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2020, volume 586, articles 7831

Author Correction: An atlas of dynamic chromatin landscapes in mouse fetal development pp. E31-E31

David U. Gorkin, Iros Barozzi, Yuan Zhao, Yanxiao Zhang, Hui Huang, Ah Young Lee, Bin Li, Joshua Chiou, Andre Wildberg, Bo Ding, Bo Zhang, Mengchi Wang, J. Seth Strattan, Jean M. Davidson, Yunjiang Qiu, Veena Afzal, Jennifer A. Akiyama, Ingrid Plajzer-Frick, Catherine S. Novak, Momoe Kato, Tyler H. Garvin, Quan T. Pham, Anne N. Harrington, Brandon J. Mannion, Elizabeth A. Lee, Yoko Fukuda-Yuzawa, Yupeng He, Sebastian Preissl, Sora Chee, Jee Yun Han, Brian A. Williams, Diane Trout, Henry Amrhein, Hongbo Yang, J. Michael Cherry, Wei Wang, Kyle Gaulton, Joseph R. Ecker, Yin Shen, Diane E. Dickel, Axel Visel, Len A. Pennacchio and Bing Ren

Author Correction: Soil carbon loss by experimental warming in a tropical forest pp. E32-E32

Andrew T. Nottingham, Patrick Meir, Esther Velasquez and Benjamin L. Turner

Ethiopia, Somalia and Kenya face devastating drought pp. 645-645

Chris Funk

Dozens to be deliberately infected with coronavirus in UK ‘human challenge’ trials pp. 651-652

Ewen Callaway

Why COVID outbreaks look set to worsen this winter pp. 653-653

Smriti Mallapaty

Scientists strongly back Joe Biden for US president in Nature poll pp. 654-654

Giuliana Viglione

Brexit’s back: the five issues that will shape science pp. 656-657

Holly Else and Elizabeth Gibney

Can lab-grown brains become conscious? pp. 658-661

Sara Reardon

These bizarre ancient species are rewriting animal evolution pp. 662-665

Traci Watson

How precision medicine paved the way to the first cystic fibrosis drug pp. 667-668

Heidi Ledford

The discredited doctor hailed by the anti-vaccine movement pp. 668-669

Saad B. Omer

Joseph H. Connell (1923–2020) pp. 670-670

Jane Lubchenco and Wayne P. Sousa

Europe’s Green Deal offshores environmental damage to other nations pp. 671-673

Richard Fuchs, Calum Brown and Mark Rounsevell

Europe’s public-health systems gear up for future epidemics pp. 674-674

Giuseppe Ippolito

Myanmar amber fossils: a legal as well as ethical quagmire pp. 674-674

Paul M. Barrett and Zerina Johanson

Satellite megaclusters could fox night-time migrations pp. 674-674

Chris Lintott and Paul Lintott

Uruguay: slashing funds is no way to thank scientists for COVID success pp. 674-674

Daniel Prieto

Eye of a skull reveals details of cometary materials pp. 675-676

Erik Asphaug

Demystifying the D-loop during DNA recombination pp. 677-678

Upasana Roy and Eric C. Greene

Fresh evidence challenges the consensus view of active sites in an industrial catalyst pp. 678-679

Bert M. Weckhuysen

Prioritizing where to restore Earth’s ecosystems pp. 680-681

Simon Ferrier

Strategic vision for improving human health at The Forefront of Genomics pp. 683-692

Eric D. Green, Chris Gunter, Leslie G. Biesecker, Valentina Francesco, Carla L. Easter, Elise A. Feingold, Adam L. Felsenfeld, David J. Kaufman, Elaine A. Ostrander, William J. Pavan, Adam M. Phillippy, Anastasia L. Wise, Jyoti Gupta Dayal, Britny J. Kish, Allison Mandich, Christopher R. Wellington, Kris A. Wetterstrand, Sarah A. Bates, Darryl Leja, Susan Vasquez, William A. Gahl, Bettie J. Graham, Daniel L. Kastner, Paul Liu, Laura Lyman Rodriguez, Benjamin D. Solomon, Vence L. Bonham, Lawrence C. Brody, Carolyn M. Hutter and Teri A. Manolio

Diverse polarization angle swings from a repeating fast radio burst source pp. 693-696

R. Luo, B. J. Wang, Y. P. Men, C. F. Zhang, J. C. Jiang, H. Xu, W. Y. Wang, K. J. Lee, J. L. Han, B. Zhang, R. N. Caballero, M. Z. Chen, X. L. Chen, H. Q. Gan, Y. J. Guo, L. F. Hao, Y. X. Huang, P. Jiang, H. Li, J. Li, Z. X. Li, J. T. Luo, J. Pan, X. Pei, L. Qian, J. H. Sun, M. Wang, N. Wang, Z. G. Wen, R. X. Xu, Y. H. Xu, J. Yan, W. M. Yan, D. J. Yu, J. P. Yuan, S. B. Zhang and Y. Zhu

The Philae lander reveals low-strength primitive ice inside cometary boulders pp. 697-701

Laurence O’Rourke, Philip Heinisch, Jürgen Blum, Sonia Fornasier, Gianrico Filacchione, Hong Hoang, Mauro Ciarniello, Andrea Raponi, Bastian Gundlach, Rafael Andrés Blasco, Björn Grieger, Karl-Heinz Glassmeier, Michael Küppers, Alessandra Rotundi, Olivier Groussin, Dominique Bockelée-Morvan, Hans-Ulrich Auster, Nilda Oklay, Gerhard Paar, Maria del Pilar Caballo Perucha, Gabor Kovacs, Laurent Jorda, Jean-Baptiste Vincent, Fabrizio Capaccioni, Nicolas Biver, Joel Wm. Parker, Cecilia Tubiana and Holger Sierks

High-throughput calculations of magnetic topological materials pp. 702-707

Yuanfeng Xu, Luis Elcoro, Zhi-Da Song, Benjamin J. Wieder, M. G. Vergniory, Nicolas Regnault, Yulin Chen, Claudia Felser and B. Andrei Bernevig

Efficient epoxidation over dinuclear sites in titanium silicalite-1 pp. 708-713

Christopher P. Gordon, Hauke Engler, Amadeus Samuel Tragl, Milivoj Plodinec, Thomas Lunkenbein, Albrecht Berkessel, Joaquim Henrique Teles, Andrei-Nicolae Parvulescu and Christophe Copéret

Metal-free photoinduced C(sp3)–H borylation of alkanes pp. 714-719

Chao Shu, Adam Noble and Varinder K. Aggarwal

Large Chinese land carbon sink estimated from atmospheric carbon dioxide data pp. 720-723

Jing Wang, Liang Feng, Paul I. Palmer, Yi Liu, Shuangxi Fang, Hartmut Bösch, Christopher W. O’Dell, Xiaoping Tang, Dongxu Yang, Lixin Liu and ChaoZong Xia

Global priority areas for ecosystem restoration pp. 724-729

Bernardo B. N. Strassburg, Alvaro Iribarrem, Hawthorne L. Beyer, Carlos Leandro Cordeiro, Renato Crouzeilles, Catarina C. Jakovac, André Braga Junqueira, Eduardo Lacerda, Agnieszka E. Latawiec, Andrew Balmford, Thomas M. Brooks, Stuart H. M. Butchart, Robin L. Chazdon, Karl-Heinz Erb, Pedro Brancalion, Graeme Buchanan, David Cooper, Sandra Díaz, Paul F. Donald, Valerie Kapos, David Leclère, Lera Miles, Michael Obersteiner, Christoph Plutzar, Carlos Alberto M. Scaramuzza, Fabio R. Scarano and Piero Visconti

Stimulus-specific hypothalamic encoding of a persistent defensive state pp. 730-734

Ann Kennedy, Prabhat S. Kunwar, Ling-yun Li, Stefanos Stagkourakis, Daniel A. Wagenaar and David J. Anderson

