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2000, volume 408, articles 6815

Stem-cell work in the balance pp. 887-888

Matthew Davis

Tussle starts for research posts as Bush rides into Washington pp. 887-887

Tony Reichhardt and Paul Smaglik

New regime may aim to craft compromise on green issues pp. 888-888

Tony Reichhardt

NASA set to move Pluto back up its priority list pp. 889-889

Tony Reichhardt

Japanese genomics company offers shares in sequences pp. 889-889

David Cyranoski

Italian women meet glass ceiling in the lab pp. 890-891

Alison Abbott

International search underway in Italy for institute directors pp. 891-891

Alison Abbott

Beyond the book of life pp. 894-896

Peter Aldhous

A climate of uncertainty pp. 896-897

Heike Langenberg and Peter Aldhous

Panacea, or Pandora's box? pp. 897-898

Peter Aldhous

Where are they boldly going? pp. 898-899

Tony Reichhardt

Life is a game of numbers pp. 900-901

Marina Chicurel

In and out of Africa pp. 901-902

Declan Butler

Battling the killer proteins pp. 902-903

Peter Aldhous and Alison Abbott

When priorities collide pp. 903-903

Philip Ball

Molecular movers and shakers pp. 904-904

Philip Ball

Cloning's not a new idea: the Greeks had a word for it centuries ago pp. 905-905

A. A. Diamandopoulos and P. C. Goudas

Taiwan pays the price for growth, in toxic pollution pp. 905-905

Govindasamy Agoramoorthy and Minna J. Hsu

A diaspora and its blessings pp. 907-908

Walter Gratzer

Tuck in, and enjoy! pp. 908-909

Anthony Blake

Blood, gore and holey stomachs pp. 909-910

W. F. Bynum

Science in culture pp. 910-910

Vaclav Smil

Temptations of the tree pp. 911-911

Geir Hestmark

Monolith pp. 913-913

Ian Stewart and Jack Cohen

Model behaviour pp. 915-916

Paul F. Chapman

The Big Bang is bang on pp. 916-917

John Bahcall

Cooperation can be dangerous pp. 917-919

Richard H. Kessin

Measuring big G pp. 919-920

Terry Quinn

Moving forward by looking away pp. 921-923

Larry Snyder

Teaching magnets new tricks pp. 923-924

David D. Awschalom and Roland K. Kawakami

Oscillating opinion pp. 924-925

Heike Langenberg

Solid progress in ion conduction pp. 925-926

Alan V. Chadwick

Does the Queen speak the Queen's English? pp. 927-928

Jonathan Harrington, Sallyanne Palethorpe and Catherine I. Watson

Penguin fathers preserve food for their chicks pp. 928-929

Michel Gauthier-Clerc, Yvon Le Maho, Yannick Clerquin, Samuel Drault and Yves Handrich

Mistletoe seed dispersal by a marsupial pp. 929-930

Guillermo Amico and Marcelo A. Aizen

Penguin waddling is not wasteful pp. 929-929

Timothy M. Griffin and Rodger Kram

The cosmic microwave background radiation temperature at a redshift of 2.34 pp. 931-935

R. Srianand, P. Petitjean and C. Ledoux

Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms pp. 936-943

Lu Chen, Dane M. Chetkovich, Ronald S. Petralia, Neal T. Sweeney, Yoshimi Kawasaki, Robert J. Wenthold, David S. Bredt and Roger A. Nicoll

Electric-field control of ferromagnetism pp. 944-946

H. Ohno, D. Chiba, F. Matsukura, T. Omiya, E. Abe, T. Dietl, Y. Ohno and K. Ohtani

Mesoscopic fast ion conduction in nanometre-scale planar heterostructures pp. 946-949

N. Sata, K. Eberman, K. Eberl and J. Maier

Pairing of isolated nucleic-acid bases in the absence of the DNA backbone pp. 949-951

Eyal Nir, Karl Kleinermanns and Mattanjah S. de Vries

The influence of rivers on marine boron isotopes and implications for reconstructing past ocean pH pp. 951-954

D. Lemarchand, J. Gaillardet, É. Lewin and C. J. Allègre

Evidence from episodic seamount volcanism for pulsing of the Iceland plume in the past 70 Myr pp. 954-958

J. M. O'Connor, P. Stoffers, J. R. Wijbrans, P. M. Shannon and T. Morrissey

Subduction and collision processes in the Central Andes constrained by converted seismic phases pp. 958-961

X. Yuan, S. V. Sobolev, R. Kind, O. Oncken, G. Bock, G. Asch, B. Schurr, F. Graeber, A. Rudloff, W. Hanka, K. Wylegalla, R. Tibi, Ch. Haberland, A. Rietbrock, P. Giese, P. Wigger, P. Röwer, G. Zandt, S. Beck, T. Wallace, M. Pardo and D. Comte

Disturbance and diversity in experimental microcosms pp. 961-964

Angus Buckling, Rees Kassen, Graham Bell and Paul B. Rainey

Altruism and social cheating in the social amoeba Dictyostelium discoideum pp. 965-967

Joan E. Strassmann, Yong Zhu and David C. Queller

Asymmetric leaves1 mediates leaf patterning and stem cell function in Arabidopsis pp. 967-971

Mary E. Byrne, Ross Barley, Mark Curtis, Juana Maria Arroyo, Maitreya Dunham, Andrew Hudson and Robert A. Martienssen

Neuronal switching of sensorimotor transformations for antisaccades pp. 971-975

Mingsha Zhang and Shabtai Barash

A learning deficit related to age and β-amyloid plaques in a mouse model of Alzheimer's disease pp. 975-979

Guiquan Chen, Karen S. Chen, Jane Knox, Jennifer Inglis, Andrew Bernard, Stephen J. Martin, Alan Justice, Lisa McConlogue, Dora Games, Stephen B. Freedman and Richard G. M. Morris

Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease pp. 979-982

Christopher Janus, Jacqueline Pearson, JoAnne McLaurin, Paul M. Mathews, Ying Jiang, Stephen D. Schmidt, M. Azhar Chishti, Patrick Horne, Donna Heslin, Janet French, Howard T.J. Mount, Ralph A. Nixon, Marc Mercken, Catherine Bergeron, Paul E. Fraser, Peter St George-Hyslop and David Westaway

Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease pp. 982-985

Dave Morgan, David M. Diamond, Paul E. Gottschall, Kenneth E. Ugen, Chad Dickey, John Hardy, Karen Duff, Paul Jantzen, Giovanni DiCarlo, Donna Wilcock, Karen Connor, Jaime Hatcher, Caroline Hope, Marcia Gordon and Gary W. Arendash

Induction of vanilloid receptor channel activity by protein kinase C pp. 985-990

Louis S. Premkumar and Gerard P. Ahern

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents pp. 990-994

Kazushige Hanaoka, Feng Qian, Alessandra Boletta, Anil K. Bhunia, Klaus Piontek, Leonidas Tsiokas, Vikas P. Sukhatme, William B. Guggino and Gregory G. Germino

Hypoinsulinaemia, glucose intolerance and diminished β-cell size in S6K1-deficient mice pp. 994-997

Mario Pende, Sara C. Kozma, Muriel Jaquet, Viola Oorschot, Rémy Burcelin, Yannick Le Marchand-Brustel, Judith Klumperman, Bernard Thorens and George Thomas

Controlled growth factor release from synthetic extracellular matrices pp. 998-1000

