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2020, volume 577, articles 7792

The gut microbiome pp. S5-S5

Herb Brody

The hunt for a healthy microbiome pp. S6-S8

Michael Eisenstein

Author Correction: Super-Mendelian inheritance mediated by CRISPR–Cas9 in the female mouse germline pp. E8-E8

Hannah A. Grunwald, Valentino M. Gantz, Gunnar Poplawski, Xiang-Ru S. Xu, Ethan Bier and Kimberly L. Cooper

Homing in on the molecules from microbes pp. S9-S9

Andrew Scott

Author Correction: Global glacier mass changes and their contributions to sea-level rise from 1961 to 2016 pp. E9-E9

M. Zemp, M. Huss, E. Thibert, N. Eckert, R. McNabb, J. Huber, M. Barandun, H. Machguth, S. U. Nussbaumer, I. Gärtner-Roer, L. Thomson, F. Paul, F. Maussion, S. Kutuzov and J. G. Cogley

Publisher Correction: Progenitors from the central nervous system drive neurogenesis in cancer pp. E10-E10

Philippe Mauffrey, Nicolas Tchitchek, Vilma Barroca, Alexis-Pierre Bemelmans, Virginie Firlej, Yves Allory, Paul-Henri Roméo and Claire Magnon

The complex relationship between drugs and the microbiome pp. S10-S11

Neil Savage

Could a bacteria-stuffed pill cure autoimmune diseases? pp. S12-S13

Eric Bender

Could the gut microbiome be linked to autism? pp. S14-S15

Elizabeth Svoboda

Fighting cancer with microbes pp. S16-S18

Elie Dolgin

Rich data sets could end costly drug discovery pp. S19-S19

Eran Segal

Therapeutic microbes to tackle disease pp. S20-S22

Claire Ainsworth

Diet should be a tool for researchers, not a treatment pp. S23-S23

Peter J. Turnbaugh

Highlights from studies on the gut microbiome pp. S24-S25

Liam Drew

Remember what science owes to child refugees pp. 599-599

Georgina Ferry

China coronavirus: Six questions scientists are asking pp. 605-607

Ewen Callaway and David Cyranoski

This scientist hopes to test coronavirus drugs on animals in locked-down Wuhan pp. 607-607

David Cyranoski

Brexit is happening: what does it mean for science? pp. 608-608

Elizabeth Gibney

The battle for ethical AI at the world’s biggest machine-learning conference pp. 609-609

Elizabeth Gibney

The race to decipher how climate change influenced Australia’s record fires pp. 610-612

Nicky Phillips and Bianca Nogrady

Isaac Asimov: centenary of the great explainer pp. 614-616

David Leslie

Emissions – the ‘business as usual’ story is misleading pp. 618-620

Zeke Hausfather and Glen Peters

UK chief scientific adviser on swift research visas post-Brexit pp. 622-622

Patrick Vallance

Innovative plant breeding could deliver crop revolution pp. 622-622

Sven Anders, Ashwani Pareek, Sneh L. Singla-Pareek, Kapuganti Jagadis Gupta and Christine H. Foyer

Genentech was not the first biotech company pp. 622-622

William Bains

Catalexit: funds for science could suffer pp. 622-622

José M. Rojo

How the stress of fight or flight turns hair white pp. 623-624

Shayla A. Clark and Christopher D. Deppmann

Suspect that modulates the heartbeat is ensnared pp. 624-626

Xiaohan Wang and Richard W. Tsien

A milestone in the hunt for metallic hydrogen pp. 626-627

Serge Desgreniers

A watershed moment for protein structure prediction pp. 627-628

Mohammed AlQuraishi

Techniques converge to map the developing human heart at single-cell level pp. 629-630

Ragini Phansalkar and Kristy Red-Horse

Synchrotron infrared spectroscopic evidence of the probable transition to metal hydrogen pp. 631-635

Paul Loubeyre, Florent Occelli and Paul Dumas

Dualities and non-Abelian mechanics pp. 636-640

Michel Fruchart, Yujie Zhou and Vincenzo Vitelli

Fully hardware-implemented memristor convolutional neural network pp. 641-646

Peng Yao, Huaqiang Wu, Bin Gao, Jianshi Tang, Qingtian Zhang, Wenqiang Zhang, J. Joshua Yang and He Qian

Gram-scale bottom-up flash graphene synthesis pp. 647-651

Duy X. Luong, Ksenia V. Bets, Wala Ali Algozeeb, Michael G. Stanford, Carter Kittrell, Weiyin Chen, Rodrigo V. Salvatierra, Muqing Ren, Emily A. McHugh, Paul A. Advincula, Zhe Wang, Mahesh Bhatt, Hua Guo, Vladimir Mancevski, Rouzbeh Shahsavari, Boris I. Yakobson and James M. Tour

Redox-switchable carboranes for uranium capture and release pp. 652-655

Megan Keener, Camden Hunt, Timothy G. Carroll, Vladimir Kampel, Roman Dobrovetsky, Trevor W. Hayton and Gabriel Ménard

Lactonization as a general route to β-C(sp3)–H functionalization pp. 656-659

Zhe Zhuang and Jin-Quan Yu

Oceanic forcing of penultimate deglacial and last interglacial sea-level rise pp. 660-664

Peter U. Clark, Feng He, Nicholas R. Golledge, Jerry X. Mitrovica, Andrea Dutton, Jeremy S. Hoffman and Sarah Dendy

Ancient West African foragers in the context of African population history pp. 665-670

Mark Lipson, Isabelle Ribot, Swapan Mallick, Nadin Rohland, Iñigo Olalde, Nicole Adamski, Nasreen Broomandkhoshbacht, Ann Marie Lawson, Saioa López, Jonas Oppenheimer, Kristin Stewardson, Raymond Neba’ane Asombang, Hervé Bocherens, Neil Bradman, Brendan J. Culleton, Els Cornelissen, Isabelle Crevecoeur, Pierre Maret, Forka Leypey Mathew Fomine, Philippe Lavachery, Christophe Mbida Mindzie, Rosine Orban, Elizabeth Sawchuk, Patrick Semal, Mark G. Thomas, Wim Neer, Krishna R. Veeramah, Douglas J. Kennett, Nick Patterson, Garrett Hellenthal, Carles Lalueza-Fox, Scott MacEachern, Mary E. Prendergast and David Reich

A distributional code for value in dopamine-based reinforcement learning pp. 671-675

Will Dabney, Zeb Kurth-Nelson, Naoshige Uchida, Clara Kwon Starkweather, Demis Hassabis, Rémi Munos and Matthew Botvinick

Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells pp. 676-681

Bing Zhang, Sai Ma, Inbal Rachmin, Megan He, Pankaj Baral, Sekyu Choi, William A. Gonçalves, Yulia Shwartz, Eva M. Fast, Yiqun Su, Leonard I. Zon, Aviv Regev, Jason D. Buenrostro, Thiago M. Cunha, Isaac M. Chiu, David E. Fisher and Ya-Chieh Hsu

