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2014, volume 506, articles 7489

Is SIRT2 required for necroptosis? pp. E4-E6

Kim Newton, Joanne M. Hildebrand, Zhirong Shen, Diego Rodriguez, Silvia Alvarez-Diaz, Sean Petersen, Saumil Shah, Debra L. Dugger, Chunzi Huang, Johan Auwerx, Peter Vandenabeele, Douglas R. Green, Avi Ashkenazi, Vishva M. Dixit, William J. Kaiser, Andreas Strasser, Alexei Degterev and John Silke

Scientist-versus-activist debates mislead the public pp. 409-409

Simon L. Lewis

Vietnam on high alert over flu risk pp. 415-416

Declan Butler

Monkey brains wired to share pp. 416-417

Sara Reardon

São Paulo poised to join megatelescope pp. 417-418

Elizabeth Gibney

Einstein’s lost theory uncovered pp. 418-419

Davide Castelvecchi

Fish-kill method questioned pp. 419-420

Daniel Cressey

SOFIA irons out technical kinks pp. 420-421

Alexandra Witze

Crowd-sourcing: Strength in numbers pp. 422-423

Philip Ball

Science in court: Disease detectives pp. 424-426

Shaoni Bhattacharya

Earth science: Crystallography's journey to the deep Earth pp. 427-429

Thomas Duffy

Virology: Vanquishing HIV pp. 430-431

Sharon Lewin

Physics: Inside utter strangeness pp. 431-431

David Seery

Arts: Eclipse of power pp. 432-432

Jay M. Pasachoff and Naomi Pasachoff

Q&A: Melodic psychologist pp. 433-433

Jascha Hoffman

Expand fundraising by Brazil's institutes pp. 434-434

Tiago Campos Pereira

Stamina therapies: Time to call a halt pp. 434-434

Silvio Garattini, Giuseppe Remuzzi, Gianluca Vago and Alberto Zangrillo

Stamina therapies: Let the record stand pp. 434-434

Paolo Bianco, Elena Cattaneo, Michele De Luca and Luca Pani

Global fund needed for STEM education pp. 434-434

Fanuel Muindi and Moytrayee Guha

Drug discovery goes au naturel pp. 436-437

Clifton E. Barry

Optical trapping for space mirrors pp. 437-438

David McGloin

Tumours outside the mutation box pp. 438-439

Rogier Versteeg

Wind blown pp. 440-440

Andrew Mitchinson

The teamwork of precision pp. 440-441

Edmund G. Myers

Stressful genetics in Crohn's disease pp. 441-442

Arthur Kaser and Richard S. Blumberg

Involatile particles from rapid oxidation pp. 442-443

Gordon McFiggans

Epigenomic alterations define lethal CIMP-positive ependymomas of infancy pp. 445-450

S. C. Mack, H. Witt, R. M. Piro, L. Gu, S. Zuyderduyn, A. M. Stütz, X. Wang, M. Gallo, L. Garzia, K. Zayne, X. Zhang, V. Ramaswamy, N. Jäger, D. T. W. Jones, M. Sill, T. J. Pugh, M. Ryzhova, K. M. Wani, D. J. H. Shih, R. Head, M. Remke, S. D. Bailey, T. Zichner, C. C. Faria, M. Barszczyk, S. Stark, H. Seker-Cin, S. Hutter, P. Johann, S. Bender, V. Hovestadt, T. Tzaridis, A. M. Dubuc, P. A. Northcott, J. Peacock, K. C. Bertrand, S. Agnihotri, F. M. G. Cavalli, I. Clarke, K. Nethery-Brokx, C. L. Creasy, S. K. Verma, J. Koster, X. Wu, Y. Yao, T. Milde, P. Sin-Chan, J. Zuccaro, L. Lau, S. Pereira, P. Castelo-Branco, M. Hirst, M. A. Marra, S. S. Roberts, D. Fults, L. Massimi, Y. J. Cho, T. Van Meter, W. Grajkowska, B. Lach, A. E. Kulozik, A. von Deimling, O. Witt, S. W. Scherer, X. Fan, K. M. Muraszko, M. Kool, S. L. Pomeroy, N. Gupta, J. Phillips, A. Huang, U. Tabori, C. Hawkins, D. Malkin, P. N. Kongkham, W. A. Weiss, N. Jabado, J. T. Rutka, E. Bouffet, J. O. Korbel, M. Lupien, K. D. Aldape, G. D. Bader, R. Eils, P. Lichter, P. B. Dirks, S. M. Pfister, A. Korshunov and M. D. Taylor

C11orf95–RELA fusions drive oncogenic NF-κB signalling in ependymoma pp. 451-455

Matthew Parker, Kumarasamypet M. Mohankumar, Chandanamali Punchihewa, Ricardo Weinlich, James D. Dalton, Yongjin Li, Ryan Lee, Ruth G. Tatevossian, Timothy N. Phoenix, Radhika Thiruvenkatam, Elsie White, Bo Tang, Wilda Orisme, Kirti Gupta, Michael Rusch, Xiang Chen, Yuxin Li, Panduka Nagahawhatte, Erin Hedlund, David Finkelstein, Gang Wu, Sheila Shurtleff, John Easton, Kristy Boggs, Donald Yergeau, Bhavin Vadodaria, Heather L. Mulder, Jared Becksfort, Pankaj Gupta, Robert Huether, Jing Ma, Guangchun Song, Amar Gajjar, Thomas Merchant, Frederick Boop, Amy A. Smith, Li Ding, Charles Lu, Kerri Ochoa, David Zhao, Robert S. Fulton, Lucinda L. Fulton, Elaine R. Mardis, Richard K. Wilson, James R. Downing, Douglas R. Green, Jinghui Zhang, David W. Ellison and Richard J. Gilbertson