Kuen Yong Lee, Martin C. Peters, Kenneth W. Anderson and David J. Mooney

A role for Saccharomyces cerevisiae histone H2A in DNA repair pp. 1001-1004

Jessica A. Downs, Noel F. Lowndes and Stephen P. Jackson

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain pp. 1004-1008

Zhihong Liu, Chaohong Sun, Edward T. Olejniczak, Robert P. Meadows, Stephen F. Betz, Thorsten Oost, Julia Herrmann, Joe C. Wu and Stephen W. Fesik

Structural basis of IAP recognition by Smac/DIABLO pp. 1008-1012

Geng Wu, Jijie Chai, Tomeka L. Suber, Jia-Wei Wu, Chunying Du, Xiaodong Wang and Yigong Shi

Correction: Digital selection and analogue amplification coexist in a cortex-inspired silicon circuit pp. 1012-1012

Richard H. R. Hahnloser, Rahul Sarpeshkar, Misha A. Mahowald, Rodney J. Douglas and H. Sebastian Seung

2000, volume 408, articles 6814

Japan to bypass bureaucracy by reshaping science ministries pp. 757-757

David Cyranoski and Robert Triendl

Germany sets up electronic archive pp. 757-757

Quirin Schiermeier

Forces for collaboration falter with human genome in sight pp. 758-758

Paul Smaglik

Faster sequencing slows down release of mouse gene data pp. 758-759

Paul Smaglik

Japan pins hopes on fast-breeder nuclear option pp. 759-759

David Cyranoski

Publication deal for Celera sparks row over data access pp. 759-759

Paul Smaglik

California invests $300 million in high tech pp. 760-760

Rex Dalton

Pesticides implicated in declining frog numbers pp. 760-760

Jessa Netting

Galapagos ecologists under threat from violent protests pp. 761-761

Mark Schrope

Virtual laboratory will recreate classic experiments pp. 761-761

Vera Bettenworth and Alison Abbott

Swimming against the tide pp. 764-766

David Cyranoski

... we need a metaphor to explain life's mystery pp. 767-768

Richard Strohman

Beefing about the risks posed by the French BSE epidemic pp. 767-767

John Krebs

Acid test finally wiped out vitalism, and yet pp. 767-767

Sidney Toby

Ecology needs theory as well as practice pp. 768-768

Brian A. Maurer

Pressure to meet current needs hinders science pp. 768-768

Rodney W. Nichols

Programmed for defence pp. 769-769

Fred Rosen

Gene games of the future pp. 769-770

Veronica van Heyningen

Extremophiles in the raw pp. 771-771

P. G. Willmer

A cellular cornucopia pp. 773-773

Margaret Buckingham

The holdouts pp. 775-775

George Zebrowski

Swimming in Flatsea pp. 777-778

Greg Huber

Head start pp. 778-781

John R. Finnerty

Five-fold symmetry in liquids pp. 781-782

Frans Spaepen

The case for an RNA enzyme pp. 782-783

Timothy W. Nilsen

Geometry spawns vortices pp. 783-785

Alan T. Dorsey

Volatile defence pp. 785-785

Amanda Tromans

Michael Smith (1932–2000) pp. 786-786

Michael R. Hayden and Victor Ling

Likely size of the French BSE epidemic pp. 787-788

Christl A. Donnelly

What you see is what you hear pp. 788-788

Ladan Shams, Yukiyasu Kamitani and Shinsuke Shimojo

Soil warming and organic carbon content pp. 789-790

Eric A. Davidson, Susan E. Trumbore and Ronald Amundson

reply: Soil warming and organic carbon content pp. 790-790

Christian P. Giardina and Michael G. Ryan

Now for the hard ones pp. 792-793

David Adam

A green chapter in the book of life pp. 794-795

Virginia Walbot

Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana pp. 816-820

Athanasios Theologis, Joseph R. Ecker, Curtis J. Palm, Nancy A. Federspiel, Samir Kaul, Owen White, Jose Alonso, Hootan Altafi, Rina Araujo, Cheryl L. Bowman, Shelise Y. Brooks, Eugen Buehler, April Chan, Qimin Chao, Huaming Chen, Rosa F. Cheuk, Christina W. Chin, Mike K. Chung, Lane Conn, Aaron B. Conway, Andrew R. Conway, Todd H. Creasy, Ken Dewar, Patrick Dunn, Pelin Etgu, Tamara V. Feldblyum, JiDong Feng, Betty Fong, Claire Y. Fujii, John E. Gill, Andrew D. Goldsmith, Brian Haas, Nancy F. Hansen, Beth Hughes, Lucas Huizar, Jonathan L. Hunter, Jennifer Jenkins, Chanda Johnson-Hopson, Shehnaz Khan, Elizabeth Khaykin, Christopher J. Kim, Hean L. Koo, Irina Kremenetskaia, David B. Kurtz, Andrea Kwan, Bao Lam, Stephanie Langin-Hooper, Andrew Lee, Jeong M. Lee, Catherine A. Lenz, Joycelyn. H. Li, YaPing Li, Xiaoying Lin, Shirley X. Liu, Zhaoying A. Liu, Jason S. Luros, Rama Maiti, Andre Marziali, Jennifer Militscher, Molly Miranda, Michelle Nguyen, William C. Nierman, Brian I. Osborne, Grace Pai, Jeremy Peterson, Paul K. Pham, Michael Rizzo, Timothy Rooney, Don Rowley, Hitomi Sakano, Steven L. Salzberg, Jody R. Schwartz, Paul Shinn, Audrey M. Southwick, Hui Sun, Luke J. Tallon, Gabriel Tambunga, Mitsue J. Toriumi, Christopher D. Town, Teresa Utterback, Susan Van Aken, Maria Vaysberg, Valentina S. Vysotskaia, Michelle Walker, Dongying Wu, Guixia Yu, Claire M. Fraser, J. Craig Venter and Ronald W. Davis

Geomagnetic intensity variations over the past 780 kyr obtained from near-seafloor magnetic anomalies pp. 827-832

Jeffrey S. Gee, Steven C. Cande, John A. Hildebrand, Katie Donnelly and Robert L. Parker

Symmetry-induced formation of antivortices in mesoscopic superconductors pp. 833-835

Liviu F. Chibotaru, Arnout Ceulemans, Vital Bruyndoncx and Victor V. Moshchalkov

Flexible filaments in a flowing soap film as a model for one-dimensional flags in a two-dimensional wind pp. 835-839

Jun Zhang, Stephen Childress, Albert Libchaber and Michael Shelley

Observation of five-fold local symmetry in liquid lead pp. 839-841

H. Reichert, O. Klein, H. Dosch, M. Denk, V. Honkimäki, T. Lippmann and G. Reiter

Role of sea surface temperature and soil-moisture feedback in the 1998 Oklahoma–Texas drought pp. 842-844

Song-You Hong and Eugenia Kalnay

Possible presence of high-pressure ice in cold subducting slabs pp. 844-847

Craig R. Bina and Alexandra Navrotsky

Analysis of an evolutionary species–area relationship pp. 847-850

Jonathan B. Losos and Dolph Schluter

Fluorescent pigments in corals are photoprotective pp. 850-853

Anya Salih, Anthony Larkum, Guy Cox, Michael Kühl and Ove Hoegh-Guldberg

Conservation and elaboration of Hox gene regulation during evolution of the vertebrate head pp. 854-857

Miguel Manzanares, Hiroshi Wada, Nobue Itasaki, Paul A. Trainor, Robb Krumlauf and Peter W. H. Holland

Performance monitoring by the supplementary eye field pp. 857-860

Veit Stuphorn, Tracy L. Taylor and Jeffrey D. Schall

High constitutive activity of native H3 receptors regulates histamine neurons in brain pp. 860-864

