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2012, volume 489, articles 7417

Chronic obstructive pulmonary disease pp. S1-S1

Herb Brody

Health impact: Breathless pp. S2-S3

Amber Dance

Biochemistry: A radical treatment pp. S4-S6

Ken Garber

Perspective: How can genetics help? pp. S7-S7

Edwin K. Silverman

Diagnosis: To catch a killer pp. S8-S9

Cassandra Willyard

Nutrition: The vitamin D complex pp. S10-S11

Thea Singer

Devices: Artificial inspiration pp. S12-S14

Elie Dolgin

Perspective: Clues, not conclusions pp. S15-S15

Steven R. Duncan

Therapeutics: Strength in numbers pp. S16-S17

Duncan Graham-Rowe

Public health: Where there's smoke pp. S18-S20

Virginia Hughes

It is time for full disclosure of author contributions pp. 475-475

Sebastian Frische

Researchers campaign to free jailed Russian chemist pp. 481-482

Quirin Schiermeier

Chemical society tried to block business competitor pp. 482-483

Eugenie Samuel Reich

Rat study sparks GM furore pp. 484-484

Declan Butler

China buys US sequencing firm pp. 485-486

Monya Baker

Open-access deal for particle physics pp. 486-486

Richard Van Noorden

US science: The Obama experiment pp. 488-492

Jeff Tollefson

Politicians should think like scientists pp. 493-494

Rush Holt

Know your representatives pp. 494-495

Lawrence Goldstein

Honour the helpful pp. 496-497

Alexander Oettl

Biography: The scientist within pp. 498-499

Richard Holmes

Food science: Digestive tracts pp. 500-500

Barbara Ketcham Wheaton

Statistics: Forecasting with finesse pp. 501-501

Paul Ormerod

Redirect research to control coffee pest pp. 502-502

Francisco Infante, Jeanneth Pérez and Fernando E. Vega

Follow the money on climate controversy pp. 502-502

Thomas E. DeCoursey

Green issues are catching on in China pp. 502-502

Qiang Wang, Xi Chen and Yi-Chong Xu

Rationality: Evidence must prevail pp. 502-502

David J. Hosken

Rationality: Science is not bad faith pp. 502-502

Andy Greenfield

Rationality: Religion defies understanding pp. 502-502

Andrew Blight

How the unicorn got its horn pp. 504-505

Heather Hendrickson and Paul B. Rainey

Spinning towards scalable circuits pp. 505-507

Lee C. Bassett and David D. Awschalom

Luck or reason pp. 507-508

Albert-László Barabási

Skin, heal thyself pp. 508-510

Elly M. Tanaka

'Cut and stick' ion gels pp. 510-511

Masashi Kawasaki and Yoshihiro Iwasa

When more is less pp. 511-512

Lei Jiang and Ralph J. DeBerardinis

Genomic analysis of a key innovation in an experimental Escherichia coli population pp. 513-518

Zachary D. Blount, Jeffrey E. Barrick, Carla J. Davidson and Richard E. Lenski

Cross-neutralization of influenza A viruses mediated by a single antibody loop pp. 526-532

Damian C. Ekiert, Arun K. Kashyap, John Steel, Adam Rubrum, Gira Bhabha, Reza Khayat, Jeong Hyun Lee, Michael A. Dillon, Ryann E. O’Neil, Aleksandr M. Faynboym, Michael Horowitz, Lawrence Horowitz, Andrew B. Ward, Peter Palese, Richard Webby, Richard A. Lerner, Ramesh R. Bhatt and Ian A. Wilson

No surviving evolved companions of the progenitor of SN 1006 pp. 533-536

Jonay I. González Hernández, Pilar Ruiz-Lapuente, Hugo M. Tabernero, David Montes, Ramon Canal, Javier Méndez and Luigi R. Bedin

Popularity versus similarity in growing networks pp. 537-540

Fragkiskos Papadopoulos, Maksim Kitsak, M. Ángeles Serrano, Marián Boguñá and Dmitri Krioukov

A single-atom electron spin qubit in silicon pp. 541-545

Jarryd J. Pla, Kuan Y. Tan, Juan P. Dehollain, Wee H. Lim, John J. L. Morton, David N. Jamieson, Andrew S. Dzurak and Andrea Morello

Ocean oxygenation in the wake of the Marinoan glaciation pp. 546-549

Swapan K. Sahoo, Noah J. Planavsky, Brian Kendall, Xinqiang Wang, Xiaoying Shi, Clint Scott, Ariel D. Anbar, Timothy W. Lyons and Ganqing Jiang

Response of salt-marsh carbon accumulation to climate change pp. 550-553

Matthew L. Kirwan and Simon M. Mudd

Delayed phenology and reduced fitness associated with climate change in a wild hibernator pp. 554-557

Jeffrey E. Lane, Loeske E. B. Kruuk, Anne Charmantier, Jan O. Murie and F. Stephen Dobson

Evidence for dietary change but not landscape use in South African early hominins pp. 558-560

Vincent Balter, José Braga, Philippe Télouk and J. Francis Thackeray

Skin shedding and tissue regeneration in African spiny mice (Acomys) pp. 561-565

Ashley W. Seifert, Stephen G. Kiama, Megan G. Seifert, Jacob R. Goheen, Todd M. Palmer and Malcolm Maden

Structural and genetic basis for development of broadly neutralizing influenza antibodies pp. 566-570

Daniel Lingwood, Patrick M. McTamney, Hadi M. Yassine, James R. R. Whittle, Xiaoti Guo, Jeffrey C. Boyington, Chih-Jen Wei and Gary J. Nabel

Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function pp. 571-575

Juan I. Garaycoechea, Gerry P. Crossan, Frederic Langevin, Maria Daly, Mark J. Arends and Ketan J. Patel

