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2022, volume 606, articles 7916

Unleashing the power of big data to guide precision medicine in China pp. S49-S51

Yvaine Ye

Nuclear power can help the democratic world achieve energy independence pp. 841-841

Nicolas Mazzucchi

Biden names former DARPA leader Arati Prabhakar as science adviser pp. 847-848

Jeff Tollefson

What Omicron’s BA.4 and BA.5 variants mean for the pandemic pp. 848-849

Ewen Callaway

Open-source language AI challenges big tech’s models pp. 850-851

Elizabeth Gibney

Crucial biodiversity summit will go ahead in Canada, not China: what scientists think pp. 851-851

Natasha Gilbert

How common is long COVID? Why studies give different answers pp. 852-853

Heidi Ledford

Many researchers say they’ll share data — but don’t pp. 853-853

Clare Watson

COVID antibody drugs have saved lives — so why aren’t they more popular? pp. 854-856

Asher Mullard

How the peanut trade prolonged slavery pp. 857-858

Amy Maxmen

Mental mapping, and the tragedy of water access: Books in brief pp. 858-858

Andrew Robinson

David A. Evans (1941–2022) pp. 859-859

Mark Lautens

Six research priorities to support corporate due-diligence policies pp. 861-863

Jorge Sellare, Jan Börner, Fritz Brugger, Rachael Garrett, Isabel Günther, Eva-Marie Meemken, Edoardo Maria Pelli, Linda Steinhübel and David Wuepper

Nigeria’s policymakers must prioritize One Health pp. 864-864

Tariq Oluwakunmi Agbabiaka and Madinat Abimbola Abdulkareem

Strengthen biosecurity when rewiring global food supply chains pp. 864-864

Alec P. Christie, David C. Aldridge, Belinda Gallardo, Seán Ó hÉigeartaigh, Silviu O. Petrovan and William J. Sutherland

Removing carbon dioxide: first, do no harm pp. 864-864

Ken Buesseler, Margaret Leinen and Kilaparti Ramakrishna

Layered material soaks up molecules to form an electron sieve pp. 865-866

Xi Ling

Bacterial envelope built to a peptidoglycan tune pp. 866-867

Michaël Deghelt and Jean-François Collet

Designer protein circuits enable safe cancer immunotherapy pp. 868-869

Mohamad Hamieh and Maria Themeli

Synthesis reveals unexpected biological targets of a traditional medicine pp. 869-870

Nicholas P. R. Onuska and Joshua G. Pierce

Mutation and tissue lineage lead to organ-specific cancer pp. 871-872

Emily N. Arner and W. Kimryn Rathmell

A repeating fast radio burst associated with a persistent radio source pp. 873-877

C.-H. Niu, K. Aggarwal, D. Li, X. Zhang, S. Chatterjee, C.-W. Tsai, W. Yu, C. J. Law, S. Burke-Spolaor, J. M. Cordes, Y.-K. Zhang, S. K. Ocker, J.-M. Yao, P. Wang, Y. Feng, Y. Niino, C. Bochenek, M. Cruces, L. Connor, J.-A. Jiang, S. Dai, R. Luo, G.-D. Li, C.-C. Miao, J.-R. Niu, R. Anna-Thomas, J. Sydnor, D. Stern, W.-Y. Wang, M. Yuan, Y.-L. Yue, D.-J. Zhou, Z. Yan, W.-W. Zhu and B. Zhang

Direct measurement of the 3He+ magnetic moments pp. 878-883

A. Schneider, B. Sikora, S. Dickopf, M. Müller, N. S. Oreshkina, A. Rischka, I. A. Valuev, S. Ulmer, J. Walz, Z. Harman, C. H. Keitel, A. Mooser and K. Blaum

Fault-tolerant operation of a logical qubit in a diamond quantum processor pp. 884-889

M. H. Abobeih, Y. Wang, J. Randall, S. J. H. Loenen, C. E. Bradley, M. Markham, D. J. Twitchen, B. M. Terhal and T. H. Taminiau

Ordered and tunable Majorana-zero-mode lattice in naturally strained LiFeAs pp. 890-895

Meng Li, Geng Li, Lu Cao, Xingtai Zhou, Xiancheng Wang, Changqing Jin, Ching-Kai Chiu, Stephen J. Pennycook, Ziqiang Wang and Hong-Jun Gao

