FGF signalling regulates bone growth through autophagy

Laura Cinque, Alison Forrester, Rosa Bartolomeo, Maria Svelto, Rossella Venditti, Sandro Montefusco, Elena Polishchuk, Edoardo Nusco, Antonio Rossi, Diego L. Medina, Roman Polishchuk, Maria Antonietta De Matteis and Carmine Settembre ()
Additional contact information
Laura Cinque: Telethon Institute of Genetics and Medicine (TIGEM)
Alison Forrester: Telethon Institute of Genetics and Medicine (TIGEM)
Rosa Bartolomeo: Telethon Institute of Genetics and Medicine (TIGEM)
Maria Svelto: Telethon Institute of Genetics and Medicine (TIGEM)
Rossella Venditti: Telethon Institute of Genetics and Medicine (TIGEM)
Sandro Montefusco: Telethon Institute of Genetics and Medicine (TIGEM)
Elena Polishchuk: Telethon Institute of Genetics and Medicine (TIGEM)
Edoardo Nusco: Telethon Institute of Genetics and Medicine (TIGEM)
Antonio Rossi: Biochemistry Unit, University of Pavia
Diego L. Medina: Telethon Institute of Genetics and Medicine (TIGEM)
Roman Polishchuk: Telethon Institute of Genetics and Medicine (TIGEM)
Maria Antonietta De Matteis: Telethon Institute of Genetics and Medicine (TIGEM)
Carmine Settembre: Telethon Institute of Genetics and Medicine (TIGEM)

Nature, 2015, vol. 528, issue 7581, 272-275

Abstract: During postnatal development in mice, the growth factor FGF18 induces autophagy in the chondrocyte cells of the growth plate to regulate the secretion of type II collagen, a process required for bone growth.

Date: 2015
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DOI: 10.1038/nature16063

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