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2025, volume 644, articles 8077

Is collapsing fertility really the end of the world? pp. 594-596

Lynne Peeples

Why amphibious, wet environments hold the key to climate adaptation pp. 601-602

Ananya

Swift bricks, ancient tattoos and more: Books in brief pp. 602-602

Andrew Robinson

Margaret Boden obituary: cognitive scientist who explored how machines might emulate human imagination pp. 603-603

Joanna Bryson

Protect Antarctica — or risk accelerating planetary meltdown pp. 605-607

Ida Kubiszewski, Robert Costanza, Elizabeth A. Fulton, Matt A. King, Elizabeth Leane and Natalie Stoeckl

Battery prices are falling, so why are electric cars still so expensive? pp. 608-610

Lucas Woodley, Chung Yi See and Ashley Nunes

African countries must rethink health-care financing pp. 611-611

Jean Kaseya, Nebiyu Dereje, Raji Tajudeen and Ngashi Ngongo

China’s hydropower megaproject breaks ground pp. 611-611

Rui Feng, Kejia Fan, Yongjun Zhao and Zhuangzhou Qi

Study protected waters newly opened up to fishing pp. 611-611

Angelo Villagomez, Kirsten Grorud-Colvert, Jenna Sullivan-Stack and Steven Mana’oakamai Johnson

Include Indigenous Knowledge systems in climate reports pp. 611-611

Bradley Moggridge, Vinnitta Mosby, Sandra Creamer and Nina Lansbury

3D printing offers a way to study mimicry by insects pp. 613-614

Thomas N. Sherratt and Karl Loeffler-Henry

Weight loss alters adipose tissue beyond just reducing fat pp. 616-617

Evan D. Rosen and Margo P. Emont

The curious case of how bird wrists evolved pp. 619-620

Xing Xu

Beyond AlphaFold: how AI is decoding the grammar of the genome pp. 829-832

Jeffrey M. Perkel

Raw ingredients: turning algal protein into mock meat pp. 834-834

Christine Ro

2025, volume 644, articles 8076

Accuracy of rubber-related deforestation maps pp. E13-E19

Nguyen Tien Hoang, Peter Potapov, Pontus Olofsson and Keiichiro Kanemoto

Rubber planting and deforestation pp. E20-E22

Douglas Sheil, Adrià Descals, Erik Meijaard and David Gaveau

Y. Wang et al. reply pp. E23-E26

Yunxia Wang, Peter M. Hollingsworth, Deli Zhai, Christopher D. West, Jonathan Green, Sam Harrison, Huafang Chen, Kaspar Hurni, Yufang Su, Eleanor Warren-Thomas, Jianchu Xu and Antje Ahrends

Spatial correlation in economic analysis of climate change pp. E27-E30

Christof Schötz

Author Correction: Spatial immune scoring system predicts hepatocellular carcinoma recurrence pp. E31-E31

Gengjie Jia, Peiqi He, Tianli Dai, Denise Goh, Jiabei Wang, Mengyuan Sun, Felicia Wee, Fuling Li, Jeffrey Chun Tatt Lim, Shuxia Hao, Yao Liu, Tony Kiat Hon Lim, Nye-Thane Ngo, Qingping Tao, Wei Wang, Ahitsham Umar, Björn Nashan, Yongchang Zhang, Chen Ding, Joe Yeong, Lianxin Liu and Cheng Sun

Author Correction: Early versus deferred use of CDK4/6 inhibitors in advanced breast cancer pp. E32-E32

Gabe S. Sonke, Annemiek Ommen-Nijhof, Noor Wortelboer, Vincent Noort, Astrid C. P. Swinkels, Hedwig M. Blommestein, Cristina Guerrero Paez, Linda Mol, Aart Beeker, Karin Beelen, Lisanne C. Hamming, Joan B. Heijns, Aafke H. Honkoop, Paul C. Jong, Quirine C. Rossum-Schornagel, Christa Schaik- van de Mheen, Jolien Tol, Cathrien S. Tromp- van Driel, Suzan Vrijaldenhoven, A. Elise Leeuwen-Stok, Inge R. Konings and Agnes Jager

Author Correction: Immune evasion through mitochondrial transfer in the tumour microenvironment pp. E33-E33

Hideki Ikeda, Katsushige Kawase, Tatsuya Nishi, Tomofumi Watanabe, Keizo Takenaga, Takashi Inozume, Takamasa Ishino, Sho Aki, Jason Lin, Shusuke Kawashima, Joji Nagasaki, Youki Ueda, Shinichiro Suzuki, Hideki Makinoshima, Makiko Itami, Yuki Nakamura, Yasutoshi Tatsumi, Yusuke Suenaga, Takao Morinaga, Akiko Honobe-Tabuchi, Takehiro Ohnuma, Tatsuyoshi Kawamura, Yoshiyasu Umeda, Yasuhiro Nakamura, Yukiko Kiniwa, Eiki Ichihara, Hidetoshi Hayashi, Jun-ichiro Ikeda, Toyoyuki Hanazawa, Shinichi Toyooka, Hiroyuki Mano, Takuji Suzuki, Tsuyoshi Osawa, Masahito Kawazu and Yosuke Togashi

Author Correction: Human HDAC6 senses valine abundancy to regulate DNA damage pp. E34-E34

Jiali Jin, Tong Meng, Yuanyuan Yu, Shuheng Wu, Chen-Chen Jiao, Sihui Song, Ya-Xu Li, Yu Zhang, Yuan-Yuan Zhao, Xinran Li, Zixin Wang, Yu-Fan Liu, Runzhi Huang, Jieling Qin, Yihua Chen, Hao Cao, Xiao Tan, Xin Ge, Cong Jiang, Jianhuang Xue, Jian Yuan, Dianqing Wu, Wei Wu, Ci-Zhong Jiang and Ping Wang