Séverine Morisset, Agnès Rouleau, Xavier Ligneau, Florence Gbahou, Joël Tardivel-Lacombe, Holger Stark, Walter Schunack, C. Robin Ganellin and Jean-Michel Arrang

Attenuation of FGF signalling in mouse β-cells leads to diabetes pp. 864-868

Alan W. Hart, Nathalie Baeza, Åsa Apelqvist and Helena Edlund

Phosphoglycerate kinase acts in tumour angiogenesis as a disulphide reductase pp. 869-873

Angelina J. Lay, Xing-Mai Jiang, Oliver Kisker, Evelyn Flynn, Anne Underwood, Rosemary Condron and Philip J. Hogg

Rapid exchange of histone H1.1 on chromatin in living human cells pp. 873-876

Melody A. Lever, John P. H. Th'ng, Xuejun Sun and Michael J. Hendzel

Dynamic binding of histone H1 to chromatin in living cells pp. 877-881

Tom Misteli, Akash Gunjan, Robert Hock, Michael Bustin and David T. Brown

Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome pp. 881-884

Shyue-Lee Yean, Gerald Wuenschell, John Termini and Ren-Jang Lin

2000, volume 408, articles 6813

Successes in fight to save ozone layer could close holes by 2050 pp. 627-627

Mark Schrope

Gridlock stalls NIH budget rise pp. 627-627

Paul Smaglik

US puts global collaboration at heart of AIDS effort pp. 628-628

Rex Dalton

Mars images may be legacy of lakeside view pp. 628-628

Tony Reichhardt

Scientists win vote of confidence from French public pp. 628-628

Declan Butler

NIH cash tied to compulsory training in good behaviour pp. 629-629

Rex Dalton

France opens door to use of embryos in stem-cell research pp. 629-629

Declan Butler

Medical schools in concert on research ethics pp. 630-630

Steve Nadis

Xenotransplantation opponents take FDA to court pp. 630-630

Paul Smaglik

Japan makes polluters pay after landmark court ruling pp. 631-631

David Cyranoski

Academics bid to transcend the Arab–Israeli conflict pp. 631-631

Haim Watzman

The great ice mystery pp. 634-636

Jon Copley

Island-hopping invaders hitch a ride with tourists in South Georgia pp. 637-637

Steven L. Chown and Kevin J. Gaston

Status of Japanese monkeys under debate pp. 637-637

Kunihiko Obata

Call for a fairer deal on grant applications pp. 637-637

Robert Dorazi

The quantum centennial pp. 639-641

Anton Zeilinger

All human life is here pp. 643-644

Vaclav Smil

An uncertain principal pp. 644-645

Daniel Greenberger

Observing the astronomer pp. 645-646

Dorrit Hoffleit

A chair of one's own pp. 647-647

Christine Wennerås and Agnes Wold

Murphy's cat pp. 649-649

Joan D. Vinge

What drives climate? pp. 651-652

Lee R. Kump

Not making waves pp. 651-651

Laura Garwin

A start for population genomics pp. 652-653

S. Blair Hedges

On the threshold of success pp. 653-655

Richard De La Rue and Chris Smith

Coping with human CO2 emissions pp. 656-657

Laura Serna and Carmen Fenoll

Mantle recycled in Sardinia pp. 657-659

Barry B. Hanan

A Toll for DNA vaccines pp. 659-660

Robert L. Modlin

Quantum theory's last challenge pp. 661-664

Giovanni Amelino-Camelia

An electoral butterfly effect pp. 665-666

Robert C. Sinclair, Melvin M. Mark, Sean E. Moore, Carrie A. Lavis and Alexander S. Soldat

A giant atomic slide-puzzle pp. 665-665

R. van Gastel, E. Somfai, W. van Saarloos and J.W.M. Frenken

Timing of the Martian dynamo pp. 666-667

G. Schubert, C. T. Russell and W. B. Moore

Docking of components in a bacterial complex pp. 667-668

Takashi Ishikawa, Michael R. Maurizi, David Belnap and Alasdair C. Steven

Docking of components in a bacterial complex pp. 668-668

Matthias Bochtler, Claudia Hartmann, Hyun Kyu Song, Ravishankar Ramachandran and Robert Huber

A new model for protein stereospecificity pp. 668-668

A. D. Mesecar and D. E. Koshland

Granite magma formation, transport and emplacement in the Earth's crust pp. 669-673

N. Petford, A. R. Cruden, K. J. W. McCaffrey and J.-L. Vigneresse

Fossiliferous Lana'i deposits formed by multiple events rather than a single giant tsunami pp. 675-681

Ken H. Rubin, Charles H. Fletcher and Clark Sherman

Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1 pp. 682-688

David K. Worthylake, Kent L. Rossman and John Sondek

An optical counterpart to the anomalous X-ray pulsar 4U0142+61 pp. 689-692

F. Hulleman, M. H. van Kerkwijk and S. R. Kulkarni

Direct observation of growth and collapse of a Bose–Einstein condensate with attractive interactions pp. 692-695

Jordan M. Gerton, Dmitry Strekalov, Ionut Prodan and Randall G. Hulet

Direct observation of molecular cooperativity near the glass transition pp. 695-698

E. Vidal Russell and N. E. Israeloff

Evidence for decoupling of atmospheric CO2 and global climate during the Phanerozoic eon pp. 698-701

Ján Veizer, Yves Godderis and Louis M. François

Evidence from Sardinian basalt geochemistry for recycling of plume heads into the Earth's mantle pp. 701-704

D. Gasperini, J. Blichert-Toft, D. Bosch, A. Del Moro, P. Macera, P. Télouk and F. Albarède

The smallest known non-avian theropod dinosaur pp. 705-708

Xing Xu, Zhonghe Zhou and Xiaolin Wang

Mitochondrial genome variation and the origin of modern humans pp. 708-713

Max Ingman, Henrik Kaessmann, Svante Pääbo and Ulf Gyllensten

The HIC signalling pathway links CO2 perception to stomatal development pp. 713-716

Julie E. Gray, Geoff H. Holroyd, Frederique M. van der Lee, Ahmad R. Bahrami, Peter C. Sijmons, F. Ian Woodward, Wolfgang Schuch and Alistair M. Hetherington

The ELF3 zeitnehmer regulates light signalling to the circadian clock pp. 716-720

Harriet G. McWatters, Ruth M. Bastow, Anthony Hall and Andrew J. Millar

μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence pp. 720-723

Laura M. Bohn, Raul R. Gainetdinov, Fang-Tsyr Lin, Robert J. Lefkowitz and Marc G. Caron

Tyrosine-kinase-dependent recruitment of RGS12 to the N-type calcium channel pp. 723-727

Max L. Schiff, David P. Siderovski, J. Dedrick Jordan, Greg Brothers, Bryan Snow, Luc De Vries, Daniel F. Ortiz and María Diversé-Pierluissi

Adherens junctions and β-catenin-mediated cell signalling in a non-metazoan organism pp. 727-731

Mark J. Grimson, Juliet C. Coates, Jonathan P. Reynolds, Mark Shipman, Richard L. Blanton and Adrian J. Harwood

IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling pp. 732-735

Hiroaki Miki, Hideki Yamaguchi, Shiro Suetsugu and Tadaomi Takenawa

InsP4 facilitates store-operated calcium influx by inhibition of InsP3 5-phosphatase pp. 735-740

Meredith C. Hermosura, Hiroshi Takeuchi, Andrea Fleig, Andrew M. Riley, Barry V. L. Potter, Masato Hirata and Reinhold Penner

