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2019, volume 568, articles 7753

Why are Canada’s scientists getting political? pp. S1-S3

Brian Owens

Author Correction: Rubber bands reduce the cost of carrying loads pp. E12-E12

Lawrence C. Rome, Louis Flynn and Taeseung D. Yoo

Author Correction: Spatially resolved steady-state negative capacitance pp. E13-E13

Ajay K. Yadav, Kayla X. Nguyen, Zijian Hong, Pablo García-Fernández, Pablo Aguado-Puente, Christopher T. Nelson, Sujit Das, Bhagwati Prasad, Daewoong Kwon, Suraj Cheema, Asif I. Khan, Chenming Hu, Jorge Íñiguez, Javier Junquera, Long-Qing Chen, David A. Muller, Ramamoorthy Ramesh and Sayeef Salahuddin

Publisher Correction: Attachment of the blastoderm to the vitelline envelope affects gastrulation of insects pp. E14-E14

Stefan Münster, Akanksha Jain, Alexander Mietke, Anastasios Pavlopoulos, Stephan W. Grill and Pavel Tomancak

Rein in the four horsemen of irreproducibility pp. 435-435

Dorothy Bishop

CRISPR gene-editing creates wave of exotic model organisms pp. 441-442

Sara Reardon

How long do neutrons live? Physicists close in on decades-old puzzle pp. 442-443

Alexandra Witze

How US–China political tensions are affecting science pp. 443-444

Andrew Silver, Jeff Tollefson and Elizabeth Gibney

Genetic study homes in on height’s heritability mystery pp. 444-445

Linda Geddes

The largest study involving transgender people is providing long-sought insights about their health pp. 446-449

Sara Reardon

Protect our right to light pp. 451-453

Karolina M. Zielinska-Dabkowska and Kyra Xavia

Plague in San Francisco: rats, racism and reform pp. 454-455

Tilli Tansey

Blood money: the biotech debacle of Theranos on screen pp. 455-456

Heidi Ledford

Artist of deep time pp. 457-457

Philip Ball

Manage risk of accidental gene editing of germline pp. 458-458

Darren G. Monckton

When a conflict of interest is not a conflict pp. 458-458

René Bernards

Germline-editing moratorium — why we should resist it pp. 458-458

Harald König

A European initiative to unclog pipeline for new medicines pp. 458-458

Malcolm Macleod and Thomas Steckler

Krill harvesting: rush on red gold endangers ecosystems pp. 458-458

Jørgen Schou Christiansen

Sydney Brenner (1927-2019) pp. 459-459

Errol Friedberg

Dark-matter detector observes exotic nuclear decay pp. 462-463

Jouni Suhonen

Lethal clues to cancer-cell vulnerability pp. 463-464

Felix Y. Feng and Luke A. Gilbert

A fresh approach to synthesizing ammonia from air and water pp. 464-466

Máté J. Bezdek and Paul J. Chirik

Brain implants that let you speak your mind pp. 466-467

Chethan Pandarinath and Yahia H. Ali

Dynamic polymer network points the way to truly recyclable plastics pp. 467-468

Coralie Jehanno and Haritz Sardon

The new frontier of gravitational waves pp. 469-476

M. Coleman Miller and Nicolás Yunes

Machine behaviour pp. 477-486

Iyad Rahwan, Manuel Cebrian, Nick Obradovich, Josh Bongard, Jean-François Bonnefon, Cynthia Breazeal, Jacob W. Crandall, Nicholas A. Christakis, Iain D. Couzin, Matthew Jackson, Nicholas R. Jennings, Ece Kamar, Isabel M. Kloumann, Hugo Larochelle, David Lazer, Richard McElreath, Alan Mislove, David C. Parkes, Alex ‘Sandy’ Pentland, Margaret E. Roberts, Azim Shariff, Joshua B. Tenenbaum and Michael Wellman

Forearc carbon sink reduces long-term volatile recycling into the mantle pp. 487-492

P. H. Barry, J. M. Moor, D. Giovannelli, M. Schrenk, D. R. Hummer, T. Lopez, C. A. Pratt, Y. Alpízar Segura, A. Battaglia, P. Beaudry, G. Bini, M. Cascante, G. d’Errico, M. di Carlo, D. Fattorini, K. Fullerton, E. Gazel, G. González, S. A. Halldórsson, K. Iacovino, T. Ilanko, J. T. Kulongoski, E. Manini, M. Martínez, H. Miller, M. Nakagawa, S. Ono, S. Patwardhan, C. J. Ramírez, F. Regoli, F. Smedile, S. Turner, C. Vetriani, M. Yücel, C. J. Ballentine, T. P. Fischer, D. R. Hilton and K. G. Lloyd

Speech synthesis from neural decoding of spoken sentences pp. 493-498

Gopala K. Anumanchipalli, Josh Chartier and Edward F. Chang

A new genomic blueprint of the human gut microbiota pp. 499-504

Alexandre Almeida, Alex L. Mitchell, Miguel Boland, Samuel C. Forster, Gregory B. Gloor, Aleksandra Tarkowska, Trevor D. Lawley and Robert D. Finn

New insights from uncultivated genomes of the global human gut microbiome pp. 505-510

Stephen Nayfach, Zhou Jason Shi, Rekha Seshadri, Katherine S. Pollard and Nikos C. Kyrpides

Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens pp. 511-516

Fiona M. Behan, Francesco Iorio, Gabriele Picco, Emanuel Gonçalves, Charlotte M. Beaver, Giorgia Migliardi, Rita Santos, Yanhua Rao, Francesco Sassi, Marika Pinnelli, Rizwan Ansari, Sarah Harper, David Adam Jackson, Rebecca McRae, Rachel Pooley, Piers Wilkinson, Dieudonne Meer, David Dow, Carolyn Buser-Doepner, Andrea Bertotti, Livio Trusolino, Euan A. Stronach, Julio Saez-Rodriguez, Kosuke Yusa and Mathew J. Garnett

No detection of methane on Mars from early ExoMars Trace Gas Orbiter observations pp. 517-520