Host-mediated ubiquitination of a mycobacterial protein suppresses immunity pp. 682-688

Lin Wang, Juehui Wu, Jun Li, Hua Yang, Tianqi Tang, Haijiao Liang, Mianyong Zuo, Jie Wang, Haipeng Liu, Feng Liu, Jianxia Chen, Zhonghua Liu, Yang Wang, Cheng Peng, Xiangyang Wu, Ruijuan Zheng, Xiaochen Huang, Yajun Ran, Zihe Rao and Baoxue Ge

VEGF-C-driven lymphatic drainage enables immunosurveillance of brain tumours pp. 689-694

Eric Song, Tianyang Mao, Huiping Dong, Ligia Simoes Braga Boisserand, Salli Antila, Marcus Bosenberg, Kari Alitalo, Jean-Leon Thomas and Akiko Iwasaki

Mechanism of adrenergic CaV1.2 stimulation revealed by proximity proteomics pp. 695-700

Guoxia Liu, Arianne Papa, Alexander N. Katchman, Sergey I. Zakharov, Daniel Roybal, Jessica A. Hennessey, Jared Kushner, Lin Yang, Bi-Xing Chen, Alexander Kushnir, Katerina Dangas, Steven P. Gygi, Geoffrey S. Pitt, Henry M. Colecraft, Manu Ben-Johny, Marian Kalocsay and Steven O. Marx

Negative supercoil at gene boundaries modulates gene topology pp. 701-705

Yathish Jagadheesh Achar, Mohamood Adhil, Ramveer Choudhary, Nick Gilbert and Marco Foiani

Improved protein structure prediction using potentials from deep learning pp. 706-710

Andrew W. Senior, Richard Evans, John Jumper, James Kirkpatrick, Laurent Sifre, Tim Green, Chongli Qin, Augustin Žídek, Alexander W. R. Nelson, Alex Bridgland, Hugo Penedones, Stig Petersen, Karen Simonyan, Steve Crossan, Pushmeet Kohli, David T. Jones, David Silver, Koray Kavukcuoglu and Demis Hassabis

Structure of SAGA and mechanism of TBP deposition on gene promoters pp. 711-716

Gabor Papai, Alexandre Frechard, Olga Kolesnikova, Corinne Crucifix, Patrick Schultz and Adam Ben-Shem

Structure of the transcription coactivator SAGA pp. 717-720

Haibo Wang, Christian Dienemann, Alexandra Stützer, Henning Urlaub, Alan C. M. Cheung and Patrick Cramer

Five ‘power skills’ for becoming a team leader pp. 721-722

Sarah Groover and Ruth Gotian

Alone where seals bark in the mist pp. 724-724

Kendall Powell

2020, volume 577, articles 7791

Author Correction: Weak average liquid-cloud-water response to anthropogenic aerosols pp. E3-E5

Velle Toll, Matthew Christensen, Johannes Quaas and Nicolas Bellouin

Author Correction: Molecular architecture of lineage allocation and tissue organization in early mouse embryo pp. E6-E6

Guangdun Peng, Shengbao Suo, Guizhong Cui, Fang Yu, Ran Wang, Jun Chen, Shirui Chen, Zhiwen Liu, Guoyu Chen, Yun Qian, Patrick P. L. Tam, Jing-Dong J. Han and Naihe Jing

Publisher Correction: In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer pp. E7-E7

Milica Momcilovic, Anthony Jones, Sean T. Bailey, Christopher M. Waldmann, Rui Li, Jason T. Lee, Gihad Abdelhady, Adrian Gomez, Travis Holloway, Ernst Schmid, David Stout, Michael C. Fishbein, Linsey Stiles, Deepa V. Dabir, Steven M. Dubinett, Heather Christofk, Orian Shirihai, Carla M. Koehler, Saman Sadeghi and David B. Shackelford

Our best weapons against cancer are not magic bullets pp. 451-451

Vinay Prasad

How the fight over a Hawaii mega-telescope could change astronomy pp. 457-458

Alexandra Witze

Supercomputer scours fossil record for Earth’s hidden extinctions pp. 458-459

Ewen Callaway

Research on embryo-like structures struggles to win US government funding pp. 459-460

Nidhi Subbaraman

Stress, anxiety, harassment: huge survey reveals pressures of scientists’ working lives pp. 460-461

Alison Abbott

How ‘spooky’ is quantum physics? The answer could be incalculable pp. 461-462

Davide Castelvecchi

The chemists policing Earth’s atmosphere for rogue pollution pp. 464-466

Jane Palmer

Leveraging change: the power of peer pressure pp. 468-469

Thomas Dietz

Paris taught me how to do what is necessary to combat climate change pp. 470-471

Christiana Figueres

Grant lottery is bureaucratic short-cut pp. 472-472

Andrew Beattie

Climate change: how to pack a punch at meetings pp. 472-472

Charles Davis, Benjamin Goulet-Scott and Jason Beckfield

New virus in China requires international control effort pp. 472-472

Shan-Lu Liu

Grant lottery: don’t stall ideas and careers pp. 472-472

Howard Vindin

Human activities have changed the shapes of river deltas pp. 473-474

Nick van de Giesen

New predictors for immunotherapy responses sharpen our view of the tumour microenvironment pp. 474-476

Tullia C. Bruno

Large African herbivores have helped to repair their environment pp. 476-476

Andrew Mitchinson

Versatile strategy for making 2D materials pp. 477-478

Wei Sun Leong

Meet the relatives of our cellular ancestor pp. 478-479

Christa Schleper and Filipa L. Sousa

Signatures of self-organized criticality in an ultracold atomic gas pp. 481-486

S. Helmrich, A. Arias, G. Lochead, T. M. Wintermantel, M. Buchhold, S. Diehl and S. Whitlock

Fast two-qubit logic with holes in germanium pp. 487-491

N. W. Hendrickx, D. P. Franke, A. Sammak, G. Scappucci and M. Veldhorst

Conversion of non-van der Waals solids to 2D transition-metal chalcogenides pp. 492-496

Zhiguo Du, Shubin Yang, Songmei Li, Jun Lou, Shuqing Zhang, Shuai Wang, Bin Li, Yongji Gong, Li Song, Xiaolong Zou and Pulickel M. Ajayan

Antagonistic cooperativity between crystal growth modifiers pp. 497-501

Wenchuan Ma, James F. Lutsko, Jeffrey D. Rimer and Peter G. Vekilov

Superstructure control of first-cycle voltage hysteresis in oxygen-redox cathodes pp. 502-508

Robert A. House, Urmimala Maitra, Miguel A. Pérez-Osorio, Juan G. Lozano, Liyu Jin, James W. Somerville, Laurent C. Duda, Abhishek Nag, Andrew Walters, Ke-Jin Zhou, Matthew R. Roberts and Peter G. Bruce

