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2017, volume 546, articles 7660

Contesting the evidence for limited human lifespan pp. E6-E7

Nicholas J. L. Brown, Casper J. Albers and Stuart J. Ritchie

Dong et al. reply pp. E7-E7

Xiao Dong, Brandon Milholland and Jan Vijg

Many possible maximum lifespan trajectories pp. E8-E9

Bryan G. Hughes and Siegfried Hekimi

Dong et al. reply pp. E9-E10

Xiao Dong, Brandon Milholland and Jan Vijg

Is there evidence for a limit to human lifespan? pp. E11-E12

Maarten P. Rozing, Thomas B. L. Kirkwood and Rudi G. J. Westendorp

Dong et al. reply pp. E12-E12

Xiao Dong, Brandon Milholland and Jan Vijg

Questionable evidence for a limit to human lifespan pp. E13-E14

Adam Lenart and James W. Vaupel

Dong et al. reply pp. E14-E15

Xiao Dong, Brandon Milholland and Jan Vijg

Maximum human lifespan may increase to 125 years pp. E16-E17

Joop de Beer, Anastasios Bardoutsos and Fanny Janssen

Dong et al. reply pp. E21-E21

Xiao Dong, Brandon Milholland and Jan Vijg

Let science be a springboard for politics pp. 577-577

James Martin

Success of gravity-wave satellite paves way for three-craft mission pp. 583-584

Davide Castelvecchi

Scientists in limbo as US Supreme Court allows modified travel ban pp. 584-585

Sara Reardon

Overlooked water loss in plants could throw off climate models pp. 585-586

Heidi Ledford

Air guns used in offshore oil exploration can kill tiny marine life pp. 586-587

Jeff Tollefson

Modified viruses deliver death to antibiotic-resistant bacteria pp. 587-588

Sara Reardon

How quantum trickery can scramble cause and effect pp. 590-592

Philip Ball

Three years to safeguard our climate pp. 593-595

Christiana Figueres, Hans Joachim Schellnhuber, Gail Whiteman, Johan Rockström, Anthony Hobley and Stefan Rahmstorf

Astrobiology: Hunting aliens pp. 596-597

Ramin Skibba

Books in brief pp. 597-597

Barbara Kiser

Medicine: Heroes of global health pp. 598-598

Amy Maxmen

'Flammable ice' — extract with caution pp. 599-599

Haoran Dong and Guangming Zeng

Growing threat of urban waste dumps pp. 599-599

Huabo Duan, Jinhui Li and Gang Liu

Taxonomy: naming algae, fungi, plants pp. 599-599

Vicki A. Funk, Patrick Herendeen and Sandra Knapp

Taxonomy: use the red list as a registry pp. 599-600

Klaas-Douwe B. Dijkstra

Taxonomy: avoid extra bureaucracy pp. 600-600

Peter M. Hollingsworth

Taxonomy: retain scientific autonomy pp. 600-600

Markus Lambertz

Taxonomy: swallow the costly medicine pp. 600-600

John Buckeridge

Taxonomy: the IUBS responds pp. 600-600

Hiroyuki Takeda

Bibliometrics: An obituary for the impact factor pp. 600-600

Richard J. Roberts

A larger quantum alphabet pp. 602-603

Roberto Osellame

Predictions of virus spillover across species pp. 603-604

James O. Lloyd-Smith

A light-fuelled wave machine pp. 604-606

Yanlei Yu

Gut sensor halts viral attack pp. 606-608

Pedro H. V. Saavedra and Mohamed Lamkanfi

The fingerprints of reaction mechanisms pp. 608-609

Claire Vallance

Lymphatic detours for cancer pp. 609-610

Ayuko Hoshino and David Lyden

Homeostatic circuits selectively gate food cue responses in insular cortex pp. 611-616

Yoav Livneh, Rohan N. Ramesh, Christian R. Burgess, Kirsten M. Levandowski, Joseph C. Madara, Henning Fenselau, Glenn J. Goldey, Veronica E. Diaz, Nick Jikomes, Jon M. Resch, Bradford B. Lowell and Mark L. Andermann

Structure of a pre-catalytic spliceosome pp. 617-621

Clemens Plaschka, Pei-Chun Lin and Kiyoshi Nagai

On-chip generation of high-dimensional entangled quantum states and their coherent control pp. 622-626

Michael Kues, Christian Reimer, Piotr Roztocki, Luis Romero Cortés, Stefania Sciara, Benjamin Wetzel, Yanbing Zhang, Alfonso Cino, Sai T. Chu, Brent E. Little, David J. Moss, Lucia Caspani, José Azaña and Roberto Morandotti

Observation of three-component fermions in the topological semimetal molybdenum phosphide pp. 627-631

B. Q. Lv, Z.-L. Feng, Q.-N. Xu, X. Gao, J.-Z. Ma, L.-Y. Kong, P. Richard, Y.-B. Huang, V. N. Strocov, C. Fang, H.-M. Weng, Y.-G. Shi, T. Qian and H. Ding

Making waves in a photoactive polymer film pp. 632-636

Anne Helene Gelebart, Dirk Jan Mulder, Michael Varga, Andrew Konya, Ghislaine Vantomme, E. W. Meijer, Robin L. B. Selinger and Dirk J. Broer

Surface tension prevails over solute effect in organic-influenced cloud droplet activation pp. 637-641

Jurgita Ovadnevaite, Andreas Zuend, Ari Laaksonen, Kevin J. Sanchez, Greg Roberts, Darius Ceburnis, Stefano Decesari, Matteo Rinaldi, Natasha Hodas, Maria Cristina Facchini, John H. Seinfeld and Colin O’ Dowd

Hidden morphological diversity among early tetrapods pp. 642-645

Jason D. Pardo, Matt Szostakiwskyj, Per E. Ahlberg and Jason S. Anderson

Host and viral traits predict zoonotic spillover from mammals pp. 646-650

Kevin J. Olival, Parviez R. Hosseini, Carlos Zambrana-Torrelio, Noam Ross, Tiffany L. Bogich and Peter Daszak

Trans-kingdom mimicry underlies ribosome customization by a poxvirus kinase pp. 651-655

Sujata Jha, Madeline G. Rollins, Gabriele Fuchs, Dean J. Procter, Elizabeth A. Hall, Kira Cozzolino, Peter Sarnow, Jeffrey N. Savas and Derek Walsh

T cells from patients with Parkinson’s disease recognize α-synuclein peptides pp. 656-661

David Sulzer, Roy N. Alcalay, Francesca Garretti, Lucien Cote, Ellen Kanter, Julian Agin-Liebes, Christopher Liong, Curtis McMurtrey, William H. Hildebrand, Xiaobo Mao, Valina L. Dawson, Ted M. Dawson, Carla Oseroff, John Pham, John Sidney, Myles B. Dillon, Chelsea Carpenter, Daniela Weiskopf, Elizabeth Phillips, Simon Mallal, Bjoern Peters, April Frazier, Cecilia S. Lindestam Arlehamn and Alessandro Sette

Human fetal dendritic cells promote prenatal T-cell immune suppression through arginase-2 pp. 662-666