A Toll-like receptor recognizes bacterial DNA pp. 740-745

Hiroaki Hemmi, Osamu Takeuchi, Taro Kawai, Tsuneyasu Kaisho, Shintaro Sato, Hideki Sanjo, Makoto Matsumoto, Katsuaki Hoshino, Hermann Wagner, Kiyoshi Takeda and Shizuo Akira

Structure of the bacteriophage φ29 DNA packaging motor pp. 745-750

Alan A. Simpson, Yizhi Tao, Petr G. Leiman, Mohammed O. Badasso, Yongning He, Paul J. Jardine, Norman H. Olson, Marc C. Morais, Shelley Grimes, Dwight L. Anderson, Timothy S. Baker and Michael G. Rossmann

Erratum: Logical computation using algorithmic self-assembly of DNA triple-crossover molecules pp. 750-750

Chengde Mao, Thomas H. LaBean, John H. Reif and Nadrian Seeman

Erratum: Acceleration of global warming due to carbon-cycle feedbacks in a coupled climate model pp. 750-750

Peter M. Cox, Richard A. Betts, Chris D. Jones, Steven A. Spall and Ian J. Totterdell

Correction: Allometric scaling of production and life-history variation in vascular plants pp. 750-750

Brian J. Enquist, Geoffrey B. West, Eric L. Charnov and James H. Brown

Vaccine centres unite specialists in the battle against infectious diseases pp. 753-754

Diane Gershon

Developing countries and poorest people targeted by UN centre pp. 754-754

Diane Gershon

2000, volume 408, articles 6812

Wellcome Trust funds bid to unravel zebrafish genome pp. 503-503

Declan Butler

Deadlock in The Hague, but hopes remain for spring climate deal pp. 503-504

David Dickson

Argentinian researchers fight government plans for reform pp. 504-504

Xavier Bosch

German universities used forced labour pp. 504-505

Christina Hohmann

NASA U-turns enrage planetary scientists pp. 505-505

William Triplett

Dispute over rock dating settled out of court pp. 506-506

Rex Dalton

Germany rues 'complacency' over BSE testing strategy pp. 506-506

Alison Abbott and Quirin Schiermeier

Chinese science goes to Earth pp. 506-506

David Cyranoski

Britain plumps for support of big projects pp. 507-507

Peter Aldhous

... but ESO membership comes at a price pp. 507-507

Peter Aldhous

To the planets on a shoestring pp. 510-512

Robert Adler

Bernoulli was ahead of modern epidemiology pp. 513-514

Klaus Dietz and J. A. P. Heesterbeek

Important differences between sources of embryonic stem cells pp. 513-513

Anne McLaren

Weak euro hits PhDs too pp. 513-513

Luis Graca, Susana Nery, Monica Bettencourt Dias and Tiago Magalhaes

Aquaculture: part of the problem, not a solution pp. 514-514

Julio E. Pérez, Mauro Nirchio and Juan A. Gomez

Funding would prevent waste of research time pp. 514-514

Pedro Martínez

Innovations to stir young minds pp. 515-516

Howard P. Segal

Spiders need friends too pp. 516-517

Jeremy N. McNeil

Presents you may want to read as well pp. 516-516

Tim Brosnan

The facts of life and death pp. 517-518

Andrew Berry

Empirical curiosity... in verse pp. 518-518

Maurice Riordan

Trailing nature pp. 518-519

Sandra Knapp

Dinos all around pp. 519-520

Kevin Padian

Launching kids' minds into space pp. 520-521

Monica M. Grady

Images of Earth pp. 521-522

Lawrence W. Braile

Hurricanes and lightning pp. 522-522

Cornelia Lüdecke

Horribly fun and dreadfully popular! pp. 522-522

Sandra Knapp

What dreams may come? pp. 523-523

Paolo Mazzarello

Too many memories pp. 525-525

Pamela Sargent

Fighting the Ebola virus pp. 527-528

Dennis R. Burton and Paul W. H. I. Parren

C60 — the hole story pp. 528-529

Olle Gunnarsson

The problem of variation pp. 529-531

David L. Stern

Pinning on impact pp. 531-531

Magdalena Helmer

Chile refuges pp. 532-533

Peter D. Moore

Shaking faults loose pp. 533-535

Chris Marone

Bone versus immune system pp. 535-536

Joseph R. Arron and Yongwon Choi

A stable binary quasicrystal pp. 537-538

A. P. Tsai, J. Q. Guo, E. Abe, H. Takakura and T. J. Sato

Cultural revolution in whale songs pp. 537-537

Michael J. Noad, Douglas H. Cato, M. M. Bryden, Micheline -N. Jenner and K. Curt S. Jenner

DNA methylation in Drosophila melanogaster pp. 538-540

Frank Lyko, Bernard H. Ramsahoye and Rudolf Jaenisch

Numismatic gyrations pp. 540-540

Ger van den Engh, Peter Nelson and Jared Roach

Numismatic gyrations pp. 540-540

H. K. Moffatt

Electronics using hybrid-molecular and mono-molecular devices pp. 541-548

C. Joachim, J. K. Gimzewski and A. Aviram

Superconductivity at 52 K in hole-doped C60 pp. 549-552

J. H. Schön, Ch. Kloc and B. Batlogg

Genetic control and evolution of sexually dimorphic characters in Drosophila pp. 553-559

Artyom Kopp, Ian Duncan and Sean B. Carroll

Evidence against a redshift z > 6 for the galaxy STIS123627+621755 pp. 560-562

Daniel Stern, Peter Eisenhardt, Hyron Spinrad, Steve Dawson, Wil van Breugel, Arjun Dey, Wim de Vries and S. A. Stanford

Unusual spectral energy distribution of a galaxy previously reported to be at redshift 6.68 pp. 562-564

Hsiao-Wen Chen, Kenneth M. Lanzetta, Sebastian Pascarelle and Noriaki Yahata

First-order transition in confined water between high-density liquid and low-density amorphous phases pp. 564-567

Kenichiro Koga, Hideki Tanaka and X. C. Zeng

Changes in deep-water formation during the Younger Dryas event inferred from 10Be and 14C records pp. 567-570

Raimund Muscheler, Jürg Beer, Gerhard Wagner and Robert C. Finkel

Triggering of earthquake aftershocks by dynamic stresses pp. 570-574

Deborah Kilb, Joan Gomberg and Paul Bodin

Geochemical evidence for terrestrial ecosystems 2.6 billion years ago pp. 574-578

Yumiko Watanabe, Jacques E. J. Martini and Hiroshi Ohmoto

Nutritional constraints in terrestrial and freshwater food webs pp. 578-580

James J. Elser, William F. Fagan, Robert F. Denno, Dean R. Dobberfuhl, Ayoola Folarin, Andrea Huberty, Sebastian Interlandi, Susan S. Kilham, Edward McCauley, Kimberly L. Schulz, Evan H. Siemann and Robert W. Sterner

Bacterial dehalorespiration with chlorinated benzenes pp. 580-583

Lorenz Adrian, Ulrich Szewzyk, Jörg Wecke and Helmut Görisch

Calcium stores regulate the polarity and input specificity of synaptic modification pp. 584-588

Makoto Nishiyama, Kyonsoo Hong, Katsuhiko Mikoshiba, Mu-ming Poo and Kunio Kato

Analysis of calcium channels in single spines using optical fluctuation analysis pp. 589-593