Axial Higgs mode detected by quantum pathway interference in RTe3 pp. 896-901

Yiping Wang, Ioannis Petrides, Grant McNamara, Md Mofazzel Hosen, Shiming Lei, Yueh-Chun Wu, James L. Hart, Hongyan Lv, Jun Yan, Di Xiao, Judy J. Cha, Prineha Narang, Leslie M. Schoop and Kenneth S. Burch

Chiral molecular intercalation superlattices pp. 902-908

Qi Qian, Huaying Ren, Jingyuan Zhou, Zhong Wan, Jingxuan Zhou, Xingxu Yan, Jin Cai, Peiqi Wang, Bailing Li, Zdenek Sofer, Bo Li, Xidong Duan, Xiaoqing Pan, Yu Huang and Xiangfeng Duan

Hypocrystalline ceramic aerogels for thermal insulation at extreme conditions pp. 909-916

Jingran Guo, Shubin Fu, Yuanpeng Deng, Xiang Xu, Shujin Laima, Dizhou Liu, Pengyu Zhang, Jian Zhou, Han Zhao, Hongxuan Yu, Shixuan Dang, Jianing Zhang, Yingde Zhao, Hui Li and Xiangfeng Duan

Synthesis and target annotation of the alkaloid GB18 pp. 917-921

Stone Woo and Ryan A. Shenvi

Intermittent lab earthquakes in dynamically weakening fault gouge pp. 922-929

V. Rubino, N. Lapusta and A. J. Rosakis

Breakage of cytoplasmic chromosomes by pathological DNA base excision repair pp. 930-936

Shangming Tang, Ema Stokasimov, Yuxiang Cui and David Pellman

A preoptic neuronal population controls fever and appetite during sickness pp. 937-944

Jessica A. Osterhout, Vikrant Kapoor, Stephen W. Eichhorn, Eric Vaughn, Jeffrey D. Moore, Ding Liu, Dean Lee, Laura A. DeNardo, Liqun Luo, Xiaowei Zhuang and Catherine Dulac

Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4 pp. 945-952

Laura Campisi, Shahab Chizari, Jessica S. Y. Ho, Anastasia Gromova, Frederick J. Arnold, Lorena Mosca, Xueyan Mei, Yesai Fstkchyan, Denis Torre, Cindy Beharry, Marta Garcia-Forn, Miguel Jiménez-Alcázar, Vladislav A. Korobeynikov, Jack Prazich, Zahi A. Fayad, Marcus M. Seldin, Silvia Rubeis, Craig L. Bennett, Lyle W. Ostrow, Christian Lunetta, Massimo Squatrito, Minji Byun, Neil A. Shneider, Ning Jiang, Albert R. Spada and Ivan Marazzi

Peptidoglycan maturation controls outer membrane protein assembly pp. 953-959

Gideon Mamou, Federico Corona, Ruth Cohen-Khait, Nicholas G. Housden, Vivian Yeung, Dawei Sun, Pooja Sridhar, Manuel Pazos, Timothy J. Knowles, Colin Kleanthous and Waldemar Vollmer

Caspase-7 activates ASM to repair gasdermin and perforin pores pp. 960-967

Kengo Nozaki, Vivien I. Maltez, Manira Rayamajhi, Alan L. Tubbs, Joseph E. Mitchell, Carolyn A. Lacey, Carissa K. Harvest, Lupeng Li, William T. Nash, Heather N. Larson, Benjamin D. McGlaughon, Nathaniel J. Moorman, Michael G. Brown, Jason K. Whitmire and Edward A. Miao

ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids pp. 968-975

Rucha Patel, Anna Santoro, Peter Hofer, Dan Tan, Monika Oberer, Andrew T. Nelson, Srihari Konduri, Dionicio Siegel, Rudolf Zechner, Alan Saghatelian and Barbara B. Kahn

A pan-cancer compendium of chromosomal instability pp. 976-983

Ruben M. Drews, Barbara Hernando, Maxime Tarabichi, Kerstin Haase, Tom Lesluyes, Philip S. Smith, Lena Morrill Gavarró, Dominique-Laurent Couturier, Lydia Liu, Michael Schneider, James D. Brenton, Peter Van Loo, Geoff Macintyre and Florian Markowetz

Signatures of copy number alterations in human cancer pp. 984-991

Christopher D. Steele, Ammal Abbasi, S. M. Ashiqul Islam, Amy L. Bowes, Azhar Khandekar, Kerstin Haase, Shadi Hames-Fathi, Dolapo Ajayi, Annelien Verfaillie, Pawan Dhami, Alex McLatchie, Matt Lechner, Nicholas Light, Adam Shlien, David Malkin, Andrew Feber, Paula Proszek, Tom Lesluyes, Fredrik Mertens, Adrienne M. Flanagan, Maxime Tarabichi, Peter Loo, Ludmil B. Alexandrov and Nischalan Pillay

