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2026, volume 654, articles 8120

My diverse academic background is affecting my PhD studies — what do I do? pp. 1119-1120

Xiaoying You

My overseas job offer was rescinded. Here’s how I bounced back pp. 1120-1121

Andrew Kythreotis

2026, volume 654, articles 8119

Author Correction: US oil and gas system emissions from nearly one million aerial site measurements pp. E16-E16

Evan D. Sherwin, Jeffrey S. Rutherford, Zhan Zhang, Yuanlei Chen, Erin B. Wetherley, Petr V. Yakovlev, Elena S. F. Berman, Brian B. Jones, Daniel H. Cusworth, Andrew K. Thorpe, Alana K. Ayasse, Riley M. Duren and Adam R. Brandt

Author Correction: Hidden states and dynamics of fractional fillings in twisted MoTe2 bilayers pp. E17-E17

Yiping Wang, Jeongheon Choe, Eric Anderson, Weijie Li, Julian Ingham, Eric A. Arsenault, Yiliu Li, Xiaodong Hu, Takashi Taniguchi, Kenji Watanabe, Xavier Roy, Dmitri Basov, Di Xiao, Raquel Queiroz, James C. Hone, Xiaodong Xu and X.-Y. Zhu

Author Correction: Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant pp. E18-E18

Rigel Suzuki, Daichi Yamasoba, Izumi Kimura, Lei Wang, Mai Kishimoto, Jumpei Ito, Yuhei Morioka, Naganori Nao, Hesham Nasser, Keiya Uriu, Yusuke Kosugi, Masumi Tsuda, Yasuko Orba, Michihito Sasaki, Ryo Shimizu, Ryoko Kawabata, Kumiko Yoshimatsu, Hiroyuki Asakura, Mami Nagashima, Kenji Sadamasu, Kazuhisa Yoshimura, The Genotype to Phenotype Japan (G2P-Japan) Consortium, Hirofumi Sawa, Terumasa Ikeda, Takashi Irie, Keita Matsuno, Shinya Tanaka, Takasuke Fukuhara and Kei Sato

Author Correction: CHIT1-positive microglia drive motor neuron ageing in the primate spinal cord pp. E19-E19

Shuhui Sun, Jiaming Li, Si Wang, Jingyi Li, Jie Ren, Zhaoshi Bao, Le Sun, Xibo Ma, Fangshuo Zheng, Shuai Ma, Liang Sun, Min Wang, Yan Yu, Miyang Ma, Qiaoran Wang, Zhiyuan Chen, He Ma, Xuebao Wang, Zeming Wu, Hui Zhang, Kaowen Yan, Yuanhan Yang, Yixin Zhang, Sheng Zhang, Jinghui Lei, Zhao-Qian Teng, Chang-Mei Liu, Ge Bai, Yan-Jiang Wang, Jian Li, Xiaoqun Wang, Guoguang Zhao, Tao Jiang, Juan Carlos Izpisua Belmonte, Jing Qu, Weiqi Zhang and Guang-Hui Liu

Publisher Correction: White matter micro- and macrostructure brain charts for the human lifespan pp. E20-E20

Michael E. Kim, Chenyu Gao, Karthik Ramadass, Nancy R. Newlin, Praitayini Kanakaraj, Sam Bogdanov, Gaurav Rudravaram, Derek Archer, Timothy J. Hohman, Angela L. Jefferson, Victoria L. Morgan, Alexandra Roche, Dario J. Englot, Susan M. Resnick, Lori L. Beason-Held, Laurie E. Cutting, Laura A. Barquero, Micah A. D’archangel, Tin Q. Nguyen, Kathryn L. Humphreys, Yanbin Niu, Sophia Vinci-Booher, Carissa J. Cascio, The HABS-HD Study Team, L. Taylor Davis, Zhiyuan Li, Simon N. Vandekar, Panpan Zhang, John C. Gore, Bennett A. Landman and Kurt G. Schilling

Editorial Expression of Concern: Functional proteomic identification of DNA replication proteins by induced proteolysis in vivo pp. E21-E21

Masato Kanemaki, Alberto Sanchez-Diaz, Agnieszka Gambus and Karim Labib

I advise the Vatican and the UN on AI — don’t dismiss the Pope’s message as theology pp. 573-573

Paolo Benanti

AI has entered the workforce: tax tech profits, not people pp. 574-574

Ljubica Nedelkoska

Precise genome editing of human embryos triggers praise and alarm pp. 577-578

Mohana Basu, Edward Chen and Heidi Ledford

Why are so many young people getting cancer? What researchers do and don’t know pp. 578-579

Heidi Ledford

Human migration has surged since 2000 — these maps reveal where people are going pp. 580-581

Miryam Naddaf

Nuclear-fusion firm says plant will deliver electricity to grid — but big questions remain pp. 581-582

Elizabeth Gibney

Chinese detector edges closer to solving the mystery of neutrino mass pp. 582-583

Davide Castelvecchi

World-first: therapy to make cells young again trialled in a person pp. 583-583

Heidi Ledford

See a helicopter destined for Mars and a spectacular flowery frame for the Milky Way — May’s best science images pp. 584-584

Davide Castelvecchi

These ‘master’ proteins protect us from deadly mutations — and could inspire new drugs pp. 586-588

Philip Ball

Tech titans are hacking their bodies for a longer life: is there science behind their methods? pp. 589-591

Chris Stokel-Walker

Why people should work together to shape the economy pp. 592-594

Clara Mattei

How AI is revealing the secret lives of animals from hummingbirds to pumas pp. 594-596

Ryan Huling

World Cup: science must tackle footballers’ mental and physical health pp. 597-598

David Adam

Transistors on a roll: 3D circuits built from stacks of flexible membranes pp. 599-600

Veeresh Deshpande

Organ formation in early human embryos captured in spatial cell atlas pp. 600-602

Varun K. A. Sreenivasan and Malte Spielmann

Hybrid refinery process turns plant material into industrially important chemical pp. 602-603

Micaela Chacón and Neil Dixon

What a royal bedchamber provides the queen bee pp. 603-605

Michael L. Smith

Mitochondria tethered to the nucleus secure its energy supply pp. 605-606

Philippa Clarke and Sophie Trefely

People are turning to AI chatbots to plug gaps in health information pp. 607-608

Moritz Gerstung

Emergent decadal predictability in Antarctic contribution to sea-level rise pp. 609-613

Felicity S. McCormack, Mathieu Morlighem, Frank Pattyn, Alexander A. Robel and Hélène Seroussi

A distant brown dwarf coplanar to a warm Jupiter and a hot super-Earth pp. 614-618

Matías I. Jones, Luca Naponiello, Trifon Trifonov, Rafael Brahm, Gabriele Pichierri, Lorena Acuña-Aguirre, Robert J. De Rosa, Marcelo Tala Pinto, Aldo S. Bonomo, Luigi Mancini, Alessandro Sozzetti, Yared Reinarz, Alessandro Morbidelli, Néstor Espinoza, Giovanni Rosotti, Eric L. Nielsen, Stefan Y. Stefanov, Thomas Henning, Andrés Jordán, Jan Eberhardt, Artie Hatzes, Leonardo Vanzi, Jan Janik and Petr Kabath

