Nature

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2025, volume 640, articles 8057

‘Open source’ AI isn’t truly open — here’s how researchers can reclaim the term pp. 9-9

Stefano Maffulli

Superpowers want to control critical mineral supplies — local communities need a stronger say pp. 10-10

Rabah Arezki

How to get rid of toxic ‘forever chemical’ pollution pp. 22-24

XiaoZhi Lim

Style over substance? What birds’ mating behaviours reveal about sexual selection pp. 29-30

Tim Coulson

Six roadblocks to net zero — and how to get around them pp. 31-34

Lucas Joppa and Elizabeth Willmott

The full lethal impact of massive cuts to international food aid pp. 35-37

Saskia Osendarp, Marie Ruel, Emorn Udomkesmalee, Masresha Tessema and Lawrence Haddad

The global scientific community must keep studying LGBT+ health pp. 38-38

Cláudia C. Gonçalves, Lana J. Williams, Alison R. Yung and Ashleigh Lin

Action needed to mitigate effects of slashing USAID pp. 38-38

Zaheer Allam and Ali Cheshmehzangi

Minerals will shape future geopolitical order pp. 38-38

Mariusz Baranowski, Piotr Jabkowski and Daniel M. Kammen

China has already taken steps to reduce retractions of papers from its hospitals pp. 38-38

Gong Jie Zhang and Ya Bin Zhou

How the Atlantic jet stream has changed in 600 years — and what it means for weather pp. 39-40

Matthew P. Dannenberg and Erika K. Wise

The early origins of bone-tool manufacturing traditions by hominins 1.5 million years ago pp. 40-42

Marta Mirazón Lahr

Genus-wide plant pangenome could inform next-generation crop design pp. 44-45

Nadia Kamal and Manuel Spannagl

Designer cannabinoids could be the key to pain relief without adverse effects pp. 45-46

Iain R. Greig and Ruth A. Ross

How to know whether a conference is right for you pp. 275-277

Christine Ro

Deep dive: How I use robots to survey coral reefs pp. 280-280

Nikki Forrester

2025, volume 639, articles 8056

Author Correction: Warming and cooling catalyse widespread temporal turnover in biodiversity pp. E20-E20

Malin L. Pinsky, Helmut Hillebrand, Jonathan M. Chase, Laura H. Antão, Myriam R. Hirt, Ulrich Brose, Michael T. Burrows, Benoit Gauzens, Benjamin Rosenbaum and Shane A. Blowes

Author Correction: Transforming a head direction signal into a goal-oriented steering command pp. E21-E21

Elena A. Westeinde, Emily Kellogg, Paul M. Dawson, Jenny Lu, Lydia Hamburg, Benjamin Midler, Shaul Druckmann and Rachel I. Wilson

Author Correction: Classification with a disordered dopant atom network in silicon pp. E22-E22

Tao Chen, Jeroen van Gelder, Bram van de Ven, Sergey V. Amitonov, Bram de Wilde, Hans-Christian Ruiz Euler, Hajo Broersma, Peter A. Bobbert, Floris A. Zwanenburg and Wilfred G. van der Wiel

Author Correction: Observation of Nagaoka polarons in a Fermi–Hubbard quantum simulator pp. E23-E23

Martin Lebrat, Muqing Xu, Lev Haldar Kendrick, Anant Kale, Youqi Gang, Pranav Seetharaman, Ivan Morera, Ehsan Khatami, Eugene Demler and Markus Greiner

Climate change will send home insurance spiralling. Here’s how to control costs pp. 839-839

Scott St. George

Empower families to lead the design of their ageing loved ones’ health care pp. 840-840

Shahmir H. Ali

Light pollution threatens fleet of world-class telescopes in Atacama Desert pp. 843-844

Humberto Basilio

NIH has cut one mRNA-vaccine grant. Will more follow? pp. 844-845

Max Kozlov

Measles is surging in the US: how bad could it get? pp. 846-847

Julian Nowogrodzki

Catchy, clear, concise: three-part phrases boost research paper citations pp. 847-848

Dalmeet Singh Chawla

Man survives with titanium heart for 100 days — a world first pp. 848-849

Smriti Mallapaty

Is dark energy getting weaker? Fresh data bolster shock finding pp. 849-849

Davide Castelvecchi

Immune cells ‘bandage’ wounds with bacteria-trapping goo pp. 850-850

Miryam Naddaf

AI is transforming peer review — and many scientists are worried pp. 852-854

Miryam Naddaf

Fasting for weight loss is all the rage: what are the health benefits? pp. 855-857

Nic Fleming

The expanding Universe — do ongoing tensions leave room for new physics? pp. 858-860

Wendy Freedman

Glaciers are not just blocks of ice — plans to save them mustn’t overlook their hidden life pp. 861-863

Tom J. Battin, Albert van Wijngaarden, Birgit Sattler, Alexandre M. Anesio, Joseph Cook, Matthias Huss and Arwyn Edwards

Microbes can capture carbon and degrade plastic — why aren’t we using them more? pp. 864-866

Rino Rappuoli, Nguyen K. Nguyen, David E. Bloom, Charles Brooke, Rachel M. Burckhardt, Alan D. Dangour, Dilfuza Egamberdieva, Gigi K. Gronvall, Trevor D. Lawley, Jay T. Lennon, Ryan Morhard, Aindrila Mukhopadhyay, Raquel Peixoto, Pamela A. Silver and Lisa Y. Stein

How to get more women into mining pp. 867-867

Linqi Huang, Xibing Li, Longjun Dong and Haoxuan Yu

Give grants to female scientists in war zones pp. 867-867

Natalia Tsybuliak and Yana Suchikova

Lesotho matters pp. 867-867

Nthabiseng Mokoena-Mokhali, Liteboho Senyane, Brian Stewart and Peter Mitchell

Lessons from Portugal on effects of cutting research funding pp. 867-867

Marc Veldhoen, João T. Barata, Luisa M. Figueiredo and Claus M. Azzalin

Evolutionary flexibility to gain or lose tooth complexity sparks fish diversification pp. 869-870

Nare Ngoepe

A lighthouse galaxy shines unexpectedly through the fog of the cosmic dawn pp. 870-872

Michele Trenti

Protein waste turned into antibiotics as a defence strategy of human cells pp. 872-873

Tim Clausen

Nursing-home residents’ skin is a source of transmitted harmful and drug-resistant microbes pp. 873-875

Teresa R. O’Meara

Fossilized dinosaur cells that defied the ravages of time — 20 years since a key discovery pp. 875-876

Jasmina Wiemann

The other climate crisis pp. 877-887

Tiffany A. Shaw and Bjorn Stevens

Multimodal generative AI for medical image interpretation pp. 888-896

Vishwanatha M. Rao, Michael Hla, Michael Moor, Subathra Adithan, Stephen Kwak, Eric J. Topol and Pranav Rajpurkar

Witnessing the onset of reionization through Lyman-α emission at redshift 13 pp. 897-901

Joris Witstok, Peter Jakobsen, Roberto Maiolino, Jakob M. Helton, Benjamin D. Johnson, Brant E. Robertson, Sandro Tacchella, Alex J. Cameron, Renske Smit, Andrew J. Bunker, Aayush Saxena, Fengwu Sun, Stacey Alberts, Santiago Arribas, William M. Baker, Rachana Bhatawdekar, Kristan Boyett, Phillip A. Cargile, Stefano Carniani, Stéphane Charlot, Jacopo Chevallard, Mirko Curti, Emma Curtis-Lake, Francesco D’Eugenio, Daniel J. Eisenstein, Kevin N. Hainline, Gareth C. Jones, Nimisha Kumari, Michael V. Maseda, Pablo G. Pérez-González, Pierluigi Rinaldi, Jan Scholtz, Hannah Übler, Christina C. Williams, Christopher N. A. Willmer, Chris Willott and Yongda Zhu

Vertical structure of an exoplanet’s atmospheric jet stream pp. 902-908

Julia V. Seidel, Bibiana Prinoth, Lorenzo Pino, Leonardo A. Santos, Hritam Chakraborty, Vivien Parmentier, Elyar Sedaghati, Joost P. Wardenier, Casper Farret Jentink, Maria Rosa Zapatero Osorio, Romain Allart, David Ehrenreich, Monika Lendl, Giulia Roccetti, Yuri Damasceno, Vincent Bourrier, Jorge Lillo-Box, H. Jens Hoeijmakers, Enric Pallé, Nuno Santos, Alejandro Suárez Mascareño, Sergio G. Sousa, Hugo M. Tabernero and Francesco A. Pepe

Electroluminescence and energy transfer mediated by hyperbolic polaritons pp. 909-914

Loubnan Abou-Hamdan, Aurélien Schmitt, Rémi Bretel, Sylvio Rossetti, Marin Tharrault, David Mele, Aurélie Pierret, Michael Rosticher, Takashi Taniguchi, Kenji Watanabe, Camille Maestre, Catherine Journet, Bérangère Toury, Vincent Garnier, Philippe Steyer, James H. Edgar, Eli Janzen, Jean-Marc Berroir, Gwendal Fève, Gerbold Ménard, Bernard Plaçais, Christophe Voisin, Jean-Paul Hugonin, Elise Bailly, Benjamin Vest, Jean-Jacques Greffet, Patrick Bouchon, Yannick De Wilde and Emmanuel Baudin

Hyperbolic phonon-polariton electroluminescence in 2D heterostructures pp. 915-921

Qiushi Guo, Iliya Esin, Cheng Li, Chen Chen, Guanyu Han, Song Liu, James H. Edgar, Selina Zhou, Eugene Demler, Gil Refael and Fengnian Xia

Down-converted photon pairs in a high-Q silicon nitride microresonator pp. 922-927

Bohan Li, Zhiquan Yuan, James Williams, Warren Jin, Adrian Beckert, Tian Xie, Joel Guo, Avi Feshali, Mario Paniccia, Andrei Faraon, John Bowers, Alireza Marandi and Kerry Vahala

An ultra-broadband photonic-chip-based parametric amplifier pp. 928-934

Nikolai Kuznetsov, Alberto Nardi, Johann Riemensberger, Alisa Davydova, Mikhail Churaev, Paul Seidler and Tobias J. Kippenberg

Adaptive locomotion of active solids pp. 935-941

Jonas Veenstra, Colin Scheibner, Martin Brandenbourger, Jack Binysh, Anton Souslov, Vincenzo Vitelli and Corentin Coulais

Record sea surface temperature jump in 2023–2024 unlikely but not unexpected pp. 942-946

Jens Terhaar, Friedrich A. Burger, Linus Vogt, Thomas L. Frölicher and Thomas F. Stocker

Sliding and healing of frictional interfaces that appear stationary pp. 947-953

Krittanon Sirorattanakul, Stacy Larochelle, Vito Rubino, Nadia Lapusta and Ares J. Rosakis

Vulnerability of amphibians to global warming pp. 954-961

Patrice Pottier, Michael R. Kearney, Nicholas C. Wu, Alex R. Gunderson, Julie E. Rej, A. Nayelli Rivera-Villanueva, Pietro Pollo, Samantha Burke, Szymon M. Drobniak and Shinichi Nakagawa

Evolutionary lability of a key innovation spurs rapid diversification pp. 962-967

Nick Peoples, Michael D. Burns, Michalis Mihalitsis and Peter C. Wainwright

Genomics yields biological and phenotypic insights into bipolar disorder pp. 968-975

