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2012, volume 481, articles 7382

Cultural history holds back Chinese research pp. 411-411

Peng Gong

Caution urged for mutant flu work pp. 417-418

Declan Butler

UK sets sights on gene therapy in eggs pp. 419-419

Ewen Callaway

Research in Asia heats up pp. 420-420

Eugenie Samuel Reich

Candidates play to the right on science pp. 421-423

Susan Young

French institute prepares for gene-therapy push pp. 423-424

Alison Abbott

Underwater archaeology: Hunt for the ancient mariner pp. 426-428

Jo Marchant

Going paperless: The digital lab pp. 430-431

Jim Giles

Oil's tipping point has passed pp. 433-435

James Murray and David King

Provocative questions in cancer research pp. 436-437

Harold Varmus and Ed Harlow

Nuclear physics: Arms and the man pp. 438-439

Martin Rees

Cosmology: Plucked from the vacuum pp. 440-440

Caleb Scharf

Film: Science gets real at Sundance pp. 441-441

Jascha Hoffman

Pause on avian flu transmission studies pp. 443-443

Ron A. M. Fouchier, Adolfo García-Sastre and Yoshihiro Kawaoka

Train local experts to help conserve forests pp. 443-443

Charles M. Peters, Miguel Alexiades and Sarah A. Laird

Biobank donors should have a say pp. 443-443

Brenda Spencer, Daria Koutaissoff and Hans-Anton Lehr

James Crow (1916–2012) pp. 444-444

Alexey Kondrashov

Spikes timed through inhibition pp. 446-447

Javier F. Medina and Kamran Khodakhah

A new class of planet pp. 448-449

John Southworth

Hunter-gatherer cooperation pp. 449-450

Joseph Henrich

Shape matters pp. 450-452

Sharon C. Glotzer

Even harder X-rays pp. 452-453

Jon Marangos

The right neighbour pp. 453-454

Ilya A. Shestopalov and Leonard I. Zon

A deeper peek into living organisms pp. 454-454

Francesca Cesari and Deepa Nath

Chemical beauty contest pp. 455-456

Paul Leeson

Endothelial and perivascular cells maintain haematopoietic stem cells pp. 457-462

Lei Ding, Thomas L. Saunders, Grigori Enikolopov and Sean J. Morrison

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis pp. 463-468

Pontus Boström, Jun Wu, Mark P. Jedrychowski, Anisha Korde, Li Ye, James C. Lo, Kyle A. Rasbach, Elisabeth Almer Boström, Jang Hyun Choi, Jonathan Z. Long, Shingo Kajimura, Maria Cristina Zingaretti, Birgitte F. Vind, Hua Tu, Saverio Cinti, Kurt Højlund, Steven P. Gygi and Bruce M. Spiegelman

X-ray structures of LeuT in substrate-free outward-open and apo inward-open states pp. 469-474

Harini Krishnamurthy and Eric Gouaux

Transiting circumbinary planets Kepler-34 b and Kepler-35 b pp. 475-479

William F. Welsh, Jerome A. Orosz, Joshua A. Carter, Daniel C. Fabrycky, Eric B. Ford, Jack J. Lissauer, Andrej Prša, Samuel N. Quinn, Darin Ragozzine, Donald R. Short, Guillermo Torres, Joshua N. Winn, Laurance R. Doyle, Thomas Barclay, Natalie Batalha, Steven Bloemen, Erik Brugamyer, Lars A. Buchhave, Caroline Caldwell, Douglas A. Caldwell, Jessie L. Christiansen, David R. Ciardi, William D. Cochran, Michael Endl, Jonathan J. Fortney, Thomas N. Gautier, Ronald L. Gilliland, Michael R. Haas, Jennifer R. Hall, Matthew J. Holman, Andrew W. Howard, Steve B. Howell, Howard Isaacson, Jon M. Jenkins, Todd C. Klaus, David W. Latham, Jie Li, Geoffrey W. Marcy, Tsevi Mazeh, Elisa V. Quintana, Paul Robertson, Avi Shporer, Jason H. Steffen, Gur Windmiller, David G. Koch and William J. Borucki

