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2025, volume 648, articles 8093

Darleane C. Hoffman obituary: chemist who expanded the periodic table pp. 270-270

Dawn Shaughnessy

2025, volume 648, articles 8092

Author Correction: Mechanisms of stretch-mediated skin expansion at single-cell resolution pp. E1-E1

Mariaceleste Aragona, Alejandro Sifrim, Milan Malfait, Yura Song, Jens Van Herck, Sophie Dekoninck, Souhir Gargouri, Gaëlle Lapouge, Benjamin Swedlund, Christine Dubois, Pieter Baatsen, Katlijn Vints, Seungmin Han, Fadel Tissir, Thierry Voet, Benjamin D. Simons and Cédric Blanpain

Growing cities face mounting challenges pp. S1-S1

Richard Hodson

Author Correction: Brahma safeguards canalization of cardiac mesoderm differentiation pp. E2-E2

Swetansu K. Hota, Kavitha S. Rao, Andrew P. Blair, Ali Khalilimeybodi, Kevin M. Hu, Reuben Thomas, Kevin So, Vasumathi Kameswaran, Jiewei Xu, Benjamin J. Polacco, Ravi V. Desai, Nilanjana Chatterjee, Austin Hsu, Jonathon M. Muncie, Aaron M. Blotnick, Sarah A. B. Winchester, Leor S. Weinberger, Ruth Hüttenhain, Irfan S. Kathiriya, Nevan J. Krogan, Jeffrey J. Saucerman and Benoit G. Bruneau

How cities can keep their cool pp. S2-S4

Michael Eisenstein

Author Correction: A metallic p-wave magnet with commensurate spin helix pp. E3-E3

Rinsuke Yamada, Max T. Birch, Priya R. Baral, Shun Okumura, Ryota Nakano, Shang Gao, Motohiko Ezawa, Takuya Nomoto, Jan Masell, Yuki Ishihara, Kamil K. Kolincio, Ilya Belopolski, Hajime Sagayama, Hironori Nakao, Kazuki Ohishi, Takashi Ohhara, Ryoji Kiyanagi, Taro Nakajima, Yoshinori Tokura, Taka-hisa Arima, Yukitoshi Motome, Moritz M. Hirschmann and Max Hirschberger

Author Correction: AIM2 in regulatory T cells restrains autoimmune diseases pp. E4-E4

Wei-Chun Chou, Zengli Guo, Hao Guo, Liang Chen, Ge Zhang, Kaixin Liang, Ling Xie, Xianming Tan, Sara A. Gibson, Elena Rampanelli, Yan Wang, Stephanie A. Montgomery, W. June Brickey, Meng Deng, Leslie Freeman, Song Zhang, Maureen A. Su, Xian Chen, Yisong Y. Wan and Jenny P.-Y. Ting

Great science happens in great teams — research assessments must try to capture that pp. 8-8

David Budtz Pedersen

Wooden skyscrapers point the way to more sustainable cities pp. S8-S10

Sedeer el-Showk

AI reviewers are here — we are not ready pp. 9-9

Giorgio F. Gilestro

Building mentally healthy cities with neuroscience pp. S11-S11

Simon Makin

What happened at COP30? 4 science take-homes from the climate summit pp. 11-13

Meghie Rodrigues and Jeff Tollefson

Cities aren’t built for women — it’s time to change that pp. S12-S12

Leslie Kern

Data drive city transportation forwards pp. S13-S15

Neil Savage

Cyberattacks’ harm to universities is growing — and so are their effects on research pp. 13-13

Diana Kwon

A brain implant that could rival Neuralink’s enters clinical trials pp. 14-15

Liam Drew

‘Anti-woke’ policies blamed for falling attendance at some US conferences pp. 15-16

Alexandra Witze

Geothermal networks let cities warm and cool as one pp. S16-S18

Peter Fairley

‘They don’t have symptoms’: CAR-T therapies send autoimmune diseases into remission pp. 16-17

Rachel Fieldhouse

Synthetic tongue rates chillies’ heat — and spares human tasters pp. 17-17

Jenna Ahart

We are all mosaics: vast genetic diversity found between cells in a single person pp. 18-18

Heidi Ledford

Will blockbuster obesity drugs revolutionize addiction treatment? pp. 20-22

Elie Dolgin

The ‘silent’ brain cells that shape our behaviour, memory and health pp. 23-25

Alison Abbott

Nature at its weirdest: what metamorphosis reveals about science and ourselves pp. 26-27