The Fun30 nucleosome remodeller promotes resection of DNA double-strand break ends pp. 576-580

Xuefeng Chen, Dandan Cui, Alma Papusha, Xiaotian Zhang, Chia-Dwo Chu, Jiangwu Tang, Kaifu Chen, Xuewen Pan and Grzegorz Ira

The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection pp. 581-584

Thomas Costelloe, Raphaël Louge, Nozomi Tomimatsu, Bipasha Mukherjee, Emmanuelle Martini, Basheer Khadaroo, Kenny Dubois, Wouter W. Wiegant, Agnès Thierry, Sandeep Burma, Haico van Attikum and Bertrand Llorente

Interaction landscape of membrane-protein complexes in Saccharomyces cerevisiae pp. 585-589

Mohan Babu, James Vlasblom, Shuye Pu, Xinghua Guo, Chris Graham, Björn D. M. Bean, Helen E. Burston, Franco J. Vizeacoumar, Jamie Snider, Sadhna Phanse, Vincent Fong, Yuen Yi C. Tam, Michael Davey, Olha Hnatshak, Navgeet Bajaj, Shamanta Chandran, Thanuja Punna, Constantine Christopolous, Victoria Wong, Analyn Yu, Gouqing Zhong, Joyce Li, Igor Stagljar, Elizabeth Conibear, Shoshana J. Wodak, Andrew Emili and Jack F. Greenblatt

Correction: Corrigendum: Peroxiredoxins are conserved markers of circadian rhythms pp. 590-590

Rachel S. Edgar, Edward W. Green, Yuwei Zhao, Gerben van Ooijen, Maria Olmedo, Ximing Qin, Yao Xu, Min Pan, Utham K. Valekunja, Kevin A. Feeney, Elizabeth S. Maywood, Michael H. Hastings, Nitin S. Baliga, Martha Merrow, Andrew J. Millar, Carl H. Johnson, Charalambos P. Kyriacou, John S. O’Neill and Akhilesh B. Reddy

Correction: Corrigendum: Constraints on future changes in climate and the hydrologic cycle pp. 590-590

Myles R. Allen and William J. Ingram

Erratum: Stereospecific binding of a disordered peptide segment mediates BK channel inactivation pp. 590-590

Vivian Gonzalez-Perez, Xu-Hui Zeng, Katie Henzler-Wildman and Christopher J. Lingle

Authorship: Who's on first? pp. 591-593

Amber Dance

Solidarity pp. 596-596

George Zebrowski

2012, volume 489, articles 7416

Intensified Arabian Sea tropical storms pp. E1-E2

Bin Wang, Shibin Xu and Liguang Wu

Evan et al. reply pp. E2-E3

Amato T. Evan, James P. Kossin, Chul ‘Eddy’ Chung and V. Ramanathan

Social networks can spread the Olympic effect pp. 337-337

Paul Ormerod

Studies slow the human DNA clock pp. 343-344

Ewen Callaway

Lab-animal flights squeezed pp. 344-345

Meredith Wadman

Retraction record rocks community pp. 346-347

David Cyranoski

UK technology-boost plan disappoints pp. 347-347

Ananyo Bhattacharya

The hidden threat of West Nile virus pp. 349-350

Amy Maxmen

Nano-safety studies urged in China pp. 350-350

Jane Qiu

Laser centre lights up eastern Europe pp. 351-351

Alison Abbott

Forest fires: Burn out pp. 352-354

Michelle Nijhuis

Neuroscience: Idle minds pp. 356-358

Kerri Smith

Plant perennials to save Africa's soils pp. 359-361

Jerry D. Glover, John P. Reganold and Cindy M. Cox

The United States must rejoin the SKA pp. 363-363

Anthony J. Beasley and Ethan J. Schreier

Military Science: The USSR's deadly secret pp. 364-365

Tim Trevan

Q&A: Collision creator pp. 366-366

Jascha Hoffman

Sustainability is key to development goals pp. 367-367

Manish Bapna

Arab science must help itself pp. 367-367

Mustafa al'Absi

Preprint servers: no author fees pp. 367-367

Ilya Kapovich

Preprint servers: follow arXiv's lead pp. 367-367

Tommy Ohlsson

Realizing Australia's bioenergy potential pp. 367-367

Luis C. Rodriguez, Alexander Herr and Michael H. O'Connor

Neil Armstrong (1930–2012) pp. 368-368

Roger D. Launius

Searching for the cosmic dawn pp. 370-371

Daniel Stark

Attention is more than meets the eye pp. 371-372

Alexandra Smolyanskaya and Richard T. Born

Liposomes derived from molecular vases pp. 372-374

Cyrus R. Safinya and Kai K. Ewert

A cooperative instinct pp. 374-375

Simon Gächter

The matryoshka effect pp. 375-376

Tom Nilges

Insects converge on resistance pp. 376-377

Noah K. Whiteman and Kailen A. Mooney

Bose glass and Mott glass of quasiparticles in a doped quantum magnet pp. 379-384

Rong Yu, Liang Yin, Neil S. Sullivan, J. S. Xia, Chao Huan, Armando Paduan-Filho, Nei F. Oliveira, Stephan Haas, Alexander Steppke, Corneliu F. Miclea, Franziska Weickert, Roman Movshovich, Eun-Deok Mun, Brian L. Scott, Vivien S. Zapf and Tommaso Roscilde

Autistic-like behaviour in Scn1a+/− mice and rescue by enhanced GABA-mediated neurotransmission pp. 385-390

Sung Han, Chao Tai, Ruth E. Westenbroek, Frank H. Yu, Christine S. Cheah, Gregory B. Potter, John L. Rubenstein, Todd Scheuer, Horacio O. de la Iglesia and William A. Catterall

An anatomically comprehensive atlas of the adult human brain transcriptome pp. 391-399