Nuclear shell structure governs short-range nucleon pairing pp. 619-621

D. Nguyen, C. Yero, H. Szumila-Vance, F. Hauenstein, N. Swan, L. B. Weinstein, J. Kahlbow, G. A. Miller, A. Schmidt, E. Piasetzky, O. Hen, C. Ayerbe Gayoso, E. Cohen, P. Datta, A. Denniston, B. R. Devkota, M. Diefenthaler, C. Fogler, B. R. Gamage, D. Higinbotham, I. Korover, C. Morean, M. Nycz, M. Satnik, S. Seeds, P. Sharp, M. Suresh, A. S. Tadepalli, R. Wagner and E. W. Wertz

A prototype differential atom interferometer for fundamental physics pp. 622-628

C. F. A. Baynham, R. Hobson, O. Buchmüller, D. Evans, L. Hawkins, L. Iannizzotto Venezze, A. Josset, D. Lee, E. Pasatembou, B. E. Sauer, M. R. Tarbutt, T. Walker, O. Ennis, U. Chauhan, A. Brzakalik, S. Dey, S. Hedges, B. Stray, M. Langlois, K. Bongs, T. Hird, S. Lellouch, M. Holynski, B. Bostwick, J. Chen, Z. Eyler, V. Gibson, T. L. Harte, C. C. Hsu, M. Karzazi, C. Lu, B. Millward, J. Mitchell, N. Mouelle, B. Panchumarthi, J. Scheper, U. Schneider, X. Su, Y. Tang, K. Tkalčec, M. Zeuner, S. Zhang, Y. Zhi, L. Badurina, A. Beniwal, D. Blas, J. Carlton, J. Ellis, C. McCabe, G. Parish, D. Pathak Govardhan, V. Vaskonen, T. Bowcock, K. Bridges, A. Carroll, J. Coleman, G. Elertas, S. Hindley, C. Metelko, H. Throssell, J. N. Tinsley, E. Bentine, M. Booth, D. Bortoletto, N. Callaghan, C. Foot, C. Gómez-Monedero, K. Hughes, A. James, T. Leese, A. Lowe, J. March-Russell, J. Sander, J. Schelfhout, I. Shipsey, D. Weatherill, D. Wood, S. N. Balashov, M. G. Bason, K. Hussain, H. Labiad, P. Majewski, A. L. Marchant, D. Newbold, Z. Pan, Z. Tam, T. C. Thornton, T. Valenzuela, M. G. D. van der Grinten, I. Wilmut, K. Clarke, A. Vick and Collaboration Aion

Two-component exciton condensates in an electron–hole bilayer pp. 629-634

Ruishi Qi, Qize Li, Jiahui Nie, Ruichen Xia, Haleem Kim, Hyungbin Lim, Jingxu Xie, Takashi Taniguchi, Kenji Watanabe, Michael F. Crommie, Allan H. MacDonald and Feng Wang

Probing picometre-scale interlayer deformations via hyperbolic polaritons pp. 635-641

Shu Zhang, Xiangdong Guo, Xiaowen Zhang, Jiashu Yang, Qinzheng Yu, Zhengyang Mou, Bingze Wu, Chenchen Wu, Shiyu Yang, Yongxin Lan, Peiyi He, Jing Shi, Kaijun Feng, Yuxiang Gao, Qiang Zheng, Shuang Zhang, F. Javier García de Abajo, Zhipei Sun, Mingguang Yao, Feng Ding, Peng Gao, Xiaoxia Yang and Qing Dai

Efficient and accurate neural-field reconstruction using resistive memory pp. 642-651

Yifei Yu, Xinyuan Zhang, Shaocong Wang, Woyu Zhang, Xiuzhe Wu, Yangu He, Jichang Yang, Yue Zhang, Ning Lin, Bo Wang, Xi Chen, Songqi Wang, Xiaoshan Wu, Shihao Han, Yi Li, Meng Xu, Hegan Chen, Wenkui Zhang, Jingyi Chen, Xumeng Zhang, Xiaojuan Qi, Dashan Shang, Qi Liu, Zhongrui Wang, Kwang-Ting Cheng and Ming Liu

Monolithic three-dimensional integration of silicon transistors pp. 652-659

Bao Lam, Yung Man Yu, Hyunjun Nam, Hsu-Chih Ni, Shomik Chatterjee, Shaloo Rakheja, Jian-Min Zuo and Qing Cao

Stereoelectronic manipulation of ligands for perovskite solar cells pp. 660-667

Tinghuan Yang, Erxin Zhao, Nan Wu, Xiaoming Chang, Chenqing Tian, Hai-Long Wang, Lu Zhang, Nannan Gu, Ting Nie, Ye Yang, Zheng Zhang, Tianfei Xu, Xin Chen, Shuang Wang, Tianqi Niu, Niansheng Xu, Chuang Ma, Haojin Li, Buyi Yan, Zicheng Ding, Shengzhong Frank Liu, Feng Gao and Kui Zhao

Lignin to adipic acid in a high-yield chemical and biological redox process pp. 668-675

Kathryn M. Mains, Chad T. Palumbo, Davide Rigo, Matthew S. Webber, Gloria Rosetto, Si Tong Bao, Austin L. Carroll, Nicolette R. Meyer, Alexander F. Benson, Brett A. Boyle, Stefan J. Haugen, Morgan A. Ingraham, William G. Alexander, Miriam Silberman, Logan C. Myers, Kelsey J. Ramirez, Kevin P. Sullivan, Adam M. Guss, Davinia Salvachúa, Yuriy Román-Leshkov, Shannon S. Stahl, Allison Z. Werner and Gregg T. Beckham

Earth’s east–west albedo symmetry pp. 676-682

Jianhao Zhang, Jake J. Gristey and Graham Feingold

Pollinators support the nutrition and income of vulnerable communities pp. 683-688

T. P. Timberlake, S. Sapkota, N. M. Saville, A. R. Cirtwill, S. C. Baral, D. R. Bhusal, K. Devkota, S. Giri, H. A. Harris-Fry, D. Joshi, S. Kortsch, S. S. Myers, T. Roslin, M. R. Smith and J. Memmott

Queen cell architecture shapes honey bee queen development pp. 689-696

Yu Fang, Beibei Ma, Xiaolu Jin, Anja Buttstedt, Yahya Al Naggar, Kathy Darragh, Huafeng Tian, Yin Zhu, Guan Yang, Yiying Yang, Yuan Huang, Wanli Li, Rumeng Xu, Jianke Li, Fuliang Hu, Liming Wu, Wenjun Peng, Xiaofeng Xue, Boris Baer and Kai Wang

Lethal plague outbreaks in Lake Baikal hunter-gatherers 5,500 years ago pp. 697-705

Ruairidh Macleod, Frederik V. Seersholm, Bianca De Sanctis, Angela Lieverse, Adrian Timpson, Rick Schulting, Jesper T. Stenderup, Charleen Gaunitz, Lasse Vinner, Olga Ivanovna Goriunova, Vladimir Ivanovich Bazaliiskii, Sergei V. Vasilyev, Erin Jessup, Yucheng Wang, Christopher Bronk Ramsey, Mark G. Thomas, Russell Corbett-Detig, Astrid K. N. Iversen, Andrzej W. Weber, Martin Sikora and Eske Willerslev

Chromosomal fusions trigger rediploidization of autopolyploid genomes pp. 706-713