Bernardo L. Sabatini and Karel Svoboda

Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast pp. 593-596

Tomokazu Ohshiro, Takako Yagami, Chuan Zhang and Fumio Matsuzaki

The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts pp. 596-600

Chian-Yu Peng, Laurina Manning, Roger Albertson and Chris Q. Doe

T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ pp. 600-605

Hiroshi Takayanagi, Kouetsu Ogasawara, Shigeaki Hida, Tomoki Chiba, Shigeo Murata, Kojiro Sato, Akinori Takaoka, Taeko Yokochi, Hiromi Oda, Keiji Tanaka, Kozo Nakamura and Tadatsugu Taniguchi

Development of a preventive vaccine for Ebola virus infection in primates pp. 605-609

Nancy J. Sullivan, Anthony Sanchez, Pierre E. Rollin, Zhi-yong Yang and Gary J. Nabel

Coenzyme Q is an obligatory cofactor for uncoupling protein function pp. 609-613

Karim S. Echtay, Edith Winkler and Martin Klingenberg

The PSI-H subunit of photosystem I is essential for state transitions in plant photosynthesis pp. 613-615

Christina Lunde, Poul Erik Jensen, Anna Haldrup, Juergen Knoetzel and Henrik Vibe Scheller

addendum: Magnetoresistance from quantum interference effects in ferromagnets pp. 616-616

N. Manyala, Y. Sidis, J. F. DiTusa, G. Aeppli, D. P. Young and Z. Fisk

Correction: Ultrasensitive pheromone detection by mammalian vomeronasal neurons pp. 616-616

Trese Leinders-Zufall, Andrew P. Lane, Adam C. Puche, Weidong Ma, Milos V. Novotny, Michael T. Shipley and Frank Zufall

Erratum: Tom22 is a multifunctional organizer of the mitochondrial preprotein translocase pp. 616-616

Sandra van Wilpe, Michael T. Ryan, Kerstin Hill, Ammy C. Maarse, Chris Meisinger, Jan Brix, Peter J. T. Dekker, Martin Moczko, Richard Wagner, Michiel Meijer, Bernard Guiard, Angelika Hönlinger and Nikolaus Pfanner

Erratum: Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1 pp. 616-616

Stacey S. Huppert, Anh Le, Eric H. Schroeter, Jeffrey S. Mumm, Meera T. Saxena, Laurie A. Milner and Raphael Kopan

Governments prime basic nanotech research, applied activity yet to soar pp. 619-620

Helen Gavaghan

Britain turns its attention to nanotech transfer pp. 620-621

Alok Jha

US industry starts to think big by acting small pp. 621-622

Paul Smaglik

A flexible approach pp. 621-621

Alok Jha

Building for the future pp. 622-622

Paul Smaglik

Canada tries to limit nanotech brain drain pp. 623-623

David Spurgeon

Nanotech undergrad course available pp. 623-623

David Spurgeon

Japan sets sights on success in nanotechnology pp. 624-624

David Cyranoski

Land of opportunity pp. 624-624

David Cyranoski

2000, volume 408, articles 6811

Anthropologists in turmoil over allegations of misconduct pp. 391-391

Rex Dalton

Partners edge closer to vital step on fusion pp. 392-392

Quirin Schiermeier

French target research money at allaying BSE fears pp. 392-392

Declan Butler

Europe boosts genome resource centres pp. 393-393

Alison Abbott

... as German genomics gets cash windfall pp. 393-393

Alison Abbott

Placebos could improve link between medical outlooks pp. 394-394

Paul Smaglik

Researchers fail to find signs of life in 'living' particles pp. 394-394

Alison Abbott

Biotech report dubbed 'worthless' pp. 394-394

Haim Watzman

Governments urged to rethink dam projects pp. 395-395

Mark Schrope

Aventis gets short shrift over release of modified corn pp. 395-395

Jessa Netting

Russia's prize fighter pp. 398-399

Quirin Schiermeier

Fruitfly centre spreads its wings pp. 400-401

Rex Dalton

Revolution in references: give readers a chance by putting page numbers pp. 402-402

Steve Wise

Speaking in too many tongues pp. 403-404

Massimo Piattelli-Palmarini

Celebrating blurry boundaries pp. 404-405

Steven Vogel

Observations of a travelling naturalist pp. 405-406

Janet Browne

Science in culture pp. 406-406

Martin Kemp

Brain drain pp. 409-409

Frederik Pohl

Gaining light from silicon pp. 411-412

Leigh Canham

Local or global? pp. 412-415

Shelley L. Berger

Clipping the carbon–carbon bond pp. 415-416

Robert H. Crabtree

Déjà vu pp. 416-417

J. J. Bull

Pore characterization pp. 417-417

Vincent Dusastre

Control by combinatorial codes pp. 419-420

Arjumand Ghazi and K. VijayRaghavan

Gene therapy for rats and mice pp. 420-421

Jerrold M. Olefsky

A dual-action material pp. 421-422

Fernando Palacio and Joel S. Miller

Lovely grub pp. 422-422

John Whitfield

A 1, 2, 3 in light microscopy pp. 423-424

Graham A. Dunn

Older bull elephants control young males pp. 425-426

Rob Slotow, Gus van Dyk, Joyce Poole, Bruce Page and Andre Klocke

C66 fullerene encaging a scandium dimer pp. 426-427

Chun-Ru Wang, Tsutomu Kai, Tetsuo Tomiyama, Takuya Yoshida, Yuji Kobayashi, Eiji Nishibori, Masaki Takata, Makoto Sakata and Hisanori Shinohara

A stable non-classical metallofullerene family pp. 427-428

S. Stevenson, P. W. Fowler, T. Heine, J. C. Duchamp, G. Rice, T. Glass, K. Harich, E. Hajdu, R. Bible and H. C. Dorn

The 'feathers' of Longisquama pp. 428-428

Robert R. Reisz and Hans-Dieter Sues

In search of the tumour-suppressor functions of BRCA1 and BRCA2 pp. 429-432

Ralph Scully and David M. Livingston

The DNA damage response: putting checkpoints in perspective pp. 433-439

Bin-Bing S. Zhou and Stephen J. Elledge

Optical gain in silicon nanocrystals pp. 440-444

L. Pavesi, L. Dal Negro, C. Mazzoleni, G. Franzò and F. Priolo

Evolution of the Sun's large-scale magnetic field since the Maunder minimum pp. 445-447

S. K. Solanki, M. Schüssler and M. Fligge

Coexistence of ferromagnetism and metallic conductivity in a molecule-based layered compound pp. 447-449

Eugenio Coronado, José R. Galán-Mascarós, Carlos J. Gómez-García and Vladimir Laukhin

Direct imaging of the pores and cages of three-dimensional mesoporous materials pp. 449-453

Yasuhiro Sakamoto, Mizue Kaneda, Osamu Terasaki, Dong Yuan Zhao, Ji Man Kim, Galen Stucky, Hyun June Shin and Ryong Ryoo

Improved estimates of global ocean circulation, heat transport and mixing from hydrographic data pp. 453-457

Alexandre Ganachaud and Carl Wunsch

The use of earthquake rate changes as a stress meter at Kilauea volcano pp. 457-460

James Dieterich, Valérie Cayol and Paul Okubo

Concurrent density dependence and independence in populations of arctic ground squirrels pp. 460-463

Tim J. Karels and Rudy Boonstra

Variation in the reversibility of evolution pp. 463-466

Henrique Teotónio and Michael R. Rose

Integration of target and body-part information in the premotor cortex when planning action pp. 466-470

Eiji Hoshi and Jun Tanji

MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans pp. 470-475

Rajesh Ranganathan, Stephen C. Cannon and H. Robert Horvitz

Notch signalling and the synchronization of the somite segmentation clock pp. 475-479

Yun-Jin Jiang, Birgit L. Aerne, Lucy Smithers, Catherine Haddon, David Ish-Horowicz and Julian Lewis