Generation of scaled protogalactic seed magnetic fields in laser-produced shock waves pp. 480-483

G. Gregori, A. Ravasio, C. D. Murphy, K. Schaar, A. Baird, A. R. Bell, A. Benuzzi-Mounaix, R. Bingham, C. Constantin, R. P. Drake, M. Edwards, E. T. Everson, C. D. Gregory, Y. Kuramitsu, W. Lau, J. Mithen, C. Niemann, H.-S. Park, B. A. Remington, B. Reville, A. P. L. Robinson, D. D. Ryutov, Y. Sakawa, S. Yang, N. C. Woolsey, M. Koenig and F. Miniati

Light-cone-like spreading of correlations in a quantum many-body system pp. 484-487

Marc Cheneau, Peter Barmettler, Dario Poletti, Manuel Endres, Peter Schauß, Takeshi Fukuhara, Christian Gross, Immanuel Bloch, Corinna Kollath and Stefan Kuhr

Atomic inner-shell X-ray laser at 1.46 nanometres pumped by an X-ray free-electron laser pp. 488-491

Nina Rohringer, Duncan Ryan, Richard A. London, Michael Purvis, Felicie Albert, James Dunn, John D. Bozek, Christoph Bostedt, Alexander Graf, Randal Hill, Stefan P. Hau-Riege and Jorge J. Rocca

Pathway complexity in supramolecular polymerization pp. 492-496

Peter A. Korevaar, Subi J. George, Albert J. Markvoort, Maarten M. J. Smulders, Peter A. J. Hilbers, Albert P. H. J. Schenning, Tom F. A. De Greef and E. W. Meijer

Social networks and cooperation in hunter-gatherers pp. 497-501

Coren L. Apicella, Frank W. Marlowe, James H. Fowler and Nicholas A. Christakis

Purkinje neuron synchrony elicits time-locked spiking in the cerebellar nuclei pp. 502-505

Abigail L. Person and Indira M. Raman

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing pp. 506-510

Li Ding, Timothy J. Ley, David E. Larson, Christopher A. Miller, Daniel C. Koboldt, John S. Welch, Julie K. Ritchey, Margaret A. Young, Tamara Lamprecht, Michael D. McLellan, Joshua F. McMichael, John W. Wallis, Charles Lu, Dong Shen, Christopher C. Harris, David J. Dooling, Robert S. Fulton, Lucinda L. Fulton, Ken Chen, Heather Schmidt, Joelle Kalicki-Veizer, Vincent J. Magrini, Lisa Cook, Sean D. McGrath, Tammi L. Vickery, Michael C. Wendl, Sharon Heath, Mark A. Watson, Daniel C. Link, Michael H. Tomasson, William D. Shannon, Jacqueline E. Payton, Shashikant Kulkarni, Peter Westervelt, Matthew J. Walter, Timothy A. Graubert, Elaine R. Mardis, Richard K. Wilson and John F. DiPersio

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis pp. 511-515

Congcong He, Michael C. Bassik, Viviana Moresi, Kai Sun, Yongjie Wei, Zhongju Zou, Zhenyi An, Joy Loh, Jill Fisher, Qihua Sun, Stanley Korsmeyer, Milton Packer, Herman I. May, Joseph A. Hill, Herbert W. Virgin, Christopher Gilpin, Guanghua Xiao, Rhonda Bassel-Duby, Philipp E. Scherer and Beth Levine

Multi-isotope imaging mass spectrometry quantifies stem cell division and metabolism pp. 516-519

Matthew L. Steinhauser, Andrew P. Bailey, Samuel E. Senyo, Christelle Guillermier, Todd S. Perlstein, Alex P. Gould, Richard T. Lee and Claude P. Lechene

Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia pp. 520-524

Duan-Sun Zhang, Valeria Piazza, Benjamin J. Perrin, Agnieszka K. Rzadzinska, J. Collin Poczatek, Mei Wang, Haydn M. Prosser, James M. Ervasti, David P. Corey and Claude P. Lechene