Itai Yanai

Spineless creatures, possibly the world’s oldest beer receipt and more: 2025’s best Books in brief pp. 28-30

Andrew Robinson

David Baltimore obituary: virologist whose enzyme discovery transformed understanding of cancer and HIV/AIDS pp. 31-31

Stephen Goff

A ten-year drive to credit authors for their work — and why there’s still more to do pp. 33-34

Liz Allen, Veronique Kiermer, Simon Porter and Ruth Whittam

Why universities need to radically rethink exams in the age of AI pp. 35-37

Vitomir Kovanović, Abhinava Barthakur, Srećko Joksimović and George Siemens

Alternatives to animal research are not inherently more ethical pp. 38-38

Michele A. Basso

Ease the EU postdoc job market with better routes to innovation pp. 38-38

Bram Servais

Drinking water is at risk during warfare — better protections are needed pp. 38-38

Rongsheng Ning, Yingying Xiang, Mauricius Marques dos Santos and Shane A. Snyder

Memes reveal threats to graduate-student mental health pp. 38-38

Samuel Paulo Cibulski

Fall-prevention clinical trial in rural China shows promising results pp. 39-40

Cynthia Swarnalatha and Sallie E. Lamb

Still no sign of hypothetical sterile-neutrino particle pp. 40-42

Patrick Huber

Even in space, telescopes can’t escape photobombers pp. 42-43

Meredith Rawls

Stop the nonsense: genome editing creates potentially therapeutic transfer RNAs pp. 43-45

Kim M. Keeling

Ethically sourced image data set encourages fairness in AI research pp. 45-46

Walter J. Scheirer

Pancreatic cancer relies on opposing signalling pathways to drive its cellular diversity pp. 46-48

Marc P. Stemmler

Quarks in ‘exotic’ quartets prefer to stick together pp. 48-49

Elena Santopinto

Taiwan invests in genetic resource for health pp. 49-50

Genevieve L. Wojcik

Satellite megaconstellations will threaten space-based astronomy pp. 51-57

Alejandro S. Borlaff, Pamela M. Marcum and Steve B. Howell

Glasses-free 3D display with ultrawide viewing range using deep learning pp. 76-83

Weijie Ma, Zhangrui Zhao, Canyu Zhao, Wanli Ouyang and Han-Sen Zhong

Tin-based perovskite solar cells with a homogeneous buried interface pp. 84-90

Tianpeng Li, Xin Luo, Peilin Wang, Zhi Li, Yimeng Li, Jinhai Huang, Zuoming Jin, Yingguo Yang, Bin Li, Wenqi Zhang, Siyuan Lin, Yichuan Rui, Hua Wang, Qinghong Zhang, Yiqiang Zhan, Bo Xu, Jia Liang and Yabing Qi

A matrix-confined molecular layer for perovskite photovoltaic modules pp. 91-96

Yugang Liang, Guodong Chen, Yao Wang, Yu Zou, Menglei Feng, Yanming Wang, Bowei Li, Yuljae Cho, Yide Chang, Tianle Liu, Taiyang Zhang, Yongbing Lou, Ranran Xu, Lei Lu, Ni Zhang, Ke Meng, Chen Zhu, Chuying Ouyang, Yanfeng Miao, Yongsheng Guo, Yuetian Chen and Yixin Zhao

Fair human-centric image dataset for ethical AI benchmarking pp. 97-108

Alice Xiang, Jerone T. A. Andrews, Rebecca L. Bourke, William Thong, Julienne M. LaChance, Tiffany Georgievski, Apostolos Modas, Aida Rahmattalabbi, Yunhao Ba, Shruti Nagpal, Orestis Papakyriakopoulos, Dora Zhao, Jinru Xue, Victoria Matthews, Linxia Gong, Austin T. Hoag, Mircea Cimpoi, Swami Sankaranarayanan, Wiebke Hutiri, Morgan K. Scheuerman, Albert S. Abedi, Peter Stone, Peter R. Wurman, Hiroaki Kitano and Michael Spranger

Co-option of an ancestral cloacal regulatory landscape during digit evolution pp. 109-116

Aurélie Hintermann, Christopher C. Bolt, M. Brent Hawkins, Guillaume Valentin, Lucille Lopez-Delisle, Madeline M. Ryan, Sandra Gitto, Paula Barrera Gómez, Bénédicte Mascrez, Thomas A. Mansour, Tetsuya Nakamura, Matthew P. Harris, Neil H. Shubin and Denis Duboule

The Taiwan Precision Medicine Initiative provides a cohort for large-scale studies pp. 117-127