Molecular tuning of CO2-to-ethylene conversion pp. 509-513

Fengwang Li, Arnaud Thevenon, Alonso Rosas-Hernández, Ziyun Wang, Yilin Li, Christine M. Gabardo, Adnan Ozden, Cao Thang Dinh, Jun Li, Yuhang Wang, Jonathan P. Edwards, Yi Xu, Christopher McCallum, Lizhi Tao, Zhi-Qin Liang, Mingchuan Luo, Xue Wang, Huihui Li, Colin P. O’Brien, Chih-Shan Tan, Dae-Hyun Nam, Rafael Quintero-Bermudez, Tao-Tao Zhuang, Yuguang C. Li, Zhiji Han, R. David Britt, David Sinton, Theodor Agapie, Jonas C. Peters and Edward H. Sargent

Global-scale human impact on delta morphology has led to net land area gain pp. 514-518

J. H. Nienhuis, A. D. Ashton, D. A. Edmonds, A. J. F. Hoitink, A. J. Kettner, J. C. Rowland and T. E. Törnqvist

Isolation of an archaeon at the prokaryote–eukaryote interface pp. 519-525

Hiroyuki Imachi, Masaru K. Nobu, Nozomi Nakahara, Yuki Morono, Miyuki Ogawara, Yoshihiro Takaki, Yoshinori Takano, Katsuyuki Uematsu, Tetsuro Ikuta, Motoo Ito, Yohei Matsui, Masayuki Miyazaki, Kazuyoshi Murata, Yumi Saito, Sanae Sakai, Chihong Song, Eiji Tasumi, Yuko Yamanaka, Takashi Yamaguchi, Yoichi Kamagata, Hideyuki Tamaki and Ken Takai

Nearest neighbours reveal fast and slow components of motor learning pp. 526-530

Sepp Kollmorgen, Richard H. R. Hahnloser and Valerio Mante

Decoding the development of the human hippocampus pp. 531-536

Suijuan Zhong, Wenyu Ding, Le Sun, Yufeng Lu, Hao Dong, Xiaoying Fan, Zeyuan Liu, Ruiguo Chen, Shu Zhang, Qiang Ma, Fuchou Tang, Qian Wu and Xiaoqun Wang

A developmental landscape of 3D-cultured human pre-gastrulation embryos pp. 537-542

Lifeng Xiang, Yu Yin, Yun Zheng, Yanping Ma, Yonggang Li, Zhigang Zhao, Junqiang Guo, Zongyong Ai, Yuyu Niu, Kui Duan, Jingjing He, Shuchao Ren, Dan Wu, Yun Bai, Zhouchun Shang, Xi Dai, Weizhi Ji and Tianqing Li

Microbiota-targeted maternal antibodies protect neonates from enteric infection pp. 543-548

Wen Zheng, Wenjing Zhao, Meng Wu, Xinyang Song, Florence Caro, Ximei Sun, Francesca Gazzaniga, Giuseppe Stefanetti, Sungwhan Oh, John J. Mekalanos and Dennis L. Kasper

B cells and tertiary lymphoid structures promote immunotherapy response pp. 549-555

Beth A. Helmink, Sangeetha M. Reddy, Jianjun Gao, Shaojun Zhang, Rafet Basar, Rohit Thakur, Keren Yizhak, Moshe Sade-Feldman, Jorge Blando, Guangchun Han, Vancheswaran Gopalakrishnan, Yuanxin Xi, Hao Zhao, Rodabe N. Amaria, Hussein A. Tawbi, Alex P. Cogdill, Wenbin Liu, Valerie S. LeBleu, Fernanda G. Kugeratski, Sapna Patel, Michael A. Davies, Patrick Hwu, Jeffrey E. Lee, Jeffrey E. Gershenwald, Anthony Lucci, Reetakshi Arora, Scott Woodman, Emily Z. Keung, Pierre-Olivier Gaudreau, Alexandre Reuben, Christine N. Spencer, Elizabeth M. Burton, Lauren E. Haydu, Alexander J. Lazar, Roberta Zapassodi, Courtney W. Hudgens, Deborah A. Ledesma, SuFey Ong, Michael Bailey, Sarah Warren, Disha Rao, Oscar Krijgsman, Elisa A. Rozeman, Daniel Peeper, Christian U. Blank, Ton N. Schumacher, Lisa H. Butterfield, Monika A. Zelazowska, Kevin M. McBride, Raghu Kalluri, James Allison, Florent Petitprez, Wolf Herman Fridman, Catherine Sautès-Fridman, Nir Hacohen, Katayoun Rezvani, Padmanee Sharma, Michael T. Tetzlaff, Linghua Wang and Jennifer A. Wargo

B cells are associated with survival and immunotherapy response in sarcoma pp. 556-560

Florent Petitprez, Aurélien Reyniès, Emily Z. Keung, Tom Wei-Wu Chen, Cheng-Ming Sun, Julien Calderaro, Yung-Ming Jeng, Li-Ping Hsiao, Laetitia Lacroix, Antoine Bougoüin, Marco Moreira, Guillaume Lacroix, Ivo Natario, Julien Adam, Carlo Lucchesi, Yec′han Laizet, Maud Toulmonde, Melissa A. Burgess, Vanessa Bolejack, Denise Reinke, Khalid M. Wani, Wei-Lien Wang, Alexander J. Lazar, Christina L. Roland, Jennifer A. Wargo, Antoine Italiano, Catherine Sautès-Fridman, Hussein A. Tawbi and Wolf H. Fridman

Tertiary lymphoid structures improve immunotherapy and survival in melanoma pp. 561-565

Rita Cabrita, Martin Lauss, Adriana Sanna, Marco Donia, Mathilde Skaarup Larsen, Shamik Mitra, Iva Johansson, Bengt Phung, Katja Harbst, Johan Vallon-Christersson, Alison Schoiack, Kristina Lövgren, Sarah Warren, Karin Jirström, Håkan Olsson, Kristian Pietras, Christian Ingvar, Karolin Isaksson, Dirk Schadendorf, Henrik Schmidt, Lars Bastholt, Ana Carneiro, Jennifer A. Wargo, Inge Marie Svane and Göran Jönsson

TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1 pp. 566-571

Jie Su, Sophie M. Morgani, Charles J. David, Qiong Wang, Ekrem Emrah Er, Yun-Han Huang, Harihar Basnet, Yilong Zou, Weiping Shu, Rajesh K. Soni, Ronald C. Hendrickson, Anna-Katerina Hadjantonakis and Joan Massagué

An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity pp. 572-575

Januka S. Athukoralage, Stephen A. McMahon, Changyi Zhang, Sabine Grüschow, Shirley Graham, Mart Krupovic, Rachel J. Whitaker, Tracey M. Gloster and Malcolm F. White