A vaccine targeting resistant tumours by dual T cell plus NK cell attack pp. 992-998

Soumya Badrinath, Maxence O. Dellacherie, Aileen Li, Shiwei Zheng, Xixi Zhang, Miguel Sobral, Jason W. Pyrdol, Kathryn L. Smith, Yuheng Lu, Sabrina Haag, Hamza Ijaz, Fawn Connor-Stroud, Tsuneyasu Kaisho, Glenn Dranoff, Guo-Cheng Yuan, David J. Mooney and Kai W. Wucherpfennig

The renal lineage factor PAX8 controls oncogenic signalling in kidney cancer pp. 999-1006

Saroor A. Patel, Shoko Hirosue, Paulo Rodrigues, Erika Vojtasova, Emma K. Richardson, Jianfeng Ge, Saiful E. Syafruddin, Alyson Speed, Evangelia K. Papachristou, David Baker, David Clarke, Stephenie Purvis, Ludovic Wesolowski, Anna Dyas, Leticia Castillon, Veronica Caraffini, Dóra Bihary, Cissy Yong, David J. Harrison, Grant D. Stewart, Mitchell J. Machiela, Mark P. Purdue, Stephen J. Chanock, Anne Y. Warren, Shamith A. Samarajiwa, Jason S. Carroll and Sakari Vanharanta

Mechanism of replication origin melting nucleated by CMG helicase assembly pp. 1007-1014

Jacob S. Lewis, Marta H. Gross, Joana Sousa, Sarah S. Henrikus, Julia F. Greiwe, Andrea Nans, John F. X. Diffley and Alessandro Costa

Structural basis of sodium-dependent bile salt uptake into the liver pp. 1015-1020

Kapil Goutam, Francesco S. Ielasi, Els Pardon, Jan Steyaert and Nicolas Reyes

Structure of the bile acid transporter and HBV receptor NTCP pp. 1021-1026

Jinta Asami, Kanako Terakado Kimura, Yoko Fujita-Fujiharu, Hanako Ishida, Zhikuan Zhang, Yayoi Nomura, Kehong Liu, Tomoko Uemura, Yumi Sato, Masatsugu Ono, Masaki Yamamoto, Takeshi Noda, Hideki Shigematsu, David Drew, So Iwata, Toshiyuki Shimizu, Norimichi Nomura and Umeharu Ohto

Structural insights into the HBV receptor and bile acid transporter NTCP pp. 1027-1031

Jae-Hyun Park, Masashi Iwamoto, Ji-Hye Yun, Tomomi Uchikubo-Kamo, Donghwan Son, Zeyu Jin, Hisashi Yoshida, Mio Ohki, Naito Ishimoto, Kenji Mizutani, Mizuki Oshima, Masamichi Muramatsu, Takaji Wakita, Mikako Shirouzu, Kehong Liu, Tomoko Uemura, Norimichi Nomura, So Iwata, Koichi Watashi, Jeremy R. H. Tame, Tomohiro Nishizawa, Weontae Lee and Sam-Yong Park

Swiss funder unveils new CV format to make grant evaluation fairer pp. 1033-1034

Dalmeet Singh Chawla

My work digging up the shelters of our ancestors pp. 1035-1035

Nic Fleming

How to make spatial maps of gene activity — down to the cellular level pp. 1036-1038

Michael Eisenstein

Plumbing the depths of Costa Rica’s volcanoes pp. 1040-1040

Jack Leeming

2022, volume 606, articles 7915

The science of smell steps into the spotlight pp. S1-S1

Richard Hodson

Unpicking the link between smell and memories pp. S2-S4

Roxanne Khamsi

The science behind COVID’s assault on smell pp. S5-S6

Elie Dolgin

How to bring back the sense of smell pp. S7-S9

Sarah DeWeerdt

Landfalling hurricane track modes and decay pp. E7-E11

Kelvin T. F. Chan, Kailin Zhang, Yue Wu and Johnny C. L. Chan

The dogs learning to sniff out disease pp. S10-S11

Julianna Photopoulos

Reply to: Landfalling hurricane track modes and decay pp. E12-E15

Lin Li and Pinaki Chakraborty

Restoring smell with an electronic nose pp. S12-S13

Simon Makin

Olfactory receptors are not unique to the nose pp. S14-S17

Liam Drew

Author Correction: Defining the consequences of genetic variation on a proteome-wide scale pp. E16-E16