Hsin-Chou Yang, Pui-Yan Kwok, Ling-Hui Li, Yi-Min Liu, Yuh-Jyh Jong, Kang-Yun Lee, Da-Wei Wang, Ming-Fang Tsai, Jenn-Hwai Yang, Chien-Hsiun Chen, Erh-Chan Yeh, Chun-yu Wei, Cathy S.-J. Fann, Yen-Tsung Huang, Chia-Wei Chen, Yi-Ju Lee, Shih-Kai Chu, Chih-hsing Ho, Cheng-Shin Yang, Yungling Leo Lee, Hung-Hsin Chen, Ming-Chih Hou, Jeng-Fong Chiou, Shun-Fa Yang, Chih-Hung Wang, Chih-Yang Huang, Kuan-Ming Chiu, Ming Chen, Fu-Tien Chiang, Sing-Lian Lee, Shiou-Sheng Chen, Wei-Jen Yao, Chih-Cheng Chien, Shih-Yao Lin, Fu-Pang Chang, Hsiang-Ling Ho, Yi-Chen Yeh, Wei-Cheng Tseng, Ming-Hwai Lin, Hsiao-Ting Chang, Ling-Ming Tseng, Wen-Yih Liang, Paul Chih-Hsueh Chen, Jen-Fan Hang, Shih-Chieh Lin, Yu-Jiun Chan, Ying-Ju Kuo, Lei-Chi Wang, Chin-Chen Pan, Yu-Cheng Hsieh, Yi-Ming Chen, Tzu-Hung Hsiao, Ching-Heng Lin, Yen-Ju Chen, I-Chieh Chen, Chien-Lin Mao, Shu-Jung Chang, Yen-Lin Chang, Yi-Ju Liao, Chih-Hung Lai, Wei-Ju Lee, Hsin Tung, Ting-Ting Yen, Hsin-Chien Yen, Chun-Ming Shih, Teh-Ying Chou, Tsan-Hon Liou, Chen-Yuan Chiang, Yih-Giun Cherng, Chih-Hwa Chen, Chao-Hua Chiu, Sung-Hui Tseng, Emily Pei-Ying Lin, Ying-Ju Chen, Hui-Ping Chuang, Tsai-Chuan Chen, Wei-Ting Huang, Joey Sin, I-Ling Liu, Yi-Chen Chen, Kuo-Kuang Chao, Yu-Min Wu, Pin-Pin Yu, Lung-Pao Chang, Kuei-Yao Yen, Li-Ching Chang, Yi-Jing Sheen, Yuan-Tsong Chen, Kamhon Kan, Hsiang-Lin Tsai, Yao-Kuang Wang, Ming-Feng Hou, Yuan-Han Yang, Chao-Hung Kuo, Wen-Jeng Wu, Jee-Fu Huang, Inn-Wen Chong, Jong-Rung Tsai, Cheng-Yu Lin, Ming-Chin Yu, Tsong-Hai Lee, Meng-Han Tsai, Yu-Che Ou, Pin-Yuan Chen, Tsung-Hui Hu, Yu-Chiau Shyu, Chih-Kuang Cheng, Yu-Jen Fang, Song-Chou Hsieh, Chien-Hung Chen, Chieh-Chang Chen, Ko-Jen Li, Chin-Hsien Lin, Hsien-Yi Chiu, Chen-Chi Wu, Chun-Yen Chen, Shi-Jye Chu, Feng-Cheng Liu, Fu-Chi Yang, Hsin-An Chang, Wei-liang Chen, Sung-Sen Yang, Yueh-feng Sung, Tso-Fu Wang, Shinn-Zong Lin, Yen-Wen Wu, Chien-Sheng Wu, Ju-Ying Jiang, Gwo-Chin Ma, Ting-Yu Chang, Juey-Jen Hwang, Kuo-Jang Kao, Chen-Fang Hung, Ting-Fang Chiu, Po-Yueh Chen, Kochung Tsui, Ming-Shiang Wu, See-Tong Pang, Shih-Ann Chen, Wei-Ming Chen, Chun-houh Chen, Wayne Huey-Herng Sheu and Jer-Yuarn Wu

Population-specific polygenic risk scores for people of Han Chinese ancestry pp. 128-137