‘A whole body of health-equity research is being disappeared’ — why I resigned from the NIH pp. 307-307

Vani Pariyadath

Just how bad will climate change get? The only way to know is to fund basic research pp. 308-308

Tim Palmer

mRNA vaccines for HIV trigger strong immune response in people pp. 311-312

Smriti Mallapaty

Sexual harassment is rife at US Antarctic research bases, fresh survey finds pp. 312-313

Alexandra Witze

Google AI model mines trillions of images to create maps of Earth ‘at any place and time’ pp. 313-314

Jeff Tollefson

‘Sleeping’ cancer cells in the lungs can be roused by COVID and flu pp. 314-315

Max Kozlov

Eating ultra-processed foods could make it harder to lose weight pp. 315-316

Katie Kavanagh

UK Royal Society adopts ‘subscribe to open’ publishing model pp. 316-317

Miryam Naddaf

India to penalize universities with too many retractions pp. 317-318

Smriti Mallapaty

Is gravity quantum? Experiments could finally probe one of physics’ biggest questions pp. 320-323

Davide Castelvecchi

Trump’s chief science adviser faces a storm of criticism: what's next? pp. 324-326

Jeff Tollefson

‘A biographer’s dream’: this physicist investigated UFOs and flew over Hiroshima pp. 328-329

Robert P. Crease

George E. Smith obituary: co-inventor of the charge coupled device, which ushered in an era of digital images pp. 330-330

Simon Tulloch

Decolonize scientific institutions, don’t just diversify them pp. 331-334

Tara G. McAllister, Leilani A. Walker, Niiyokamigaabaw Deondre Smiles, Lydia Jennings, Bradley Moggridge, Sereana Naepi, Brittany Kamai and Kat Milligan-McClellan

Nuclear-weapons risks are back — and we need to act like it pp. 335-337

Ankit Panda

Organs on chips could make biomedical research more equitable pp. 338-338

Andrea C. del Valle

Study how screen time affects circadian rhythms pp. 338-338

Fouzia Kiran, Yaping Jin, Yalin Yuan and Huatao Chen

Use AI in the classroom to bring problems to life pp. 338-338

Zerong Xie and Chenwei Zhang

Europe must safeguard climate data following NASA cuts pp. 338-338

Bernard Pinty and Jean-Noël Thépaut

Levitating platform could ride sunlight into the ‘ignorosphere’ pp. 339-340

Igor Bargatin

Plagues of locusts could be avoided by using compounds that suppress swarming pp. 340-341

Markus Knaden

Impact of catastrophic flood might have been exacerbated by river-management programme pp. 342-343

Alvise Finotello

Genetic mutation predicts survival after immunotherapy for ovarian cancer pp. 343-345

Sarah Adams

Injured plants use gaseous cues to initiate repair of their outer layers pp. 345-346

Cui-Cui Yin and Jin-Song Zhang

Bending the curve of land degradation to achieve global environmental goals pp. 347-355

Fernando T. Maestre, Emilio Guirado, Dolors Armenteras, Hylke E. Beck, Mashael Saud AlShalan, Noura Turki Al-Saud, Ralph Chami, Bojie Fu, Helene Gichenje, Elisabeth Huber-Sannwald, Chinwe Ifejika Speranza, Jaime Martínez-Valderrama, Matthew F. McCabe, Barron J. Orr, Ting Tang, Graciela Metternicht, Michael Miess, James F. Reynolds, Lindsay C. Stringer, Yoshihide Wada and Carlos M. Duarte

One-third of Sun-like stars are born with misaligned planet-forming disks pp. 356-361

Lauren I. Biddle, Brendan P. Bowler, Marvin Morgan, Quang H. Tran and Ya-Lin Wu

Photophoretic flight of perforated structures in near-space conditions pp. 362-369

Benjamin C. Schafer, Jong-hyoung Kim, Felix Sharipov, Gyeong-Seok Hwang, Joost J. Vlassak and David W. Keith

Synthesis of bulk hexagonal diamond pp. 370-375

Liuxiang Yang, Kah Chun Lau, Zhidan Zeng, Dongzhou Zhang, Hu Tang, Bingmin Yan, Guoliang Niu, Huiyang Gou, Yanping Yang, Wenge Yang, Duan Luo and Ho-kwang Mao

Direct identification of Ac and No molecules with an atom-at-a-time technique pp. 376-380

Jennifer L. Pore, Jacklyn M. Gates, David A. Dixon, Fatima H. Garcia, John K. Gibson, John A. Gooding, Mallory McCarthy, Rodney Orford, Ziad Shafi, David K. Shuh and Sarah Sprouse

Repurposing haemoproteins for asymmetric metal-catalysed H atom transfer pp. 381-390

Xiang Zhang, Dongping Chen, María Álvarez and Thomas R. Ward

Extreme river flood exposes latent erosion risk pp. 391-397

H. J. Barneveld, R. M. Frings, E. Mosselman, J. G. Venditti, M. G. Kleinhans, A. Blom, R. M. J. Schielen, W. H. J. Toonen, D. Meijer, A. J. Paarlberg, R. P. Denderen, J. S. Jong, J. G. W. Beemster, L. A. Melsen and A. J. F. Hoitink

Large riverbed sediment flux sustained for a decade after an earthquake pp. 398-403

Gen K. Li, A. Joshua West, Zhangdong Jin, Hongrui Qiu, Fei Zhang, Jin Wang, Douglas E. Hammond, Alexander L. Densmore, Robert G. Hilton, Sijia Dong, Abra Atwood, Woodward W. Fischer and Michael P. Lamb

