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2021, volume 598, articles 7882

Author Correction: A molecular single-cell lung atlas of lethal COVID-19 pp. E2-E2

Johannes C. Melms, Jana Biermann, Huachao Huang, Yiping Wang, Ajay Nair, Somnath Tagore, Igor Katsyv, André F. Rendeiro, Amit Dipak Amin, Denis Schapiro, Chris J. Frangieh, Adrienne M. Luoma, Aveline Filliol, Yinshan Fang, Hiranmayi Ravichandran, Mariano G. Clausi, George A. Alba, Meri Rogava, Sean W. Chen, Patricia Ho, Daniel T. Montoro, Adam E. Kornberg, Arnold S. Han, Mathieu F. Bakhoum, Niroshana Anandasabapathy, Mayte Suárez-Fariñas, Samuel F. Bakhoum, Yaron Bram, Alain Borczuk, Xinzheng V. Guo, Jay H. Lefkowitch, Charles Marboe, Stephen M. Lagana, Armando Portillo, Emily J. Tsai, Emmanuel Zorn, Glen S. Markowitz, Robert F. Schwabe, Robert E. Schwartz, Olivier Elemento, Anjali Saqi, Hanina Hibshoosh, Jianwen Que and Benjamin Izar

Author Correction: Structural basis of ketamine action on human NMDA receptors pp. E3-E3

Youyi Zhang, Fei Ye, Tongtong Zhang, Shiyun Lv, Liping Zhou, Daohai Du, He Lin, Fei Guo, Cheng Luo and Shujia Zhu

Publisher Correction: Dysregulation of brain and choroid plexus cell types in severe COVID-19 pp. E4-E4

Andrew C. Yang, Fabian Kern, Patricia M. Losada, Maayan R. Agam, Christina A. Maat, Georges P. Schmartz, Tobias Fehlmann, Julian A. Stein, Nicholas Schaum, Davis P. Lee, Kruti Calcuttawala, Ryan T. Vest, Daniela Berdnik, Nannan Lu, Oliver Hahn, David Gate, M. Windy McNerney, Divya Channappa, Inma Cobos, Nicole Ludwig, Walter J. Schulz-Schaeffer, Andreas Keller and Tony Wyss-Coray

Publisher Correction: Demonstration of reduced neoclassical energy transport in Wendelstein 7-X pp. E5-E5

C. D. Beidler, H. M. Smith, A. Alonso, T. Andreeva, J. Baldzuhn, M. N. A. Beurskens, M. Borchardt, S. A. Bozhenkov, K. J. Brunner, H. Damm, M. Drevlak, O. P. Ford, G. Fuchert, J. Geiger, P. Helander, U. Hergenhahn, M. Hirsch, U. Höfel, Ye. O. Kazakov, R. Kleiber, M. Krychowiak, S. Kwak, A. Langenberg, H. P. Laqua, U. Neuner, N. A. Pablant, E. Pasch, A. Pavone, T. S. Pedersen, K. Rahbarnia, J. Schilling, E. R. Scott, T. Stange, J. Svensson, H. Thomsen, Y. Turkin, F. Warmer, R. C. Wolf and Dengjun Zhang

The high burden of infectious disease pp. S9-S9

Catherine Armitage

Uneven attention hampers the drive to control infectious diseases pp. S10-S13

Sarah DeWeerdt

Overlooked and underfunded: neglected diseases exert a toll pp. S20-S22

Michael Eisenstein

An mRNA vaccine industry in the making pp. S30-S31

Neil Savage

Wolbachia goes to work in the war on mosquitoes pp. S32-S34

Sandy Ong

This digital-hygiene routine will protect your scholarship pp. 541-541

Guillaume Cabanac

Attempt to charge Mexican scientists with ‘organized crime’ prompts international outcry pp. 547-548

Sara Reardon

Physicists make most precise measurement ever of neutron’s lifetime pp. 549-549

Davide Castelvecchi

Ancient DNA points to origins of modern domestic horses pp. 550-550

Tosin Thompson

Climate change: Nature readers say their fears are growing pp. 551-551

Quirin Schiermeier

COVID vaccine makers brace for a variant worse than Delta pp. 552-553

Emily Waltz

‘Politicians shouldn’t meddle’: new chief of Europe’s major research funder shares priorities pp. 553-553

Quirin Schiermeier

The shifting sands of ‘gain-of-function’ research pp. 554-557

Amber Dance

The secret lives of cells — as never seen before pp. 558-560

Diana Kwon

Inside the lawsuit that ended US gene patenting pp. 561-562

Heidi Ledford

Climate lessons from COVID, and the end of paperwork: Books in brief pp. 562-562

Andrew Robinson

Predatory publishers’ latest scam: bootlegged and rebranded papers pp. 563-565

Kyle Siler, Philippe Vincent-Lamarre, Cassidy R. Sugimoto and Vincent Larivière

COP26: set a minimum global carbon price for emissions pp. 566-566

Stefano Carattini

Brazil’s scientists face 90% budget cut pp. 566-566

Alicia J. Kowaltowski

Air quality: WHO guidelines could deepen inequities pp. 566-566

Forrest Lacey, Rajesh Kumar, Gabriele Pfister, Jean-Francois Lamarque, Cassandra O’Lenick and Guy Brasseur

Thousands of new and improved mineral symbols pp. 566-566

Laurence N. Warr

Machine learning enables global solar-panel detection pp. 567-568

Lynn H. Kaack

Opioid peptide signal in the brain makes mice hungrier for reward pp. 568-570

Lola Welsch and Brigitte L. Kieffer

Bacteria recycle tumour waste to fuel immune cells pp. 570-571

Laurence C. Chen and Yvonne Y. Chen

A compact device sustains a fluid of bosons pp. 571-572

Denis Golež and Zhiyuan Sun

Electroacupuncture activates neurons to switch off inflammation pp. 573-574

Luis Ulloa

Call for a framework for reporting evidence for life beyond Earth pp. 575-579

James Green, Tori Hoehler, Marc Neveu, Shawn Domagal-Goldman, Daniella Scalice and Mary Voytek

A solar C/O and sub-solar metallicity in a hot Jupiter atmosphere pp. 580-584

Michael R. Line, Matteo Brogi, Jacob L. Bean, Siddharth Gandhi, Joseph Zalesky, Vivien Parmentier, Peter Smith, Gregory N. Mace, Megan Mansfield, Eliza M.-R. Kempton, Jonathan J. Fortney, Evgenya Shkolnik, Jennifer Patience, Emily Rauscher, Jean-Michel Désert and Joost P. Wardenier

Strongly correlated excitonic insulator in atomic double layers pp. 585-589

Liguo Ma, Phuong X. Nguyen, Zefang Wang, Yongxin Zeng, Kenji Watanabe, Takashi Taniguchi, Allan H. MacDonald, Kin Fai Mak and Jie Shan

Copper-coordinated cellulose ion conductors for solid-state batteries pp. 590-596

Chunpeng Yang, Qisheng Wu, Weiqi Xie, Xin Zhang, Alexandra Brozena, Jin Zheng, Mounesha N. Garaga, Byung Hee Ko, Yimin Mao, Shuaiming He, Yue Gao, Pengbo Wang, Madhusudan Tyagi, Feng Jiao, Robert Briber, Paul Albertus, Chunsheng Wang, Steven Greenbaum, Yan-Yan Hu, Akira Isogai, Martin Winter, Kang Xu, Yue Qi and Liangbing Hu

Multicomponent alkene azidoarylation by anion-mediated dual catalysis pp. 597-603

Ala Bunescu, Yusra Abdelhamid and Matthew J. Gaunt

A global inventory of photovoltaic solar energy generating units pp. 604-610

L. Kruitwagen, K. T. Story, J. Friedrich, L. Byers, S. Skillman and C. Hepburn

Global potential for harvesting drinking water from air using solar energy pp. 611-617

Jackson Lord, Ashley Thomas, Neil Treat, Matthew Forkin, Robert Bain, Pierre Dulac, Cyrus H. Behroozi, Tilek Mamutov, Jillia Fongheiser, Nicole Kobilansky, Shane Washburn, Claudia Truesdell, Clare Lee and Philipp H. Schmaelzle

Indo-Pacific Walker circulation drove Pleistocene African aridification pp. 618-623