H2A.Z facilitates licensing and activation of early replication origins pp. 576-581

Haizhen Long, Liwei Zhang, Mengjie Lv, Zengqi Wen, Wenhao Zhang, Xiulan Chen, Peitao Zhang, Tongqing Li, Luyuan Chang, Caiwei Jin, Guozhao Wu, Xi Wang, Fuquan Yang, Jianfeng Pei, Ping Chen, Raphael Margueron, Haiteng Deng, Mingzhao Zhu and Guohong Li

Exposing the secret life of whales at the World Economic Forum pp. 583-584

Nick Pyenson

Technologies to watch in 2020 pp. 585-587

Esther Landhuis

Sharing space with 34 million dead insects pp. 590-590

Amber Dance

2020, volume 577, articles 7790

From plastic toys to Industry 4.0: How Taiwan is using science to upgrade its manufacturing pp. S1-S3

Sarah O’Meara

Global problems need social science pp. 295-295

Hetan Shah

Canadian universities mourn researchers who died in Iran plane crash pp. 301-302

Nidhi Subbaraman

Chinese academics who work abroad are slower to win major honour pp. 302-303

Hepeng Jia

SpaceX tests black satellite to reduce ‘megaconstellation’ threat to astronomy pp. 303-303

Alexandra Witze

‘Deathly silent’: Ecologist describes Australian wildfires’ devastating aftermath pp. 304-304

Dyani Lewis

World’s largest radio telescope needs to hit US$1-billion target pp. 305-305

Sarah Wild

Not so hot: US data suggest human bodies are cooling down pp. 306-306

Ewen Callaway

The kill-switch for CRISPR that could make gene-editing safer pp. 308-310

Elie Dolgin

The dangers of fringe economics in government pp. 311-313

Ehsan Masood

Data judo, the interconnected self, and the dystopia in Silicon Valley: Books in brief pp. 313-313

Barbara Kiser

Time for the Human Screenome Project pp. 314-317

Byron Reeves, Thomas Robinson and Nilam Ram

Rooibos settlement omits other marginalized people pp. 318-318

Sarah Ives, Rachel Wynberg and Graham Dutfield

Kurdistan: instability wrecks research and education pp. 318-318

Ebrahim Karimi

Futures: Print lover mourns the loss of Nature’s sci-fi stories pp. 318-318

Joseph Moore

Top priority for Sahel? A zero-carbon world pp. 318-318

Keir Philip

Malaria-carrying mosquitoes get a leg up on insecticides pp. 319-320

Flaminia Catteruccia

Evolution of circuits for machine learning pp. 320-321

Cyrus F. Hirjibehedin

An immune-cell signature marks the brain in Alzheimer’s disease pp. 322-323

Michael T. Heneka

Platelets have a dangerous hold over immune cells in cardiovascular disease pp. 323-324

Filip K. Swirski

Transparent crystals with ultrahigh piezoelectricity pp. 325-326

Jurij Koruza

The arms race between bacteria and their phage foes pp. 327-336

Hannah G. Hampton, Bridget N. J. Watson and Peter C. Fineran

A population of dust-enshrouded objects orbiting the Galactic black hole pp. 337-340

Anna Ciurlo, Randall D. Campbell, Mark R. Morris, Tuan Do, Andrea M. Ghez, Aurélien Hees, Breann N. Sitarski, Kelly Kosmo O’Neil, Devin S. Chu, Gregory D. Martinez, Smadar Naoz and Alexander P. Stephan

Classification with a disordered dopant-atom network in silicon pp. 341-345

Tao Chen, Jeroen van Gelder, Bram van de Ven, Sergey V. Amitonov, Bram de Wilde, Hans-Christian Ruiz Euler, Hajo Broersma, Peter A. Bobbert, Floris A. Zwanenburg and Wilfred G. van der Wiel

Direct thermal neutron detection by the 2D semiconductor 6LiInP2Se6 pp. 346-349

Daniel G. Chica, Yihui He, Kyle M. McCall, Duck Young Chung, Rahmi O. Pak, Giancarlo Trimarchi, Zhifu Liu, Patrick M. De Lurgio, Bruce W. Wessels and Mercouri G. Kanatzidis

Transparent ferroelectric crystals with ultrahigh piezoelectricity pp. 350-354

Chaorui Qiu, Bo Wang, Nan Zhang, Shujun Zhang, Jinfeng Liu, David Walker, Yu Wang, Hao Tian, Thomas R. Shrout, Zhuo Xu, Long-Qing Chen and Fei Li

Archimedean lattices emerge in template-directed eutectic solidification pp. 355-358

Ashish A. Kulkarni, Erik Hanson, Runyu Zhang, Katsuyo Thornton and Paul V. Braun

Design and synthesis of multigrain nanocrystals via geometric misfit strain pp. 359-363

Myoung Hwan Oh, Min Gee Cho, Dong Young Chung, Inchul Park, Youngwook Paul Kwon, Colin Ophus, Dokyoon Kim, Min Gyu Kim, Beomgyun Jeong, X. Wendy Gu, Jinwoung Jo, Ji Mun Yoo, Jaeyoung Hong, Sara McMains, Kisuk Kang, Yung-Eun Sung, A. Paul Alivisatos and Taeghwan Hyeon

Importance and vulnerability of the world’s water towers pp. 364-369

W. W. Immerzeel, A. F. Lutz, M. Andrade, A. Bahl, H. Biemans, T. Bolch, S. Hyde, S. Brumby, B. J. Davies, A. C. Elmore, A. Emmer, M. Feng, A. Fernández, U. Haritashya, J. S. Kargel, M. Koppes, P. D. A. Kraaijenbrink, A. V. Kulkarni, P. A. Mayewski, S. Nepal, P. Pacheco, T. H. Painter, F. Pellicciotti, H. Rajaram, S. Rupper, A. Sinisalo, A. B. Shrestha, D. Viviroli, Y. Wada, C. Xiao, T. Yao and J. E. M. Baillie

Ocean acidification does not impair the behaviour of coral reef fishes pp. 370-375

Timothy D. Clark, Graham D. Raby, Dominique G. Roche, Sandra A. Binning, Ben Speers-Roesch, Fredrik Jutfelt and Josefin Sundin

A sensory appendage protein protects malaria vectors from pyrethroids pp. 376-380

Victoria A. Ingham, Amalia Anthousi, Vassilis Douris, Nicholas J. Harding, Gareth Lycett, Marion Morris, John Vontas and Hilary Ranson

Last appearance of Homo erectus at Ngandong, Java, 117,000–108,000 years ago pp. 381-385

Yan Rizal, Kira E. Westaway, Yahdi Zaim, Gerrit D. van den Bergh, E. Arthur Bettis, Michael J. Morwood, O. Frank Huffman, Rainer Grün, Renaud Joannes-Boyau, Richard M. Bailey, Sidarto, Michael C. Westaway, Iwan Kurniawan, Mark W. Moore, Michael Storey, Fachroel Aziz, Suminto, Jian-xin Zhao, Aswan, Maija E. Sipola, Roy Larick, John-Paul Zonneveld, Robert Scott, Shelby Putt and Russell L. Ciochon