Calving-driven fjord dynamics resolved by seafloor fibre sensing pp. 404-412

Dominik Gräff, Bradley Paul Lipovsky, Andreas Vieli, Armin Dachauer, Rebecca Jackson, Daniel Farinotti, Julia Schmale, Jean-Paul Ampuero, Eric Berg, Anke Dannowski, Andrea Kneib-Walter, Manuela Köpfli, Heidrun Kopp, Enrico Loo, Daniel Mata Flores, Diego Mercerat, Raphael Moser, Anthony Sladen, Fabian Walter, Diego Wasser, Ethan Welty, Selina Wetter and Ethan F. Williams

A global humidity index with lateral hydrologic flows pp. 413-419

Gonzalo Miguez-Macho and Ying Fan

Decoding 4-vinylanisole biosynthesis and pivotal enzymes in locusts pp. 420-429

Xiaojiao Guo, Lei Gao, Shiwei Li, Jing Gao, Yuanyuan Wang, Jing Lv, Jiayi Wei, Jing Yang, Han Ke, Qi Ding, Jun Yang, Fusheng Guo, Haowen Zhang, Xiaoguang Lei and Le Kang

Complex genetic variation in nearly complete human genomes pp. 430-441

Glennis A. Logsdon, Peter Ebert, Peter A. Audano, Mark Loftus, David Porubsky, Jana Ebler, Feyza Yilmaz, Pille Hallast, Timofey Prodanov, DongAhn Yoo, Carolyn A. Paisie, William T. Harvey, Xuefang Zhao, Gianni V. Martino, Mir Henglin, Katherine M. Munson, Keon Rabbani, Chen-Shan Chin, Bida Gu, Hufsah Ashraf, Stephan Scholz, Olanrewaju Austine-Orimoloye, Parithi Balachandran, Marc Jan Bonder, Haoyu Cheng, Zechen Chong, Jonathan Crabtree, Mark Gerstein, Lisbeth A. Guethlein, Patrick Hasenfeld, Glenn Hickey, Kendra Hoekzema, Sarah E. Hunt, Matthew Jensen, Yunzhe Jiang, Sergey Koren, Youngjun Kwon, Chong Li, Heng Li, Jiaqi Li, Paul J. Norman, Keisuke K. Oshima, Benedict Paten, Adam M. Phillippy, Nicholas R. Pollock, Tobias Rausch, Mikko Rautiainen, Yuwei Song, Arda Söylev, Arvis Sulovari, Likhitha Surapaneni, Vasiliki Tsapalou, Weichen Zhou, Ying Zhou, Qihui Zhu, Michael C. Zody, Ryan E. Mills, Scott E. Devine, Xinghua Shi, Michael E. Talkowski, Mark J. P. Chaisson, Alexander T. Dilthey, Miriam K. Konkel, Jan O. Korbel, Charles Lee, Christine R. Beck, Evan E. Eichler and Tobias Marschall

Structural variation in 1,019 diverse humans based on long-read sequencing pp. 442-452

Siegfried Schloissnig, Samarendra Pani, Jana Ebler, Carsten Hain, Vasiliki Tsapalou, Arda Söylev, Patrick Hüther, Hufsah Ashraf, Timofey Prodanov, Mila Asparuhova, Hugo Magalhães, Wolfram Höps, Jesus Emiliano Sotelo-Fonseca, Tomas Fitzgerald, Walter Santana-Garcia, Ricardo Moreira-Pinhal, Sarah Hunt, Francy J. Pérez-Llanos, Tassilo Erik Wollenweber, Sugirthan Sivalingam, Dagmar Wieczorek, Mario Cáceres, Christian Gilissen, Ewan Birney, Zhihao Ding, Jan Nygaard Jensen, Nikhil Podduturi, Jan Stutzki, Bernardo Rodriguez-Martin, Tobias Rausch, Tobias Marschall and Jan O. Korbel

Molecular gradients shape synaptic specificity of a visuomotor transformation pp. 453-462

Mark Dombrovski, Yixin Zang, Giovanni Frighetto, Andrea Vaccari, HyoJong Jang, Parmis S. Mirshahidi, Fangming Xie, Piero Sanfilippo, Bryce W. Hina, Aadil Rehan, Roni H. Hussein, Pegah S. Mirshahidi, Catherine Lee, Aileen Morris, Mark A. Frye, Catherine R. Reyn, Yerbol Z. Kurmangaliyev, Gwyneth M. Card and S. Lawrence Zipursky

Preoptic EP3R neurons constitute a two-way switch for fever and torpor pp. 463-472

Natalia L. S. Machado, Nicole Lynch, Luis H. A. Costa, David Melville, Hakan Kucukdereli, Satvinder Kaur, Alexander S. Banks, Francesca Raffin, Oscar D. Ramirez-Plascencia, Sydney Aten, Janayna D. Lima, Sathyajit S. Bandaru, Richard D. Palmiter and Clifford B. Saper

Mouse liver assembloids model periportal architecture and biliary fibrosis pp. 473-482

Anna M. Dowbaj, Aleksandra Sljukic, Armin Niksic, Cedric Landerer, Julien Delpierre, Haochen Yang, Aparajita Lahree, Ariane C. Kühn, David Beers, Helen M. Byrne, Sarah Seifert, Heather A. Harrington, Marino Zerial and Meritxell Huch

Plants monitor the integrity of their barrier by sensing gas diffusion pp. 483-489

Hiroyuki Iida, Isidro Abreu, Jennifer López Ortiz, Lucas León Peralta Ogorek, Vinay Shukla, Meeri Mäkelä, Munan Lyu, Alexey Shapiguzov, Francesco Licausi and Ari Pekka Mähönen