Naomi McGovern, Amanda Shin, Gillian Low, Donovan Low, Kaibo Duan, Leong Jing Yao, Rasha Msallam, Ivy Low, Nurhidaya Binte Shadan, Hermi R Sumatoh, Erin Soon, Josephine Lum, Esther Mok, Sandra Hubert, Peter See, Edwin Huang Kunxiang, Yie Hou Lee, Baptiste Janela, Mahesh Choolani, Citra Nurfarah Zaini Mattar, Yiping Fan, Tony Kiat Hon Lim, Dedrick Kok Hong Chan, Ker-Kan Tan, John Kit Chung Tam, Christopher Schuster, Adelheid Elbe-Bürger, Xiao-nong Wang, Venetia Bigley, Matthew Collin, Muzlifah Haniffa, Andreas Schlitzer, Michael Poidinger, Salvatore Albani, Anis Larbi, Evan W Newell, Jerry Kok Yen Chan and Florent Ginhoux

Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells pp. 667-670

Shu Zhu, Siyuan Ding, Penghua Wang, Zheng Wei, Wen Pan, Noah W. Palm, Yi Yang, Hua Yu, Hua-Bing Li, Geng Wang, Xuqiu Lei, Marcel R. de Zoete, Jun Zhao, Yunjiang Zheng, Haiwei Chen, Yujiao Zhao, Kellie A. Jurado, Ningguo Feng, Liang Shan, Yuval Kluger, Jun Lu, Clara Abraham, Erol Fikrig, Harry B. Greenberg and Richard A. Flavell

ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis pp. 671-675

Rohit Bose, Wouter R. Karthaus, Joshua Armenia, Wassim Abida, Phillip J. Iaquinta, Zeda Zhang, John Wongvipat, Elizabeth V. Wasmuth, Neel Shah, Patrick S. Sullivan, Michael G. Doran, Ping Wang, Anna Patruno, Yilin Zhao, Deyou Zheng, Nikolaus Schultz and Charles L. Sawyers

Whole-body imaging of lymphovascular niches identifies pre-metastatic roles of midkine pp. 676-680

David Olmeda, Daniela Cerezo-Wallis, Erica Riveiro-Falkenbach, Paula C. Pennacchi, Marta Contreras-Alcalde, Nuria Ibarz, Metehan Cifdaloz, Xavier Catena, Tonantzin G. Calvo, Estela Cañón, Direna Alonso-Curbelo, Javier Suarez, Lisa Osterloh, Osvaldo Graña, Francisca Mulero, Diego Megías, Marta Cañamero, Jorge L. Martínez-Torrecuadrada, Chandrani Mondal, Julie Di Martino, David Lora, Inés Martinez-Corral, J. Javier Bravo-Cordero, Javier Muñoz, Susana Puig, Pablo Ortiz-Romero, José L. Rodriguez-Peralto, Sagrario Ortega and María S. Soengas

Crystal structure of the potassium-importing KdpFABC membrane complex pp. 681-685

Ching-Shin Huang, Bjørn Panyella Pedersen and David L. Stokes

Correction: Corrigendum: CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses pp. 686-686

Benjamin Descours, Gaël Petitjean, José-Luis López-Zaragoza, Timothée Bruel, Raoul Raffel, Christina Psomas, Jacques Reynes, Christine Lacabaratz, Yves Levy, Olivier Schwartz, Jean Daniel Lelievre and Monsef Benkirane

Correction: Corrigendum: Dermatologist-level classification of skin cancer with deep neural networks pp. 686-686

Andre Esteva, Brett Kuprel, Roberto A. Novoa, Justin Ko, Susan M. Swetter, Helen M. Blau and Sebastian Thrun

Correction: Corrigendum: Common genetic variation drives molecular heterogeneity in human iPSCs pp. 686-686

Helena Kilpinen, Angela Goncalves, Andreas Leha, Vackar Afzal, Kaur Alasoo, Sofie Ashford, Sendu Bala, Dalila Bensaddek, Francesco Paolo Casale, Oliver J. Culley, Petr Danecek, Adam Faulconbridge, Peter W. Harrison, Annie Kathuria, Davis McCarthy, Shane A. McCarthy, Ruta Meleckyte, Yasin Memari, Nathalie Moens, Filipa Soares, Alice Mann, Ian Streeter, Chukwuma A. Agu, Alex Alderton, Rachel Nelson, Sarah Harper, Minal Patel, Alistair White, Sharad R. Patel, Laura Clarke, Reena Halai, Christopher M. Kirton, Anja Kolb-Kokocinski, Philip Beales, Ewan Birney, Davide Danovi, Angus I. Lamond, Willem H. Ouwehand, Ludovic Vallier, Fiona M. Watt, Richard Durbin, Oliver Stegle and Daniel J. Gaffney

The architecture of structured DNA pp. 687-689

XiaoZhi Lim

Networking: High fliers pp. 691-692

Amber Dance

Turning point: Tumour tactician pp. 693-693

Virginia Gewin

Gender bias: Citation lag in astronomy pp. 693-693

Virginia Gewin

Jurassic Jaws Jones pp. 696-696

Hal Y. Zhang

2017, volume 546, articles 7659

Effects of a ketamine metabolite on synaptic NMDAR function pp. E1-E3

Kanzo Suzuki, Elena Nosyreva, Kevin W. Hunt, Ege T. Kavalali and Lisa M. Monteggia

Zanos et al. reply pp. E4-E5

Panos Zanos, Ruin Moaddel, Patrick J. Morris, Polymnia Georgiou, Jonathan Fischell, Greg I. Elmer, Manickavasagom Alkondon, Peixiong Yuan, Heather J. Pribut, Nagendra S. Singh, Katina S. S. Dossou, Yuhong Fang, Xi-Ping Huang, Cheryl L. Mayo, Edson X. Albuquerque, Scott M. Thompson, Craig J. Thomas, Carlos A. Zarate and Todd D. Gould

Eardrum regeneration: membrane repair pp. S5-S5

David Holmes

Marching to a new beat pp. S6-S7

David Holmes

Botany: He made plants a profession pp. 472-473

Jim Endersby

Data-sharing for indigenous peoples pp. 474-474

Emma Kowal, Bastien Llamas and Sarah Tishkoff

Religion's openness towards science pp. 474-474

Frank W. Nicholas

Fight fake reagents with digital tools pp. 474-474

Don Gunasekera

Document India's floral biodiversity pp. 474-474

Kamaljit S. Bawa and R. Ganesan

These retinas are made for walkin' pp. 476-477

Jonathan B. Demb and Damon A. Clark

No sign of asymmetry in the strong force pp. 477-478

Alexandru Florin Dobrin

A spoonful of sugar could be the medicine pp. 479-480

Hea-Jin Jung and Eric G. Pamer

The feline line pp. 480-480

Luíseach Nic Eoin

Interactions propel a magnetic dance pp. 481-482

Lindsay J. LeBlanc

Synapses pruned in lupus pp. 482-483

Sarah McGlasson and David Hunt

Clouds unfazed by haze pp. 483-484

Bjorn Stevens

Strong constraints on aerosol–cloud interactions from volcanic eruptions pp. 485-491