Joel M. Chick, Steven C. Munger, Petr Simecek, Edward L. Huttlin, Kwangbom Choi, Daniel M. Gatti, Narayanan Raghupathy, Karen L. Svenson, Gary A. Churchill and Steven P. Gygi

Publisher Correction: Virtual communication curbs creative idea generation pp. E17-E17

Melanie S. Brucks and Jonathan Levav

Publisher Correction: Genomic reconstruction of the SARS CoV-2 epidemic in England pp. E18-E18

Harald S. Vöhringer, Theo Sanderson, Matthew Sinnott, Nicola Maio, Thuy Nguyen, Richard Goater, Frank Schwach, Ian Harrison, Joel Hellewell, Cristina V. Ariani, Sonia Gonçalves, David K. Jackson, Ian Johnston, Alexander W. Jung, Callum Saint, John Sillitoe, Maria Suciu, Nick Goldman, Jasmina Panovska-Griffiths, Ewan Birney, Erik Volz, Sebastian Funk, Dominic Kwiatkowski, Meera Chand, Inigo Martincorena, Jeffrey C. Barrett and Moritz Gerstung

Sniffing out smell’s effects on human behaviour pp. S18-S20

Michael Eisenstein

I have funds to buy reagents, but not remedies pp. 625-625

Kondwani Jambo

COVID and smell loss: answers begin to emerge pp. 631-632

Michael Marshall

Max Planck’s cherished autonomy questioned following criticism of misconduct investigations pp. 632-633

Alison Abbott

Legendary bacterial evolution experiment enters new era pp. 634-635

Ewen Callaway

Ancient DNA traces origin of Black Death pp. 635-636

Ewen Callaway

African researchers lead campaign for equity in global collaborations pp. 636-636

Holly Else

New COVID drugs face delays as trials grow more difficult pp. 637-637

Saima May Sidik

How COVID has deepened inequality — in six stark graphics pp. 638-639

Saima May Sidik

These experiments could lift millions out of dire poverty pp. 640-642

Jeff Tollefson

Tackling inequality takes social reform pp. 643-644

Richard Wilkinson and Kate Pickett

Bernard Bigot (1950–2022) pp. 645-645

Eisuke Tada

Not all inequalities are alike pp. 646-649

Francisco Ferreira

Sustainable small-scale fisheries can help people and the planet pp. 650-652

Sheryl L. Hendriks

Could artificial intelligence hijack author contributions? pp. 653-653

Akira Akabayashi, Eisuke Nakazawa and Hiroyasu Ino

Nature-based solutions for global climate adaptation pp. 653-653

Loan Diep and Timon McPhearson

IPCC decolonization call — policymakers must listen pp. 653-653

Chandran Nair

Misinformation: broaden definition to curb its societal influence pp. 653-653

Cecilie Steenbuch Traberg

Exercise molecule burns away hunger pp. 655-656

Tahnbee Kim and Scott M. Sternson

Collisions hint that four neutrons form a transient isolated entity pp. 656-657

Lee G. Sobotka and Maria Piarulli

Mutations matter even if proteins stay the same pp. 657-659

Nathaniel Sharp

60 years of chemistry of the noble gases pp. 659-661

Felice Grandinetti

Crystalline order offers access to high speeds for organic transistors pp. 661-662

Julie Euvrard and Barry P. Rand

Two-dimensional materials prospects for non-volatile spintronic memories pp. 663-673

Hyunsoo Yang, Sergio O. Valenzuela, Mairbek Chshiev, Sébastien Couet, Bernard Dieny, Bruno Dlubak, Albert Fert, Kevin Garello, Matthieu Jamet, Dae-Eun Jeong, Kangho Lee, Taeyoung Lee, Marie-Blandine Martin, Gouri Sankar Kar, Pierre Sénéor, Hyeon-Jin Shin and Stephan Roche

Solar flare accelerates nearly all electrons in a large coronal volume pp. 674-677

