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2011, volume 472, articles 7344

End the wasteful tyranny of reviewer experiments pp. 391-391

Hidde Ploegh

Is FutureGen betting on the wrong rock? pp. 398-399

Jeff Tollefson

Astronomers mull merger of missions pp. 402-402

Eugenie Samuel Reich

California ponders cell-banking venture pp. 403-403

Erika Check Hayden

Ancient DNA: Curse of the Pharaoh's DNA pp. 404-406

Jo Marchant

Shake-up time for Japanese seismology pp. 407-409

Robert J. Geller

The rise of people power pp. 410-411

Roger Chafe, Karen B. Born, Arthur S. Slutsky and Andreas Laupacis

Climate change: Lands' End to the Arctic pp. 413-414

Henry Pollack

Fiction: Reconstituted Edens pp. 414-415

Emma Marris

Psychology: The empathy gap pp. 416-416

Stephanie Preston

Art: Blurring the boundaries pp. 417-417

Deborah Dixon, Harriet Hawkins and Mrill Ingram

'No' to ban on stem-cell patents pp. 418-418

Austin Smith

'Plan B' for X-ray astronomy pp. 418-418

Martin Elvis

Bio-PIN could cut biobanking risks pp. 418-418

J. J. Nietfeld and Jan-Eric Litton

Arab world needs its science diaspora pp. 418-418

Hilal A. Lashuel and Wael K. Al-Delaimy

Lithosphere today pp. 420-421

George Zandt and Peter Reiners

A helping hand against autoimmunity pp. 421-422

Anton M. Jetten

Colour without colourants pp. 423-424

Paul V. Braun

Large-scale cooperation pp. 424-425

Amanda M. Seed and Keith Jensen

Polymer networks take a bow pp. 425-426

Wilhelm T. S. Huck

A new spin on the first stars pp. 426-427

Jason Tumlinson

Sleepy neurons? pp. 427-428

Christopher S. Colwell

On the role of the Agulhas system in ocean circulation and climate pp. 429-436

Lisa M. Beal, Wilhelmus P. M. De Ruijter, Arne Biastoch and Rainer Zahn

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction pp. 437-442

João Peça, Cátia Feliciano, Jonathan T. Ting, Wenting Wang, Michael F. Wells, Talaignair N. Venkatraman, Christopher D. Lascola, Zhanyan Fu and Guoping Feng

Local sleep in awake rats pp. 443-447

Vladyslav V. Vyazovskiy, Umberto Olcese, Erin C. Hanlon, Yuval Nir, Chiara Cirelli and Giulio Tononi

Structure and mechanism of the chromatin remodelling factor ISW1a pp. 448-453

Kazuhiro Yamada, Timothy D. Frouws, Brigitte Angst, Daniel J. Fitzgerald, Carl DeLuca, Kyoko Schimmele, David F. Sargent and Timothy J. Richmond

Imprints of fast-rotating massive stars in the Galactic Bulge pp. 454-457

Cristina Chiappini, Urs Frischknecht, Georges Meynet, Raphael Hirschi, Beatriz Barbuy, Marco Pignatari, Thibaut Decressin and André Maeder

Superconductor–insulator transition in La2 − xSr x CuO4 at the pair quantum resistance pp. 458-460

A. T. Bollinger, G. Dubuis, J. Yoon, D. Pavuna, J. Misewich and I. Božović

Continuing Colorado plateau uplift by delamination-style convective lithospheric downwelling pp. 461-465

A. Levander, B. Schmandt, M. S. Miller, K. Liu, K. E. Karlstrom, R. S. Crow, C.-T. A. Lee and E. D. Humphreys

Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation pp. 466-470

Amar Sahay, Kimberly N. Scobie, Alexis S. Hill, Colin M. O'Carroll, Mazen A. Kheirbek, Nesha S. Burghardt, André A. Fenton, Alex Dranovsky and René Hen

Activation of the innate immune receptor Dectin-1 upon formation of a ‘phagocytic synapse’ pp. 471-475

Helen S. Goodridge, Christopher N. Reyes, Courtney A. Becker, Tamiko R. Katsumoto, Jun Ma, Andrea J. Wolf, Nandita Bose, Anissa S. H. Chan, Andrew S. Magee, Michael E. Danielson, Arthur Weiss, John P. Vasilakos and David M. Underhill