Hung-Hsin Chen, Chien-Hsiun Chen, Ming-Chih Hou, Yun-Ching Fu, Ling-Hui Li, Che-Yu Chou, Erh-Chan Yeh, Ming-Fang Tsai, Chun-houh Chen, Hsin-Chou Yang, Yen-Tsung Huang, Yi-Min Liu, Chun-yu Wei, Jen-Ping Su, Wan-Jia Lin, Elin H. F. Wang, Chi-Lu Chiang, Jeng-Kai Jiang, I-Hui Lee, Kung-Hao Liang, Wei-Sheng Chen, Hung-Cheng Tsai, Shih-Yao Lin, Fu-Pang Chang, Hsiang-Ling Ho, Yi-Chen Yeh, Wei-Cheng Tseng, Ming-Hwai Lin, Hsiao-Ting Chang, Ling-Ming Tseng, Wen-Yih Liang, Paul Chih-Hsueh Chen, Yu-Cheng Hsieh, Yi-Ming Chen, Tzu-Hung Hsiao, Ching-Heng Lin, Yen-Ju Chen, I-Chieh Chen, Chien-Lin Mao, Shu-Jung Chang, Yen-Lin Chang, Yi-Ju Liao, Chih-Hung Lai, Wei-Ju Lee, Hsin Tung, Ting-Ting Yen, Hsin-Chien Yen, Ming-Yao Chen, Ying-Chin Lin, Yung-Ta Kao, Bi-Zhen Kao, Jing-Er Lee, Chi-Li Chung, Ju-Chi Liu, Paul Chan, Chang-Hsien Lin, Chia-Hsin Chen, I-Chen Wu, Lung-Chang Lin, Jiunn-Wei Wang, Shen-liang Shih, Sun-Wung Hsieh, Chih-Hsing Hung, Wei-Ming Li, Chih-Jen Yang, Cheng-Shin Yang, Ru-Hui Weng, Yu-Chi Chen, Chun-Ping Chang, Tai-Hsun Wu, Yu-Chang Lin, Yi-Jing Sheen, Shi-Heng Wang, Sye-Pu Chen, Timothy Raben, Erik Widen, Stephen Hsu, Feng-Jen Hsieh, Dong-Ru Ho, Yu-Huei Huang, Chung-Han Yang, Yu-Shu Huang, Yen-Fu Chen, Hsien-Ming Wu, Ping-Han Tsai, Kuan-Gen Huang, Chih-Yen Chien, Yi-Lwun Ho, Ming-Shiang Wu, Jia-Horng Kao, Yen-Bin Liu, Jyh-Ming Jimmy Juang, Mao-Hsin Lin, Yen-Hung Lin, Ji-Yuh Lee, Hsueh-Ju Lu, Chieh-Hua Lu, An-Chieh Feng, Jhih-Syuan Liu, Chien-Ping Chiang, Nain-Feng Chu, Jung-Chun Lin, Yi-Wei Yeh, En Meng, Chih-Yang Huang, Chi-Cheng Li, Tso-Fu Wang, Kuei-Ying Su, Jia-Kang Wang, Mei-Hsiu Chen, Hua-Fen Chen, Gwo-Chin Ma, Ting-Yu Chang, Fu-Tien Chiang, Hsing-Jung Chang, Kuo-Jang Kao, Chen-Fang Hung, Ching-Yao Tsai, Po-Yueh Chen, Kochung Tsui, Yuan-Tsong Chen, Pui-Yan Kwok, Wayne Huey-Herng Sheu, Shun-Fa Yang, Jyh-Ming Liou, Jaw-Yuan Wang, Jeng-Fong Chiou, Jer-Yuarn Wu and Cathy S. J. Fann

Integration of hunger and hormonal state gates infant-directed aggression pp. 138-145

Mingran Cao, Rachida Ammari, Maxwell X. Chen, Patty Wai, Bradley B. Jamieson, Swang Liang, Basma F. A. Husain, Aashna Sahni, Nathalie Legrave, Irene Salgarella, James MacRae, Molly Strom and Johannes Kohl

The astrocytic ensemble acts as a multiday trace to stabilize memory pp. 146-156

Ken-ichi Dewa, Kodai Kaseda, Aoi Kuwahara, Hideaki Kubotera, Ayato Yamasaki, Natsumi Awata, Atsuko Komori, Mika A. Holtz, Atsushi Kasai, Henrik Skibbe, Norio Takata, Tatsushi Yokoyama, Makoto Tsuda, Genri Numata, Shun Nakamura, Eiki Takimoto, Masayuki Sakamoto, Minako Ito, Takahiro Masuda and Jun Nagai