Oleg Korablev, Ann Carine Vandaele, Franck Montmessin, Anna A. Fedorova, Alexander Trokhimovskiy, François Forget, Franck Lefèvre, Frank Daerden, Ian R. Thomas, Loïc Trompet, Justin T. Erwin, Shohei Aoki, Séverine Robert, Lori Neary, Sébastien Viscardy, Alexey V. Grigoriev, Nikolay I. Ignatiev, Alexey Shakun, Andrey Patrakeev, Denis A. Belyaev, Jean-Loup Bertaux, Kevin S. Olsen, Lucio Baggio, Juan Alday, Yuriy S. Ivanov, Bojan Ristic, Jon Mason, Yannick Willame, Cédric Depiesse, Laszlo Hetey, Sophie Berkenbosch, Roland Clairquin, Claudio Queirolo, Bram Beeckman, Eddy Neefs, Manish R. Patel, Giancarlo Bellucci, Jose-Juan López-Moreno, Colin F. Wilson, Giuseppe Etiope, Lev Zelenyi, Håkan Svedhem and Jorge L. Vago

Martian dust storm impact on atmospheric H2O and D/H observed by ExoMars Trace Gas Orbiter pp. 521-525

Ann Carine Vandaele, Oleg Korablev, Frank Daerden, Shohei Aoki, Ian R. Thomas, Francesca Altieri, Miguel López-Valverde, Geronimo Villanueva, Giuliano Liuzzi, Michael D. Smith, Justin T. Erwin, Loïc Trompet, Anna A. Fedorova, Franck Montmessin, Alexander Trokhimovskiy, Denis A. Belyaev, Nikolay I. Ignatiev, Mikhail Luginin, Kevin S. Olsen, Lucio Baggio, Juan Alday, Jean-Loup Bertaux, Daria Betsis, David Bolsée, R. Todd Clancy, Edward Cloutis, Cédric Depiesse, Bernd Funke, Maia Garcia-Comas, Jean-Claude Gérard, Marco Giuranna, Francisco Gonzalez-Galindo, Alexey V. Grigoriev, Yuriy S. Ivanov, Jacek Kaminski, Ozgur Karatekin, Franck Lefèvre, Stephen Lewis, Manuel López-Puertas, Arnaud Mahieux, Igor Maslov, Jon Mason, Michael J. Mumma, Lori Neary, Eddy Neefs, Andrey Patrakeev, Dmitry Patsaev, Bojan Ristic, Séverine Robert, Frédéric Schmidt, Alexey Shakun, Nicholas A. Teanby, Sébastien Viscardy, Yannick Willame, James Whiteway, Valérie Wilquet, Michael J. Wolff, Giancarlo Bellucci, Manish R. Patel, Jose-Juan López-Moreno, François Forget, Colin F. Wilson, Håkan Svedhem, Jorge L. Vago and Daniel Rodionov

Predicting disruptive instabilities in controlled fusion plasmas through deep learning pp. 526-531

Julian Kates-Harbeck, Alexey Svyatkovskiy and William Tang

Molybdenum-catalysed ammonia production with samarium diiodide and alcohols or water pp. 536-540

Yuya Ashida, Kazuya Arashiba, Kazunari Nakajima and Yoshiaki Nishibayashi

Developmental origin, functional maintenance and genetic rescue of osteoclasts pp. 541-545

Christian E. Jacome-Galarza, Gulce I. Percin, James T. Muller, Elvira Mass, Tomi Lazarov, Jiri Eitler, Martina Rauner, Vijay K. Yadav, Lucile Crozet, Mathieu Bohm, Pierre-Louis Loyher, Gerard Karsenty, Claudia Waskow and Frederic Geissmann

Nuclear positioning facilitates amoeboid migration along the path of least resistance pp. 546-550

Jörg Renkawitz, Aglaja Kopf, Julian Stopp, Ingrid Vries, Meghan K. Driscoll, Jack Merrin, Robert Hauschild, Erik S. Welf, Gaudenz Danuser, Reto Fiolka and Michael Sixt

WRN helicase is a synthetic lethal target in microsatellite unstable cancers pp. 551-556

Edmond M. Chan, Tsukasa Shibue, James M. McFarland, Benjamin Gaeta, Mahmoud Ghandi, Nancy Dumont, Alfredo Gonzalez, Justine S. McPartlan, Tianxia Li, Yanxi Zhang, Jie Liu, Jean-Bernard Lazaro, Peili Gu, Cortt G. Piett, Annie Apffel, Syed O. Ali, Rebecca Deasy, Paula Keskula, Raymond W. S. Ng, Emma A. Roberts, Elizaveta Reznichenko, Lisa Leung, Maria Alimova, Monica Schenone, Mirazul Islam, Yosef E. Maruvka, Yang Liu, Jatin Roper, Srivatsan Raghavan, Marios Giannakis, Yuen-Yi Tseng, Zachary D. Nagel, Alan D’Andrea, David E. Root, Jesse S. Boehm, Gad Getz, Sandy Chang, Todd R. Golub, Aviad Tsherniak, Francisca Vazquez and Adam J. Bass

p38γ is essential for cell cycle progression and liver tumorigenesis pp. 557-560

Antonia Tomás-Loba, Elisa Manieri, Bárbara González-Terán, Alfonso Mora, Luis Leiva-Vega, Ayelén M. Santamans, Rafael Romero-Becerra, Elena Rodríguez, Aránzazu Pintor-Chocano, Ferran Feixas, Juan Antonio López, Beatriz Caballero, Marianna Trakala, Óscar Blanco, Jorge L. Torres, Lourdes Hernández-Cosido, Valle Montalvo-Romeral, Nuria Matesanz, Marta Roche-Molina, Juan Antonio Bernal, Hannah Mischo, Marta León, Ainoa Caballero, Diego Miranda-Saavedra, Jesús Ruiz-Cabello, Yulia A. Nevzorova, Francisco Javier Cubero, Jerónimo Bravo, Jesús Vázquez, Marcos Malumbres, Miguel Marcos, Sílvia Osuna and Guadalupe Sabio