Michael J. Hawrylycz, Ed S. Lein, Angela L. Guillozet-Bongaarts, Elaine H. Shen, Lydia Ng, Jeremy A. Miller, Louie N. van de Lagemaat, Kimberly A. Smith, Amanda Ebbert, Zackery L. Riley, Chris Abajian, Christian F. Beckmann, Amy Bernard, Darren Bertagnolli, Andrew F. Boe, Preston M. Cartagena, M. Mallar Chakravarty, Mike Chapin, Jimmy Chong, Rachel A. Dalley, Barry David Daly, Chinh Dang, Suvro Datta, Nick Dee, Tim A. Dolbeare, Vance Faber, David Feng, David R. Fowler, Jeff Goldy, Benjamin W. Gregor, Zeb Haradon, David R. Haynor, John G. Hohmann, Steve Horvath, Robert E. Howard, Andreas Jeromin, Jayson M. Jochim, Marty Kinnunen, Christopher Lau, Evan T. Lazarz, Changkyu Lee, Tracy A. Lemon, Ling Li, Yang Li, John A. Morris, Caroline C. Overly, Patrick D. Parker, Sheana E. Parry, Melissa Reding, Joshua J. Royall, Jay Schulkin, Pedro Adolfo Sequeira, Clifford R. Slaughterbeck, Simon C. Smith, Andy J. Sodt, Susan M. Sunkin, Beryl E. Swanson, Marquis P. Vawter, Derric Williams, Paul Wohnoutka, H. Ronald Zielke, Daniel H. Geschwind, Patrick R. Hof, Stephen M. Smith, Christof Koch, Seth G. N. Grant and Allan R. Jones

Structural plasticity and dynamic selectivity of acid-sensing ion channel–spider toxin complexes pp. 400-405

Isabelle Baconguis and Eric Gouaux

A magnified young galaxy from about 500 million years after the Big Bang pp. 406-408

Wei Zheng, Marc Postman, Adi Zitrin, John Moustakas, Xinwen Shu, Stephanie Jouvel, Ole Høst, Alberto Molino, Larry Bradley, Dan Coe, Leonidas A. Moustakas, Mauricio Carrasco, Holland Ford, Narciso Benítez, Tod R. Lauer, Stella Seitz, Rychard Bouwens, Anton Koekemoer, Elinor Medezinski, Matthias Bartelmann, Tom Broadhurst, Megan Donahue, Claudio Grillo, Leopoldo Infante, Saurabh W. Jha, Daniel D. Kelson, Ofer Lahav, Doron Lemze, Peter Melchior, Massimo Meneghetti, Julian Merten, Mario Nonino, Sara Ogaz, Piero Rosati, Keiichi Umetsu and Arjen van der Wel

Pulsed electron paramagnetic resonance spectroscopy powered by a free-electron laser pp. 409-413

S. Takahashi, L.-C. Brunel, D. T. Edwards, J. van Tol, G. Ramian, S. Han and M. S. Sherwin

High-performance bulk thermoelectrics with all-scale hierarchical architectures pp. 414-418

Kanishka Biswas, Jiaqing He, Ivan D. Blum, Chun-I Wu, Timothy P. Hogan, David N. Seidman, Vinayak P. Dravid and Mercouri G. Kanatzidis

Oceanic nitrogen reservoir regulated by plankton diversity and ocean circulation pp. 419-422

Thomas Weber and Curtis Deutsch

Afternoon rain more likely over drier soils pp. 423-426

Christopher M. Taylor, Richard A. M. de Jeu, Françoise Guichard, Phil P. Harris and Wouter A. Dorigo

Spontaneous giving and calculated greed pp. 427-430

David G. Rand, Joshua D. Greene and Martin A. Nowak

Sex-specific volatile compounds influence microarthropod-mediated fertilization of moss pp. 431-433

Todd N. Rosenstiel, Erin E. Shortlidge, Andrea N. Melnychenko, James F. Pankow and Sarah M. Eppley

Attention deficits without cortical neuronal deficits pp. 434-437

Alexandre Zénon and Richard J. Krauzlis

Lrp4 is a retrograde signal for presynaptic differentiation at neuromuscular synapses pp. 438-442

Norihiro Yumoto, Natalie Kim and Steven J. Burden

Genome-wide association study indicates two novel resistance loci for severe malaria pp. 443-446

Christian Timmann, Thorsten Thye, Maren Vens, Jennifer Evans, Jürgen May, Christa Ehmen, Jürgen Sievertsen, Birgit Muntau, Gerd Ruge, Wibke Loag, Daniel Ansong, Sampson Antwi, Emanuel Asafo-Adjei, Samuel Blay Nguah, Kingsley Osei Kwakye, Alex Osei Yaw Akoto, Justice Sylverken, Michael Brendel, Kathrin Schuldt, Christina Loley, Andre Franke, Christian G. Meyer, Tsiri Agbenyega, Andreas Ziegler and Rolf D. Horstmann

A nuclear Argonaute promotes multigenerational epigenetic inheritance and germline immortality pp. 447-451

Bethany A. Buckley, Kirk B. Burkhart, Sam Guoping Gu, George Spracklin, Aaron Kershner, Heidi Fritz, Judith Kimble, Andrew Fire and Scott Kennedy

Set2 methylation of histone H3 lysine 36 suppresses histone exchange on transcribed genes pp. 452-455

Swaminathan Venkatesh, Michaela Smolle, Hua Li, Madelaine M. Gogol, Malika Saint, Shambhu Kumar, Krishnamurthy Natarajan and Jerry L. Workman

Structure of the haptoglobin–haemoglobin complex pp. 456-459

Christian Brix Folsted Andersen, Morten Torvund-Jensen, Marianne Jensby Nielsen, Cristiano Luis Pinto de Oliveira, Hans-Petter Hersleth, Niels Højmark Andersen, Jan Skov Pedersen, Gregers Rom Andersen and Søren Kragh Moestrup