Electron flow in hydrogenotrophic methanogens under nickel limitation pp. 490-496

Shunsuke Nomura, Pablo San Segundo-Acosta, Evgenii Protasov, Masanori Kaneko, Jörg Kahnt, Bonnie J. Murphy and Seigo Shima

Non-antibiotics disrupt colonization resistance against enteropathogens pp. 497-505

Anne Grießhammer, Jacobo de la Cuesta-Zuluaga, Patrick Müller, Cordula Gekeler, Jan Homolak, Hsuan Chang, Katharina Schmitt, Chiara Planker, Verena Schmidtchen, Suchira Gallage, Erwin Bohn, Taylor H. Nguyen, Jenny Hetzer, Mathias Heikenwälder, Kerwyn Casey Huang, Taiyeb Zahir and Lisa Maier

Identification of medication–microbiome interactions that affect gut infection pp. 506-515

Aman Kumar, Ruizheng Sun, Bettina Habib, Tong Deng, Natasha A. Bencivenga-Barry, Noah W. Palm, Ivaylo I. Ivanov, Robyn Tamblyn and Andrew L. Goodman

Pathology-oriented multiplexing enables integrative disease mapping pp. 516-526

Malte Kuehl, Yusuke Okabayashi, Milagros N. Wong, Lukas Gernhold, Gabriele Gut, Nico Kaiser, Maria Schwerk, Stefanie K. Gräfe, Frank Y. Ma, Jovan Tanevski, Philipp S. L. Schäfer, Sam Mezher, Jacobo Sarabia del Castillo, Thiago Goldbeck-Strieder, Olga Zolotareva, Michael Hartung, Fernando M. Delgado Chaves, Lukas Klinkert, Ann-Christin Gnirck, Marc Spehr, David Fleck, Mehdi Joodaki, Victor Parra, Mina Shaigan, Martin Diebold, Marco Prinz, Jennifer Kranz, Johan M. Kux, Fabian Braun, Oliver Kretz, Hui Wu, Florian Grahammer, Sven Heins, Marina Zimmermann, Fabian Haas, Dominik Kylies, Nicola Wanner, Jan Czogalla, Bernhard Dumoulin, Nikolay Zolotarev, Maja Lindenmeyer, Pall Karlson, Jens R. Nyengaard, Marcial Sebode, Sören Weidemann, Thorsten Wiech, Hermann-Josef Groene, Nicola M. Tomas, Catherine Meyer-Schwesinger, Christoph Kuppe, Rafael Kramann, Alexandre Karras, Patrick Bruneval, Pierre-Louis Tharaux, Diego Pastene, Benito Yard, Jennifer A. Schaub, Phillip J. McCown, Laura Pyle, Ye Ji Choi, Takashi Yokoo, Jan Baumbach, Pablo J. Sáez, Ivan Costa, Jan-Eric Turner, Jeffrey B. Hodgin, Julio Saez-Rodriguez, Tobias B. Huber, Petter Bjornstad, Matthias Kretzler, Olivia Lenoir, David J. Nikolic-Paterson, Lucas Pelkmans, Stefan Bonn and Victor G. Puelles

Humoral determinants of checkpoint immunotherapy pp. 527-536

Yile Dai, Lilach Aizenbud, Kai Qin, Matthew Austin, Jillian R. Jaycox, Joseph Cunningham, Eric Y. Wang, Lin Zhang, Suzanne Fischer, Sean M. Carroll, Helen Aggelen, Yuval Kluger, Kevan C. Herold, Leon Furchtgott, Harriet M. Kluger and Aaron M. Ring

PPP2R1A mutations portend improved survival after cancer immunotherapy pp. 537-546

Yibo Dai, Anne Knisely, Mitsutake Yano, Minghao Dang, Emily M. Hinchcliff, Sanghoon Lee, Annalyn Welp, Manoj Chelvanambi, Matthew Lastrapes, Heng Liu, Zhe Yuan, Chen Wang, Hao Nie, Stephanie Jean, Luis J. Montaner, Jiakai Hou, Ami Patel, Shrina Patel, Bryan Fellman, Ying Yuan, Baohua Sun, Renganayaki Krishna Pandurengan, Edwin Roger Parra Cuentas, Joseph Celestino, Yan Liu, Jinsong Liu, R. Tyler Hillman, Shannon N. Westin, Anil K. Sood, Pamela T. Soliman, Aaron Shafer, Larissa A. Meyer, David M. Gershenson, David Vining, Dhakshinamoorthy Ganeshan, Karen Lu, Jennifer A. Wargo, Weiyi Peng, Rugang Zhang, Linghua Wang and Amir A. Jazaeri

Loss of colonic fidelity enables multilineage plasticity and metastasis pp. 547-556

Patrizia Cammareri, Michela Raponi, Yourae Hong, Caroline V. Billard, Nat Peckett, Yujia Zhu, Fausto D. Velez-Bravo, Nicholas T. Younger, Donnchadh S. Dunican, Sebastian Ö.-G. Pohl, Aslihan Bastem Akan, Nora J. Doleschall, John Falconer, Mark White, Jean Quinn, Kathryn Pennel, Roberta Garau, Sudhir B. Malla, Philip D. Dunne, Richard R. Meehan, Owen J. Sansom, Joanne Edwards, Malcolm G. Dunlop, Farhat V. N. Din, Sabine Tejpar, Colin W. Steele and Kevin B. Myant

Mapping and engineering RNA-driven architecture of the multiphase nucleolus pp. 557-566

