Control of somatic tissue differentiation by the long non-coding RNA TINCR

Markus Kretz, Zurab Siprashvili, Ci Chu, Dan E. Webster, Ashley Zehnder, Kun Qu, Carolyn S. Lee, Ross J. Flockhart, Abigail F. Groff, Jennifer Chow, Danielle Johnston, Grace E. Kim, Robert C. Spitale, Ryan A. Flynn, Grace X. Y. Zheng, Subhadra Aiyer, Arjun Raj, John L. Rinn, Howard Y. Chang () and Paul A. Khavari ()
Additional contact information
Markus Kretz: The Program in Epithelial Biology, Stanford University School of Medicine
Zurab Siprashvili: The Program in Epithelial Biology, Stanford University School of Medicine
Ci Chu: The Program in Epithelial Biology, Stanford University School of Medicine
Dan E. Webster: The Program in Epithelial Biology, Stanford University School of Medicine
Ashley Zehnder: The Program in Epithelial Biology, Stanford University School of Medicine
Kun Qu: The Program in Epithelial Biology, Stanford University School of Medicine
Carolyn S. Lee: The Program in Epithelial Biology, Stanford University School of Medicine
Ross J. Flockhart: The Program in Epithelial Biology, Stanford University School of Medicine
Abigail F. Groff: The Program in Epithelial Biology, Stanford University School of Medicine
Jennifer Chow: The Program in Epithelial Biology, Stanford University School of Medicine
Danielle Johnston: The Program in Epithelial Biology, Stanford University School of Medicine
Grace E. Kim: The Program in Epithelial Biology, Stanford University School of Medicine
Robert C. Spitale: The Program in Epithelial Biology, Stanford University School of Medicine
Ryan A. Flynn: The Program in Epithelial Biology, Stanford University School of Medicine
Grace X. Y. Zheng: The Program in Epithelial Biology, Stanford University School of Medicine
Subhadra Aiyer: University of Pennsylvania
Arjun Raj: University of Pennsylvania
John L. Rinn: Harvard University
Howard Y. Chang: The Program in Epithelial Biology, Stanford University School of Medicine
Paul A. Khavari: The Program in Epithelial Biology, Stanford University School of Medicine

Nature, 2013, vol. 493, issue 7431, 231-235

Abstract: The human long non-coding RNA TINCR binds to STAU1 and controls epidermal differentiation by stabilizing key differentiation mRNAs, by means of a TINCR-binding motif found enriched in epidermal differentiation genes.

Date: 2013
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DOI: 10.1038/nature11661

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