose A. Rodriguez, Duilio Cascio, Aaron S. Brewster, Tara Michels-Clark, Robert H. Hice, Nicolas Coquelle, Sébastien Boutet, Garth J. Williams, Marc Messerschmidt, Daniel P. DePonte, Raymond G. Sierra, Hartawan Laksmono, Jason E. Koglin, Mark S. Hunter, Hyun-Woo Park, Monarin Uervirojnangkoorn, Dennis K. Bideshi, Axel T. Brunger, Brian A. Federici, Nicholas K. Sauter and David S. Eisenberg

Arginine phosphorylation marks proteins for degradation by a Clp protease pp. 48-53

Débora Broch Trentini, Marcin Józef Suskiewicz, Alexander Heuck, Robert Kurzbauer, Luiza Deszcz, Karl Mechtler and Tim Clausen

Break-induced telomere synthesis underlies alternative telomere maintenance pp. 54-58

Robert L. Dilley, Priyanka Verma, Nam Woo Cho, Harrison D. Winters, Anne R. Wondisford and Roger A. Greenberg

Defining synonymous codon compression schemes by genome recoding pp. 59-64

Kaihang Wang, Julius Fredens, Simon F. Brunner, Samuel H. Kim, Tiongsun Chia and Jason W. Chin

The formation of Charon’s red poles from seasonally cold-trapped volatiles pp. 65-68

W. M. Grundy, D. P. Cruikshank, G. R. Gladstone, C. J. A. Howett, T. R. Lauer, J. R. Spencer, M. E. Summers, M. W. Buie, A. M. Earle, K. Ennico, J. Wm. Parker, S. B. Porter, K. N. Singer, S. A. Stern, A. J. Verbiscer, R. A. Beyer, R. P. Binzel, B. J. Buratti, J. C. Cook, C. M. Dalle Ore, C. B. Olkin, A. H. Parker, S. Protopapa, E. Quirico, K. D. Retherford, S. J. Robbins, B. Schmitt, J. A. Stansberry, O. M. Umurhan, H. A. Weaver, L. A. Young, A. M. Zangari, V. J. Bray, A. F. Cheng, W. B. McKinnon, R. L. McNutt, J. M. Moore, F. Nimmo, D. C. Reuter and P. M. Schenk

Calculation of the axion mass based on high-temperature lattice quantum chromodynamics pp. 69-71

S. Borsanyi, Z. Fodor, J. Guenther, K.-H. Kampert, S. D. Katz, T. Kawanai, T. G. Kovacs, S. W. Mages, A. Pasztor, F. Pittler, J. Redondo, A. Ringwald and K. K. Szabo

Emergence of a turbulent cascade in a quantum gas pp. 72-75

Nir Navon, Alexander L. Gaunt, Robert P. Smith and Zoran Hadzibabic

Metal–organic frameworks as selectivity regulators for hydrogenation reactions pp. 76-80

Meiting Zhao, Kuo Yuan, Yun Wang, Guodong Li, Jun Guo, Lin Gu, Wenping Hu, Huijun Zhao and Zhiyong Tang

Mantle dynamics inferred from the crystallographic preferred orientation of bridgmanite pp. 81-84

Noriyoshi Tsujino, Yu Nishihara, Daisuke Yamazaki, Yusuke Seto, Yuji Higo and Eiichi Takahashi

Wild monkeys flake stone tools pp. 85-88

Tomos Proffitt, Lydia V. Luncz, Tiago Falótico, Eduardo B. Ottoni, Ignacio de la Torre and Michael Haslam

Evolution of Hoxa11 regulation in vertebrates is linked to the pentadactyl state pp. 89-92

Yacine Kherdjemil, Robert L. Lalonde, Rushikesh Sheth, Annie Dumouchel, Gemma de Martino, Kyriel M. Pineault, Deneen M. Wellik, H. Scott Stadler, Marie-Andrée Akimenko and Marie Kmita

Olfactory receptor pseudo-pseudogenes pp. 93-97

Lucia L. Prieto-Godino, Raphael Rytz, Benoîte Bargeton, Liliane Abuin, J. Roman Arguello, Matteo Dal Peraro and Richard Benton

1970s and ‘Patient 0’ HIV-1 genomes illuminate early HIV/AIDS history in North America pp. 98-101