Molecular recognition of a single sphingolipid species by a protein’s transmembrane domain pp. 525-529

F.-Xabier Contreras, Andreas M. Ernst, Per Haberkant, Patrik Björkholm, Erik Lindahl, Başak Gönen, Christian Tischer, Arne Elofsson, Gunnar von Heijne, Christoph Thiele, Rainer Pepperkok, Felix Wieland and Britta Brügger

Structure of the carboxy-terminal region of a KCNH channel pp. 530-533

Tinatin I. Brelidze, Anne E. Carlson, Banumathi Sankaran and William N. Zagotta

Erratum: Selective killing of cancer cells by a small molecule targeting the stress response to ROS pp. 534-534

Lakshmi Raj, Takao Ide, Aditi U. Gurkar, Michael Foley, Monica Schenone, Xiaoyu Li, Nicola J. Tolliday, Todd R. Golub, Steven A. Carr, Alykhan F. Shamji, Andrew M. Stern, Anna Mandinova, Stuart L. Schreiber and Sam W. Lee

China: The gates are open pp. 535-537

Jane Qiu

Turning point: Rob McKay pp. 537-537

Virginia Gewin

Rock 'n' roll aliens pp. 540-540

Ralph Greco

2012, volume 481, articles 7381

Break down boundaries in climate research pp. 239-239

Paulo Artaxo

Pollutants key to climate fix pp. 245-246

Jeff Tollefson

Database tallies US emissions pp. 247-248

Jeff Tollefson

Evolution advocate turns to climate pp. 248-248

Susan Young

Murders unlikely to slow Iran’s nuclear efforts pp. 249-249

Sharon Weinberger

Russian drug law hinders clinical trials pp. 250-250

Alla Katsnelson

Gemini’s twin telescopes reboot pp. 251-251

Eric Hand

Finding philanthropy: Like it? Pay for it pp. 252-253

Jim Giles

Alternative funding: Sponsor my science pp. 254-255

Heidi Ledford

The price of charity pp. 260-260

Patrick Aebischer

Public health: Biodefence built on teamwork pp. 261-262

John Grabenstein

Fiction: Cosmic creation pp. 262-263

Pedro Ferreira

Antarctica: Scientists to the end pp. 264-264

Colin Martin

Rare day to highlight rare diseases pp. 265-265

Susan M. Gasser, James R. Lupski, Yann Le Cam and Olivier Menzel

Asian medicine: Small species at risk pp. 265-265

Vincent Nijman, K. Anne-Isole Nekaris and David P. Bickford

Call to split fisheries at home and abroad pp. 265-265

Ussif Sumaila

Investors unfazed by drug-patent expiry pp. 265-265

David Brindley, Brock Reeve and Chris Mason

Paul Mead Doty (1920–2011) pp. 266-266

Stuart A. Rice and Robert Haselkorn

A fresh twist for self-assembly pp. 268-269

Volker Schaller and Andreas R. Bausch

The path to retinoblastoma pp. 269-270

Julien Sage and Michael L. Cleary

A ratchet for protein complexity pp. 270-271

W. Ford Doolittle

Distant dwarfs pp. 272-273

Robert W. Schmidt

A division duet pp. 273-274

Curt Wittenberg

Stabilizers cause instability pp. 274-275

Jonathan Clayden

Reprogramming clinical outcome pp. 275-276

Geneviève Deblois and Vincent Giguère

Frontiers in biology pp. 277-277

Alex Eccleston, Angela Eggleston, Marie-Thérèse Heemels, Barbara Marte and Ursula Weiss

Inflammasomes in health and disease pp. 278-286

Till Strowig, Jorge Henao-Mejia, Eran Elinav and Richard Flavell

The DNA damage response and cancer therapy pp. 287-294

Christopher J. Lord and Alan Ashworth

The promise of induced pluripotent stem cells in research and therapy pp. 295-305