Florent F. Malavelle, Jim M. Haywood, Andy Jones, Andrew Gettelman, Lieven Clarisse, Sophie Bauduin, Richard P. Allan, Inger Helene H. Karset, Jón Egill Kristjánsson, Lazaros Oreopoulos, Nayeong Cho, Dongmin Lee, Nicolas Bellouin, Olivier Boucher, Daniel P. Grosvenor, Ken S. Carslaw, Sandip Dhomse, Graham W. Mann, Anja Schmidt, Hugh Coe, Margaret E. Hartley, Mohit Dalvi, Adrian A. Hill, Ben T. Johnson, Colin E. Johnson, Jeff R. Knight, Fiona M. O’Connor, Daniel G. Partridge, Philip Stier, Gunnar Myhre, Steven Platnick, Graeme L. Stephens, Hanii Takahashi and Thorvaldur Thordarson

A retinal code for motion along the gravitational and body axes pp. 492-497

Shai Sabbah, John A. Gemmer, Ananya Bhatia-Lin, Gabrielle Manoff, Gabriel Castro, Jesse K. Siegel, Nathan Jeffery and David M. Berson

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer pp. 498-503

Sushrut Kamerkar, Valerie S. LeBleu, Hikaru Sugimoto, Sujuan Yang, Carolina F. Ruivo, Sonia A. Melo, J. Jack Lee and Raghu Kalluri

Structure of the human multidrug transporter ABCG2 pp. 504-509

Nicholas M. I. Taylor, Ioannis Manolaridis, Scott M. Jackson, Julia Kowal, Henning Stahlberg and Kaspar P. Locher

A massive, dead disk galaxy in the early Universe pp. 510-513

Sune Toft, Johannes Zabl, Johan Richard, Anna Gallazzi, Stefano Zibetti, Moire Prescott, Claudio Grillo, Allison W. S. Man, Nicholas Y. Lee, Carlos Gómez-Guijarro, Mikkel Stockmann, Georgios Magdis and Charles L. Steinhardt

A giant planet undergoing extreme-ultraviolet irradiation by its hot massive-star host pp. 514-518

B. Scott Gaudi, Keivan G. Stassun, Karen A. Collins, Thomas G. Beatty, George Zhou, David W. Latham, Allyson Bieryla, Jason D. Eastman, Robert J. Siverd, Justin R. Crepp, Erica J. Gonzales, Daniel J. Stevens, Lars A. Buchhave, Joshua Pepper, Marshall C. Johnson, Knicole D. Colon, Eric L. N. Jensen, Joseph E. Rodriguez, Valerio Bozza, Sebastiano Calchi Novati, Giuseppe D’Ago, Mary T. Dumont, Tyler Ellis, Clement Gaillard, Hannah Jang-Condell, David H. Kasper, Akihiko Fukui, Joao Gregorio, Ayaka Ito, John F. Kielkopf, Mark Manner, Kyle Matt, Norio Narita, Thomas E. Oberst, Phillip A. Reed, Gaetano Scarpetta, Denice C. Stephens, Rex R. Yeigh, Roberto Zambelli, B. J. Fulton, Andrew W. Howard, David J. James, Matthew Penny, Daniel Bayliss, Ivan A. Curtis, D. L. DePoy, Gilbert A. Esquerdo, Andrew Gould, Michael D. Joner, Rudolf B. Kuhn, Jonathan Labadie-Bartz, Michael B. Lund, Jennifer L. Marshall, Kim K. McLeod, Richard W. Pogge, Howard Relles, Christopher Stockdale, T. G. Tan, Mark Trueblood and Patricia Trueblood

Microscopy of the interacting Harper–Hofstadter model in the two-body limit pp. 519-523

M. Eric Tai, Alexander Lukin, Matthew Rispoli, Robert Schittko, Tim Menke, Dan Borgnia, Philipp M. Preiss, Fabian Grusdt, Adam M. Kaufman and Markus Greiner

Improved maize reference genome with single-molecule technologies pp. 524-527

Yinping Jiao, Paul Peluso, Jinghua Shi, Tiffany Liang, Michelle C. Stitzer, Bo Wang, Michael S. Campbell, Joshua C. Stein, Xuehong Wei, Chen-Shan Chin, Katherine Guill, Michael Regulski, Sunita Kumari, Andrew Olson, Jonathan Gent, Kevin L. Schneider, Thomas K. Wolfgruber, Michael R. May, Nathan M. Springer, Eric Antoniou, W. Richard McCombie, Gernot G. Presting, Michael McMullen, Jeffrey Ross-Ibarra, R. Kelly Dawe, Alex Hastie, David R. Rank and Doreen Ware

Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist pp. 528-532

Caitlin N. Spaulding, Roger D. Klein, Ségolène Ruer, Andrew L. Kau, Henry L. Schreiber, Zachary T. Cusumano, Karen W. Dodson, Jerome S. Pinkner, Daved H. Fremont, James W. Janetka, Han Remaut, Jeffrey I. Gordon and Scott J. Hultgren

Multilineage communication regulates human liver bud development from pluripotency pp. 533-538

J. Gray Camp, Keisuke Sekine, Tobias Gerber, Henry Loeffler-Wirth, Hans Binder, Malgorzata Gac, Sabina Kanton, Jorge Kageyama, Georg Damm, Daniel Seehofer, Lenka Belicova, Marc Bickle, Rico Barsacchi, Ryo Okuda, Emi Yoshizawa, Masaki Kimura, Hiroaki Ayabe, Hideki Taniguchi, Takanori Takebe and Barbara Treutlein

Microglia-dependent synapse loss in type I interferon-mediated lupus pp. 539-543

Allison R. Bialas, Jessy Presumey, Abhishek Das, Cees E. van der Poel, Peter H. Lapchak, Luka Mesin, Gabriel Victora, George C. Tsokos, Christian Mawrin, Ronald Herbst and Michael C. Carroll

Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge pp. 544-548

Matthew J. Emmett, Hee-Woong Lim, Jennifer Jager, Hannah J. Richter, Marine Adlanmerini, Lindsey C. Peed, Erika R. Briggs, David J. Steger, Tao Ma, Carrie A. Sims, Joseph A. Baur, Liming Pei, Kyoung-Jae Won, Patrick Seale, Zachary Gerhart-Hines and Mitchell A. Lazar

BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation pp. 549-553

Angela Bononi, Carlotta Giorgi, Simone Patergnani, David Larson, Kaitlyn Verbruggen, Mika Tanji, Laura Pellegrini, Valentina Signorato, Federica Olivetto, Sandra Pastorino, Masaki Nasu, Andrea Napolitano, Giovanni Gaudino, Paul Morris, Greg Sakamoto, Laura K. Ferris, Alberto Danese, Andrea Raimondi, Carlo Tacchetti, Shafi Kuchay, Harvey I. Pass, El Bachir Affar, Haining Yang, Paolo Pinton and Michele Carbone

PTEN counteracts FBXL2 to promote IP3R3- and Ca2+-mediated apoptosis limiting tumour growth pp. 554-558