Kevin S. O’Connell, Maria Koromina, Tracey van der Veen, Toni Boltz, Friederike S. David, Jessica Mei Kay Yang, Keng-Han Lin, Xin Wang, Jonathan R. I. Coleman, Brittany L. Mitchell, Caroline C. McGrouther, Aaditya V. Rangan, Penelope A. Lind, Elise Koch, Arvid Harder, Nadine Parker, Jaroslav Bendl, Kristina Adorjan, Esben Agerbo, Diego Albani, Silvia Alemany, Ney Alliey-Rodriguez, Thomas D. Als, Till F. M. Andlauer, Anastasia Antoniou, Helga Ask, Nicholas Bass, Michael Bauer, Eva C. Beins, Tim B. Bigdeli, Carsten Bøcker Pedersen, Marco P. Boks, Sigrid Børte, Rosa Bosch, Murielle Brum, Ben M. Brumpton, Nathalie Brunkhorst-Kanaan, Monika Budde, Jonas Bybjerg-Grauholm, William Byerley, Judit Cabana-Domínguez, Murray J. Cairns, Bernardo Carpiniello, Miquel Casas, Pablo Cervantes, Chris Chatzinakos, Hsi-Chung Chen, Tereza Clarence, Toni-Kim Clarke, Isabelle Claus, Brandon Coombes, Elizabeth C. Corfield, Cristiana Cruceanu, Alfredo Cuellar-Barboza, Piotr M. Czerski, Konstantinos Dafnas, Anders M. Dale, Nina Dalkner, Franziska Degenhardt, J. Raymond DePaulo, Srdjan Djurovic, Ole Kristian Drange, Valentina Escott-Price, Ayman H. Fanous, Frederike T. Fellendorf, I. Nicol Ferrier, Liz Forty, Josef Frank, Oleksandr Frei, Nelson B. Freimer, John F. Fullard, Julie Garnham, Ian R. Gizer, Scott D. Gordon, Katherine Gordon-Smith, Tiffany A. Greenwood, Jakob Grove, José Guzman-Parra, Tae Hyon Ha, Tim Hahn, Magnus Haraldsson, Martin Hautzinger, Alexandra Havdahl, Urs Heilbronner, Dennis Hellgren, Stefan Herms, Ian B. Hickie, Per Hoffmann, Peter A. Holmans, Ming-Chyi Huang, Masashi Ikeda, Stéphane Jamain, Jessica S. Johnson, Lina Jonsson, Janos L. Kalman, Yoichiro Kamatani, James L. Kennedy, Euitae Kim, Jaeyoung Kim, Sarah Kittel-Schneider, James A. Knowles, Manolis Kogevinas, Thorsten M. Kranz, Kristi Krebs, Steven A. Kushner, Catharina Lavebratt, Jacob Lawrence, Markus Leber, Heon-Jeong Lee, Calwing Liao, Susanne Lucae, Martin Lundberg, Donald J. MacIntyre, Wolfgang Maier, Adam X. Maihofer, Dolores Malaspina, Mirko Manchia, Eirini Maratou, Lina Martinsson, Manuel Mattheisen, Nathaniel W. McGregor, Melvin G. McInnis, James D. McKay, Helena Medeiros, Andreas Meyer-Lindenberg, Vincent Millischer, Derek W. Morris, Paraskevi Moutsatsou, Thomas W. Mühleisen, Claire O’Donovan, Catherine M. Olsen, Georgia Panagiotaropoulou, Sergi Papiol, Antonio F. Pardiñas, Hye Youn Park, Amy Perry, Andrea Pfennig, Claudia Pisanu, James B. Potash, Digby Quested, Mark H. Rapaport, Eline J. Regeer, John P. Rice, Margarita Rivera, Eva C. Schulte, Fanny Senner, Alexey Shadrin, Paul D. Shilling, Engilbert Sigurdsson, Lisa Sindermann, Lea Sirignano, Dan Siskind, Claire Slaney, Laura G. Sloofman, Olav B. Smeland, Daniel J. Smith, Janet L. Sobell, Maria Soler Artigas, Dan J. Stein, Frederike Stein, Mei-Hsin Su, Heejong Sung, Beata Świątkowska, Chikashi Terao, Markos Tesfaye, Martin Tesli, Thorgeir E. Thorgeirsson, Jackson G. Thorp, Claudio Toma, Leonardo Tondo, Paul A. Tooney, Shih-Jen Tsai, Evangelia Eirini Tsermpini, Marquis P. Vawter, Helmut Vedder, Annabel Vreeker, James T. R. Walters, Bendik S. Winsvold, Stephanie H. Witt, Hong-Hee Won, Robert Ye, Allan H. Young, Peter P. Zandi, Lea Zillich, Rolf Adolfsson, Martin Alda, Lars Alfredsson, Lena Backlund, Bernhard T. Baune, Frank Bellivier, Susanne Bengesser, Wade H. Berrettini, Joanna M. Biernacka, Michael Boehnke, Anders D. Børglum, Gerome Breen, Vaughan J. Carr, Stanley Catts, Sven Cichon, Aiden Corvin, Nicholas Craddock, Udo Dannlowski, Dimitris Dikeos, Bruno Etain, Panagiotis Ferentinos, Mark Frye, Janice M. Fullerton, Micha Gawlik, Elliot S. Gershon, Fernando S. Goes, Melissa J. Green, Maria Grigoroiu-Serbanescu, Joanna Hauser, Frans A. Henskens, Jens Hjerling-Leffler, David M. Hougaard, Kristian Hveem, Nakao Iwata, Ian Jones, Lisa A. Jones, René S. Kahn, John R. Kelsoe, Tilo Kircher, George Kirov, Po-Hsiu Kuo, Mikael Landén, Marion Leboyer, Qingqin S. Li, Jolanta Lissowska, Christine Lochner, Carmel Loughland, Jurjen J. Luykx, Nicholas G. Martin, Carol A. Mathews, Fermin Mayoral, Susan L. McElroy, Andrew M. McIntosh, Francis J. McMahon, Sarah E. Medland, Ingrid Melle, Lili Milani, Philip B. Mitchell, Gunnar Morken, Ole Mors, Preben Bo Mortensen, Bertram Müller-Myhsok, Richard M. Myers, Woojae Myung, Benjamin M. Neale, Caroline M. Nievergelt, Merete Nordentoft, Markus M. Nöthen, John I. Nurnberger, Michael C. O’Donovan, Ketil J. Oedegaard, Tomas Olsson, Michael J. Owen, Sara A. Paciga, Christos Pantelis, Carlos N. Pato, Michele T. Pato, George P. Patrinos, Joanna M. Pawlak, Josep Antoni Ramos-Quiroga, Andreas Reif, Eva Z. Reininghaus, Marta Ribasés, Marcella Rietschel, Stephan Ripke, Guy A. Rouleau, Panos Roussos, Takeo Saito, Ulrich Schall, Martin Schalling, Peter R. Schofield, Thomas G. Schulze, Laura J. Scott, Rodney J. Scott, Alessandro Serretti, Jordan W. Smoller, Alessio Squassina, Eli A. Stahl, Hreinn Stefansson, Kari Stefansson, Eystein Stordal, Fabian Streit, Patrick F. Sullivan, Gustavo Turecki, Arne E. Vaaler, Eduard Vieta, John B. Vincent, Irwin D. Waldman, Cynthia S. Weickert, Thomas W. Weickert, Thomas Werge, David C. Whiteman, John-Anker Zwart, Howard J. Edenberg, Andrew McQuillin, Andreas J. Forstner, Niamh Mullins, Arianna Di Florio, Roel A. Ophoff and Ole A. Andreassen

Measuring racial educational disparities over time amongst top achievers pp. 976-984

Uditi Karna, Min Sok Lee, John A. List, Andrew Simon and Haruka Uchida

Glycocalyx dysregulation impairs blood–brain barrier in ageing and disease pp. 985-994

Sophia M. Shi, Ryan J. Suh, D. Judy Shon, Francisco J. Garcia, Josephine K. Buff, Micaiah Atkins, Lulin Li, Nannan Lu, Bryan Sun, Jian Luo, Ning-Sum To, Tom H. Cheung, M. Windy McNerney, Myriam Heiman, Carolyn R. Bertozzi and Tony Wyss-Coray

Left–right-alternating theta sweeps in entorhinal–hippocampal maps of space pp. 995-1005

Abraham Z. Vollan, Richard J. Gardner, May-Britt Moser and Edvard I. Moser

A crucial role for the cortical amygdala in shaping social encounters pp. 1006-1015

Antonio V. Aubry, Romain Durand- de Cuttoli, Elizabeth Karpman, Rachel L. Fisher-Foye, Lyonna F. Parise, Flurin Cathomas, C. Joseph Burnett, Yewon Yang, Chongzhen Yuan, Alexa R. LaBanca, Kenny L. Chan, Kion T. Winston, Hsiao-yun Lin, Farah Dackour, Arman A. Tavallaei, Johana Alvarez, Tadaaki Nishioka, Hirofumi Morishita, Robert C. Froemke, Long Li and Scott J. Russo

Clonal Candida auris and ESKAPE pathogens on the skin of residents of nursing homes pp. 1016-1023

Diana M. Proctor, Sarah E. Sansom, Clay Deming, Sean Conlan, Ryan A. Blaustein, Thomas K. Atkins, Thelma Dangana, Christine Fukuda, Lahari Thotapalli, Heidi H. Kong, Michael Y. Lin, Mary K. Hayden and Julia A. Segre

Differential protection against SARS-CoV-2 reinfection pre- and post-Omicron pp. 1024-1031

Hiam Chemaitelly, Houssein H. Ayoub, Peter Coyle, Patrick Tang, Mohammad R. Hasan, Hadi M. Yassine, Asmaa A. Al Thani, Zaina Al-Kanaani, Einas Al-Kuwari, Andrew Jeremijenko, Anvar Hassan Kaleeckal, Ali Nizar Latif, Riyazuddin Mohammad Shaik, Hanan F. Abdul-Rahim, Gheyath K. Nasrallah, Mohamed Ghaith Al-Kuwari, Adeel A. Butt, Hamad Eid Al-Romaihi, Mohamed H. Al-Thani, Abdullatif Al-Khal, Roberto Bertollini and Laith J. Abu-Raddad

Cell-autonomous innate immunity by proteasome-derived defence peptides pp. 1032-1041

Karin Goldberg, Arseniy Lobov, Paola Antonello, Merav D. Shmueli, Idan Yakir, Tal Weizman, Adi Ulman, Daoud Sheban, Einav Laser, Matthias P. Kramer, Ronen Shteinvil, Guoyun Chen, Angham Ibraheem, Vera Sysoeva, Vered Fishbain-Yoskovitz, Gayatree Mohapatra, Anat Abramov, Sandy Shimshi, Kseniia Ogneva, Madhurima Nandy, Sivan Amidror, Hadar Bootz-Maoz, Shanny H. Kuo, Nili Dezorella, Assaf Kacen, Aaron Javitt, Gee W. Lau, Nissan Yissachar, Zvi Hayouka and Yifat Merbl

RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer pp. 1042-1051

Zachary Sethna, Pablo Guasp, Charlotte Reiche, Martina Milighetti, Nicholas Ceglia, Erin Patterson, Jayon Lihm, George Payne, Olga Lyudovyk, Luis A. Rojas, Nan Pang, Akihiro Ohmoto, Masataka Amisaki, Abderezak Zebboudj, Zagaa Odgerel, Emmanuel M. Bruno, Siqi Linsey Zhang, Charlotte Cheng, Yuval Elhanati, Evelyna Derhovanessian, Luisa Manning, Felicitas Müller, Ina Rhee, Mahesh Yadav, Taha Merghoub, Jedd D. Wolchok, Olca Basturk, Mithat Gönen, Andrew S. Epstein, Parisa Momtaz, Wungki Park, Ryan Sugarman, Anna M. Varghese, Elizabeth Won, Avni Desai, Alice C. Wei, Michael I. D’Angelica, T. Peter Kingham, Kevin C. Soares, William R. Jarnagin, Jeffrey Drebin, Eileen M. O’Reilly, Ira Mellman, Ugur Sahin, Özlem Türeci, Benjamin D. Greenbaum and Vinod P. Balachandran