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS pp. 476-480

A. Phillip West, Igor E. Brodsky, Christoph Rahner, Dong Kyun Woo, Hediye Erdjument-Bromage, Paul Tempst, Matthew C. Walsh, Yongwon Choi, Gerald S. Shadel and Sankar Ghosh

A diverse range of gene products are effectors of the type I interferon antiviral response pp. 481-485

John W. Schoggins, Sam J. Wilson, Maryline Panis, Mary Y. Murphy, Christopher T. Jones, Paul Bieniasz and Charles M. Rice

Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity pp. 486-490

Jun R. Huh, Monica W. L. Leung, Pengxiang Huang, Daniel A. Ryan, Michael R. Krout, Raghu R. V. Malapaka, Jonathan Chow, Nicolas Manel, Maria Ciofani, Sangwon V. Kim, Adolfo Cuesta, Fabio R. Santori, Juan J. Lafaille, H. Eric Xu, David Y. Gin, Fraydoon Rastinejad and Dan R. Littman

Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand pp. 491-494

Laura A. Solt, Naresh Kumar, Philippe Nuhant, Yongjun Wang, Janelle L. Lauer, Jin Liu, Monica A. Istrate, Theodore M. Kamenecka, William R. Roush, Dušica Vidović, Stephan C. Schürer, Jihong Xu, Gail Wagoner, Paul D. Drew, Patrick R. Griffin and Thomas P. Burris

Differential microRNA regulation of HLA-C expression and its association with HIV control pp. 495-498

Smita Kulkarni, Ram Savan, Ying Qi, Xiaojiang Gao, Yuko Yuki, Sara E. Bass, Maureen P. Martin, Peter Hunt, Steven G. Deeks, Amalio Telenti, Florencia Pereyra, David Goldstein, Steven Wolinsky, Bruce Walker, Howard A. Young and Mary Carrington

A system for the continuous directed evolution of biomolecules pp. 499-503

Kevin M. Esvelt, Jacob C. Carlson and David R. Liu

Water and its influence on the lithosphere–asthenosphere boundary pp. 504-504

David H. Green, William O. Hibberson, István Kovács and Anja Rosenthal

Erratum: Extended megadroughts in the southwestern United States during Pleistocene interglacials pp. 504-504

Peter J. Fawcett, Josef P. Werne, R. Scott Anderson, Jeffrey M. Heikoop, Erik T. Brown, Melissa A. Berke, Susan J. Smith, Fraser Goff, Linda Donohoo-Hurley, Luz M. Cisneros-Dozal, Stefan Schouten, Jaap S. Sinninghe Damsté, Yongsong Huang, Jaime Toney, Julianna Fessenden, Giday WoldeGabriel, Viorel Atudorei, John W. Geissman and Craig D. Allen

Nuclear energy: Defying disaster pp. 505-505

Quirin Schiermeier

Turning point: Ian Chapman pp. 506-506

Virginia Gewin

A good time pp. 508-508

Shelly Li

2011, volume 472, articles 7343

Reform the PhD system or close it down pp. 261-261

Mark Taylor

US budget a taste of battles to come pp. 267-269

Eugenie Samuel Reich, Ivan Semeniuk, Jeff Tollefson and Meredith Wadman

Canadian research shift makes waves pp. 269-269

Hannah Hoag

A death in the lab pp. 270-271

Richard Van Noorden

Cancer theory faces doubts pp. 273-273

Heidi Ledford

Nuclear safety chief calls for reform pp. 274-274

Declan Butler

Education: The PhD factory pp. 276-279

David Cyranoski, Natasha Gilbert, Heidi Ledford, Anjali Nayar and Mohammed Yahia

Education: Rethinking PhDs pp. 280-282

Alison McCook

Seven ages of the PhD pp. 283-286

Raymond Gosling, Cheryll Tickle, Steve W. Running, Yao Tandong, Andras Dinnyes, A. A. Osowole and Erika Cule