Lymphoid gene expression supports neuroprotective microglia function pp. 157-165

Pinar Ayata, Jessica M. Crowley, Matthew F. Challman, Vinaya Sahasrabuddhe, Maud Gratuze, Sebastian Werneburg, Diogo Ribeiro, Emma C. Hays, Violeta Durán-Laforet, Travis E. Faust, Philip Hwang, Francisco Mendes Lopes, Chrysa Nikopoulou, Sarah Buchholz, Robert E. Murphy, Taoyu Mei, Anna A. Pimenova, Carmen Romero-Molina, Francesca Garretti, Tulsi A. Patel, Claudia De Sanctis, Angie V. Ramirez Jimenez, Megan Crow, Felix D. Weiss, Jason D. Ulrich, Edoardo Marcora, John W. Murray, Felix Meissner, Andreas Beyer, Dan Hasson, John F. Crary, Dorothy P. Schafer, David M. Holtzman, Alison M. Goate, Alexander Tarakhovsky and Anne Schaefer

Enteropathogenic bacteria evade ROCK-driven epithelial cell extrusion pp. 166-172

Giovanni Luchetti, Marin V. Miner, Rachael M. Peterson, William P. Scott, Praveen Krishnamoorthy, Eric M. Kofoed, Angel G. Jimenez, Hua Zhang, Man Wah Tan, Rohit Reja, Tommy K. Cheung, Elizabeth Skippington, Yuxin Liang, Christopher M. Rose, Nobuhiko Kayagaki, Kim Newton, Isabella Rauch and Vishva M. Dixit

Niche-specific dermal macrophage loss promotes skin capillary ageing pp. 173-181

Kailin R. Mesa, Kevin A. O’Connor, Charles Ng, Steven P. Salvatore, Alexandra Dolynuk, Michelle Rivera Lomeli and Dan R. Littman

Spatial metabolic gradients in the liver and small intestine pp. 182-190

Laith Z. Samarah, Clover Zheng, Xi Xing, Won Dong Lee, Amichay Afriat, Uthsav Chitra, Michael R. MacArthur, Wenyun Lu, Connor S. R. Jankowski, Cong Ma, Craig J. Hunter, Michael Neinast, Daniel R. Weilandt, Benjamin J. Raphael and Joshua D. Rabinowitz

Prime editing-installed suppressor tRNAs for disease-agnostic genome editing pp. 191-202

Sarah E. Pierce, Steven Erwood, Keyede Oye, Meirui An, Nicholas Krasnow, Emily Zhang, Aditya Raguram, Davis Seelig, Mark J. Osborn and David R. Liu

SPP1 is required for maintaining mesenchymal cell fate in pancreatic cancer pp. 203-209

Huafu Li, Linxiang Lan, Hengxing Chen, May Zaw Thin, Hari Ps, Jessica K. Nelson, Ian M. Evans, E. Josue Ruiz, Rongjie Cheng, Li Tran, Mark Allen, Jian Ma, Tingzhuang Yi, Chunming Wang, Yulong He, Naomi Guppy, Anguraj Sadanandam, Shao-Zhen Lin, Changhua Zhang and Axel Behrens

KCTD10 is a sensor for co-directional transcription–replication conflicts pp. 210-219

Jake A. Kloeber, Bin Chen, Guangchao Sun, Charles S. King, Zhiquan Wang, Li Wang, Zheming Wu, Shouhai Zhu, Fei Zhao, Hongran Qin, Yaobin Ouyang, Huaping Xiao, Xinyi Tu, Jing Lu, Yanxia Jiang, Kuntian Luo, Ping Yin, Xinyan Wu, Robert W. Mutter, Jinzhou Huang and Zhenkun Lou

Mechanism of conductance control and neurosteroid binding in NMDA receptors pp. 220-228

Hyunook Kang, Ruben Steigerwald, Elijah Z. Ullman, Max Epstein, Srinu Paladugu, Dennis C. Liotta, Stephen F. Traynelis and Hiro Furukawa

Designing allosteric modulators to change GPCR G protein subtype selectivity pp. 229-238

Madelyn N. Moore, Kelsey L. Person, Valeria L. Robleto, Abigail R. Alwin, Campbell L. Krusemark, Noah Foster, Caroline Ray, Asuka Inoue, Michael R. Jackson, Michael J. Sheedlo, Lawrence S. Barak, Ezequiel Marron Fernandez de Velasco, Steven H. Olson and Lauren M. Slosky

Lessons from a long road to a first-author paper pp. 239-240

Poojashree Chettiar

Introducing the j-metric: a true measure of what matters in academia pp. 240-241

Dariusz Jemielniak

Climbing through the silver mine: my work as a geologist pp. 244-244

Dave Tacon