Correction: Corrigendum: ‘Big Bang’ tomography as a new route to atomic-resolution electron tomography pp. 460-460

Dirk Van Dyck, Joerg R. Jinschek and Fu-Rong Chen

Erratum: Fractal morphology, imaging and mass spectrometry of single aerosol particles in flight pp. 460-460

N. D. Loh, C. Y. Hampton, A. V. Martin, D. Starodub, R. G. Sierra, A. Barty, A. Aquila, J. Schulz, L. Lomb, J. Steinbrener, R. L. Shoeman, S. Kassemeyer, C. Bostedt, J. Bozek, S. W. Epp, B. Erk, R. Hartmann, D. Rolles, A. Rudenko, B. Rudek, L. Foucar, N. Kimmel, G. Weidenspointner, G. Hauser, P. Holl, E. Pedersoli, M. Liang, M. S. Hunter, L. Gumprecht, N. Coppola, C. Wunderer, H. Graafsma, F. R. N. C. Maia, T. Ekeberg, M. Hantke, H. Fleckenstein, H. Hirsemann, K. Nass, T. A. White, H. J. Tobias, G. R. Farquar, W. H. Benner, S. P. Hau-Riege, C. Reich, A. Hartmann, H. Soltau, S. Marchesini, S. Bajt, M. Barthelmess, P. Bucksbaum, K. O. Hodgson, L. Strüder, J. Ullrich, M. Frank, I. Schlichting, H. N. Chapman and M. J. Bogan

Erratum: Structured spheres generated by an in-fibre fluid instability pp. 460-460

Joshua J. Kaufman, Guangming Tao, Soroush Shabahang, Esmaeil-Hooman Banaei, Daosheng S. Deng, Xiangdong Liang, Steven G. Johnson, Yoel Fink and Ayman F. Abouraddy

Erratum: Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy pp. 460-460

N. M. Archin, A. L. Liberty, A. D. Kashuba, S. K. Choudhary, J. D. Kuruc, A. M. Crooks, D. C. Parker, E. M. Anderson, M. F. Kearney, M. C. Strain, D. D. Richman, M. G. Hudgens, R. J. Bosch, J. M. Coffin, J. J. Eron, D. J. Hazuda and D. M. Margolis

Postdocs: A voice for the voiceless pp. 461-463

Karen Kaplan

Turning point: David Shelly pp. 463-463

Virginia Gewin

Without pp. 466-466

Fran Wilde

2012, volume 489, articles 7415

Predatory publishers are corrupting open access pp. 179-179

Jeffrey Beall

Ice loss shifts Arctic cycles pp. 185-186

Quirin Schiermeier

Europe on alert for flying invaders pp. 187-188

Declan Butler

EU battles over research billions pp. 188-189

Natasha Gilbert

Misconduct ruling is silent on intent pp. 189-190

Eugenie Samuel Reich

Cameras to focus on dark energy pp. 190-191

Eric Hand

India moves to tackle antibiotic resistance pp. 192-192

Erica Westly

Deep-sea research: Dive master pp. 194-196

Richard Monastersky

Microwave weapons: Wasted energy pp. 198-200

Sharon Weinberger

Predicting scientific success pp. 201-202

Daniel E. Acuna, Stefano Allesina and Konrad P. Kording

Well-funded investigators should receive extra scrutiny pp. 203-203

Jeremy M. Berg

Science fiction: The radium age pp. 204-205

Joshua Glenn

Q&A: Archivist of ice pp. 206-207

Jascha Hoffman

Physics: Modelling Feynman pp. 207-207

Daniel Cressey

Clarify the limits of climate models pp. 208-208

David A Stainforth and Leonard A. Smith

ENCODE leads the way on big data pp. 208-208

Mark Gerstein

Animal variants in sexual behaviour pp. 208-208

Rowan Hooper

A code of conduct for European scientists pp. 208-208

Nils Axelsen and Xavier Bosch

Wallace pioneered astrobiology too pp. 208-208

U. Kutschera

Mixed results for dieting monkeys pp. 210-211

Steven N. Austad

Drought and tropical soil emissions pp. 211-212

Cory C. Cleveland and Benjamin W. Sullivan

Poked to vote pp. 212-214

Sinan Aral

A biochemical messenger made easily pp. 214-215

Erik J. Sorensen

Dormant and restless skin stem cells pp. 215-217

Laura De Rosa and Michele De Luca

The rainforest's water pump pp. 217-218

Luiz E. O. C. Aragão

Gut microbes and health pp. 219-219

Claudia Lupp, Magdalena Skipper and Ursula Weiss

Diversity, stability and resilience of the human gut microbiota pp. 220-230

Catherine A. Lozupone, Jesse I. Stombaugh, Jeffrey I. Gordon, Janet K. Jansson and Rob Knight

Reciprocal interactions of the intestinal microbiota and immune system pp. 231-241

Craig L. Maynard, Charles O. Elson, Robin D. Hatton and Casey T. Weaver

Functional interactions between the gut microbiota and host metabolism pp. 242-249

Valentina Tremaroli and Fredrik Bäckhed

Genomic approaches to studying the human microbiota pp. 250-256

George M. Weinstock

Distinct contribution of stem and progenitor cells to epidermal maintenance pp. 257-262

Guilhem Mascré, Sophie Dekoninck, Benjamin Drogat, Khalil Kass Youssef, Sylvain Brohée, Panagiota A. Sotiropoulou, Benjamin D. Simons and Cédric Blanpain

RPN-6 determines C. elegans longevity under proteotoxic stress conditions pp. 263-268

David Vilchez, Ianessa Morantte, Zheng Liu, Peter M. Douglas, Carsten Merkwirth, Ana P. C. Rodrigues, Gerard Manning and Andrew Dillin