The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease pp. 735-740

Ji-Yeun Hur, Georgia R. Frost, Xianzhong Wu, Christina Crump, Si Jia Pan, Eitan Wong, Marilia Barros, Thomas Li, Pengju Nie, Yujia Zhai, Jen Chyong Wang, Julia Tcw, Lei Guo, Andrew McKenzie, Chen Ming, Xianxiao Zhou, Minghui Wang, Yotam Sagi, Alan E. Renton, Bianca T. Esposito, Yong Kim, Katherine R. Sadleir, Ivy Trinh, Robert A. Rissman, Robert Vassar, Bin Zhang, Douglas S. Johnson, Eliezer Masliah, Paul Greengard, Alison Goate and Yue-Ming Li

High-depth African genomes inform human migration and health pp. 741-748

Ananyo Choudhury, Shaun Aron, Laura R. Botigué, Dhriti Sengupta, Gerrit Botha, Taoufik Bensellak, Gordon Wells, Judit Kumuthini, Daniel Shriner, Yasmina J. Fakim, Anisah W. Ghoorah, Eileen Dareng, Trust Odia, Oluwadamilare Falola, Ezekiel Adebiyi, Scott Hazelhurst, Gaston Mazandu, Oscar A. Nyangiri, Mamana Mbiyavanga, Alia Benkahla, Samar K. Kassim, Nicola Mulder, Sally N. Adebamowo, Emile R. Chimusa, Donna Muzny, Ginger Metcalf, Richard A. Gibbs, Charles Rotimi, Michèle Ramsay, Adebowale A. Adeyemo, Zané Lombard and Neil A. Hanchard

Exome sequencing and characterization of 49,960 individuals in the UK Biobank pp. 749-756

Cristopher V. Van Hout, Ioanna Tachmazidou, Joshua D. Backman, Joshua D. Hoffman, Daren Liu, Ashutosh K. Pandey, Claudia Gonzaga-Jauregui, Shareef Khalid, Bin Ye, Nilanjana Banerjee, Alexander H. Li, Colm O’Dushlaine, Anthony Marcketta, Jeffrey Staples, Claudia Schurmann, Alicia Hawes, Evan Maxwell, Leland Barnard, Alexander Lopez, John Penn, Lukas Habegger, Andrew L. Blumenfeld, Xiaodong Bai, Sean O’Keeffe, Ashish Yadav, Kavita Praveen, Marcus Jones, William J. Salerno, Wendy K. Chung, Ida Surakka, Cristen J. Willer, Kristian Hveem, Joseph B. Leader, David J. Carey, David H. Ledbetter, Lon Cardon, George D. Yancopoulos, Aris Economides, Giovanni Coppola, Alan R. Shuldiner, Suganthi Balasubramanian, Michael Cantor, Matthew R. Nelson, John Whittaker, Jeffrey G. Reid, Jonathan Marchini, John D. Overton, Robert A. Scott, Gonçalo R. Abecasis, Laura Yerges-Armstrong and Aris Baras

Evidence for 28 genetic disorders discovered by combining healthcare and research data pp. 757-762

Joanna Kaplanis, Kaitlin E. Samocha, Laurens Wiel, Zhancheng Zhang, Kevin J. Arvai, Ruth Y. Eberhardt, Giuseppe Gallone, Stefan H. Lelieveld, Hilary C. Martin, Jeremy F. McRae, Patrick J. Short, Rebecca I. Torene, Elke Boer, Petr Danecek, Eugene J. Gardner, Ni Huang, Jenny Lord, Iñigo Martincorena, Rolph Pfundt, Margot R. F. Reijnders, Alison Yeung, Helger G. Yntema, Lisenka E. L. M. Vissers, Jane Juusola, Caroline F. Wright, Han G. Brunner, Helen V. Firth, David R. FitzPatrick, Jeffrey C. Barrett, Matthew E. Hurles, Christian Gilissen and Kyle Retterer

Inherited causes of clonal haematopoiesis in 97,691 whole genomes pp. 763-768

Alexander G. Bick, Joshua S. Weinstock, Satish K. Nandakumar, Charles P. Fulco, Erik L. Bao, Seyedeh M. Zekavat, Mindy D. Szeto, Xiaotian Liao, Matthew J. Leventhal, Joseph Nasser, Kyle Chang, Cecelia Laurie, Bala Bharathi Burugula, Christopher J. Gibson, Abhishek Niroula, Amy E. Lin, Margaret A. Taub, Francois Aguet, Kristin Ardlie, Braxton D. Mitchell, Kathleen C. Barnes, Arden Moscati, Myriam Fornage, Susan Redline, Bruce M. Psaty, Edwin K. Silverman, Scott T. Weiss, Nicholette D. Palmer, Ramachandran S. Vasan, Esteban G. Burchard, Sharon L. R. Kardia, Jiang He, Robert C. Kaplan, Nicholas L. Smith, Donna K. Arnett, David A. Schwartz, Adolfo Correa, Mariza Andrade, Xiuqing Guo, Barbara A. Konkle, Brian Custer, Juan M. Peralta, Hongsheng Gui, Deborah A. Meyers, Stephen T. McGarvey, Ida Yii- Der Chen, M. Benjamin Shoemaker, Patricia A. Peyser, Jai G. Broome, Stephanie M. Gogarten, Fei Fei Wang, Quenna Wong, May E. Montasser, Michelle Daya, Eimear E. Kenny, Kari E. North, Lenore J. Launer, Brian E. Cade, Joshua C. Bis, Michael H. Cho, Jessica Lasky-Su, Donald W. Bowden, L. Adrienne Cupples, Angel C. Y. Mak, Lewis C. Becker, Jennifer A. Smith, Tanika N. Kelly, Stella Aslibekyan, Susan R. Heckbert, Hemant K. Tiwari, Ivana V. Yang, John A. Heit, Steven A. Lubitz, Jill M. Johnsen, Joanne E. Curran, Sally E. Wenzel, Daniel E. Weeks, Dabeeru C. Rao, Dawood Darbar, Jee-Young Moon, Russell P. Tracy, Erin J. Buth, Nicholas Rafaels, Ruth J. F. Loos, Peter Durda, Yongmei Liu, Lifang Hou, Jiwon Lee, Priyadarshini Kachroo, Barry I. Freedman, Daniel Levy, Lawrence F. Bielak, James E. Hixson, James S. Floyd, Eric A. Whitsel, Patrick T. Ellinor, Marguerite R. Irvin, Tasha E. Fingerlin, Laura M. Raffield, Sebastian M. Armasu, Marsha M. Wheeler, Ester C. Sabino, John Blangero, L. Keoki Williams, Bruce D. Levy, Wayne Huey-Herng Sheu, Dan M. Roden, Eric Boerwinkle, JoAnn E. Manson, Rasika A. Mathias, Pinkal Desai, Kent D. Taylor, Andrew D. Johnson, Paul L. Auer, Charles Kooperberg, Cathy C. Laurie, Thomas W. Blackwell, Albert V. Smith, Hongyu Zhao, Ethan Lange, Leslie Lange, Stephen S. Rich, Jerome I. Rotter, James G. Wilson, Paul Scheet, Jacob O. Kitzman, Eric S. Lander, Jesse M. Engreitz, Benjamin L. Ebert, Alexander P. Reiner, Siddhartha Jaiswal, Gonçalo Abecasis, Vijay G. Sankaran, Sekar Kathiresan and Pradeep Natarajan

Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells pp. 769-775

Erik L. Bao, Satish K. Nandakumar, Xiaotian Liao, Alexander G. Bick, Juha Karjalainen, Marcin Tabaka, Olga I. Gan, Aki S. Havulinna, Tuomo T. J. Kiiskinen, Caleb A. Lareau, Aitzkoa L. Lapuente Portilla, Bo Li, Connor Emdin, Veryan Codd, Christopher P. Nelson, Christopher J. Walker, Claire Churchhouse, Albert Chapelle, Daryl E. Klein, Björn Nilsson, Peter W. F. Wilson, Kelly Cho, Saiju Pyarajan, J. Michael Gaziano, Nilesh J. Samani, Aviv Regev, Aarno Palotie, Benjamin M. Neale, John E. Dick, Pradeep Natarajan, Christopher J. O’Donnell, Mark J. Daly, Michael Milyavsky, Sekar Kathiresan and Vijay G. Sankaran