Cortical pattern generation during dexterous movement is input-driven pp. 386-391

Britton A. Sauerbrei, Jian-Zhong Guo, Jeremy D. Cohen, Matteo Mischiati, Wendy Guo, Mayank Kabra, Nakul Verma, Brett Mensh, Kristin Branson and Adam W. Hantman

The emergence of transcriptional identity in somatosensory neurons pp. 392-398

Nikhil Sharma, Kali Flaherty, Karina Lezgiyeva, Daniel E. Wagner, Allon M. Klein and David D. Ginty

Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s disease pp. 399-404

David Gate, Naresha Saligrama, Olivia Leventhal, Andrew C. Yang, Michael S. Unger, Jinte Middeldorp, Kelly Chen, Benoit Lehallier, Divya Channappa, Mark B. Los Santos, Alisha McBride, John Pluvinage, Fanny Elahi, Grace Kyin-Ye Tam, Yongha Kim, Michael Greicius, Anthony D. Wagner, Ludwig Aigner, Douglas R. Galasko, Mark M. Davis and Tony Wyss-Coray

An acute immune response underlies the benefit of cardiac stem cell therapy pp. 405-409

Ronald J. Vagnozzi, Marjorie Maillet, Michelle A. Sargent, Hadi Khalil, Anne Katrine Z. Johansen, Jennifer A. Schwanekamp, Allen J. York, Vincent Huang, Matthias Nahrendorf, Sakthivel Sadayappan and Jeffery D. Molkentin

Microbial bile acid metabolites modulate gut RORγ+ regulatory T cell homeostasis pp. 410-415

Xinyang Song, Ximei Sun, Sungwhan F. Oh, Meng Wu, Yanbo Zhang, Wen Zheng, Naama Geva-Zatorsky, Ray Jupp, Diane Mathis, Christophe Benoist and Dennis L. Kasper

A GPR174–CCL21 module imparts sexual dimorphism to humoral immunity pp. 416-420

Ruozhu Zhao, Xin Chen, Weiwei Ma, Jinyu Zhang, Jie Guo, Xiu Zhong, Jiacheng Yao, Jiahui Sun, Julian Rubinfien, Xuyu Zhou, Jianbin Wang and Hai Qi

Rapid non-uniform adaptation to conformation-specific KRAS(G12C) inhibition pp. 421-425

Jenny Y. Xue, Yulei Zhao, Jordan Aronowitz, Trang T. Mai, Alberto Vides, Besnik Qeriqi, Dongsung Kim, Chuanchuan Li, Elisa Stanchina, Linas Mazutis, Davide Risso and Piro Lito

FACT caught in the act of manipulating the nucleosome pp. 426-431

Yang Liu, Keda Zhou, Naifu Zhang, Hui Wei, Yong Zi Tan, Zhening Zhang, Bridget Carragher, Clinton S. Potter, Sheena D’Arcy and Karolin Luger

Activation of the GLP-1 receptor by a non-peptidic agonist pp. 432-436

Peishen Zhao, Yi-Lynn Liang, Matthew J. Belousoff, Giuseppe Deganutti, Madeleine M. Fletcher, Francis S. Willard, Michael G. Bell, Michael E. Christe, Kyle W. Sloop, Asuka Inoue, Tin T. Truong, Lachlan Clydesdale, Sebastian G. B. Furness, Arthur Christopoulos, Ming-Wei Wang, Laurence J. Miller, Christopher A. Reynolds, Radostin Danev, Patrick M. Sexton and Denise Wootten

What I learnt from trying out industry before graduate school pp. 437-438

Ty Tang

Eleven tips for working with large data sets pp. 439-440

Julian Nowogrodzki

Orderly desk, orderly mind pp. 442-442

Kendall Powell

2020, volume 577, articles 7789

Author Correction: Tumour lineage shapes BRCA-mediated phenotypes pp. E1-E1

Philip Jonsson, Chaitanya Bandlamudi, Michael L. Cheng, Preethi Srinivasan, Shweta S. Chavan, Noah D. Friedman, Ezra Y. Rosen, Allison L. Richards, Nancy Bouvier, S. Duygu Selcuklu, Craig M. Bielski, Wassim Abida, Diana Mandelker, Ozge Birsoy, Liying Zhang, Ahmet Zehir, Mark T. A. Donoghue, José Baselga, Kenneth Offit, Howard I. Scher, Eileen M. O’Reilly, Zsofia K. Stadler, Nikolaus Schultz, Nicholas D. Socci, Agnes Viale, Marc Ladanyi, Mark E. Robson, David M. Hyman, Michael F. Berger, David B. Solit and Barry S. Taylor

Author Correction: Superluminal motion of a relativistic jet in the neutron-star merger GW170817 pp. E2-E2

K. P. Mooley, A. T. Deller, O. Gottlieb, E. Nakar, G. Hallinan, S. Bourke, D. A. Frail, A. Horesh, A. Corsi and K. Hotokezaka

New Year’s resolution: one meeting-free week a quarter pp. 147-147

Heidi Rehm

The huge scientific effort to study Notre-Dame’s ashes pp. 153-154

Philip Ball

What CRISPR-baby prison sentences mean for research pp. 154-155

David Cyranoski

How one astronomer hears the Universe pp. 155-155

Elizabeth Gibney

Quest to use CRISPR against disease gains ground pp. 156-156

Heidi Ledford

The quest to decipher how the body’s cells sense touch pp. 158-160

Amber Dance

Navigational secrets of the desert ant pp. 162-163

William A. Foster

Twisted timelines of a double dystopia pp. 164-165

Liesbeth Venema

How to age well, a culinary journey, and why you’re not as gullible as you thought: Books in brief pp. 165-165

Barbara Kiser

Check for publication integrity before misconduct pp. 167-169

Andrew Grey, Mark J. Bolland, Alison Avenell, Andrew A. Klein and C. K. Gunsalus

Census: on paper, by governments, is still best pp. 170-170

Ciara Breathnach and Tiziana Margaria

The Amazon: biofuels plan will drive deforestation pp. 170-170

Lucas Ferrante and Philip Fearnside

Social media sows consensus in disturbance ecology pp. 170-170

Emily B. Graham and Stefan Krause

Sahel: governments must boost basic services pp. 170-170

Janani Vivekananda

A structurally unstable semiconductor stabilized and enhanced by strain pp. 171-172