Binding of disease-associated prion protein to plasminogen pp. 479-483

Michael B. Fischer, Christiane Roeckl, Petra Parizek, Hans Peter Schwarz and Adriano Aguzzi

Remission in models of type 1 diabetes by gene therapy using a single-chain insulin analogue pp. 483-488

Hyun Chul Lee, Su-Jin Kim, Kyung-Sup Kim, Hang-Cheol Shin and Ji-Won Yoon

A ubiquitin-like system mediates protein lipidation pp. 488-492

Yoshinobu Ichimura, Takayoshi Kirisako, Toshifumi Takao, Yoshinori Satomi, Yasutsugu Shimonishi, Naotada Ishihara, Noboru Mizushima, Isei Tanida, Eiki Kominami, Mariko Ohsumi, Takeshi Noda and Yoshinori Ohsumi

Gαi and Gαo are target proteins of reactive oxygen species pp. 492-495

Motohiro Nishida, Yoshiko Maruyama, Rie Tanaka, Kenji Kontani, Taku Nagao and Hitoshi Kurose

Global histone acetylation and deacetylation in yeast pp. 495-498

Maria Vogelauer, Jiansheng Wu, Noriyuki Suka and Michael Grunstein

Erratum: An intrinsic but cell-nonautonomous defect in GATA-1-overexpressing mouse erythroid cells pp. 498-498

David Whyatt, Fokke Lindeboom, Alar Karis, Rita Ferreira, Eric Milot, Rudi Hendriks, Marella de Bruijin, An Langeveld, Joost Gribnau, Frank Grosveld and Sjaak Philipsen

Erratum: Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins pp. 498-498

Anna Lasorella, Michela Noseda, Mercedes Beyna, Yoshifumi Yokota and Antonio Iavarone

2000, volume 408, articles 6810

European panel rejects creation of human embryos for research pp. 277-277

David Dickson

Online naming of species opens digital age for taxonomy pp. 278-278

Henry Gee

Political uncertainty halts bioprospecting in Mexico pp. 278-278

Rex Dalton

Climate talks face uncertainty over US strategy pp. 279-279

Tony Reichhardt

Election impasse leaves science in the dark pp. 279-279

Tony Reichhardt and Paul Smaglik

Row over fate of endangered monkeys pp. 280-280

David Cyranoski

Fake finds reveal critical deficiency pp. 280-280

David Cyranoski

Promise of Higgs fails to save CERN collider pp. 281-281

Alison Abbott

Medical institute opens amid hopes of Kansas rebirth pp. 281-281

Paul Smaglik

Slimebusters pp. 284-286

Marina Chicurel

Ancestors knew how to harness horsepower pp. 287-288

François Sigaut

Why are AIDS dissidents still making 15-year-old, long-refuted claims? pp. 287-287

Martin Delaney

Mildest organochlorines still cause toxic pollution pp. 287-287

Jonathan R. Latham

... so animals could pull their weight, and more pp. 288-288

Michael R. Goe

Award organizers should have noted the paper pp. 288-288

Justin Kruger

Fraud: retracted articles are still being cited pp. 288-288

Juan Miguel Campanario

Technology's tortoise and hare pp. 289-290

Stanford Ovshinsky

Physics of the money markets pp. 290-291

Blake LeBaron

A cosmological bouquet pp. 291-292

Giovanni F. Bignami

Science in culture pp. 292-292

Mark A. Elgar

Nice work — but is it science? pp. 293-293

Jim Smith

At the zoo pp. 295-295

Warren Ellis

Plotting the pyramids pp. 297-298

Owen Gingerich

Fish found in flagrante delicto pp. 298-299

Mark Kirkpatrick

Breathing life into an old model pp. 299-301

Tom Giebultowicz

It's not a gas pp. 301-302

Hermann W. Bange

Cardiac arrest can be less of a gamble pp. 302-302

Tim Lincoln

The legacy of a lonely life pp. 303-303

Leslie Sage

Mitochondrial genes on the move pp. 303-305

Michael W. Gray

Real brains for real robots pp. 305-306

Sandro Mussa-Ivaldi

Surfing the p53 network pp. 307-310

Bert Vogelstein, David Lane and Arnold J. Levine

Tracing the geographical origin of cocaine pp. 311-312

James R. Ehleringer, John F. Casale, Michael J. Lott and Valerie L. Ford

Detecting milk proteins in ancient pots pp. 312-312

Oliver Craig, Jacqui Mulville, Mike Parker Pearson, Robert Sokol, Keith Gelsthorpe, Rebecca Stacey and Matthew Collins

Feedback control of intercellular signalling in development pp. 313-319

Matthew Freeman

Ancient Egyptian chronology and the astronomical orientation of pyramids pp. 320-324

Kate Spence

Functional genomic analysis of C. elegans chromosome I by systematic RNA interference pp. 325-330

Andrew G. Fraser, Ravi S. Kamath, Peder Zipperlen, Maruxa Martinez-Campos, Marc Sohrmann and Julie Ahringer

Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III pp. 331-336

Pierre Gönczy, Christophe Echeverri, Karen Oegema, Alan Coulson, Steven J. M. Jones, Richard R. Copley, John Duperon, Jeff Oegema, Michael Brehm, Etienne Cassin, Eva Hannak, Matthew Kirkham, Silke Pichler, Kathrin Flohrs, Anoesjka Goessen, Sebastian Leidel, Anne-Marie Alleaume, Cécilie Martin, Nurhan Özlü, Peer Bork and Anthony A. Hyman

Mean-field cluster model for the critical behaviour of ferromagnets pp. 337-339

Ralph V. Chamberlin

Universal quantum computation with the exchange interaction pp. 339-342

D. P. DiVincenzo, D. Bacon, J. Kempe, G. Burkard and K. B. Whaley

Kondo physics in carbon nanotubes pp. 342-346

Jesper Nygård, David Henry Cobden and Poul Erik Lindelof

Increased marine production of N2O due to intensifying anoxia on the Indian continental shelf pp. 346-349

S. W. A. Naqvi, D. A. Jayakumar, P. V. Narvekar, H. Naik, V. V. S. S. Sarma, W. D'Souza, Samson Joseph and M. D. George

Microseismological evidence for a changing wave climate in the northeast Atlantic Ocean pp. 349-352

I. Grevemeyer, R. Herber and H.-H. Essen

Fine-scale genetic structuring on Manacus manacus leks pp. 352-353

Lisa Shorey, Stuart Piertney, Jon Stone and Jacob Höglund

Repeated, recent and diverse transfers of a mitochondrial gene to the nucleus in flowering plants pp. 354-357

Keith L. Adams, Daniel O. Daley, Yin-Long Qiu, James Whelan and Jeffrey D. Palmer

Imagery neurons in the human brain pp. 357-361

Gabriel Kreiman, Christof Koch and Itzhak Fried

Real-time prediction of hand trajectory by ensembles of cortical neurons in primates pp. 361-365

Johan Wessberg, Christopher R. Stambaugh, Jerald D. Kralik, Pamela D. Beck, Mark Laubach, John K. Chapin, Jung Kim, S. James Biggs, Mandayam A. Srinivasan and Miguel A. L. Nicolelis

A regulator of transcriptional elongation controls vertebrate neuronal development pp. 366-369

Su Guo, Yuki Yamaguchi, Sarah Schilbach, Tadashi Wada, James Lee, Audrey Goddard, Dorothy French, Hiroshi Handa and Arnon Rosenthal

ClC-5 Cl--channel disruption impairs endocytosis in a mouse model for Dent's disease pp. 369-373