Gregory D. Fleishman, Gelu M. Nita, Bin Chen, Sijie Yu and Dale E. Gary

Observation of a correlated free four-neutron system pp. 678-682

M. Duer, T. Aumann, R. Gernhäuser, V. Panin, S. Paschalis, D. M. Rossi, N. L. Achouri, D. Ahn, H. Baba, C. A. Bertulani, M. Böhmer, K. Boretzky, C. Caesar, N. Chiga, A. Corsi, D. Cortina-Gil, C. A. Douma, F. Dufter, Z. Elekes, J. Feng, B. Fernández-Domínguez, U. Forsberg, N. Fukuda, I. Gasparic, Z. Ge, J. M. Gheller, J. Gibelin, A. Gillibert, K. I. Hahn, Z. Halász, M. N. Harakeh, A. Hirayama, M. Holl, N. Inabe, T. Isobe, J. Kahlbow, N. Kalantar-Nayestanaki, D. Kim, S. Kim, T. Kobayashi, Y. Kondo, D. Körper, P. Koseoglou, Y. Kubota, I. Kuti, P. J. Li, C. Lehr, S. Lindberg, Y. Liu, F. M. Marqués, S. Masuoka, M. Matsumoto, J. Mayer, K. Miki, B. Monteagudo, T. Nakamura, T. Nilsson, A. Obertelli, N. A. Orr, H. Otsu, S. Y. Park, M. Parlog, P. M. Potlog, S. Reichert, A. Revel, A. T. Saito, M. Sasano, H. Scheit, F. Schindler, S. Shimoura, H. Simon, L. Stuhl, H. Suzuki, D. Symochko, H. Takeda, J. Tanaka, Y. Togano, T. Tomai, H. T. Törnqvist, J. Tscheuschner, T. Uesaka, V. Wagner, H. Yamada, B. Yang, L. Yang, Z. H. Yang, M. Yasuda, K. Yoneda, L. Zanetti, J. Zenihiro and M. V. Zhukov

Continuous Bose–Einstein condensation pp. 683-687

Chun-Chia Chen, Rodrigo González Escudero, Jiří Minář, Benjamin Pasquiou, Shayne Bennetts and Florian Schreck

Many-body theory of positron binding to polyatomic molecules pp. 688-693

Jaroslav Hofierka, Brian Cunningham, Charlie M. Rawlins, Charles H. Patterson and Dermot G. Green

Engineering topological states in atom-based semiconductor quantum dots pp. 694-699

M. Kiczynski, S. K. Gorman, H. Geng, M. B. Donnelly, Y. Chung, Y. He, J. G. Keizer and M. Y. Simmons

Organic bipolar transistors pp. 700-705

Shu-Jen Wang, Michael Sawatzki, Ghader Darbandy, Felix Talnack, Jörn Vahland, Marc Malfois, Alexander Kloes, Stefan Mannsfeld, Hans Kleemann and Karl Leo

Asymmetric pore windows in MOF membranes for natural gas valorization pp. 706-712

Sheng Zhou, Osama Shekhah, Adrian Ramírez, Pengbo Lyu, Edy Abou-Hamad, Jiangtao Jia, Jiantang Li, Prashant M. Bhatt, Zhiyuan Huang, Hao Jiang, Tian Jin, Guillaume Maurin, Jorge Gascon and Mohamed Eddaoudi

Hadean isotopic fractionation of xenon retained in deep silicates pp. 713-717

Igor Rzeplinski, Chrystèle Sanloup, Eric Gilabert and Denis Horlait

The source of the Black Death in fourteenth-century central Eurasia pp. 718-724

Maria A. Spyrou, Lyazzat Musralina, Guido A. Gnecchi Ruscone, Arthur Kocher, Pier-Giorgio Borbone, Valeri I. Khartanovich, Alexandra Buzhilova, Leyla Djansugurova, Kirsten I. Bos, Denise Kühnert, Wolfgang Haak, Philip Slavin and Johannes Krause

Synonymous mutations in representative yeast genes are mostly strongly non-neutral pp. 725-731

Xukang Shen, Siliang Song, Chuan Li and Jianzhi Zhang

Spatiotemporal dynamics of noradrenaline during learned behaviour pp. 732-738

Vincent Breton-Provencher, Gabrielle T. Drummond, Jiesi Feng, Yulong Li and Mriganka Sur

Molecularly defined circuits for cardiovascular and cardiopulmonary control pp. 739-746

Avin Veerakumar, Andrea R. Yung, Yin Liu and Mark A. Krasnow

Lifelong multilineage contribution by embryonic-born blood progenitors pp. 747-753

Sachin H. Patel, Constantina Christodoulou, Caleb Weinreb, Qi Yu, Edroaldo Lummertz da Rocha, Brian J. Pepe-Mooney, Sarah Bowling, Li Li, Fernando G. Osorio, George Q. Daley and Fernando D. Camargo

Discovery of bioactive microbial gene products in inflammatory bowel disease pp. 754-760