H. J. L. Lubbe, I. R. Hall, S. Barker, S. R. Hemming, T. F. Baars, A. Starr, J. Just, B. C. Backeberg and J. C. A. Joordens

Spatiotemporal origin of soil water taken up by vegetation pp. 624-628

Gonzalo Miguez-Macho and Ying Fan

Dairying enabled Early Bronze Age Yamnaya steppe expansions pp. 629-633

Shevan Wilkin, Alicia Ventresca Miller, Ricardo Fernandes, Robert Spengler, William T.-T. Taylor, Dorcas R. Brown, David Reich, Douglas J. Kennett, Brendan J. Culleton, Laura Kunz, Claudia Fortes, Aleksandra Kitova, Pavel Kuznetsov, Andrey Epimakhov, Victor F. Zaibert, Alan K. Outram, Egor Kitov, Aleksandr Khokhlov, David Anthony and Nicole Boivin

The origins and spread of domestic horses from the Western Eurasian steppes pp. 634-640

Pablo Librado, Naveed Khan, Antoine Fages, Mariya A. Kusliy, Tomasz Suchan, Laure Tonasso-Calvière, Stéphanie Schiavinato, Duha Alioglu, Aurore Fromentier, Aude Perdereau, Jean-Marc Aury, Charleen Gaunitz, Lorelei Chauvey, Andaine Seguin-Orlando, Clio Der Sarkissian, John Southon, Beth Shapiro, Alexey A. Tishkin, Alexey A. Kovalev, Saleh Alquraishi, Ahmed H. Alfarhan, Khaled A. S. Al-Rasheid, Timo Seregély, Lutz Klassen, Rune Iversen, Olivier Bignon-Lau, Pierre Bodu, Monique Olive, Jean-Christophe Castel, Myriam Boudadi-Maligne, Nadir Alvarez, Mietje Germonpré, Magdalena Moskal-del Hoyo, Jarosław Wilczyński, Sylwia Pospuła, Anna Lasota-Kuś, Krzysztof Tunia, Marek Nowak, Eve Rannamäe, Urmas Saarma, Gennady Boeskorov, Lembi Lōugas, René Kyselý, Lubomír Peške, Adrian Bălășescu, Valentin Dumitrașcu, Roxana Dobrescu, Daniel Gerber, Viktória Kiss, Anna Szécsényi-Nagy, Balázs G. Mende, Zsolt Gallina, Krisztina Somogyi, Gabriella Kulcsár, Erika Gál, Robin Bendrey, Morten E. Allentoft, Ghenadie Sirbu, Valentin Dergachev, Henry Shephard, Noémie Tomadini, Sandrine Grouard, Aleksei Kasparov, Alexander E. Basilyan, Mikhail A. Anisimov, Pavel A. Nikolskiy, Elena Y. Pavlova, Vladimir Pitulko, Gottfried Brem, Barbara Wallner, Christoph Schwall, Marcel Keller, Keiko Kitagawa, Alexander N. Bessudnov, Alexander Bessudnov, William Taylor, Jérome Magail, Jamiyan-Ombo Gantulga, Jamsranjav Bayarsaikhan, Diimaajav Erdenebaatar, Kubatbeek Tabaldiev, Enkhbayar Mijiddorj, Bazartseren Boldgiv, Turbat Tsagaan, Mélanie Pruvost, Sandra Olsen, Cheryl A. Makarewicz, Silvia Valenzuela Lamas, Silvia Albizuri Canadell, Ariadna Nieto Espinet, Ma Pilar Iborra, Jaime Lira Garrido, Esther Rodríguez González, Sebastián Celestino, Carmen Olària, Juan Luis Arsuaga, Nadiia Kotova, Alexander Pryor, Pam Crabtree, Rinat Zhumatayev, Abdesh Toleubaev, Nina L. Morgunova, Tatiana Kuznetsova, David Lordkipanize, Matilde Marzullo, Ornella Prato, Giovanna Bagnasco Gianni, Umberto Tecchiati, Benoit Clavel, Sébastien Lepetz, Hossein Davoudi, Marjan Mashkour, Natalia Ya. Berezina, Philipp W. Stockhammer, Johannes Krause, Wolfgang Haak, Arturo Morales-Muñiz, Norbert Benecke, Michael Hofreiter, Arne Ludwig, Alexander S. Graphodatsky, Joris Peters, Kirill Yu. Kiryushin, Tumur-Ochir Iderkhangai, Nikolay A. Bokovenko, Sergey K. Vasiliev, Nikolai N. Seregin, Konstantin V. Chugunov, Natalya A. Plasteeva, Gennady F. Baryshnikov, Ekaterina Petrova, Mikhail Sablin, Elina Ananyevskaya, Andrey Logvin, Irina Shevnina, Victor Logvin, Saule Kalieva, Valeriy Loman, Igor Kukushkin, Ilya Merz, Victor Merz, Sergazy Sakenov, Victor Varfolomeyev, Emma Usmanova, Viktor Zaibert, Benjamin Arbuckle, Andrey B. Belinskiy, Alexej Kalmykov, Sabine Reinhold, Svend Hansen, Aleksandr I. Yudin, Alekandr A. Vybornov, Andrey Epimakhov, Natalia S. Berezina, Natalia Roslyakova, Pavel A. Kosintsev, Pavel F. Kuznetsov, David Anthony, Guus J. Kroonen, Kristian Kristiansen, Patrick Wincker, Alan Outram and Ludovic Orlando

A neuroanatomical basis for electroacupuncture to drive the vagal–adrenal axis pp. 641-645

Shenbin Liu, Zhifu Wang, Yangshuai Su, Lu Qi, Wei Yang, Mingzhou Fu, Xianghong Jing, Yanqing Wang and Qiufu Ma

An endogenous opioid circuit determines state-dependent reward consumption pp. 646-651

Daniel C. Castro, Corinna S. Oswell, Eric T. Zhang, Christian E. Pedersen, Sean C. Piantadosi, Mark A. Rossi, Avery C. Hunker, Anthony Guglin, Jose A. Morón, Larry S. Zweifel, Garret D. Stuber and Michael R. Bruchas

Leprosy in wild chimpanzees pp. 652-656

Kimberley J. Hockings, Benjamin Mubemba, Charlotte Avanzi, Kamilla Pleh, Ariane Düx, Elena Bersacola, Joana Bessa, Marina Ramon, Sonja Metzger, Livia V. Patrono, Jenny E. Jaffe, Andrej Benjak, Camille Bonneaud, Philippe Busso, Emmanuel Couacy-Hymann, Moussa Gado, Sebastien Gagneux, Roch C. Johnson, Mamoudou Kodio, Joshua Lynton-Jenkins, Irina Morozova, Kerstin Mätz-Rensing, Aissa Regalla, Abílio R. Said, Verena J. Schuenemann, Samba O. Sow, John S. Spencer, Markus Ulrich, Hyacinthe Zoubi, Stewart T. Cole, Roman M. Wittig, Sebastien Calvignac-Spencer and Fabian H. Leendertz

Parallelism of intestinal secretory IgA shapes functional microbial fitness pp. 657-661

Tim Rollenske, Sophie Burkhalter, Lukas Muerner, Stephan Gunten, Jolanta Lukasiewicz, Hedda Wardemann and Andrew J. Macpherson

Metabolic modulation of tumours with engineered bacteria for immunotherapy pp. 662-666

Fernando P. Canale, Camilla Basso, Gaia Antonini, Michela Perotti, Ning Li, Anna Sokolovska, Julia Neumann, Michael J. James, Stefania Geiger, Wenjie Jin, Jean-Philippe Theurillat, Kip A. West, Daniel S. Leventhal, Jose M. Lora, Federica Sallusto and Roger Geiger

The cellular environment shapes the nuclear pore complex architecture pp. 667-671

Anthony P. Schuller, Matthias Wojtynek, David Mankus, Meltem Tatli, Rafael Kronenberg-Tenga, Saroj G. Regmi, Phat V. Dip, Abigail K. R. Lytton-Jean, Edward J. Brignole, Mary Dasso, Karsten Weis, Ohad Medalia and Thomas U. Schwartz

Structure of Venezuelan equine encephalitis virus in complex with the LDLRAD3 receptor pp. 672-676