Chuanshuai Xie, Zitu Ma, Chaowei Zhou, Kexin Ma, Haoyu Wang, Jiahong Wu, Yan Zhou, Yongrui Lu, Da Ji, Xuedie Gu, He Gao, Junting Li, Suxing Fu, Weiqiang Li, Zhaofang Han, Shijun Xiao, Fei Liu, Benhe Zeng, Sheng’ao Chen, Jiangong Niu, Tao Zhang, Jian Shen, Chunna Liu, Jing Luo, Daniel J. Macqueen, Axel Meyer, Haiping Liu and Luohao Xu

Plasticity and language in the anaesthetized human hippocampus pp. 714-723

Kalman A. Katlowitz, Eric R. Cole, Elizabeth A. Mickiewicz, Shraddha Shah, Melissa Franch, Joshua A. Adkinson, James L. Belanger, Raissa K. Mathura, Domokos Meszéna, Matthew McGinley, William Muñoz, Garrett P. Banks, Sydney S. Cash, Chih-Wei Hsu, Angelique C. Paulk, Nicole R. Provenza, Andrew J. Watrous, Ziv Williams, Alica M. Goldman, Vaishnav Krishnan, Atul Maheshwari, Sarah R. Heilbronner, Robert Kim, Nuttida Rungratsameetaweemana, Benjamin Y. Hayden and Sameer A. Sheth

Flexible ensheathment of axons enables myelination of complex CNS networks pp. 724-733

Cody L. Call, Sarah A. Neely, Jason J. Early, Owen G. James, Lida Zoupi, Anna C. Williams, Yu Kang T. Xu, Siddharthan Chandran, David A. Lyons, Kelly R. Monk and Dwight E. Bergles

Developmental organization of sensory and sympathetic ganglia pp. 734-743

Keng Ioi Vong, Yanina D. Alvarez, Qingquan Zhang, Jiaming Weng, Geoffroy Noel, Scott T. Barton, Changuk Chung, Robyn Howarth, Naomi Meave, Fiza Jiwani, Sai B. Patarlapalli, Fenyong Yao, Fugui Zhu, Chelsea Barrows, Arzoo Patel, Jian Xiong Wang, Neil C. Chi, Stephen F. Kingsmore, Melanie D. White, Xiaoxu Yang and Joseph G. Gleeson

Active dissociation of intracortical spiking and high gamma activity pp. 744-750

Tianhao Lei, Michael R. Scheid, Robert D. Flint, Joshua I. Glaser and Marc W. Slutzky

Spatiotemporal transcriptome atlas of human embryos after gastrulation pp. 751-761

Jiexue Pan, Yuejiao Li, Zhongliang Lin, Qing Lan, Ying Zhang, Huixi Chen, Shengwei Sui, Man Zhai, Gaochen Zhang, Yi Cheng, Yunhui Tang, Qingchen Wang, Yue Xu, Guoling Li, Chunyan Xu, Haoqi Yan, Yiting Mao, Xingxia Wang, Hao Li, Yiping Zhu, Qinfang Chen, Yichun Guan, Nan Meng, Chang Wang, Haiqian Lu, Xiangjuan Li, Tingting Zheng, Xiaoying Yao, Tingyu Yang, Xuan Chen, Qiuyu Qin, Bin Jiang, Yuxing Ren, Xinmei Liu, Yuxin Zhang, Minghui Yu, Lifang Wang, Yanrong Wei, Meiqi Luo, Ji Nancuo, Fuhe Ma, Ziwei Wang, Zhihua Ou, Ying Lei, Xin Jin, Jianzhong Sheng, Congjian Xu, Yanting Wu, Chenming Xu, Lijian Zhao, Hongbo Yang, Ya Gao, Guolian Ding, Xun Xu and Hefeng Huang

Steric hindrance of antibody binding in an Omicron spike fusion intermediate pp. 762-770

Zhiheng Bao, Zhimin Liu, Zhaoyong Zhang, Xuanjia Wang, Xiaohui Jin, Jiaxiu Bai, Hanwen Ma, Yaxin Li, Chunyan Yi, Zhiyang Ling, Zhong Huang, Lu Zhang, Zhenguo Chen, Youhua Xie, Yanqun Wang, Lei Sun and Xiaoyu Sun

Translation-dependent degradation of cas12 mRNA triggered by an anti-CRISPR pp. 771-776

Nicole D. Marino, Alexander Talaie, Milan Gerovac, Jorge L. Rodriguez, Andrew D. Schmidt, Theresa J. Astmann, Héloïse Carion, Anya Flood Taylor, Jessica Liliedahl, Surabhi Haniyur, Kristi Zoga, Matthew C. Johnson, Leandro Buhlmann, Kuei-Ho Chen, Sukrit Silas, Li Yuping, Yang Zhang, Danielle L. Swaney, Jörg Vogel and Joseph Bondy-Denomy

Vaccination generates broadly cross-neutralizing antibodies to the HIV Env apex pp. 777-785

Javier Guenaga, Monika Ádori, Shridhar Bale, Swastik Phulera, Ioannis Zygouras, Fabian-Alexander Schleich, Xaquin Castro Dopico, Sashank Agrawal, Miyo Ota, Richard Wilson, Jocelyn Cluff, Tamar Dzvelaia, Marco Mandolesi, Wen-Hsin Lee, Agnes A. Walsh, Mariane B. Melo, Laurent Verkoczy, Darrell J. Irvine, Martin Corcoran, Ian A. Wilson, Diane Carnathan, Guido Silvestri, Andrew B. Ward, Gabriel Ozorowski, Gunilla B. Karlsson Hedestam and Richard T. Wyatt

Mitochondria directly interact with the nuclear pore complex pp. 786-797

Ivan Menendez-Montes, Consuelo Marin-Vicente, Shibani Mukherjee, Mahmoud Salama Ahmed, Manuel Jose Gomez, Chukwuemeka George Anene-Nzelu, Chang Jie Mick Lee, Svenja Koslowski, Ashley Solmonson, Tara Tassin, Shah R. Ali, Pedro Pessoa, Abdallah Elnwasany, Nicholas T. Lam, Suwannee Thet, Enrique Calvo, Alisson C. Cardoso, Ana Helena M. Pereira, Feng Xiao, Ping Wang, Asim Mohamed, Hamed El-feky, Ahmed Elghamry, Gonzalo Gancedo-Alonso, Ngoc Uyen Nhi Nguyen, Ching-Cheng Hsu, Aundrea K. Westfall, Ralph DeBerardinis, Roger Sik-Yin Foo, Michael Kinter, Steve Pressé, Chao Xing, Luke Szweda, Asaithamby Aroumougame, Fatima Sanchez-Cabo, Jose Antonio Enriquez, Miguel Torres, Jesus Vazquez and Hesham A. Sadek

Netrin1 blockade alleviates resistance to chemotherapy in pancreatic cancer pp. 798-805

Gael Roth, Pascal Artru, Olivier Bouche, Nicolas Williet, Julien Ghelfi, Anthony Turpin, Astrid Lievre, Jean-Frédéric Blanc, Camille Evrard, Jean-Baptiste Bachet, Pauline Parent, Marc Manceau, Matthieu Roustit, Anna Borowik, Victoire Granger, Aurélie Durand, Christelle d’Engremont, Edouard Girard, Mircea Chirica, Nicolas Braissand, Nicolas Rama, Eugénie Modolo, Hector Hernandez-Vargas, Elise Georges, Jean-Yves Scoazec, Jerome Cros, Sébastien Hazard, Benjamin Ducarouge, Thomas Decaens, Agnès Bernet and Patrick Mehlen