Precise therapeutic gene correction by a simple nuclease-induced double-stranded break pp. 561-565

Sukanya Iyer, Sneha Suresh, Dongsheng Guo, Katelyn Daman, Jennifer C. J. Chen, Pengpeng Liu, Marina Zieger, Kevin Luk, Benjamin P. Roscoe, Christian Mueller, Oliver D. King, Charles P. Emerson and Scot A. Wolfe

An allosteric mechanism for potent inhibition of human ATP-citrate lyase pp. 566-570

Jia Wei, Silvana Leit, Jun Kuai, Eric Therrien, Salma Rafi, H. James Harwood, Byron DeLaBarre and Liang Tong

Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle pp. 571-575

Koen H. G. Verschueren, Clement Blanchet, Jan Felix, Ann Dansercoer, Dirk De Vos, Yehudi Bloch, Jozef Van Beeumen, Dmitri Svergun, Irina Gutsche, Savvas N. Savvides and Kenneth Verstraete

Retraction Note: KAT5 tyrosine phosphorylation couples chromatin sensing to ATM signalling pp. 576-576

Abderrahmane Kaidi and Stephen P. Jackson

Automation: Chemistry shoots for the Moon pp. 577-579

Katharine Sanderson

A simple approach to dating bones pp. 579-579

Jeffrey M. Perkel

Junior AI researchers are in demand by universities and industry pp. 581-583

Roberta Kwok

Gulliver at home pp. 586-586

Anatoly Belilovsky

2019, volume 568, articles 7752

Author Correction: Targeted therapy in patients with PIK3CA-related overgrowth syndrome pp. E6-E6

Quitterie Venot, Thomas Blanc, Smail Hadj Rabia, Laureline Berteloot, Sophia Ladraa, Jean-Paul Duong, Estelle Blanc, Simon C. Johnson, Clément Hoguin, Olivia Boccara, Sabine Sarnacki, Nathalie Boddaert, Stephanie Pannier, Frank Martinez, Sato Magassa, Junna Yamaguchi, Bertrand Knebelmann, Pierre Merville, Nicolas Grenier, Dominique Joly, Valérie Cormier-Daire, Caroline Michot, Christine Bole-Feysot, Arnaud Picard, Véronique Soupre, Stanislas Lyonnet, Jeremy Sadoine, Lotfi Slimani, Catherine Chaussain, Cécile Laroche-Raynaud, Laurent Guibaud, Christine Broissand, Jeanne Amiel, Christophe Legendre, Fabiola Terzi and Guillaume Canaud

Author Correction: Consistent success in life-supporting porcine cardiac xenotransplantation pp. E7-E7

Matthias Längin, Tanja Mayr, Bruno Reichart, Sebastian Michel, Stefan Buchholz, Sonja Guethoff, Alexey Dashkevich, Andrea Baehr, Stefanie Egerer, Andreas Bauer, Maks Mihalj, Alessandro Panelli, Lara Issl, Jiawei Ying, Ann Kathrin Fresch, Ines Buttgereit, Maren Mokelke, Julia Radan, Fabian Werner, Isabelle Lutzmann, Stig Steen, Trygve Sjöberg, Audrius Paskevicius, Liao Qiuming, Riccardo Sfriso, Robert Rieben, Maik Dahlhoff, Barbara Kessler, Elisabeth Kemter, Mayuko Kurome, Valeri Zakhartchenko, Katharina Klett, Rabea Hinkel, Christian Kupatt, Almuth Falkenau, Simone Reu, Reinhard Ellgass, Rudolf Herzog, Uli Binder, Günter Wich, Arne Skerra, David Ayares, Alexander Kind, Uwe Schönmann, Franz-Josef Kaup, Christian Hagl, Eckhard Wolf, Nikolai Klymiuk, Paolo Brenner and Jan-Michael Abicht

Author Correction: CasX enzymes comprise a distinct family of RNA-guided genome editors pp. E8-E10

Jun-Jie Liu, Natalia Orlova, Benjamin L. Oakes, Enbo Ma, Hannah B. Spinner, Katherine L. M. Baney, Jonathan Chuck, Dan Tan, Gavin J. Knott, Lucas B. Harrington, Basem Al-Shayeb, Alexander Wagner, Julian Brötzmann, Brett T. Staahl, Kian L. Taylor, John Desmarais, Eva Nogales and Jennifer A. Doudna

Publisher Correction: DNA sequencing at 40: past, present and future pp. E11-E11

Jay Shendure, Shankar Balasubramanian, George M. Church, Walter Gilbert, Jane Rogers, Jeffery A. Schloss and Robert H. Waterston

Safeguards for human studies can’t cope with big data pp. 277-277

Nathaniel Raymond

Pig brains kept alive outside body for hours after death pp. 283-284

Sara Reardon

Black hole pictured for first time — in spectacular detail pp. 284-285

Davide Castelvecchi

Indonesian mega-science agency in the balance as election begins pp. 286-287

Dyna Rochmyaningsih

Israeli spacecraft Beresheet crashes into the Moon pp. 286-286

Elizabeth Gibney

Mexican ecologists push to transform prison island into nature reserve pp. 287-288

Emiliano Rodríguez Mega

Facing up to injustice in genome science pp. 290-293

Giorgia Guglielmi

Indigenous groups look to ancient DNA to bring their ancestors home pp. 294-297

Nicky Phillips

Part-revived pig brains raise slew of ethical quandaries pp. 299-302

Nita A. Farahany, Henry T. Greely and Charles M. Giattino

Pig experiment challenges assumptions around brain damage in people pp. 302-304

Stuart Youngner and Insoo Hyun

Einstein, Eddington and the 1919 eclipse pp. 306-307

Peter Coles

Newton’s opus revisited, bodily surprises and the secret lives of dogs: New in paperback pp. 308-314