Shafi Kuchay, Carlotta Giorgi, Daniele Simoneschi, Julia Pagan, Sonia Missiroli, Anita Saraf, Laurence Florens, Michael P. Washburn, Ana Collazo-Lorduy, Mireia Castillo-Martin, Carlos Cordon-Cardo, Said M. Sebti, Paolo Pinton and Michele Pagano

Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage pp. 559-563

Stefano Stella, Pablo Alcón and Guillermo Montoya

Addendum: The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease pp. 564-564

Jeff Sevigny, Ping Chiao, Thierry Bussière, Paul H. Weinreb, Leslie Williams, Marcel Maier, Robert Dunstan, Stephen Salloway, Tianle Chen, Yan Ling, John O’Gorman, Fang Qian, Mahin Arastu, Mingwei Li, Sowmya Chollate, Melanie S. Brennan, Omar Quintero-Monzon, Robert H. Scannevin, H. Moore Arnold, Thomas Engber, Kenneth Rhodes, James Ferrero, Yaming Hang, Alvydas Mikulskis, Jan Grimm, Christoph Hock, Roger M. Nitsch and Alfred Sandrock

Sustainability: A greener culture pp. 565-567

Julia Rosen

Memories to come pp. 570-570

Paul Alex Gray

2017, volume 546, articles 7658

Patience for patients pp. S1-S3

Neil Savage

Let Trump claim a better deal on climate pp. 329-329

Elliot Diringer

Eye-opening picture of fetal immune system emerges pp. 335-336

Heidi Ledford

United States revives space-policy council after 24-year absence pp. 337-337

Alexandra Witze

US mental-health agency’s push for basic research has slashed support for clinical trials pp. 339-339

Sara Reardon

Bats are global reservoir for deadly coronaviruses pp. 340-340

Amy Maxmen

The ‘time machine’ reconstructing ancient Venice’s social networks pp. 341-344

Alison Abbott

Fight the silencing of gun research pp. 345-347

David Hemenway

Natural history: Thoreau's debt to Darwin pp. 349-350

Randall Fuller

Neuroscience: How music meets mind pp. 351-351

Elizabeth Hellmuth Margulis

Publishing: Journals could share peer-review data pp. 352-352

Flaminio Squazzoni, Francisco Grimaldo and Ana Marušić

Tissue engineering: NIH competition to create 'eye in a dish' pp. 352-352

Paul A. Sieving

Conservation: Pay countries to stop whaling pp. 352-352

Shunsuke Managi and Mihoko Wakamatsu

Development: Sustainability and resilience differ pp. 352-352

Thomas Elmqvist

Junior scientists: Senior scientists as allies for equity pp. 352-352

Christina Simkanin and Alison Cawood

Wireless power on the move pp. 354-355

Geoffroy Lerosey

Molecular mapping of Zika spread pp. 355-356

Michael Worobey

Division enzyme regulates metabolism pp. 357-358

Abigail S. Krall and Heather R. Christofk

How to suck like an octopus pp. 358-359

Jonathan J. Wilker

A decade of shared genomic associations pp. 360-361

Teri A. Manolio

Local metabolites linked to memory pp. 361-362

L. Ashley Watson and Li-Huei Tsai

Damming the rivers of the Amazon basin pp. 363-369

Edgardo M. Latrubesse, Eugenio Y. Arima, Thomas Dunne, Edward Park, Victor R. Baker, Fernando M. d’Horta, Charles Wight, Florian Wittmann, Jansen Zuanon, Paul A. Baker, Camila C. Ribas, Richard B. Norgaard, Naziano Filizola, Atif Ansar, Bent Flyvbjerg and Jose C. Stevaux

Common genetic variation drives molecular heterogeneity in human iPSCs pp. 370-375

Helena Kilpinen, Angela Goncalves, Andreas Leha, Vackar Afzal, Kaur Alasoo, Sofie Ashford, Sendu Bala, Dalila Bensaddek, Francesco Paolo Casale, Oliver J. Culley, Petr Danecek, Adam Faulconbridge, Peter W. Harrison, Annie Kathuria, Davis McCarthy, Shane A. McCarthy, Ruta Meleckyte, Yasin Memari, Nathalie Moens, Filipa Soares, Alice Mann, Ian Streeter, Chukwuma A. Agu, Alex Alderton, Rachel Nelson, Sarah Harper, Minal Patel, Alistair White, Sharad R. Patel, Laura Clarke, Reena Halai, Christopher M. Kirton, Anja Kolb-Kokocinski, Philip Beales, Ewan Birney, Davide Danovi, Angus I. Lamond, Willem H. Ouwehand, Ludovic Vallier, Fiona M. Watt, Richard Durbin, Oliver Stegle and Daniel J. Gaffney

A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis pp. 376-380

Ujjini H. Manjunatha, Sumiti Vinayak, Jennifer A. Zambriski, Alexander T. Chao, Tracy Sy, Christian G. Noble, Ghislain M. C. Bonamy, Ravinder R. Kondreddi, Bin Zou, Peter Gedeck, Carrie F. Brooks, Gillian T. Herbert, Adam Sateriale, Jayesh Tandel, Susan Noh, Suresh B. Lakshminarayana, Siau H. Lim, Laura B. Goodman, Christophe Bodenreider, Gu Feng, Lijun Zhang, Francesca Blasco, Juergen Wagner, F. Joel Leong, Boris Striepen and Thierry T. Diagana

Acetyl-CoA synthetase regulates histone acetylation and hippocampal memory pp. 381-386

Philipp Mews, Greg Donahue, Adam M. Drake, Vincent Luczak, Ted Abel and Shelley L. Berger

Robust wireless power transfer using a nonlinear parity–time-symmetric circuit pp. 387-390

Sid Assawaworrarit, Xiaofang Yu and Shanhui Fan

Slush-like polar structures in single-crystal relaxors pp. 391-395

Hiroyuki Takenaka, Ilya Grinberg, Shi Liu and Andrew M. Rappe

A wet-tolerant adhesive patch inspired by protuberances in suction cups of octopi pp. 396-400

Sangyul Baik, Da Wan Kim, Youngjin Park, Tae-Jin Lee, Suk Ho Bhang and Changhyun Pang

Genomic epidemiology reveals multiple introductions of Zika virus into the United States pp. 401-405

Nathan D. Grubaugh, Jason T. Ladner, Moritz U. G. Kraemer, Gytis Dudas, Amanda L. Tan, Karthik Gangavarapu, Michael R. Wiley, Stephen White, Julien Thézé, Diogo M. Magnani, Karla Prieto, Daniel Reyes, Andrea M. Bingham, Lauren M. Paul, Refugio Robles-Sikisaka, Glenn Oliveira, Darryl Pronty, Carolyn M. Barcellona, Hayden C. Metsky, Mary Lynn Baniecki, Kayla G. Barnes, Bridget Chak, Catherine A. Freije, Adrianne Gladden-Young, Andreas Gnirke, Cynthia Luo, Bronwyn MacInnis, Christian B. Matranga, Daniel J. Park, James Qu, Stephen F. Schaffner, Christopher Tomkins-Tinch, Kendra L. West, Sarah M. Winnicki, Shirlee Wohl, Nathan L. Yozwiak, Joshua Quick, Joseph R. Fauver, Kamran Khan, Shannon E. Brent, Robert C. Reiner, Paola N. Lichtenberger, Michael J. Ricciardi, Varian K. Bailey, David I. Watkins, Marshall R. Cone, Edgar W. Kopp, Kelly N. Hogan, Andrew C. Cannons, Reynald Jean, Andrew J. Monaghan, Robert F. Garry, Nicholas J. Loman, Nuno R. Faria, Mario C. Porcelli, Chalmers Vasquez, Elyse R. Nagle, Derek A. T. Cummings, Danielle Stanek, Andrew Rambaut, Mariano Sanchez-Lockhart, Pardis C. Sabeti, Leah D. Gillis, Scott F. Michael, Trevor Bedford, Oliver G. Pybus, Sharon Isern, Gustavo Palacios and Kristian G. Andersen