Prime assembly with linear DNA donors enables large genomic insertions pp. 806-812

Bin Liu, Andrew Petti, Xuntao Zhou, Haoyang Cheng, Jenny Gao, Matthew Yee, Youwei Qiao, Yanjun Zhang, Lin Zhou, Scot A. Wolfe, Tingting Jiang, Erik J. Sontheimer and Wen Xue

Expanding the human proteome with microproteins and peptideins pp. 813-825

Eric W. Deutsch, Leron W. Kok, Jonathan M. Mudge, Cristian F. Valls, Irwin Jungreis, Jorge Ruiz-Orera, Zhi Sun, Ulrike Kusebauch, Ivo Fierro-Monti, Jennifer G. Abelin, M. Mar Alba, Julie L. Aspden, Sreejan Bandyopadhyay, Kaushik Banerjee, Pavel V. Baranov, Ariel A. Bazzini, Francis Bourassa, Elspeth A. Bruford, Lorenzo Calviello, Steven A. Carr, Anne-Ruxandra Carvunis, Sonia Chothani, Jim Clauwaert, Kellie Dean, Pouya Faridi, Adam Frankish, Amy Goodale, Thomas Green, Norbert Hubner, Nicholas T. Ingolia, Manolis Kellis, Michele Magrane, Maria Jesus Martin, Thomas F. Martinez, Gerben Menschaert, Uwe Ohler, Sandra Orchard, Alisa Potter, Owen J. L. Rackham, Matthew G. Rees, David E. Root, Jennifer A. Roth, Xavier Roucou, Fernando J. Sialana, Sarah A. Slavoff, Michał I. Świrski, Jack A. S. Tierney, Félix-Antoine Trifiro, Eivind Valen, Valeriia Vasylieva, Aaron Wacholder, Shengbo Wang, Li Wang, Jonathan S. Weissman, Wei Wu, Zhi Xie, Jyoti S. Choudhary, Michal Bassani-Sternberg, Juan Antonio Vizcaíno, Nicola Ternette, Marie A. Brunet, Robert L. Moritz, John R. Prensner and Sebastiaan van Heesch

Let’s talk about biomedical research kits pp. 827-828

Rao M. Uppu

Seven steps for critically analysing research papers pp. 828-829

Jacques Cornwell

In the field — and in the lab — sometimes the simplest tool is best pp. 830-831

Amanda Heidt

The Haber–Bosch fertilizer production process should be taught through a social-ecological lens pp. 834-834

Jianjun Wu

El Niño in a thermally saturated world pp. 834-834

Carlos García-Soto

Terms of endearment? Bias in first-name eponyms for species named after people pp. 834-834

Elizabeth J. Carlen, Jonathan B. Losos and Samantha E. E. Kreling

2026, volume 654, articles 8118

When drug discovery fails: scientists share their frustrations with the process pp. S1-S3

Tammy Worth

Author Correction: In vitro characterization of the human segmentation clock pp. E13-E13

Margarete Diaz-Cuadros, Daniel E. Wagner, Christoph Budjan, Alexis Hubaud, Oscar A. Tarazona, Sophia Donelly, Arthur Michaut, Ziad Al Tanoury, Kumiko Yoshioka-Kobayashi, Yusuke Niino, Ryoichiro Kageyama, Atsushi Miyawaki, Jonathan Touboul and Olivier Pourquié

Author Correction: Satellite megaconstellations will threaten space-based astronomy pp. E14-E14

Alejandro S. Borlaff, Pamela M. Marcum and Steve B. Howell

Author Correction: Modelling late gastrulation in stem cell-derived monkey embryo models pp. E15-E15

Jie Li, Jie Li, Jing Cao, ShenShen Shang, Liansheng Zhang, Fei Gao, Jiqiang Fu, Hongyu Chen, Guizhong Cui, Haoyuan Wu, Xiaolong Wang, Alfonso Martinez-Arias, Qiang Sun and Zhen Liu

Gen Z scepticism towards AI is a wake-up call — universities must take it seriously pp. 299-299

Mim Rahimi

Don’t compete, collaborate: why collective funding applications are the future pp. 300-300

Sajedeh Rasti

Science sleuths uncover more than 100 suspicious images in Thermo Fisher antibody catalogue pp. 303-304

Dan Garisto

Poor supervision is pushing young researchers out of academia pp. 304-305

Mohana Basu

Gene therapies to fix failing hearts gain steam after years in the doldrums pp. 305-306

Edward Chen

Polymarket vs science: why researchers are sceptical of the prediction-market hype pp. 307-308

Jenna Ahart

Microsoft upgrades controversial quantum chip — researchers are still sceptical pp. 308-309

Davide Castelvecchi

Feynman solved the ‘restaurant dilemma’ 50 years ago — now a study confirms his mathematics pp. 309-310

Davide Castelvecchi

Bang! Exploding immune cells splatter potent toxins everywhere pp. 310-310

Amanda Heidt

Is the peptide craze backed by science? The promise behind the hype pp. 312-314

Cassandra Willyard

How ice forms is a mystery — now scientists are cracking the case pp. 315-317

Mark Buchanan

Sustainability or dystopia? What past patterns tell us about where society is heading pp. 318-320

David Armstrong McKay

The best way to start your day? The science backs naked cartwheels in the sun pp. 320-322

Gareth Thompson

Vanishing tongues and life on Mars: Books in brief pp. 322-322

Andrew Robinson

Bridget Ogilvie obituary: parasitologist who championed biomedical labs and scientific evidence pp. 323-323

Anne Cooke

How AI is reshaping discovery in maths and physics pp. 324-326

Mikhail Burtsev, Yang-Hui He, Evgeny Sobko, Ananyo Bhattacharya and Thore Graepel

Becoming a mother leaves long-lasting molecular memories pp. 327-328

Frances A. Champagne

Child sexual abuse enabled by digital technologies is widespread and under-reported pp. 328-330

Xiangming Fang and Greta M. Massetti

JUNO experiment ushers in next generation of neutrino experiments pp. 330-331

Patricia Vahle and Zoya Vallari

Nests in an egg cell: structures of protein-storage units in oocytes pp. 332-333

Matthias Geyer and Gregor Hagelueken

Quantum light source boosts attosecond science pp. 333-335

Jan Marcus Dahlström

Fifty years since a simple equation described the chaos of biology pp. 335-336

Michael P. H. Stumpf and Zoë Laidlaw

Building user-driven climate adaptation products pp. 337-342

Nabig A. Chaudhry, William D. Collins, David Anthoff and Andrew D. Jones

Measurement of reactor neutrino oscillation with the first JUNO data pp. 343-348

The JUNO Collaboration

Improved quantum processor logical error rates via correction and detection pp. 349-355

A. Paetznick, B. W. Reichardt, M. P. da Silva, C. Ryan-Anderson, D. Aasen, J. M. Bello-Rivas, J. P. Campora, R. Chao, A. Chernoguzov, W. van Dam, J. M. Dreiling, C. Foltz, F. Frachon, J. P. Gaebler, T. M. Gatterman, L. Grans-Samuelsson, D. Gresh, D. Hayes, N. Hewitt, C. Holliman, C. V. Horst, J. Johansen, D. Lucchetti, Y. Matsuoka, M. Mills, S. A. Moses, B. Neyenhuis, A. Paz, J. Pino, P. Siegfried, A. Sundaram, D. Tom, Z. Wang, S. J. Wernli, M. Zanner, R. P. Stutz and K. M. Svore

