Signal integration by Ca2+ regulates intestinal stem-cell activity

Hansong Deng, Akos A. Gerencser and Heinrich Jasper ()
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Hansong Deng: The Buck Institute for Research on Aging, 8001 Redwood Boulevard
Akos A. Gerencser: The Buck Institute for Research on Aging, 8001 Redwood Boulevard
Heinrich Jasper: The Buck Institute for Research on Aging, 8001 Redwood Boulevard

Nature, 2015, vol. 528, issue 7581, 212-217

Abstract: Drosophila intestinal stem cells (ISCs) respond to changes in diet, particularly L-glutamate levels, by modulating Ca2+ signalling to adapt their proliferation rate; furthermore, Ca2+ is shown to be central to the response of ISCs to a wide range of dietary and stress stimuli.

Date: 2015
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DOI: 10.1038/nature16170

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