Damage prevention targeted

Dan Dominissini () and Chuan He ()
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Dan Dominissini: and at the Howard Hughes Medical Institute, University of Chicago, Chicago, Illinois 60637, USA.
Chuan He: and at the Howard Hughes Medical Institute, University of Chicago, Chicago, Illinois 60637, USA.

Nature, 2014, vol. 508, issue 7495, 191-192

Abstract: The MTH1 protein prevents oxidized nucleotides from being misincorporated into DNA. Two studies find that selective inhibition of MTH1 by small molecules suppresses tumour growth. See Articles p.215 & p.222

Date: 2014
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DOI: 10.1038/nature13221

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