Nils Piwon, Willy Günther, Michael Schwake, Michael R. Bösl and Thomas J. Jentsch

The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5 pp. 374-377

Letizia Lanzetti, Vladimir Rybin, Maria Grazia Malabarba, Savvas Christoforidis, Giorgio Scita, Marino Zerial and Pier Paolo Di Fiore

Deacetylation of p53 modulates its effect on cell growth and apoptosis pp. 377-381

Jianyuan Luo, Fei Su, Delin Chen, Ariel Shiloh and Wei Gu

Insights into SCF ubiquitin ligases from the structure of the Skp1–Skp2 complex pp. 381-386

Brenda A. Schulman, Andrea C. Carrano, Philip D. Jeffrey, Zachary Bowen, Elspeth R. E. Kinnucan, Michael S. Finnin, Stephen J. Elledge, J. Wade Harper, Michele Pagano and Nikola P. Pavletich

2000, volume 408, articles 6809

Emphasis of NASA's microgravity research shifts to space biology pp. 123-124

Tony Reichhardt

US grad students win union rights pp. 123-123

Paul Smaglik

Mexican science waits to see if election promises are met pp. 124-124

Marina Chicurel

Pesticide use linked to Parkinson's disease pp. 125-125

David Adam

Unprecedented gift boosts basic physics in Canada pp. 125-125

David Spurgeon

Court young French postdocs, says petition pp. 126-126

Declan Butler

...as changes at the top suggest action ahead pp. 126-126

Declan Butler

Japan's GM corn will undergo tests pp. 126-126

David Cyranoski

Indian biotech centre rocked by controversy pp. 127-127

K. S. Jayaraman

Structures by numbers pp. 130-132

Alison Abbott

Farming will only be sustainable when local people are truly involved pp. 133-133

Willy H. Verheye

Guidelines work better than animal welfare law pp. 133-133

Mary J. C. Hendrix

Wrong signals about alliance's scope and aim pp. 133-133

Alfred G. Gilman

Helping western forests heal pp. 135-136

William Wallace Covington

Anthropologists under fire pp. 137-138

Robert N. Proctor

Across the industrial divide pp. 139-140

Anthony Vice

Science in culture pp. 140-140

Roy Porter

The sounds of silence pp. 141-141

Robert C. Young

Ars longa, vita brevis pp. 143-143

James Alan Gardner

Ancient food for thought pp. 145-146

Warwick Bray

A most interesting factor pp. 146-147

Richard Bucala

A lake's life is not its own pp. 149-150

George W. Kling

Moving targets pp. 150-151

James C. Carrington

In control of molecular motion pp. 151-153

Ben L. Feringa

Flow charts pp. 153-153

Detlef Stammer

Intimate attention pp. 154-155

Jochen Braun

That sinking feeling pp. 155-156

Jorge Sarmiento

Invasive alga reaches California pp. 157-158

O. Jousson, J. Pawlowski, L. Zaninetti, F. W. Zechman, F. Dini, G. Di Guiseppe, R. Woodfield, A. Millar and A. Meinesz

Phase radiography with neutrons pp. 158-159

B. E. Allman, P. J. McMahon, K. A. Nugent, D. Paganin, D. L. Jacobson, M. Arif and S. A. Werner

Rivers, blood and transportation networks pp. 159-160

Peter K. Haff

Rivers, blood and transportation networks pp. 159-159

Page R. Painter

reply: Rivers, blood and transportation networks pp. 160-160

Jayanth R. Banavar, Amos Maritan and Andrea Rinaldo

Chemical and biological trends during lake evolution in recently deglaciated terrain pp. 161-166

Daniel R. Engstrom, Sherilyn C. Fritz, James E. Almendinger and Stephen Juggins

Structure and assembly of the Alu domain of the mammalian signal recognition particle pp. 167-173

Oliver Weichenrieder, Klemens Wild, Katharina Strub and Stephen Cusack

New high-pressure phases of lithium pp. 174-178

M. Hanfland, K. Syassen, N. E. Christensen and D. L. Novikov

Reversible phase transitions in polymer gels induced by radiation forces pp. 178-181

Saulius Juodkazis, Naoki Mukai, Ryosuke Wakaki, Akira Yamaguchi, Shigeki Matsuo and Hiroaki Misawa

An enantiomerically pure hydrogen-bonded assembly pp. 181-184

Leonard J. Prins, Feike De Jong, Peter Timmerman and David N. Reinhoudt

Acceleration of global warming due to carbon-cycle feedbacks in a coupled climate model pp. 184-187

Peter M. Cox, Richard A. Betts, Chris D. Jones, Steven A. Spall and Ian J. Totterdell

Offset of the potential carbon sink from boreal forestation by decreases in surface albedo pp. 187-190

Richard A. Betts

An artificial landscape-scale fishery in the Bolivian Amazon pp. 190-193

Clark L. Erickson

Spatial synchronization of vole population dynamics by predatory birds pp. 194-196

Rolf A. Ims and Harry P. Andreassen

Tracking an object through feature space pp. 196-199

Erik Blaser, Zenon W. Pylyshyn and Alex O. Holcombe

Distinct functions of the two isoforms of dopamine D2 receptors pp. 199-203

Alessandro Usiello, Ja-Hyun Baik, Françoise Rougé-Pont, Roberto Picetti, Andrée Dierich, Marianne LeMeur, Pier Vincenzo Piazza and Emiliana Borrelli

Regulation of repulsion versus adhesion by different splice forms of an Eph receptor pp. 203-206

Johan Holmberg, Diana L. Clarke and Jonas Frisén

Functional interaction of phytochrome B and cryptochrome 2 pp. 207-211

Paloma Más, Paul F. Devlin, Satchidananda Panda and Steve A. Kay

Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1 pp. 211-216

Robert Kleemann, Angelika Hausser, Georg Geiger, Ralf Mischke, Anke Burger-Kentischer, Oliver Flieger, Franz-Josef Johannes, Thierry Roger, Thierry Calandra, Aphrodite Kapurniotu, Matthias Grell, Doris Finkelmeier, Herwig Brunner and Jürgen Bernhagen

Cell-cycle-regulated DNA double-strand breaks in somatic hypermutation of immunoglobulin genes pp. 216-221

F. Nina Papavasiliou and David G. Schatz

PCNA connects DNA replication to epigenetic inheritance in yeast pp. 221-225

Zhiguo Zhang, Kei-ichi Shibahara and Bruce Stillman

A transcription reinitiation intermediate that is stabilized by activator pp. 225-229

Natalya Yudkovsky, Jeffrey A. Ranish and Steven Hahn

Why do we age? pp. 233-238

Thomas B. L. Kirkwood and Steven N. Austad

Oxidants, oxidative stress and the biology of ageing pp. 239-247

Toren Finkel and Nikki J. Holbrook

The age of cancer pp. 248-254

Ronald A. DePinho

Genetic pathways that regulate ageing in model organisms pp. 255-262

Leonard Guarente and Cynthia Kenyon

Lessons from human progeroid syndromes pp. 263-266

George M. Martin and Junko Oshima

The future of ageing pp. 267-269

Leonard Hayflick

Structural genomics — from cottage industry to industrial revolution pp. 273-274

Diane Gershon

2000, volume 408, articles 6808

Inquiry blames missed warnings for scale of Britain's BSE crisis pp. 3-4

Peter Aldhous

Were some CJD victims infected by vaccines? pp. 4-4

Karen Birmingham

Scientific turf war 'delayed potentially vital research' pp. 5-5

David Dickson

Kenyans protest at being left off AIDS patent pp. 6-6

Wachira Kigotho

Puffer fish joins genome stampede pp. 6-7

David Cyranoski and Paul Smaglik

US fusion community 'must end isolation', says panel pp. 7-7

Colin Macilwain

Whitehead enters into array deal pp. 7-7

Steve Nadis

Aquarium group fights 'cyanide fishing' pp. 8-8

Mark Schrope

... as scientists raise alarm over coral reefs pp. 9-9

Peter Pockley

Does size matter? pp. 13-15

Alexander Hellemans

Results may not fit well with current theories pp. 17-17

Gabby Dover

... but yeast prion offers clues about evolution pp. 17-18

Susan Lindquist

Genes should not be patentable, but if they are, we all have to do it pp. 017-017