Yancong Zhang, Amrisha Bhosle, Sena Bae, Lauren J. McIver, Gleb Pishchany, Emma K. Accorsi, Kelsey N. Thompson, Cesar Arze, Ya Wang, Ayshwarya Subramanian, Sean M. Kearney, April Pawluk, Damian R. Plichta, Ali Rahnavard, Afrah Shafquat, Ramnik J. Xavier, Hera Vlamakis, Wendy S. Garrett, Andy Krueger, Curtis Huttenhower and Eric A. Franzosa

The role of NSP6 in the biogenesis of the SARS-CoV-2 replication organelle pp. 761-768

Simona Ricciardi, Andrea Maria Guarino, Laura Giaquinto, Elena V. Polishchuk, Michele Santoro, Giuseppe Di Tullio, Cathal Wilson, Francesco Panariello, Vinicius C. Soares, Suelen S. G. Dias, Julia C. Santos, Thiago M. L. Souza, Giovanna Fusco, Maurizio Viscardi, Sergio Brandi, Patrícia T. Bozza, Roman S. Polishchuk, Rossella Venditti and Maria Antonietta De Matteis

Pregnancy enables antibody protection against intracellular infection pp. 769-775

John J. Erickson, Stephanie Archer-Hartmann, Alexander E. Yarawsky, Jeanette L. C. Miller, Stephanie Seveau, Tzu-Yu Shao, Ashley L. Severance, Hilary Miller-Handley, Yuehong Wu, Giang Pham, Brian R. Wasik, Colin R. Parrish, Yueh-Chiang Hu, Joseph T. Y. Lau, Parastoo Azadi, Andrew B. Herr and Sing Sing Way

Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes pp. 776-784

Sophia Maschalidi, Parul Mehrotra, Burcu N. Keçeli, Hannah K. L. Cleene, Kim Lecomte, Renée Cruyssen, Pauline Janssen, Jonathan Pinney, Geert Loo, Dirk Elewaut, Ann Massie, Esther Hoste and Kodi S. Ravichandran

An exercise-inducible metabolite that suppresses feeding and obesity pp. 785-790

Veronica L. Li, Yang He, Kévin Contrepois, Hailan Liu, Joon T. Kim, Amanda L. Wiggenhorn, Julia T. Tanzo, Alan Sheng-Hwa Tung, Xuchao Lyu, Peter-James H. Zushin, Robert S. Jansen, Basil Michael, Kang Yong Loh, Andrew C. Yang, Christian S. Carl, Christian T. Voldstedlund, Wei Wei, Stephanie M. Terrell, Benjamin C. Moeller, Rick M. Arthur, Gareth A. Wallis, Koen Wetering, Andreas Stahl, Bente Kiens, Erik A. Richter, Steven M. Banik, Michael P. Snyder, Yong Xu and Jonathan Z. Long

Androgen receptor activity in T cells limits checkpoint blockade efficacy pp. 791-796

Xiangnan Guan, Fanny Polesso, Chaojie Wang, Archana Sehrawat, Reed M. Hawkins, Susan E. Murray, George V. Thomas, Breanna Caruso, Reid F. Thompson, Mary A. Wood, Christina Hipfinger, Scott A. Hammond, Julie N. Graff, Zheng Xia and Amy E. Moran

Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy pp. 797-803

Christopher P. Vellano, Michael G. White, Miles C. Andrews, Manoj Chelvanambi, Russell G. Witt, Joseph R. Daniele, Mark Titus, Jennifer L. McQuade, Fabio Conforti, Elizabeth M. Burton, Matthew J. Lastrapes, Gabriel Ologun, Alexandria P. Cogdill, Golnaz Morad, Peter Prieto, Alexander J. Lazar, Yanshuo Chu, Guangchun Han, M. A. Wadud Khan, Beth Helmink, Michael A. Davies, Rodabe N. Amaria, Jeffrey J. Kovacs, Scott E. Woodman, Sapna Patel, Patrick Hwu, Michael Peoples, Jeffrey E. Lee, Zachary A. Cooper, Haifeng Zhu, Guang Gao, Hiya Banerjee, Mike Lau, Jeffrey E. Gershenwald, Anthony Lucci, Emily Z. Keung, Merrick I. Ross, Laura Pala, Eleonora Pagan, Rossana Lazcano Segura, Qian Liu, Mikayla S. Borthwick, Eric Lau, Melinda S. Yates, Shannon N. Westin, Khalida Wani, Michael T. Tetzlaff, Lauren E. Haydu, Mikhila Mahendra, XiaoYan Ma, Christopher Logothetis, Zachary Kulstad, Sarah Johnson, Courtney W. Hudgens, Ningping Feng, Lorenzo Federico, Georgina V. Long, P. Andrew Futreal, Swathi Arur, Hussein A. Tawbi, Amy E. Moran, Linghua Wang, Timothy P. Heffernan, Joseph R. Marszalek and Jennifer A. Wargo