Establishment and cryptic transmission of Zika virus in Brazil and the Americas pp. 406-410

N. R. Faria, J. Quick, I.M. Claro, J. Thézé, J. G. de Jesus, M. Giovanetti, M. U. G. Kraemer, S. C. Hill, A. Black, A. C. da Costa, L. C. Franco, S. P. Silva, C.-H. Wu, J. Raghwani, S. Cauchemez, L. du Plessis, M. P. Verotti, W. K. de Oliveira, E. H. Carmo, G. E. Coelho, A. C. F. S. Santelli, L. C. Vinhal, C. M. Henriques, J. T. Simpson, M. Loose, K. G. Andersen, N. D. Grubaugh, S. Somasekar, C. Y. Chiu, J. E. Muñoz-Medina, C. R. Gonzalez-Bonilla, C. F. Arias, L. L. Lewis-Ximenez, S. A. Baylis, A. O. Chieppe, S. F. Aguiar, C. A. Fernandes, P. S. Lemos, B. L. S. Nascimento, H. A. O. Monteiro, I. C. Siqueira, M. G. de Queiroz, T. R. de Souza, J. F. Bezerra, M. R. Lemos, G. F. Pereira, D. Loudal, L. C. Moura, R. Dhalia, R. F. França, T. Magalhães, E. T. Marques, T. Jaenisch, G. L. Wallau, M. C. de Lima, V. Nascimento, E. M. de Cerqueira, M. M. de Lima, D. L. Mascarenhas, J. P. Moura Neto, A. S. Levin, T. R. Tozetto-Mendoza, S. N. Fonseca, M. C. Mendes-Correa, F. P. Milagres, A. Segurado, E. C. Holmes, A. Rambaut, T. Bedford, M. R. T. Nunes, E. C. Sabino, L. C. J. Alcantara, N. J. Loman and O. G. Pybus

Zika virus evolution and spread in the Americas pp. 411-415

Hayden C. Metsky, Christian B. Matranga, Shirlee Wohl, Stephen F. Schaffner, Catherine A. Freije, Sarah M. Winnicki, Kendra West, James Qu, Mary Lynn Baniecki, Adrianne Gladden-Young, Aaron E. Lin, Christopher H. Tomkins-Tinch, Simon H. Ye, Daniel J. Park, Cynthia Y. Luo, Kayla G. Barnes, Rickey R. Shah, Bridget Chak, Giselle Barbosa-Lima, Edson Delatorre, Yasmine R. Vieira, Lauren M. Paul, Amanda L. Tan, Carolyn M. Barcellona, Mario C. Porcelli, Chalmers Vasquez, Andrew C. Cannons, Marshall R. Cone, Kelly N. Hogan, Edgar W. Kopp, Joshua J. Anzinger, Kimberly F. Garcia, Leda A. Parham, Rosa M. Gélvez Ramírez, Maria C. Miranda Montoya, Diana P. Rojas, Catherine M. Brown, Scott Hennigan, Brandon Sabina, Sarah Scotland, Karthik Gangavarapu, Nathan D. Grubaugh, Glenn Oliveira, Refugio Robles-Sikisaka, Andrew Rambaut, Lee Gehrke, Sandra Smole, M. Elizabeth Halloran, Luis Villar, Salim Mattar, Ivette Lorenzana, Jose Cerbino-Neto, Clarissa Valim, Wim Degrave, Patricia T. Bozza, Andreas Gnirke, Kristian G. Andersen, Sharon Isern, Scott F. Michael, Fernando A. Bozza, Thiago M. L. Souza, Irene Bosch, Nathan L. Yozwiak, Bronwyn L. MacInnis and Pardis C. Sabeti

Principles of early human development and germ cell program from conserved model systems pp. 416-420

Toshihiro Kobayashi, Haixin Zhang, Walfred W. C. Tang, Naoko Irie, Sarah Withey, Doris Klisch, Anastasiya Sybirna, Sabine Dietmann, David A. Contreras, Robert Webb, Cinzia Allegrucci, Ramiro Alberio and M. Azim Surani

Stability and function of regulatory T cells expressing the transcription factor T-bet pp. 421-425

Andrew G. Levine, Alejandra Mendoza, Saskia Hemmers, Bruno Moltedo, Rachel E. Niec, Michail Schizas, Beatrice E. Hoyos, Ekaterina V. Putintseva, Ashutosh Chaudhry, Stanislav Dikiy, Sho Fujisawa, Dmitriy M. Chudakov, Piper M. Treuting and Alexander Y. Rudensky

The metabolic function of cyclin D3–CDK6 kinase in cancer cell survival pp. 426-430

Haizhen Wang, Brandon N. Nicolay, Joel M. Chick, Xueliang Gao, Yan Geng, Hong Ren, Hui Gao, Guizhi Yang, Juliet A. Williams, Jan M. Suski, Mark A. Keibler, Ewa Sicinska, Ulrike Gerdemann, W. Nicholas Haining, Thomas M. Roberts, Kornelia Polyak, Steven P. Gygi, Nicholas J. Dyson and Piotr Sicinski

Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance pp. 431-435

Sydney M. Shaffer, Margaret C. Dunagin, Stefan R. Torborg, Eduardo A. Torre, Benjamin Emert, Clemens Krepler, Marilda Beqiri, Katrin Sproesser, Patricia A. Brafford, Min Xiao, Elliott Eggan, Ioannis N. Anastopoulos, Cesar A. Vargas-Garcia, Abhyudai Singh, Katherine L. Nathanson, Meenhard Herlyn and Arjun Raj

Structural basis of CRISPR–SpyCas9 inhibition by an anti-CRISPR protein pp. 436-439

Dong De, Minghui Guo, Sihan Wang, Yuwei Zhu, Shuo Wang, Zhi Xiong, Jianzheng Yang, Zengliang Xu and Zhiwei Huang

Correction: Corrigendum: MC4R-dependent suppression of appetite by bone-derived lipocalin 2 pp. 440-440

Ioanna Mosialou, Steven Shikhel, Jian-Min Liu, Antonio Maurizi, Na Luo, Zhenyan He, Yiru Huang, Haihong Zong, Richard A. Friedman, Jonathan Barasch, Patricia Lanzano, Liyong Deng, Rudolph L. Leibel, Mishaela Rubin, Thomas Nickolas, Wendy Chung, Lori M. Zeltser, Kevin W. Williams, Jeffrey E. Pessin and Stavroula Kousteni