The art of conservation pp. 287-289

Henry Nicholls

Conservation: Bringing back wildlife pp. 290-291

Nancy Lee Nash

Climate change: A dose of reality pp. 292-293

Tony McMichael

Art: Grime and punishment pp. 293-293

Daniel Cressey

Q&A: Animal distractions pp. 294-294

Isabella Rossellini

Doing the maths on the green economy pp. 295-295

Peter Victor and Tim Jackson

Academia resists clean-up in Romania pp. 295-295

Liviu Giosan

Science failed to self-regulate pp. 295-295

Frederik Trettin and Tobias Bunde

Fund biodiversity collections pp. 295-295

Flávio A. Bockmann

Jürg Tschopp (1951–2011) pp. 296-296

Vishva Dixit

Remarkable role for the placenta pp. 298-299

Ron McKay

Spot-on healing pp. 299-300

Nancy R. Sottos and Jeffrey S. Moore

Light sense pp. 300-301

Daniel Osorio

A route to quantum magnetism pp. 301-302

Ian B. Spielman

Macrophages limit chemotherapy pp. 303-304

Michele De Palma and Claire E. Lewis

Power surfing on waves pp. 304-305

Min Hyung Lee and Ali Javey

TRIM5 does double duty pp. 305-306

Christopher Aiken and Sebastian Joyce

Quantum simulation of antiferromagnetic spin chains in an optical lattice pp. 307-312

Jonathan Simon, Waseem S. Bakr, Ruichao Ma, M. Eric Tai, Philipp M. Preiss and Markus Greiner

Catecholamine receptor polymorphisms affect decision-making in C. elegans pp. 313-318

Andres Bendesky, Makoto Tsunozaki, Matthew V. Rockman, Leonid Kruglyak and Cornelia I. Bargmann

Caspase signalling controls microglia activation and neurotoxicity pp. 319-324

Miguel A. Burguillos, Tomas Deierborg, Edel Kavanagh, Annette Persson, Nabil Hajji, Albert Garcia-Quintanilla, Josefina Cano, Patrik Brundin, Elisabet Englund, Jose L. Venero and Bertrand Joseph

Crystal structure of inhibitor of κB kinase β pp. 325-330

Guozhou Xu, Yu-Chih Lo, Qiubai Li, Gennaro Napolitano, Xuefeng Wu, Xuliang Jiang, Michel Dreano, Michael Karin and Hao Wu

The auroral footprint of Enceladus on Saturn pp. 331-333

Wayne R. Pryor, Abigail M. Rymer, Donald G. Mitchell, Thomas W. Hill, David T. Young, Joachim Saur, Geraint H. Jones, Sven Jacobsen, Stan W. H. Cowley, Barry H. Mauk, Andrew J. Coates, Jacques Gustin, Denis Grodent, Jean-Claude Gérard, Laurent Lamy, Jonathan D. Nichols, Stamatios M. Krimigis, Larry W. Esposito, Michele K. Dougherty, Alain J. Jouchoux, A. Ian F. Stewart, William E. McClintock, Gregory M. Holsclaw, Joseph M. Ajello, Joshua E. Colwell, Amanda R. Hendrix, Frank J. Crary, John T. Clarke and Xiaoyan Zhou

Optically healable supramolecular polymers pp. 334-337

Mark Burnworth, Liming Tang, Justin R. Kumpfer, Andrew J. Duncan, Frederick L. Beyer, Gina L. Fiore, Stuart J. Rowan and Christoph Weder

Thermal history of Mars inferred from orbital geochemistry of volcanic provinces pp. 338-341

David Baratoux, Michael J. Toplis, Marc Monnereau and Olivier Gasnault

Metabolic trade-offs and the maintenance of the fittest and the flattest pp. 342-346

Robert E. Beardmore, Ivana Gudelj, David A. Lipson and Laurence D. Hurst

A transient placental source of serotonin for the fetal forebrain pp. 347-350

Alexandre Bonnin, Nick Goeden, Kevin Chen, Melissa L. Wilson, Jennifer King, Jean C. Shih, Randy D. Blakely, Evan S. Deneris and Pat Levitt

Neuronal activity is required for the development of specific cortical interneuron subtypes pp. 351-355