Clonal driver neoantigen loss under EGFR TKI and immune selection pressures pp. 1052-1059

Maise Al Bakir, James L. Reading, Samuel Gamble, Rachel Rosenthal, Imran Uddin, Andrew Rowan, Joanna Przewrocka, Amber Rogers, Yien Ning Sophia Wong, Amalie K. Bentzen, Selvaraju Veeriah, Sophia Ward, Aaron T. Garnett, Paula Kalavakur, Carlos Martínez-Ruiz, Clare Puttick, Ariana Huebner, Daniel E. Cook, David A. Moore, Chris Abbosh, Crispin T. Hiley, Cristina Naceur-Lombardelli, Thomas B. K. Watkins, Marina Petkovic, Roland F. Schwarz, Felipe Gálvez-Cancino, Kevin Litchfield, Peter Meldgaard, Boe Sandahl Sorensen, Line Bille Madsen, Dirk Jäger, Martin D. Forster, Tobias Arkenau, Clara Domingo-Vila, Timothy I. M. Tree, Mohammad Kadivar, Sine Reker Hadrup, Benny Chain, Sergio A. Quezada, Nicholas McGranahan and Charles Swanton

GABAergic neuron-to-glioma synapses in diffuse midline gliomas pp. 1060-1068

Tara Barron, Belgin Yalçın, Minhui Su, Youkyeong Gloria Byun, Avishai Gavish, Kiarash Shamardani, Haojun Xu, Lijun Ni, Neeraj Soni, Vilina Mehta, Samin Maleki Jahan, Yoon Seok Kim, Kathryn R. Taylor, Michael B. Keough, Michael A. Quezada, Anna C. Geraghty, Rebecca Mancusi, Linh Thuy Vo, Enrique Herrera Castañeda, Pamelyn J. Woo, Claudia K. Petritsch, Hannes Vogel, Kai Kaila and Michelle Monje

Plasmodium blood stage development requires the chromatin remodeller Snf2L pp. 1069-1075

Maria Theresia Watzlowik, Elisabeth Silberhorn, Sujaan Das, Ritwik Singhal, Kannan Venugopal, Simon Holzinger, Barbara Stokes, Ella Schadt, Lauriane Sollelis, Victoria A. Bonnell, Matthew Gow, Andreas Klingl, Matthias Marti, Manuel Llinás, Markus Meissner and Gernot Längst

A metagenomic ‘dark matter’ enzyme catalyses oxidative cellulose conversion pp. 1076-1083

Clelton A. Santos, Mariana A. B. Morais, Fernanda Mandelli, Evandro A. Lima, Renan Y. Miyamoto, Paula M. R. Higasi, Evandro A. Araujo, Douglas A. A. Paixão, Joaquim M. Junior, Maria L. Motta, Rodrigo S. A. Streit, Luana G. Morão, Claudio B. C. Silva, Lucia D. Wolf, Cesar R. F. Terrasan, Nathalia R. Bulka, Jose A. Diogo, Felipe J. Fuzita, Felippe M. Colombari, Camila R. Santos, Priscila T. Rodrigues, Daiane B. Silva, Sacha Grisel, Juliana S. Bernardes, Nicolas Terrapon, Vincent Lombard, Antonio J. C. Filho, Bernard Henrissat, Bastien Bissaro, Jean-Guy Berrin, Gabriela F. Persinoti and Mario T. Murakami

Mechanism for local attenuation of DNA replication at double-strand breaks pp. 1084-1092

Robin Sebastian, Eric G. Sun, Michael Fedkenheuer, Haiqing Fu, SeolKyoung Jung, Bhushan L. Thakur, Christophe E. Redon, Gianluca Pegoraro, Andy D. Tran, Jacob M. Gross, Sara Mosavarpour, Nana Afua Kusi, Anagh Ray, Anjali Dhall, Lorinc S. Pongor, Rafael Casellas and Mirit I. Aladjem

Structure and mechanism of the Zorya anti-phage defence system pp. 1093-1101

Haidai Hu, Philipp F. Popp, Thomas C. D. Hughes, Aritz Roa-Eguiara, Nicole R. Rutbeek, Freddie J. O. Martin, Ivo Alexander Hendriks, Leighton J. Payne, Yumeng Yan, Dorentina Humolli, Victor Klein-Sousa, Inga Songailiene, Yong Wang, Michael Lund Nielsen, Richard M. Berry, Alexander Harms, Marc Erhardt, Simon A. Jackson and Nicholas M. I. Taylor

Shaking up earthquake safety in Nepal with a folk song pp. 1103-1105

Saugat Bolakhe

RNA function follows form – why is it so hard to predict? pp. 1106-1108

Diana Kwon

Reviving the biodiversity around an ancient palace pp. 1110-1110

Ugo Mellone

2025, volume 639, articles 8055

Trump’s return puts renewables at a crossroads pp. S17-S17

Simon Baker

How the US tech industry is shaping the transition to green energy pp. S18-S21

Mark Peplow

Battery researchers strive for standardization pp. S25-S27

Katharine Sanderson

What is stopping a complete switch to clean energy? pp. S30-S31

Benjamin Plackett

Meeting the energy challenge posed by data centres is central to a green future pp. S33-S33

Dasom Lee

Governments must stop hoarding climate data pp. 547-547

Santiago Beguería

Don’t wait out four hard years: speak truth to power pp. 548-548

Arthur Caplan

‘Scientists will not be silenced’: thousands protest Trump research cuts pp. 551-552

Julian Nowogrodzki, Humberto Basilio, Heidi Ledford, Brendan Maher and Alexandra Witze

Move over graphene! Scientists forge bismuthene and host of atoms-thick metals pp. 553-553

Katherine Bourzac

How the NIH dominates the world’s health research — in charts pp. 554-555

Nisha Gaind

Microsoft quantum computing ‘breakthrough’ faces fresh challenge pp. 555-556

Dan Garisto

How a PhD student’s lab size affects their chance of future academic success pp. 556-557

Humberto Basilio

How fast your brain ages is affected by these 64 genes pp. 557-558

Miryam Naddaf

NASA begins mass firings of scientists ahead of Trump team’s deadline pp. 558-558

Alexandra Witze

The biggest machine in science: inside the fight to build the next giant particle collider pp. 560-563

Davide Castelvecchi

Swarms of satellites are harming astronomy. Here’s how researchers are fighting back pp. 564-566

Alexandra Witze

A radical manifesto for truth pp. 567-569

Julia P. G. Jones

The untamed river and the Moog: Books in brief pp. 569-569

Andrew Robinson

Elisabeth Vrba obituary: palaeontologist who solved a problem that vexed Darwin pp. 570-570

Niles Eldredge

Space debris is falling from the skies. We need to tackle this growing danger pp. 571-573

Richard O. Ocaya and Thembinkosi D. Malevu

Why coalitions of wealthy nations should fund others to decarbonize pp. 574-576

Patrick Bolton, Ottmar Edenhofer, Alissa Kleinnijenhuis, Johan Rockström and Jeromin Zettelmeyer

Japan needs a fresh approach to innovation pp. 577-577

Peter Gruss

Global cooperation is crucial for DeepSeek and broader AI research pp. 577-577

Haoyu Liu

AI demands a different approach to education pp. 577-577

Ziqiang Zeng and Jiuping Xu

US disruptions to science could transform global research landscape pp. 577-577

Chunyu Zhang and Liping Liu

Fish gills and human ears share the same genetic blueprint pp. 579-580

Ruiqi Liu and Maksim V. Plikus

Ancient peat reveals that sea level surged rapidly twice at the end of the last ice age pp. 580-582

Nicole S. Khan

Putting the brakes on mitochondrial fusion to prevent escape of mitochondrial DNA pp. 582-584

Kate McArthur and Michael T. Ryan

Errors in the Huntington’s disease gene accumulate slowly and then all at once pp. 584-586

Veera M. Rajagopal and Sahar Gelfman

Key process in sex-cell formation can finally be studied in vitro pp. 586-587

Francisco Mendez Diaz and Kevin D. Corbett

Long-term studies provide unique insights into evolution pp. 589-601

James T. Stroud and William C. Ratcliff

Disorder-assisted real–momentum topological photonic crystal pp. 602-608

Haoye Qin, Zengping Su, Zhe Zhang, Wenjing Lv, Zijin Yang, Weijin Chen, Xinyue Gao, Heng Wei, Yuzhi Shi, Bo Li, Ji Zhou, Romain Fleury, Cheng-Wei Qiu and Qinghua Song

Optimizing generative AI by backpropagating language model feedback pp. 609-616

Mert Yuksekgonul, Federico Bianchi, Joseph Boen, Sheng Liu, Pan Lu, Zhi Huang, Carlos Guestrin and James Zou

A mixed-precision memristor and SRAM compute-in-memory AI processor pp. 617-623

Win-San Khwa, Tai-Hao Wen, Hung-Hsi Hsu, Wei-Hsing Huang, Yu-Chen Chang, Ting-Chien Chiu, Zhao-En Ke, Yu-Hsiang Chin, Hua-Jin Wen, Wei-Ting Hsu, Chung-Chuan Lo, Ren-Shuo Liu, Chih-Cheng Hsieh, Kea-Tiong Tang, Mon-Shu Ho, Ashwin Sanjay Lele, Shih-Hsin Teng, Chung-Cheng Chou, Yu- Der Chih, Tsung-Yung Jonathan Chang and Meng-Fan Chang

A generative model for inorganic materials design pp. 624-632

Claudio Zeni, Robert Pinsler, Daniel Zügner, Andrew Fowler, Matthew Horton, Xiang Fu, Zilong Wang, Aliaksandra Shysheya, Jonathan Crabbé, Shoko Ueda, Roberto Sordillo, Lixin Sun, Jake Smith, Bichlien Nguyen, Hannes Schulz, Sarah Lewis, Chin-Wei Huang, Ziheng Lu, Yichi Zhou, Han Yang, Hongxia Hao, Jielan Li, Chunlei Yang, Wenjie Li, Ryota Tomioka and Tian Xie

Homogeneous ZnSeTeS quantum dots for efficient and stable pure-blue LEDs pp. 633-638

Qianqian Wu, Fan Cao, Wenke Yu, Sheng Wang, Wenjun Hou, Zizhe Lu, Weiran Cao, Jiaqi Zhang, Xiaoyu Zhang, Yingguo Yang, Guohua Jia, Jianhua Zhang and Xuyong Yang

Large recoverable elastic energy in chiral metamaterials via twist buckling pp. 639-645

Xin Fang, Dianlong Yu, Jihong Wen, Yifan Dai, Matthew R. Begley, Huajian Gao and Peter Gumbsch

Fingerprinting the recovery of Antarctic ozone pp. 646-651

Peidong Wang, Susan Solomon, Benjamin D. Santer, Douglas E. Kinnison, Qiang Fu, Kane A. Stone, Jun Zhang, Gloria L. Manney and Luis F. Millán

Global sea-level rise in the early Holocene revealed from North Sea peats pp. 652-657

