Genetic identification of C fibres that detect massage-like stroking of hairy skin in vivo

Sophia Vrontou, Allan M. Wong, Kristofer K. Rau, H. Richard Koerber and David J. Anderson ()
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Sophia Vrontou: California Institute of Technology
Allan M. Wong: California Institute of Technology
Kristofer K. Rau: University of Louisville
H. Richard Koerber: University of Pittsburgh
David J. Anderson: California Institute of Technology

Nature, 2013, vol. 493, issue 7434, 669-673

Abstract: Calcium imaging in live mice shows that a rare population of unmyelinated sensory neurons—expressing the G-protein-coupled receptor MRGPRB4—responds specifically to massage-like stroking of hairy skin, with positive reinforcing behavioural effects.

Date: 2013
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DOI: 10.1038/nature11810

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