Mary Craig

The forgotten scientists who paved the way to the double helix pp. 308-309

Jan Witkowski

A struggle for the soul of theoretical physics pp. 309-311

Jon Butterworth

Moon mapper, Sun spotter: the astonishing Thomas Harriot pp. 311-312

Georgina Ferry

Seven nations that survived apocalypse pp. 312-314

Richard Rhodes

The sorrows of psychiatry pp. 314-315

Alison Abbott

Brexit: EU conservation suffers too pp. 316-316

Stefano Canessa, Alejandra Morán Ordóñez and Virgilio Hermoso

Gene-edited livestock: consumers may say no pp. 316-316

Maria José Hötzel and Marina A. G. von Keyserlingk

Coal research institute kept the power on in Ukraine pp. 316-316

Nataliya Dunayevska

An adventure in predatory publishing: the contents of two medicine cabinets pp. 316-316

Dan H. Shugar and Ian Kane

EU presidency: Romanian research minister questions evolution pp. 316-316

Ștefan Szedlacsek, Mihai Miclăuș and Cristian Presură

Elimination of unfit cells in young and ageing skin pp. 318-319

Ganna Bilousova and James DeGregori

A closer look at lightning reveals needle-like structures pp. 319-320

Earle Williams and Joan Montanyà

Conformation of the native HIV-1 envelope protein raises questions for vaccine design pp. 321-322

Alexandra Trkola

Electrifying skyrmion bubbles pp. 322-323

Pavlo Zubko

A mouse model for the most common form of heart failure pp. 324-325

Dulguun Amgalan and Richard N. Kitsis

Machine-learning techniques used to accurately predict battery life pp. 325-326

Maitane Berecibar

Multi-faceted particle pumps drive carbon sequestration in the ocean pp. 327-335

Philip W. Boyd, Hervé Claustre, Marina Levy, David A. Siegel and Thomas Weber

Restoration of brain circulation and cellular functions hours post-mortem pp. 336-343

Zvonimir Vrselja, Stefano G. Daniele, John Silbereis, Francesca Talpo, Yury M. Morozov, André M. M. Sousa, Brian S. Tanaka, Mario Skarica, Mihovil Pletikos, Navjot Kaur, Zhen W. Zhuang, Zhao Liu, Rafeed Alkawadri, Albert J. Sinusas, Stephen R. Latham, Stephen G. Waxman and Nenad Sestan

Stem cell competition orchestrates skin homeostasis and ageing pp. 344-350

Nan Liu, Hiroyuki Matsumura, Tomoki Kato, Shizuko Ichinose, Aki Takada, Takeshi Namiki, Kyosuke Asakawa, Hironobu Morinaga, Yasuaki Mohri, Adèle Arcangelis, Elisabeth Geroges-Labouesse, Daisuke Nanba and Emi K. Nishimura

Nitrosative stress drives heart failure with preserved ejection fraction pp. 351-356

Gabriele G. Schiattarella, Francisco Altamirano, Dan Tong, Kristin M. French, Elisa Villalobos, Soo Young Kim, Xiang Luo, Nan Jiang, Herman I. May, Zhao V. Wang, Theodore M. Hill, Pradeep P. A. Mammen, Jian Huang, Dong I. Lee, Virginia S. Hahn, Kavita Sharma, David A. Kass, Sergio Lavandero, Thomas G. Gillette and Joseph A. Hill

Astrophysical detection of the helium hydride ion HeH+ pp. 357-359

Rolf Güsten, Helmut Wiesemeyer, David Neufeld, Karl M. Menten, Urs U. Graf, Karl Jacobs, Bernd Klein, Oliver Ricken, Christophe Risacher and Jürgen Stutzki

Needle-like structures discovered on positively charged lightning branches pp. 360-363

B. M. Hare, O. Scholten, J. Dwyer, T. N. G. Trinh, S. Buitink, S. Veen, A. Bonardi, A. Corstanje, H. Falcke, J. R. Hörandel, T. Huege, P. Mitra, K. Mulrey, A. Nelles, J. P. Rachen, L. Rossetto, P. Schellart, T. Winchen, J. Anderson, I. M. Avruch, M. J. Bentum, R. Blaauw, J. W. Broderick, W. N. Brouw, M. Brüggen, H. R. Butcher, B. Ciardi, R. A. Fallows, E. Geus, S. Duscha, J. Eislöffel, M. A. Garrett, J. M. Grießmeier, A. W. Gunst, M. P. Haarlem, J. W. T. Hessels, M. Hoeft, A. J. Horst, M. Iacobelli, L. V. E. Koopmans, A. Krankowski, P. Maat, M. J. Norden, H. Paas, M. Pandey-Pommier, V. N. Pandey, R. Pekal, R. Pizzo, W. Reich, H. Rothkaehl, H. J. A. Röttgering, A. Rowlinson, D. J. Schwarz, A. Shulevski, J. Sluman, O. Smirnov, M. Soida, M. Tagger, M. C. Toribio, A. Ardenne, R. A. M. J. Wijers, R. J. van Weeren, O. Wucknitz, P. Zarka and P. Zucca

Measurement of quantum back action in the audio band at room temperature pp. 364-367

Jonathan Cripe, Nancy Aggarwal, Robert Lanza, Adam Libson, Robinjeet Singh, Paula Heu, David Follman, Garrett D. Cole, Nergis Mavalvala and Thomas Corbitt

Observation of room-temperature polar skyrmions pp. 368-372

S. Das, Y. L. Tang, Z. Hong, M. A. P. Gonçalves, M. R. McCarter, C. Klewe, K. X. Nguyen, F. Gómez-Ortiz, P. Shafer, E. Arenholz, V. A. Stoica, S.-L. Hsu, B. Wang, C. Ophus, J. F. Liu, C. T. Nelson, S. Saremi, B. Prasad, A. B. Mei, D. G. Schlom, J. Íñiguez, P. García-Fernández, D. A. Muller, L. Q. Chen, J. Junquera, L. W. Martin and R. Ramesh

Broadband electro-optic frequency comb generation in a lithium niobate microring resonator pp. 373-377

Mian Zhang, Brandon Buscaino, Cheng Wang, Amirhassan Shams-Ansari, Christian Reimer, Rongrong Zhu, Joseph M. Kahn and Marko Lončar