Marc P. Hijma, Sarah L. Bradley, Kim M. Cohen, Wouter Wal, Natasha L. M. Barlow, Bas Blank, Manfred Frechen, Rick Hennekam, Sytze Heteren, Patrick Kiden, Antonis Mavritsakis, Bart M. L. Meijninger, Gert-Jan Reichart, Lutz Reinhardt, Kenneth F. Rijsdijk, Annemiek Vink and Freek S. Busschers

High temporal variability not trend dominates Mediterranean precipitation pp. 658-666

Sergio M. Vicente-Serrano, Yves Tramblay, Fergus Reig, José C. González-Hidalgo, Santiago Beguería, Michele Brunetti, Ksenija Cindrić Kalin, Leonardo Patalen, Aleksandra Kržič, Piero Lionello, Miguel M. Lima, Ricardo M. Trigo, Ahmed M. El-Kenawy, Ali Eddenjal, Murat Türkes, Aristeidis Koutroulis, Veronica Manara, Maurizio Maugeri, Wafae Badi, Shifa Mathbout, Renato Bertalanič, Lilia Bocheva, Ismail Dabanli, Alexandru Dumitrescu, Brigitte Dubuisson, Salah Sahabi-Abed, Fayez Abdulla, Abbas Fayad, Sabina Hodzic, Mirjana Ivanov, Ivan Radevski, Dhais Peña-Angulo, Jorge Lorenzo-Lacruz, Fernando Domínguez-Castro, Luis Gimeno-Sotelo, Ricardo García-Herrera, Magí Franquesa, Amar Halifa-Marín, Maria Adell-Michavila, Ivan Noguera, David Barriopedro, Jose M. Garrido-Perez, Cesar Azorin-Molina, Miguel Andres-Martin, Luis Gimeno, Raquel Nieto, Maria Carmen Llasat, Yannis Markonis, Rabeb Selmi, Soumaya Rached, Slavica Radovanović, Jean-Michel Soubeyroux, Aurélien Ribes, Mohamed Elmehdi Saidi, Siham Bataineh, El Mahdi El Khalki, Sayed Robaa, Amina Boucetta, Karam Alsafadi, Nikos Mamassis, Safwan Mohammed, Beatriz Fernández-Duque, Sorin Cheval, Sara Moutia, Aleksandra Stevkov, Silvana Stevkova, M. Yolanda Luna and Vera Potopová

Increasing hourly heavy rainfall in Austria reflected in flood changes pp. 667-672

Klaus Haslinger, Korbinian Breinl, Lovrenc Pavlin, Georg Pistotnik, Miriam Bertola, Marc Olefs, Marion Greilinger, Wolfgang Schöner and Günter Blöschl

Children’s arithmetic skills do not transfer between applied and academic mathematics pp. 673-681

Abhijit V. Banerjee, Swati Bhattacharjee, Raghabendra Chattopadhyay, Esther Duflo, Alejandro J. Ganimian, Kailash Rajah and Elizabeth S. Spelke

Repurposing of a gill gene regulatory program for outer-ear evolution pp. 682-690

Mathi Thiruppathy, Lauren Teubner, Ryan R. Roberts, Micaela C. Lasser, Alessandra Moscatello, Ya-Wen Chen, Christian Hochstim, Seth Ruffins, Arijita Sarkar, Jade Tassey, Denis Evseenko, Thomas P. Lozito, Helen Rankin Willsey, J. Andrew Gillis and J. Gage Crump

Genome duplication in a long-term multicellularity evolution experiment pp. 691-699

Kai Tong, Sayantan Datta, Vivian Cheng, Daniella J. Haas, Saranya Gourisetti, Harley L. Yopp, Thomas C. Day, Dung T. Lac, Ahmad S. Khalil, Peter L. Conlin, G. Ozan Bozdag and William C. Ratcliff

Complete human recombination maps pp. 700-707

Gunnar Palsson, Marteinn T. Hardarson, Hakon Jonsson, Valgerdur Steinthorsdottir, Olafur A. Stefansson, Hannes P. Eggertsson, Sigurjon A. Gudjonsson, Pall I. Olason, Arnaldur Gylfason, Gisli Masson, Unnur Thorsteinsdottir, Patrick Sulem, Agnar Helgason, Daniel F. Gudbjartsson, Bjarni V. Halldorsson and Kari Stefansson

A comprehensive spatio-cellular map of the human hypothalamus pp. 708-716

John A. Tadross, Lukas Steuernagel, Georgina K. C. Dowsett, Katherine A. Kentistou, Sofia Lundh, Marta Porniece, Paul Klemm, Kara Rainbow, Henning Hvid, Katarzyna Kania, Joseph Polex-Wolf, Lotte Bjerre Knudsen, Charles Pyke, John R. B. Perry, Brian Y. H. Lam, Jens C. Brüning and Giles S. H. Yeo

An opponent striatal circuit for distributional reinforcement learning pp. 717-726

Adam S. Lowet, Qiao Zheng, Melissa Meng, Sara Matias, Jan Drugowitsch and Naoshige Uchida

CARD domains mediate anti-phage defence in bacterial gasdermin systems pp. 727-734

Tanita Wein, Adi Millman, Katharina Lange, Erez Yirmiya, Romi Hadary, Jeremy Garb, Sarah Melamed, Gil Amitai, Orly Dym, Felix Steinruecke, Aidan B. Hill, Philip J. Kranzusch and Rotem Sorek

Precise modelling of mitochondrial diseases using optimized mitoBEs pp. 735-745

Xiaoxue Zhang, Xue Zhang, Jiwu Ren, Jiayi Li, Xiaoxu Wei, Ying Yu, Zongyi Yi and Wensheng Wei

IL-27 elicits a cytotoxic CD8+ T cell program to enforce tumour control pp. 746-753

Béatrice Bréart, Katherine Williams, Stellanie Krimm, Tiffany Wong, Brandon D. Kayser, Lifen Wang, Eric Cheng, Mayra Cruz Tleugabulova, Romain Bouziat, Tianshi Lu, Kobe Yuen, Natalie S. Firmino, Daniel D. Bravo, Juliette Roels, Atish Bhakta, Jack Bevers, Isabelle Lehoux, Alan Gutierrez, Yajun Chestnut, Joanna E. Klementowicz, Teresita L. Arenzana, Ilseyar Akhmetzyanova, Elizabeth Dixon, Min Chen, Kazi Tasneem, Rajbharan Yadav, Hartmut Koeppen, Soyoung A. Oh, Lélia Delamarre, Haochu Huang, Shion A. Lim, Gerald Nakamura, Jianyong Wang, Chan Gao, Racquel Corpuz, Sören Müller and Nathaniel R. West

Human-correlated genetic models identify precision therapy for liver cancer pp. 754-764

Miryam Müller, Stephanie May, Holly Hall, Timothy J. Kendall, Lynn McGarry, Lauriane Blukacz, Sandro Nuciforo, Anastasia Georgakopoulou, Thomas Jamieson, Narisa Phinichkusolchit, Sandeep Dhayade, Toshiyasu Suzuki, Júlia Huguet-Pradell, Ian R. Powley, Leah Officer-Jones, Rachel L. Pennie, Roger Esteban-Fabró, Albert Gris-Oliver, Roser Pinyol, George L. Skalka, Jack Leslie, Matthew Hoare, Joep Sprangers, Gaurav Malviya, Agata Mackintosh, Emma Johnson, Misti McCain, John Halpin, Christos Kiourtis, Colin Nixon, Graeme Clark, William Clark, Robin Shaw, Ann Hedley, Thomas M. Drake, Ee Hong Tan, Matt Neilson, Daniel J. Murphy, David Y. Lewis, Helen L. Reeves, John Quesne, Derek A. Mann, Leo M. Carlin, Karen Blyth, Josep M. Llovet, Markus H. Heim, Owen J. Sansom, Crispin J. Miller and Thomas G. Bird

Intrinsic electrical activity drives small-cell lung cancer progression pp. 765-775

Paola Peinado, Marco Stazi, Claudio Ballabio, Michael-Bogdan Margineanu, Zhaoqi Li, Caterina I. Colón, Min-Shu Hsieh, Shreoshi Pal Choudhuri, Victor Stastny, Seth Hamilton, Alix Le Marois, Jodie Collingridge, Linus Conrad, Yinxing Chen, Sheng Rong Ng, Margaret Magendantz, Arjun Bhutkar, Jin-Shing Chen, Erik Sahai, Benjamin J. Drapkin, Tyler Jacks, Matthew G. Vander Heiden, Maksym V. Kopanitsa, Hugh P. C. Robinson and Leanne Li

Dual regulation of mitochondrial fusion by Parkin–PINK1 and OMA1 pp. 776-783

Tatsuya Yamada, Arisa Ikeda, Daisuke Murata, Hu Wang, Cissy Zhang, Pratik Khare, Yoshihiro Adachi, Fumiya Ito, Pedro M. Quirós, Seth Blackshaw, Carlos López-Otín, Thomas Langer, David C. Chan, Anne Le, Valina L. Dawson, Ted M. Dawson, Miho Iijima and Hiromi Sesaki

Reconstitution of SPO11-dependent double-strand break formation pp. 784-791

Zhi Zheng, Lyuqin Zheng, Meret Arter, Kaixian Liu, Shintaro Yamada, David Ontoso, Soonjoung Kim and Scott Keeney

SPO11 dimers are sufficient to catalyse DNA double-strand breaks in vitro pp. 792-799

Cédric Oger and Corentin Claeys Bouuaert

In vitro reconstitution of meiotic DNA double-strand-break formation pp. 800-807

Xinzhe Tang, Zetao Hu, Jian Ding, Meixia Wu, Pin Guan, Yawei Song, Yue Yin, Wei Wu, Jinbiao Ma, Ying Huang and Ming-Han Tong

Structure and mechanism of vitamin-K-dependent γ-glutamyl carboxylase pp. 808-815

Rong Wang, Baozhi Chen, Nadia Elghobashi-Meinhardt, Jian-Ke Tie, Alyssa Ayala, Ning Zhou and Xiaofeng Qi

Molecular basis of vitamin-K-driven γ-carboxylation at the membrane interface pp. 816-824

Qing Cao, Aaron Ammerman, Mierxiati Saimi, Zongtao Lin, Guomin Shen, Huaping Chen, Jie Sun, Mengqi Chai, Shixuan Liu, Fong-Fu Hsu, Andrzej M. Krezel, Michael L. Gross, Jinbin Xu, Benjamin A. Garcia, Bin Liu and Weikai Li

How researchers can work fairly with Indigenous and local knowledge pp. 825-827

Oscar Allan

How I connect Colombia’s remote communities to safer water pp. 830-830

Esme Hedley

2025, volume 639, articles 8054

Weather anomalies cannot explain insect decline pp. E7-E11

Caspar A. Hallmann, Eelke Jongejans, Thomas Hörren, Martin Sorg, Henk Siepel, Roland Mühlethaler, Gerlind U. C. Lehmann and Hans Kroon

Reply to: Weather anomalies cannot explain insect decline pp. E12-E13

Jörg Müller, Torsten Hothorn, Ye Yuan, Sebastian Seibold, Oliver Mitesser, Julia Rothacher, Julia Freund, Clara Wild, Marina Wolz and Annette Menzel