A Crohn’s disease variant in Atg16l1 enhances its degradation by caspase 3 pp. 456-462

Aditya Murthy, Yun Li, Ivan Peng, Mike Reichelt, Anand Kumar Katakam, Rajkumar Noubade, Merone Roose-Girma, Jason DeVoss, Lauri Diehl, Robert R. Graham and Menno van Lookeren Campagne

A single low-energy, iron-poor supernova as the source of metals in the star SMSS J031300.36−670839.3 pp. 463-466

S. C. Keller, M. S. Bessell, A. Frebel, A. R. Casey, M. Asplund, H. R. Jacobson, K. Lind, J. E. Norris, D. Yong, A. Heger, Z. Magic, G. S. Da Costa, B. P. Schmidt and P. Tisserand

High-precision measurement of the atomic mass of the electron pp. 467-470

S. Sturm, F. Köhler, J. Zatorski, A. Wagner, Z. Harman, G. Werth, W. Quint, C. H. Keitel and K. Blaum

Quantum droplets of electrons and holes pp. 471-475

A. E. Almand-Hunter, H. Li, S. T. Cundiff, M. Mootz, M. Kira and S. W. Koch

A large source of low-volatility secondary organic aerosol pp. 476-479

Mikael Ehn, Joel A. Thornton, Einhard Kleist, Mikko Sipilä, Heikki Junninen, Iida Pullinen, Monika Springer, Florian Rubach, Ralf Tillmann, Ben Lee, Felipe Lopez-Hilfiker, Stefanie Andres, Ismail-Hakki Acir, Matti Rissanen, Tuija Jokinen, Siegfried Schobesberger, Juha Kangasluoma, Jenni Kontkanen, Tuomo Nieminen, Theo Kurtén, Lasse B. Nielsen, Solvejg Jørgensen, Henrik G. Kjaergaard, Manjula Canagaratna, Miikka Dal Maso, Torsten Berndt, Tuukka Petäjä, Andreas Wahner, Veli-Matti Kerminen, Markku Kulmala, Douglas R. Worsnop, Jürgen Wildt and Thomas F. Mentel

Rapid remobilization of magmatic crystals kept in cold storage pp. 480-483

Kari M. Cooper and Adam J. R. Kent

Skin pigmentation provides evidence of convergent melanism in extinct marine reptiles pp. 484-488

Johan Lindgren, Peter Sjövall, Ryan M. Carney, Per Uvdal, Johan A. Gren, Gareth Dyke, Bo Pagh Schultz, Matthew D. Shawkey, Kenneth R. Barnes and Michael J. Polcyn

Sequential evolution of bacterial morphology by co-option of a developmental regulator pp. 489-493

Chao Jiang, Pamela J. B. Brown, Adrien Ducret and Yves V. Brun

Genetics of single-cell protein abundance variation in large yeast populations pp. 494-497

Frank W. Albert, Sebastian Treusch, Arthur H. Shockley, Joshua S. Bloom and Leonid Kruglyak

A discrete genetic locus confers xyloglucan metabolism in select human gut Bacteroidetes pp. 498-502

Johan Larsbrink, Theresa E. Rogers, Glyn R. Hemsworth, Lauren S. McKee, Alexandra S. Tauzin, Oliver Spadiut, Stefan Klinter, Nicholas A. Pudlo, Karthik Urs, Nicole M. Koropatkin, A. Louise Creagh, Charles A. Haynes, Amelia G. Kelly, Stefan Nilsson Cederholm, Gideon J. Davies, Eric C. Martens and Harry Brumer

Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity pp. 503-506

Kristin Westphalen, Galina A. Gusarova, Mohammad N. Islam, Manikandan Subramanian, Taylor S. Cohen, Alice S. Prince and Jahar Bhattacharya

A new metabolic cell-wall labelling method reveals peptidoglycan in Chlamydia trachomatis pp. 507-510

G. W. Liechti, E. Kuru, E. Hall, A. Kalinda, Y. V. Brun, M. VanNieuwenhze and A. T. Maurelli

Broadly permissive intestinal chromatin underlies lateral inhibition and cell plasticity pp. 511-515

Tae-Hee Kim, Fugen Li, Isabel Ferreiro-Neira, Li-Lun Ho, Annouck Luyten, Kodandaramireddy Nalapareddy, Henry Long, Michael Verzi and Ramesh A. Shivdasani

Retraction Note: The NAD-dependent deacetylase SIRT2 is required for programmed necrosis pp. 516-516

Nisha Narayan, In Hye Lee, Ronen Borenstein, Junhui Sun, Renee Wong, Guang Tong, Maria M. Fergusson, Jie Liu, Ilsa I. Rovira, Hwei-Ling Cheng, Guanghui Wang, Marjan Gucek, David Lombard, Fredrick W. Alt, Michael N. Sack, Elizabeth Murphy, Liu Cao and Toren Finkel

Erratum: Asymmetric synthesis from terminal alkenes by cascades of diboration and cross-coupling pp. 516-516