Jian Shi

Long-term predator–prey cycles finally achieved in the lab pp. 172-173

Alan Hastings

The physics of ice skating pp. 173-174

Daniel Bonn

Brain states behind exploring and hunting revealed pp. 175-176

Ethan Scott

Not all fast radio bursts are created equal pp. 176-177

Matthew Bailes

A brief history of human disease genetics pp. 179-189

Melina Claussnitzer, Judy H. Cho, Rory Collins, Nancy J. Cox, Emmanouil T. Dermitzakis, Matthew E. Hurles, Sekar Kathiresan, Eimear E. Kenny, Cecilia M. Lindgren, Daniel G. MacArthur, Kathryn N. North, Sharon E. Plon, Heidi L. Rehm, Neil Risch, Charles N. Rotimi, Jay Shendure, Nicole Soranzo and Mark I. McCarthy

A repeating fast radio burst source localized to a nearby spiral galaxy pp. 190-194

B. Marcote, K. Nimmo, J. W. T. Hessels, S. P. Tendulkar, C. G. Bassa, Z. Paragi, A. Keimpema, M. Bhardwaj, R. Karuppusamy, V. M. Kaspi, C. J. Law, D. Michilli, K. Aggarwal, B. Andersen, A. M. Archibald, K. Bandura, G. C. Bower, P. J. Boyle, C. Brar, S. Burke-Spolaor, B. J. Butler, T. Cassanelli, P. Chawla, P. Demorest, M. Dobbs, E. Fonseca, U. Giri, D. C. Good, K. Gourdji, A. Josephy, A. Yu. Kirichenko, F. Kirsten, T. L. Landecker, D. Lang, T. J. W. Lazio, D. Z. Li, H.-H. Lin, J. D. Linford, K. Masui, J. Mena-Parra, A. Naidu, C. Ng, C. Patel, U.-L. Pen, Z. Pleunis, M. Rafiei-Ravandi, M. Rahman, A. Renard, P. Scholz, S. R. Siegel, K. M. Smith, I. H. Stairs, K. Vanderlinde and A. V. Zwaniga

Resonant microwave-mediated interactions between distant electron spins pp. 195-198

F. Borjans, X. G. Croot, X. Mi, M. J. Gullans and J. R. Petta

Synthesis and properties of free-standing monolayer amorphous carbon pp. 199-203

Chee-Tat Toh, Hongji Zhang, Junhao Lin, Alexander S. Mayorov, Yun-Peng Wang, Carlo M. Orofeo, Darim Badur Ferry, Henrik Andersen, Nurbek Kakenov, Zenglong Guo, Irfan Haider Abidi, Hunter Sims, Kazu Suenaga, Sokrates T. Pantelides and Barbaros Özyilmaz

Proton-assisted growth of ultra-flat graphene films pp. 204-208

Guowen Yuan, Dongjing Lin, Yong Wang, Xianlei Huang, Wang Chen, Xuedong Xie, Junyu Zong, Qian-Qian Yuan, Hang Zheng, Di Wang, Jie Xu, Shao-Chun Li, Yi Zhang, Jian Sun, Xiaoxiang Xi and Libo Gao

Strain engineering and epitaxial stabilization of halide perovskites pp. 209-215

Yimu Chen, Yusheng Lei, Yuheng Li, Yugang Yu, Jinze Cai, Ming-Hui Chiu, Rahul Rao, Yue Gu, Chunfeng Wang, Woojin Choi, Hongjie Hu, Chonghe Wang, Yang Li, Jiawei Song, Jingxin Zhang, Baiyan Qi, Muyang Lin, Zhuorui Zhang, Ahmad E. Islam, Benji Maruyama, Shadi Dayeh, Lain-Jong Li, Kesong Yang, Yu-Hwa Lo and Sheng Xu

Single-chain heteropolymers transport protons selectively and rapidly pp. 216-220

Tao Jiang, Aaron Hall, Marco Eres, Zahra Hemmatian, Baofu Qiao, Yun Zhou, Zhiyuan Ruan, Andrew D. Couse, William T. Heller, Haiyan Huang, Monica Olvera de la Cruz, Marco Rolandi and Ting Xu

Palaeoclimate evidence of vulnerable permafrost during times of low sea ice pp. 221-225

A. Vaks, A. J. Mason, S. F. M. Breitenbach, A. M. Kononov, A. V. Osinzev, M. Rosensaft, A. Borshevsky, O. S. Gutareva and G. M. Henderson

Long-term cyclic persistence in an experimental predator–prey system pp. 226-230

Bernd Blasius, Lars Rudolf, Guntram Weithoff, Ursula Gaedke and Gregor F. Fussmann

Internal state dynamics shape brainwide activity and foraging behaviour pp. 239-243

João C. Marques, Meng Li, Diane Schaak, Drew N. Robson and Jennifer M. Li

A bacteriophage nucleus-like compartment shields DNA from CRISPR nucleases pp. 244-248

Senén D. Mendoza, Eliza S. Nieweglowska, Sutharsan Govindarajan, Lina M. Leon, Joel D. Berry, Anika Tiwari, Vorrapon Chaikeeratisak, Joe Pogliano, David A. Agard and Joseph Bondy-Denomy

IL-17a promotes sociability in mouse models of neurodevelopmental disorders pp. 249-253

Michael Douglas Reed, Yeong Shin Yim, Ralf D. Wimmer, Hyunju Kim, Changhyeon Ryu, Gwyneth Margaret Welch, Matias Andina, Hunter Oren King, Ari Waisman, Michael M. Halassa, Jun R. Huh and Gloria B. Choi

Somatic inflammatory gene mutations in human ulcerative colitis epithelium pp. 254-259

Kosaku Nanki, Masayuki Fujii, Mariko Shimokawa, Mami Matano, Shingo Nishikori, Shoichi Date, Ai Takano, Kohta Toshimitsu, Yuki Ohta, Sirirat Takahashi, Shinya Sugimoto, Kazuhiro Ishimaru, Kenta Kawasaki, Yoko Nagai, Ryota Ishii, Kosuke Yoshida, Nobuo Sasaki, Toshifumi Hibi, Soichiro Ishihara, Takanori Kanai and Toshiro Sato

Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis pp. 260-265

Nobuyuki Kakiuchi, Kenichi Yoshida, Motoi Uchino, Takako Kihara, Kotaro Akaki, Yoshikage Inoue, Kenji Kawada, Satoshi Nagayama, Akira Yokoyama, Shuji Yamamoto, Minoru Matsuura, Takahiro Horimatsu, Tomonori Hirano, Norihiro Goto, Yasuhide Takeuchi, Yotaro Ochi, Yusuke Shiozawa, Yasunori Kogure, Yosaku Watatani, Yoichi Fujii, Soo Ki Kim, Ayana Kon, Keisuke Kataoka, Tetsuichi Yoshizato, Masahiro M. Nakagawa, Akinori Yoda, Yasuhito Nanya, Hideki Makishima, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Masashi Sanada, Eiji Sugihara, Taka-aki Sato, Takashi Maruyama, Hiroyuki Miyoshi, Makoto Mark Taketo, Jun Oishi, Ryosaku Inagaki, Yutaka Ueda, Shinya Okamoto, Hideaki Okajima, Yoshiharu Sakai, Takaki Sakurai, Hironori Haga, Seiichi Hirota, Hiroki Ikeuchi, Hiroshi Nakase, Hiroyuki Marusawa, Tsutomu Chiba, Osamu Takeuchi, Satoru Miyano, Hiroshi Seno and Seishi Ogawa