Natalia V. De Marco García, Theofanis Karayannis and Gord Fishell

Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration pp. 356-360

Aycan Sentürk, Sylvia Pfennig, Alexander Weiss, Katja Burk and Amparo Acker-Palmer

TRIM5 is an innate immune sensor for the retrovirus capsid lattice pp. 361-365

Thomas Pertel, Stéphane Hausmann, Damien Morger, Sara Züger, Jessica Guerra, Josefina Lascano, Christian Reinhard, Federico A. Santoni, Pradeep D. Uchil, Laurence Chatel, Aurélie Bisiaux, Matthew L. Albert, Caterina Strambio- De-Castillia, Walther Mothes, Massimo Pizzato, Markus G. Grütter and Jeremy Luban

A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK pp. 366-369

Damian F. Brennan, Arvin C. Dar, Nicholas T. Hertz, William C. H. Chao, Alma L. Burlingame, Kevan M. Shokat and David Barford

Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development pp. 370-374

Ikuhiro Okamoto, Catherine Patrat, Dominique Thépot, Nathalie Peynot, Patricia Fauque, Nathalie Daniel, Patricia Diabangouaya, Jean-Philippe Wolf, Jean-Paul Renard, Véronique Duranthon and Edith Heard

Genome-wide analysis reveals novel molecular features of mouse recombination hotspots pp. 375-378

Fatima Smagulova, Ivan V. Gregoretti, Kevin Brick, Pavel Khil, R. Daniel Camerini-Otero and Galina V. Petukhova

Start-ups: In search of venture capital pp. 379-380

Sarah Kellogg

What is a PhD really worth? pp. 381-381

Peter Fiske

Test of faith pp. 384-384

Brian P. Frank

2011, volume 472, articles 7342

Does blending of chlorophyll data bias temporal trend? pp. E4-E5

David L. Mackas

A measured look at ocean chlorophyll trends pp. E5-E6

Ryan R. Rykaczewski and John P. Dunne

Is there a decline in marine phytoplankton? pp. E6-E7

Abigail McQuatters-Gollop, Philip C. Reid, Martin Edwards, Peter H. Burkill, Claudia Castellani, Sonia Batten, Winfried Gieskes, Doug Beare, Robert R. Bidigare, Erica Head, Rod Johnson, Mati Kahru, J. Anthony Koslow and Angelica Pena

Boyce et al. reply pp. E8-E9

Daniel G. Boyce, Marlon R. Lewis and Boris Worm

Governments must pay for clean-energy innovation pp. 137-137

Marty Hoffert

Japan faces power struggle pp. 143-144

Jeff Tollefson

Radiation release will hit marine life pp. 145-146

Quirin Schiermeier

Fukushima set for epic clean-up pp. 146-147

Geoff Brumfiel

US legislation aims to simplify rules for inventors pp. 149-149

Eugenie Samuel Reich

Fossil data enter the web period pp. 150-150

Ewen Callaway

Oil spill: Deep wounds pp. 152-154

Mark Schrope

Neuroscience: Brain buzz pp. 156-159

Douglas Fox

Too much of a good thing pp. 159-161

Mark A. Sutton, Oene Oenema, Jan Willem Erisman, Adrian Leip, Hans van Grinsven and Wilfried Winiwarter

A frozen hell pp. 162-163

Jeffrey Short and Susan Murray

Medicine: Blood feud pp. 164-165

W. F. Bynum

Neuroethics: The origins of morality pp. 166-166

Adina L. Roskies

Biotechnology: DIY biology pp. 167-167

Bart Penders

Theatre: Newton's rainbow pp. 168-168

Philip Ball

FDA not NIH can speed new drugs pp. 169-169

Henry I. Miller

Libyan uprising may boost bluefin tuna pp. 169-169

David Grémillet and Amélie Lescroël

Predicting the threat of nuclear disasters pp. 169-169

A. M. Celâl Şengör

Regional drought has a global impact pp. 169-169

Troy Sternberg

Simon van der Meer (1925–2011) pp. 170-170

Carlo Rubbia

Spin drag in a perfect fluid pp. 172-173

John E. Thomas

Channelopathies have many faces pp. 173-174

Stephen G. Waxman

A jaw-dropping ear pp. 174-176

Anne Weil

How cells sense energy pp. 176-177

D. Grahame Hardie

Swimming in the Sahara pp. 177-178

Stephanie B. Crofts and Adam P. Summers

A closer look at polymer annealing pp. 178-179

Yi Fu and Joseph R. Lakowicz

Innate immunity cues virulence pp. 179-180

Michelle M. C. Buckner and B. Brett Finlay

Transitional mammalian middle ear from a new Cretaceous Jehol eutriconodont pp. 181-185