Quantum teleportation over 143 kilometres using active feed-forward pp. 269-273

Xiao-Song Ma, Thomas Herbst, Thomas Scheidl, Daqing Wang, Sebastian Kropatschek, William Naylor, Bernhard Wittmann, Alexandra Mech, Johannes Kofler, Elena Anisimova, Vadim Makarov, Thomas Jennewein, Rupert Ursin and Anton Zeilinger

Stabilization of Leidenfrost vapour layer by textured superhydrophobic surfaces pp. 274-277

Ivan U. Vakarelski, Neelesh A. Patankar, Jeremy O. Marston, Derek Y. C. Chan and Sigurdur T. Thoroddsen

Stereocontrolled organocatalytic synthesis of prostaglandin PGF2α in seven steps pp. 278-281

Graeme Coulthard, William Erb and Varinder K. Aggarwal

Observations of increased tropical rainfall preceded by air passage over forests pp. 282-285

D. V. Spracklen, S. R. Arnold and C. M. Taylor

Ploughing the deep sea floor pp. 286-289

Pere Puig, Miquel Canals, Joan B. Company, Jacobo Martín, David Amblas, Galderic Lastras, Albert Palanques and Antoni M. Calafat

Averting biodiversity collapse in tropical forest protected areas pp. 290-294

William F. Laurance, D. Carolina Useche, Julio Rendeiro, Margareta Kalka, Corey J. A. Bradshaw, Sean P. Sloan, Susan G. Laurance, Mason Campbell, Kate Abernethy, Patricia Alvarez, Victor Arroyo-Rodriguez, Peter Ashton, Julieta Benítez-Malvido, Allard Blom, Kadiri S. Bobo, Charles H. Cannon, Min Cao, Richard Carroll, Colin Chapman, Rosamond Coates, Marina Cords, Finn Danielsen, Bart De Dijn, Eric Dinerstein, Maureen A. Donnelly, David Edwards, Felicity Edwards, Nina Farwig, Peter Fashing, Pierre-Michel Forget, Mercedes Foster, George Gale, David Harris, Rhett Harrison, John Hart, Sarah Karpanty, W. John Kress, Jagdish Krishnaswamy, Willis Logsdon, Jon Lovett, William Magnusson, Fiona Maisels, Andrew R. Marshall, Deedra McClearn, Divya Mudappa, Martin R. Nielsen, Richard Pearson, Nigel Pitman, Jan van der Ploeg, Andrew Plumptre, John Poulsen, Mauricio Quesada, Hugo Rainey, Douglas Robinson, Christiane Roetgers, Francesco Rovero, Frederick Scatena, Christian Schulze, Douglas Sheil, Thomas Struhsaker, John Terborgh, Duncan Thomas, Robert Timm, J. Nicolas Urbina-Cardona, Karthikeyan Vasudevan, S. Joseph Wright, Juan Carlos Arias-G., Luzmila Arroyo, Mark Ashton, Philippe Auzel, Dennis Babaasa, Fred Babweteera, Patrick Baker, Olaf Banki, Margot Bass, Inogwabini Bila-Isia, Stephen Blake, Warren Brockelman, Nicholas Brokaw, Carsten A. Brühl, Sarayudh Bunyavejchewin, Jung-Tai Chao, Jerome Chave, Ravi Chellam, Connie J. Clark, José Clavijo, Robert Congdon, Richard Corlett, H. S. Dattaraja, Chittaranjan Dave, Glyn Davies, Beatriz de Mello Beisiegel, Rosa de Nazaré Paes da Silva, Anthony Di Fiore, Arvin Diesmos, Rodolfo Dirzo, Diane Doran-Sheehy, Mitchell Eaton, Louise Emmons, Alejandro Estrada, Corneille Ewango, Linda Fedigan, François Feer, Barbara Fruth, Jacalyn Giacalone Willis, Uromi Goodale, Steven Goodman, Juan C. Guix, Paul Guthiga, William Haber, Keith Hamer, Ilka Herbinger, Jane Hill, Zhongliang Huang, I Fang Sun, Kalan Ickes, Akira Itoh, Natália Ivanauskas, Betsy Jackes, John Janovec, Daniel Janzen, Mo Jiangming, Chen Jin, Trevor Jones, Hermes Justiniano, Elisabeth Kalko, Aventino Kasangaki, Timothy Killeen, Hen-biau King, Erik Klop, Cheryl Knott, Inza Koné, Enoka Kudavidanage, José Lahoz da Silva Ribeiro, John Lattke, Richard Laval, Robert Lawton, Miguel Leal, Mark Leighton, Miguel Lentino, Cristiane Leonel, Jeremy Lindsell, Lee Ling-Ling, K. Eduard Linsenmair, Elizabeth Losos, Ariel Lugo, Jeremiah Lwanga, Andrew L. Mack, Marlucia Martins, W. Scott McGraw, Roan McNab, Luciano Montag, Jo Myers Thompson, Jacob Nabe-Nielsen, Michiko Nakagawa, Sanjay Nepal, Marilyn Norconk, Vojtech Novotny, Sean O'Donnell, Muse Opiang, Paul Ouboter, Kenneth Parker, N. Parthasarathy, Kátia Pisciotta, Dewi Prawiradilaga, Catherine Pringle, Subaraj Rajathurai, Ulrich Reichard, Gay Reinartz, Katherine Renton, Glen Reynolds, Vernon Reynolds, Erin Riley, Mark-Oliver Rödel, Jessica Rothman, Philip Round, Shoko Sakai, Tania Sanaiotti, Tommaso Savini, Gertrud Schaab, John Seidensticker, Alhaji Siaka, Miles R. Silman, Thomas B. Smith, Samuel Soares de Almeida, Navjot Sodhi, Craig Stanford, Kristine Stewart, Emma Stokes, Kathryn E. Stoner, Raman Sukumar, Martin Surbeck, Mathias Tobler, Teja Tscharntke, Andrea Turkalo, Govindaswamy Umapathy, Merlijn van Weerd, Jorge Vega Rivera, Meena Venkataraman, Linda Venn, Carlos Verea, Carolina Volkmer de Castilho, Matthias Waltert, Benjamin Wang, David Watts, William Weber, Paige West, David Whitacre, Ken Whitney, David Wilkie, Stephen Williams, Debra D. Wright, Patricia Wright, Lu Xiankai, Pralad Yonzon and Franky Zamzani