Daisy A. Robinton and George Q. Daley

Clonal evolution in cancer pp. 306-313

Mel Greaves and Carlo C. Maley

The contribution of bone to whole-organism physiology pp. 314-320

Gérard Karsenty and Mathieu Ferron

The Amazon basin in transition pp. 321-328

Eric A. Davidson, Alessandro C. de Araújo, Paulo Artaxo, Jennifer K. Balch, I. Foster Brown, Mercedes M. C. Bustamante, Michael T. Coe, Ruth S. DeFries, Michael Keller, Marcos Longo, J. William Munger, Wilfrid Schroeder, Britaldo S. Soares-Filho, Carlos M. Souza and Steven C. Wofsy

A novel retinoblastoma therapy from genomic and epigenetic analyses pp. 329-334

Jinghui Zhang, Claudia A. Benavente, Justina McEvoy, Jacqueline Flores-Otero, Li Ding, Xiang Chen, Anatoly Ulyanov, Gang Wu, Matthew Wilson, Jianmin Wang, Rachel Brennan, Michael Rusch, Amity L. Manning, Jing Ma, John Easton, Sheila Shurtleff, Charles Mullighan, Stanley Pounds, Suraj Mukatira, Pankaj Gupta, Geoff Neale, David Zhao, Charles Lu, Robert S. Fulton, Lucinda L. Fulton, Xin Hong, David J. Dooling, Kerri Ochoa, Clayton Naeve, Nicholas J. Dyson, Elaine R. Mardis, Armita Bahrami, David Ellison, Richard K. Wilson, James R. Downing and Michael A. Dyer

Structure of HDAC3 bound to co-repressor and inositol tetraphosphate pp. 335-340

Peter J. Watson, Louise Fairall, Guilherme M. Santos and John W. R. Schwabe

Gravitational detection of a low-mass dark satellite galaxy at cosmological distance pp. 341-343

S. Vegetti, D. J. Lagattuta, J. P. McKean, M. W. Auger, C. D. Fassnacht and L. V. E. Koopmans

Coherent singlet-triplet oscillations in a silicon-based double quantum dot pp. 344-347

B. M. Maune, M. G. Borselli, B. Huang, T. D. Ladd, P. W. Deelman, K. S. Holabird, A. A. Kiselev, I. Alvarado-Rodriguez, R. S. Ross, A. E. Schmitz, M. Sokolich, C. A. Watson, M. F. Gyure and A. T. Hunter

Reconfigurable self-assembly through chiral control of interfacial tension pp. 348-351

Thomas Gibaud, Edward Barry, Mark J. Zakhary, Mir Henglin, Andrew Ward, Yasheng Yang, Cristina Berciu, Rudolf Oldenbourg, Michael F. Hagan, Daniela Nicastro, Robert B. Meyer and Zvonimir Dogic

Kimberlite ascent by assimilation-fuelled buoyancy pp. 352-356

James K. Russell, Lucy A. Porritt, Yan Lavallée and Donald B. Dingwell

Recovery rates reflect distance to a tipping point in a living system pp. 357-359

Annelies J. Veraart, Elisabeth J. Faassen, Vasilis Dakos, Egbert H. van Nes, Miquel Lürling and Marten Scheffer

Evolution of increased complexity in a molecular machine pp. 360-364

Gregory C. Finnigan, Victor Hanson-Smith, Tom H. Stevens and Joseph W. Thornton

Global landscape of HIV–human protein complexes pp. 365-370

Stefanie Jäger, Peter Cimermancic, Natali Gulbahce, Jeffrey R. Johnson, Kathryn E. McGovern, Starlynn C. Clarke, Michael Shales, Gaelle Mercenne, Lars Pache, Kathy Li, Hilda Hernandez, Gwendolyn M. Jang, Shoshannah L. Roth, Eyal Akiva, John Marlett, Melanie Stephens, Iván D’Orso, Jason Fernandes, Marie Fahey, Cathal Mahon, Anthony J. O’Donoghue, Aleksandar Todorovic, John H. Morris, David A. Maltby, Tom Alber, Gerard Cagney, Frederic D. Bushman, John A. Young, Sumit K. Chanda, Wesley I. Sundquist, Tanja Kortemme, Ryan D. Hernandez, Charles S. Craik, Alma Burlingame, Andrej Sali, Alan D. Frankel and Nevan J. Krogan

Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection pp. 371-375

Stefanie Jäger, Dong Young Kim, Judd F. Hultquist, Keisuke Shindo, Rebecca S. LaRue, Eunju Kwon, Ming Li, Brett D. Anderson, Linda Yen, David Stanley, Cathal Mahon, Joshua Kane, Kathy Franks-Skiba, Peter Cimermancic, Alma Burlingame, Andrej Sali, Charles S. Craik, Reuben S. Harris, John D. Gross and Nevan J. Krogan

T-cell differentiation factor CBF-β regulates HIV-1 Vif-mediated evasion of host restriction pp. 376-379

Wenyan Zhang, Juan Du, Sean L. Evans, Yunkai Yu and Xiao-Fang Yu

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia pp. 380-384

Christian M. Metallo, Paulo A. Gameiro, Eric L. Bell, Katherine R. Mattaini, Juanjuan Yang, Karsten Hiller, Christopher M. Jewell, Zachary R. Johnson, Darrell J. Irvine, Leonard Guarente, Joanne K. Kelleher, Matthew G. Vander Heiden, Othon Iliopoulos and Gregory Stephanopoulos

Reductive carboxylation supports growth in tumour cells with defective mitochondria pp. 385-388

Andrew R. Mullen, William W. Wheaton, Eunsook S. Jin, Pei-Hsuan Chen, Lucas B. Sullivan, Tzuling Cheng, Youfeng Yang, W. Marston Linehan, Navdeep S. Chandel and Ralph J. DeBerardinis

Differential oestrogen receptor binding is associated with clinical outcome in breast cancer pp. 389-393

Caryn S. Ross-Innes, Rory Stark, Andrew E. Teschendorff, Kelly A. Holmes, H. Raza Ali, Mark J. Dunning, Gordon D. Brown, Ondrej Gojis, Ian O. Ellis, Andrew R. Green, Simak Ali, Suet-Feung Chin, Carlo Palmieri, Carlos Caldas and Jason S. Carroll