Jin Meng, Yuanqing Wang and Chuankui Li

Loss-of-function mutations in sodium channel Nav1.7 cause anosmia pp. 186-190

Jan Weiss, Martina Pyrski, Eric Jacobi, Bernd Bufe, Vivienne Willnecker, Bernhard Schick, Philippe Zizzari, Samuel J. Gossage, Charles A. Greer, Trese Leinders-Zufall, C. Geoffrey Woods, John N. Wood and Frank Zufall

Cortical representations of olfactory input by trans-synaptic tracing pp. 191-196

Kazunari Miyamichi, Fernando Amat, Farshid Moussavi, Chen Wang, Ian Wickersham, Nicholas R. Wall, Hiroki Taniguchi, Bosiljka Tasic, Z. Josh Huang, Zhigang He, Edward M. Callaway, Mark A. Horowitz and Liqun Luo

Magneto-thermal convection in solar prominences pp. 197-200

Thomas Berger, Paola Testa, Andrew Hillier, Paul Boerner, Boon Chye Low, Kazunari Shibata, Carolus Schrijver, Ted Tarbell and Alan Title

Universal spin transport in a strongly interacting Fermi gas pp. 201-204

Ariel Sommer, Mark Ku, Giacomo Roati and Martin W. Zwierlein

Transient ferromagnetic-like state mediating ultrafast reversal of antiferromagnetically coupled spins pp. 205-208

I. Radu, K. Vahaplar, C. Stamm, T. Kachel, N. Pontius, H. A. Dürr, T. A. Ostler, J. Barker, R. F. L. Evans, R. W. Chantrell, A. Tsukamoto, A. Itoh, A. Kirilyuk, Th. Rasing and A. V. Kimel

Redox freezing and melting in the Earth’s deep mantle resulting from carbon–iron redox coupling pp. 209-212

Arno Rohrbach and Max W. Schmidt

Distinct representations of olfactory information in different cortical centres pp. 213-216

Dara L. Sosulski, Maria Lissitsyna Bloom, Tyler Cutforth, Richard Axel and Sandeep Robert Datta

Sensory maps in the olfactory cortex defined by long-range viral tracing of single neurons pp. 217-220

Sulagna Ghosh, Stephen D. Larson, Hooman Hefzi, Zachary Marnoy, Tyler Cutforth, Kartheek Dokka and Kristin K. Baldwin

Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome pp. 221-225

Guang-Hui Liu, Basam Z. Barkho, Sergio Ruiz, Dinh Diep, Jing Qu, Sheng-Lian Yang, Athanasia D. Panopoulos, Keiichiro Suzuki, Leo Kurian, Christopher Walsh, James Thompson, Stephanie Boue, Ho Lim Fung, Ignacio Sancho-Martinez, Kun Zhang, John Yates and Juan Carlos Izpisua Belmonte

Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan pp. 226-229

Silvestre Alavez, Maithili C. Vantipalli, David J. S. Zucker, Ida M. Klang and Gordon J. Lithgow

Structure of mammalian AMPK and its regulation by ADP pp. 230-233

Bing Xiao, Matthew J. Sanders, Elizabeth Underwood, Richard Heath, Faith V. Mayer, David Carmena, Chun Jing, Philip A. Walker, John F. Eccleston, Lesley F. Haire, Peter Saiu, Steven A. Howell, Rein Aasland, Stephen R. Martin, David Carling and Steven J. Gamblin

Structural basis for recognition of centromere histone variant CenH3 by the chaperone Scm3 pp. 234-237

Zheng Zhou, Hanqiao Feng, Bing-Rui Zhou, Rodolfo Ghirlando, Kaifeng Hu, Adam Zwolak, Lisa M. Miller Jenkins, Hua Xiao, Nico Tjandra, Carl Wu and Yawen Bai