Katherine Basore, Hongming Ma, Natasha M. Kafai, Samantha Mackin, Arthur S. Kim, Christopher A. Nelson, Michael S. Diamond and Daved H. Fremont

Structure of Venezuelan equine encephalitis virus with its receptor LDLRAD3 pp. 677-681

Bingting Ma, Cuiqing Huang, Jun Ma, Ye Xiang and Xinzheng Zhang

KDM5B promotes immune evasion by recruiting SETDB1 to silence retroelements pp. 682-687

Shang-Min Zhang, Wesley L. Cai, Xiaoni Liu, Durga Thakral, Jiesi Luo, Lok Hei Chan, Meaghan K. McGeary, Eric Song, Kim R. M. Blenman, Goran Micevic, Shlomit Jessel, Yangyi Zhang, Mingzhu Yin, Carmen J. Booth, Lucia B. Jilaveanu, William Damsky, Mario Sznol, Harriet M. Kluger, Akiko Iwasaki, Marcus W. Bosenberg and Qin Yan

Structures of full-length glycoprotein hormone receptor signalling complexes pp. 688-692

Jia Duan, Peiyu Xu, Xi Cheng, Chunyou Mao, Tristan Croll, Xinheng He, Jingjing Shi, Xiaodong Luan, Wanchao Yin, Erli You, Qiufeng Liu, Shuyang Zhang, Hualiang Jiang, Yan Zhang, Yi Jiang and H. Eric Xu

Academia’s ableist mindset needs to change pp. 693-695

Kendall Powell

Surmounting challenges with a passion for science pp. 698-698

Chris Woolston

2021, volume 598, articles 7881

Author Correction: Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers pp. E1-E1

Justina X. Caushi, Jiajia Zhang, Zhicheng Ji, Ajay Vaghasia, Boyang Zhang, Emily Han-Chung Hsiue, Brian J. Mog, Wenpin Hou, Sune Justesen, Richard Blosser, Ada Tam, Valsamo Anagnostou, Tricia R. Cottrell, Haidan Guo, Hok Yee Chan, Dipika Singh, Sampriti Thapa, Arbor G. Dykema, Poromendro Burman, Begum Choudhury, Luis Aparicio, Laurene S. Cheung, Mara Lanis, Zineb Belcaid, Margueritta El Asmar, Peter B. Illei, Rulin Wang, Jennifer Meyers, Kornel Schuebel, Anuj Gupta, Alyza Skaist, Sarah Wheelan, Jarushka Naidoo, Kristen A. Marrone, Malcolm Brock, Jinny Ha, Errol L. Bush, Bernard J. Park, Matthew Bott, David R. Jones, Joshua E. Reuss, Victor E. Velculescu, Jamie E. Chaft, Kenneth W. Kinzler, Shibin Zhou, Bert Vogelstein, Janis M. Taube, Matthew D. Hellmann, Julie R. Brahmer, Taha Merghoub, Patrick M. Forde, Srinivasan Yegnasubramanian, Hongkai Ji, Drew M. Pardoll and Kellie N. Smith

Before making a mammoth, ask the public pp. 387-387

Victoria Herridge

COVID super-immunity: one of the pandemic’s great puzzles pp. 393-394

Ewen Callaway

Why easing COVID restrictions could prompt a fierce flu rebound pp. 395-395

Nicola Jones

Chilean researchers unhappy following investigation of star neuroscientist pp. 396-397

Emiliano Rodríguez Mega

Burnt seeds show people used tobacco 12,000 years ago pp. 397-398

Tosin Thompson

China’s COVID vaccines have been crucial — now immunity is waning pp. 398-399

Smriti Mallapaty

The broken $100-billion promise of climate finance — and how to fix it pp. 400-402

Jocelyn Timperley

Why fossil fuel subsidies are so hard to kill pp. 403-405

Jocelyn Timperley

How cigarettes became a civil-rights issue pp. 407-408

Nidhi Subbaraman

Synthetic biology — a call to meddle better pp. 408-409

Gaia Vince

Transformative hydrogen and wrestling with testosterone: Books in brief pp. 409-409

Andrew Robinson

Congo Basin rainforest — invest US$150 million in science pp. 411-414

Lee J. T. White, Eve Bazaiba Masudi, Jules Doret Ndongo, Rosalie Matondo, Arlette Soudan-Nonault, Alfred Ngomanda, Ifo Suspense Averti, Corneille E. N. Ewango, Bonaventure Sonké and Simon L. Lewis

Countries of the Indo-Gangetic Plain must unite against air pollution pp. 415-415

Muhammad Fahim Khokhar, Muhammad Shehzaib Anjum, Abdus Salam, Vinayak Sinha, Manish Naja, Hiroshi Tanimoto, James H. Crawford and Mohammed Iqbal Mead

United States has several programmes for early-career leaders pp. 415-415

Dalal Najib, John Boright and John Hildebrand

Credit local authors fairly on international research papers pp. 415-415

Angela I. N. Obasi, Seye Abimbola, Ndekya Oriyo, Ben Morton, André Vercueil and Refiloe Masekela

The lesson of talk over tea and cakes? Local research matters pp. 415-415

Sandersan Onie and Ashra Daswin

The genetic symphony underlying evolution of the brain’s prefrontal cortex pp. 417-418

Jenelle L. Wallace and Alex A. Pollen

Untwisted trilayer graphene hosts superconductivity and magnetism pp. 418-420

Thiti Taychatanapat

A step towards therapeutics for dengue pp. 420-421

Scott B. Biering and Eva Harris

Non-magnetic objects induced to move by electromagnets pp. 421-423

Eric Diller

Flies sense the world while sleeping pp. 423-424

Wanhe Li and Alex C. Keene

Carbon monoxide gas produced by a giant impact in the inner region of a young system pp. 425-428

Tajana Schneiderman, Luca Matrà, Alan P. Jackson, Grant M. Kennedy, Quentin Kral, Sebastián Marino, Karin I. Öberg, Kate Y. L. Su, David J. Wilner and Mark C. Wyatt

Half- and quarter-metals in rhombohedral trilayer graphene pp. 429-433

Haoxin Zhou, Tian Xie, Areg Ghazaryan, Tobias Holder, James R. Ehrets, Eric M. Spanton, Takashi Taniguchi, Kenji Watanabe, Erez Berg, Maksym Serbyn and Andrea F. Young

Superconductivity in rhombohedral trilayer graphene pp. 434-438

Haoxin Zhou, Tian Xie, Takashi Taniguchi, Kenji Watanabe and Andrea F. Young

Dexterous magnetic manipulation of conductive non-magnetic objects pp. 439-443

Lan N. Pham, Griffin F. Tabor, Ashkan Pourkand, Jacob L. B. Aman, Tucker Hermans and Jake J. Abbott

Perovskite solar cells with atomically coherent interlayers on SnO2 electrodes pp. 444-450

Hanul Min, Do Yoon Lee, Junu Kim, Gwisu Kim, Kyoung Su Lee, Jongbeom Kim, Min Jae Paik, Young Ki Kim, Kwang S. Kim, Min Gyu Kim, Tae Joo Shin and Sang Seok

Metallaphotoredox-enabled deoxygenative arylation of alcohols pp. 451-456

Zhe Dong and David W. C. MacMillan

Pliocene decoupling of equatorial Pacific temperature and pH gradients pp. 457-461

Madison G. Shankle, Natalie J. Burls, Alexey V. Fedorov, Matthew D. Thomas, Wei Liu, Donald E. Penman, Heather L. Ford, Peter H. Jacobs, Noah J. Planavsky and Pincelli M. Hull