Mitochondrial base editor induces substantial nuclear off-target mutations pp. 804-811

Zhixin Lei, Haowei Meng, Lulu Liu, Huanan Zhao, Xichen Rao, Yongchang Yan, Hao Wu, Min Liu, Aibin He and Chengqi Yi

Cohesin-mediated loop anchors confine the locations of human replication origins pp. 812-819

Daniel J. Emerson, Peiyao A. Zhao, Ashley L. Cook, R. Jordan Barnett, Kyle N. Klein, Dalila Saulebekova, Chunmin Ge, Linda Zhou, Zoltan Simandi, Miriam K. Minsk, Katelyn R. Titus, Weitao Wang, Wanfeng Gong, Di Zhang, Liyan Yang, Sergey V. Venev, Johan H. Gibcus, Hongbo Yang, Takayo Sasaki, Masato T. Kanemaki, Feng Yue, Job Dekker, Chun-Long Chen, David M. Gilbert and Jennifer E. Phillips-Cremins

Structural basis of GABA reuptake inhibition pp. 820-826

Zenia Motiwala, Nanda Gowtham Aduri, Hamidreza Shaye, Gye Won Han, Jordy Homing Lam, Vsevolod Katritch, Vadim Cherezov and Cornelius Gati

The rise of inequality research: can spanning disciplines help tackle injustice? pp. 827-829

Virginia Gewin

Shark researcher attacks lack of diversity in marine science pp. 832-832

Virginia Gewin

2022, volume 606, articles 7914

Author Correction: Assembly of the basal mantle structure beneath Africa pp. E4-E4

Nicolas Flament, Ömer F. Bodur, Simon E. Williams and Andrew S. Merdith

Author Correction: Fundamental immune–oncogenicity trade-offs define driver mutation fitness pp. E5-E5

David Hoyos, Roberta Zappasodi, Isabell Schulze, Zachary Sethna, Kelvin César Andrade, Dean F. Bajorin, Chaitanya Bandlamudi, Margaret K. Callahan, Samuel A. Funt, Sine R. Hadrup, Jeppe S. Holm, Jonathan E. Rosenberg, Sohrab P. Shah, Ignacio Vázquez-García, Britta Weigelt, Michelle Wu, Dmitriy Zamarin, Laura F. Campitelli, Edward J. Osborne, Mark Klinger, Harlan S. Robins, Payal P. Khincha, Sharon A. Savage, Vinod P. Balachandran, Jedd D. Wolchok, Matthew D. Hellmann, Taha Merghoub, Arnold J. Levine, Marta Łuksza and Benjamin D. Greenbaum

Publisher Correction: A stable hippocampal code in freely flying bats pp. E6-E6

William A. Liberti, Tobias A. Schmid, Angelo Forli, Madeleine Snyder and Michael M. Yartsev

The human microbiome: there is much left to do pp. 435-435

Ruth Ley

NASA’s Perseverance rover begins key search for life on Mars pp. 441-442

Alexandra Witze

Gene therapy’s comeback: how scientists are trying to make it safer pp. 443-444

Heidi Ledford

Monkeypox vaccination begins — can the global outbreaks be contained? pp. 444-445

Max Kozlov

Why call it BA.2.12.1? A guide to the tangled Omicron family pp. 446-447

Amy Maxmen

Indigenous knowledge reveals history of fire-prone California forest pp. 447-447

Jude Coleman

Why chemists can’t quit palladium pp. 448-451

Ariana Remmel

How months-long COVID infections could seed dangerous new variants pp. 452-455

Ewen Callaway

Learn from COVID: Gates’s pandemic prescription pp. 457-458

Matthew M. Kavanagh

Female dominance, and coding for kids: Books in brief pp. 458-458

Andrew Robinson

Benjamin Mottelson (1926–2022) pp. 459-459

Helge Kragh

Fuel crisis: slash demand in three sectors to protect economies and climate pp. 460-462