Scott N. Mlynarski, Christopher H. Schuster and James P. Morken

Addendum: Enterotypes of the human gut microbiome pp. 516-516

Manimozhiyan Arumugam, Jeroen Raes, Eric Pelletier, Denis Le Paslier, Takuji Yamada, Daniel R. Mende, Gabriel R. Fernandes, Julien Tap, Thomas Bruls, Jean-Michel Batto, Marcelo Bertalan, Natalia Borruel, Francesc Casellas, Leyden Fernandez, Laurent Gautier, Torben Hansen, Masahira Hattori, Tetsuya Hayashi, Michiel Kleerebezem, Ken Kurokawa, Marion Leclerc, Florence Levenez, Chaysavanh Manichanh, H. Bjørn Nielsen, Trine Nielsen, Nicolas Pons, Julie Poulain, Junjie Qin, Thomas Sicheritz-Ponten, Sebastian Tims, David Torrents, Edgardo Ugarte, Erwin G. Zoetendal, Jun Wang, Francisco Guarner, Oluf Pedersen, Willem M. de Vos, Søren Brunak, Joel Doré, MetaHIT Consortium, Jean Weissenbach, S. Dusko Ehrlich and Peer Bork

Computer science: Hacking into the cyberworld pp. 517-519

Bryn Nelson

No fury like a woman cold-called pp. 522-522

Jeremy R. Butler

2014, volume 506, articles 7488

WHO plans for neglected diseases are wrong pp. 267-267

Mary Moran

Fight against smog ramps up pp. 273-274

Jane Qiu

Missing galaxy mass found pp. 274-275

Eugenie Samuel Reich

China plunges into ocean research pp. 276-276

Jeff Tollefson

EU–Swiss research on shaky ground pp. 277-277

Quirin Schiermeier

Moon shots stuck on Earth pp. 278-278

Nicola Jones

Lone hunger striker spurs Nepal to action pp. 279-279

Smriti Mallapaty

Astronomy: Death of a comet pp. 281-283

Alexandra Witze

Science in court: Smart enough to die? pp. 284-286

Sara Reardon

Conservation: Nicaragua Canal could wreak environmental ruin pp. 287-289

Axel Meyer and Jorge A. Huete-Pérez

Policy: How to regulate faecal transplants pp. 290-291

Mark B. Smith, Colleen Kelly and Eric J. Alm

Nuclear energy: Meltdowns, redux pp. 292-293

Mark Peplow

Books in brief pp. 293-293

Barbara Kiser

Research and development: No matter, try again pp. 294-294

Anthony King

Move on to a carbon currency standard pp. 295-295

John R. Porter and Steve Wratten

Apply market forces to peer review pp. 295-295

Sascha Ott and Daniel Hebenstreit

Drug-resistant TB can be contained pp. 295-295

Erica Lessem and Salmaan Keshavjee

Sci-fi should not discredit vaccines pp. 295-295

Rachel Reddick

Lopsided stellar death pp. 298-299

J. Martin Laming

Take the brakes off for liver repair pp. 299-300

Andrew G. Cox and Wolfram Goessling

Persistence of leukaemic ancestors pp. 300-301

Nicola E. Potter and Mel Greaves

A promising advance in nuclear fusion pp. 302-303

Mark Herrmann

Protein binding cannot subdue a lively RNA pp. 303-304

Kathleen B. Hall

Genetic rejuvenation of old muscle pp. 304-305

Mo Li and Juan Carlos Izpisua Belmonte

The rise of oxygen in Earth’s early ocean and atmosphere pp. 307-315

Timothy W. Lyons, Christopher T. Reinhard and Noah J. Planavsky

Geriatric muscle stem cells switch reversible quiescence into senescence pp. 316-321

Pedro Sousa-Victor, Susana Gutarra, Laura García-Prat, Javier Rodriguez-Ubreva, Laura Ortet, Vanessa Ruiz-Bonilla, Mercè Jardí, Esteban Ballestar, Susana González, Antonio L. Serrano, Eusebio Perdiguero and Pura Muñoz-Cánoves

In situ identification of bipotent stem cells in the mammary gland pp. 322-327

Anne C. Rios, Nai Yang Fu, Geoffrey J. Lindeman and Jane E. Visvader

Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia pp. 328-333

Liran I. Shlush, Sasan Zandi, Amanda Mitchell, Weihsu Claire Chen, Joseph M. Brandwein, Vikas Gupta, James A. Kennedy, Aaron D. Schimmer, Andre C. Schuh, Karen W. Yee, Jessica L. McLeod, Monica Doedens, Jessie J. F. Medeiros, Rene Marke, Hyeoung Joon Kim, Kwon Lee, John D. McPherson, Thomas J. Hudson, The HALT Pan-Leukemia Gene Panel Consortium, Andrew M. K. Brown, Fouad Yousif, Quang M. Trinh, Lincoln D. Stein, Mark D. Minden, Jean C. Y. Wang and John E. Dick

Protein-guided RNA dynamics during early ribosome assembly pp. 334-338

Hajin Kim, Sanjaya C. Abeysirigunawarden, Ke Chen, Megan Mayerle, Kaushik Ragunathan, Zaida Luthey-Schulten, Taekjip Ha and Sarah A. Woodson

Asymmetries in core-collapse supernovae from maps of radioactive 44Ti in Cassiopeia A pp. 339-342

B. W. Grefenstette, F. A. Harrison, S. E. Boggs, S. P. Reynolds, C. L. Fryer, K. K. Madsen, D. R. Wik, A. Zoglauer, C. I. Ellinger, D. M. Alexander, H. An, D. Barret, F. E. Christensen, W. W. Craig, K. Forster, P. Giommi, C. J. Hailey, A. Hornstrup, V. M. Kaspi, T. Kitaguchi, J. E. Koglin, P. H. Mao, H. Miyasaka, K. Mori, M. Perri, M. J. Pivovaroff, S. Puccetti, V. Rana, D. Stern, N. J. Westergaard and W. W. Zhang