Salary negotiation: Get what you seek pp. 441-442

Eryn Brown

Plot your course pp. 443-443

Nathan L. Vanderford

Custom-made pp. 446-446

Cassandra Khaw

2017, volume 546, articles 7657

We need a science of philanthropy pp. 187-187

Caroline Fiennes

Italy rebuked for failure to prevent olive-tree tragedy pp. 193-194

Alison Abbott

NASA’s dark-energy probe faces cost crisis pp. 195-195

Alexandra Witze

AI summit aims to help world’s poorest pp. 196-197

Declan Butler

Romania’s science reforms prompt boycott pp. 197-197

Inga Vesper

Trump pulls United States out of Paris climate agreement pp. 198-198

Jeff Tollefson

The mathematicians who want to save democracy pp. 200-202

Carrie Arnold

The G20 must govern the shift to low-carbon energy pp. 203-205

Andreas Goldthau

Influenza: A viral world war pp. 207-208

Tilli Tansey

Cryptography: The codes that got away pp. 208-209

Andrew Robinson

Books in brief pp. 209-209

Barbara Kiser

Heritage status could safeguard fossil beds pp. 210-210

Hong Yang, Mingguo Ma and Roger J Flower

A rescue package for imperilled collection pp. 210-210

Theodore J. Bornhorst, Christopher J. Poulsen and Rodney C. Ewing

Rules for new species from live specimens pp. 210-210

Vazrick Nazari and Douglas Yanega

Springer Nature's reply on fake review pp. 210-210

Tamara Welschot

Help to make food go further in Egypt pp. 210-210

Jeremy Nathans

On the origin of our species pp. 212-214

Chris Stringer and Julia Galway-Witham

One ring to multiplex them all pp. 214-215

Victor Torres-Company

RNA repeats put a freeze on cells pp. 215-216

David W. Sanders and Clifford P. Brangwynne

Magnetism in flatland pp. 216-217

Nitin Samarth

Differences can hold populations together pp. 218-219

David N. Reznick and Joseph Travis

Cracking the palaeoclimate code pp. 219-220

Stephen Meyers

Flavour-changing neutral currents making and breaking the standard model pp. 221-226

F. Archilli, M.-O. Bettler, P. Owen and K. A. Petridis

A challenge to lepton universality in B-meson decays pp. 227-233

Gregory Ciezarek, Manuel Franco Sevilla, Brian Hamilton, Robert Kowalewski, Thomas Kuhr, Vera Lüth and Yutaro Sato

Nutrient acquisition strategies of mammalian cells pp. 234-242

Wilhelm Palm and Craig B. Thompson

RNA phase transitions in repeat expansion disorders pp. 243-247

Ankur Jain and Ronald D. Vale

Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein pp. 248-253

Yan Zhang, Bingfa Sun, Dan Feng, Hongli Hu, Matthew Chu, Qianhui Qu, Jeffrey T. Tarrasch, Shane Li, Tong Sun Kobilka, Brian K. Kobilka and Georgios Skiniotis

Crystal structure of the GLP-1 receptor bound to a peptide agonist pp. 254-258

Ali Jazayeri, Mathieu Rappas, Alastair J. H. Brown, James Kean, James C. Errey, Nathan J. Robertson, Cédric Fiez-Vandal, Stephen P. Andrews, Miles Congreve, Andrea Bortolato, Jonathan S. Mason, Asma H. Baig, Iryna Teobald, Andrew S. Doré, Malcolm Weir, Robert M. Cooke and Fiona H. Marshall

Structure of the full-length glucagon class B G-protein-coupled receptor pp. 259-264

Haonan Zhang, Anna Qiao, Dehua Yang, Linlin Yang, Antao Dai, Chris de Graaf, Steffen Reedtz-Runge, Venkatasubramanian Dharmarajan, Hui Zhang, Gye Won Han, Thomas D. Grant, Raymond G. Sierra, Uwe Weierstall, Garrett Nelson, Wei Liu, Yanhong Wu, Limin Ma, Xiaoqing Cai, Guangyao Lin, Xiaoai Wu, Zhi Geng, Yuhui Dong, Gaojie Song, Patrick R. Griffin, Jesper Lau, Vadim Cherezov, Huaiyu Yang, Michael A. Hanson, Raymond C. Stevens, Qiang Zhao, Hualiang Jiang, Ming-Wei Wang and Beili Wu

Discovery of intrinsic ferromagnetism in two-dimensional van der Waals crystals pp. 265-269

Cheng Gong, Lin Li, Zhenglu Li, Huiwen Ji, Alex Stern, Yang Xia, Ting Cao, Wei Bao, Chenzhe Wang, Yuan Wang, Z. Q. Qiu, R. J. Cava, Steven G. Louie, Jing Xia and Xiang Zhang

Layer-dependent ferromagnetism in a van der Waals crystal down to the monolayer limit pp. 270-273

Bevin Huang, Genevieve Clark, Efrén Navarro-Moratalla, Dahlia R. Klein, Ran Cheng, Kyle L. Seyler, Ding Zhong, Emma Schmidgall, Michael A. McGuire, David H. Cobden, Wang Yao, Di Xiao, Pablo Jarillo-Herrero and Xiaodong Xu

Microresonator-based solitons for massively parallel coherent optical communications pp. 274-279

Pablo Marin-Palomo, Juned N. Kemal, Maxim Karpov, Arne Kordts, Joerg Pfeifle, Martin H. P. Pfeiffer, Philipp Trocha, Stefan Wolf, Victor Brasch, Miles H. Anderson, Ralf Rosenberger, Kovendhan Vijayan, Wolfgang Freude, Tobias J. Kippenberg and Christian Koos

Accelerated discovery of two crystal structure types in a complex inorganic phase field pp. 280-284

C. Collins, M. S. Dyer, M. J. Pitcher, G. F. S. Whitehead, M. Zanella, P. Mandal, J. B. Claridge, G. R. Darling and M. J. Rosseinsky

Frequency dependence limits divergent evolution by favouring rare immigrants over residents pp. 285-288

Daniel I. Bolnick and William E. Stutz

New fossils from Jebel Irhoud, Morocco and the pan-African origin of Homo sapiens pp. 289-292

Jean-Jacques Hublin, Abdelouahed Ben-Ncer, Shara E. Bailey, Sarah E. Freidline, Simon Neubauer, Matthew M. Skinner, Inga Bergmann, Adeline Le Cabec, Stefano Benazzi, Katerina Harvati and Philipp Gunz

The age of the hominin fossils from Jebel Irhoud, Morocco, and the origins of the Middle Stone Age pp. 293-296

Daniel Richter, Rainer Grün, Renaud Joannes-Boyau, Teresa E. Steele, Fethi Amani, Mathieu Rué, Paul Fernandes, Jean-Paul Raynal, Denis Geraads, Abdelouahed Ben-Ncer, Jean-Jacques Hublin and Shannon P. McPherron

Dynamic corticostriatal activity biases social bonding in monogamous female prairie voles pp. 297-301

Elizabeth A. Amadei, Zachary V. Johnson, Yong Jun Kwon, Aaron C. Shpiner, Varun Saravanan, Wittney D. Mays, Steven J. Ryan, Hasse Walum, Donald G. Rainnie, Larry J. Young and Robert C. Liu