Natural killer cells act as rheostats modulating antiviral T cells pp. 394-398

Stephen N. Waggoner, Markus Cornberg, Liisa K. Selin and Raymond M. Welsh

Outreach: Field hospitality pp. 399-401

Lucas Laursen

A game of self-deceit pp. 404-404

Clayton Locke

2012, volume 481, articles 7380

Don't censor life-saving science pp. 115-115

Peter Palese

France 'imagines the unimaginable' pp. 121-122

Declan Butler

Greek science on the brink pp. 123-124

Alison Abbott

Disaster toll tallied pp. 124-125

Quirin Schiermeier

Rules tighten on use of antibiotics on farms pp. 125-125

Natasha Gilbert

Radio array starts work pp. 127-127

Eric Hand

US translational-science centre gets under way pp. 128-128

Meredith Wadman

Stem-cell research: Never say die pp. 130-133

Corie Lok

Research ethics: Zero tolerance pp. 134-136

David Cyranoski

Deadline 2015 pp. 137-138

Michael Jacobs

A market approach to saving the whales pp. 139-140

Christopher Costello, Steven Gaines and Leah R. Gerber

Conservation: Harpoons and heartstrings pp. 141-142

Philip Hoare

Energy: Curbing urban greed pp. 142-143

David Orr

Q&A: Maestro of the swarm pp. 144-144

Laura Spinney

A genomic network to monitor Earth pp. 145-145

Neil Davies, Dawn Field and The Genomic Observatories Network

Reduce urban flood vulnerability pp. 145-145

Alan D. Ziegler

India should exploit renewable energy pp. 145-145

Govindasamy Agoramoorthy

Latest MMR 'dispute' is a straw man pp. 145-145

Brian Deer

Leaping lizards and dinosaurs pp. 148-149

R. McNeill Alexander

Progenitors of type Ia supernovae pp. 149-150

Pilar Ruiz-Lapuente

Drugs to awaken a paternal gene pp. 151-152

Arthur L. Beaudet

Nanowire electronics comes of age pp. 152-153

Tomás Palacios

Limits of the power law pp. 153-154

Andrew M. Walker

Your face looks familiar pp. 154-155

Lars Chittka and Adrian Dyer

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia pp. 157-163

Jinghui Zhang, Li Ding, Linda Holmfeldt, Gang Wu, Sue L. Heatley, Debbie Payne-Turner, John Easton, Xiang Chen, Jianmin Wang, Michael Rusch, Charles Lu, Shann-Ching Chen, Lei Wei, J. Racquel Collins-Underwood, Jing Ma, Kathryn G. Roberts, Stanley B. Pounds, Anatoly Ulyanov, Jared Becksfort, Pankaj Gupta, Robert Huether, Richard W. Kriwacki, Matthew Parker, Daniel J. McGoldrick, David Zhao, Daniel Alford, Stephen Espy, Kiran Chand Bobba, Guangchun Song, Deqing Pei, Cheng Cheng, Stefan Roberts, Michael I. Barbato, Dario Campana, Elaine Coustan-Smith, Sheila A. Shurtleff, Susana C. Raimondi, Maria Kleppe, Jan Cools, Kristin A. Shimano, Michelle L. Hermiston, Sergei Doulatov, Kolja Eppert, Elisa Laurenti, Faiyaz Notta, John E. Dick, Giuseppe Basso, Stephen P. Hunger, Mignon L. Loh, Meenakshi Devidas, Brent Wood, Stuart Winter, Kimberley P. Dunsmore, Robert S. Fulton, Lucinda L. Fulton, Xin Hong, Christopher C. Harris, David J. Dooling, Kerri Ochoa, Kimberly J. Johnson, John C. Obenauer, William E. Evans, Ching-Hon Pui, Clayton W. Naeve, Timothy J. Ley, Elaine R. Mardis, Richard K. Wilson, James R. Downing and Charles G. Mullighan

An absence of ex-companion stars in the type Ia supernova remnant SNR 0509−67.5 pp. 164-166

Bradley E. Schaefer and Ashley Pagnotta

One or more bound planets per Milky Way star from microlensing observations pp. 167-169

A. Cassan, D. Kubas, J.-P. Beaulieu, M. Dominik, K. Horne, J. Greenhill, J. Wambsganss, J. Menzies, A. Williams, U. G. Jørgensen, A. Udalski, D. P. Bennett, M. D. Albrow, V. Batista, S. Brillant, J. A. R. Caldwell, A. Cole, Ch. Coutures, K. H. Cook, S. Dieters, D. Dominis Prester, J. Donatowicz, P. Fouqué, K. Hill, N. Kains, S. Kane, J.-B. Marquette, R. Martin, K. R. Pollard, K. C. Sahu, C. Vinter, D. Warren, B. Watson, M. Zub, T. Sumi, M. K. Szymański, M. Kubiak, R. Poleski, I. Soszynski, K. Ulaczyk, G. Pietrzyński and Ł. Wyrzykowski

Implementation of a Toffoli gate with superconducting circuits pp. 170-172

A. Fedorov, L. Steffen, M. Baur, M. P. da Silva and A. Wallraff

Charge order and three-site distortions in the Verwey structure of magnetite pp. 173-176

Mark S. Senn, Jon P. Wright and J. Paul Attfield

Modelling the rheology of MgO under Earth’s mantle pressure, temperature and strain rates pp. 177-180

Patrick Cordier, Jonathan Amodeo and Philippe Carrez

Tail-assisted pitch control in lizards, robots and dinosaurs pp. 181-184

Thomas Libby, Talia Y. Moore, Evan Chang-Siu, Deborah Li, Daniel J. Cohen, Ardian Jusufi and Robert J. Full

Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons pp. 185-189

Hsien-Sung Huang, John A. Allen, Angela M. Mabb, Ian F. King, Jayalakshmi Miriyala, Bonnie Taylor-Blake, Noah Sciaky, J. Walter Dutton, Hyeong-Min Lee, Xin Chen, Jian Jin, Arlene S. Bridges, Mark J. Zylka, Bryan L. Roth and Benjamin D. Philpot

A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells pp. 190-194

Kim J. Png, Nils Halberg, Mitsukuni Yoshida and Sohail F. Tavazoie

Ars2 maintains neural stem-cell identity through direct transcriptional activation of Sox2 pp. 195-198

Celia Andreu-Agullo, Thomas Maurin, Craig B. Thompson and Eric C. Lai

Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut pp. 199-203

Jörg H. Fritz, Olga Lucia Rojas, Nathalie Simard, Douglas D. McCarthy, Siegfried Hapfelmeier, Stephen Rubino, Susan J. Robertson, Mani Larijani, Jean Gosselin, Ivaylo I. Ivanov, Alberto Martin, Rafael Casellas, Dana J. Philpott, Stephen E. Girardin, Kathy D. McCoy, Andrew J. Macpherson, Christopher J. Paige and Jennifer L. Gommerman

Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation pp. 204-208

Li Zhang, Xiaojun Ding, Jixin Cui, Hao Xu, Jing Chen, Yi-Nan Gong, Liyan Hu, Yan Zhou, Jianning Ge, Qiuhe Lu, Liping Liu, She Chen and Feng Shao

Basic amino-acid side chains regulate transmembrane integrin signalling pp. 209-213

Chungho Kim, Thomas Schmidt, Eun-Gyung Cho, Feng Ye, Tobias S. Ulmer and Mark H. Ginsberg

Subnanometre-resolution structure of the intact Thermus thermophilus H+-driven ATP synthase pp. 214-218

Wilson C. Y. Lau and John L. Rubinstein

An unanticipated architecture of the 750-kDa α6β6 holoenzyme of 3-methylcrotonyl-CoA carboxylase pp. 219-223

Christine S. Huang, Peng Ge, Z. Hong Zhou and Liang Tong

Erratum: Thermalization and its mechanism for generic isolated quantum systems pp. 224-224

Marcos Rigol, Vanja Dunjko and Maxim Olshanii

How to stay afloat pp. 225-226

Jeffrey Perkel

Turning point: Saffron O'Neill pp. 227-227

Virginia Gewin

The driver pp. 230-230

Rahul Kanakia

2012, volume 481, articles 7379

Blue-sky bias should be brought down to Earth pp. 7-7

Daniel Sarewitz

Call to censor flu studies draws fire pp. 9-10

Heidi Ledford

Survey tunes in to dark energy pp. 10-11

Eric Hand

New year, new science pp. 12-12

Richard Van Noorden

A passion for science without barriers pp. 13-13

Adrianne Appel

Frontier experiments: Tough science pp. 14-17

Nicola Jones

Kepler’s surprise: The sounds of the stars pp. 18-19

Ron Cowen

The need for new physics pp. 24-24

John Ellis

Keep standards high pp. 25-25

Jerome Ravetz

Robotics: Morals and machines pp. 26-27

Braden Allenby

Q&A: The science showman pp. 28-28

Jascha Hoffman

Call to veto Brazil's forest-code revisions pp. 29-29

Alison G. Nazareno

Mauritius is putting conservation at risk pp. 29-29

F. B. Vincent Florens

Phoenix first to see silt grains on Mars pp. 29-29

Michael Velbel

Science and politics need more empathy pp. 29-29

Len Fisher

The final plunge pp. 32-33

Mark Morris

Bacteria collaborate to sense arsenic pp. 33-34

Christopher A. Voigt

How to hide in time pp. 35-36

Robert W. Boyd and Zhimin Shi

Behavioural effects of cocaine reversed pp. 36-37

Marina E. Wolf

A sensing array of radically coupled genetic ‘biopixels’ pp. 39-44

Arthur Prindle, Phillip Samayoa, Ivan Razinkov, Tal Danino, Lev S. Tsimring and Jeff Hasty