HBO1 is required for the maintenance of leukaemia stem cells pp. 266-270

Laura MacPherson, Juliana Anokye, Miriam M. Yeung, Enid Y. N. Lam, Yih-Chih Chan, Chen-Fang Weng, Paul Yeh, Kathy Knezevic, Miriam S. Butler, Annabelle Hoegl, Kah-Lok Chan, Marian L. Burr, Linden J. Gearing, Tracy Willson, Joy Liu, Jarny Choi, Yuqing Yang, Rebecca A. Bilardi, Hendrik Falk, Nghi Nguyen, Paul A. Stupple, Thomas S. Peat, Ming Zhang, Melanie Silva, Catalina Carrasco-Pozo, Vicky M. Avery, Poh Sim Khoo, Olan Dolezal, Matthew L. Dennis, Stewart Nuttall, Regina Surjadi, Janet Newman, Bin Ren, David J. Leaver, Yuxin Sun, Jonathan B. Baell, Oliver Dovey, George S. Vassiliou, Florian Grebien, Sarah-Jane Dawson, Ian P. Street, Brendon J. Monahan, Christopher J. Burns, Chunaram Choudhary, Marnie E. Blewitt, Anne K. Voss, Tim Thomas and Mark A. Dawson

Structural basis of DNA targeting by a transposon-encoded CRISPR–Cas system pp. 271-274

Tyler S. Halpin-Healy, Sanne E. Klompe, Samuel H. Sternberg and Israel S. Fernández

Structure of the human metapneumovirus polymerase phosphoprotein complex pp. 275-279

Junhua Pan, Xinlei Qian, Simon Lattmann, Abbas El Sahili, Tiong Han Yeo, Huan Jia, Tessa Cressey, Barbara Ludeke, Sarah Noton, Marian Kalocsay, Rachel Fearns and Julien Lescar

Thirteen tips for engaging with physicists, as told by a biologist pp. 281-283

Ken Kosik

Twelve tips for engaging with biologists, as told by a physicist pp. 283-284

Sarah Bohndiek

In his element pp. 286-286

Amber Dance

2020, volume 577, articles 7788

A toast to the error detectors pp. 9-9

Simine Vazire

Australian biobank repatriates hundreds of ‘legacy’ Indigenous blood samples pp. 11-12

Dyani Lewis

United States to fund gun-violence research after 20-year freeze pp. 12-12

Nidhi Subbaraman

Low-carbon, virtual science conference tries to recreate social buzz pp. 13-13

Alison Abbott

Russia joins race to make quantum dreams a reality pp. 14-14

Quirin Schiermeier

This AI researcher is trying to ward off a reproducibility crisis pp. 14-14

Elizabeth Gibney

The science events to watch for in 2020 pp. 15-16

Davide Castelvecchi

The super-cool materials that send heat to space pp. 18-20

XiaoZhi Lim

2020 in science and culture: Nature’s pick of the listings pp. 22-25

Nicola Jones

Drink more recycled wastewater pp. 26-28

Cecilia Tortajada and Pierre van Rensburg

The quest for top female academics — a search and destroy mission? pp. 29-29

Susanne Täuber

China’s different shades of greening pp. 29-29

Lele Shu and Zexuan Xu

Earthquake prediction: heed the signs and save lives pp. 29-29

Sergio Bertolucci, Francesco Mulargia and Domenico Giardini

Testosterone’s role in ovulation pp. 29-29

Rebecca Jordan-Young and Katrina Karkazis

Tuberculosis vaccine finds an improved route pp. 31-32

Samuel M. Behar and Chris Sassetti

Food for thought about manipulating gut bacteria pp. 32-34

Nathalie M. Delzenne and Laure B. Bindels

Infrared spectroscopy finally sees the light pp. 34-35

Andreas Barth

AI shows promise for breast cancer screening pp. 35-36

Etta D. Pisano

Galaxy cluster illuminates the cosmic dark ages pp. 36-37

Nina A. Hatch

Spectroscopic confirmation of a mature galaxy cluster at a redshift of 2 pp. 39-41

J. P. Willis, R. E. A. Canning, E. S. Noordeh, S. W. Allen, A. L. King, A. Mantz, R. G. Morris, S. A. Stanford and G. Brammer

Localization and delocalization of light in photonic moiré lattices pp. 42-46

Peng Wang, Yuanlin Zheng, Xianfeng Chen, Changming Huang, Yaroslav V. Kartashov, Lluis Torner, Vladimir V. Konotop and Fangwei Ye

Inverse transition of labyrinthine domain patterns in ferroelectric thin films pp. 47-51

Y. Nahas, S. Prokhorenko, J. Fischer, B. Xu, C. Carrétéro, S. Prosandeev, M. Bibes, S. Fusil, B. Dkhil, V. Garcia and L. Bellaiche

Field-resolved infrared spectroscopy of biological systems pp. 52-59

Ioachim Pupeza, Marinus Huber, Michael Trubetskov, Wolfgang Schweinberger, Syed A. Hussain, Christina Hofer, Kilian Fritsch, Markus Poetzlberger, Lenard Vamos, Ernst Fill, Tatiana Amotchkina, Kosmas V. Kepesidis, Alexander Apolonski, Nicholas Karpowicz, Vladimir Pervak, Oleg Pronin, Frank Fleischmann, Abdallah Azzeer, Mihaela Žigman and Ferenc Krausz

Atomic imaging of the edge structure and growth of a two-dimensional hexagonal ice pp. 60-63

Runze Ma, Duanyun Cao, Chongqin Zhu, Ye Tian, Jinbo Peng, Jing Guo, Ji Chen, Xin-Zheng Li, Joseph S. Francisco, Xiao Cheng Zeng, Li-Mei Xu, En-Ge Wang and Ying Jiang

Confinement of atomically defined metal halide sheets in a metal–organic framework pp. 64-68

Miguel I. Gonzalez, Ari B. Turkiewicz, Lucy E. Darago, Julia Oktawiec, Karen Bustillo, Fernande Grandjean, Gary J. Long and Jeffrey R. Long

The past and future of global river ice pp. 69-73

Xiao Yang, Tamlin M. Pavelsky and George H. Allen

Assessing progress towards sustainable development over space and time pp. 74-78

Zhenci Xu, Sophia N. Chau, Xiuzhi Chen, Jian Zhang, Yingjie Li, Thomas Dietz, Jinyan Wang, Julie A. Winkler, Fan Fan, Baorong Huang, Shuxin Li, Shaohua Wu, Anna Herzberger, Ying Tang, Dequ Hong, Yunkai Li and Jianguo Liu