Infection of dogs with SARS-CoV-2 pp. 776-778

Thomas H. C. Sit, Christopher J. Brackman, Sin Ming Ip, Karina W. S. Tam, Pierra Y. T. Law, Esther M. W. To, Veronica Y. T. Yu, Leslie D. Sims, Dominic N. C. Tsang, Daniel K. W. Chu, Ranawaka A. P. M. Perera, Leo L. M. Poon and Malik Peiris

Immune receptor inhibition through enforced phosphatase recruitment pp. 779-784

Ricardo A. Fernandes, Leon Su, Yoko Nishiga, Junming Ren, Aladdin M. Bhuiyan, Ning Cheng, Calvin J. Kuo, Lora K. Picton, Shozo Ohtsuki, Robbie G. Majzner, Skyler P. Rietberg, Crystal L. Mackall, Qian Yin, Lestat R. Ali, Xinbo Yang, Christina S. Savvides, Julien Sage, Michael Dougan and K. Christopher Garcia

Capillary cell-type specialization in the alveolus pp. 785-789

Astrid Gillich, Fan Zhang, Colleen G. Farmer, Kyle J. Travaglini, Serena Y. Tan, Mingxia Gu, Bin Zhou, Jeffrey A. Feinstein, Mark A. Krasnow and Ross J. Metzger

Serine restriction alters sphingolipid diversity to constrain tumour growth pp. 790-795

Thangaselvam Muthusamy, Thekla Cordes, Michal K. Handzlik, Le You, Esther W. Lim, Jivani Gengatharan, Antonio F. M. Pinto, Mehmet G. Badur, Matthew J. Kolar, Martina Wallace, Alan Saghatelian and Christian M. Metallo

In-cell architecture of the nuclear pore and snapshots of its turnover pp. 796-800

Matteo Allegretti, Christian E. Zimmerli, Vasileios Rantos, Florian Wilfling, Paolo Ronchi, Herman K. H. Fung, Chia-Wei Lee, Wim Hagen, Beata Turoňová, Kai Karius, Mandy Börmel, Xiaojie Zhang, Christoph W. Müller, Yannick Schwab, Julia Mahamid, Boris Pfander, Jan Kosinski and Martin Beck

Mechanism of strand exchange from RecA–DNA synaptic and D-loop structures pp. 801-806

Haijuan Yang, Chun Zhou, Ankita Dhar and Nikola P. Pavletich

Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms pp. 807-811

Christian B. Billesbølle, Caleigh M. Azumaya, Rachael C. Kretsch, Alexander S. Powers, Shane Gonen, Simon Schneider, Tara Arvedson, Ron O. Dror, Yifan Cheng and Aashish Manglik

How LGBT+ scientists would like to be included and welcomed in STEM workplaces pp. 813-816

Kendall Powell, Ruth Terry and Sophia Chen

The tale of a mouse-lab mastermind pp. 818-818

Chris Woolston

2020, volume 586, articles 7830

Methods matter in repeating ocean acidification studies pp. E20-E24

Philip L. Munday, Danielle L. Dixson, Megan J. Welch, Douglas P. Chivers, Paolo Domenici, Martin Grosell, Rachael M. Heuer, Geoffrey P. Jones, Mark I. McCormick, Mark Meekan, Göran E. Nilsson, Timothy Ravasi and Sue-Ann Watson

Reply to: Methods matter in repeating ocean acidification studies pp. E25-E27

Timothy D. Clark, Graham D. Raby, Dominique G. Roche, Sandra A. Binning, Ben Speers-Roesch, Fredrik Jutfelt and Josefin Sundin

Author Correction: The honeycomb maze provides a novel test to study hippocampal-dependent spatial navigation pp. E28-E28

Ruth A. Wood, Marius Bauza, Julija Krupic, Stephen Burton, Andrea Delekate, Dennis Chan and John O’Keefe

Publisher Correction: Heat and carbon coupling reveals ocean warming due to circulation changes pp. E29-E29

Ben Bronselaer and Laure Zanna

Publisher Correction: A protein assembly mediates Xist localization and gene silencing pp. E30-E30

Amy Pandya-Jones, Yolanda Markaki, Jacques Serizay, Tsotne Chitiashvili, Walter R. Mancia Leon, Andrey Damianov, Constantinos Chronis, Bernadett Papp, Chun-Kan Chen, Robin McKee, Xiao-Jun Wang, Anthony Chau, Shan Sabri, Heinrich Leonhardt, Sika Zheng, Mitchell Guttman, Douglas. L. Black and Kathrin Plath

Antimicrobial resistance pp. S49-S49

Sarah O’Meara

Why big pharma has abandoned antibiotics pp. S50-S52

Benjamin Plackett

The art of infection prevention pp. S53-S54

Kristina Campbell

How researchers are revamping antimicrobial drugs pp. S55-S56

Neil Savage

Drug discovery needs to change pp. S57-S57

James K. Martin

Research round-up: Antimicrobial resistance pp. S58-S59

Elizabeth Svoboda

How China is getting its farmers to kick their antibiotics habit pp. S60-S62

Kevin Schoenmakers

Aquaculture’s role in propagating antimicrobial resistance must be addressed pp. S63-S63

Natalie Healey

Don’t ignore another disease threat pp. S64-S64

David Wallinga

COVID-19 vaccines: time to talk about the uncertainties pp. 475-475

Kanta Subbarao

Latin America’s embrace of an unproven COVID treatment is hindering drug trials pp. 481-482

Emiliano Rodríguez Mega

How China could be carbon neutral by mid-century pp. 482-483

Smriti Mallapaty

NASA ‘fist bumps’ an asteroid to reveal Solar System’s secrets pp. 484-485

Alexandra Witze

The unsung heroes of the Nobel-winning hepatitis C discovery pp. 485-485

Heidi Ledford

What it’s really like to do science amid COVID-19 pp. 486-487

Quirin Schiermeier, Holly Else, Emiliano Rodríguez Mega, T.V. Padma and Nisha Gaind

How obesity could create problems for a COVID vaccine pp. 488-489

Heidi Ledford

How to get more women and people of colour into graduate school — and keep them there pp. 491-492

Sibrina N. Collins

The code-breakers who led the rise of computing pp. 492-493

Andrew Robinson

Georgina Mace (1953–2020) pp. 495-495

Nathalie Pettorelli

Protect the Antarctic Peninsula — before it’s too late pp. 496-499

Carolyn J. Hogg, Mary-Anne Lea, Marga Gual Soler, Váleri N. Vasquez, Ana Payo-Payo, Marissa L. Parrott, M. Mercedes Santos, Justine Shaw and Cassandra M. Brooks

Non-animal-derived antibodies: pharma companies respond pp. 500-500

Matt Truppo, George Yancopoulos, Andrew J. Murphy, Allan Bradley, Larry Green and Ivo Lorenz

Hunger in Africa: get the costing right pp. 500-500

Zia Mehrabi

Commercial antibodies: alternative grading for research pp. 500-500

Seth Blackshaw and Heng Zhu

Question hubris in nations’ COVID-19 responses pp. 500-500

Adrian P. Mundt

All eyes on a hurdle race for a SARS-CoV-2 vaccine pp. 501-502

Christian Gaebler and Michel C. Nussenzweig

Diabolical ironclad beetles inspire tougher joints for engineering applications pp. 502-504