Nonlinear atomic tunnelling boosted by bright squeezed vacuum pp. 356-360

Zhejun Jiang, Shengzhe Pan, Jianqi Chen, Mingyu Zhu, Chenhao Zhao, Yiwen Wang, Ru Zhang, Jianshi Lu, Lulu Han, Suwen Xiong, Dian Wu, Wenxue Li, Shicheng Jiang, Hongcheng Ni and Jian Wu

Cavity-driven attractive interactions in quantum materials pp. 361-368

F. Helmrich, H. S. Adlong, M. Kroner, I. Khanonkin, G. Scalari, J. Faist, A. İmamoğlu and T. F. Nova

Chiral superfluorescence from perovskite superlattices at room temperature pp. 369-374

Qi Wei, Jonah S. Peter, Hui Ren, Weizhen Wang, Luwei Zhou, Qi Liu, Stefan Ostermann, Jun Yin, Songhua Cai, Susanne F. Yelin and Mingjie Li

In situ nanocrystal confinement for efficient blue perovskite LEDs pp. 375-382

Shaocheng Liu, Mike Pols, Zhongyang Zhang, Xudan Huang, Zijian Huang, Ying Han, Zhenyu Guo, Liang Li, Rundong Fan, Zhang De-Yi, Du Ping, Wenjin Yu, Jiazhen Gu, Luxuan Men, Hao Dong, Shuxia Tao, Lifen Wang, Qi Chen, Huan Wang, Huaiyu Xu, Ling-Dong Sun, Chun-Hua Yan and Huanping Zhou

Analysis of trade-offs of post-sorting plastic packaging pp. 383-390

Alexandra Schmuck, Tiago G. A. Belé, Daniël Withoeck, Kevin M. Van Geem, Kim Ragaert and Steven De Meester

Temporary carbon dioxide removal to offset short-lived climate forcers pp. 391-397

Yue He, Keywan Riahi, Matthew J. Gidden, Shilong Piao, Tao Wang and Thomas Gasser

Decade-long warming accelerates antibiotic resistance in grassland soils pp. 398-407

Linwei Wu, Da-Shuai Mu, Jing An, Yanan Wang, Xiaomin Fan, Lu De-Chen, Ya Zhang, Yinan Xie, Jonathan Michael, Daniel Curtis, Yupeng Fan, Yajiao Wang, Xue Guo, Qichao Tu, Qingyun Yan, Qun Gao, Zhili He, Ye Deng, Kai Xue, Liyou Wu, Daliang Ning, Xuanyu Tao, Yunfeng Yang and Jizhong Zhou

Technology mediation in child sexual exploitation and abuse in Africa and Asia pp. 408-418

Sakshi Ghai, Matti Vuorre, Daniel Kardefelt-Winther, Amanda M. Ferguson, Sebastian Kurten, Sonia Livingstone, Andrew K. Przybylski and Amy Orben

Ancient DNA reveals pervasive directional selection across West Eurasia pp. 419-428

Ali Akbari, Annabel Perry, Alison R. Barton, Mohammadreza Kariminejad, Steven Gazal, Zheng Li, Yating Zeng, Alissa Mittnik, Nick Patterson, Matthew Mah, Xiang Zhou, Alkes L. Price, Eric S. Lander, Ron Pinhasi, Nadin Rohland, Swapan Mallick and David Reich

Saturation editing of RNU4-2 reveals distinct dominant and recessive disorders pp. 429-436

Joachim De Jonghe, Hyung Chul Kim, Ayanfeoluwa Adedeji, Elsa Leitão, Ruebena Dawes, Christina M. Kajba, Benjamin Cogné, Yuyang Chen, Alexander J. M. Blakes, Cas Simons, Rocio Rius, Javeria R. Alvi, Florence Amblard, Christina Austin-Tse, Sarah Baer, Elsa V. Balton, Pierre Blanc, Daniel G. Calame, Charles Coutton, Chloe A. Cunningham, Nitsuh Dargie, Katrina M. Dipple, Haowei Du, Salima El Chehadeh, Ian Glass, Joseph G. Gleeson, Olivier Grunewald, Paul Gueguen, Radu Harbuz, Marie-Line Jacquemont, Richard J. Leventer, Pierre Marijon, Olfa Messaoud, Tipu Sultan, Christel Thauvin, Catherine Vincent-Delorme, Elif Yilmaz Gulec, Julien Thevenon, Rodrigo Mendez, Daniel G. MacArthur, Christel Depienne, Caroline Nava, Nicola Whiffin and Gregory M. Findlay

Dynamics of genetic and somatic trade-offs in ageing and mortality pp. 437-453

Danny Arends, David G. Ashbrook, Suheeta Roy, Lu Lu, Zachary Sloan, Arthur G. Centeno, Kurt H. Lamour, João Pedro de Magalhães, Pjotr Prins, Karl W. Broman, Saunak Sen, Sarah J. Mitchell, Michael R. MacArthur, Özlem Altintas Akin, Xiaoxu Li, Amandeep Bajwa, Vivian Diaz, David E. Harrison, Randy Strong, James F. Nelson, Khyobeni Mozhui, Johan Auwerx, Evan G. Williams, Richard A. Miller and Robert W. Williams

Shared neural substrates of prosocial and parenting behaviours pp. 454-464

Fangmiao Sun, Kayla Y. Lim, James Dang, Li I. Zhang, Ye Emily Wu and Weizhe Hong

Dopamine drives persistent remodelling of the maternal brain pp. 465-475

Jennifer C. O’Chan, Giuseppina Di Salvo, Ashley M. Cunningham, Sohini Dutta, Elizabeth Brindley, Benjamin H. Weekley, Winnie Chen, Rasika R. Iyer, Ethan Wan, Cindy Zhang, Naguib Mechawar, Gustavo Turecki and Ian Maze

Aversive learning hijacks a brain sugar sensor to consolidate memory pp. 476-484

Raquel Francés, Typhaine Comyn, Coraline Desnous, Francesca Bettoni, Alice Pavlowsky, Thomas Preat and Pierre-Yves Plaçais

mRNA vaccines engage unconventional pathways in CD8+ T cell priming pp. 485-494

Suin Jo, Lijin Li, Chandrani Thakur, Kevin A. Telfer, Hussein Sultan, Ray A. Ohara, Michelle He, Giri Nam, Jing Chen, Feiya Ou, Monia Draghi, Nicholas M. Valiante, Robert D. Schreiber, Gwendalyn J. Randolph, Naresha Saligrama, Theresa L. Murphy, William E. Gillanders and Kenneth M. Murphy

Submicrometre sampling of living cells by macrophages pp. 495-503

Amy C. Fan, Rukman R. Thota, Nina Serwas, Vivasvan S. Vykunta, Kyle Marchuk, Megan K. Ruhland, Lauren Liu, Grace Johnson, Austin Edwards and Matthew F. Krummel

A pro-carcinogenic bacterial toxin binds claudin-4 to cleave E-cadherin pp. 504-512

Maxwell T. White, Kang Wang, Hailong Zhang, Ulrich Eckhard, Karthik Hullahalli, Jason Chen, Shaoguang Wu, Abby L. Geis, Jie Zhang, Jessica Queen, F. Xavier Gomis-Ruth, Matthew K. Waldor, Min Dong and Cynthia L. Sears