Direct radiative effects of airborne microplastics pp. 462-467

Laura E. Revell, Peter Kuma, Eric C. Ru, Walter R. C. Somerville and Sally Gaw

The three major axes of terrestrial ecosystem function pp. 468-472

Mirco Migliavacca, Talie Musavi, Miguel D. Mahecha, Jacob A. Nelson, Jürgen Knauer, Dennis D. Baldocchi, Oscar Perez-Priego, Rune Christiansen, Jonas Peters, Karen Anderson, Michael Bahn, T. Andrew Black, Peter D. Blanken, Damien Bonal, Nina Buchmann, Silvia Caldararu, Arnaud Carrara, Nuno Carvalhais, Alessandro Cescatti, Jiquan Chen, Jamie Cleverly, Edoardo Cremonese, Ankur R. Desai, Tarek S. El-Madany, Martha M. Farella, Marcos Fernández-Martínez, Gianluca Filippa, Matthias Forkel, Marta Galvagno, Ulisse Gomarasca, Christopher M. Gough, Mathias Göckede, Andreas Ibrom, Hiroki Ikawa, Ivan A. Janssens, Martin Jung, Jens Kattge, Trevor F. Keenan, Alexander Knohl, Hideki Kobayashi, Guido Kraemer, Beverly E. Law, Michael J. Liddell, Xuanlong Ma, Ivan Mammarella, David Martini, Craig Macfarlane, Giorgio Matteucci, Leonardo Montagnani, Daniel E. Pabon-Moreno, Cinzia Panigada, Dario Papale, Elise Pendall, Josep Penuelas, Richard P. Phillips, Peter B. Reich, Micol Rossini, Eyal Rotenberg, Russell L. Scott, Clement Stahl, Ulrich Weber, Georg Wohlfahrt, Sebastian Wolf, Ian J. Wright, Dan Yakir, Sönke Zaehle and Markus Reichstein

Convergent somatic mutations in metabolism genes in chronic liver disease pp. 473-478

Stanley W. K. Ng, Foad J. Rouhani, Simon F. Brunner, Natalia Brzozowska, Sarah J. Aitken, Ming Yang, Federico Abascal, Luiza Moore, Efterpi Nikitopoulou, Lia Chappell, Daniel Leongamornlert, Aleksandra Ivovic, Philip Robinson, Timothy Butler, Mathijs A. Sanders, Nicholas Williams, Tim H. H. Coorens, Jon Teague, Keiran Raine, Adam P. Butler, Yvette Hooks, Beverley Wilson, Natalie Birtchnell, Huw Naylor, Susan E. Davies, Michael R. Stratton, Iñigo Martincorena, Raheleh Rahbari, Christian Frezza, Matthew Hoare and Peter J. Campbell

Sensory processing during sleep in Drosophila melanogaster pp. 479-482

Alice S. French, Quentin Geissmann, Esteban J. Beckwith and Giorgio F. Gilestro

Regulation of prefrontal patterning and connectivity by retinoic acid pp. 483-488

Mikihito Shibata, Kartik Pattabiraman, Belen Lorente-Galdos, David Andrijevic, Suel-Kee Kim, Navjot Kaur, Sydney K. Muchnik, Xiaojun Xing, Gabriel Santpere, Andre M. M. Sousa and Nenad Sestan

Hominini-specific regulation of CBLN2 increases prefrontal spinogenesis pp. 489-494

Mikihito Shibata, Kartik Pattabiraman, Sydney K. Muchnik, Navjot Kaur, Yury M. Morozov, Xiaoyang Cheng, Stephen G. Waxman and Nenad Sestan

The EDS1–PAD4–ADR1 node mediates Arabidopsis pattern-triggered immunity pp. 495-499

Rory N. Pruitt, Federica Locci, Friederike Wanke, Lisha Zhang, Svenja C. Saile, Anna Joe, Darya Karelina, Chenlei Hua, Katja Fröhlich, Wei-Lin Wan, Meijuan Hu, Shaofei Rao, Sara C. Stolze, Anne Harzen, Andrea A. Gust, Klaus Harter, Matthieu H. A. J. Joosten, Bart P. H. J. Thomma, Jian-Min Zhou, Jeffery L. Dangl, Detlef Weigel, Hirofumi Nakagami, Claudia Oecking, Farid El Kasmi, Jane E. Parker and Thorsten Nürnberger

Activation of TIR signalling boosts pattern-triggered immunity pp. 500-503

Hainan Tian, Zhongshou Wu, Siyu Chen, Kevin Ao, Weijie Huang, Hoda Yaghmaiean, Tongjun Sun, Fang Xu, Yanjun Zhang, Shucai Wang, Xin Li and Yuelin Zhang

A pan-serotype dengue virus inhibitor targeting the NS3–NS4B interaction pp. 504-509

Suzanne J. F. Kaptein, Olivia Goethals, Dominik Kiemel, Arnaud Marchand, Bart Kesteleyn, Jean-François Bonfanti, Dorothée Bardiot, Bart Stoops, Tim H. M. Jonckers, Kai Dallmeier, Peggy Geluykens, Kim Thys, Marjolein Crabbe, Laurent Chatel-Chaix, Max Münster, Gilles Querat, Franck Touret, Xavier Lamballerie, Pierre Raboisson, Kenny Simmen, Patrick Chaltin, Ralf Bartenschlager, Marnix Loock and Johan Neyts

Mutant clones in normal epithelium outcompete and eliminate emerging tumours pp. 510-514

B. Colom, A. Herms, M. W. J. Hall, S. C. Dentro, C. King, R. K. Sood, M. P. Alcolea, G. Piedrafita, D. Fernandez-Antoran, S. H. Ong, J. C. Fowler, K. T. Mahbubani, K. Saeb-Parsy, M. Gerstung, B. A. Hall and P. H. Jones

Mechanism for Cas4-assisted directional spacer acquisition in CRISPR–Cas pp. 515-520

Chunyi Hu, Cristóbal Almendros, Ki Hyun Nam, Ana Rita Costa, Jochem N. A. Vink, Anna C. Haagsma, Saket R. Bagde, Stan J. J. Brouns and Ailong Ke

Structural insights into hepatitis C virus receptor binding and entry pp. 521-525

Ashish Kumar, Reafa A. Hossain, Samantha A. Yost, Wei Bu, Yuanyuan Wang, Altaira D. Dearborn, Arash Grakoui, Jeffrey I. Cohen and Joseph Marcotrigiano

How three refugee scientists kept their research hopes alive pp. 527-529

Virginia Gewin

Saving hawksbill sea turtles from rats, cats and Hurricane Ida pp. 532-532

Natasha Gilbert

2021, volume 598, articles 7880

How AI is helping the natural sciences pp. S5-S7

Jack Leeming

COVID lesson: trust the public with hard truths pp. 237-237

Michael Bang Petersen

Science agency on trial following deadly White Island volcano eruption pp. 243-244

Dyani Lewis

Head of Wellcome-funded Malawi health project investigated for bullying pp. 245-245

Linda Nordling

Climate modellers and theorist of complex systems share physics Nobel pp. 246-247

Davide Castelvecchi and Nisha Gaind

Medicine Nobel goes to scientists who discovered biology of senses pp. 246-246

Heidi Ledford and Ewen Callaway

‘Elegant’ catalysts that tell left from right scoop chemistry Nobel pp. 247-248

Davide Castelvecchi and Emma Stoye

Why COVID vaccines didn’t win a science Nobel this year pp. 248-248

Ewen Callaway

NASA won’t rename James Webb telescope — and astronomers are angry pp. 249-249

Alexandra Witze

‘I hope you die’: how the COVID pandemic unleashed attacks on scientists pp. 250-253

Bianca Nogrady

Make electric vehicles lighter to maximize climate and safety benefits pp. 254-256

Blake Shaffer, Maximilian Auffhammer and Constantine Samaras

Recognize 727 UNESCO Biosphere Reserves for biodiversity COP15 pp. 257-257

Alicia D. Barraclough, Maureen G. Reed, Inger Elisabeth Måren, Martin F. Price, Andrés Moreira-Muñoz and Kaera Coetzer

Why no mention of overpopulation in talk of food systems? pp. 257-257

Paul R. Ehrlich

Keep online option at conferences — it makes them more inclusive pp. 257-257

Rocío Joo

Anthropocene event idea is empowering pp. 257-257

Jan Kunnas

Venus might never have been habitable pp. 259-260

James F. Kasting and Chester E. Harman

A spotlight on seafood for global human nutrition pp. 260-262

Lotte Lauritzen

The cost of changes in energy use in a warming world pp. 262-263

Katrina Jessoe and Frances C. Moore

Structural strains of misfolded tau protein define different diseases pp. 264-265

Henning Stahlberg and Roland Riek

Evidence that overnight fasting could extend healthy lifespan pp. 265-266

Stephen L. Helfand and Rafael de Cabo

A bimodal burst energy distribution of a repeating fast radio burst source pp. 267-271