Edgar Dutra Zanotto

In defence of Spanish R&D spending pp. 18-18

Ramón Marimon

Don't ignore the risk of vaccine contamination pp. 18-18

G. Lecatsas

Is Russian science recovering? pp. 19-20

Irina Dezhina and Loren Graham

A powerful leap from chaos pp. 21-22

Niall Ferguson

From pioneers to marketeers pp. 22-23

Rino Rappuoli

Secrets will out pp. 23-24

Simon Singh

Now you see it, now you don't pp. 24-25

Douglas R. O. Morrison

With a hammer and passion pp. 27-28

Philippe Janvier

Metamorphosis of a brain pp. 30-31

Yadin Dudai

Unravelling a tangled mind pp. 31-32

Bruce A. Yankner

What's in a name? pp. 33-33

Sandra Knapp

The stars my incarnation pp. 35-35

Robert A. Metzger

Small but mighty timekeepers pp. 37-38

André Adoutte

Surprising movements in solids pp. 38-39

Ulrich Gösele

Turning fields into grains pp. 39-41

Richard D. Thompson

An auroral signature decoded pp. 42-43

Patrick T. Newell

One cell, two fates pp. 43-45

Peter Carmeliet

Flipping a molecular switch pp. 45-46

Dan Feldheim

Regulation of the regulators pp. 46-47

Scott Stewart and Gerald R. Crabtree

Cosmic discord pp. 47-48

Craig J. Hogan

Global spread of microorganisms by ships pp. 49-50

Gregory M. Ruiz, Tonya K. Rawlings, Fred C. Dobbs, Lisa A. Drake, Timothy Mullady, Anwarul Huq and Rita R. Colwell

Single-walled 4 Å carbon nanotube arrays pp. 50-51

N. Wang, Z. K. Tang, G. D. Li and J. S. Chen

The smallest carbon nanotube pp. 50-50

Lu-Chang Qin, Xinluo Zhao, Kaori Hirahara, Yoshiyuki Miyamoto, Yoshinori Ando and Sumio Iijima

Hydrodynamic stimuli and the fish lateral line pp. 51-52

J. Engelmann, W. Hanke, J. Mogdans and H. Bleckmann

Telomere states and cell fates pp. 53-56

Elizabeth H. Blackburn

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function pp. 57-63

Julia Parrish-Novak, Stacey R. Dillon, Andrew Nelson, Angie Hammond, Cindy Sprecher, Jane A. Gross, Janet Johnston, Karen Madden, Wenfeng Xu, Jim West, Sara Schrader, Steve Burkhead, Mark Heipel, Cameron Brandt, Joseph L. Kuijper, Janet Kramer, Darrell Conklin, Scott R. Presnell, Jon Berry, Faith Shiota, Susan Bort, Kevin Hambly, Sherri Mudri, Chris Clegg, Margaret Moore, Francis J. Grant, Catherine Lofton-Day, Teresa Gilbert, Fenella Raymond, Andrew Ching, Lena Yao, Deb Smith, Philippa Webster, Theodore Whitmore, Mark Maurer, Kenneth Kaushansky, Rick D. Holly and Don Foster

A photorefractive organically modified silica glass with high optical gain pp. 64-67

Pavel Cheben, Francisco del Monte, Dennis J. Worsfold, Dave J. Carlsson, Chander P. Grover and John D. Mackenzie

A nanometre-scale electronic switch consisting of a metal cluster and redox-addressable groups pp. 67-69

David I. Gittins, Donald Bethell, David J. Schiffrin and Richard J. Nichols

Large disparity between gallium and antimony self-diffusion in gallium antimonide pp. 69-72

H. Bracht, S. P. Nicols, W. Walukiewicz, J. P. Silveira, F. Briones and E. E. Haller

Early onset and tropical forcing of 100,000-year Pleistocene glacial cycles pp. 72-75

Scott Rutherford and Steven D'Hondt

Accelerated hydration of the Earth's deep crust induced by stress perturbations pp. 75-78

Bjørn Jamtveit, Håkon Austrheim and Anders Malthe-Sørenssen

Elevated CO2 increases productivity and invasive species success in an arid ecosystem pp. 79-82

Stanley D. Smith, Travis E. Huxman, Stephen F. Zitzer, Therese N. Charlet, David C. Housman, James S. Coleman, Lynn K. Fenstermaker, Jeffrey R. Seemann and Robert S. Nowak

Evolutionary origins of vertebrate appendicular muscle pp. 82-86

C. Neyt, K. Jagla, C. Thisse, B. Thisse, L. Haines and P. D. Currie

Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA pp. 86-89

Amy E. Pasquinelli, Brenda J. Reinhart, Frank Slack, Mark Q. Martindale, Mitzi I. Kuroda, Betsy Maller, David C. Hayward, Eldon E. Ball, Bernard Degnan, Peter Müller, Jürg Spring, Ashok Srinivasan, Mark Fishman, John Finnerty, Joseph Corbo, Michael Levine, Patrick Leahy, Eric Davidson and Gary Ruvkun

Polarization of the anterior–posterior axis of C. elegans is a microtubule-directed process pp. 89-92

Matthew R. Wallenfang and Geraldine Seydoux

Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors pp. 92-96

Jun Yamashita, Hiroshi Itoh, Masanori Hirashima, Minetaro Ogawa, Satomi Nishikawa, Takami Yurugi, Makoto Naito, Kazuwa Nakao and Shin-Ichi Nishikawa

Bidirectional control of airway responsiveness by endogenous cannabinoids pp. 96-101

A. Calignano, I. Kátona, F. Désarnaud, A. Giuffrida, G. La Rana, K. Mackie, T. F. Freund and D. Piomelli

Identification of genes that modify ataxin-1-induced neurodegeneration pp. 101-106

Pedro Fernandez-Funez, Maria Laura Nino-Rosales, Beatrice de Gouyon, Wei-Chi She, James M. Luchak, Pedro Martinez, Enrique Turiegano, Jonathan Benito, Maria Capovilla, Pamela J. Skinner, Alanna McCall, Inmaculada Canal, Harry T. Orr, Huda Y. Zoghbi and Juan Botas

Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation pp. 106-111

Timothy A. McKinsey, Chun-Li Zhang, Jianrong Lu and Eric N. Olson

Structural basis for signal transduction by the Toll/interleukin-1 receptor domains pp. 111-115

Yingwu Xu, Xiao Tao, Baohe Shen, Tiffany Horng, Ruslan Medzhitov, James L. Manley and Liang Tong

Structural basis for the activation of 20S proteasomes by 11S regulators pp. 115-120

Frank G. Whitby, Eugene I. Masters, Larissa Kramer, J. Randolph Knowlton, Yi Yao, Ching C. Wang and Christopher P. Hill

Erratum: Production of gene-targeted sheep by nuclear transfer from cultured somatic cells pp. 120-120

K. J. McCreath, J. Howcroft, K. H. S. Campbell, A. Colman, A. E. Schnieke and A. J. Kind