A 61-million-person experiment in social influence and political mobilization pp. 295-298

Robert M. Bond, Christopher J. Fariss, Jason J. Jones, Adam D. I. Kramer, Cameron Marlow, Jaime E. Settle and James H. Fowler

Activity in motor–sensory projections reveals distributed coding in somatosensation pp. 299-303

Leopoldo Petreanu, Diego A. Gutnisky, Daniel Huber, Ning-long Xu, Dan H. O’Connor, Lin Tian, Loren Looger and Karel Svoboda

Increased proteasome activity in human embryonic stem cells is regulated by PSMD11 pp. 304-308

David Vilchez, Leah Boyer, Ianessa Morantte, Margaret Lutz, Carsten Merkwirth, Derek Joyce, Brian Spencer, Lesley Page, Eliezer Masliah, W. Travis Berggren, Fred H. Gage and Andrew Dillin

Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling pp. 309-312

Marcus Dühren- von Minden, Rudolf Übelhart, Dunja Schneider, Thomas Wossning, Martina P. Bach, Maike Buchner, Daniel Hofmann, Elena Surova, Marie Follo, Fabian Köhler, Hedda Wardemann, Katja Zirlik, Hendrik Veelken and Hassan Jumaa

HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle pp. 313-317

Matthew A. Deardorff, Masashige Bando, Ryuichiro Nakato, Erwan Watrin, Takehiko Itoh, Masashi Minamino, Katsuya Saitoh, Makiko Komata, Yuki Katou, Dinah Clark, Kathryn E. Cole, Elfride De Baere, Christophe Decroos, Nataliya Di Donato, Sarah Ernst, Lauren J. Francey, Yolanda Gyftodimou, Kyotaro Hirashima, Melanie Hullings, Yuuichi Ishikawa, Christian Jaulin, Maninder Kaur, Tohru Kiyono, Patrick M. Lombardi, Laura Magnaghi-Jaulin, Geert R. Mortier, Naohito Nozaki, Michael B. Petersen, Hiroyuki Seimiya, Victoria M. Siu, Yutaka Suzuki, Kentaro Takagaki, Jonathan J. Wilde, Patrick J. Willems, Claude Prigent, Gabriele Gillessen-Kaesbach, David W. Christianson, Frank J. Kaiser, Laird G. Jackson, Toru Hirota, Ian D. Krantz and Katsuhiko Shirahige

Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study pp. 318-321

Julie A. Mattison, George S. Roth, T. Mark Beasley, Edward M. Tilmont, April M. Handy, Richard L. Herbert, Dan L. Longo, David B. Allison, Jennifer E. Young, Mark Bryant, Dennis Barnard, Walter F. Ward, Wenbo Qi, Donald K. Ingram and Rafael de Cabo

Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts pp. 322-325

Yuji Shiba, Sarah Fernandes, Wei-Zhong Zhu, Dominic Filice, Veronica Muskheli, Jonathan Kim, Nathan J. Palpant, Jay Gantz, Kara White Moyes, Hans Reinecke, Benjamin Van Biber, Todd Dardas, John L. Mignone, Atsushi Izawa, Ramy Hanna, Mohan Viswanathan, Joseph D. Gold, Michael I. Kotlikoff, Narine Sarvazyan, Matthew W. Kay, Charles E. Murry and Michael A. Laflamme

Correction: Corrigendum: Recurrent network activity drives striatal synaptogenesis pp. 326-326

Yevgenia Kozorovitskiy, Arpiar Saunders, Caroline A. Johnson, Bradford B. Lowell and Bernardo L. Sabatini

Correction: Corrigendum: Biodiversity loss and its impact on humanity pp. 326-326

Bradley J. Cardinale, J. Emmett Duffy, Andrew Gonzalez, David U. Hooper, Charles Perrings, Patrick Venail, Anita Narwani, Georgina M. Mace, David Tilman, David A.Wardle, Ann P. Kinzig, Gretchen C. Daily, Michel Loreau, James B. Grace, Anne Larigauderie, Diane S. Srivastava and Shahid Naeem

Erratum: Non-invasive prenatal measurement of the fetal genome pp. 326-326

H. Christina Fan, Wei Gu, Jianbin Wang, Yair J. Blumenfeld, Yasser Y. El-Sayed and Stephen R. Quake

Erratum: An origin of the radio jet in M87 at the location of the central black hole pp. 326-326

Kazuhiro Hada, Akihiro Doi, Motoki Kino, Hiroshi Nagai, Yoshiaki Hagiwara and Noriyuki Kawaguchi