D. Li, P. Wang, W. W. Zhu, B. Zhang, X. X. Zhang, R. Duan, Y. K. Zhang, Y. Feng, N. Y. Tang, S. Chatterjee, J. M. Cordes, M. Cruces, S. Dai, V. Gajjar, G. Hobbs, C. Jin, M. Kramer, D. R. Lorimer, C. C. Miao, C. H. Niu, J. R. Niu, Z. C. Pan, L. Qian, L. Spitler, D. Werthimer, G. Q. Zhang, F. Y. Wang, X. Y. Xie, Y. L. Yue, L. Zhang, Q. J. Zhi and Y. Zhu

A Jovian analogue orbiting a white dwarf star pp. 272-275

J. W. Blackman, J. P. Beaulieu, D. P. Bennett, C. Danielski, C. Alard, A. A. Cole, A. Vandorou, C. Ranc, S. K. Terry, A. Bhattacharya, I. Bond, E. Bachelet, D. Veras, N. Koshimoto, V. Batista and J. B. Marquette

Day–night cloud asymmetry prevents early oceans on Venus but not on Earth pp. 276-280

Martin Turbet, Emeline Bolmont, Guillaume Chaverot, David Ehrenreich, Jérémy Leconte and Emmanuel Marcq

Fault-tolerant control of an error-corrected qubit pp. 281-286

Laird Egan, Dripto M. Debroy, Crystal Noel, Andrew Risinger, Daiwei Zhu, Debopriyo Biswas, Michael Newman, Muyuan Li, Kenneth R. Brown, Marko Cetina and Christopher Monroe

Observation of fractional edge excitations in nanographene spin chains pp. 287-292

Shantanu Mishra, Gonçalo Catarina, Fupeng Wu, Ricardo Ortiz, David Jacob, Kristjan Eimre, Ji Ma, Carlo A. Pignedoli, Xinliang Feng, Pascal Ruffieux, Joaquín Fernández-Rossier and Roman Fasel

Superior robustness of anomalous non-reciprocal topological edge states pp. 293-297

Zhe Zhang, Pierre Delplace and Romain Fleury

An elastic metal–organic crystal with a densely catenated backbone pp. 298-303

Wenjing Meng, Shun Kondo, Takuji Ito, Kazuki Komatsu, Jenny Pirillo, Yuh Hijikata, Yuichi Ikuhara, Takuzo Aida and Hiroshi Sato

Photocatalytic solar hydrogen production from water on a 100-m2 scale pp. 304-307

Hiroshi Nishiyama, Taro Yamada, Mamiko Nakabayashi, Yoshiki Maehara, Masaharu Yamaguchi, Yasuko Kuromiya, Yoshie Nagatsuma, Hiromasa Tokudome, Seiji Akiyama, Tomoaki Watanabe, Ryoichi Narushima, Sayuri Okunaka, Naoya Shibata, Tsuyoshi Takata, Takashi Hisatomi and Kazunari Domen

Estimating a social cost of carbon for global energy consumption pp. 308-314

Ashwin Rode, Tamma Carleton, Michael Delgado, Michael Greenstone, Trevor Houser, Solomon Hsiang, Andrew Hultgren, Amir Jina, Robert Kopp, Kelly E. McCusker, Ishan Nath, James Rising and Jiacan Yuan

Aquatic foods to nourish nations pp. 315-320

Christopher D. Golden, J. Zachary Koehn, Alon Shepon, Simone Passarelli, Christopher M. Free, Daniel F. Viana, Holger Matthey, Jacob G. Eurich, Jessica A. Gephart, Etienne Fluet-Chouinard, Elizabeth A. Nyboer, Abigail J. Lynch, Marian Kjellevold, Sabri Bromage, Pierre Charlebois, Manuel Barange, Stefania Vannuccini, Ling Cao, Kristin M. Kleisner, Eric B. Rimm, Goodarz Danaei, Camille DeSisto, Heather Kelahan, Kathryn J. Fiorella, David C. Little, Edward H. Allison, Jessica Fanzo and Shakuntala H. Thilsted

Dopamine facilitates associative memory encoding in the entorhinal cortex pp. 321-326

Jason Y. Lee, Heechul Jun, Shogo Soma, Tomoaki Nakazono, Kaori Shiraiwa, Ananya Dasgupta, Tatsuki Nakagawa, Jiayun L. Xie, Jasmine Chavez, Rodrigo Romo, Sandra Yungblut, Meiko Hagihara, Koshi Murata and Kei M. Igarashi

Blood and immune development in human fetal bone marrow and Down syndrome pp. 327-331

Laura Jardine, Simone Webb, Issac Goh, Mariana Quiroga Londoño, Gary Reynolds, Michael Mather, Bayanne Olabi, Emily Stephenson, Rachel A. Botting, Dave Horsfall, Justin Engelbert, Daniel Maunder, Nicole Mende, Caitlin Murnane, Emma Dann, Jim McGrath, Hamish King, Iwo Kucinski, Rachel Queen, Christopher D. Carey, Caroline Shrubsole, Elizabeth Poyner, Meghan Acres, Claire Jones, Thomas Ness, Rowen Coulthard, Natalina Elliott, Sorcha O’Byrne, Myriam L. R. Haltalli, John E. Lawrence, Steven Lisgo, Petra Balogh, Kerstin B. Meyer, Elena Prigmore, Kirsty Ambridge, Mika Sarkin Jain, Mirjana Efremova, Keir Pickard, Thomas Creasey, Jaume Bacardit, Deborah Henderson, Jonathan Coxhead, Andrew Filby, Rafiqul Hussain, David Dixon, David McDonald, Dorin-Mirel Popescu, Monika S. Kowalczyk, Bo Li, Orr Ashenberg, Marcin Tabaka, Danielle Dionne, Timothy L. Tickle, Michal Slyper, Orit Rozenblatt-Rosen, Aviv Regev, Sam Behjati, Elisa Laurenti, Nicola K. Wilson, Anindita Roy, Berthold Göttgens, Irene Roberts, Sarah A. Teichmann and Muzlifah Haniffa

A single sulfatase is required to access colonic mucin by a gut bacterium pp. 332-337

Ana S. Luis, Chunsheng Jin, Gabriel Vasconcelos Pereira, Robert W. P. Glowacki, Sadie R. Gugel, Shaleni Singh, Dominic P. Byrne, Nicholas A. Pudlo, James A. London, Arnaud Baslé, Mark Reihill, Stefan Oscarson, Patrick A. Eyers, Mirjam Czjzek, Gurvan Michel, Tristan Barbeyron, Edwin A. Yates, Gunnar C. Hansson, Niclas G. Karlsson, Alan Cartmell and Eric C. Martens

Burden and characteristics of COVID-19 in the United States during 2020 pp. 338-341

Sen Pei, Teresa K. Yamana, Sasikiran Kandula, Marta Galanti and Jeffrey Shaman

Lectins enhance SARS-CoV-2 infection and influence neutralizing antibodies pp. 342-347

Florian A. Lempp, Leah B. Soriaga, Martin Montiel-Ruiz, Fabio Benigni, Julia Noack, Young-Jun Park, Siro Bianchi, Alexandra C. Walls, John E. Bowen, Jiayi Zhou, Hannah Kaiser, Anshu Joshi, Maria Agostini, Marcel Meury, Exequiel Dellota, Stefano Jaconi, Elisabetta Cameroni, Javier Martinez-Picado, Júlia Vergara-Alert, Nuria Izquierdo-Useros, Herbert W. Virgin, Antonio Lanzavecchia, David Veesler, Lisa A. Purcell, Amalio Telenti and Davide Corti

Biologically informed deep neural network for prostate cancer discovery pp. 348-352

Haitham A. Elmarakeby, Justin Hwang, Rand Arafeh, Jett Crowdis, Sydney Gang, David Liu, Saud H. AlDubayan, Keyan Salari, Steven Kregel, Camden Richter, Taylor E. Arnoff, Jihye Park, William C. Hahn and Eliezer M. Van Allen

Circadian autophagy drives iTRF-mediated longevity pp. 353-358

Matt Ulgherait, Adil M. Midoun, Scarlet J. Park, Jared A. Gatto, Samantha J. Tener, Julia Siewert, Naomi Klickstein, Julie C. Canman, William W. Ja and Mimi Shirasu-Hiza