Author Correction: The genetic origin of the Indo-Europeans pp. E14-E14

Iosif Lazaridis, Nick Patterson, David Anthony, Leonid Vyazov, Romain Fournier, Harald Ringbauer, Iñigo Olalde, Alexander A. Khokhlov, Egor P. Kitov, Natalia I. Shishlina, Sorin C. Ailincăi, Danila S. Agapov, Sergey A. Agapov, Elena Batieva, Baitanayev Bauyrzhan, Zsolt Bereczki, Alexandra Buzhilova, Piya Changmai, Andrey A. Chizhevsky, Ion Ciobanu, Mihai Constantinescu, Marietta Csányi, János Dani, Peter K. Dashkovskiy, Sándor Évinger, Anatoly Faifert, Pavel Flegontov, Alin Frînculeasa, Mădălina N. Frînculeasa, Tamás Hajdu, Tom Higham, Paweł Jarosz, Pavol Jelínek, Valeri I. Khartanovich, Eduard N. Kirginekov, Viktória Kiss, Alexandera Kitova, Alexeiy V. Kiyashko, Jovan Koledin, Arkady Korolev, Pavel Kosintsev, Gabriella Kulcsár, Pavel Kuznetsov, Rabadan Magomedov, Aslan M. Mamedov, Eszter Melis, Vyacheslav Moiseyev, Erika Molnár, Janet Monge, Octav Negrea, Nadezhda A. Nikolaeva, Mario Novak, Maria Ochir-Goryaeva, György Pálfi, Sergiu Popovici, Marina P. Rykun, Tatyana M. Savenkova, Vladimir P. Semibratov, Nikolai N. Seregin, Alena Šefčáková, Raikhan S. Mussayeva, Irina Shingiray, Vladimir N. Shirokov, Angela Simalcsik, Kendra Sirak, Konstantin N. Solodovnikov, Judit Tárnoki, Alexey A. Tishkin, Viktor Trifonov, Sergey Vasilyev, Ali Akbari, Esther S. Brielle, Kim Callan, Francesca Candilio, Olivia Cheronet, Elizabeth Curtis, Olga Flegontova, Lora Iliev, Aisling Kearns, Denise Keating, Ann Marie Lawson, Matthew Mah, Adam Micco, Megan Michel, Jonas Oppenheimer, Lijun Qiu, J. Noah Workman, Fatma Zalzala, Anna Szécsényi-Nagy, Pier Francesco Palamara, Swapan Mallick, Nadin Rohland, Ron Pinhasi and David Reich

Author Correction: HIV-1 Env trimers asymmetrically engage CD4 receptors in membranes pp. E15-E15

Wenwei Li, Zhuan Qin, Elizabeth Nand, Michael W. Grunst, Jonathan R. Grover, Julian W. Bess, Jeffrey D. Lifson, Michael B. Zwick, Hemant D. Tagare, Pradeep D. Uchil and Walther Mothes

Author Correction: The Ronne Ice Shelf survived the last interglacial pp. E16-E16

Eric W. Wolff, Robert Mulvaney, Mackenzie M. Grieman, Helene M. Hoffmann, Jack Humby, Christoph Nehrbass-Ahles, Rachael H. Rhodes, Isobel F. Rowell, Louise C. Sime, Hubertus Fischer, Thomas F. Stocker, Amaelle Landais, Frédéric Parrenin, Eric J. Steig, Marina Dütsch and Nicholas R. Golledge

Author Correction: A comprehensive spatio-cellular map of the human hypothalamus pp. E17-E17

John A. Tadross, Lukas Steuernagel, Georgina K. C. Dowsett, Katherine A. Kentistou, Sofia Lundh, Marta Porniece, Paul Klemm, Kara Rainbow, Henning Hvid, Katarzyna Kania, Joseph Polex-Wolf, Lotte Bjerre Knudsen, Charles Pyke, John R. B. Perry, Brian Y. H. Lam, Jens C. Brüning and Giles S. H. Yeo

Author Correction: Neutralizing GDF-15 can overcome anti-PD-1 and anti-PD-L1 resistance in solid tumours pp. E18-E18

Ignacio Melero, Maria Miguel Luken, Guillermo Velasco, Elena Garralda, Juan Martín-Liberal, Markus Joerger, Guzman Alonso, Maria-Elisabeth Goebeler, Martin Schuler, David König, Reinhard Dummer, Maria Reig, Maria-Esperanza Rodriguez Ruiz, Emiliano Calvo, Jorge Esteban-Villarrubia, Arjun Oberoi, Paula Sabat, Juan José Soto-Castillo, Kira-Lee Koster, Omar Saavedra, Cyrus Sayehli, Tanja Gromke, Heinz Läubli, Egle Ramelyte, Marta Fortuny, Ana Landa-Magdalena, Irene Moreno, Javier Torres-Jiménez, Alberto Hernando-Calvo, Dagmar Hess, Fabricio Racca, Heike Richly, Andreas M. Schmitt, Corinne Eggenschwiler, Marco Sanduzzi-Zamparelli, Anna Vilalta-Lacarra, Jörg Trojan, Christine Koch, Peter R. Galle, Friedrich Foerster, Zlatko Trajanoski, Hubert Hackl, Falk Gogolla, Florestan J. Koll, Peter Wild, Felix Kyoung Hwan Chun, Henning Reis, Peter Lloyd, Matthias Machacek, Thomas F. Gajewski, Wolf H. Fridman, Alexander M. M. Eggermont, Ralf Bargou, Sandra Schöniger, Josef Rüschoff, Anastasiia Tereshchenko, Carina Zink, Antonio Silva, Felix S. Lichtenegger, Julia Akdemir, Manfred Rüdiger, Phil L’Huillier, Aradhana Dutta, Markus Haake, Alexandra Auckenthaler, Ana Gjorgjioska, Bernhard Rössler, Frank Hermann, Mara Liebig, Daniela Reichhardt, Christine Schuberth-Wagner, Jörg Wischhusen, Petra Fettes, Marlene Auer, Kathrin Klar and Eugen Leo

Author Correction: CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors pp. E19-E19

Ferdinandos Skoulidis, Haniel A. Araujo, Minh Truong Do, Yu Qian, Xin Sun, Ana Galan Cobo, John T. Le, Meagan Montesion, Rachael Palmer, Nadine Jahchan, Joseph M. Juan, Chengyin Min, Yi Yu, Xuewen Pan, Kathryn C. Arbour, Natalie Vokes, Stephanie T. Schmidt, David Molkentine, Dwight H. Owen, Regan Memmott, Pradnya D. Patil, Melina E. Marmarelis, Mark M. Awad, Joseph C. Murray, Jessica A. Hellyer, Justin F. Gainor, Anastasios Dimou, Christine M. Bestvina, Catherine A. Shu, Jonathan W. Riess, Collin M. Blakely, Chad V. Pecot, Laura Mezquita, Fabrizio Tabbó, Matthias Scheffler, Subba Digumarthy, Meghan J. Mooradian, Adrian G. Sacher, Sally C. M. Lau, Andreas N. Saltos, Julia Rotow, Rocio Perez Johnson, Corinne Liu, Tyler Stewart, Sarah B. Goldberg, Jonathan Killam, Zenta Walther, Kurt Schalper, Kurtis D. Davies, Mark G. Woodcock, Valsamo Anagnostou, Kristen A. Marrone, Patrick M. Forde, Biagio Ricciuti, Deepti Venkatraman, Eliezer M. Allen, Amy L. Cummings, Jonathan W. Goldman, Hiram Shaish, Melanie Kier, Sharyn Katz, Charu Aggarwal, Ying Ni, Joseph T. Azok, Jeremy Segal, Lauren Ritterhouse, Joel W. Neal, Ludovic Lacroix, Yasir Y. Elamin, Marcelo V. Negrao, Xiuning Le, Vincent K. Lam, Whitney E. Lewis, Haley N. Kemp, Brett Carter, Jack A. Roth, Stephen Swisher, Richard Lee, Teng Zhou, Alissa Poteete, Yifan Kong, Tomohiro Takehara, Alvaro Guimaraes Paula, Edwin R. Parra Cuentas, Carmen Behrens, Ignacio I. Wistuba, Jianjun Zhang, George R. Blumenschein, Carl Gay, Lauren A. Byers, Don L. Gibbons, Anne Tsao, J. Jack Lee, Trever G. Bivona, D. Ross Camidge, Jhannelle E. Gray, Natasha B. Leighl, Benjamin Levy, Julie R. Brahmer, Marina C. Garassino, David R. Gandara, Edward B. Garon, Naiyer A. Rizvi, Giorgio Vittorio Scagliotti, Jürgen Wolf, David Planchard, Benjamin Besse, Roy S. Herbst, Heather A. Wakelee, Nathan A. Pennell, Alice T. Shaw, Pasi A. Jänne, David P. Carbone, Matthew D. Hellmann, Charles M. Rudin, Lee Albacker, Helen Mann, Zhou Zhu, Zhongwu Lai, Ross Stewart, Solange Peters, Melissa L. Johnson, Kwok K. Wong, Alan Huang, Monte M. Winslow, Michael J. Rosen, Ian P. Winters, Vassiliki A. Papadimitrakopoulou, Tina Cascone, Philip Jewsbury and John V. Heymach

‘Silence is complicity’ — universities must fight the anti-DEI crackdown pp. 277-277

Rebecca Calisi Rodríguez

Public-health experts should be more political, not less pp. 278-278

Eric Reinhart

Exclusive: NIH to terminate hundreds of active research grants pp. 281-282

Max Kozlov and Smriti Mallapaty

Trump’s nominee for NIH chief talks frozen grants and fostering ‘scientific dissent’ pp. 282-283

Julian Nowogrodzki

Meet the ‘woolly mouse’: why scientists doubt it’s a big step towards recreating mammoths pp. 284-285

Ewen Callaway

China’s supreme court calls for crack down on paper mills pp. 285-286

Smriti Mallapaty

Why women’s brains are more resilient: it could be their ‘silent’ X chromosome pp. 286-287

Katherine Bourzac

Private spacecraft nails Moon landing: first images of Blue Ghost on the lunar surface pp. 287-288

Alexandra Witze

‘Omg, did PubMed go dark?’ Blackout stokes fears about database’s future pp. 288-288

Smriti Mallapaty

Alcohol and cancer risk: what you need to know pp. 290-292

Helen Pearson

Four ways COVID changed virology: lessons from the most sequenced virus of all time pp. 293-295

Ewen Callaway

The ‘quantum’ principle that says why atoms are as they are pp. 296-299

Olival Freire and Thiago Hartz

Rock hunters, tree huggers and taxi drivers: Books in brief pp. 299-299

Andrew Robinson

Are microplastics bad for your health? More rigorous science is needed pp. 300-302

Jun-Li Xu, Stephanie Wright, Cassandra Rauert and Kevin V. Thomas

How a vast digital twin of the Yangtze River could prevent flooding in China pp. 303-305

Xiaopeng Wang, Biqiong Wu, Guoliang Zhou, Tao Wang, Fanwei Meng, Li Zhou, Hui Cao and Zhengyang Tang

Fate of pistachio production in Iran holds lessons for the world pp. 306-306

Mostafa Farajpour

COP30 must deliver binding mechanisms to address climate change, not empty promises pp. 306-306

Stephannie Fernandes and Pranay Ranjan

For more reliable AI, academics should edit Wikipedia pp. 306-306

Declan Finney and Tatjana Baleta

Similar chiral phenomena occur in cell cultures and human crowds pp. 306-306

Anandwardhan A. Hardikar, Ramesh R. Bhonde, Malati R. Umrani and Mugdha V. Joglekar

Genetic data from Indigenous Greenlanders could help to narrow health-care gap pp. 307-309

Laura Arbour

Metals squeezed to thickness of just two atoms pp. 309-310

Javier Sanchez-Yamagishi

Racial bias eliminated when ratings switch from five stars to thumbs up or down pp. 310-311