The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition pp. 302-306

Gabriele Varano, Simon Raffel, Martina Sormani, Federica Zanardi, Silvia Lonardi, Christin Zasada, Laura Perucho, Valentina Petrocelli, Andrea Haake, Albert K. Lee, Mattia Bugatti, Ulrike Paul, Eelco Van Anken, Laura Pasqualucci, Raul Rabadan, Reiner Siebert, Stefan Kempa, Maurilio Ponzoni, Fabio Facchetti, Klaus Rajewsky and Stefano Casola

Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling pp. 307-311

Markus Brockmann, Vincent A. Blomen, Joppe Nieuwenhuis, Elmer Stickel, Matthijs Raaben, Onno B. Bleijerveld, A. F. Maarten Altelaar, Lucas T. Jae and Thijn R. Brummelkamp

Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators pp. 312-315

Gaojie Song, Dehua Yang, Yuxia Wang, Chris de Graaf, Qingtong Zhou, Shanshan Jiang, Kaiwen Liu, Xiaoqing Cai, Antao Dai, Guangyao Lin, Dongsheng Liu, Fan Wu, Yiran Wu, Suwen Zhao, Li Ye, Gye Won Han, Jesper Lau, Beili Wu, Michael A. Hanson, Zhi-Jie Liu, Ming-Wei Wang and Raymond C. Stevens

Correction: Corrigendum: Black hole growth in the early Universe is self-regulated and largely hidden from view pp. 316-316

Ezequiel Treister, Kevin Schawinski, Marta Volonteri, Priyamvada Natarajan and Eric Gawiser

Institutions: Small-school science pp. 317-319

Chris Woolston

Turning point: Reef inspector pp. 319-319

Virginia Gewin

Sparrowfall pp. 322-322

Robert Dawson

2017, volume 546, articles 7656

Crowd-based peer review can be good and fast pp. 9-9

Benjamin List

Trials of embryonic stem cells to launch in China pp. 15-16

David Cyranoski

UK election: science spending pledges overshadowed by Brexit pp. 16-17

Daniel Cressey

Mummy DNA unravels ancient Egyptians’ ancestry pp. 17-17

Traci Watson

Neutron stars set to open their heavy hearts pp. 18-18

Elizabeth Gibney

Trump budget would slash science programmes across government pp. 19-20

Sara Reardon, Jeff Tollefson, Alexandra Witze and Erin Ross

Biodiversity moves beyond counting species pp. 22-24

Rachel Cernansky

Taxonomy anarchy hampers conservation pp. 25-27

Stephen T. Garnett and Les Christidis

Govern land as a global commons pp. 28-29

Felix Creutzig

Genome editing: That's the way the CRISPR crumbles pp. 30-31

Nathaniel Comfort

Books in brief pp. 31-31

Barbara Kiser

Art: Under Mona Lisa's smile pp. 32-32

Philip Ball

Stamp out fake peer review pp. 33-33

Jian Gao and Tao Zhou

Value coordinating roles in research pp. 33-33

Eleanor M. Slade and Terhi Riutta

Lure young surgeons on to research tracks pp. 33-33

Daniel S. Alt

Stable identifiers for collection specimens pp. 33-33

Quentin Groom, Roger Hyam and Anton Güntsch

Rejuvenation study stirs old memories pp. 33-33

Matthis Krischel and Nils Hansson

Signalling under the microscope pp. 36-37

Ching-Ju Tsai, Joerg Standfuss and Robert M. Glaeser

Multi-molecular views of a stellar nursery pp. 37-39

Jennifer Wiseman and Marta Sewilo

An intracellular dance visualized pp. 39-40

Sang-Hee Shim

Functional materials at the flick of a switch pp. 40-41

Shriram Ramanathan

The self-cleansing ability of prehistoric air pp. 41-42

Michaela I. Hegglin

Sunflowers sequenced pp. 43-43

Orli G. Bahcall

Diversity breeds tolerance pp. 44-45

David G. Russell

Premature lambs grown in a bag pp. 45-46

Claire T. Roberts

Biodiversity pp. 47-47

Anna Armstrong

Speciation gradients and the distribution of biodiversity pp. 48-55

Dolph Schluter and Matthew W. Pennell

Beyond pairwise mechanisms of species coexistence in complex communities pp. 56-64

Jonathan M. Levine, Jordi Bascompte, Peter B. Adler and Stefano Allesina

Linking the influence and dependence of people on biodiversity across scales pp. 65-72

Forest Isbell, Andrew Gonzalez, Michel Loreau, Jane Cowles, Sandra Díaz, Andy Hector, Georgina M. Mace, David A. Wardle, Mary I. O'Connor, J. Emmett Duffy, Lindsay A. Turnbull, Patrick L. Thompson and Anne Larigauderie

Future threats to biodiversity and pathways to their prevention pp. 73-81

David Tilman, Michael Clark, David R. Williams, Kaitlin Kimmel, Stephen Polasky and Craig Packer

Coral reefs in the Anthropocene pp. 82-90

Terry P. Hughes, Michele L. Barnes, David R. Bellwood, Joshua E. Cinner, Graeme S. Cumming, Jeremy B. C. Jackson, Joanie Kleypas, Ingrid A. van de Leemput, Janice M. Lough, Tiffany H. Morrison, Stephen R. Palumbi, Egbert H. van Nes and Marten Scheffer

Upgrading protected areas to conserve wild biodiversity pp. 91-99

Robert M. Pringle

A neural circuit architecture for angular integration in Drosophila pp. 101-106

Jonathan Green, Atsuko Adachi, Kunal K. Shah, Jonathan D. Hirokawa, Pablo S. Magani and Gaby Maimon

Blocking FSH induces thermogenic adipose tissue and reduces body fat pp. 107-112

Peng Liu, Yaoting Ji, Tony Yuen, Elizabeth Rendina-Ruedy, Victoria E. DeMambro, Samarth Dhawan, Wahid Abu-Amer, Sudeh Izadmehr, Bin Zhou, Andrew C. Shin, Rauf Latif, Priyanthan Thangeswaran, Animesh Gupta, Jianhua Li, Valeria Shnayder, Samuel T. Robinson, Yue Eric Yu, Xingjian Zhang, Feiran Yang, Ping Lu, Yu Zhou, Ling-Ling Zhu, Douglas J. Oberlin, Terry F. Davies, Michaela R. Reagan, Aaron Brown, T. Rajendra Kumar, Solomon Epstein, Jameel Iqbal, Narayan G. Avadhani, Maria I. New, Henrik Molina, Jan B. van Klinken, Edward X. Guo, Christoph Buettner, Shozeb Haider, Zhuan Bian, Li Sun, Clifford J. Rosen and Mone Zaidi