Sofia A. Quinodoz, Lifei Jiang, Aya A. Abu-Alfa, Troy J. Comi, Hongbo Zhao, Qiwei Yu, Lennard W. Wiesner, Jordy F. Botello, Anita Donlic, Elizabeth Soehalim, Prashant Bhat, Christiane Zorbas, Ludivine Wacheul, Andrej Košmrlj, Denis L. J. Lafontaine, Sebastian Klinge and Clifford P. Brangwynne

Scientific bedlam at the world’s weirdest and wildest research conference pp. 567-568

Josie Glausiusz

Six questions to ask before jumping into a spreadsheet pp. 569-570

Stephanie Melchor

How does agricultural land become forest? I trek to find out pp. 572-572

Dave Tacon

2025, volume 644, articles 8075

Inconclusive proof of ferroelectricity in peptide-VDF ribbons pp. E1-E3

Maximilian Litterst, Andrey Alekseevich Butkevich and Martijn Kemerink

Reply to: Inconclusive proof of ferroelectricity in peptide-VDF ribbons pp. E4-E6

Yang Yang, Hiroaki Sai, Simon A. Egner, Ruomeng Qiu, Liam C. Palmer and Samuel I. Stupp

Data anomalies and the economic commitment of climate change pp. E7-E11

Tom Bearpark, Dylan Hogan and Solomon Hsiang

Why suppressing all wildfires has made today’s megafires worse pp. 9-9

Jason Sharples

Author Correction: Stress dynamically modulates neuronal autophagy to gate depression onset pp. E12-E12

Liang Yang, Chen Guo, Zhiwei Zheng, Yiyan Dong, Qifeng Xie, Zijian Lv, Min Li, Yangyang Lu, Xiaonan Guo, Rongshan Deng, Yiqin Liu, Yirong Feng, Ruiqi Mu, Xuliang Zhang, Huan Ma, Zhong Chen, Zhijun Zhang, Zhaoqi Dong, Wei Yang, Xiangnan Zhang and Yihui Cui

Powerful satellite will map changes on Earth in stunning detail — down to a centimetre pp. 13-14

Alexandra Witze

Columbia researchers eager to restart science after university’s deal with Trump pp. 14-15

Jenna Ahart and Alexandra Witze

How to tackle research misconduct: survey finds stark disagreement pp. 16-17

Miryam Naddaf

The brain fires up immune cells when sick people are nearby pp. 17-17

Katie Kavanagh

How China’s bold talent recruitment has shaped science pp. 18-19

Smriti Mallapaty

Mystery food in Neanderthal diet might be maggots pp. 19-20

Jenna Ahart

DeepMind and OpenAI models solve maths problems at level of top students pp. 20-20

Davide Castelvecchi

This company claimed to ‘de-extinct’ dire wolves. Then the fighting started pp. 21-23

Ewen Callaway

The peer-review crisis: how to fix an overloaded system pp. 24-27

David Adam

‘The Sun had fallen to Earth’ — a survivor’s recollection of the Hiroshima bombing pp. 29-32

Mordecai Sheftall

Environmental politics is doomed to fail — unless we tell better stories pp. 32-34

Philip Macnaghten

To save lives in heatwaves, focus on how human bodies work pp. 35-38

Ollie Jay, Jennifer Vanos, Daniel Gagnon and Federico Tartarini

We need a new ethics for a world of AI agents pp. 38-40

Iason Gabriel, Geoff Keeling, Arianna Manzini and James Evans

Conserve marine migratory species to protect ecological links between land and sea pp. 41-41

Géraldine Lassalle, Patrick Lambert, Audrey M. Darnaude and Pedro Raposo de Almeida

Protect Palestinian archaeological sites during war pp. 41-41

Loay Abu Alsaud

Breed giant prawns to withstand disease and climate change pp. 41-41

Fengbo Li and Qiang Gao

Plan-B careers can be a force for good in science pp. 41-41

Kathleen A. Marrs

Overcome threats to renewable energy through skilful statecraft pp. 42-42

Sangeetha Chandrashekeran, Adam Fish, Elizabeth Thurbon and Benjamin K. Sovacool

Don’t train medical AI on patients’ data without their knowledge pp. 42-42

Toral Banerjee, Rongyu Lin and Mengyuan Shi

Protection from biological hazards at work arrives at last pp. 42-42

Gunter Kathagen

Tackle fake citations generated by AI pp. 42-42

Ayyoob Sharifi

The tiny mouse lemur could make for a mighty model organism pp. 43-44

J. Gray Camp

Homo sapiens adapted to diverse habitats before successfully populating Eurasia pp. 44-46

William E. Banks

Neuronal transfer of mitochondria to tumour cells promotes cancer spread pp. 46-47

Anand K. Singh and Yuan Pan

AI learns from nature to design super-adhesive gels that work underwater pp. 47-48

Laura Russo

Merging of magnetic plasma ‘flux ropes’ is driven by turbulence pp. 48-50

Jeffersson Agudelo Rueda

The science fiction science method pp. 51-58

Iyad Rahwan, Azim Shariff and Jean-François Bonnefon

Kinetic turbulence drives MHD equilibrium change via 3D reconnection pp. 59-63

Jong Yoon Park, Young Dae Yoon and Yong-Seok Hwang

Coherent spectroscopy with a single antiproton spin pp. 64-68

B. M. Latacz, S. R. Erlewein, M. Fleck, J. I. Jäger, F. Abbass, B. P. Arndt, P. Geissler, T. Imamura, M. Leonhardt, P. Micke, A. Mooser, D. Schweitzer, F. Voelksen, E. Wursten, H. Yildiz, K. Blaum, J. A. Devlin, Y. Matsuda, C. Ospelkaus, W. Quint, A. Soter, J. Walz, Y. Yamazaki, C. Smorra and S. Ulmer