Fuel gain exceeding unity in an inertially confined fusion implosion pp. 343-348

O. A. Hurricane, D. A. Callahan, D. T. Casey, P. M. Celliers, C. Cerjan, E. L. Dewald, T. R. Dittrich, T. Döppner, D. E. Hinkel, L. F. Berzak Hopkins, J. L. Kline, S. Le Pape, T. Ma, A. G. MacPhee, J. L. Milovich, A. Pak, H.-S. Park, P. K. Patel, B. A. Remington, J. D. Salmonson, P. T. Springer and R. Tommasini

Exceptional ballistic transport in epitaxial graphene nanoribbons pp. 349-354

Jens Baringhaus, Ming Ruan, Frederik Edler, Antonio Tejeda, Muriel Sicot, Amina Taleb-Ibrahimi, An-Ping Li, Zhigang Jiang, Edward H. Conrad, Claire Berger, Christoph Tegenkamp and Walt A. de Heer

Prodigious degassing of a billion years of accumulated radiogenic helium at Yellowstone pp. 355-358

J. B. Lowenstern, W. C. Evans, D. Bergfeld and A. G. Hunt

Species coexistence and the dynamics of phenotypic evolution in adaptive radiation pp. 359-363

Joseph A. Tobias, Charlie K. Cornwallis, Elizabeth P. Derryberry, Santiago Claramunt, Robb T. Brumfield and Nathalie Seddon

Disease associations between honeybees and bumblebees as a threat to wild pollinators pp. 364-366

M. A. Fürst, D. P. McMahon, J. L. Osborne, R. J. Paxton and M. J. F. Brown

Unidirectional pulmonary airflow patterns in the savannah monitor lizard pp. 367-370

Emma R. Schachner, Robert L. Cieri, James P. Butler and C. G. Farmer

Landscape of genomic alterations in cervical carcinomas pp. 371-375

Akinyemi I. Ojesina, Lee Lichtenstein, Samuel S. Freeman, Chandra Sekhar Pedamallu, Ivan Imaz-Rosshandler, Trevor J. Pugh, Andrew D. Cherniack, Lauren Ambrogio, Kristian Cibulskis, Bjørn Bertelsen, Sandra Romero-Cordoba, Victor Treviño, Karla Vazquez-Santillan, Alberto Salido Guadarrama, Alexi A. Wright, Mara W. Rosenberg, Fujiko Duke, Bethany Kaplan, Rui Wang, Elizabeth Nickerson, Heather M. Walline, Michael S. Lawrence, Chip Stewart, Scott L. Carter, Aaron McKenna, Iram P. Rodriguez-Sanchez, Magali Espinosa-Castilla, Kathrine Woie, Line Bjorge, Elisabeth Wik, Mari K. Halle, Erling A. Hoivik, Camilla Krakstad, Nayeli Belem Gabiño, Gabriela Sofia Gómez-Macías, Lezmes D. Valdez-Chapa, María Lourdes Garza-Rodríguez, German Maytorena, Jorge Vazquez, Carlos Rodea, Adrian Cravioto, Maria L. Cortes, Heidi Greulich, Christopher P. Crum, Donna S. Neuberg, Alfredo Hidalgo-Miranda, Claudia Rangel Escareno, Lars A. Akslen, Thomas E. Carey, Olav K. Vintermyr, Stacey B. Gabriel, Hugo A. Barrera-Saldaña, Jorge Melendez-Zajgla, Gad Getz, Helga B. Salvesen and Matthew Meyerson

Genetics of rheumatoid arthritis contributes to biology and drug discovery pp. 376-381

Yukinori Okada, Di Wu, Gosia Trynka, Towfique Raj, Chikashi Terao, Katsunori Ikari, Yuta Kochi, Koichiro Ohmura, Akari Suzuki, Shinji Yoshida, Robert R. Graham, Arun Manoharan, Ward Ortmann, Tushar Bhangale, Joshua C. Denny, Robert J. Carroll, Anne E. Eyler, Jeffrey D. Greenberg, Joel M. Kremer, Dimitrios A. Pappas, Lei Jiang, Jian Yin, Lingying Ye, Ding-Feng Su, Jian Yang, Gang Xie, Ed Keystone, Harm-Jan Westra, Tõnu Esko, Andres Metspalu, Xuezhong Zhou, Namrata Gupta, Daniel Mirel, Eli A. Stahl, Dorothée Diogo, Jing Cui, Katherine Liao, Michael H. Guo, Keiko Myouzen, Takahisa Kawaguchi, Marieke J. H. Coenen, Piet L. C. M. van Riel, Mart A. F. J. van de Laar, Henk-Jan Guchelaar, Tom W. J. Huizinga, Philippe Dieudé, Xavier Mariette, S. Louis Bridges, Alexandra Zhernakova, Rene E. M. Toes, Paul P. Tak, Corinne Miceli-Richard, So-Young Bang, Hye-Soon Lee, Javier Martin, Miguel A. Gonzalez-Gay, Luis Rodriguez-Rodriguez, Solbritt Rantapää-Dahlqvist, Lisbeth Ärlestig, Hyon K. Choi, Yoichiro Kamatani, Pilar Galan, Mark Lathrop, Steve Eyre, John Bowes, Anne Barton, Niek de Vries, Larry W. Moreland, Lindsey A. Criswell, Elizabeth W. Karlson, Atsuo Taniguchi, Ryo Yamada, Michiaki Kubo, Jun S. Liu, Sang-Cheol Bae, Jane Worthington, Leonid Padyukov, Lars Klareskog, Peter K. Gregersen, Soumya Raychaudhuri, Barbara E. Stranger, Philip L. De Jager, Lude Franke, Peter M. Visscher, Matthew A. Brown, Hisashi Yamanaka, Tsuneyo Mimori, Atsushi Takahashi, Huji Xu, Timothy W. Behrens, Katherine A. Siminovitch, Shigeki Momohara, Fumihiko Matsuda, Kazuhiko Yamamoto and Robert M. Plenge