Ensemble cryo-EM elucidates the mechanism of translation fidelity pp. 113-117

Anna B. Loveland, Gabriel Demo, Nikolaus Grigorieff and Andrei A. Korostelev

Phase-plate cryo-EM structure of a class B GPCR–G-protein complex pp. 118-123

Yi-Lynn Liang, Maryam Khoshouei, Mazdak Radjainia, Yan Zhang, Alisa Glukhova, Jeffrey Tarrasch, David M. Thal, Sebastian G. B. Furness, George Christopoulos, Thomas Coudrat, Radostin Danev, Wolfgang Baumeister, Laurence J. Miller, Arthur Christopoulos, Brian K. Kobilka, Denise Wootten, Georgios Skiniotis and Patrick M. Sexton

Electric-field control of tri-state phase transformation with a selective dual-ion switch pp. 124-128

Nianpeng Lu, Pengfei Zhang, Qinghua Zhang, Ruimin Qiao, Qing He, Hao-Bo Li, Yujia Wang, Jingwen Guo, Ding Zhang, Zheng Duan, Zhuolu Li, Meng Wang, Shuzhen Yang, Mingzhe Yan, Elke Arenholz, Shuyun Zhou, Wanli Yang, Lin Gu, Ce-Wen Nan, Jian Wu, Yoshinori Tokura and Pu Yu

Femtosecond response of polyatomic molecules to ultra-intense hard X-rays pp. 129-132

A. Rudenko, L. Inhester, K. Hanasaki, X. Li, S. J. Robatjazi, B. Erk, R. Boll, K. Toyota, Y. Hao, O. Vendrell, C. Bomme, E. Savelyev, B. Rudek, L. Foucar, S. H. Southworth, C. S. Lehmann, B. Kraessig, T. Marchenko, M. Simon, K. Ueda, K. R. Ferguson, M. Bucher, T. Gorkhover, S. Carron, R. Alonso-Mori, J. E. Koglin, J. Correa, G. J. Williams, S. Boutet, L. Young, C. Bostedt, S.-K. Son, R. Santra and D. Rolles

Isotopic evidence of multiple controls on atmospheric oxidants over climate transitions pp. 133-136

Lei Geng, Lee T. Murray, Loretta J. Mickley, Pu Lin, Qiang Fu, Andrew J. Schauer and Becky Alexander

Extreme hydrothermal conditions at an active plate-bounding fault pp. 137-140

Rupert Sutherland, John Townend, Virginia Toy, Phaedra Upton, Jamie Coussens, Michael Allen, Laura-May Baratin, Nicolas Barth, Leeza Becroft, Carolin Boese, Austin Boles, Carolyn Boulton, Neil G. R. Broderick, Lucie Janku-Capova, Brett M. Carpenter, Bernard Célérier, Calum Chamberlain, Alan Cooper, Ashley Coutts, Simon Cox, Lisa Craw, Mai-Linh Doan, Jennifer Eccles, Dan Faulkner, Jason Grieve, Julia Grochowski, Anton Gulley, Arthur Hartog, Jamie Howarth, Katrina Jacobs, Tamara Jeppson, Naoki Kato, Steven Keys, Martina Kirilova, Yusuke Kometani, Rob Langridge, Weiren Lin, Timothy Little, Adrienn Lukacs, Deirdre Mallyon, Elisabetta Mariani, Cécile Massiot, Loren Mathewson, Ben Melosh, Catriona Menzies, Jo Moore, Luiz Morales, Chance Morgan, Hiroshi Mori, Andre Niemeijer, Osamu Nishikawa, David Prior, Katrina Sauer, Martha Savage, Anja Schleicher, Douglas R. Schmitt, Norio Shigematsu, Sam Taylor-Offord, Damon Teagle, Harold Tobin, Robert Valdez, Konrad Weaver, Thomas Wiersberg, Jack Williams, Nick Woodman and Martin Zimmer

Large conservation gains possible for global biodiversity facets pp. 141-144

Laura J. Pollock, Wilfried Thuiller and Walter Jetz

Leaf bacterial diversity mediates plant diversity and ecosystem function relationships pp. 145-147

Isabelle Laforest-Lapointe, Alain Paquette, Christian Messier and Steven W. Kembel

The sunflower genome provides insights into oil metabolism, flowering and Asterid evolution pp. 148-152

Hélène Badouin, Jérôme Gouzy, Christopher J. Grassa, Florent Murat, S. Evan Staton, Ludovic Cottret, Christine Lelandais-Brière, Gregory L. Owens, Sébastien Carrère, Baptiste Mayjonade, Ludovic Legrand, Navdeep Gill, Nolan C. Kane, John E. Bowers, Sariel Hubner, Arnaud Bellec, Aurélie Bérard, Hélène Bergès, Nicolas Blanchet, Marie-Claude Boniface, Dominique Brunel, Olivier Catrice, Nadia Chaidir, Clotilde Claudel, Cécile Donnadieu, Thomas Faraut, Ghislain Fievet, Nicolas Helmstetter, Matthew King, Steven J. Knapp, Zhao Lai, Marie-Christine Le Paslier, Yannick Lippi, Lolita Lorenzon, Jennifer R. Mandel, Gwenola Marage, Gwenaëlle Marchand, Elodie Marquand, Emmanuelle Bret-Mestries, Evan Morien, Savithri Nambeesan, Thuy Nguyen, Prune Pegot-Espagnet, Nicolas Pouilly, Frances Raftis, Erika Sallet, Thomas Schiex, Justine Thomas, Céline Vandecasteele, Didier Varès, Felicity Vear, Sonia Vautrin, Martin Crespi, Brigitte Mangin, John M. Burke, Jérôme Salse, Stéphane Muños, Patrick Vincourt, Loren H. Rieseberg and Nicolas B. Langlade

Deletion of a mycobacterial divisome factor collapses single-cell phenotypic heterogeneity pp. 153-157

E. Hesper Rego, Rebecca E. Audette and Eric J. Rubin

Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells pp. 158-161

Alejandra Mendoza, Victoria Fang, Cynthia Chen, Madhavika Serasinghe, Akanksha Verma, James Muller, V. Sai Chaluvadi, Michael L. Dustin, Timothy Hla, Olivier Elemento, Jerry E. Chipuk and Susan R. Schwab

Applying systems-level spectral imaging and analysis to reveal the organelle interactome pp. 162-167

Alex M. Valm, Sarah Cohen, Wesley R. Legant, Justin Melunis, Uri Hershberg, Eric Wait, Andrew R. Cohen, Michael W. Davidson, Eric Betzig and Jennifer Lippincott-Schwartz

CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells pp. 168-172

Jiyeon Kim, Zeping Hu, Ling Cai, Kailong Li, Eunhee Choi, Brandon Faubert, Divya Bezwada, Jaime Rodriguez-Canales, Pamela Villalobos, Yu-Fen Lin, Min Ni, Kenneth E. Huffman, Luc Girard, Lauren A. Byers, Keziban Unsal-Kacmaz, Christopher G. Peña, John V. Heymach, Els Wauters, Johan Vansteenkiste, Diego H. Castrillon, Benjamin P. C. Chen, Ignacio Wistuba, Diether Lambrechts, Jian Xu, John D. Minna and Ralph J. DeBerardinis

Software simplified pp. 173-174

Andrew Silver

Workplace habits: Full-time is full enough pp. 175-177

Chris Woolston

Paths of glory pp. 177-177

Ushma S Neill

How to choose pp. 180-180

Michael Haynes