Antiparallel EmrE exports drugs by exchanging between asymmetric structures pp. 45-50

Emma A. Morrison, Gregory T. DeKoster, Supratik Dutta, Reza Vafabakhsh, Michael W. Clarkson, Arjun Bahl, Dorothee Kern, Taekjip Ha and Katherine A. Henzler-Wildman

A gas cloud on its way towards the supermassive black hole at the Galactic Centre pp. 51-54

S. Gillessen, R. Genzel, T. K. Fritz, E. Quataert, C. Alig, A. Burkert, J. Cuadra, F. Eisenhauer, O. Pfuhl, K. Dodds-Eden, C. F. Gammie and T. Ott

Fast core rotation in red-giant stars as revealed by gravity-dominated mixed modes pp. 55-57

Paul G. Beck, Josefina Montalban, Thomas Kallinger, Joris De Ridder, Conny Aerts, Rafael A. García, Saskia Hekker, Marc-Antoine Dupret, Benoit Mosser, Patrick Eggenberger, Dennis Stello, Yvonne Elsworth, Søren Frandsen, Fabien Carrier, Michel Hillen, Michael Gruberbauer, Jørgen Christensen-Dalsgaard, Andrea Miglio, Marica Valentini, Timothy R. Bedding, Hans Kjeldsen, Forrest R. Girouard, Jennifer R. Hall and Khadeejah A. Ibrahim

Polar methane accumulation and rainstorms on Titan from simulations of the methane cycle pp. 58-61

T. Schneider, S. D. B. Graves, E. L. Schaller and M. E. Brown

Demonstration of temporal cloaking pp. 62-65

Moti Fridman, Alessandro Farsi, Yoshitomo Okawachi and Alexander L. Gaeta

Changing Arctic Ocean freshwater pathways pp. 66-70

James Morison, Ron Kwok, Cecilia Peralta-Ferriz, Matt Alkire, Ignatius Rigor, Roger Andersen and Mike Steele

Reversal of cocaine-evoked synaptic potentiation resets drug-induced adaptive behaviour pp. 71-75

Vincent Pascoli, Marc Turiault and Christian Lüscher

Modulation of TRPA1 thermal sensitivity enables sensory discrimination in Drosophila pp. 76-80

Kyeongjin Kang, Vincent C. Panzano, Elaine C. Chang, Lina Ni, Alexandra M. Dainis, Adam M. Jenkins, Kimberly Regna, Marc A. T. Muskavitch and Paul A. Garrity

Antibody-based protection against HIV infection by vectored immunoprophylaxis pp. 81-84

Alejandro B. Balazs, Joyce Chen, Christin M. Hong, Dinesh S. Rao, Lili Yang and David Baltimore

Interactions between cancer stem cells and their niche govern metastatic colonization pp. 85-89

Ilaria Malanchi, Albert Santamaria-Martínez, Evelyn Susanto, Hong Peng, Hans-Anton Lehr, Jean-Francois Delaloye and Joerg Huelsken

FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas pp. 90-93

Shanshan Duan, Lukas Cermak, Julia K. Pagan, Mario Rossi, Cinzia Martinengo, Paola Francia di Celle, Bjoern Chapuy, Margaret Shipp, Roberto Chiarle and Michele Pagano

Open structure of the Ca2+ gating ring in the high-conductance Ca2+-activated K+ channel pp. 94-97

Peng Yuan, Manuel D. Leonetti, Yichun Hsiung and Roderick MacKinnon

Structure of a methyl-coenzyme M reductase from Black Sea mats that oxidize methane anaerobically pp. 98-101

Seigo Shima, Martin Krueger, Tobias Weinert, Ulrike Demmer, Jörg Kahnt, Rudolf K. Thauer and Ulrich Ermler

Women in business: Finding a way in pp. 103-105

Virginia Gewin

Turning point: Tiago Branco pp. 105-105

Virginia Gewin

1-9-4-blue-3-7-2-6-gamma-tetrahedron pp. 108-108

Ian Randal Strock