High-accuracy laser spectroscopy of $${{\bf{H}}}_{{\bf{2}}}^{{\boldsymbol{+}}}$$ H 2 + and the proton–electron mass ratio pp. 69-75

S. Alighanbari, M. R. Schenkel, V. I. Korobov and S. Schiller

Long-range hyperbolic polaritons on a non-hyperbolic crystal surface pp. 76-82

Lu Liu, Langlang Xiong, Chongwu Wang, Yihua Bai, Weiliang Ma, Yupeng Wang, Peining Li, Guogang Li, Qi Jie Wang, Francisco J. Garcia-Vidal, Zhigao Dai and Guangwei Hu

Magnon spectroscopy in the electron microscope pp. 83-88

Demie Kepaptsoglou, José Ángel Castellanos-Reyes, Adam Kerrigan, Júlio Alves do Nascimento, Paul M. Zeiger, Khalil El Hajraoui, Juan Carlos Idrobo, Budhika G. Mendis, Anders Bergman, Vlado K. Lazarov, Ján Rusz and Quentin M. Ramasse

Data-driven de novo design of super-adhesive hydrogels pp. 89-95

Hongguang Liao, Sheng Hu, Hu Yang, Lei Wang, Shinya Tanaka, Ichigaku Takigawa, Wei Li, Hailong Fan and Jian Ping Gong

Redox-powered autonomous directional C–C bond rotation under enzyme control pp. 96-101

Jordan Berreur, Olivia F. B. Watts, Theo H. N. Bulless, Nicholas T. O’Donoghue, Marc Olmo, Ashley J. Winter, Jonathan Clayden and Beatrice S. L. Collins

Modular arene functionalization by differential 1,2-diborylation pp. 102-108

Jingfeng Huo, Yue Fu, Melody J. Tang, Ya Su, Shengkun Hu, Peng Liu and Guangbin Dong

Invariance of dynamo action in an early-Earth model pp. 109-114

Yufeng Lin, Philippe Marti and Andrew Jackson

Major expansion in the human niche preceded out of Africa dispersal pp. 115-121

Emily Y. Hallett, Michela Leonardi, Jacopo Niccolò Cerasoni, Manuel Will, Robert Beyer, Mario Krapp, Andrew W. Kandel, Andrea Manica and Eleanor M. L. Scerri

Ancient DNA reveals the prehistory of the Uralic and Yeniseian peoples pp. 122-132

Tian Chen Zeng, Leonid A. Vyazov, Alexander Kim, Pavel Flegontov, Kendra Sirak, Robert Maier, Iosif Lazaridis, Ali Akbari, Michael Frachetti, Alexey A. Tishkin, Natalia E. Ryabogina, Sergey A. Agapov, Danila S. Agapov, Anatoliy N. Alekseev, Gennady G. Boeskorov, Anatoly P. Derevianko, Viktor M. Dyakonov, Dmitry N. Enshin, Alexey V. Fribus, Yaroslav V. Frolov, Sergey P. Grushin, Alexander A. Khokhlov, Kirill Yu. Kiryushin, Yurii F. Kiryushin, Egor P. Kitov, Pavel Kosintsev, Igor V. Kovtun, Nikolai P. Makarov, Viktor V. Morozov, Egor N. Nikolaev, Marina P. Rykun, Tatyana M. Savenkova, Marina V. Shchelchkova, Vladimir Shirokov, Svetlana N. Skochina, Olga S. Sherstobitova, Sergey M. Slepchenko, Konstantin N. Solodovnikov, Elena N. Solovyova, Aleksandr D. Stepanov, Aleksei A. Timoshchenko, Aleksandr S. Vdovin, Anton V. Vybornov, Elena V. Balanovska, Stanislav Dryomov, Garrett Hellenthal, Kenneth Kidd, Johannes Krause, Elena Starikovskaya, Rem Sukernik, Tatiana Tatarinova, Mark G. Thomas, Maxat Zhabagin, Kim Callan, Olivia Cheronet, Daniel Fernandes, Denise Keating, Francesca Candilio, Lora Iliev, Aisling Kearns, Kadir Toykan Özdoğan, Matthew Mah, Adam Micco, Megan Michel, Iñigo Olalde, Fatma Zalzala, Swapan Mallick, Nadin Rohland, Ron Pinhasi, Vagheesh M. Narasimhan and David Reich

The mutagenic forces shaping the genomes of lung cancer in never smokers pp. 133-144

Marcos Díaz-Gay, Tongwu Zhang, Phuc H. Hoang, Charles Leduc, Marina K. Baine, William D. Travis, Lynette M. Sholl, Philippe Joubert, Azhar Khandekar, Wei Zhao, Christopher D. Steele, Burçak Otlu, Shuvro P. Nandi, Raviteja Vangara, Erik N. Bergstrom, Mariya Kazachkova, Oriol Pich, Charles Swanton, Chao Agnes Hsiung, I-Shou Chang, Maria Pik Wong, Kin Chung Leung, Jian Sang, John P. McElderry, Caleb Hartman, Frank J. Colón-Matos, Mona Miraftab, Monjoy Saha, Olivia W. Lee, Kristine M. Jones, Pilar Gallego-García, Yang Yang, Xiaoming Zhong, Eric S. Edell, Jacobo Martínez Santamaría, Matthew B. Schabath, Sai S. Yendamuri, Marta Manczuk, Jolanta Lissowska, Beata Świątkowska, Anush Mukeria, Oxana Shangina, David Zaridze, Ivana Holcatova, Dana Mates, Sasa Milosavljevic, Millica Kontic, Yohan Bossé, Bonnie E. Gould Rothberg, David C. Christiani, Valerie Gaborieau, Paul Brennan, Geoffrey Liu, Paul Hofman, Lixing Yang, Martin A. Nowak, Jianxin Shi, Nathaniel Rothman, David C. Wedge, Robert Homer, Soo-Ryum Yang, Angela C. Pesatori, Dario Consonni, Qing Lan, Bin Zhu, Stephen J. Chanock, Jiyeon Choi, Ludmil B. Alexandrov and Maria Teresa Landi