Resonant electro-optic frequency comb pp. 378-381

Alfredo Rueda, Florian Sedlmeir, Madhuri Kumari, Gerd Leuchs and Harald G. L. Schwefel

Global glacier mass changes and their contributions to sea-level rise from 1961 to 2016 pp. 382-386

M. Zemp, M. Huss, E. Thibert, N. Eckert, R. McNabb, J. Huber, M. Barandun, H. Machguth, S. U. Nussbaumer, I. Gärtner-Roer, L. Thomson, F. Paul, F. Maussion, S. Kutuzov and J. G. Cogley

Global warming impairs stock–recruitment dynamics of corals pp. 387-390

Terry P. Hughes, James T. Kerry, Andrew H. Baird, Sean R. Connolly, Tory J. Chase, Andreas Dietzel, Tessa Hill, Andrew S. Hoey, Mia O. Hoogenboom, Mizue Jacobson, Ailsa Kerswell, Joshua S. Madin, Abbie Mieog, Allison S. Paley, Morgan S. Pratchett, Gergely Torda and Rachael M. Woods

Mapping changes in housing in sub-Saharan Africa from 2000 to 2015 pp. 391-394

Lucy S. Tusting, Donal Bisanzio, Graham Alabaster, Ewan Cameron, Richard Cibulskis, Michael Davies, Seth Flaxman, Harry S. Gibson, Jakob Knudsen, Charles Mbogo, Fredros O. Okumu, Lorenz Seidlein, Daniel J. Weiss, Steve W. Lindsay, Peter W. Gething and Samir Bhatt

Attachment of the blastoderm to the vitelline envelope affects gastrulation of insects pp. 395-399

Stefan Münster, Akanksha Jain, Alexander Mietke, Anastasios Pavlopoulos, Stephan W. Grill and Pavel Tomancak

Object-vector coding in the medial entorhinal cortex pp. 400-404

Øyvind Arne Høydal, Emilie Ranheim Skytøen, Sebastian Ola Andersson, May-Britt Moser and Edvard I. Moser

Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2 pp. 405-409

Lei Zhou, Coco Chu, Fei Teng, Nicholas J. Bessman, Jeremy Goc, Endi K. Santosa, Gregory G. Putzel, Hiroki Kabata, Judith R. Kelsen, Robert N. Baldassano, Manish A. Shah, Robbyn E. Sockolow, Eric Vivier, Gérard Eberl, Kendall A. Smith and Gregory F. Sonnenberg

Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer pp. 410-414

Wantong Yao, Johnathon L. Rose, Wei Wang, Sahil Seth, Hong Jiang, Ayumu Taguchi, Jintan Liu, Liang Yan, Avnish Kapoor, Pingping Hou, Ziheng Chen, Qiuyun Wang, Luigi Nezi, Zhaohui Xu, Jun Yao, Baoli Hu, Piergiorgio F. Pettazzoni, I Lin Ho, Ningping Feng, Vandhana Ramamoorthy, Shan Jiang, Pingna Deng, Grace J. Ma, Peter Den, Zhi Tan, Shu Xing Zhang, Huamin Wang, Y. Alan Wang, Angela K. Deem, Jason B. Fleming, Alessandro Carugo, Timothy P. Heffernan, Anirban Maitra, Andrea Viale, Haoqiang Ying, Samir Hanash, Ronald A. DePinho and Giulio F. Draetta

Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET pp. 415-419

Maolin Lu, Xiaochu Ma, Luis R. Castillo-Menendez, Jason Gorman, Nirmin Alsahafi, Utz Ermel, Daniel S. Terry, Michael Chambers, Dongjun Peng, Baoshan Zhang, Tongqing Zhou, Nick Reichard, Kevin Wang, Jonathan R. Grover, Brennan P. Carman, Matthew R. Gardner, Ivana Nikić-Spiegel, Akihiro Sugawara, James Arthos, Edward A. Lemke, Amos B. Smith, Michael Farzan, Cameron Abrams, James B. Munro, Adrian B. McDermott, Andrés Finzi, Peter D. Kwong, Scott C. Blanchard, Joseph G. Sodroski and Walther Mothes

Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules pp. 420-423

Benjamin Falcon, Jasenko Zivanov, Wenjuan Zhang, Alexey G. Murzin, Holly J. Garringer, Ruben Vidal, R. Anthony Crowther, Kathy L. Newell, Bernardino Ghetti, Michel Goedert and Sjors H. W. Scheres

Why you need a support team pp. 425-426

Ruth Gotian

The fast stuff pp. 428-428

George Zebrowski

2019, volume 568, articles 7751

Author Correction: Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells pp. E3-E3

Dali Han, Jun Liu, Chuanyuan Chen, Lihui Dong, Yi Liu, Renbao Chang, Xiaona Huang, Yuanyuan Liu, Jianying Wang, Urszula Dougherty, Marc B. Bissonnette, Bin Shen, Ralph R. Weichselbaum, Meng Michelle Xu and Chuan He

Author Correction: Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution pp. E4-E4

Takahiro Masuda, Roman Sankowski, Ori Staszewski, Chotima Böttcher, Lukas Amann, Sagar, Christian Scheiwe, Stefan Nessler, Patrik Kunz, Geert Loo, Volker Arnd Coenen, Peter Christoph Reinacher, Anna Michel, Ulrich Sure, Ralf Gold, Dominic Grün, Josef Priller, Christine Stadelmann and Marco Prinz

Author Correction: Universal resilience patterns in complex networks pp. E5-E5

Jianxi Gao, Baruch Barzel and Albert-László Barabási

Train students to navigate ethical swamps pp. 145-145

Mary A. Allen

Racism rife at top South African university, says report pp. 151-152

Linda Nordling

Australian budget fails to impress scientists pp. 152-153

Smriti Mallapaty

Mars methane hunt comes up empty, flummoxing scientists pp. 153-154

Alexandra Witze

Cancer geneticists tackle troubling ethnic bias in studies pp. 154-155

Heidi Ledford

Brazil’s government freezes nearly half of its science spending pp. 155-156

Claudio Angelo

Ocean uproar: saving marine life from a barrage of noise pp. 158-161

Nicola Jones

Rethink government with AI pp. 163-165

Helen Margetts and Cosmina Dorobantu

A realist takes on quantum mechanics pp. 166-167

Graham Farmelo

Worldwide wayfaring, the human cost of the big thaw, and marine die-offs: Books in brief pp. 167-167