Structure-based classification of tauopathies pp. 359-363

Yang Shi, Wenjuan Zhang, Yang Yang, Alexey G. Murzin, Benjamin Falcon, Abhay Kotecha, Mike Beers, Airi Tarutani, Fuyuki Kametani, Holly J. Garringer, Ruben Vidal, Grace I. Hallinan, Tammaryn Lashley, Yuko Saito, Shigeo Murayama, Mari Yoshida, Hidetomo Tanaka, Akiyoshi Kakita, Takeshi Ikeuchi, Andrew C. Robinson, David M. A. Mann, Gabor G. Kovacs, Tamas Revesz, Bernardino Ghetti, Masato Hasegawa, Michel Goedert and Sjors H. W. Scheres

Structure and assembly of the mammalian mitochondrial supercomplex CIII2CIV pp. 364-367

Irene Vercellino and Leonid A. Sazanov

Structural basis of human transcription–DNA repair coupling pp. 368-372

Goran Kokic, Felix R. Wagner, Aleksandar Chernev, Henning Urlaub and Patrick Cramer

Beware survivorship bias in advice on science careers pp. 373-374

Dave Hemprich-Bennett, Dani Rabaiotti and Emma Kennedy

How Latin American researchers suffer in science pp. 374-375

Ana M. Valenzuela-Toro and Mariana Viglino

Serving science and the Church as the Pope’s astronomer pp. 378-378

Chris Woolston

2021, volume 598, articles 7879

China’s data-driven dream to overhaul health care pp. S1-S3

Sarah O’Meara

COVID’s lessons for climate, sustainability and more from Our World in Data pp. 9-9

Hannah Ritchie

Illegal mining in the Amazon hits record high amid Indigenous protests pp. 15-16

Jeff Tollefson

High-profile autism genetics project paused amid backlash pp. 17-18

Katharine Sanderson

University under pressure to rehire scientist acquitted of hiding China links pp. 18-19

Nidhi Subbaraman

China’s clampdown on fake-paper factories picks up speed pp. 19-20

Holly Else

China’s pledge on overseas coal — by the numbers pp. 20-21

Quirin Schiermeier

This is what a solid made of electrons looks like pp. 21-21

Davide Castelvecchi

How the world’s biggest brain maps could transform neuroscience pp. 22-25

Alison Abbott

Reboot AI with human values pp. 27-28

Reema Patel

Ocean politics, DNA history and the climate experiment: Books in brief pp. 28-28

Andrew Robinson

Deploy heat officers, policies and metrics pp. 29-31

Ladd Keith, Sara Meerow, David M. Hondula, V. Kelly Turner and James C. Arnott

Fund natural-history museums, not de-extinction pp. 32-32

Corrie S. Moreau and Jessica L. Ware

Remembering a giant of chemical crystallography pp. 32-32

Martin Egli and Shuguang Zhang

Poor planning compounded European flooding catastrophes pp. 32-32

Alik Ismail-Zadeh

Sports concussions: sex differences in outcome are not a biological given pp. 32-32

Christina L. Master, Kristy Arbogast and Steven Broglio

A census of cell types in the brain’s motor cortex pp. 33-34

Johan Winnubst and Silvia Arber

Platinum catalysts strained controllably by size-changing nanocubes pp. 35-37

Sylvain Brimaud

Delayed global warming could reduce human exposure to cyclones pp. 35-35

Abigail Klopper

Tumours block protective muscle and nerve signals to cause cachexia pp. 37-38

Teresa A. Zimmers

Mechanical computing pp. 39-48

Hiromi Yasuda, Philip R. Buskohl, Andrew Gillman, Todd D. Murphey, Susan Stepney, Richard A. Vaia and Jordan R. Raney

Fine-regolith production on asteroids controlled by rock porosity pp. 49-52

S. Cambioni, M. Delbo, G. Poggiali, C. Avdellidou, A. J. Ryan, J. D. P. Deshapriya, E. Asphaug, R.-L. Ballouz, M. A. Barucci, C. A. Bennett, W. F. Bottke, J. R. Brucato, K. N. Burke, E. Cloutis, D. N. DellaGiustina, J. P. Emery, B. Rozitis, K. J. Walsh and D. S. Lauretta

Quantum anomalous Hall octet driven by orbital magnetism in bilayer graphene pp. 53-58

Fabian R. Geisenhof, Felix Winterer, Anna M. Seiler, Jakob Lenz, Tianyi Xu, Fan Zhang and R. Thomas Weitz

Topological complex-energy braiding of non-Hermitian bands pp. 59-64

Kai Wang, Avik Dutt, Charles C. Wojcik and Shanhui Fan

Colorimetric histology using plasmonically active microscope slides pp. 65-71

Eugeniu Balaur, Sandra O’ Toole, Alex J. Spurling, G. Bruce Mann, Belinda Yeo, Kate Harvey, Catherine Sadatnajafi, Eric Hanssen, Jacqueline Orian, Keith A. Nugent, Belinda S. Parker and Brian Abbey

A crystalline tri-thorium cluster with σ-aromatic metal–metal bonding pp. 72-75

Josef T. Boronski, John A. Seed, David Hunger, Adam W. Woodward, Joris Slageren, Ashley J. Wooles, Louise S. Natrajan, Nikolas Kaltsoyannis and Stephen T. Liddle

Mastering the surface strain of platinum catalysts for efficient electrocatalysis pp. 76-81

Tianou He, Weicong Wang, Fenglei Shi, Xiaolong Yang, Xiang Li, Jianbo Wu, Yadong Yin and Mingshang Jin

Hemispheric black carbon increase after the 13th-century Māori arrival in New Zealand pp. 82-85

Joseph R. McConnell, Nathan J. Chellman, Robert Mulvaney, Sabine Eckhardt, Andreas Stohl, Gill Plunkett, Sepp Kipfstuhl, Johannes Freitag, Elisabeth Isaksson, Kelly E. Gleason, Sandra O. Brugger, David B. McWethy, Nerilie J. Abram, Pengfei Liu and Alberto J. Aristarain

A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex pp. 103-110

Zizhen Yao, Hanqing Liu, Fangming Xie, Stephan Fischer, Ricky S. Adkins, Andrew I. Aldridge, Seth A. Ament, Anna Bartlett, M. Margarita Behrens, Koen Berge, Darren Bertagnolli, Hector Roux Bézieux, Tommaso Biancalani, A. Sina Booeshaghi, Héctor Corrada Bravo, Tamara Casper, Carlo Colantuoni, Jonathan Crabtree, Heather Creasy, Kirsten Crichton, Megan Crow, Nick Dee, Elizabeth L. Dougherty, Wayne I. Doyle, Sandrine Dudoit, Rongxin Fang, Victor Felix, Olivia Fong, Michelle Giglio, Jeff Goldy, Mike Hawrylycz, Brian R. Herb, Ronna Hertzano, Xiaomeng Hou, Qiwen Hu, Jayaram Kancherla, Matthew Kroll, Kanan Lathia, Yang Eric Li, Jacinta D. Lucero, Chongyuan Luo, Anup Mahurkar, Delissa McMillen, Naeem M. Nadaf, Joseph R. Nery, Thuc Nghi Nguyen, Sheng-Yong Niu, Vasilis Ntranos, Joshua Orvis, Julia K. Osteen, Thanh Pham, Antonio Pinto-Duarte, Olivier Poirion, Sebastian Preissl, Elizabeth Purdom, Christine Rimorin, Davide Risso, Angeline C. Rivkin, Kimberly Smith, Kelly Street, Josef Sulc, Valentine Svensson, Michael Tieu, Amy Torkelson, Herman Tung, Eeshit Dhaval Vaishnav, Charles R. Vanderburg, Cindy Velthoven, Xinxin Wang, Owen R. White, Z. Josh Huang, Peter V. Kharchenko, Lior Pachter, John Ngai, Aviv Regev, Bosiljka Tasic, Joshua D. Welch, Jesse Gillis, Evan Z. Macosko, Bing Ren, Joseph R. Ecker, Hongkui Zeng and Eran A. Mukamel

Comparative cellular analysis of motor cortex in human, marmoset and mouse pp. 111-119