Selection and evaluation of clinically relevant AAV variants in a xenograft liver model pp. 382-386

Leszek Lisowski, Allison P. Dane, Kirk Chu, Yue Zhang, Sharon C. Cunningham, Elizabeth M. Wilson, Sean Nygaard, Markus Grompe, Ian E. Alexander and Mark A. Kay

Convergent evolution of a fused sexual cycle promotes the haploid lifestyle pp. 387-390

Racquel Kim Sherwood, Christine M. Scaduto, Sandra E. Torres and Richard J. Bennett

Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA pp. 391-395

Hideharu Hashimoto, June E. Pais, Xing Zhang, Lana Saleh, Zheng-Qing Fu, Nan Dai, Ivan R. Corrêa, Yu Zheng and Xiaodong Cheng

Correction: Corrigendum: Probabilistic cost estimates for climate change mitigation pp. 396-396

Joeri Rogelj, David L. McCollum, Andy Reisinger, Malte Meinshausen and Keywan Riahi

Correction: Corrigendum: Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome pp. 396-396

Shin Yoshimoto, Tze Mun Loo, Koji Atarashi, Hiroaki Kanda, Seidai Sato, Seiichi Oyadomari, Yoichiro Iwakura, Kenshiro Oshima, Hidetoshi Morita, Masahira Hattori, Kenya Honda, Yuichi Ishikawa, Eiji Hara and Naoko Ohtani

Correction: Corrigendum: DWARF 53 acts as a repressor of strigolactone signalling in rice pp. 396-396

Liang Jiang, Xue Liu, Guosheng Xiong, Huihui Liu, Fulu Chen, Lei Wang, Xiangbing Meng, Guifu Liu, Hong Yu, Yundong Yuan, Wei Yi, Lihua Zhao, Honglei Ma, Yuanzheng He, Zhongshan Wu, Karsten Melcher, Qian Qian, H. Eric Xu, Yonghong Wang and Jiayang Li

Interviews: En garde pp. 397-399

Karen Kaplan

Coffee in end times pp. 402-402

Alvaro Zinos-Amaro and Alex Shvartsman

2014, volume 506, articles 7487

Uncertainties in transpiration estimates pp. E1-E2

A. M. J. Coenders-Gerrits, R. J. van der Ent, T. A. Bogaard, L. Wang-Erlandsson, M. Hrachowitz and H. H. G. Savenije

Jasechko et al. reply pp. E2-E3

Scott Jasechko, Zachary D. Sharp, John J. Gibson, S. Jean Birks, Yi Yi and Peter J. Fawcett

Science at the sharp end of oppressive politics pp. 133-133

Andreas Kreiter

UK rolls out terror-attack plan pp. 139-140

Declan Butler

Iconic island study on its last legs pp. 140-141

Emma Marris

Ancient genome stirs ethics debate pp. 142-143

Ewen Callaway

NIH makes wary return to India pp. 143-144

Sara Reardon

Medicine gets up close and personal pp. 144-145

W. Wayt Gibbs

Medication: The smart-pill oversell pp. 146-148

Katherine Sharpe

Scientific method: Statistical errors pp. 150-152

Regina Nuzzo

Carbon sequestration: Managing forests in uncertain times pp. 153-155

Valentin Bellassen and Sebastiaan Luyssaert

Environmental sciences: The long goodbye pp. 156-157

Bob Bloomfield

Books in brief pp. 157-157

Barbara Kiser

Q&A: Acoustic archaeologist pp. 158-158

Jascha Hoffman

Biodiversity panel should play by rules pp. 159-159

Lars Opgenoorth, Stefan Hotes and Harold Mooney

Sexual violence rife on US campuses pp. 159-159

Stephen Shaffer

Scientists need leadership training pp. 159-159

Marina Kvaskoff and Stephanie D. McKay

Cuts threaten future of R&D in Portugal pp. 159-159

André Levy

Online repository for lab notebooks pp. 159-159

Shannon Bohle

Genetic roots of the first Americans pp. 162-163

Jennifer A. Raff and Deborah A. Bolnick

Cool start to hydrogen ionization pp. 163-164

Judd D. Bowman

A green illusion pp. 165-166

Kamel Soudani and Christophe François

History matters for a stirred superfluid pp. 166-167

Matthew J. Davis and Kristian Helmerson

Making marine protected areas work pp. 167-168

Benjamin S. Halpern

Eddy effects on biogeochemistry pp. 168-169

Amala Mahadevan

Cold dark matter heats up pp. 171-178

Andrew Pontzen and Fabio Governato

De novo mutations in schizophrenia implicate synaptic networks pp. 179-184

Menachem Fromer, Andrew J. Pocklington, David H. Kavanagh, Hywel J. Williams, Sarah Dwyer, Padhraig Gormley, Lyudmila Georgieva, Elliott Rees, Priit Palta, Douglas M. Ruderfer, Noa Carrera, Isla Humphreys, Jessica S. Johnson, Panos Roussos, Douglas D. Barker, Eric Banks, Vihra Milanova, Seth G. Grant, Eilis Hannon, Samuel A. Rose, Kimberly Chambert, Milind Mahajan, Edward M. Scolnick, Jennifer L. Moran, George Kirov, Aarno Palotie, Steven A. McCarroll, Peter Holmans, Pamela Sklar, Michael J. Owen, Shaun M. Purcell and Michael C. O’Donovan

