Post-replicative repair involves separase-dependent removal of the kleisin subunit of cohesin

Alexandra McAleenan, Andres Clemente-Blanco, Violeta Cordon-Preciado, Nicholas Sen, Miguel Esteras, Adam Jarmuz and Luis Aragón ()
Additional contact information
Alexandra McAleenan: Cell Cycle Group, MRC Clinical Sciences Centre, Imperial College, Du Cane Road, London W12 0NN, UK
Andres Clemente-Blanco: Cell Cycle Group, MRC Clinical Sciences Centre, Imperial College, Du Cane Road, London W12 0NN, UK
Violeta Cordon-Preciado: Cell Cycle Group, MRC Clinical Sciences Centre, Imperial College, Du Cane Road, London W12 0NN, UK
Nicholas Sen: Cell Cycle Group, MRC Clinical Sciences Centre, Imperial College, Du Cane Road, London W12 0NN, UK
Miguel Esteras: Cell Cycle Group, MRC Clinical Sciences Centre, Imperial College, Du Cane Road, London W12 0NN, UK
Adam Jarmuz: Cell Cycle Group, MRC Clinical Sciences Centre, Imperial College, Du Cane Road, London W12 0NN, UK
Luis Aragón: Cell Cycle Group, MRC Clinical Sciences Centre, Imperial College, Du Cane Road, London W12 0NN, UK

Nature, 2013, vol. 493, issue 7431, 250-254

Abstract: Cohesin, which tethers sister chromatids together, is found to be cleaved by separase after DNA damage, resulting in cohesin dissociation and allowing for post-replicative repair of DNA double-strand breaks.

Date: 2013
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/nature11630 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:493:y:2013:i:7431:d:10.1038_nature11630

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature11630

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().