The water lily genome and the early evolution of flowering plants pp. 79-84

Liangsheng Zhang, Fei Chen, Xingtan Zhang, Zhen Li, Yiyong Zhao, Rolf Lohaus, Xiaojun Chang, Wei Dong, Simon Y. W. Ho, Xing Liu, Aixia Song, Junhao Chen, Wenlei Guo, Zhengjia Wang, Yingyu Zhuang, Haifeng Wang, Xuequn Chen, Juan Hu, Yanhui Liu, Yuan Qin, Kai Wang, Shanshan Dong, Yang Liu, Shouzhou Zhang, Xianxian Yu, Qian Wu, Liangsheng Wang, Xueqing Yan, Yuannian Jiao, Hongzhi Kong, Xiaofan Zhou, Cuiwei Yu, Yuchu Chen, Fan Li, Jihua Wang, Wei Chen, Xinlu Chen, Qidong Jia, Chi Zhang, Yifan Jiang, Wanbo Zhang, Guanhua Liu, Jianyu Fu, Feng Chen, Hong Ma, Yves Peer and Haibao Tang

RGF1 controls root meristem size through ROS signalling pp. 85-88

Masashi Yamada, Xinwei Han and Philip N. Benfey

International evaluation of an AI system for breast cancer screening pp. 89-94

Scott Mayer McKinney, Marcin Sieniek, Varun Godbole, Jonathan Godwin, Natasha Antropova, Hutan Ashrafian, Trevor Back, Mary Chesus, Greg S. Corrado, Ara Darzi, Mozziyar Etemadi, Florencia Garcia-Vicente, Fiona J. Gilbert, Mark Halling-Brown, Demis Hassabis, Sunny Jansen, Alan Karthikesalingam, Christopher J. Kelly, Dominic King, Joseph R. Ledsam, David Melnick, Hormuz Mostofi, Lily Peng, Joshua Jay Reicher, Bernardino Romera-Paredes, Richard Sidebottom, Mustafa Suleyman, Daniel Tse, Kenneth C. Young, Jeffrey Fauw and Shravya Shetty

Prevention of tuberculosis in macaques after intravenous BCG immunization pp. 95-102

Patricia A. Darrah, Joseph J. Zeppa, Pauline Maiello, Joshua A. Hackney, Marc H. Wadsworth, Travis K. Hughes, Supriya Pokkali, Phillip A. Swanson, Nicole L. Grant, Mark A. Rodgers, Megha Kamath, Chelsea M. Causgrove, Dominick J. Laddy, Aurelio Bonavia, Danilo Casimiro, Philana Ling Lin, Edwin Klein, Alexander G. White, Charles A. Scanga, Alex K. Shalek, Mario Roederer, JoAnne L. Flynn and Robert A. Seder

Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease pp. 103-108

Najoua Lalaoui, Steven E. Boyden, Hirotsugu Oda, Geryl M. Wood, Deborah L. Stone, Diep Chau, Lin Liu, Monique Stoffels, Tobias Kratina, Kate E. Lawlor, Kristien J. M. Zaal, Patrycja M. Hoffmann, Nima Etemadi, Kristy Shield-Artin, Christine Biben, Wanxia Li Tsai, Mary D. Blake, Hye Sun Kuehn, Dan Yang, Holly Anderton, Natasha Silke, Laurens Wachsmuth, Lixin Zheng, Natalia Sampaio Moura, David B. Beck, Gustavo Gutierrez-Cruz, Amanda K. Ombrello, Gineth P. Pinto-Patarroyo, Andrew J. Kueh, Marco J. Herold, Cathrine Hall, Hongying Wang, Jae Jin Chae, Natalia I. Dmitrieva, Mark McKenzie, Amanda Light, Beverly K. Barham, Anne Jones, Tina M. Romeo, Qing Zhou, Ivona Aksentijevich, James C. Mullikin, Andrew J. Gross, Anthony K. Shum, Edwin D. Hawkins, Seth L. Masters, Michael J. Lenardo, Manfred Boehm, Sergio D. Rosenzweig, Manolis Pasparakis, Anne K. Voss, Massimo Gadina, Daniel L. Kastner and John Silke

A dominant autoinflammatory disease caused by non-cleavable variants of RIPK1 pp. 109-114

Panfeng Tao, Jinqiao Sun, Zheming Wu, Shihao Wang, Jun Wang, Wanjin Li, Heling Pan, Renkui Bai, Jiahui Zhang, Ying Wang, Pui Y. Lee, Wenjing Ying, Qinhua Zhou, Jia Hou, Wenjie Wang, Bijun Sun, Mi Yang, Danru Liu, Ran Fang, Huan Han, Zhaohui Yang, Xin Huang, Haibo Li, Natalie Deuitch, Yuan Zhang, Dilan Dissanayake, Katrina Haude, Kirsty McWalter, Chelsea Roadhouse, Jennifer J. MacKenzie, Ronald M. Laxer, Ivona Aksentijevich, Xiaomin Yu, Xiaochuan Wang, Junying Yuan and Qing Zhou

Metabolic heterogeneity confers differences in melanoma metastatic potential pp. 115-120

Alpaslan Tasdogan, Brandon Faubert, Vijayashree Ramesh, Jessalyn M. Ubellacker, Bo Shen, Ashley Solmonson, Malea M. Murphy, Zhimin Gu, Wen Gu, Misty Martin, Stacy Y. Kasitinon, Travis Vandergriff, Thomas P. Mathews, Zhiyu Zhao, Dirk Schadendorf, Ralph J. DeBerardinis and Sean J. Morrison

Impaired cell fate through gain-of-function mutations in a chromatin reader pp. 121-126

Liling Wan, Shasha Chong, Fan Xuan, Angela Liang, Xiaodong Cui, Leah Gates, Thomas S. Carroll, Yuanyuan Li, Lijuan Feng, Guochao Chen, Shu-Ping Wang, Michael V. Ortiz, Sara K. Daley, Xiaolu Wang, Hongwen Xuan, Alex Kentsis, Tom W. Muir, Robert G. Roeder, Haitao Li, Wei Li, Robert Tjian, Hong Wen and C. David Allis

Regulation of α-synuclein by chaperones in mammalian cells pp. 127-132

Björn M. Burmann, Juan A. Gerez, Irena Matečko-Burmann, Silvia Campioni, Pratibha Kumari, Dhiman Ghosh, Adam Mazur, Emelie E. Aspholm, Darius Šulskis, Magdalena Wawrzyniuk, Thomas Bock, Alexander Schmidt, Stefan G. D. Rüdiger, Roland Riek and Sebastian Hiller

Secrets to writing a winning grant pp. 133-135

Emily Sohn

A space for contemplation pp. 138-138

Josie Glausiusz