A polygenic burden of rare disruptive mutations in schizophrenia pp. 185-190

Shaun M. Purcell, Jennifer L. Moran, Menachem Fromer, Douglas Ruderfer, Nadia Solovieff, Panos Roussos, Colm O’Dushlaine, Kimberly Chambert, Sarah E. Bergen, Anna Kähler, Laramie Duncan, Eli Stahl, Giulio Genovese, Esperanza Fernández, Mark O. Collins, Noboru H. Komiyama, Jyoti S. Choudhary, Patrik K. E. Magnusson, Eric Banks, Khalid Shakir, Kiran Garimella, Tim Fennell, Mark DePristo, Seth G. N. Grant, Stephen J. Haggarty, Stacey Gabriel, Edward M. Scolnick, Eric S. Lander, Christina M. Hultman, Patrick F. Sullivan, Steven A. McCarroll and Pamela Sklar

Molecular control of δ-opioid receptor signalling pp. 191-196

Gustavo Fenalti, Patrick M. Giguere, Vsevolod Katritch, Xi-Ping Huang, Aaron A. Thompson, Vadim Cherezov, Bryan L. Roth and Raymond C. Stevens

The observable signature of late heating of the Universe during cosmic reionization pp. 197-199

Anastasia Fialkov, Rennan Barkana and Eli Visbal

Hysteresis in a quantized superfluid ‘atomtronic’ circuit pp. 200-203

Stephen Eckel, Jeffrey G. Lee, Fred Jendrzejewski, Noel Murray, Charles W. Clark, Christopher J. Lobb, William D. Phillips, Mark Edwards and Gretchen K. Campbell

Quantum error correction in a solid-state hybrid spin register pp. 204-207

G. Waldherr, Yiqing Wang, S. Zaiser, M. Jamali, T. Schulte-Herbrüggen, H. Abe, T. Ohshima, J. Isoya, J. F. Du, P. Neumann and J. Wrachtrup

Mosaic two-lengthscale quasicrystals pp. 208-211

T. Dotera, T. Oshiro and P. Ziherl

A two-fold increase of carbon cycle sensitivity to tropical temperature variations pp. 212-215

Xuhui Wang, Shilong Piao, Philippe Ciais, Pierre Friedlingstein, Ranga B. Myneni, Peter Cox, Martin Heimann, John Miller, Shushi Peng, Tao Wang, Hui Yang and Anping Chen

Global conservation outcomes depend on marine protected areas with five key features pp. 216-220

Graham J. Edgar, Rick D. Stuart-Smith, Trevor J. Willis, Stuart Kininmonth, Susan C. Baker, Stuart Banks, Neville S. Barrett, Mikel A. Becerro, Anthony T. F. Bernard, Just Berkhout, Colin D. Buxton, Stuart J. Campbell, Antonia T. Cooper, Marlene Davey, Sophie C. Edgar, Günter Försterra, David E. Galván, Alejo J. Irigoyen, David J. Kushner, Rodrigo Moura, P. Ed Parnell, Nick T. Shears, German Soler, Elisabeth M. A. Strain and Russell J. Thomson

Amazon forests maintain consistent canopy structure and greenness during the dry season pp. 221-224

Douglas C. Morton, Jyoteshwar Nagol, Claudia C. Carabajal, Jacqueline Rosette, Michael Palace, Bruce D. Cook, Eric F. Vermote, David J. Harding and Peter R. J. North

The genome of a Late Pleistocene human from a Clovis burial site in western Montana pp. 225-229

Morten Rasmussen, Sarah L. Anzick, Michael R. Waters, Pontus Skoglund, Michael DeGiorgio, Thomas W. Stafford, Simon Rasmussen, Ida Moltke, Anders Albrechtsen, Shane M. Doyle, G. David Poznik, Valborg Gudmundsdottir, Rachita Yadav, Anna-Sapfo Malaspinas, Samuel Stockton White V, Morten E. Allentoft, Omar E. Cornejo, Kristiina Tambets, Anders Eriksson, Peter D. Heintzman, Monika Karmin, Thorfinn Sand Korneliussen, David J. Meltzer, Tracey L. Pierre, Jesper Stenderup, Lauri Saag, Vera M. Warmuth, Margarida C. Lopes, Ripan S. Malhi, Søren Brunak, Thomas Sicheritz-Ponten, Ian Barnes, Matthew Collins, Ludovic Orlando, Francois Balloux, Andrea Manica, Ramneek Gupta, Mait Metspalu, Carlos D. Bustamante, Mattias Jakobsson, Rasmus Nielsen and Eske Willerslev

Intranasal epidermal growth factor treatment rescues neonatal brain injury pp. 230-234

Joseph Scafidi, Timothy R. Hammond, Susanna Scafidi, Jonathan Ritter, Beata Jablonska, Maria Roncal, Klara Szigeti-Buck, Daniel Coman, Yuegao Huang, Robert J. McCarter, Fahmeed Hyder, Tamas L. Horvath and Vittorio Gallo