Po-Yu Chen

Seeds of cancer in normal skin pp. 504-506

Inigo Martincorena

Melt mapped inside Earth’s mantle pp. 506-507

Laura Cobden

Animal models for COVID-19 pp. 509-515

César Muñoz-Fontela, William E. Dowling, Simon G. P. Funnell, Pierre-S. Gsell, A. Ximena Riveros-Balta, Randy A. Albrecht, Hanne Andersen, Ralph S. Baric, Miles W. Carroll, Marco Cavaleri, Chuan Qin, Ian Crozier, Kai Dallmeier, Leon Waal, Emmie Wit, Leen Delang, Erik Dohm, W. Paul Duprex, Darryl Falzarano, Courtney L. Finch, Matthew B. Frieman, Barney S. Graham, Lisa E. Gralinski, Kate Guilfoyle, Bart L. Haagmans, Geraldine A. Hamilton, Amy L. Hartman, Sander Herfst, Suzanne J. F. Kaptein, William B. Klimstra, Ivana Knezevic, Philip R. Krause, Jens H. Kuhn, Roger Grand, Mark G. Lewis, Wen-Chun Liu, Pauline Maisonnasse, Anita K. McElroy, Vincent Munster, Nadia Oreshkova, Angela L. Rasmussen, Joana Rocha-Pereira, Barry Rockx, Estefanía Rodríguez, Thomas F. Rogers, Francisco J. Salguero, Michael Schotsaert, Koert J. Stittelaar, Hendrik Jan Thibaut, Chien-Te Tseng, Júlia Vergara-Alert, Martin Beer, Trevor Brasel, Jasper F. W. Chan, Adolfo García-Sastre, Johan Neyts, Stanley Perlman, Douglas S. Reed, Juergen A. Richt, Chad J. Roy, Joaquim Segalés, Seshadri S. Vasan, Ana María Henao-Restrepo and Dan H. Barouch

SARS-CoV-2 vaccines in development pp. 516-527

Florian Krammer

Stellar clustering shapes the architecture of planetary systems pp. 528-532

Andrew J. Winter, J. M. Diederik Kruijssen, Steven N. Longmore and Mélanie Chevance

Integrated optical multi-ion quantum logic pp. 533-537

Karan K. Mehta, Chi Zhang, Maciej Malinowski, Thanh-Long Nguyen, Martin Stadler and Jonathan P. Home

Integrated multi-wavelength control of an ion qubit pp. 538-542

R. J. Niffenegger, J. Stuart, C. Sorace-Agaskar, D. Kharas, S. Bramhavar, C. D. Bruzewicz, W. Loh, R. T. Maxson, R. McConnell, D. Reens, G. N. West, J. M. Sage and J. Chiaverini

Toughening mechanisms of the elytra of the diabolical ironclad beetle pp. 543-548

Jesus Rivera, Maryam Sadat Hosseini, David Restrepo, Satoshi Murata, Drago Vasile, Dilworth Y. Parkinson, Harold S. Barnard, Atsushi Arakaki, Pablo Zavattieri and David Kisailus

Filling metal–organic framework mesopores with TiO2 for CO2 photoreduction pp. 549-554

Zhuo Jiang, Xiaohui Xu, Yanhang Ma, Hae Sung Cho, Deng Ding, Chao Wang, Jie Wu, Peter Oleynikov, Mei Jia, Jun Cheng, Yi Zhou, Osamu Terasaki, Tianyou Peng, Ling Zan and Hexiang Deng

Seismic evidence for partial melt below tectonic plates pp. 555-559

Eric Debayle, Thomas Bodin, Stéphanie Durand and Yanick Ricard

A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures pp. 560-566

Kenneth H. Dinnon, Sarah R. Leist, Alexandra Schäfer, Caitlin E. Edwards, David R. Martinez, Stephanie A. Montgomery, Ande West, Boyd L. Yount, Yixuan J. Hou, Lily E. Adams, Kendra L. Gully, Ariane J. Brown, Emily Huang, Matthew D. Bryant, Ingrid C. Choong, Jeffrey S. Glenn, Lisa E. Gralinski, Timothy P. Sheahan and Ralph S. Baric

SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness pp. 567-571

Kizzmekia S. Corbett, Darin K. Edwards, Sarah R. Leist, Olubukola M. Abiona, Seyhan Boyoglu-Barnum, Rebecca A. Gillespie, Sunny Himansu, Alexandra Schäfer, Cynthia T. Ziwawo, Anthony T. DiPiazza, Kenneth H. Dinnon, Sayda M. Elbashir, Christine A. Shaw, Angela Woods, Ethan J. Fritch, David R. Martinez, Kevin W. Bock, Mahnaz Minai, Bianca M. Nagata, Geoffrey B. Hutchinson, Kai Wu, Carole Henry, Kapil Bahl, Dario Garcia-Dominguez, LingZhi Ma, Isabella Renzi, Wing-Pui Kong, Stephen D. Schmidt, Lingshu Wang, Yi Zhang, Emily Phung, Lauren A. Chang, Rebecca J. Loomis, Nedim Emil Altaras, Elisabeth Narayanan, Mihir Metkar, Vlad Presnyak, Cuiping Liu, Mark K. Louder, Wei Shi, Kwanyee Leung, Eun Sung Yang, Ande West, Kendra L. Gully, Laura J. Stevens, Nianshuang Wang, Daniel Wrapp, Nicole A. Doria-Rose, Guillaume Stewart-Jones, Hamilton Bennett, Gabriela S. Alvarado, Martha C. Nason, Tracy J. Ruckwardt, Jason S. McLellan, Mark R. Denison, James D. Chappell, Ian N. Moore, Kaitlyn M. Morabito, John R. Mascola, Ralph S. Baric, Andrea Carfi and Barney S. Graham

A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity pp. 572-577

Jingyun Yang, Wei Wang, Zimin Chen, Shuaiyao Lu, Fanli Yang, Zhenfei Bi, Linlin Bao, Fei Mo, Xue Li, Yong Huang, Weiqi Hong, Yun Yang, Yuan Zhao, Fei Ye, Sheng Lin, Wei Deng, Hua Chen, Hong Lei, Ziqi Zhang, Min Luo, Hong Gao, Yue Zheng, Yanqiu Gong, Xiaohua Jiang, Yanfeng Xu, Qi Lv, Dan Li, Manni Wang, Fengdi Li, Shunyi Wang, Guanpeng Wang, Pin Yu, Yajin Qu, Li Yang, Hongxin Deng, Aiping Tong, Jiong Li, Zhenling Wang, Jinliang Yang, Guobo Shen, Zhiwei Zhao, Yuhua Li, Jingwen Luo, Hongqi Liu, Wenhai Yu, Mengli Yang, Jingwen Xu, Junbin Wang, Haiyan Li, Haixuan Wang, Dexuan Kuang, Panpan Lin, Zhengtao Hu, Wei Guo, Wei Cheng, Yanlin He, Xiangrong Song, Chong Chen, Zhihong Xue, Shaohua Yao, Lu Chen, Xuelei Ma, Siyuan Chen, Maling Gou, Weijin Huang, Youchun Wang, Changfa Fan, Zhixin Tian, Ming Shi, Fu-Sheng Wang, Lunzhi Dai, Min Wu, Gen Li, Guangyu Wang, Yong Peng, Zhiyong Qian, Canhua Huang, Johnson Yiu-Nam Lau, Zhenglin Yang, Yuquan Wei, Xiaobo Cen, Xiaozhong Peng, Chuan Qin, Kang Zhang, Guangwen Lu and Xiawei Wei

ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques pp. 578-582

Neeltje van Doremalen, Teresa Lambe, Alexandra Spencer, Sandra Belij-Rammerstorfer, Jyothi N. Purushotham, Julia R. Port, Victoria A. Avanzato, Trenton Bushmaker, Amy Flaxman, Marta Ulaszewska, Friederike Feldmann, Elizabeth R. Allen, Hannah Sharpe, Jonathan Schulz, Myndi Holbrook, Atsushi Okumura, Kimberly Meade-White, Lizzette Pérez-Pérez, Nick J. Edwards, Daniel Wright, Cameron Bissett, Ciaran Gilbride, Brandi N. Williamson, Rebecca Rosenke, Dan Long, Alka Ishwarbhai, Reshma Kailath, Louisa Rose, Susan Morris, Claire Powers, Jamie Lovaglio, Patrick W. Hanley, Dana Scott, Greg Saturday, Emmie de Wit, Sarah C. Gilbert and Vincent J. Munster

Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques pp. 583-588

Noe B. Mercado, Roland Zahn, Frank Wegmann, Carolin Loos, Abishek Chandrashekar, Jingyou Yu, Jinyan Liu, Lauren Peter, Katherine McMahan, Lisa H. Tostanoski, Xuan He, David R. Martinez, Lucy Rutten, Rinke Bos, Danielle Manen, Jort Vellinga, Jerome Custers, Johannes P. Langedijk, Ted Kwaks, Mark J. G. Bakkers, David Zuijdgeest, Sietske K. Rosendahl Huber, Caroline Atyeo, Stephanie Fischinger, John S. Burke, Jared Feldman, Blake M. Hauser, Timothy M. Caradonna, Esther A. Bondzie, Gabriel Dagotto, Makda S. Gebre, Emily Hoffman, Catherine Jacob-Dolan, Marinela Kirilova, Zhenfeng Li, Zijin Lin, Shant H. Mahrokhian, Lori F. Maxfield, Felix Nampanya, Ramya Nityanandam, Joseph P. Nkolola, Shivani Patel, John D. Ventura, Kaylee Verrington, Huahua Wan, Laurent Pessaint, Alex Ry, Kelvin Blade, Amanda Strasbaugh, Mehtap Cabus, Renita Brown, Anthony Cook, Serge Zouantchangadou, Elyse Teow, Hanne Andersen, Mark G. Lewis, Yongfei Cai, Bing Chen, Aaron G. Schmidt, R. Keith Reeves, Ralph S. Baric, Douglas A. Lauffenburger, Galit Alter, Paul Stoffels, Mathai Mammen, Johan Hoof, Hanneke Schuitemaker and Dan H. Barouch

Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults pp. 589-593

Mark J. Mulligan, Kirsten E. Lyke, Nicholas Kitchin, Judith Absalon, Alejandra Gurtman, Stephen Lockhart, Kathleen Neuzil, Vanessa Raabe, Ruth Bailey, Kena A. Swanson, Ping Li, Kenneth Koury, Warren Kalina, David Cooper, Camila Fontes-Garfias, Pei-Yong Shi, Özlem Türeci, Kristin R. Tompkins, Edward E. Walsh, Robert Frenck, Ann R. Falsey, Philip R. Dormitzer, William C. Gruber, Uğur Şahin and Kathrin U. Jansen

COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses pp. 594-599

Ugur Sahin, Alexander Muik, Evelyna Derhovanessian, Isabel Vogler, Lena M. Kranz, Mathias Vormehr, Alina Baum, Kristen Pascal, Jasmin Quandt, Daniel Maurus, Sebastian Brachtendorf, Verena Lörks, Julian Sikorski, Rolf Hilker, Dirk Becker, Ann-Kathrin Eller, Jan Grützner, Carsten Boesler, Corinna Rosenbaum, Marie-Cristine Kühnle, Ulrich Luxemburger, Alexandra Kemmer-Brück, David Langer, Martin Bexon, Stefanie Bolte, Katalin Karikó, Tania Palanche, Boris Fischer, Armin Schultz, Pei-Yong Shi, Camila Fontes-Garfias, John L. Perez, Kena A. Swanson, Jakob Loschko, Ingrid L. Scully, Mark Cutler, Warren Kalina, Christos A. Kyratsous, David Cooper, Philip R. Dormitzer, Kathrin U. Jansen and Özlem Türeci

The genomic landscapes of individual melanocytes from human skin pp. 600-605

Jessica Tang, Eleanor Fewings, Darwin Chang, Hanlin Zeng, Shanshan Liu, Aparna Jorapur, Rachel L. Belote, Andrew S. McNeal, Tuyet M. Tan, Iwei Yeh, Sarah T. Arron, Robert L. Judson-Torres, Boris C. Bastian and A. Hunter Shain

Immune-evasive human islet-like organoids ameliorate diabetes pp. 606-611

Eiji Yoshihara, Carolyn O’Connor, Emanuel Gasser, Zong Wei, Tae Gyu Oh, Tiffany W. Tseng, Dan Wang, Fritz Cayabyab, Yang Dai, Ruth T. Yu, Christopher Liddle, Annette R. Atkins, Michael Downes and Ronald M. Evans

A single-cell transcriptome atlas of marsupial embryogenesis and X inactivation pp. 612-617

Shantha K. Mahadevaiah, Mahesh N. Sangrithi, Takayuki Hirota and James M. A. Turner

Regulation of the MLH1–MLH3 endonuclease in meiosis pp. 618-622

Elda Cannavo, Aurore Sanchez, Roopesh Anand, Lepakshi Ranjha, Jannik Hugener, Céline Adam, Ananya Acharya, Nicolas Weyland, Xavier Aran-Guiu, Jean-Baptiste Charbonnier, Eva R. Hoffmann, Valérie Borde, Joao Matos and Petr Cejka

PCNA activates the MutLγ endonuclease to promote meiotic crossing over pp. 623-627

Dhananjaya S. Kulkarni, Shannon N. Owens, Masayoshi Honda, Masaru Ito, Ye Yang, Mary W. Corrigan, Lan Chen, Aric L. Quan and Neil Hunter

Wear your mask, but think about deaf students pp. 629-630

Olivier Pourret and Elodie Saillet

How managing a chronic illness gave me skills that would strengthen my PhD pp. 630-630

Olivia Favor

Probing fine-scale connections in the brain pp. 631-633

Esther Landhuis

The scientist-gardener who is harnessing tobacco’s power to heal pp. 636-636

Virginia Gewin

2020, volume 586, articles 7829

Headache pp. S1-S1

Richard Hodson

A visual guide to migraine headaches pp. S2-S3

Neil Savage

A new generation of headache drugs pp. S4-S6

Marcus Woo

A richer view of aura pp. S7-S9

Liam Drew

Research round-up: headache pp. S10-S11

Anthony King

The puzzle of migraine chronification pp. S12-S14

Neil Savage

Transparency and reproducibility in artificial intelligence pp. E14-E16

Benjamin Haibe-Kains, George Alexandru Adam, Ahmed Hosny, Farnoosh Khodakarami, Levi Waldron, Bo Wang, Christopher McIntosh, Anna Goldenberg, Anshul Kundaje, Casey S. Greene, Tamara Broderick, Michael M. Hoffman, Jeffrey T. Leek, Keegan Korthauer, Wolfgang Huber, Alvis Brazma, Joelle Pineau, Robert Tibshirani, Trevor Hastie, John P. A. Ioannidis, John Quackenbush and Hugo J. W. L. Aerts

Cluster headaches cause years of needless pain pp. S15-S15

Ashley S. Hattle

Closing the gender gap in migraine research pp. S16-S17

Michael Eisenstein

Reply to: Transparency and reproducibility in artificial intelligence pp. E17-E18

Scott Mayer McKinney, Alan Karthikesalingam, Daniel Tse, Christopher J. Kelly, Yun Liu, Greg S. Corrado and Shravya Shetty

Treating headache to save sight pp. S18-S18

Julianna Photopoulos

The unique demands of childhood migraine pp. S19-S21

Emily Sohn

Addendum: International evaluation of an AI system for breast cancer screening pp. E19-E19

Scott Mayer McKinney, Marcin Sieniek, Varun Godbole, Jonathan Godwin, Natasha Antropova, Hutan Ashrafian, Trevor Back, Mary Chesus, Greg S. Corrado, Ara Darzi, Mozziyar Etemadi, Florencia Garcia-Vicente, Fiona J. Gilbert, Mark Halling-Brown, Demis Hassabis, Sunny Jansen, Alan Karthikesalingam, Christopher J. Kelly, Dominic King, Joseph R. Ledsam, David Melnick, Hormuz Mostofi, Lily Peng, Joshua Jay Reicher, Bernardino Romera-Paredes, Richard Sidebottom, Mustafa Suleyman, Daniel Tse, Kenneth C. Young, Jeffrey Fauw and Shravya Shetty