A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export pp. 238-242

Ben Montpetit, Nathan D. Thomsen, Kara J. Helmke, Markus A. Seeliger, James M. Berger and Karsten Weis

Structure and mechanism of the uracil transporter UraA pp. 243-246

Feiran Lu, Shuo Li, Yang Jiang, Jing Jiang, He Fan, Guifeng Lu, Dong Deng, Shangyu Dang, Xu Zhang, Jiawei Wang and Nieng Yan

Erratum: Mediator and cohesin connect gene expression and chromatin architecture pp. 247-247

Michael H. Kagey, Jamie J. Newman, Steve Bilodeau, Ye Zhan, David A. Orlando, Nynke L. van Berkum, Christopher C. Ebmeier, Jesse Goossens, Peter B. Rahl, Stuart S. Levine, Dylan J. Taatjes, Job Dekker and Richard A. Young

Erratum: Holocene Southern Ocean surface temperature variability west of the Antarctic Peninsula pp. 247-247

A. E. Shevenell, A. E. Ingalls, E. W. Domack and C. Kelly

Erratum: H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes pp. 247-247

Beth A. Helmink, Anthony T. Tubbs, Yair Dorsett, Jeffrey J. Bednarski, Laura M.Walker, Zhihui Feng, Girdhar G. Sharma, Peter J. McKinnon, Junran Zhang, Craig H. Bassing and Barry P. Sleckman

Consulting: Juggling act pp. 249-251

Amanda Leigh Mascarelli

Turning point: Giovanna Tinetti pp. 251-251

Virginia Gewin

Steve Sepp, Tasty! Tasty! pp. 254-254

Matthew Sanborn Smith

2011, volume 472, articles 7341

Isotope fractionation in silicate melts by thermal diffusion pp. E1-E1

Frank M. Richter

Huang et al. reply pp. E2-E3

F. Huang, P. Chakraborty, C. C. Lundstrom, C. Holmden, J. J. G. Glessner, S. W. Kieffer and C. E. Lesher

A long shadow over Fukushima pp. 7-7

Jim Smith

Fukushima health risks scrutinized pp. 13-14

Declan Butler

Japan's long road ahead pp. 14-14

Geoff Brumfiel

US radiation study sparks debate pp. 15-15

Gwyneth Dickey Zakaib

NASA human space-flight programme lost in transition pp. 16-17

Adam Mann

Rare-disease project has global ambitions pp. 17-17

Alison Abbott

Bulgarian funding agency accused of poor practice pp. 19-19

Alison Abbott

Patent dispute threatens US Alzheimer's research pp. 20-20

Erika Check Hayden

Materials science: The pull of stronger magnets pp. 22-23

Nicola Jones

Developing world: Educating India pp. 24-26

Anjali Nayar

The search for clean cash pp. 30-31

David Kaiser

Fix the antibiotics pipeline pp. 32-32

Matthew A. Cooper and David Shlaes

Psychology: The art of remembering pp. 33-34

Larry R. Squire

Globalization: Behind India's technological boom pp. 34-35

Andrew Robinson

Astronomy: Finding other worlds pp. 36-36

Chris Tinney

Communication: Show and tell pp. 37-37

David Carmel

China's green policy has some way to go pp. 38-38

Tong Wu

An insight into Maxwell's mind? pp. 38-38

David J. Tyler

Financial model failed in real world pp. 38-38

Robin O. Motz

Shuttle programme lifetime cost pp. 38-38

Roger Pielke and Radford Byerly

The diet–microbe morbid union pp. 40-41

Kimberly Rak and Daniel J. Rader

Industry-compatible graphene transistors pp. 41-42

Frank Schwierz

DIY eye pp. 42-43

Robin R. Ali and Jane C. Sowden

When glacial giants roll over pp. 43-44

Anders Levermann

Diversity favours productivity pp. 45-46

Andy Hector

Bone returns the favour pp. 46-47

Sonya M. Schuh-Huerta and Renee A. Reijo Pera

A smoother end to the dark ages pp. 47-48

Zoltán Haiman

A new mechanical model for Tibet pp. 48-49

Jeffrey T. Freymueller

Self-organizing optic-cup morphogenesis in three-dimensional culture pp. 51-56

Mototsugu Eiraku, Nozomu Takata, Hiroki Ishibashi, Masako Kawada, Eriko Sakakura, Satoru Okuda, Kiyotoshi Sekiguchi, Taiji Adachi and Yoshiki Sasai