C/EBPα poises B cells for rapid reprogramming into induced pluripotent stem cells pp. 235-239

Bruno Di Stefano, Jose Luis Sardina, Chris van Oevelen, Samuel Collombet, Eric M. Kallin, Guillermo P. Vicent, Jun Lu, Denis Thieffry, Miguel Beato and Thomas Graf

Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts pp. 240-244

Aruna Kode, John S. Manavalan, Ioanna Mosialou, Govind Bhagat, Chozha V. Rathinam, Na Luo, Hossein Khiabanian, Albert Lee, Vundavalli V. Murty, Richard Friedman, Andrea Brum, David Park, Naomi Galili, Siddhartha Mukherjee, Julie Teruya-Feldstein, Azra Raza, Raul Rabadan, Ellin Berman and Stavroula Kousteni

RNA viruses can hijack vertebrate microRNAs to suppress innate immunity pp. 245-248

Derek W. Trobaugh, Christina L. Gardner, Chengqun Sun, Andrew D. Haddow, Eryu Wang, Elik Chapnik, Alexander Mildner, Scott C. Weaver, Kate D. Ryman and William B. Klimstra

RecA bundles mediate homology pairing between distant sisters during DNA break repair pp. 249-253

Christian Lesterlin, Graeme Ball, Lothar Schermelleh and David J. Sherratt

Correction: Corrigendum: IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis pp. 254-254

Weidong Zhu, Ichiro Shiojima, Yuzuru Ito, Zhi Li, Hiroyuki Ikeda, Masashi Yoshida, Atsuhiko T. Naito, Jun-ichiro Nishi, Hiroo Ueno, Akihiro Umezawa, Tohru Minamino, Toshio Nagai, Akira Kikuchi, Makoto Asashima and Issei Komuro

Erratum: Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells pp. 254-254

Yukihiro Furusawa, Yuuki Obata, Shinji Fukuda, Takaho A. Endo, Gaku Nakato, Daisuke Takahashi, Yumiko Nakanishi, Chikako Uetake, Keiko Kato, Tamotsu Kato, Masumi Takahashi, Noriko N. Fukuda, Shinnosuke Murakami, Eiji Miyauchi, Shingo Hino, Koji Atarashi, Satoshi Onawa, Yumiko Fujimura, Trevor Lockett, Julie M. Clarke, David L. Topping, Masaru Tomita, Shohei Hori, Osamu Ohara, Tatsuya Morita, Haruhiko Koseki, Jun Kikuchi, Kenya Honda, Koji Hase and Hiroshi Ohno

Correction: Corrigendum: The architecture of Tetrahymena telomerase holoenzyme pp. 254-254

Jiansen Jiang, Edward J. Miracco, Kyungah Hong, Barbara Eckert, Henry Chan, Darian D. Cash, Bosun Min, Z. Hong Zhou, Kathleen Collins and Juli Feigon

Web design: Webcraft 101 pp. 255-257

Roberta Kwok

Self-taught soft skills pp. 257-257

Alexandra Lucs

Howard loves Polly pp. 260-260

Martin Hayes

2014, volume 506, articles 7486

China must protect high-quality arable land pp. 7-7

Xiangbin Kong

Faulty forensic science under fire pp. 13-14

Sara Reardon

UK visa problems worry scientists pp. 14-15

Daniel Cressey

Computer sharing loses momentum pp. 16-17

Nicola Jones

Elsevier opens its papers to text-mining pp. 17-17

Richard Van Noorden

Grapevine gene bank under threat pp. 18-18

Declan Butler

Phosphorene excites materials scientists pp. 19-19

Eugenie Samuel Reich

Winter Olympics: Downhill forecast pp. 20-22

Lauren Morello

Biomedicine: The changing face of primate research pp. 24-26

Alison Abbott

Climate economics: Make supply chains climate-smart pp. 27-29

Anders Levermann

Evolution: The human puzzle pp. 30-31

Henry Gee

Books in brief pp. 31-31

Barbara Kiser

Geology: Bedrock of China pp. 32-32

Xu Xing

Q&A: The sound hunter pp. 33-33

Jascha Hoffman

Medical data: the choice to opt out pp. 34-34

Geraint Lewis

Medical data: widen use in research pp. 34-34

Jeremy Farrar

Planck team replies to data 'anomalies' pp. 34-34

Jan Tauber

Carbon dioxide storage is secure pp. 34-34

Vivian Scott

John Cornforth (1917–2013) pp. 35-35

Jim Hanson

A talented genus pp. 38-39

Marcel Jaspars and Greg Challis

Interference identifies immune modulators pp. 39-40

Lars Zender

Drought and fire change sink to source pp. 41-42

Jennifer K. Balch

Oiling the wheels of autoimmunity pp. 42-43

Mitchell Kronenberg and Wendy L. Havran

Quarks are not ambidextrous pp. 43-44

William J. Marciano

Plant diversity rooted in pathogens pp. 44-45

Helene C. Muller-Landau

Fifty thousand years of Arctic vegetation and megafaunal diet pp. 47-51

Eske Willerslev, John Davison, Mari Moora, Martin Zobel, Eric Coissac, Mary E. Edwards, Eline D. Lorenzen, Mette Vestergård, Galina Gussarova, James Haile, Joseph Craine, Ludovic Gielly, Sanne Boessenkool, Laura S. Epp, Peter B. Pearman, Rachid Cheddadi, David Murray, Kari Anne Bråthen, Nigel Yoccoz, Heather Binney, Corinne Cruaud, Patrick Wincker, Tomasz Goslar, Inger Greve Alsos, Eva Bellemain, Anne Krag Brysting, Reidar Elven, Jørn Henrik Sønstebø, Julian Murton, Andrei Sher, Morten Rasmussen, Regin Rønn, Tobias Mourier, Alan Cooper, Jeremy Austin, Per Möller, Duane Froese, Grant Zazula, François Pompanon, Delphine Rioux, Vincent Niderkorn, Alexei Tikhonov, Grigoriy Savvinov, Richard G. Roberts, Ross D. E. MacPhee, M. Thomas P. Gilbert, Kurt H. Kjær, Ludovic Orlando, Christian Brochmann and Pierre Taberlet

