How the cGAS–STING system links inflammation and cognitive decline

Bart J. L. Eggen ()

Nature, 2023, vol. 620, issue 7973, 280-282

Abstract: When DNA is misplaced inside cells, the cGAS–STING molecular system triggers inflammation. It emerges that stimulation of this mechanism in microglial cells of the brain during ageing contributes to cognitive decline.

Keywords: Ageing; Immunology; Neurodegeneration; Neuroscience (search for similar items in EconPapers)
Date: 2023
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DOI: 10.1038/d41586-023-02240-1

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