Barbara Kiser

Alexander von Humboldt: the graphic novel pp. 168-169

Alison Abbott

The return of cancer’s magic bullet pp. 169-170

Gerard Evan

Dams: weigh pros and cons case by case pp. 171-171

John A. Harrison

Don’t let damage to wetlands cancel out the benefits of hydropower pp. 171-171

Virgilio Hermoso, Miguel Clavero and Andy J. Green

Sex is a biological variable — in the brain too pp. 171-171

Rhonda Voskuhl and Sabra Klein

Munk’s sonic blunder pp. 171-171

Thomas J. Murphy

Robots on the run pp. 174-175

Hod Lipson

Second example reported of a stem-cell transplant in the clinic leading to HIV remission pp. 175-176

Timothy J. Henrich

Previously unknown human species found in Asia raises questions about early hominin dispersals from Africa pp. 176-178

Matthew W. Tocheri

Correlations detected in a quantum vacuum pp. 178-179

Andrey S. Moskalenko and Timothy C Ralph

Genetic paradox explained by nonsense pp. 179-180

Miles F. Wilkinson

A new species of Homo from the Late Pleistocene of the Philippines pp. 181-186

Florent Détroit, Armand Salvador Mijares, Julien Corny, Guillaume Daver, Clément Zanolli, Eusebio Dizon, Emil Robles, Rainer Grün and Philip J. Piper

CD22 blockade restores homeostatic microglial phagocytosis in ageing brains pp. 187-192

John V. Pluvinage, Michael S. Haney, Benjamin A. H. Smith, Jerry Sun, Tal Iram, Liana Bonanno, Lulin Li, Davis P. Lee, David W. Morgens, Andrew C. Yang, Steven R. Shuken, David Gate, Madeleine Scott, Purvesh Khatri, Jian Luo, Carolyn R. Bertozzi, Michael C. Bassik and Tony Wyss-Coray

Genetic compensation triggered by mutant mRNA degradation pp. 193-197

Mohamed A. El-Brolosy, Zacharias Kontarakis, Andrea Rossi, Carsten Kuenne, Stefan Günther, Nana Fukuda, Khrievono Kikhi, Giulia L. M. Boezio, Carter M. Takacs, Shih-Lei Lai, Ryuichi Fukuda, Claudia Gerri, Antonio J. Giraldez and Didier Y. R. Stainier

A magnetar-powered X-ray transient as the aftermath of a binary neutron-star merger pp. 198-201

Y. Q. Xue, X. C. Zheng, Y. Li, W. N. Brandt, B. Zhang, B. Luo, B.-B. Zhang, F. E. Bauer, H. Sun, B. D. Lehmer, X.-F. Wu, G. Yang, X. Kong, J. Y. Li, M. Y. Sun, J.-X. Wang and F. Vito

Electric field correlation measurements on the electromagnetic vacuum state pp. 202-206

Ileana-Cristina Benea-Chelmus, Francesca Fabiana Settembrini, Giacomo Scalari and Jérôme Faist

Quantum Kibble–Zurek mechanism and critical dynamics on a programmable Rydberg simulator pp. 207-211

Alexander Keesling, Ahmed Omran, Harry Levine, Hannes Bernien, Hannes Pichler, Soonwon Choi, Rhine Samajdar, Sylvain Schwartz, Pietro Silvi, Subir Sachdev, Peter Zoller, Manuel Endres, Markus Greiner, Vladan Vuletić and Mikhail D. Lukin

Ultrafast spin-lasers pp. 212-215

Markus Lindemann, Gaofeng Xu, Tobias Pusch, Rainer Michalzik, Martin R. Hofmann, Igor Žutić and Nils C. Gerhardt

Production of phosphorene nanoribbons pp. 216-220

Mitchell C. Watts, Loren Picco, Freddie S. Russell-Pavier, Patrick L. Cullen, Thomas S. Miller, Szymon P. Bartuś, Oliver D. Payton, Neal T. Skipper, Vasiliki Tileli and Christopher A. Howard

Five decades of northern land carbon uptake revealed by the interhemispheric CO2 gradient pp. 221-225

P. Ciais, J. Tan, X. Wang, C. Roedenbeck, F. Chevallier, S.-L. Piao, R. Moriarty, G. Broquet, C. Quéré, J. G. Canadell, S. Peng, B. Poulter, Z. Liu and P. Tans

RETRACTED ARTICLE: Complex societies precede moralizing gods throughout world history pp. 226-229

Harvey Whitehouse, Pieter François, Patrick E. Savage, Thomas E. Currie, Kevin C. Feeney, Enrico Cioni, Rosalind Purcell, Robert M. Ross, Jennifer Larson, John Baines, Barend Haar, Alan Covey and Peter Turchin

A potassium channel β-subunit couples mitochondrial electron transport to sleep pp. 230-234

Anissa Kempf, Seoho M. Song, Clifford B. Talbot and Gero Miesenböck

Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH+ pp. 235-239

Chee-Huat Linus Eng, Michael Lawson, Qian Zhu, Ruben Dries, Noushin Koulena, Yodai Takei, Jina Yun, Christopher Cronin, Christoph Karp, Guo-Cheng Yuan and Long Cai

TMK1-mediated auxin signalling regulates differential growth of the apical hook pp. 240-243

Min Cao, Rong Chen, Pan Li, Yongqiang Yu, Rui Zheng, Danfeng Ge, Wei Zheng, Xuhui Wang, Yangtao Gu, Zuzana Gelová, Jiří Friml, Heng Zhang, Renyi Liu, Jun He and Tongda Xu

HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation pp. 244-248

Ravindra K. Gupta, Sultan Abdul-Jawad, Laura E. McCoy, Hoi Ping Mok, Dimitra Peppa, Maria Salgado, Javier Martinez-Picado, Monique Nijhuis, Annemarie M. J. Wensing, Helen Lee, Paul Grant, Eleni Nastouli, Jonathan Lambert, Matthew Pace, Fanny Salasc, Christopher Monit, Andrew J. Innes, Luke Muir, Laura Waters, John Frater, Andrew M. L. Lever, Simon G. Edwards, Ian H. Gabriel and Eduardo Olavarria

A NIK–SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB pp. 249-253

Zixu Liu, Katrina B. Mar, Natasha W. Hanners, Sofya S. Perelman, Mohammed Kanchwala, Chao Xing, John W. Schoggins and Neal M. Alto

Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism pp. 254-258

Jiyoung Lee, Ali E. Yesilkanal, Joseph P. Wynne, Casey Frankenberger, Juan Liu, Jielin Yan, Mohamad Elbaz, Daniel C. Rabe, Felicia D. Rustandy, Payal Tiwari, Elizabeth A. Grossman, Peter C. Hart, Christie Kang, Sydney M. Sanderson, Jorge Andrade, Daniel K. Nomura, Marcelo G. Bonini, Jason W. Locasale and Marsha Rich Rosner

PTC-bearing mRNA elicits a genetic compensation response via Upf3a and COMPASS components pp. 259-263

Zhipeng Ma, Peipei Zhu, Hui Shi, Liwei Guo, Qinghe Zhang, Yanan Chen, Shuming Chen, Zhe Zhang, Jinrong Peng and Jun Chen

Mayfly invasion, ripples in the sky and a jumping squid: Nature’s photo competition pp. 265-267

Jack Leeming

A billion dots of light pp. 270-270

Matt Thompson

2019, volume 568, articles 7750

Author Correction: A population of luminous accreting black holes with hidden mergers pp. E1-E1

Michael J. Koss, Laura Blecha, Phillip Bernhard, Chao-Ling Hung, Jessica R. Lu, Benny Trakhtenbrot, Ezequiel Treister, Anna Weigel, Lia F. Sartori, Richard Mushotzky, Kevin Schawinski, Claudio Ricci, Sylvain Veilleux and David B. Sanders

Publisher Correction: Glacial expansion of oxygen-depleted seawater in the eastern tropical Pacific pp. E2-E2

Babette A. A. Hoogakker, Zunli Lu, Natalie Umling, Luke Jones, Xiaoli Zhou, Rosalind E. M. Rickaby, Robert Thunell, Olivier Cartapanis and Eric Galbraith

Duke University’s huge misconduct fine is a reminder to reward rigour pp. 7-7

Arturo Casadevall

What Thailand’s long-awaited election could mean for science pp. 13-14

Smriti Mallapaty

North Korean physicists forge rare exchange deal with Italian university pp. 14-15

Alison Abbott

Air pollution science under siege at US environment agency pp. 15-16

Jeff Tollefson

Gravitational-wave hunt restarts — with a quantum boost pp. 16-17

Davide Castelvecchi

Conservation groups urge fair trial for jailed Iranian researchers pp. 17-18

Michele Catanzaro

Tree sleuths are using DNA tests and machine vision to crack timber crimes pp. 19-21

Aisling Irwin

The nuclear sins of the Soviet Union live on in Kazakhstan pp. 22-24

Wudan Yan

Restoring natural forests is the best way to remove atmospheric carbon pp. 25-28

Simon L. Lewis, Charlotte E. Wheeler, Edward T. A. Mitchard and Alexander Koch

The hidden influencers who code our world pp. 30-31

Li Gong

The climate revolution that almost was, the science of magic, and sleep disorders examined: Books in brief pp. 31-31

Barbara Kiser

From counting with stones to artificial intelligence: the story of calculus pp. 32-32

Anil Ananthaswamy

Dam development: value both wetlands and hydropower pp. 33-33

John H. Matthews

Border-wall dollars would double US cancer-research budget pp. 33-33

Thomas E. DeCoursey

Hydropower: don’t waste climate money on more dams pp. 33-33

Philip Fearnside

Knowing and doing — conservation charities must spend wisely pp. 33-33

Hollie Booth

Ukraine — science showing green shoots of recovery pp. 33-33

George Gamota

Wallace Smith Broecker (1931-2019) pp. 34-34

Peter de Menocal

Snapshots of vibrating molecules pp. 36-37

Eric C. Le Ru

New interactions seen in an ultracold gas pp. 37-38

Georg M. Bruun

How climate and human activity shape a mountain ecosystem pp. 38-39

Robert M. Pringle

Elusive microbe that consumes ethane found under the sea pp. 40-41

Stephen W. Ragsdale

Coral symbiosis is a three-player game pp. 41-42

Thomas A. Richards and John P. McCutcheon

Structural variation in the gut microbiome associates with host health pp. 43-48

David Zeevi, Tal Korem, Anastasia Godneva, Noam Bar, Alexander Kurilshikov, Maya Lotan-Pompan, Adina Weinberger, Jingyuan Fu, Cisca Wijmenga, Alexandra Zhernakova and Eran Segal

Visualizing DNA folding and RNA in embryos at single-cell resolution pp. 49-54

Leslie J. Mateo, Sedona E. Murphy, Antonina Hafner, Isaac S. Cinquini, Carly A. Walker and Alistair N. Boettiger

The unexpected surface of asteroid (101955) Bennu pp. 55-60

D. S. Lauretta, D. N. DellaGiustina, C. A. Bennett, D. R. Golish, K. J. Becker, S. S. Balram-Knutson, O. S. Barnouin, T. L. Becker, W. F. Bottke, W. V. Boynton, H. Campins, B. E. Clark, H. C. Connolly, C. Y. Drouet d’Aubigny, J. P. Dworkin, J. P. Emery, H. L. Enos, V. E. Hamilton, C. W. Hergenrother, E. S. Howell, M. R. M. Izawa, H. H. Kaplan, M. C. Nolan, B. Rizk, H. L. Roper, D. J. Scheeres, P. H. Smith, K. J. Walsh and C. W. V. Wolner