In vivo discovery of immunotherapy targets in the tumour microenvironment pp. 52-57

Penghui Zhou, Donald R. Shaffer, Diana A. Alvarez Arias, Yukoh Nakazaki, Wouter Pos, Alexis J. Torres, Viviana Cremasco, Stephanie K. Dougan, Glenn S. Cowley, Kutlu Elpek, Jennifer Brogdon, John Lamb, Shannon J. Turley, Hidde L. Ploegh, David E. Root, J. Christopher Love, Glenn Dranoff, Nir Hacohen, Harvey Cantor and Kai W. Wucherpfennig

An environmental bacterial taxon with a large and distinct metabolic repertoire pp. 58-62

Micheal C. Wilson, Tetsushi Mori, Christian Rückert, Agustinus R. Uria, Maximilian J. Helf, Kentaro Takada, Christine Gernert, Ursula A. E. Steffens, Nina Heycke, Susanne Schmitt, Christian Rinke, Eric J. N. Helfrich, Alexander O. Brachmann, Cristian Gurgui, Toshiyuki Wakimoto, Matthias Kracht, Max Crüsemann, Ute Hentschel, Ikuro Abe, Shigeki Matsunaga, Jörn Kalinowski, Haruko Takeyama and Jörn Piel

A cosmic web filament revealed in Lyman-α emission around a luminous high-redshift quasar pp. 63-66

Sebastiano Cantalupo, Fabrizio Arrigoni-Battaia, J. Xavier Prochaska, Joseph F. Hennawi and Piero Madau

An optical lattice clock with accuracy and stability at the 10−18 level pp. 71-75

B. J. Bloom, T. L. Nicholson, J. R. Williams, S. L. Campbell, M. Bishof, X. Zhang, W. Zhang, S. L. Bromley and J. Ye

Drought sensitivity of Amazonian carbon balance revealed by atmospheric measurements pp. 76-80

L. V. Gatti, M. Gloor, J. B. Miller, C. E. Doughty, Y. Malhi, L. G. Domingues, L. S. Basso, A. Martinewski, C. S. C. Correia, V. F. Borges, S. Freitas, R. Braz, L. O. Anderson, H. Rocha, J. Grace, O. L. Phillips and J. Lloyd

Convective forcing of mercury and ozone in the Arctic boundary layer induced by leads in sea ice pp. 81-84

Christopher W. Moore, Daniel Obrist, Alexandra Steffen, Ralf M. Staebler, Thomas A. Douglas, Andreas Richter and Son V. Nghiem

Pathogens and insect herbivores drive rainforest plant diversity and composition pp. 85-88

Robert Bagchi, Rachel E. Gallery, Sofia Gripenberg, Sarah J. Gurr, Lakshmi Narayan, Claire E. Addis, Robert P. Freckleton and Owen T. Lewis

Three keys to the radiation of angiosperms into freezing environments pp. 89-92

Amy E. Zanne, David C. Tank, William K. Cornwell, Jonathan M. Eastman, Stephen A. Smith, Richard G. FitzJohn, Daniel J. McGlinn, Brian C. O’Meara, Angela T. Moles, Peter B. Reich, Dana L. Royer, Douglas E. Soltis, Peter F. Stevens, Mark Westoby, Ian J. Wright, Lonnie Aarssen, Robert I. Bertin, Andre Calaminus, Rafaël Govaerts, Frank Hemmings, Michelle R. Leishman, Jacek Oleksyn, Pamela S. Soltis, Nathan G. Swenson, Laura Warman and Jeremy M. Beaulieu

Modelling the effects of subjective and objective decision making in scientific peer review pp. 93-96

In-Uck Park, Mike Peacey and Marcus R. Munafò

Structure of the SecY channel during initiation of protein translocation pp. 102-106

Eunyong Park, Jean-François Ménétret, James C. Gumbart, Steven J. Ludtke, Weikai Li, Andrew Whynot, Tom A. Rapoport and Christopher W. Akey

Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion pp. 107-110

Marko Gogala, Thomas Becker, Birgitta Beatrix, Jean-Paul Armache, Clara Barrio-Garcia, Otto Berninghausen and Roland Beckmann

Aprataxin resolves adenylated RNA–DNA junctions to maintain genome integrity pp. 111-115

Percy Tumbale, Jessica S. Williams, Matthew J. Schellenberg, Thomas A. Kunkel and R. Scott Williams

Crystal structures of the Lsm complex bound to the 3′ end sequence of U6 small nuclear RNA pp. 116-120

Lijun Zhou, Jing Hang, Yulin Zhou, Ruixue Wan, Guifeng Lu, Ping Yin, Chuangye Yan and Yigong Shi

Telecommuting: No place like home pp. 121-123

Karen Kaplan

Vessels for destruction pp. 126-126

A. G. Carpenter