Lauren Rivera

An operating system for networked quantum computers is a huge practical step forward pp. 312-313

Claudio Cicconetti

Peptides from abnormal RNA processing in cancer offer an immunotherapy target pp. 313-314

Al Charest

A framework for neural organoids, assembloids and transplantation studies pp. 315-320

Sergiu P. Pașca, Paola Arlotta, Helen S. Bateup, J. Gray Camp, Silvia Cappello, Fred H. Gage, Jürgen A. Knoblich, Arnold R. Kriegstein, Madeline A. Lancaster, Guo-Li Ming, Gaia Novarino, Hideyuki Okano, Malin Parmar, In-Hyun Park, Orly Reiner, Hongjun Song, Lorenz Studer, Jun Takahashi, Sally Temple, Giuseppe Testa, Barbara Treutlein, Flora M. Vaccarino, Pierre Vanderhaeghen and Tracy Young-Pearse

An operating system for executing applications on quantum network nodes pp. 321-328

C. Delle Donne, M. Iuliano, B. Vecht, G. M. Ferreira, H. Jirovská, T. J. W. Steenhoven, A. Dahlberg, M. Skrzypczyk, D. Fioretto, M. Teller, P. Filippov, A. R.-P. Montblanch, J. Fischer, H. B. Ommen, N. Demetriou, D. Leichtle, L. Music, H. Ollivier, I. Raa, W. Kozlowski, T. H. Taminiau, P. Pawełczak, T. E. Northup, R. Hanson and S. Wehner

Continuous-variable multipartite entanglement in an integrated microcomb pp. 329-336

Xinyu Jia, Chonghao Zhai, Xuezhi Zhu, Chang You, Yunyun Cao, Xuguang Zhang, Yun Zheng, Zhaorong Fu, Jun Mao, Tianxiang Dai, Lin Chang, Xiaolong Su, Qihuang Gong and Jianwei Wang

Emerging supersolidity in photonic-crystal polariton condensates pp. 337-341

Dimitrios Trypogeorgos, Antonio Gianfrate, Manuele Landini, Davide Nigro, Dario Gerace, Iacopo Carusotto, Fabrizio Riminucci, Kirk W. Baldwin, Loren N. Pfeiffer, Giovanni I. Martone, Milena Giorgi, Dario Ballarini and Daniele Sanvitto

Superconductivity and quantized anomalous Hall effect in rhombohedral graphene pp. 342-347

Youngjoon Choi, Ysun Choi, Marco Valentini, Caitlin L. Patterson, Ludwig F. W. Holleis, Owen I. Sheekey, Hari Stoyanov, Xiang Cheng, Takashi Taniguchi, Kenji Watanabe and Andrea F. Young

Magnetically and optically active edges in phosphorene nanoribbons pp. 348-353

Arjun Ashoka, Adam J. Clancy, Naitik A. Panjwani, Adam Cronin, Loren Picco, Eva S. Y. Aw, Nicholas J. M. Popiel, Alexander G. Eaton, Thomas G. Parton, Rebecca R. C. Shutt, Sascha Feldmann, Remington Carey, Thomas J. Macdonald, Cheng Liu, Marion E. Severijnen, Sandra Kleuskens, Loreta A. Muscarella, Felix R. Fischer, Hilton Barbosa de Aguiar, Richard H. Friend, Jan Behrends, Peter C. M. Christianen, Christopher A. Howard and Raj Pandya

Realization of 2D metals at the ångström thickness limit pp. 354-359

Jiaojiao Zhao, Lu Li, Peixuan Li, Liyan Dai, Jingwei Dong, Lanying Zhou, Yizhe Wang, Peihang Zhang, Kunshan Ji, Yangkun Zhang, Hua Yu, Zheng Wei, Jiawei Li, Xiuzhen Li, Zhiheng Huang, Boxin Wang, Jieying Liu, Yutong Chen, Xingchao Zhang, Shuopei Wang, Na Li, Wei Yang, Dongxia Shi, Jinbo Pan, Shixuan Du, Luojun Du and Guangyu Zhang

10,000-h-stable intermittent alkaline seawater electrolysis pp. 360-367

Qihao Sha, Shiyuan Wang, Li Yan, Yisui Feng, Zhuang Zhang, Shihang Li, Xinlong Guo, Tianshui Li, Hui Li, Zhongbin Zhuang, Daojin Zhou, Bin Liu and Xiaoming Sun

Methane oxidation to ethanol by a molecular junction photocatalyst pp. 368-374

Jijia Xie, Cong Fu, Matthew G. Quesne, Jian Guo, Chao Wang, Lunqiao Xiong, Christopher D. Windle, Srinivas Gadipelli, Zheng Xiao Guo, Weixin Huang, C. Richard A. Catlow and Junwang Tang

Engineered enzymes for enantioselective nucleophilic aromatic substitutions pp. 375-381

Thomas M. Lister, George W. Roberts, Euan J. Hossack, Fei Zhao, Ashleigh J. Burke, Linus O. Johannissen, Florence J. Hardy, Alexander A. V. Millman, David Leys, Igor Larrosa and Anthony P. Green

Global biodiversity loss from outsourced deforestation pp. 389-394

R. Alex Wiebe and David S. Wilcove

Scale dichotomization reduces customer racial discrimination and income inequality pp. 395-403

Tristan L. Botelho, Sora Jun, Demetrius Humes and Katherine A. DeCelles

Genetic architecture in Greenland is shaped by demography, structure and selection pp. 404-410

Frederik Filip Stæger, Mette K. Andersen, Zilong Li, Jasmin Pernille Hjerresen, Shixu He, Cindy G. Santander, Rasmus Tanderup Jensen, Karsten Fleischer Rex, Anne Cathrine Baun Thuesen, Kristian Hanghøj, Inge Høst Seiding, Emil Jørsboe, Sara Elizabeth Stinson, Malthe Sebro Rasmussen, Renzo F. Balboa, Christina Viskum Lytken Larsen, Peter Bjerregaard, Mikkel Schubert, Jonas Meisner, Allan Linneberg, Niels Grarup, Eleftheria Zeggini, Rasmus Nielsen, Marit E. Jørgensen, Torben Hansen, Ida Moltke and Anders Albrechtsen

Massively parallel characterization of transcriptional regulatory elements pp. 411-420

Vikram Agarwal, Fumitaka Inoue, Max Schubach, Dmitry Penzar, Beth K. Martin, Pyaree Mohan Dash, Pia Keukeleire, Zicong Zhang, Ajuni Sohota, Jingjing Zhao, Ilias Georgakopoulos-Soares, William S. Noble, Galip Gürkan Yardımcı, Ivan V. Kulakovskiy, Martin Kircher, Jay Shendure and Nadav Ahituv

Individual variability of neural computations underlying flexible decisions pp. 421-429

Marino Pagan, Vincent D. Tang, Mikio C. Aoi, Jonathan W. Pillow, Valerio Mante, David Sussillo and Carlos D. Brody

Experience-dependent dopamine modulation of male aggression pp. 430-437

Bing Dai, Bingqin Zheng, Xiuzhi Dai, Xiaoyang Cui, Luping Yin, Jing Cai, Yizhou Zhuo, Nicolas X. Tritsch, Larry S. Zweifel, Yulong Li and Dayu Lin

Activation and inhibition mechanisms of a plant helper NLR pp. 438-446

Yinyan Xiao, Xiaoxian Wu, Zaiqing Wang, Kexin Ji, Yang Zhao, Yu Zhang and Li Wan

Balanced plant helper NLR activation by a modified host protein complex pp. 447-455

Shijia Huang, Junli Wang, Ridan Song, Aolin Jia, Yu Xiao, Yue Sun, Lin Wang, Dennis Mahr, Zhongshou Wu, Zhifu Han, Xin Li, Jane E. Parker and Jijie Chai

Multi-interface licensing of protein import into a phage nucleus pp. 456-462

Claire Kokontis, Timothy A. Klein, Sukrit Silas and Joseph Bondy-Denomy

Tumour-wide RNA splicing aberrations generate actionable public neoantigens pp. 463-473

Darwin W. Kwok, Nicholas O. Stevers, Iñaki Etxeberria, Takahide Nejo, Maggie Colton Cove, Lee H. Chen, Jangham Jung, Kaori Okada, Senthilnath Lakshmanachetty, Marco Gallus, Abhilash Barpanda, Chibo Hong, Gary K. L. Chan, Jerry Liu, Samuel H. Wu, Emilio Ramos, Akane Yamamichi, Payal B. Watchmaker, Hirokazu Ogino, Atsuro Saijo, Aidan Du, Nadia R. Grishanina, James Woo, Aaron Diaz, Shawn L. Hervey-Jumper, Susan M. Chang, Joanna J. Phillips, Arun P. Wiita, Christopher A. Klebanoff, Joseph F. Costello and Hideho Okada

A neoantigen vaccine generates antitumour immunity in renal cell carcinoma pp. 474-482

David A. Braun, Giorgia Moranzoni, Vipheaviny Chea, Bradley A. McGregor, Eryn Blass, Chloe R. Tu, Allison P. Vanasse, Cleo Forman, Juliet Forman, Alexander B. Afeyan, Nicholas R. Schindler, Yiwen Liu, Shuqiang Li, Jackson Southard, Steven L. Chang, Michelle S. Hirsch, Nicole R. LeBoeuf, Oriol Olive, Ambica Mehndiratta, Haley Greenslade, Keerthi Shetty, Susan Klaeger, Siranush Sarkizova, Christina B. Pedersen, Matthew Mossanen, Isabel Carulli, Anna Tarren, Joseph Duke-Cohan, Alexis A. Howard, J. Bryan Iorgulescu, Bohoon Shim, Jeremy M. Simon, Sabina Signoretti, Jon C. Aster, Liudmila Elagina, Steven A. Carr, Ignaty Leshchiner, Gad Getz, Stacey Gabriel, Nir Hacohen, Lars R. Olsen, Giacomo Oliveira, Donna S. Neuberg, Kenneth J. Livak, Sachet A. Shukla, Edward F. Fritsch, Catherine J. Wu, Derin B. Keskin, Patrick A. Ott and Toni K. Choueiri

Tissue-resident memory CD8 T cell diversity is spatiotemporally imprinted pp. 483-492

Miguel Reina-Campos, Alexander Monell, Amir Ferry, Vida Luna, Kitty P. Cheung, Giovanni Galletti, Nicole E. Scharping, Kennidy K. Takehara, Sara Quon, Peter P. Challita, Brigid Boland, Yun Hsuan Lin, William H. Wong, Cynthia S. Indralingam, Hayley Neadeau, Suzie Alarcón, Gene W. Yeo, John T. Chang, Maximilian Heeg and Ananda W. Goldrath

Transcriptional adaptation upregulates utrophin in Duchenne muscular dystrophy pp. 493-502

Lara Falcucci, Christopher M. Dooley, Douglas Adamoski, Thomas Juan, Justin Martinez, Angelina M. Georgieva, Kamel Mamchaoui, Cansu Cirzi and Didier Y. R. Stainier

Engineered heart muscle allografts for heart repair in primates and humans pp. 503-511