Tired of science being ignored? Get political pp. 337-337

Mary T. Bassett

What China’s speedy COVID vaccine deployment means for the pandemic pp. 343-344

David Cyranoski

Last chance for WIMPs: physicists launch all-out hunt for dark-matter candidate pp. 344-345

Elizabeth Gibney

Pioneers of revolutionary CRISPR gene editing win chemistry Nobel pp. 346-347

Heidi Ledford and Ewen Callaway

Physicists who unravelled mysteries of black holes win Nobel prize pp. 347-348

Elizabeth Gibney and Davide Castelvecchi

Virologists who discovered hepatitis C win medicine Nobel pp. 348-348

Ewen Callaway and Heidi Ledford

First room-temperature superconductor excites — and baffles — scientists pp. 349-349

Davide Castelvecchi

Contact tracing Trump’s travels would be ‘massive but feasible’ pp. 350-350

Nidhi Subbaraman

How anti-ageing drugs could boost COVID vaccines in older people pp. 352-354

Cassandra Willyard

Ruth Bader Ginsburg (1933–2020) pp. 355-355

Sarah Franklin

Berni Alder (1925–2020) pp. 356-356

David Ceperley

Research integrity: nine ways to move from talk to walk pp. 358-360

Niels Mejlgaard, Lex M. Bouter, George Gaskell, Panagiotis Kavouras, Nick Allum, Anna-Kathrine Bendtsen, Costas A. Charitidis, Nik Claesen, Kris Dierickx, Anna Domaradzka, Andrea Reyes Elizondo, Nicole Foeger, Maura Hiney, Wolfgang Kaltenbrunner, Krishma Labib, Ana Marušić, Mads P. Sørensen, Tine Ravn, Rea Ščepanović, Joeri K. Tijdink and Giuseppe A. Veltri

Key ingredient of galaxy formation measured pp. 361-362

Chris L. Carilli

Bacteria sting viral invaders pp. 363-364

Justin Jenson and Zhijian J. Chen

Brain-inspired computing boosted by new concept of completeness pp. 364-366

Oliver Rhodes

Brain’s immune cells put the brakes on neurons pp. 366-367

Thomas Pfeiffer and David Attwell

H i 21-centimetre emission from an ensemble of galaxies at an average redshift of one pp. 369-372

Aditya Chowdhury, Nissim Kanekar, Jayaram N. Chengalur, Shiv Sethi and K. S. Dwarakanath

RETRACTED ARTICLE: Room-temperature superconductivity in a carbonaceous sulfur hydride pp. 373-377

Elliot Snider, Nathan Dasenbrock-Gammon, Raymond McBride, Mathew Debessai, Hiranya Vindana, Kevin Vencatasamy, Keith V. Lawler, Ashkan Salamat and Ranga P. Dias

A system hierarchy for brain-inspired computing pp. 378-384

Youhui Zhang, Peng Qu, Yu Ji, Weihao Zhang, Guangrong Gao, Guanrui Wang, Sen Song, Guoqi Li, Wenguang Chen, Weimin Zheng, Feng Chen, Jing Pei, Rong Zhao, Mingguo Zhao and Luping Shi

Efficient and stable blue quantum dot light-emitting diode pp. 385-389

Taehyung Kim, Kwang-Hee Kim, Sungwoo Kim, Seon-Myeong Choi, Hyosook Jang, Hong-Kyu Seo, Heejae Lee, Dae-Young Chung and Eunjoo Jang

Surface coordination layer passivates oxidation of copper pp. 390-394

Jian Peng, Bili Chen, Zhichang Wang, Jing Guo, Binghui Wu, Shuqiang Hao, Qinghua Zhang, Lin Gu, Qin Zhou, Zhi Liu, Shuqin Hong, Sifan You, Ang Fu, Zaifa Shi, Hao Xie, Duanyun Cao, Chang-Jian Lin, Gang Fu, Lan-Sun Zheng, Ying Jiang and Nanfeng Zheng

Building cratonic keels in Precambrian plate tectonics pp. 395-401

A. L. Perchuk, T. V. Gerya, V. S. Zakharov and W. L. Griffin

Environmental drivers of megafauna and hominin extinction in Southeast Asia pp. 402-406

Julien Louys and Patrick Roberts

Amygdala inhibitory neurons as loci for translation in emotional memories pp. 407-411

Prerana Shrestha, Zhe Shan, Maggie Mamcarz, Karen San Agustin Ruiz, Adam T. Zerihoun, Chien-Yu Juan, Pedro M. Herrero-Vidal, Jerry Pelletier, Nathaniel Heintz and Eric Klann

eIF2α controls memory consolidation via excitatory and somatostatin neurons pp. 412-416

Vijendra Sharma, Rapita Sood, Abdessattar Khlaifia, Mohammad Javad Eslamizade, Tzu-Yu Hung, Danning Lou, Azam Asgarihafshejani, Maya Lalzar, Stephen J. Kiniry, Matthew P. Stokes, Noah Cohen, Alissa J. Nelson, Kathryn Abell, Anthony P. Possemato, Shunit Gal-Ben-Ari, Vinh T. Truong, Peng Wang, Adonis Yiannakas, Fatemeh Saffarzadeh, A. Claudio Cuello, Karim Nader, Randal J. Kaufman, Mauro Costa-Mattioli, Pavel V. Baranov, Albert Quintana, Elisenda Sanz, Arkady Khoutorsky, Jean-Claude Lacaille, Kobi Rosenblum and Nahum Sonenberg

Negative feedback control of neuronal activity by microglia pp. 417-423

Ana Badimon, Hayley J. Strasburger, Pinar Ayata, Xinhong Chen, Aditya Nair, Ako Ikegami, Philip Hwang, Andrew T. Chan, Steven M. Graves, Joseph O. Uweru, Carola Ledderose, Munir Gunes Kutlu, Michael A. Wheeler, Anat Kahan, Masago Ishikawa, Ying-Chih Wang, Yong-Hwee E. Loh, Jean X. Jiang, D. James Surmeier, Simon C. Robson, Wolfgang G. Junger, Robert Sebra, Erin S. Calipari, Paul J. Kenny, Ukpong B. Eyo, Marco Colonna, Francisco J. Quintana, Hiroaki Wake, Viviana Gradinaru and Anne Schaefer

Relatives of rubella virus in diverse mammals pp. 424-428

Andrew J. Bennett, Adrian C. Paskey, Arnt Ebinger, Florian Pfaff, Grit Priemer, Dirk Höper, Angele Breithaupt, Elisa Heuser, Rainer G. Ulrich, Jens H. Kuhn, Kimberly A. Bishop-Lilly, Martin Beer and Tony L. Goldberg

STING cyclic dinucleotide sensing originated in bacteria pp. 429-433

Benjamin R. Morehouse, Apurva A. Govande, Adi Millman, Alexander F. A. Keszei, Brianna Lowey, Gal Ofir, Sichen Shao, Rotem Sorek and Philip J. Kranzusch

A STAT3 palmitoylation cycle promotes TH17 differentiation and colitis pp. 434-439

Mingming Zhang, Lixing Zhou, Yuejie Xu, Min Yang, Yilai Xu, Garrison Paul Komaniecki, Tatsiana Kosciuk, Xiao Chen, Xuan Lu, Xiaoping Zou, Maurine E. Linder and Hening Lin

MeCP2 links heterochromatin condensates and neurodevelopmental disease pp. 440-444