Pervasive and programmed nucleosome distortion on single chromatin fibres pp. 513-522

Marty G. Yang, Hannah J. Richter, Simai Wang, Colin P. McNally, Camille M. Moore, Ali Emadi, Nicole E. Harris, Simaron Dhillon, Michela Maresca, Huimin Pan, Hayden Saunders, Ruiqiao Yang, Megan S. Ostrowski, Erika C. Anderson, Elzo de Wit, Jacquelyn J. Maher, Yuhong Fan, Geeta J. Narlikar, Elphège P. Nora, Holger Willenbring, Hani Goodarzi and Vijay Ramani

Structure of the mouse cytoplasmic lattice pp. 523-531

Pengliang Chi, Xiang Wang, Jialu Li, Jingrui Huang, Sicheng Ju, Sibei Liu, Li Yan, Yuechao Lu, Zihan Zhang, Zhuo Han, Jinhong Li, Qianqian Qi, Qingting Liu, Yiren Zeng, Li Guo, Xiaofeng Zhang, Long Gui and Dong Deng

Molecular basis of oocyte cytoplasmic lattice assembly pp. 532-540

Shuxian Liu, Yusong Liu, Junchao Xue, Zhenzhen Li, Yan Zhang, Bailun Li, Lidan Xu, Lili Li, Zhenzhen Yu, Hongtao Yu, Haishan Gao and En-Zhi Shen

Cytoplasmic lattices are megadalton storage complexes in mammalian oocytes pp. 541-546

Zeynep Ilgın Kılıç, Joyce van Loenhout, Marten Chaillet, Robert M. van Es, Paula Sobrevals Alcaraz, Harmjan R. Vos, Willem E. M. Noteborn and Miguel Ricardo Leung

Structural basis of fungal β-1,3-glucan synthase inhibition by caspofungin pp. 547-555

Zhenning Ren, Abhishek Chhetri, Chang Liu, ShuYu Offner, Kedar Sharma, Mario J. Borgnia, Wonpil Im, Kenichi Yokoyama and Seok-Yong Lee

Five winning images of scientists at work pp. 557-559

Alexia Austin

AI is taking on antibiotic resistance — here’s how pp. 560-562

Jyoti Madhusoodanan

Arson attacks at Ebola hospitals are a cry for regional development pp. 564-564

Dieudonne Mwamba, John Ditekemena and Shahul H. Ebrahim

Preventing cancer requires more than a list of carcinogens pp. 564-564

Hossein Akbarialiabad, Iltefat H. Hamzavi, Abrar A. Qureshi and Jane M. Grant-Kels

AI technology must serve human cognitive development, not the other way around pp. 564-564

Jianjun Wu

Science must be seen as a viable profession for the many, not the few pp. 564-564

Roy D. Sleator

2026, volume 654, articles 8117

The size of tropical vegetation gross primary production pp. E1-E4

Jie Tian, Xiaojuan Huang, Huilin Chen, Jing Ming Chen, Philippe Ciais, Maarten Krol, Shunlin Liang, Shilong Piao, Jin Wu, Jingfeng Xiao, Xiuzhi Chen and Wenping Yuan

Reply to: The size of tropical vegetation gross primary production pp. E5-E7

Jiameng Lai, Linda M. J. Kooijmans, Wu Sun, Danica Lombardozzi, J. Elliott Campbell, Lianhong Gu, Yiqi Luo, Le Kuai and Ying Sun

Author Correction: The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis pp. E8-E8

Trevor P. Fidler, Chenyi Xue, Mustafa Yalcinkaya, Brian Hardaway, Sandra Abramowicz, Tong Xiao, Wenli Liu, David G. Thomas, Mohammad Ali Hajebrahimi, Joachim Pircher, Carlos Silvestre-Roig, Andriana G. Kotini, Larry L. Luchsinger, Ying Wei, Marit Westerterp, Hans-Willem Snoeck, Eirini P. Papapetrou, Christian Schulz, Steffen Massberg, Oliver Soehnlein, Benjamin Ebert, Ross L. Levine, Muredach P. Reilly, Peter Libby, Nan Wang and Alan R. Tall

Better diagnostics could have limited this Ebola outbreak pp. 9-9

Kevin K. Ariën

Author Correction: Postprandial lipid metabolism durably enhances T cell immunity pp. E9-E9

Alok Kumar, Dayana B. Rivadeneira, Isha Mehta, Bingxian Xie, Rachel Cumberland, Supriya K. Joshi, Jitendra S. Kanshana, William G. Gunn, Victoria Dean, Angelina Parise, Kristin Morder, Erica S. Myers, Steven J. Mullett, Richard T. Cattley, Stacy L. Gelhaus, Abigail E. Overacre-Delgoffe, Jishnu Das, William F. Hawse, Alison B. Kohan and Greg M. Delgoffe

Why a synthetic human genome is still worth building pp. 10-10

Sudarshan Pinglay

Author Correction: Inactivating SnRK1β1A promotes broad-spectrum disease resistance in rice pp. E10-E10

Guixin Yuan, Xunli Lu, Xingbin Wang, Mengfei Li, Shiwei Wang, Zhaoxiang Huang, Zhigang Li, Fengrui Zhang, Xin Zhang, Jun Yang, Hailong Guo, Vijai Bhadauria, Wang-Sheng Zhu, Wensheng Zhao, Meng Yuan, Jian-Min Zhou and You-Liang Peng

Publisher Correction: GLP-1R–GIPR–PPARα/γ/δ quintuple agonism corrects obesity and diabetes in mice pp. E11-E11

Daniela Liskiewicz, Aaron Novikoff, Ahmed Khalil, Seun Akindehin, Jonathan E. Campbell, Pietra Candela, Russell L. Castelino, Callum Coupland, Maxime Culot, W. Scott Dodson, Jonathan D. Douros, Hannes Embring, Annette Feuchtinger, Brian Finan, Cristina Garcia-Caceres, Xiao-Bing Gao, Fabien Gosselet, Gerald Grandl, Robert M. Gutgesell, Daniel T. Haas, Martin Jastroch, Ezgi Karaoglu, Pamela Kakimoto, Anna Cristina Kaltenbach, Michaela Keuper, Christine M. Kusminski, Danielle C. Leander, Arkadiusz Liskiewicz, Xue Liu, Gandhari Maity-Kumar, Sara Martinez Martinez, Stephanie A. Mowery, Ruben Nogueiras, Marshall Paisley, Diego Perez-Tilve, Patricia S. S. Petersen, Paul T. Pfluger, Sneha Prakash, Sabine Steffens, Alberto Cebrian-Serrano, Monica Tost, Jordan Wean, Christian Weber, Junichi Yoshida, Zachary Gerhart-Hines, Tamas L. Horvath, Philipp E. Scherer, Randy J. Seeley, Richard D. DiMarchi, Matthias H. Tschöp, Natalie Krahmer, Patrick J. Knerr and Timo D. Müller

Publisher Correction: Microbiota-induced T cell plasticity enables immune-mediated tumour control pp. E12-E12

Tariq A. Najar, Yuan Hao, Yuhan Hao, Gabriela Romero-Meza, Alexandra Dolynuk, Emma Almo and Dan R. Littman

Move over, AlphaFold: open-source model predicts shape of 1 billion proteins pp. 13-14