Working together pp. 327-328

Mary Anne Holmes

Turning point: Alberto Gonzalez Fairén pp. 328-328

Karen Kaplan

Communicant pp. 330-330

John Gilbey

2012, volume 489, articles 7414

We must be open about our mistakes pp. 7-7

Jim Woodgett

Alzheimer’s drugs take a new tack pp. 13-14

Ewen Callaway

India’s forest area in doubt pp. 14-15

Natasha Gilbert

Trade deal to curb generic-drug use pp. 16-17

Amy Maxmen

Electro-optic dye triggers ethics row pp. 17-17

Eugenie Samuel Reich

Databases fight funding cuts pp. 19-19

Monya Baker

Voyager’s long goodbye pp. 20-21

Ron Cowen

China's dinosaur hunter: The ground breaker pp. 22-25

Kerri Smith

Rethink chemical risk assessments pp. 27-28

George M. Gray and Joshua T. Cohen

Architecture: Life in stone pp. 29-30

Georgina Ferry

Technology: Baroque geekery pp. 30-31

Tim Boon

Q&A: Maths demystifier pp. 32-32

Jascha Hoffman

NASA bids are not a popularity contest pp. 33-33

Michael F. A'Hearn

Tourism ban won't help Indian tigers pp. 33-33

Ralf C. Buckley and H. S. Pabla

Tighten up Japan's stem-cell practices pp. 33-33

Hiroshi Ikegaya

Avoid constructing wind farms on peat pp. 33-33

Jo Smith, Dali Rani Nayak and Pete Smith

Improve sanitation on India's railways pp. 33-33

Abhishek Sharma, M. K. Unnikrishnan and Ankush Madaan

Martin Fleischmann (1927–2012) pp. 34-34

Philip Ball

A hard concept in soft matter pp. 36-37

Kenneth R. Shull

The lithium problem pp. 37-38

Garik Israelian

Lessons from heartbreak pp. 38-39

Aki Ejima

Brief but warm Antarctic summer pp. 39-40

Eric J. Steig

Separation by reconfiguration pp. 41-42

Robert W. Field

Outflows from the first quasars pp. 42-43

Daniel Mortlock

A protein engagement RING pp. 43-44

Christopher D. Lima and Brenda A. Schulman

Presenting ENCODE pp. 45-45

Magdalena Skipper, Ritu Dhand and Philip Campbell

ENCODE: The human encyclopaedia pp. 46-48

Brendan Maher

Lessons for big-data projects pp. 49-51

Ewan Birney

ENCODE explained pp. 52-54

Joseph R. Ecker, Wendy A. Bickmore, Inês Barroso, Jonathan K. Pritchard, Yoav Gilad and Eran Segal

The accessible chromatin landscape of the human genome pp. 75-82

Robert E. Thurman, Eric Rynes, Richard Humbert, Jeff Vierstra, Matthew T. Maurano, Eric Haugen, Nathan C. Sheffield, Andrew B. Stergachis, Hao Wang, Benjamin Vernot, Kavita Garg, Sam John, Richard Sandstrom, Daniel Bates, Lisa Boatman, Theresa K. Canfield, Morgan Diegel, Douglas Dunn, Abigail K. Ebersol, Tristan Frum, Erika Giste, Audra K. Johnson, Ericka M. Johnson, Tanya Kutyavin, Bryan Lajoie, Bum-Kyu Lee, Kristen Lee, Darin London, Dimitra Lotakis, Shane Neph, Fidencio Neri, Eric D. Nguyen, Hongzhu Qu, Alex P. Reynolds, Vaughn Roach, Alexias Safi, Minerva E. Sanchez, Amartya Sanyal, Anthony Shafer, Jeremy M. Simon, Lingyun Song, Shinny Vong, Molly Weaver, Yongqi Yan, Zhancheng Zhang, Zhuzhu Zhang, Boris Lenhard, Muneesh Tewari, Michael O. Dorschner, R. Scott Hansen, Patrick A. Navas, George Stamatoyannopoulos, Vishwanath R. Iyer, Jason D. Lieb, Shamil R. Sunyaev, Joshua M. Akey, Peter J. Sabo, Rajinder Kaul, Terrence S. Furey, Job Dekker, Gregory E. Crawford and John A. Stamatoyannopoulos

An expansive human regulatory lexicon encoded in transcription factor footprints pp. 83-90

Shane Neph, Jeff Vierstra, Andrew B. Stergachis, Alex P. Reynolds, Eric Haugen, Benjamin Vernot, Robert E. Thurman, Sam John, Richard Sandstrom, Audra K. Johnson, Matthew T. Maurano, Richard Humbert, Eric Rynes, Hao Wang, Shinny Vong, Kristen Lee, Daniel Bates, Morgan Diegel, Vaughn Roach, Douglas Dunn, Jun Neri, Anthony Schafer, R. Scott Hansen, Tanya Kutyavin, Erika Giste, Molly Weaver, Theresa Canfield, Peter Sabo, Miaohua Zhang, Gayathri Balasundaram, Rachel Byron, Michael J. MacCoss, Joshua M. Akey, M. A. Bender, Mark Groudine, Rajinder Kaul and John A. Stamatoyannopoulos

Architecture of the human regulatory network derived from ENCODE data pp. 91-100

Mark B. Gerstein, Anshul Kundaje, Manoj Hariharan, Stephen G. Landt, Koon-Kiu Yan, Chao Cheng, Xinmeng Jasmine Mu, Ekta Khurana, Joel Rozowsky, Roger Alexander, Renqiang Min, Pedro Alves, Alexej Abyzov, Nick Addleman, Nitin Bhardwaj, Alan P. Boyle, Philip Cayting, Alexandra Charos, David Z. Chen, Yong Cheng, Declan Clarke, Catharine Eastman, Ghia Euskirchen, Seth Frietze, Yao Fu, Jason Gertz, Fabian Grubert, Arif Harmanci, Preti Jain, Maya Kasowski, Phil Lacroute, Jing Leng, Jin Lian, Hannah Monahan, Henriette O’Geen, Zhengqing Ouyang, E. Christopher Partridge, Dorrelyn Patacsil, Florencia Pauli, Debasish Raha, Lucia Ramirez, Timothy E. Reddy, Brian Reed, Minyi Shi, Teri Slifer, Jing Wang, Linfeng Wu, Xinqiong Yang, Kevin Y. Yip, Gili Zilberman-Schapira, Serafim Batzoglou, Arend Sidow, Peggy J. Farnham, Richard M. Myers, Sherman M. Weissman and Michael Snyder