Charles H. Li, Eliot L. Coffey, Alessandra Dall’Agnese, Nancy M. Hannett, Xin Tang, Jonathan E. Henninger, Jesse M. Platt, Ozgur Oksuz, Alicia V. Zamudio, Lena K. Afeyan, Jurian Schuijers, X. Shawn Liu, Styliani Markoulaki, Tenzin Lungjangwa, Gary LeRoy, Devon S. Svoboda, Emile Wogram, Tong Ihn Lee, Rudolf Jaenisch and Richard A. Young

C. elegans interprets bacterial non-coding RNAs to learn pathogenic avoidance pp. 445-451

Rachel Kaletsky, Rebecca S. Moore, Geoffrey D. Vrla, Lance R. Parsons, Zemer Gitai and Coleen T. Murphy

Structural basis for dimerization quality control pp. 452-456

Elijah L. Mena, Predrag Jevtić, Basil J. Greber, Christine L. Gee, Brandon G. Lew, David Akopian, Eva Nogales, John Kuriyan and Michael Rape

Structural basis for pH gating of the two-pore domain K+ channel TASK2 pp. 457-462

Baobin Li, Robert A. Rietmeijer and Stephen G. Brohawn

Marine mammalogy must battle against unpaid work, argues petition pp. 463-464

Madeline Bodin

Fighting fires to save a natural preserve in Brazil pp. 466-466

Patrícia Maia Noronha

2020, volume 586, articles 7828

Author Correction: Coupling dinitrogen and hydrocarbons through aryl migration pp. E10-E10

Sean F. McWilliams, Daniël L. J. Broere, Connor J. V. Halliday, Samuel M. Bhutto, Brandon Q. Mercado and Patrick L. Holland

Author Correction: Lactonization as a general route to β-C(sp3)–H functionalization pp. E11-E11

Zhe Zhuang and Jin-Quan Yu

Author Correction: Floating under a levitating liquid pp. E12-E12

Benjamin Apffel, Filip Novkoski, Antonin Eddi and Emmanuel Fort

Editorial Expression of Concern: Living annulative π-extension polymerization for graphene nanoribbon synthesis pp. E13-E13

Yuuta Yano, Nobuhiko Mitoma, Kaho Matsushima, Feijiu Wang, Keisuke Matsui, Akira Takakura, Yuhei Miyauchi, Hideto Ito and Kenichiro Itami

Plan now to speed vaccine supply for future pandemics pp. 171-171

Kate Bingham

What a Joe Biden presidency would mean for five key science issues pp. 177-180

Amy Maxmen, Nidhi Subbaraman, Jeff Tollefson, Giuliana Viglione and Alexandra Witze

India pushes bold ‘one nation, one subscription’ journal-access plan pp. 181-182

Smriti Mallapaty

Life on Venus? Scientists hunt for the truth pp. 182-183

Jonathan O'Callaghan

What Trump’s Supreme Court pick could mean for science pp. 183-184

Nidhi Subbaraman

Face masks: what the data say pp. 186-189

Lynne Peeples

How Trump damaged science — and why it could take decades to recover pp. 190-194

Jeff Tollefson

Vaughan Jones (1952–2020) pp. 195-195

Davide Castelvecchi

COVID-19 vaccines: how to ensure Africa has access pp. 197-199

John N. Nkengasong, Nicaise Ndembi, Akhona Tshangela and Tajudeen Raji

Funders must mandate and reward open research records pp. 200-200

Ralitsa Madsen

COVID-19 shows UK–EU collaborations are irreplaceable pp. 200-200

Benjamin Fernando, Gordon Brown, Emily Thomas, Michael Head, Paul Nurse and Martin Rees

Japan’s government must seek out expert scientists pp. 200-200

Yoshiyasu Takefuji

Encounters with inequality lead to demands for taxes on the rich pp. 201-202

Colin Tredoux and John Dixon

Inductors enter the world of quantum mechanics pp. 202-203

Seonghoon Woo

Maternal microbes support fetal brain wiring pp. 203-205

Katherine R. Meckel and Drew D. Kiraly

Early onset of planet formation observed in a nascent star system pp. 205-206

Patrick Sheehan

Programmable photonic circuits pp. 207-216

Wim Bogaerts, Daniel Pérez, José Capmany, David A. B. Miller, Joyce Poon, Dirk Englund, Francesco Morichetti and Andrea Melloni

Area-based conservation in the twenty-first century pp. 217-227

Sean L. Maxwell, Victor Cazalis, Nigel Dudley, Michael Hoffmann, Ana S. L. Rodrigues, Sue Stolton, Piero Visconti, Stephen Woodley, Naomi Kingston, Edward Lewis, Martine Maron, Bernardo B. N. Strassburg, Amelia Wenger, Harry D. Jonas, Oscar Venter and James E. M. Watson

Four annular structures in a protostellar disk less than 500,000 years old pp. 228-231

Dominique M. Segura-Cox, Anika Schmiedeke, Jaime E. Pineda, Ian W. Stephens, Manuel Fernández-López, Leslie W. Looney, Paola Caselli, Zhi-Yun Li, Lee G. Mundy, Woojin Kwon and Robert J. Harris

Emergent electromagnetic induction in a helical-spin magnet pp. 232-236

Tomoyuki Yokouchi, Fumitaka Kagawa, Max Hirschberger, Yoshichika Otani, Naoto Nagaosa and Yoshinori Tokura

Near-perfect photon utilization in an air-bridge thermophotovoltaic cell pp. 237-241

Dejiu Fan, Tobias Burger, Sean McSherry, Byungjun Lee, Andrej Lenert and Stephen R. Forrest

Intercepting fleeting cyclic allenes with asymmetric nickel catalysis pp. 242-247

Michael M. Yamano, Andrew V. Kelleghan, Qianzhen Shao, Maude Giroud, Bryan J. Simmons, Bo Li, Shuming Chen, K. N. Houk and Neil K. Garg

A comprehensive quantification of global nitrous oxide sources and sinks pp. 248-256

Hanqin Tian, Rongting Xu, Josep G. Canadell, Rona L. Thompson, Wilfried Winiwarter, Parvadha Suntharalingam, Eric A. Davidson, Philippe Ciais, Robert B. Jackson, Greet Janssens-Maenhout, Michael J. Prather, Pierre Regnier, Naiqing Pan, Shufen Pan, Glen Peters, Hao Shi, Francesco N. Tubiello, Sönke Zaehle, Feng Zhou, Almut Arneth, Gianna Battaglia, Sarah Berthet, Laurent Bopp, Alexander F. Bouwman, Erik T. Buitenhuis, Jinfeng Chang, Martyn P. Chipperfield, Shree R. S. Dangal, Edward Dlugokencky, James W. Elkins, Bradley D. Eyre, Bojie Fu, Bradley Hall, Akihiko Ito, Fortunat Joos, Paul B. Krummel, Angela Landolfi, Goulven G. Laruelle, Ronny Lauerwald, Wei Li, Sebastian Lienert, Taylor Maavara, Michael MacLeod, Dylan B. Millet, Stefan Olin, Prabir K. Patra, Ronald G. Prinn, Peter A. Raymond, Daniel J. Ruiz, Guido R. Werf, Nicolas Vuichard, Junjie Wang, Ray F. Weiss, Kelley C. Wells, Chris Wilson, Jia Yang and Yuanzhi Yao

Local exposure to inequality raises support of people of low wealth for taxing the wealthy pp. 257-261

Melissa L. Sands and Daniel de Kadt

Innovations present in the primate interneuron repertoire pp. 262-269

Fenna M. Krienen, Melissa Goldman, Qiangge Zhang, Ricardo del Rosario, Marta Florio, Robert Machold, Arpiar Saunders, Kirsten Levandowski, Heather Zaniewski, Benjamin Schuman, Carolyn Wu, Alyssa Lutservitz, Christopher D. Mullally, Nora Reed, Elizabeth Bien, Laura Bortolin, Marian Fernandez-Otero, Jessica D. Lin, Alec Wysoker, James Nemesh, David Kulp, Monika Burns, Victor Tkachev, Richard Smith, Christopher A. Walsh, Jordane Dimidschstein, Bernardo Rudy, Leslie Kean, Sabina Berretta, Gord Fishell, Guoping Feng and Steven A. McCarroll