Trygve E. Bakken, Nikolas L. Jorstad, Qiwen Hu, Blue B. Lake, Wei Tian, Brian E. Kalmbach, Megan Crow, Rebecca D. Hodge, Fenna M. Krienen, Staci A. Sorensen, Jeroen Eggermont, Zizhen Yao, Brian D. Aevermann, Andrew I. Aldridge, Anna Bartlett, Darren Bertagnolli, Tamara Casper, Rosa G. Castanon, Kirsten Crichton, Tanya L. Daigle, Rachel Dalley, Nick Dee, Nikolai Dembrow, Dinh Diep, Song-Lin Ding, Weixiu Dong, Rongxin Fang, Stephan Fischer, Melissa Goldman, Jeff Goldy, Lucas T. Graybuck, Brian R. Herb, Xiaomeng Hou, Jayaram Kancherla, Matthew Kroll, Kanan Lathia, Baldur Lew, Yang Eric Li, Christine S. Liu, Hanqing Liu, Jacinta D. Lucero, Anup Mahurkar, Delissa McMillen, Jeremy A. Miller, Marmar Moussa, Joseph R. Nery, Philip R. Nicovich, Sheng-Yong Niu, Joshua Orvis, Julia K. Osteen, Scott Owen, Carter R. Palmer, Thanh Pham, Nongluk Plongthongkum, Olivier Poirion, Nora M. Reed, Christine Rimorin, Angeline Rivkin, William J. Romanow, Adriana E. Sedeño-Cortés, Kimberly Siletti, Saroja Somasundaram, Josef Sulc, Michael Tieu, Amy Torkelson, Herman Tung, Xinxin Wang, Fangming Xie, Anna Marie Yanny, Renee Zhang, Seth A. Ament, M. Margarita Behrens, Hector Corrada Bravo, Jerold Chun, Alexander Dobin, Jesse Gillis, Ronna Hertzano, Patrick R. Hof, Thomas Höllt, Gregory D. Horwitz, C. Dirk Keene, Peter V. Kharchenko, Andrew L. Ko, Boudewijn P. Lelieveldt, Chongyuan Luo, Eran A. Mukamel, António Pinto-Duarte, Sebastian Preissl, Aviv Regev, Bing Ren, Richard H. Scheuermann, Kimberly Smith, William J. Spain, Owen R. White, Christof Koch, Michael Hawrylycz, Bosiljka Tasic, Evan Z. Macosko, Steven A. McCarroll, Jonathan T. Ting, Hongkui Zeng, Kun Zhang, Guoping Feng, Joseph R. Ecker, Sten Linnarsson and Ed S. Lein

DNA methylation atlas of the mouse brain at single-cell resolution pp. 120-128

Hanqing Liu, Jingtian Zhou, Wei Tian, Chongyuan Luo, Anna Bartlett, Andrew Aldridge, Jacinta Lucero, Julia K. Osteen, Joseph R. Nery, Huaming Chen, Angeline Rivkin, Rosa G. Castanon, Ben Clock, Yang Eric Li, Xiaomeng Hou, Olivier B. Poirion, Sebastian Preissl, Antonio Pinto-Duarte, Carolyn O’Connor, Lara Boggeman, Conor Fitzpatrick, Michael Nunn, Eran A. Mukamel, Zhuzhu Zhang, Edward M. Callaway, Bing Ren, Jesse R. Dixon, M. Margarita Behrens and Joseph R. Ecker

An atlas of gene regulatory elements in adult mouse cerebrum pp. 129-136

Yang Eric Li, Sebastian Preissl, Xiaomeng Hou, Ziyang Zhang, Kai Zhang, Yunjiang Qiu, Olivier B. Poirion, Bin Li, Joshua Chiou, Hanqing Liu, Antonio Pinto-Duarte, Naoki Kubo, Xiaoyu Yang, Rongxin Fang, Xinxin Wang, Jee Yun Han, Jacinta Lucero, Yiming Yan, Michael Miller, Samantha Kuan, David Gorkin, Kyle J. Gaulton, Yin Shen, Michael Nunn, Eran A. Mukamel, M. Margarita Behrens, Joseph R. Ecker and Bing Ren

Spatially resolved cell atlas of the mouse primary motor cortex by MERFISH pp. 137-143

Meng Zhang, Stephen W. Eichhorn, Brian Zingg, Zizhen Yao, Kaelan Cotter, Hongkui Zeng, Hongwei Dong and Xiaowei Zhuang

Phenotypic variation of transcriptomic cell types in mouse motor cortex pp. 144-150

Federico Scala, Dmitry Kobak, Matteo Bernabucci, Yves Bernaerts, Cathryn René Cadwell, Jesus Ramon Castro, Leonard Hartmanis, Xiaolong Jiang, Sophie Laturnus, Elanine Miranda, Shalaka Mulherkar, Zheng Huan Tan, Zizhen Yao, Hongkui Zeng, Rickard Sandberg, Philipp Berens and Andreas S. Tolias

Human neocortical expansion involves glutamatergic neuron diversification pp. 151-158

Jim Berg, Staci A. Sorensen, Jonathan T. Ting, Jeremy A. Miller, Thomas Chartrand, Anatoly Buchin, Trygve E. Bakken, Agata Budzillo, Nick Dee, Song-Lin Ding, Nathan W. Gouwens, Rebecca D. Hodge, Brian Kalmbach, Changkyu Lee, Brian R. Lee, Lauren Alfiler, Katherine Baker, Eliza Barkan, Allison Beller, Kyla Berry, Darren Bertagnolli, Kris Bickley, Jasmine Bomben, Thomas Braun, Krissy Brouner, Tamara Casper, Peter Chong, Kirsten Crichton, Rachel Dalley, Rebecca Frates, Tsega Desta, Samuel Dingman Lee, Florence D’Orazi, Nadezhda Dotson, Tom Egdorf, Rachel Enstrom, Colin Farrell, David Feng, Olivia Fong, Szabina Furdan, Anna A. Galakhova, Clare Gamlin, Amanda Gary, Alexandra Glandon, Jeff Goldy, Melissa Gorham, Natalia A. Goriounova, Sergey Gratiy, Lucas Graybuck, Hong Gu, Kristen Hadley, Nathan Hansen, Tim S. Heistek, Alex M. Henry, Djai B. Heyer, DiJon Hill, Chris Hill, Madie Hupp, Tim Jarsky, Sara Kebede, Lisa Keene, Lisa Kim, Mean-Hwan Kim, Matthew Kroll, Caitlin Latimer, Boaz P. Levi, Katherine E. Link, Matthew Mallory, Rusty Mann, Desiree Marshall, Michelle Maxwell, Medea McGraw, Delissa McMillen, Erica Melief, Eline J. Mertens, Leona Mezei, Norbert Mihut, Stephanie Mok, Gabor Molnar, Alice Mukora, Lindsay Ng, Kiet Ngo, Philip R. Nicovich, Julie Nyhus, Gaspar Olah, Aaron Oldre, Victoria Omstead, Attila Ozsvar, Daniel Park, Hanchuan Peng, Trangthanh Pham, Christina A. Pom, Lydia Potekhina, Ramkumar Rajanbabu, Shea Ransford, David Reid, Christine Rimorin, Augustin Ruiz, David Sandman, Josef Sulc, Susan M. Sunkin, Aaron Szafer, Viktor Szemenyei, Elliot R. Thomsen, Michael Tieu, Amy Torkelson, Jessica Trinh, Herman Tung, Wayne Wakeman, Femke Waleboer, Katelyn Ward, René Wilbers, Grace Williams, Zizhen Yao, Jae-Geun Yoon, Costas Anastassiou, Anton Arkhipov, Pal Barzo, Amy Bernard, Charles Cobbs, Philip C. Witt Hamer, Richard G. Ellenbogen, Luke Esposito, Manuel Ferreira, Ryder P. Gwinn, Michael J. Hawrylycz, Patrick R. Hof, Sander Idema, Allan R. Jones, C. Dirk Keene, Andrew L. Ko, Gabe J. Murphy, Lydia Ng, Jeffrey G. Ojemann, Anoop P. Patel, John W. Phillips, Daniel L. Silbergeld, Kimberly Smith, Bosiljka Tasic, Rafael Yuste, Idan Segev, Christiaan P. J. Kock, Huibert D. Mansvelder, Gabor Tamas, Hongkui Zeng, Christof Koch and Ed S. Lein