Observation of fermion-mediated interactions between bosonic atoms pp. 61-64

B. J. DeSalvo, Krutik Patel, Geyue Cai and Cheng Chin

Nonreciprocal control and cooling of phonon modes in an optomechanical system pp. 65-69

H. Xu, Luyao Jiang, A. A. Clerk and J. G. E. Harris

Van der Waals contacts between three-dimensional metals and two-dimensional semiconductors pp. 70-74

Yan Wang, Jong Chan Kim, Ryan J. Wu, Jenny Martinez, Xiuju Song, Jieun Yang, Fang Zhao, Andre Mkhoyan, Hu Young Jeong and Manish Chhowalla

Attosecond angular streaking and tunnelling time in atomic hydrogen pp. 75-77

U. Satya Sainadh, Han Xu, Xiaoshan Wang, A. Atia-Tul-Noor, William C. Wallace, Nicolas Douguet, Alexander Bray, Igor Ivanov, Klaus Bartschat, Anatoli Kheifets, R. T. Sang and I. V. Litvinyuk

Visualizing vibrational normal modes of a single molecule with atomically confined light pp. 78-82

Joonhee Lee, Kevin T. Crampton, Nicholas Tallarida and V. Ara Apkarian

Mid-latitude net precipitation decreased with Arctic warming during the Holocene pp. 83-87

Cody C. Routson, Nicholas P. McKay, Darrell S. Kaufman, Michael P. Erb, Hugues Goosse, Bryan N. Shuman, Jessica R. Rodysill and Toby Ault

Climate–land-use interactions shape tropical mountain biodiversity and ecosystem functions pp. 88-92

Marcell K. Peters, Andreas Hemp, Tim Appelhans, Joscha N. Becker, Christina Behler, Alice Classen, Florian Detsch, Andreas Ensslin, Stefan W. Ferger, Sara B. Frederiksen, Friederike Gebert, Friederike Gerschlauer, Adrian Gütlein, Maria Helbig-Bonitz, Claudia Hemp, William J. Kindeketa, Anna Kühnel, Antonia V. Mayr, Ephraim Mwangomo, Christine Ngereza, Henry K. Njovu, Insa Otte, Holger Pabst, Marion Renner, Juliane Röder, Gemma Rutten, David Schellenberger Costa, Natalia Sierra-Cornejo, Maximilian G. R. Vollstädt, Hamadi I. Dulle, Connal D. Eardley, Kim M. Howell, Alexander Keller, Ralph S. Peters, Axel Ssymank, Victor Kakengi, Jie Zhang, Christina Bogner, Katrin Böhning-Gaese, Roland Brandl, Dietrich Hertel, Bernd Huwe, Ralf Kiese, Michael Kleyer, Yakov Kuzyakov, Thomas Nauss, Matthias Schleuning, Marco Tschapka, Markus Fischer and Ingolf Steffan-Dewenter

Chemosensory modulation of neural circuits for sodium appetite pp. 93-97

Sangjun Lee, Vineet Augustine, Yuan Zhao, Haruka Ebisu, Brittany Ho, Dong Kong and Yuki Oka

A gut-to-brain signal of fluid osmolarity controls thirst satiation pp. 98-102

Christopher A. Zimmerman, Erica L. Huey, Jamie S. Ahn, Lisa R. Beutler, Chan Lek Tan, Seher Kosar, Ling Bai, Yiming Chen, Timothy V. Corpuz, Linda Madisen, Hongkui Zeng and Zachary A. Knight

A widespread coral-infecting apicomplexan with chlorophyll biosynthesis genes pp. 103-107

Waldan K. Kwong, Javier Campo, Varsha Mathur, Mark J. A. Vermeij and Patrick J. Keeling

Anaerobic oxidation of ethane by archaea from a marine hydrocarbon seep pp. 108-111

Song-Can Chen, Niculina Musat, Oliver J. Lechtenfeld, Heidrun Paschke, Matthias Schmidt, Nedal Said, Denny Popp, Federica Calabrese, Hryhoriy Stryhanyuk, Ulrike Jaekel, Yong-Guan Zhu, Samantha B. Joye, Hans-Hermann Richnow, Friedrich Widdel and Florin Musat

CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape pp. 112-116

Mohamad Hamieh, Anton Dobrin, Annalisa Cabriolu, Sjoukje J. C. van der Stegen, Theodoros Giavridis, Jorge Mansilla-Soto, Justin Eyquem, Zeguo Zhao, Benjamin M. Whitlock, Matthew M. Miele, Zhuoning Li, Kristen M. Cunanan, Morgan Huse, Ronald C. Hendrickson, Xiuyan Wang, Isabelle Rivière and Michel Sadelain

Breast cancer cells rely on environmental pyruvate to shape the metastatic niche pp. 117-121

Ilaria Elia, Matteo Rossi, Steve Stegen, Dorien Broekaert, Ginevra Doglioni, Marit van Gorsel, Ruben Boon, Carmen Escalona-Noguero, Sophie Torrekens, Catherine Verfaillie, Erik Verbeken, Geert Carmeliet and Sarah-Maria Fendt

Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of natural products pp. 122-126

Bo Zhang, Kai Biao Wang, Wen Wang, Xin Wang, Fang Liu, Jiapeng Zhu, Jing Shi, Ling Yu Li, Hao Han, Kuang Xu, Hong Yun Qiao, Xiao Zhang, Rui Hua Jiao, Kendall N. Houk, Yong Liang, Ren Xiang Tan and Hui Ming Ge

Structure of the human LAT1–4F2hc heteromeric amino acid transporter complex pp. 127-130

Renhong Yan, Xin Zhao, Jianlin Lei and Qiang Zhou

11 ways to avert a data-storage disaster pp. 131-132

Jeffrey M. Perkel

Top tips for giving an engaging talk pp. 133-135

Virginia Gewin

How I was almost mistaken for a chocolatier pp. 135-135

Jamie Sugrue

Amped life pp. 138-138

John Cooper Hamilton