Ewen Callaway and Miryam Naddaf

Robots run this laboratory in Japan — and are changing how scientists work pp. 14-15

Rachel Fieldhouse

AI cracks 80-year-old mathematics challenge — researchers are astonished pp. 15-16

Davide Castelvecchi

Ebola outbreak spirals out of control: how might it have started? pp. 16-17

Mohana Basu

See the clouds streaming and vanishing around this planet — 690 light years away pp. 17-18

Davide Castelvecchi

Stress impairs your brain’s ability to link memories — dampening insight pp. 18-18

Simon Spichak

Blue Origin rocket explosion rattles NASA’s mission to put humans back on the Moon pp. 19-20

Alexandra Witze

Tough peer-review process? Your paper might end up being more highly cited pp. 20-20

Mariana Lenharo

Will AI ruin the social sciences — or revolutionize them? pp. 22-24

David Adam

Can an army of babies and dogs rescue psychology from its reproducibility crisis? pp. 26-28

Nic Fleming

How long can humans live? We simply don’t know pp. 29-31

David Adam

Peter H. Raven obituary: visionary botanist who transformed our understanding of plant diversity pp. 32-32

Lúcia G. Lohmann

Obesity doesn’t equate to ill health: why the ‘disease’ label doesn’t always fit pp. 33-36

Francesco Rubino

Robust projections of risks to the Amazon rainforest pp. 37-38

Chris Huntingford

Jupiter observations reveal a simple scaling law for particle acceleration pp. 38-39

Martin E. Pessah

Gene-expression patterns can be used to estimate mortality risk and chronological age pp. 40-41

João Pedro de Magalhães

Nanostructure of tooth enamel casts light on dietary shifts as humans evolved pp. 41-43

Alejandro Romero

Protective maternal gut instincts pp. 43-45

Jiahui Sun and Sing Sing Way

Hard-to-detect mutations explain how common autoimmune diseases arise pp. 45-46

Sergei B. Koralov and Timothy C. Borbet

Relativistic electron acceleration at the bow shock of Jupiter and beyond pp. 47-51

Savvas Raptis, Drew L. Turner, Damiano Caprioli, Jamey R. Szalay, George Clark and Colby C. Haggerty

Direct observation of the superallowed α-decay of 104Te pp. 52-56

Ian Cox, Robert Grzywacz, T. T. King, K. P. Rykaczewski, S. Nishimura, R. Yokoyama, N. Fukuda, N. Kitamura, S. Go, C. Mazzocchi, J. M. Allmond, A. Augustyn, N. Braukman, P. Brionnet, A. Esmaylzadeh, J. Fischer, G. Garcia de Lorenzo, S. Hanai, D. Hoskins, N. Imai, K. Kolos, A. Korgul, B. Kreider, S. Michimasa, K. Nishio, V. Phong, T. J. Ruland, H. Sakurai, Y. Shimizu, A. Skruch, H. Suzuki, H. Takeda, Y. Togano, Z. Y. Xu and M. Yoshimoto

High-pulse-energy integrated mode-locked laser using a Mamyshev oscillator pp. 57-63

Zheru Qiu, Xuan Yang, Xurong Li, Jianqi Hu, Zhongshu Liu, Yichi Zhang, Xinru Ji, Jiale Sun, Grigory Lihachev, Zihan Li, Ulrich Kentsch and Tobias J. Kippenberg

Metamaterial-enhanced near-field radiative heat transfer pp. 64-68

Zexiao Wang, Renwen Yu, Hakan Salihoglu, Xiao Luo, Zhuo Li, Hyeonggyun Kim, Xiu Liu, Tianyi Huang, Yibai Zhong, Shanhui Fan and Sheng Shen

Continuously graded-doped SnO2 for efficient n–i–p perovskite solar cells pp. 69-75

Di Wang, Saisai Li, Zijin Ding, Jian Xu, Xingyu Chen, Qiao Zheng, Thamraa Alshahrani, Siyu Liu, Tingwei He, Xinxin Yue, Saif M. H. Qaid, Keyu Wei, Xuewen Fu, Lin Feng, Ou Yang, Huanxin Ju, Yuanzhi Jiang, Jun Chen and Mingjian Yuan

Enamel nanocrystal misorientation increased with meat-eating and agriculture pp. 76-84

Pupa U. P. A. Gilbert, Daniel R. Green, Patrick Mahoney, Debbie Guatelli-Steinberg, W. Scott McGraw, Emma Lagan, Fredrick Kyalo Manthi, Samuel Muteti, Emmanuel Ndiema, Fernando Ramirez Rozzi, Cayla A. Stifler, Connor A. Schmidt, Barat Q. Achinuq, Andreas Scholl, Benjamin Gilbert and Mackie C. O’Hara

Mechanophore cross-linking enhances ballistic energy dissipation of polymers pp. 85-91

Zhen Sang, Suong T. Nguyen, Kwangwook Ko, Senpeng Lin, Heecheol Jang, Simon Gonzalez-Zapata, Sullivan Fitz, Yun Kai, Steven Kooi, Chuting Deng, Monica Olvera de la Cruz, Marisol Koslowski, Heather J. Kulik, Stephen L. Craig, Keith A. Nelson and Jeremiah A. Johnson

Ambiphilic cross-coupling with aryl-bismuth reagents pp. 92-99

Byeongdo Roh, Benedict A. Williams and Josep Cornella

Enhanced response of extreme compound events to cumulative CO2 emissions pp. 100-106

Jun Li, Yao Zhang, Philippe Ciais, Hongying Zhang, Zhaoli Wang, Hongwu Tang and Shilong Piao

Forest carbon protocols underestimate climate-driven carbon loss risks pp. 107-113

Chao Wu, Grayson Badgley, Michael L. Goulden, James T. Randerson, Anna T. Trugman, Jonathan A. Wang, Linqing Yang, Nezha Acil, Susan C. Cook-Patton, Danny Cullenward, Steven J. Davis, Christopher A. Williams and William R. L. Anderegg

Deforestation-induced drying lowers Amazon climate threshold pp. 114-120

Nico Wunderling, Boris Sakschewski, Johan Rockström, Bernardo M. Flores, Marina Hirota and Arie Staal

The 1000 Chinese Pangenome empowers medical and population genetics pp. 121-130

Yifei Wang, Zhongqu Duan, Dan Chen, Dandan Shi, Yi Ding, Zhibin Wang, Baoqing Li, Zhiyi Wang, Minmin Guo, Wen Yang, Junren Hou, Wenhao Chen, Yazhou Guo, Wenjie Wei, Yujie Cao, Xiwei Sun, Weiyang Bai, Mingdong Lu, Ting Qi, Xian Shen and Jian Yang

Polyclonal selection of immune checkpoint mutations in thyroid autoimmunity pp. 131-141

Pantelis A. Nicola, Andrew R. J. Lawson, Alexandra Tidd, Juliette Imbert, Yoshihiro Ishida, Luke A. Wylie, Paul A. Scott, Kenny Roberts, Luke M. R. Harvey, Stefanie V. Lensing, Wei Cheng, Federico Abascal, Daniel Leongamornlert, Yvette Hooks, Matthew Mayho, Nicole Müller-Sienerth, Sara Widaa, Laura Mincarelli, James Illing, Flavia Peci, Bee Ling Ng, Georgeina L. Jarman, Andrew J. C. Russell, Krishnaa T. A. Mahbubani, Kourosh Saeb-Parsy, Anna L. Paterson, Krishna Chatterjee, Raheleh Rahbari, Omer Ali Bayraktar, Michael R. Stratton, Peter J. Campbell, John A. Tadross, Nadia Schoenmakers and Iñigo Martincorena