Cellular anatomy of the mouse primary motor cortex pp. 159-166

Rodrigo Muñoz-Castañeda, Brian Zingg, Katherine S. Matho, Xiaoyin Chen, Quanxin Wang, Nicholas N. Foster, Anan Li, Arun Narasimhan, Karla E. Hirokawa, Bingxing Huo, Samik Bannerjee, Laura Korobkova, Chris Sin Park, Young-Gyun Park, Michael S. Bienkowski, Uree Chon, Diek W. Wheeler, Xiangning Li, Yun Wang, Maitham Naeemi, Peng Xie, Lijuan Liu, Kathleen Kelly, Xu An, Sarojini M. Attili, Ian Bowman, Anastasiia Bludova, Ali Cetin, Liya Ding, Rhonda Drewes, Florence D’Orazi, Corey Elowsky, Stephan Fischer, William Galbavy, Lei Gao, Jesse Gillis, Peter A. Groblewski, Lin Gou, Joel D. Hahn, Joshua T. Hatfield, Houri Hintiryan, Junxiang Jason Huang, Hideki Kondo, Xiuli Kuang, Philip Lesnar, Xu Li, Yaoyao Li, Mengkuan Lin, Darrick Lo, Judith Mizrachi, Stephanie Mok, Philip R. Nicovich, Ramesh Palaniswamy, Jason Palmer, Xiaoli Qi, Elise Shen, Yu-Chi Sun, Huizhong W. Tao, Wayne Wakemen, Yimin Wang, Shenqin Yao, Jing Yuan, Huiqing Zhan, Muye Zhu, Lydia Ng, Li I. Zhang, Byung Kook Lim, Michael Hawrylycz, Hui Gong, James C. Gee, Yongsoo Kim, Kwanghun Chung, X. William Yang, Hanchuan Peng, Qingming Luo, Partha P. Mitra, Anthony M. Zador, Hongkui Zeng, Giorgio A. Ascoli, Z. Josh Huang, Pavel Osten, Julie A. Harris and Hong-Wei Dong

Epigenomic diversity of cortical projection neurons in the mouse brain pp. 167-173

Zhuzhu Zhang, Jingtian Zhou, Pengcheng Tan, Yan Pang, Angeline C. Rivkin, Megan A. Kirchgessner, Elora Williams, Cheng-Ta Lee, Hanqing Liu, Alexis D. Franklin, Paula Assakura Miyazaki, Anna Bartlett, Andrew I. Aldridge, Minh Vu, Lara Boggeman, Conor Fitzpatrick, Joseph R. Nery, Rosa G. Castanon, Mohammad Rashid, Matthew W. Jacobs, Tony Ito-Cole, Carolyn O’Connor, António Pinto-Duartec, Bertha Dominguez, Jared B. Smith, Sheng-Yong Niu, Kuo-Fen Lee, Xin Jin, Eran A. Mukamel, M. Margarita Behrens, Joseph R. Ecker and Edward M. Callaway

Morphological diversity of single neurons in molecularly defined cell types pp. 174-181

Hanchuan Peng, Peng Xie, Lijuan Liu, Xiuli Kuang, Yimin Wang, Lei Qu, Hui Gong, Shengdian Jiang, Anan Li, Zongcai Ruan, Liya Ding, Zizhen Yao, Chao Chen, Mengya Chen, Tanya L. Daigle, Rachel Dalley, Zhangcan Ding, Yanjun Duan, Aaron Feiner, Ping He, Chris Hill, Karla E. Hirokawa, Guodong Hong, Lei Huang, Sara Kebede, Hsien-Chi Kuo, Rachael Larsen, Phil Lesnar, Longfei Li, Qi Li, Xiangning Li, Yaoyao Li, Yuanyuan Li, An Liu, Donghuan Lu, Stephanie Mok, Lydia Ng, Thuc Nghi Nguyen, Qiang Ouyang, Jintao Pan, Elise Shen, Yuanyuan Song, Susan M. Sunkin, Bosiljka Tasic, Matthew B. Veldman, Wayne Wakeman, Wan Wan, Peng Wang, Quanxin Wang, Tao Wang, Yaping Wang, Feng Xiong, Wei Xiong, Wenjie Xu, Min Ye, Lulu Yin, Yang Yu, Jia Yuan, Jing Yuan, Zhixi Yun, Shaoqun Zeng, Shichen Zhang, Sujun Zhao, Zijun Zhao, Zhi Zhou, Z. Josh Huang, Luke Esposito, Michael J. Hawrylycz, Staci A. Sorensen, X. William Yang, Yefeng Zheng, Zhongze Gu, Wei Xie, Christof Koch, Qingming Luo, Julie A. Harris, Yun Wang and Hongkui Zeng

Genetic dissection of the glutamatergic neuron system in cerebral cortex pp. 182-187

Katherine S. Matho, Dhananjay Huilgol, William Galbavy, Miao He, Gukhan Kim, Xu An, Jiangteng Lu, Priscilla Wu, Daniela J. Bella, Ashwin S. Shetty, Ramesh Palaniswamy, Joshua Hatfield, Ricardo Raudales, Arun Narasimhan, Eric Gamache, Jesse M. Levine, Jason Tucciarone, Eric Szelenyi, Julie A. Harris, Partha P. Mitra, Pavel Osten, Paola Arlotta and Z. Josh Huang

The mouse cortico–basal ganglia–thalamic network pp. 188-194

Nicholas N. Foster, Joshua Barry, Laura Korobkova, Luis Garcia, Lei Gao, Marlene Becerra, Yasmine Sherafat, Bo Peng, Xiangning Li, Jun-Hyeok Choi, Lin Gou, Brian Zingg, Sana Azam, Darrick Lo, Neda Khanjani, Bin Zhang, Jim Stanis, Ian Bowman, Kaelan Cotter, Chunru Cao, Seita Yamashita, Amanda Tugangui, Anan Li, Tao Jiang, Xueyan Jia, Zhao Feng, Sarvia Aquino, Hyun-Seung Mun, Muye Zhu, Anthony Santarelli, Nora L. Benavidez, Monica Song, Gordon Dan, Marina Fayzullina, Sarah Ustrell, Tyler Boesen, David L. Johnson, Hanpeng Xu, Michael S. Bienkowski, X. William Yang, Hui Gong, Michael S. Levine, Ian Wickersham, Qingming Luo, Joel D. Hahn, Byung Kook Lim, Li I. Zhang, Carlos Cepeda, Houri Hintiryan and Hong-Wei Dong

Isoform cell-type specificity in the mouse primary motor cortex pp. 195-199

A. Sina Booeshaghi, Zizhen Yao, Cindy Velthoven, Kimberly Smith, Bosiljka Tasic, Hongkui Zeng and Lior Pachter

An atlas of cortical arealization identifies dynamic molecular signatures pp. 200-204

Aparna Bhaduri, Carmen Sandoval-Espinosa, Marcos Otero-Garcia, Irene Oh, Raymund Yin, Ugomma C. Eze, Tomasz J. Nowakowski and Arnold R. Kriegstein

Single-cell epigenomics reveals mechanisms of human cortical development pp. 205-213

Ryan S. Ziffra, Chang N. Kim, Jayden M. Ross, Amy Wilfert, Tychele N. Turner, Maximilian Haeussler, Alex M. Casella, Pawel F. Przytycki, Kathleen C. Keough, David Shin, Derek Bogdanoff, Anat Kreimer, Katherine S. Pollard, Seth A. Ament, Evan E. Eichler, Nadav Ahituv and Tomasz J. Nowakowski

A transcriptomic atlas of mouse cerebellar cortex comprehensively defines cell types pp. 214-219

Velina Kozareva, Caroline Martin, Tomas Osorno, Stephanie Rudolph, Chong Guo, Charles Vanderburg, Naeem Nadaf, Aviv Regev, Wade G. Regehr and Evan Macosko

Academia’s ableist culture laid bare pp. 221-223

Kendall Powell

Colour me better: fixing figures for colour blindness pp. 224-225

Alla Katsnelson

The Māori meeting house that’s also a research lab pp. 228-228

James Mitchell Crow