Ahmad-Fawad Jebran, Tim Seidler, Malte Tiburcy, Maria Daskalaki, Ingo Kutschka, Buntaro Fujita, Stephan Ensminger, Felix Bremmer, Amir Moussavi, Huaxiao Yang, Xulei Qin, Sophie Mißbach, Charis Drummer, Hassina Baraki, Susann Boretius, Christopher Hasenauer, Tobias Nette, Johannes Kowallick, Christian O. Ritter, Joachim Lotz, Michael Didié, Mathias Mietsch, Tim Meyer, George Kensah, Dennis Krüger, Md Sadman Sakib, Lalit Kaurani, Andre Fischer, Ralf Dressel, Ignacio Rodriguez-Polo, Michael Stauske, Sebastian Diecke, Kerstin Maetz-Rensing, Eva Gruber-Dujardin, Martina Bleyer, Beatrix Petersen, Christian Roos, Liye Zhang, Lutz Walter, Silke Kaulfuß, Gökhan Yigit, Bernd Wollnik, Elif Levent, Berit Roshani, Christiane Stahl-Henning, Philipp Ströbel, Tobias Legler, Joachim Riggert, Kristian Hellenkamp, Jens-Uwe Voigt, Gerd Hasenfuß, Rabea Hinkel, Joseph C. Wu, Rüdiger Behr and Wolfram-Hubertus Zimmermann

Engineering a genomically recoded organism with one stop codon pp. 512-521

Michael W. Grome, Michael T. A. Nguyen, Daniel W. Moonan, Kyle Mohler, Kebron Gurara, Shenqi Wang, Colin Hemez, Benjamin J. Stenton, Yunteng Cao, Felix Radford, Maya Kornaj, Jaymin Patel, Maisha Prome, Svetlana Rogulina, David Sozanski, Jesse Tordoff, Jesse Rinehart and Farren J. Isaacs

Targeting protein–ligand neosurfaces with a generalizable deep learning tool pp. 522-531

Anthony Marchand, Stephen Buckley, Arne Schneuing, Martin Pacesa, Maddalena Elia, Pablo Gainza, Evgenia Elizarova, Rebecca M. Neeser, Pao-Wan Lee, Luc Reymond, Yangyang Miao, Leo Scheller, Sandrine Georgeon, Joseph Schmidt, Philippe Schwaller, Sebastian J. Maerkl, Michael Bronstein and Bruno E. Correia

How blowing the whistle on the Theranos scandal transformed Erika Cheung’s career pp. 533-535

Benjamin Plackett

I create buildings from mushroom components pp. 538-538

Miles Lizak

2025, volume 639, articles 8053

Author Correction: India–Eurasia convergence speed-up by passive-margin sediment subduction pp. E1-E1

Hao Zhou, Jiashun Hu, Luca Dal Zilio, Ming Tang, Keqing Li and Xiumian Hu

Vision: protecting and restoring a prized sense pp. S1-S1

Richard Hodson

Eye problems cloud NASA’s vision of Mars pp. S2-S3

Neil Savage

Author Correction: FANCD2–FANCI surveys DNA and recognizes double- to single-stranded junctions pp. E2-E2

Pablo Alcón, Artur P. Kaczmarczyk, Korak Kumar Ray, Themistoklis Liolios, Guillaume Guilbaud, Tamara Sijacki, Yichao Shen, Stephen H. McLaughlin, Julian E. Sale, Puck Knipscheer, David S. Rueda and Lori A. Passmore

Author Correction: Fetal hepatocytes protect the HSPC genome via fetuin-A pp. E3-E3

Xiao-Lin Guo, Yi-Ding Wang, Yan-Jun Liu, Lei Chu, Hua Zhu, Ye Hu, Ren-Yan Wu, Hong-Yu Xie, Juan Yu, Shui-Ping Li, Chao-Yang Xiong, Ruo-Yan Li, Fang Ke, Lei Chen, Guo-Qiang Chen, Liang Chen, Fan Bai, Tariq Enver, Guo-Hong Li, Huai-Fang Li and Deng-Li Hong

How can treatment for eye disease be made easier? pp. S4-S6

Katherine Bourzac

Author Correction: Seasonal advance of intense tropical cyclones in a warming climate pp. E4-E4

Kaiyue Shan, Yanluan Lin, Pao-Shin Chu, Xiping Yu and Fengfei Song

Publisher Correction: Immune evasion through mitochondrial transfer in the tumour microenvironment pp. E5-E5

Hideki Ikeda, Katsushige Kawase, Tatsuya Nishi, Tomofumi Watanabe, Keizo Takenaga, Takashi Inozume, Takamasa Ishino, Sho Aki, Jason Lin, Shusuke Kawashima, Joji Nagasaki, Youki Ueda, Shinichiro Suzuki, Hideki Makinoshima, Makiko Itami, Yuki Nakamura, Yasutoshi Tatsumi, Yusuke Suenaga, Takao Morinaga, Akiko Honobe-Tabuchi, Takehiro Ohnuma, Tatsuyoshi Kawamura, Yoshiyasu Umeda, Yasuhiro Nakamura, Yukiko Kiniwa, Eiki Ichihara, Hidetoshi Hayashi, Jun-ichiro Ikeda, Toyoyuki Hanazawa, Shinichi Toyooka, Hiroyuki Mano, Takuji Suzuki, Tsuyoshi Osawa, Masahito Kawazu and Yosuke Togashi

Publisher Correction: Skin autonomous antibody production regulates host–microbiota interactions pp. E6-E6

Inta Gribonika, Victor I. Band, Liang Chi, Paula Juliana Perez-Chaparro, Verena M. Link, Eduard Ansaldo, Cihan Oguz, Djenet Bousbaine, Michael A. Fischbach and Yasmine Belkaid

Restoring vision with optogenetics pp. S7-S9

Liam Drew

We moved a conference halfway around the globe to avoid visa discrimination pp. 9-9

Kara Hanson

Human echolocation can be taught pp. S10-S11

Simon Makin

Artificial intelligence could boost eye care in low-income countries pp. S12-S13

Tammy Worth

Postdocs and PhD students hit hard by Trump’s crackdown on science pp. 13-14

Heidi Ledford and Humberto Basilio

What sparked the COVID pandemic? Mounting evidence points to raccoon dogs pp. 14-15

Smriti Mallapaty

The search for solutions to geographic atrophy of the retina pp. S14-S16

Anthony King

Breast cancer is on the rise: data reveal drastic gap in survival rates pp. 16-16

Giorgia Guglielmi

How a junk-food splurge can change your brain activity pp. 17-18

Julian Nowogrodzki

US pulls back from gold-standard scientific climate panel pp. 17-17

Jeff Tollefson

NIH turmoil sparks anxiety over future of its global grants pp. 18-19

Smriti Mallapaty and Miryam Naddaf

‘Slime’ keeps the brain safe ― and could guard against ageing pp. 19-20

Heidi Ledford

Iconic ocean-current system is safe from climate collapse ― for now pp. 20-20

Humberto Basilio

How much energy will AI really consume? The good, the bad and the unknown pp. 22-24

Sophia Chen

The science of shopping addiction: what makes people buy loads of stuff? pp. 26-28

Emma Marris

Against the odds: 12 women who beat bias to succeed in science pp. 29-31

Georgina Ferry

Stories of people, past, present and future: Books in brief pp. 31-31

Andrew Robinson

Train clinical AI to reason like a team of doctors pp. 32-34

Christopher R. S. Banerji, Tapabrata Chakraborti, Aya Abdelsalam Ismail, Florian Ostmann and Ben D. MacArthur

Use your research to beat health inequities: four strategies from experts pp. 35-37

Lynn Hendricks, Raeka Aiyar, Uma Palanisamy and Nyasha Phanisa Sithole

AI hallucinations are a feature of LLM design, not a bug pp. 38-38

Joseph Dumit and Andreas Roepstorff

AI must be taught concepts, not just patterns in raw data pp. 38-38

Vinay K. Chaudhri

Elon Musk has some supporters in science pp. 38-38

Saleem H. Ali

Should scientists ditch the social-media platform X? pp. 38-38

Ivano Amelio

Revealing how fungi build planet-altering ‘road’ networks pp. 39-40

Neo D. Martinez and Gianna L. Marschmann

Amazonian deforestation makes the wet season wetter, and the dry season drier pp. 40-42

Wim Thiery

Molecular glue unexpectedly mimics the effect of cancer mutations pp. 42-43

Jonathan W. Bushman and Patrick Ryan Potts

AI algorithm helps telescopes to pivot fast towards gravitational-wave sources pp. 43-44

Michael J. Williams

Could psychedelics be fine-tuned to relieve anxiety but skip the ‘trip’? pp. 45-46

Cory A. Knox and Alex C. Kwan

Genetic and geographical origins of Eurasia’s influential Yamna culture pp. 46-47

Lehti Saag and Mait Metspalu

Real-time inference for binary neutron star mergers using machine learning pp. 49-53

Maximilian Dax, Stephen R. Green, Jonathan Gair, Nihar Gupte, Michael Pürrer, Vivien Raymond, Jonas Wildberger, Jakob H. Macke, Alessandra Buonanno and Bernhard Schölkopf

Multiplexed entanglement of multi-emitter quantum network nodes pp. 54-59

A. Ruskuc, C.-J. Wu, E. Green, S. L. N. Hermans, W. Pajak, J. Choi and A. Faraon

Spectroscopy of the fractal Hofstadter energy spectrum pp. 60-66

Kevin P. Nuckolls, Michael G. Scheer, Dillon Wong, Myungchul Oh, Ryan L. Lee, Jonah Herzog-Arbeitman, Kenji Watanabe, Takashi Taniguchi, Biao Lian and Ali Yazdani

Interplay of geometrical and spin chiralities in 3D twisted magnetic ribbons pp. 67-72

André M. A. Farinha, See-Hun Yang, Jiho Yoon, Banabir Pal and Stuart S. P. Parkin

Orbital hybridization in graphene-based artificial atoms pp. 73-78

Yue Mao, Hui-Ying Ren, Xiao-Feng Zhou, Hao Sheng, Yun-Hao Xiao, Yu-Chen Zhuang, Ya-Ning Ren, Lin He and Qing-Feng Sun

A single-fibre computer enables textile networks and distributed inference pp. 79-86

Nikhil Gupta, Henry Cheung, Syamantak Payra, Gabriel Loke, Jenny Li, Yongyi Zhao, Latika Balachander, Ella Son, Vivian Li, Samuel Kravitz, Sehar Lohawala, John Joannopoulos and Yoel Fink

Achieving kilowatt-scale elastocaloric cooling by a multi-cell architecture pp. 87-92

Guoan Zhou, Lingyun Zhang, Zexi Li, Peng Hua, Qingping Sun and Shuhuai Yao

Steering perovskite precursor solutions for multijunction photovoltaics pp. 93-101

Shuaifeng Hu, Junke Wang, Pei Zhao, Jorge Pascual, Jianan Wang, Florine Rombach, Akash Dasgupta, Wentao Liu, Minh Anh Truong, He Zhu, Manuel Kober-Czerny, James N. Drysdale, Joel A. Smith, Zhongcheng Yuan, Guus J. W. Aalbers, Nick R. M. Schipper, Jin Yao, Kyohei Nakano, Silver-Hamill Turren-Cruz, André Dallmann, M. Greyson Christoforo, James M. Ball, David P. McMeekin, Karl-Augustin Zaininger, Zonghao Liu, Nakita K. Noel, Keisuke Tajima, Wei Chen, Masahiro Ehara, René A. J. Janssen, Atsushi Wakamiya and Henry J. Snaith

Impact of Amazonian deforestation on precipitation reverses between seasons pp. 102-108

Yingzuo Qin, Dashan Wang, Alan D. Ziegler, Bojie Fu and Zhenzhong Zeng

Glacial isostatic adjustment reveals Mars’s interior viscosity structure pp. 109-113