Deconstruction of a spino-brain–spinal cord circuit that drives chronic pain pp. 142-151

Qian Wang, Joo Han Lee, Gregory Nachtrab, Yuan Yuan, Lei Yuan, Wei Qi, Manuel A. Mohr, Jing Xiong, Mark A. Horowitz and Xiaoke Chen

Neural representation of action symbols in primate frontal cortex pp. 152-162

Lucas Y. Tian, Kedar Garzón Gupta, Daniel J. Hanuska, Adam G. Rouse, Mark A. G. Eldridge, Marc H. Schieber, Xiao-Jing Wang, Joshua B. Tenenbaum and Winrich A. Freiwald

Dopaminergic mechanisms of dynamical social specialization pp. 163-172

C. Solié, A. Nicolson, R. Justo, Y. Layadi, B. Morin, C. Batifol, L. M. Reynolds, T. Le Borgne, S. L. Fayad, A. Gulmez, Y. Rodriguez Quevedo, J. Allegret-Vautrot, G. Centene Guglielmi, F. de Chaumont, S. Didienne, N. Debray, J.-P. Hardelin, B. Girard, A. Mourot, J. Naudé, C. Viollet, F. Marti, B. Delord and Ph. Faure

Universal transcriptomic hallmarks of mammalian ageing and mortality pp. 173-188

Alexander Tyshkovskiy, Daria Kholdina, Maria Davitadze, Adrian Molière, Alibek Moldakozhayev, Yoshiyasu Tongu, Tomoko Kasahara, Dmitrii Glubokov, Alec Eames, Leonid M. Kats, Anastasiya Vladimirova, Kejun Ying, Hanna Liu, Bohan Zhang, Uma Khasanova, Mahdi Moqri, Jeremy M. Van Raamsdonk, David E. Harrison, Randy Strong, Takaaki Abe, Sergey E. Dmitriev and Vadim N. Gladyshev

Cytoplasmic competition between separate parental pronuclei in zygotes pp. 189-197

Hirohisa Kyogoku, Mitsusuke Tarama, Masahiro Matsuwaka, Tappei Mishina, Akihito Harada, Reiko Nakagawa, Mami Kumon, Yoshihiro Shimizu, Yasuyuki Ohkawa, Tatsuo Shibata, Azusa Inoue and Tomoya S. Kitajima

Glycerol-driven TNAP activation in thermogenesis and mineralization pp. 198-208

Mohammed Faiz Hussain, Shreya S. Krishnan, Brittany L. Carroll, Bozena Samborska, Aisha Mousa, Alice Williamson, Maria Delgado-Martin, Bindu Y. Srinivasu, Jakub Bunk, Janane F. Rahbani, Abel Oppong, Anna Roesler, Zafir Kaiser, Mina Ersin, Qiaoqiao Zhang, Maria Guerra Martinez, Abhirup Shaw, Jonathan Cheng, Hannah Klemets, Katalin Kocsis Illes, Victoria E. DeMambro, Clifford J. Rosen, José Luis Millán, Thomas E. Wales, Claudia Langenberg, Marc D. McKee, Alba Guarné and Lawrence Kazak

Eosinophils drive intestinal remodelling and innate defence in reproduction pp. 209-218

Chenyan Huang, Amanda Sun, Jojo Reyes, Jessica Ribeiro de Souza, Thomas R. Cafiero, Krist H. Antunes Fernandes, Fabricio Marcus Silva Oliveira, Yujie Qiao, Pedro Gazzinelli-Guimaraes, Yuri Pritykin and Ai Ing Lim

DNA damage drives antigen diversification in Trypanosoma brucei pp. 219-228

Jaclyn E. Smith, Kevin J. Wang, Erin M. Kennedy, Jane C. Munday, Lulu Singer, Jill M. C. Hakim, Jaime So, Alexander K. Beaver, Aishwarya Magesh, Shane D. Gilligan-Steinberg, Jessica Zheng, Bailin Zhang, Dharani Narayan Moorthy, Zachary E. Brown, Elgin Henry Akin, Lusajo Mwakibete, Richard McCulloch and Monica R. Mugnier

Emergence of oncofetal plasticity is ubiquitous in early colorectal cancers pp. 229-239

Julian R. Buissant des Amorie, Joris H. Hageman, Sascha R. Brunner, Suzanne E. M. van der Horst, Maria C. Puschhof, Arne van Hoeck, Inge van Lierop, Sjors Middelkamp, Lisa van der Schee, Sven van Kempen, Folkert Morsink, Robin Geene, Sander Mertens, David S. Cavigelli, Ingrid Verlaan-Klink, Lianne J. Kraaier, Jorieke Salij, Renate Bezemer, Onno Kranenburg, Miangela M. Laclé, Leon M. G. Moons and Hugo J. G. Snippert

Myosin forces remodel F-actin for mechanosensitive protein recognition pp. 240-249

Ayala G. Carl, Matthew J. Reynolds, Xiaoyu Sun, Pinar S. Gurel, Donovan Y. Z. Phua, Keith Hamilton, Lin Mei, John W. Watters, Yasuharu Takagi, Alex J. Noble, James R. Sellers and Gregory M. Alushin

Template-driven scaffolding of SCFFBXO42 regulates PP2A degradation pp. 250-260

Sebastien Coassolo, Nairie Michaelian, Timurs Maculins, Caleigh M. Azumaya, Tommy K. Cheung, Jianping Yin, Inna Zilberleyb, Kanika Bajaj Pahuja, Thomas Garner, Ted Lau, Davis Mau, Matthew Grimmer, Jean-Philippe Fortin, Mike Costa, Yoana N. Dimitrova, Christopher M. Rose, Peter L. Hsu and Robert L. Yauch

Mapping convergent regulators of melanoma drug resistance by PerturbFate pp. 261-271

Zihan Xu, Ziyu Lu, Aileen Ugurbil, Abdulraouf Abdulraouf, Andrew Liao, Jianxiang Zhang, Wei Zhou and Junyue Cao

Quadruple pegRNA enables programmable and efficient large genomic insertion pp. 272-281

Ya-jing Shi, Zi-yi Ding, Ying Wu, Zhou He, Yi-zhou Zhang, Yu-lu Zhang, Yu-ming Zhang, Xiang-rui Huang, Hao Yin and Ying Zhang

Science fiction: nine lab-life novels for your holiday reading pp. 283-285

Jeffrey M. Perkel, Anne Gulland, Jack Leeming, David Payne, Kendall Powell, Sophie McClarty, Alexia Austin and Mary Craig

‘Virtual cells’ aim to turn raw data into predictive models of biology pp. 286-288

Michael Eisenstein

Global plastics treaty must be built on a foundation of monitoring pp. 290-290

Chunhui Liu, Xiangang Hu, Karin Kvale and Li Mu

Power imbalances in adviser–student relationships need safeguarding pp. 290-290

Weiyu Qian

Is it time to ‘cap and trade’ credits for research-funding proposals? pp. 290-290

Neil M. Davies, David Bann, Matthew Keller and Marcus Munafò

Natural capital accounting needs a way to assess uncertainty pp. 290-290

Bálint Czúcz, Zander Venter and David N. Barton