Michael Worobey, Thomas D. Watts, Richard A. McKay, Marc A. Suchard, Timothy Granade, Dirk E. Teuwen, Beryl A. Koblin, Walid Heneine, Philippe Lemey and Harold W. Jaffe

Single-cell RNA-seq identifies a PD-1hi ILC progenitor and defines its development pathway pp. 102-106

Yong Yu, Jason C. H. Tsang, Cui Wang, Simon Clare, Juexuan Wang, Xi Chen, Cordelia Brandt, Leanne Kane, Lia S. Campos, Liming Lu, Gabrielle T. Belz, Andrew N. J. McKenzie, Sarah A. Teichmann, Gordon Dougan and Pentao Liu

On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models pp. 107-111

Hyejin Cho, Xinlin Du, James P. Rizzi, Ella Liberzon, Abhishek A. Chakraborty, Wenhua Gao, Ingrid Carvo, Sabina Signoretti, Richard K. Bruick, John A. Josey, Eli M. Wallace and William G. Kaelin

Targeting renal cell carcinoma with a HIF-2 antagonist pp. 112-117

Wenfang Chen, Haley Hill, Alana Christie, Min Soo Kim, Eboni Holloman, Andrea Pavia-Jimenez, Farrah Homayoun, Yuanqing Ma, Nirav Patel, Paul Yell, Guiyang Hao, Qurratulain Yousuf, Allison Joyce, Ivan Pedrosa, Heather Geiger, He Zhang, Jenny Chang, Kevin H. Gardner, Richard K. Bruick, Catherine Reeves, Tae Hyun Hwang, Kevin Courtney, Eugene Frenkel, Xiankai Sun, Naseem Zojwalla, Tai Wong, James P. Rizzi, Eli M. Wallace, John A. Josey, Yang Xie, Xian-Jin Xie, Payal Kapur, Renée M. McKay and James Brugarolas

Atomic model for the membrane-embedded VO motor of a eukaryotic V-ATPase pp. 118-122

Mohammad T. Mazhab-Jafari, Alexis Rohou, Carla Schmidt, Stephanie A. Bueler, Samir Benlekbir, Carol V. Robinson and John L. Rubinstein

Correction: Corrigendum: Lytic to temperate switching of viral communities pp. 123-123

B. Knowles, C. B. Silveira, B. A. Bailey, K. Barott, V. A. Cantu, A. G. Cobián-Güemes, F. H. Coutinho, E. A. Dinsdale, B. Felts, K. A. Furby, E. E. George, K. T. Green, G. B. Gregoracci, A. F. Haas, J. M. Haggerty, E. R. Hester, N. Hisakawa, L. W. Kelly, Y. W. Lim, M. Little, A. Luque, T. McDole-Somera, K. McNair, L. S. de Oliveira, S. D. Quistad, N. L. Robinett, E. Sala, P. Salamon, S. E. Sanchez, S. Sandin, G. G. Z. Silva, J. Smith, C. Sullivan, C. Thompson, M. J. A. Vermeij, M. Youle, C. Young, B. Zgliczynski, R. Brainard, R. A. Edwards, J. Nulton, F. Thompson and F. Rohwer

Erratum: Formation of new stellar populations from gas accreted by massive young star clusters pp. 123-123

Chengyuan Li, Richard de Grijs, Licai Deng, Aaron M. Geller, Yu Xin, Yi Hu and Claude-André Faucher-Giguère

Correction: Corrigendum: Transfer of mitochondria from astrocytes to neurons after stroke pp. 123-123

Kazuhide Hayakawa, Elga Esposito, Xiaohua Wang, Yasukazu Terasaki, Yi Liu, Changhong Xing, Xunming Ji and Eng H. Lo

Correction: Corrigendum: Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells pp. 124-124

Jennifer Martinez, Larissa D. Cunha, Sunmin Park, Mao Yang, Qun Lu, Robert Orchard, Quan-Zhen Li, Mei Yan, Laura Janke, Cliff Guy, Andreas Linkermann, Herbert W. Virgin and Douglas R. Green

Mining the secrets of college syllabuses pp. 125-126

Anna Nowogrodzki

Postgraduate studies: Find the best fit pp. 127-129

Kendall Powell

Blood will tell pp. 132-132

Tom Easton and Jack McDevitt