An instantaneous voice-synthesis neuroprosthesis pp. 145-152

Maitreyee Wairagkar, Nicholas S. Card, Tyler Singer-Clark, Xianda Hou, Carrina Iacobacci, Lee M. Miller, Leigh R. Hochberg, David M. Brandman and Sergey D. Stavisky

Spatial transcriptomics reveals human cortical layer and area specification pp. 153-163

Xuyu Qian, Kyle Coleman, Shunzhou Jiang, Andrea J. Kriz, Jack H. Marciano, Chunyu Luo, Chunhui Cai, Monica Devi Manam, Emre Caglayan, Abbe Lai, David Exposito-Alonso, Aoi Otani, Urmi Ghosh, Diane D. Shao, Rebecca E. Andersen, Jennifer E. Neil, Robert Johnson, Alexandra LeFevre, Jonathan L. Hecht, Nicola Micali, Nenad Sestan, Pasko Rakic, Michael B. Miller, Liang Sun, Carsen Stringer, Mingyao Li and Christopher A. Walsh

Astrocyte morphogenesis requires self-recognition pp. 164-172

John H. Lee, Alina P. Sergeeva, Göran Ahlsén, Seetha Mannepalli, Fabiana Bahna, Kerry M. Goodman, Runzhe Xu, Baljit S. Khakh, Joshua A. Weiner, Lawrence Shapiro, Barry Honig and S. Lawrence Zipursky

A molecular cell atlas of mouse lemur, an emerging model primate pp. 173-184

Camille Ezran, Shixuan Liu, Stephen Chang, Jingsi Ming, Olga Botvinnik, Lolita Penland, Alexander Tarashansky, Antoine Morree, Kyle J. Travaglini, Jia Zhao, Gefei Wang, Kazuteru Hasegawa, Hosu Sin, Rene Sit, Jennifer Okamoto, Rahul Sinha, Yue Zhang, Caitlin J. Karanewsky, Jozeph L. Pendleton, Maurizio Morri, Martine Perret, Fabienne Aujard, Lubert Stryer, Steven Artandi, Margaret T. Fuller, Irving L. Weissman, Thomas A. Rando, James E. Ferrell, Bo Wang, Iwijn Vlaminck, Can Yang, Kerriann M. Casey, Megan A. Albertelli, Angela Oliveira Pisco, Jim Karkanias, Norma Neff, Angela Ruohao Wu, Stephen R. Quake and Mark A. Krasnow

Mouse lemur cell atlas informs primate genes, physiology and disease pp. 185-196

Camille Ezran, Shixuan Liu, Stephen Chang, Jingsi Ming, Lisbeth A. Guethlein, Michael F. Z. Wang, Roozbeh Dehghannasiri, Julia Olivieri, Hannah K. Frank, Alexander Tarashansky, Winston Koh, Qiuyu Jing, Olga Botvinnik, Jane Antony, Angela Oliveira Pisco, Jim Karkanias, Can Yang, James E. Ferrell, Scott D. Boyd, Peter Parham, Jonathan Z. Long, Bo Wang, Julia Salzman, Iwijn Vlaminck, Angela Ruohao Wu, Stephen R. Quake and Mark A. Krasnow

Functional amyloid proteins confer defence against predatory bacteria pp. 197-204

Hannah E. Ledvina, Ryan Sayegh, Ricardo O. Carale, A. Maxwell Burroughs, Alexa R. Macklin, Ashley L. Azadeh, Layla D. Borja Najera, L. Aravind and Aaron T. Whiteley

R9AP is a common receptor for EBV infection in epithelial cells and B cells pp. 205-213

Yan Li, Hua Zhang, Cong Sun, Xiao-Dong Dong, Chu Xie, Yuan-Tao Liu, Ruo-Bin Lin, Xiang-Wei Kong, Zhu-Long Hu, Xiao-Yan Ma, Dan-Ling Dai, Qian-Ying Zhu, Yu-Chun Li, Ying Li, Shang-Xin Liu, Li Yuan, Peng-Hui Zhou, Song Gao, Ya-Ping Tang, Jin-Ying Yang, Ping Han, Andrew T. McGuire, Bo Zhao, Jin-Xin Bei, Erle Robertson, Yi-Xin Zeng, Qian Zhong and Mu-Sheng Zeng

Targeting de novo purine biosynthesis for tuberculosis treatment pp. 214-220

Dirk A. Lamprecht, Richard J. Wall, Annelies Leemans, Barry Truebody, Joke Sprangers, Patricia Fiogbe, Cadi Davies, Jennefer Wetzel, Stijn Daems, William Pearson, Vanessa Pillay, Samantha Saylock, M. Daniel Ricketts, Ellie Davis, Adam Huff, Tsehai Grell, Shiming Lin, Michelle Gerber, Ann Vos, John Dallow, Sam J. Willcocks, Christine Roubert, Stéphanie Sans, Amandine Desorme, Nicolas Chappat, Aurélie Ray, Mariana Pereira Moraes, Tracy Washington, Hope D’Erasmo, Pavankumar Sancheti, Melissa Everaerts, Mario Monshouwer, Jorge Esquivias, Gerald Larrouy-Maumus, Ruxandra Draghia Akli, Helen Fletcher, Alexander S. Pym, Bree B. Aldridge, Jansy P. Sarathy, Kathleen W. Clancy, Bart Stoops, Neeraj Dhar, Adrie J. C. Steyn, Paul Jackson, Clara Aguilar-Pérez and Anil Koul