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease pp. 57-63

Zeneng Wang, Elizabeth Klipfell, Brian J. Bennett, Robert Koeth, Bruce S. Levison, Brandon DuGar, Ariel E. Feldstein, Earl B. Britt, Xiaoming Fu, Yoon-Mi Chung, Yuping Wu, Phil Schauer, Jonathan D. Smith, Hooman Allayee, W. H. Wilson Tang, Joseph A. DiDonato, Aldons J. Lusis and Stanley L. Hazen

Streptococcal M1 protein constructs a pathological host fibrinogen network pp. 64-68

Pauline Macheboeuf, Cosmo Buffalo, Chi-yu Fu, Annelies S. Zinkernagel, Jason N. Cole, John E. Johnson, Victor Nizet and Partho Ghosh

Electromagnetically induced transparency and slow light with optomechanics pp. 69-73

A. H. Safavi-Naeini, T. P. Mayer Alegre, J. Chan, M. Eichenfield, M. Winger, Q. Lin, J. T. Hill, D. E. Chang and O. Painter

High-frequency, scaled graphene transistors on diamond-like carbon pp. 74-78

Yanqing Wu, Yu-ming Lin, Ageeth A. Bol, Keith A. Jenkins, Fengnian Xia, Damon B. Farmer, Yu Zhu and Phaedon Avouris

Evidence for mechanical coupling and strong Indian lower crust beneath southern Tibet pp. 79-81

Alex Copley, Jean-Philippe Avouac and Brian P. Wernicke

Low strength of deep San Andreas fault gouge from SAFOD core pp. 82-85

David A. Lockner, Carolyn Morrow, Diane Moore and Stephen Hickman

Biodiversity improves water quality through niche partitioning pp. 86-89

Bradley J. Cardinale

Tumour evolution inferred by single-cell sequencing pp. 90-94

Nicholas Navin, Jude Kendall, Jennifer Troge, Peter Andrews, Linda Rodgers, Jeanne McIndoo, Kerry Cook, Asya Stepansky, Dan Levy, Diane Esposito, Lakshmi Muthuswamy, Alex Krasnitz, W. Richard McCombie, James Hicks and Michael Wigler

Molecular regulation of sexual preference revealed by genetic studies of 5-HT in the brains of male mice pp. 95-99

Yan Liu, Yun’ai Jiang, Yunxia Si, Ji-Young Kim, Zhou-Feng Chen and Yi Rao

Local, persistent activation of Rho GTPases during plasticity of single dendritic spines pp. 100-104

Hideji Murakoshi, Hong Wang and Ryohei Yasuda

Dampening of death pathways by schnurri-2 is essential for T-cell development pp. 105-109

Tracy L. Staton, Vanja Lazarevic, Dallas C. Jones, Amanda J. Lanser, Tsuyoshi Takagi, Shunsuke Ishii and Laurie H. Glimcher

Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder pp. 110-114

Kunyoo Shin, John Lee, Nini Guo, James Kim, Agnes Lim, Lishu Qu, Indira U. Mysorekar and Philip A. Beachy

An siRNA pathway prevents transgenerational retrotransposition in plants subjected to stress pp. 115-119

Hidetaka Ito, Hervé Gaubert, Etienne Bucher, Marie Mirouze, Isabelle Vaillant and Jerzy Paszkowski

A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression pp. 120-124

Kevin C. Wang, Yul W. Yang, Bo Liu, Amartya Sanyal, Ryan Corces-Zimmerman, Yong Chen, Bryan R. Lajoie, Angeline Protacio, Ryan A. Flynn, Rajnish A. Gupta, Joanna Wysocka, Ming Lei, Job Dekker, Jill A. Helms and Howard Y. Chang

California: Safe harbour pp. 125-126

Karen Kaplan

Waiting for the motivation fairy pp. 127-127

Hugh Kearns and Maria Gardiner

Shift pp. 130-130

Liz Williams