A hypothalamic novelty signal modulates hippocampal memory pp. 270-274

Shuo Chen, Linmeng He, Arthur J. Y. Huang, Roman Boehringer, Vincent Robert, Marie E. Wintzer, Denis Polygalov, Adam Z. Weitemier, Yanqiu Tao, Mingxiao Gu, Steven J. Middleton, Kana Namiki, Hiroshi Hama, Ludivine Therreau, Vivien Chevaleyre, Hiroyuki Hioki, Atsushi Miyawaki, Rebecca A. Piskorowski and Thomas J. McHugh

Phenotypic landscape of intestinal organoid regeneration pp. 275-280

Ilya Lukonin, Denise Serra, Ludivine Challet Meylan, Katrin Volkmann, Janine Baaten, Rui Zhao, Shelly Meeusen, Karyn Colman, Francisca Maurer, Michael B. Stadler, Jeremy Jenkins and Prisca Liberali

The maternal microbiome modulates fetal neurodevelopment in mice pp. 281-286

Helen E. Vuong, Geoffrey N. Pronovost, Drake W. Williams, Elena J. L. Coley, Emily L. Siegler, Austin Qiu, Maria Kazantsev, Chantel J. Wilson, Tomiko Rendon and Elaine Y. Hsiao

Na+ controls hypoxic signalling by the mitochondrial respiratory chain pp. 287-291

Pablo Hernansanz-Agustín, Carmen Choya-Foces, Susana Carregal-Romero, Elena Ramos, Tamara Oliva, Tamara Villa-Piña, Laura Moreno, Alicia Izquierdo-Álvarez, J. Daniel Cabrera-García, Ana Cortés, Ana Victoria Lechuga-Vieco, Pooja Jadiya, Elisa Navarro, Esther Parada, Alejandra Palomino-Antolín, Daniel Tello, Rebeca Acín-Pérez, Juan Carlos Rodríguez-Aguilera, Plácido Navas, Ángel Cogolludo, Iván López-Montero, Álvaro Martínez-del-Pozo, Javier Egea, Manuela G. López, John W. Elrod, Jesús Ruíz-Cabello, Anna Bogdanova, José Antonio Enríquez and Antonio Martínez-Ruiz

Repeat expansions confer WRN dependence in microsatellite-unstable cancers pp. 292-298

Niek van Wietmarschen, Sriram Sridharan, William J. Nathan, Anthony Tubbs, Edmond M. Chan, Elsa Callen, Wei Wu, Frida Belinky, Veenu Tripathi, Nancy Wong, Kyla Foster, Javad Noorbakhsh, Kiran Garimella, Abimael Cruz-Migoni, Joshua A. Sommers, Yongqing Huang, Ashir A. Borah, Jonathan T. Smith, Jeremie Kalfon, Nikolas Kesten, Kasper Fugger, Robert L. Walker, Egor Dolzhenko, Michael A. Eberle, Bruce E. Hayward, Karen Usdin, Catherine H. Freudenreich, Robert M. Brosh, Stephen C. West, Peter J. McHugh, Paul S. Meltzer, Adam J. Bass and André Nussenzweig

Tumoural activation of TLR3–SLIT2 axis in endothelium drives metastasis pp. 299-304

Bernardo Tavora, Tobias Mederer, Kai J. Wessel, Simon Ruffing, Mahan Sadjadi, Marc Missmahl, Benjamin N. Ostendorf, Xuhang Liu, Ji-Young Kim, Olav Olsen, Alana L. Welm, Hani Goodarzi and Sohail F. Tavazoie

CTCF orchestrates long-range cohesin-driven V(D)J recombinational scanning pp. 305-310

Zhaoqing Ba, Jiangman Lou, Adam Yongxin Ye, Hai-Qiang Dai, Edward W. Dring, Sherry G. Lin, Suvi Jain, Nia Kyritsis, Kyong-Rim Kieffer-Kwon, Rafael Casellas and Frederick W. Alt

Structural basis of salicylic acid perception by Arabidopsis NPR proteins pp. 311-316

Wei Wang, John Withers, Heng Li, Paul J. Zwack, Domnița-Valeria Rusnac, Hui Shi, Lijing Liu, Shunping Yan, Thomas R. Hinds, Mikelos Guttman, Xinnian Dong and Ning Zheng

Structures of fungal and plant acetohydroxyacid synthases pp. 317-321

Thierry Lonhienne, Yu Shang Low, Mario D. Garcia, Tristan Croll, Yan Gao, Quan Wang, Lou Brillault, Craig M. Williams, James A. Fraser, Ross P. McGeary, Nicholas P. West, Michael J. Landsberg, Zihe Rao, Gerhard Schenk and Luke W. Guddat

The visa woes that shattered scientists’ American dreams pp. 323-325

Virginia Gewin

Flying through an undersea ‘stained-glass window’ pp. 328-328

Kendall Powell

2020, volume 586, articles 7827

Reevaluating bipedalism in Danuvius pp. E1-E3

Scott A. Williams, Thomas C. Prang, Marc R. Meyer, Gabrielle A. Russo and Liza J. Shapiro

Reply to: Reevaluating bipedalism in Danuvius pp. E4-E5

Madelaine Böhme, Nikolai Spassov, Jeremy M. DeSilva and David R. Begun

Author Correction: Self-assembled poly-catenanes from supramolecular toroidal building blocks pp. E6-E6

Sougata Datta, Yasuki Kato, Seiya Higashiharaguchi, Keisuke Aratsu, Atsushi Isobe, Takuho Saito, Deepak D. Prabhu, Yuichi Kitamoto, Martin J. Hollamby, Andrew J. Smith, Robert Dalgliesh, Najet Mahmoudi, Luca Pesce, Claudio Perego, Giovanni M. Pavan and Shiki Yagai

Author Correction: Molecular architecture of lineage allocation and tissue organization in early mouse embryo pp. E7-E7

Guangdun Peng, Shengbao Suo, Guizhong Cui, Fang Yu, Ran Wang, Jun Chen, Shirui Chen, Zhiwen Liu, Guoyu Chen, Yun Qian, Patrick P. L. Tam, Jing-Dong J. Han and Naihe Jing

Author Correction: Impact of ionizing radiation on superconducting qubit coherence pp. E8-E8

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Publisher Correction: Mechanics of a multilayer epithelium instruct tumour architecture and function pp. E9-E9

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The US National Academy of Sciences can now kick out harassers. So why hasn’t it? pp. 15-16

Giuliana Viglione

COVID-vaccine results are on the way — and scientists’ concerns are growing pp. 16-17

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The first-ever image of a black hole is now a movie pp. 18-19

Davide Castelvecchi

Censored: Australian scientists say suppression of environment research is getting worse pp. 19-20

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‘Apocalyptic’ fires are ravaging the world’s largest tropical wetland pp. 20-21

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Alexa, do I have COVID-19? pp. 22-25

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Democracy suffers when government statistics fail pp. 27-28

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The worst is yet to come for the Greenland ice sheet pp. 29-30

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Fractional antiferromagnetic skyrmion lattice induced by anisotropic couplings pp. 37-41

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Graphene-based Josephson junction microwave bolometer pp. 42-46

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Bolometer operating at the threshold for circuit quantum electrodynamics pp. 47-51

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Active particles induce large shape deformations in giant lipid vesicles pp. 52-56

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Concentric liquid reactors for chemical synthesis and separation pp. 57-63

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The ecological and genomic basis of explosive adaptive radiation pp. 75-79

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Genome-wide detection of tandem DNA repeats that are expanded in autism pp. 80-86

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Deep posteromedial cortical rhythm in dissociation pp. 87-94

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Shared yet dissociable neural codes across eye gaze, valence and expectation pp. 95-100

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Human germinal centres engage memory and naive B cells after influenza vaccination pp. 127-132

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Patrícia Maia Noronha