Detecting structural heart disease from electrocardiograms using AI pp. 221-230

Timothy J. Poterucha, Linyuan Jing, Ramon Pimentel Ricart, Michael Adjei-Mosi, Joshua Finer, Dustin Hartzel, Christopher Kelsey, Aaron Long, Daniel Rocha, Jeffrey A. Ruhl, David vanMaanen, Marc A. Probst, Brock Daniels, Shalmali D. Joshi, Olivier Tastet, Denis Corbin, Robert Avram, Joshua P. Barrios, Geoffrey H. Tison, I-Min Chiu, David Ouyang, Alexander Volodarskiy, Michelle Castillo, Francisco A. Roedan Oliver, Paloma P. Malta, Siqin Ye, Gregg F. Rosner, Jose M. Dizon, Shah R. Ali, Qi Liu, Corey K. Bradley, Prashant Vaishnava, Carol A. Waksmonski, Ersilia M. DeFilippis, Vratika Agarwal, Mark Lebehn, Polydoros N. Kampaktsis, Sofia Shames, Ashley N. Beecy, Deepa Kumaraiah, Shunichi Homma, Allan Schwartz, Rebecca T. Hahn, Martin Leon, Andrew J. Einstein, Mathew S. Maurer, Heidi S. Hartman, John Weston Hughes, Christopher M. Haggerty and Pierre Elias

A coordinated cellular network regulates tolerance to food pp. 231-240

Anna Rudnitsky, Hanna Oh, Maya Margolin, Bareket Dassa, Inbar Shteinberg, Liat Stoler-Barak, Ziv Shulman and Ranit Kedmi

Rewiring endogenous genes in CAR T cells for tumour-restricted payload delivery pp. 241-251

Amanda X. Y. Chen, Kah Min Yap, Joelle S. Kim, Kevin Sek, Yu-Kuan Huang, Phoebe A. Dunbar, Volker Wiebking, Jesse D. Armitage, Isabelle Munoz, Kirsten L. Todd, Emily B. Derrick, Dat Nguyen, Junming Tong, Cheok Weng Chan, Thang X. Hoang, Katherine M. Audsley, Marit J. Elsas, Jim Middelburg, Joel N. Lee, Maria N. Menezes, Thomas J. Cole, Jasmine Li, Christina Scheffler, Andrew M. Scott, Laura K. Mackay, Jason Waithman, Jane Oliaro, Simon J. Harrison, Ian A. Parish, Junyun Lai, Matthew H. Porteus, Imran G. House, Phillip K. Darcy and Paul A. Beavis

Nerve-to-cancer transfer of mitochondria during cancer metastasis pp. 252-262

Gregory Hoover, Shila Gilbert, Olivia Curley, Clémence Obellianne, Mike T. Lin, William Hixson, Terry W. Pierce, Joel F. Andrews, Mikhail F. Alexeyev, Yi Ding, Ping Bu, Fariba Behbod, Daniel Medina, Jeffrey T. Chang, Gustavo Ayala and Simon Grelet

Taurine from tumour niche drives glycolysis to promote leukaemogenesis pp. 263-272

Sonali Sharma, Benjamin J. Rodems, Cameron D. Baker, Christina M. Kaszuba, Edgardo I. Franco, Bradley R. Smith, Takashi Ito, Kyle Swovick, Kevin Welle, Yi Zhang, Philip Rock, Francisco A. Chaves, Sina Ghaemmaghami, Laura M. Calvi, Archan Ganguly, W. Richard Burack, Michael W. Becker, Jane L. Liesveld, Paul S. Brookes, Joshua C. Munger, Craig T. Jordan, John M. Ashton and Jeevisha Bajaj

Interactions between TTYH2 and APOE facilitate endosomal lipid transfer pp. 273-279

Anastasiia Sukalskaia, Andreas Karner, Anna Pugnetti, Florian Weber, Birgit Plochberger and Raimund Dutzler

The role of metabolism in shaping enzyme structures over 400 million years pp. 280-289

Oliver Lemke, Benjamin Murray Heineike, Sandra Viknander, Nir Cohen, Feiran Li, Jacob Lucas Steenwyk, Leonard Spranger, Federica Agostini, Cory Thomas Lee, Simran Kaur Aulakh, Judith Berman, Antonis Rokas, Jens Nielsen, Toni Ingolf Gossmann, Aleksej Zelezniak and Markus Ralser

Retraction Note: Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis pp. 290-290

Zaili Luo, Mingyang Xia, Wei Shi, Chuntao Zhao, Jiajia Wang, Dazhuan Xin, Xinran Dong, Yu Xiong, Feng Zhang, Kalen Berry, Sean Ogurek, Xuezhao Liu, Rohit Rao, Rui Xing, Lai Man Natalie Wu, Siying Cui, Lingli Xu, Yifeng Lin, Wenkun Ma, Shuaiwei Tian, Qi Xie, Li Zhang, Mei Xin, Xiaotao Wang, Feng Yue, Haizi Zheng, Yaping Liu, Charles B. Stevenson, Peter Blank, John P. Perentesis, Richard J. Gilbertson, Hao Li, Jie Ma, Wenhao Zhou, Michael D. Taylor and Q. Richard Lu

The COVID-19 pandemic transformed this scientist into a research-integrity sleuth pp. 291-293

Christine Ro

Is your AI benchmark lying to you? pp. 294-296

Michael Brooks

How I’m electrifying transportation in Tanzania pp. 298-298

Nikki Forrester