Staphylococcus δ-toxin induces allergic skin disease by activating mast cells

Yuumi Nakamura, Jon Oscherwitz, Kemp B. Cease, Susana M. Chan, Raul Muñoz-Planillo, Mizuho Hasegawa, Amer E. Villaruz, Gordon Y. C. Cheung, Martin J. McGavin, Jeffrey B. Travers, Michael Otto, Naohiro Inohara and Gabriel Núñez ()
Additional contact information
Yuumi Nakamura: University of Michigan Medical School
Jon Oscherwitz: University of Michigan Medical School
Kemp B. Cease: University of Michigan Medical School
Susana M. Chan: University of Michigan Medical School
Raul Muñoz-Planillo: University of Michigan Medical School
Mizuho Hasegawa: University of Michigan Medical School
Amer E. Villaruz: Laboratory of Human Bacterial Pathogenesis, National Institute of Allergy and Infectious Diseases, US National Institutes of Health
Gordon Y. C. Cheung: Laboratory of Human Bacterial Pathogenesis, National Institute of Allergy and Infectious Diseases, US National Institutes of Health
Martin J. McGavin: and Centre for Human Immunology, Western University, University of Western Ontario, London, Ontario, N6A 5C1, Canada
Jeffrey B. Travers: Indiana University School of Medicine
Michael Otto: Laboratory of Human Bacterial Pathogenesis, National Institute of Allergy and Infectious Diseases, US National Institutes of Health
Naohiro Inohara: University of Michigan Medical School
Gabriel Núñez: University of Michigan Medical School

Nature, 2013, vol. 503, issue 7476, 397-401

Abstract: Staphylococcus aureus δ-toxin is an inducer of mast cell degranulation in mice and is important for promoting inflammatory skin disease.

Date: 2013
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DOI: 10.1038/nature12655

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