A. Broquet, A.-C. Plesa, V. Klemann, B. C. Root, A. Genova, M. A. Wieczorek, M. Knapmeyer, J. C. Andrews-Hanna and D. Breuer

Contrasting drought sensitivity of Eurasian and North American grasslands pp. 114-118

Qiang Yu, Chong Xu, Honghui Wu, Yuguang Ke, Xiaoan Zuo, Wentao Luo, Haiyan Ren, Qian Gu, Hongqiang Wang, Wang Ma, Alan K. Knapp, Scott L. Collins, Jennifer A. Rudgers, Yiqi Luo, Yann Hautier, Chengjie Wang, Zhengwen Wang, Yong Jiang, Guodong Han, Yingzhi Gao, Nianpeng He, Juntao Zhu, Shikui Dong, Xiaoping Xin, Guirui Yu, Melinda D. Smith, Linghao Li and Xingguo Han

Maize monoculture supported pre-Columbian urbanism in southwestern Amazonia pp. 119-123

Umberto Lombardo, Lautaro Hilbert, McKenzie Bentley, Christopher Bronk Ramsey, Kate Dudgeon, Albert Gaitan-Roca, José Iriarte, Andrés G. Mejía Ramón, Sergio Quezada, Marco Raczka, Jennifer G. Watling, Eduardo Neves and Francis Mayle

A genomic history of the North Pontic Region from the Neolithic to the Bronze Age pp. 124-131

Alexey G. Nikitin, Iosif Lazaridis, Nick Patterson, Svitlana Ivanova, Mykhailo Videiko, Valentin Dergachev, Nadiia Kotova, Malcolm Lillie, Inna Potekhina, Marta Krenz-Niedbała, Sylwia Łukasik, Serhij Makhortykh, Virginie Renson, Henry Shephard, Gennadie Sirbu, Sofiia Svyryd, Taras Tkachuk, Piotr Włodarczak, Kim Callan, Elizabeth Curtis, Eadaoin Harney, Lora Iliev, Aisling Kearns, Ann Marie Lawson, Megan Michel, Matthew Mah, Adam Micco, Jonas Oppenheimer, Lijun Qiu, J. Noah Workman, Fatma Zalzala, Swapan Mallick, Nadin Rohland and David Reich

The genetic origin of the Indo-Europeans pp. 132-142

Iosif Lazaridis, Nick Patterson, David Anthony, Leonid Vyazov, Romain Fournier, Harald Ringbauer, Iñigo Olalde, Alexander A. Khokhlov, Egor P. Kitov, Natalia I. Shishlina, Sorin C. Ailincăi, Danila S. Agapov, Sergey A. Agapov, Elena Batieva, Baitanayev Bauyrzhan, Zsolt Bereczki, Alexandra Buzhilova, Piya Changmai, Andrey A. Chizhevsky, Ion Ciobanu, Mihai Constantinescu, Marietta Csányi, János Dani, Peter K. Dashkovskiy, Sándor Évinger, Anatoly Faifert, Pavel Flegontov, Alin Frînculeasa, Mădălina N. Frînculeasa, Tamás Hajdu, Tom Higham, Paweł Jarosz, Pavol Jelínek, Valeri I. Khartanovich, Eduard N. Kirginekov, Viktória Kiss, Alexandera Kitova, Alexeiy V. Kiyashko, Jovan Koledin, Arkady Korolev, Pavel Kosintsev, Gabriella Kulcsár, Pavel Kuznetsov, Rabadan Magomedov, Aslan M. Mamedov, Eszter Melis, Vyacheslav Moiseyev, Erika Molnár, Janet Monge, Octav Negrea, Nadezhda A. Nikolaeva, Mario Novak, Maria Ochir-Goryaeva, György Pálfi, Sergiu Popovici, Marina P. Rykun, Tatyana M. Savenkova, Vladimir P. Semibratov, Nikolai N. Seregin, Alena Šefčáková, Raikhan S. Mussayeva, Irina Shingiray, Vladimir N. Shirokov, Angela Simalcsik, Kendra Sirak, Konstantin N. Solodovnikov, Judit Tárnoki, Alexey A. Tishkin, Viktor Trifonov, Sergey Vasilyev, Ali Akbari, Esther S. Brielle, Kim Callan, Francesca Candilio, Olivia Cheronet, Elizabeth Curtis, Olga Flegontova, Lora Iliev, Aisling Kearns, Denise Keating, Ann Marie Lawson, Matthew Mah, Adam Micco, Megan Michel, Jonas Oppenheimer, Lijun Qiu, J. Noah Workman, Fatma Zalzala, Anna Szécsényi-Nagy, Pier Francesco Palamara, Swapan Mallick, Nadin Rohland, Ron Pinhasi and David Reich

Opponent control of reinforcement by striatal dopamine and serotonin pp. 143-152

Daniel F. Cardozo Pinto, Matthew B. Pomrenze, Michaela Y. Guo, Gavin C. Touponse, Allen P. F. Chen, Brandon S. Bentzley, Neir Eshel and Robert C. Malenka

Hippocampal neuronal activity is aligned with action plans pp. 153-161

Ipshita Zutshi, Athina Apostolelli, Wannan Yang, Zheyang Sam Zheng, Tora Dohi, Edoardo Balzani, Alex H. Williams, Cristina Savin and György Buzsáki

Fine-tuning gibberellin improves rice alkali–thermal tolerance and yield pp. 162-171

Shuang-Qin Guo, Ya-Xin Chen, Ya-Lin Ju, Chen-Yang Pan, Jun-Xiang Shan, Wang-Wei Ye, Nai-Qian Dong, Yi Kan, Yi-Bing Yang, Huai-Yu Zhao, Hong-Xiao Yu, Zi-Qi Lu, Jie-Jie Lei, Ben Liao, Xiao-Rui Mu, Ying-Jie Cao, Liangxing Guo, Jin Gao, Ji-Fu Zhou, Kai-Yang Yang, Hong-Xuan Lin and Youshun Lin

A travelling-wave strategy for plant–fungal trade pp. 172-180

Loreto Oyarte Galvez, Corentin Bisot, Philippe Bourrianne, Rachael Cargill, Malin Klein, Marije Son, Jaap Krugten, Victor Caldas, Thomas Clerc, Kai-Kai Lin, Félix Kahane, Simon Staalduine, Justin D. Stewart, Victoria Terry, Bianca Turcu, Sander Otterdijk, Antoine Babu, Marko Kamp, Marco Seynen, Bas Steenbeek, Jan Zomerdijk, Evelina Tutucci, Merlin Sheldrake, Christophe Godin, Vasilis Kokkoris, Howard A. Stone, E. Toby Kiers and Thomas S. Shimizu

Limited impact of Salmonella stress and persisters on antibiotic clearance pp. 181-189

Joseph Fanous, Beatrice Claudi, Vishwachi Tripathi, Jiagui Li, Frédéric Goormaghtigh and Dirk Bumann

Methanol transfer supports metabolic syntrophy between bacteria and archaea pp. 190-195

Yan Huang, Kensuke Igarashi, Laiyan Liu, Daisuke Mayumi, Tomomi Ujiie, Lin Fu, Min Yang, Yahai Lu, Lei Cheng, Souichiro Kato and Masaru K. Nobu

SARS-CoV-2 evolution on a dynamic immune landscape pp. 196-204

N. Alexia Raharinirina, Nils Gubela, Daniela Börnigen, Maureen Rebecca Smith, Djin-Ye Oh, Matthias Budt, Christin Mache, Claudia Schillings, Stephan Fuchs, Ralf Dürrwald, Thorsten Wolff, Martin Hölzer, Sofia Paraskevopoulou and Max Kleist

Antibody prophylaxis may mask subclinical SIV infections in macaques pp. 205-213

Christopher A. Gonelli, Hannah A. D. King, SungYoul Ko, Christine M. Fennessey, Nami Iwamoto, Rosemarie D. Mason, Ashley Heimann, Dillon R. Flebbe, John-Paul Todd, Kathryn E. Foulds, Brandon F. Keele, Jeffrey D. Lifson, Richard A. Koup and Mario Roederer

CD45-PET is a robust, non-invasive tool for imaging inflammation pp. 214-224

Ali Salehi Farid, Jennifer E. Rowley, Harris H. Allen, Isabella G. Kruger, Soheil Tavakolpour, Kyle Neeley, Min Cong, Haneyeh Shahbazian, Niki Dorafshani, Achraf Berrada, Alexander C. MacDonagh, Robert F. Padera, Pedro Brugarolas, Alan B. Packard, Matthew W. Rosenbaum, Sanjay Divakaran, Marcelo F. Carli and Mohammad Rashidian

De novo designed proteins neutralize lethal snake venom toxins pp. 225-231

Susana Vázquez Torres, Melisa Benard Valle, Stephen P. Mackessy, Stefanie K. Menzies, Nicholas R. Casewell, Shirin Ahmadi, Nick J. Burlet, Edin Muratspahić, Isaac Sappington, Max D. Overath, Esperanza Rivera- de-Torre, Jann Ledergerber, Andreas H. Laustsen, Kim Boddum, Asim K. Bera, Alex Kang, Evans Brackenbrough, Iara A. Cardoso, Edouard P. Crittenden, Rebecca J. Edge, Justin Decarreau, Robert J. Ragotte, Arvind S. Pillai, Mohamad Abedi, Hannah L. Han, Stacey R. Gerben, Analisa Murray, Rebecca Skotheim, Lynda Stuart, Lance Stewart, Thomas J. A. Fryer, Timothy P. Jenkins and David Baker

UM171 glues asymmetric CRL3–HDAC1/2 assembly to degrade CoREST corepressors pp. 232-240

Megan J. R. Yeo, Olivia Zhang, Xiaowen Xie, Eunju Nam, N. Connor Payne, Pallavi M. Gosavi, Hui Si Kwok, Irtiza Iram, Ceejay Lee, Jiaming Li, Nicholas J. Chen, Khanh Nguyen, Hanjie Jiang, Zhipeng A. Wang, Kwangwoon Lee, Haibin Mao, Stefan A. Harry, Idris A. Barakat, Mariko Takahashi, Amanda L. Waterbury, Marco Barone, Andrea Mattevi, Steven A. Carr, Namrata D. Udeshi, Liron Bar-Peled, Philip A. Cole, Ralph Mazitschek, Brian B. Liau and Ning Zheng

Converging mechanism of UM171 and KBTBD4 neomorphic cancer mutations pp. 241-249

Xiaowen Xie, Olivia Zhang, Megan J. R. Yeo, Ceejay Lee, Ran Tao, Stefan A. Harry, N. Connor Payne, Eunju Nam, Leena Paul, Yiran Li, Hui Si Kwok, Hanjie Jiang, Haibin Mao, Jennifer L. Hadley, Hong Lin, Melissa Batts, Pallavi M. Gosavi, Vincenzo D’Angiolella, Philip A. Cole, Ralph Mazitschek, Paul A. Northcott, Ning Zheng and Brian B. Liau

Structural insights into RNA cleavage by PIWI Argonaute pp. 250-259

Zhiqing Li, Qikui Xu, Jing Zhong, Yan Zhang, Tianxiang Zhang, Xiaoze Ying, Xiaoli Lu, Xiaoyi Li, Li Wan, Junchao Xue, Jing Huang, Ying Zhen, Zhao Zhang, Jianping Wu and En-Zhi Shen

Behind every great woman in science, there’s another great woman in science pp. 261-264

Amanda Heidt

ChatGPT for students: learners find creative new uses for chatbots pp. 265-266

Amanda Heidt

Tracking gulls to prevent a bird flu pandemic pp. 268-268

Miles Lizak