Rational design of α-helical tandem repeat proteins with closed architectures

Lindsey Doyle, Jazmine Hallinan, Jill Bolduc, Fabio Parmeggiani, David Baker, Barry L. Stoddard and Philip Bradley ()
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Lindsey Doyle: Fred Hutchinson Cancer Research Center
Jazmine Hallinan: Fred Hutchinson Cancer Research Center
Jill Bolduc: Fred Hutchinson Cancer Research Center
Fabio Parmeggiani: University of Washington
David Baker: University of Washington
Barry L. Stoddard: Fred Hutchinson Cancer Research Center
Philip Bradley: Fred Hutchinson Cancer Research Center

Nature, 2015, vol. 528, issue 7583, 585-588

Abstract: The development and validation of computational methods for geometry-guided de novo design of tandem repeat protein architectures.

Date: 2015
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DOI: 10.1038/nature16191

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