Landscape of transcription in human cells pp. 101-108

Sarah Djebali, Carrie A. Davis, Angelika Merkel, Alex Dobin, Timo Lassmann, Ali Mortazavi, Andrea Tanzer, Julien Lagarde, Wei Lin, Felix Schlesinger, Chenghai Xue, Georgi K. Marinov, Jainab Khatun, Brian A. Williams, Chris Zaleski, Joel Rozowsky, Maik Röder, Felix Kokocinski, Rehab F. Abdelhamid, Tyler Alioto, Igor Antoshechkin, Michael T. Baer, Nadav S. Bar, Philippe Batut, Kimberly Bell, Ian Bell, Sudipto Chakrabortty, Xian Chen, Jacqueline Chrast, Joao Curado, Thomas Derrien, Jorg Drenkow, Erica Dumais, Jacqueline Dumais, Radha Duttagupta, Emilie Falconnet, Meagan Fastuca, Kata Fejes-Toth, Pedro Ferreira, Sylvain Foissac, Melissa J. Fullwood, Hui Gao, David Gonzalez, Assaf Gordon, Harsha Gunawardena, Cedric Howald, Sonali Jha, Rory Johnson, Philipp Kapranov, Brandon King, Colin Kingswood, Oscar J. Luo, Eddie Park, Kimberly Persaud, Jonathan B. Preall, Paolo Ribeca, Brian Risk, Daniel Robyr, Michael Sammeth, Lorian Schaffer, Lei-Hoon See, Atif Shahab, Jorgen Skancke, Ana Maria Suzuki, Hazuki Takahashi, Hagen Tilgner, Diane Trout, Nathalie Walters, Huaien Wang, John Wrobel, Yanbao Yu, Xiaoan Ruan, Yoshihide Hayashizaki, Jennifer Harrow, Mark Gerstein, Tim Hubbard, Alexandre Reymond, Stylianos E. Antonarakis, Gregory Hannon, Morgan C. Giddings, Yijun Ruan, Barbara Wold, Piero Carninci, Roderic Guigó and Thomas R. Gingeras

The long-range interaction landscape of gene promoters pp. 109-113

Amartya Sanyal, Bryan R. Lajoie, Gaurav Jain and Job Dekker

Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis pp. 115-120

Anna Plechanovová, Ellis G. Jaffray, Michael H. Tatham, James H. Naismith and Ronald T. Hay

Observation of interstellar lithium in the low-metallicity Small Magellanic Cloud pp. 121-123

J. Christopher Howk, Nicolas Lehner, Brian D. Fields and Grant J. Mathews

No meridional plasma flow in the heliosheath transition region pp. 124-127

Robert B. Decker, Stamatios M. Krimigis, Edmond C. Roelof and Matthew E. Hill

Flexible metal-oxide devices made by room-temperature photochemical activation of sol–gel films pp. 128-132

Yong-Hoon Kim, Jae-Sang Heo, Tae-Hyeong Kim, Sungjun Park, Myung-Han Yoon, Jiwan Kim, Min Suk Oh, Gi-Ra Yi, Yong-Young Noh and Sung Kyu Park

Highly stretchable and tough hydrogels pp. 133-136

Jeong-Yun Sun, Xuanhe Zhao, Widusha R. K. Illeperuma, Ovijit Chaudhuri, Kyu Hwan Oh, David J. Mooney, Joost J. Vlassak and Zhigang Suo

Activation of old carbon by erosion of coastal and subsea permafrost in Arctic Siberia pp. 137-140

J. E. Vonk, L. Sánchez-García, B. E. van Dongen, V. Alling, D. Kosmach, A. Charkin, I. P. Semiletov, O. V. Dudarev, N. Shakhova, P. Roos, T. I. Eglinton, A. Andersson and Ö. Gustafsson

Recent Antarctic Peninsula warming relative to Holocene climate and ice-shelf history pp. 141-144

Robert Mulvaney, Nerilie J. Abram, Richard C. A. Hindmarsh, Carol Arrowsmith, Louise Fleet, Jack Triest, Louise C. Sime, Olivier Alemany and Susan Foord

Dopamine neurons modulate pheromone responses in Drosophila courtship learning pp. 145-149

Krystyna Keleman, Eleftheria Vrontou, Sebastian Krüttner, Jai Y. Yu, Amina Kurtovic-Kozaric and Barry J. Dickson

Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision pp. 150-154

Juan Song, Chun Zhong, Michael A. Bonaguidi, Gerald J. Sun, Derek Hsu, Yan Gu, Konstantinos Meletis, Z. Josh Huang, Shaoyu Ge, Grigori Enikolopov, Karl Deisseroth, Bernhard Luscher, Kimberly M. Christian, Guo-li Ming and Hongjun Song

Heterodimeric JAK–STAT activation as a mechanism of persistence to JAK2 inhibitor therapy pp. 155-159

Priya Koppikar, Neha Bhagwat, Outi Kilpivaara, Taghi Manshouri, Mazhar Adli, Todd Hricik, Fan Liu, Lindsay M. Saunders, Ann Mullally, Omar Abdel-Wahab, Laura Leung, Abby Weinstein, Sachie Marubayashi, Aviva Goel, Mithat Gönen, Zeev Estrov, Benjamin L. Ebert, Gabriela Chiosis, Stephen D. Nimer, Bradley E. Bernstein, Srdan Verstovsek and Ross L. Levine

Endogenous antigen tunes the responsiveness of naive B cells but not T cells pp. 160-164

Julie Zikherman, Ramya Parameswaran and Arthur Weiss

Collaborations: A single cog in a complex machine pp. 165-167

Sarah Kellogg

If only pp. 170-170

Tony Ballantyne