Felix Creutzig

Survey data must be top-notch to tackle societal crises pp. 463-463

Ulf Liebe

Fleeing Russian researchers seek Western support pp. 463-463

Sergei M. Mirkin, Alexander Vilenkin and Polina Deletic

Mars: do we still need astronauts? pp. 463-463

Donald Goldsmith and Martin Rees

Industry versus academia — a mid-life career switch pp. 463-463

Victoria Sherwood

25 years of valuing ecosystems in decision-making pp. 465-466

Gretchen C. Daily and Mary Ruckelshaus

Tiny isotopic difference tests standard model of particle physics pp. 467-468

Gerald Gwinner and Roshani Silwal

The first complete human genome pp. 468-469

John T. Lovell and Jane Grimwood

Molecular soccer balls connected to make a 2D material pp. 470-471

J. Michael Gottfried

Give physicians’ views to improve COVID vaccine uptake pp. 471-472

Nina Mažar

Potato genomes pave the way to crop improvement pp. 472-473

Juanita Gutiérrez-Valencia and Tanja Slotte

A population of ultraviolet-dim protoclusters detected in absorption pp. 475-478

Andrew B. Newman, Gwen C. Rudie, Guillermo A. Blanc, Mahdi Qezlou, Simeon Bird, Daniel D. Kelson, Victoria Pérez, Enrico Congiu, Brian C. Lemaux, Alan Dressler and John S. Mulchaey

Measurement of the bound-electron g-factor difference in coupled ions pp. 479-483

Tim Sailer, Vincent Debierre, Zoltán Harman, Fabian Heiße, Charlotte König, Jonathan Morgner, Bingsheng Tu, Andrey V. Volotka, Christoph H. Keitel, Klaus Blaum and Sven Sturm

Realizing the symmetry-protected Haldane phase in Fermi–Hubbard ladders pp. 484-488

Pimonpan Sompet, Sarah Hirthe, Dominik Bourgund, Thomas Chalopin, Julian Bibo, Joannis Koepsell, Petar Bojović, Ruben Verresen, Frank Pollmann, Guillaume Salomon, Christian Gross, Timon A. Hilker and Immanuel Bloch

Superconducting-qubit readout via low-backaction electro-optic transduction pp. 489-493

R. D. Delaney, M. D. Urmey, S. Mittal, B. M. Brubaker, J. M. Kindem, P. S. Burns, C. A. Regal and K. W. Lehnert

Evidence for unconventional superconductivity in twisted trilayer graphene pp. 494-500

Hyunjin Kim, Youngjoon Choi, Cyprian Lewandowski, Alex Thomson, Yiran Zhang, Robert Polski, Kenji Watanabe, Takashi Taniguchi, Jason Alicea and Stevan Nadj-Perge

An on-chip photonic deep neural network for image classification pp. 501-506

Farshid Ashtiani, Alexander J. Geers and Firooz Aflatouni

Synthesis of a monolayer fullerene network pp. 507-510

Lingxiang Hou, Xueping Cui, Bo Guan, Shaozhi Wang, Ruian Li, Yunqi Liu, Daoben Zhu and Jian Zheng

A solid-state electrolysis process for upcycling aluminium scrap pp. 511-515

Xin Lu, Zhengyang Zhang, Takehito Hiraki, Osamu Takeda, Hongmin Zhu, Kazuyo Matsubae and Tetsuya Nagasaka

Topography of mountain belts controlled by rheology and surface processes pp. 516-521

Sebastian G. Wolf, Ritske S. Huismans, Jean Braun and Xiaoping Yuan

Fossil biomolecules reveal an avian metabolism in the ancestral dinosaur pp. 522-526

Jasmina Wiemann, Iris Menéndez, Jason M. Crawford, Matteo Fabbri, Jacques A. Gauthier, Pincelli M. Hull, Mark A. Norell and Derek E. G. Briggs

Graph pangenome captures missing heritability and empowers tomato breeding pp. 527-534

Yao Zhou, Zhiyang Zhang, Zhigui Bao, Hongbo Li, Yaqing Lyu, Yanjun Zan, Yaoyao Wu, Lin Cheng, Yuhan Fang, Kun Wu, Jinzhe Zhang, Hongjun Lyu, Tao Lin, Qiang Gao, Surya Saha, Lukas Mueller, Zhangjun Fei, Thomas Städler, Shizhong Xu, Zhiwu Zhang, Doug Speed and Sanwen Huang

Genome evolution and diversity of wild and cultivated potatoes pp. 535-541

Dié Tang, Yuxin Jia, Jinzhe Zhang, Hongbo Li, Lin Cheng, Pei Wang, Zhigui Bao, Zhihong Liu, Shuangshuang Feng, Xijian Zhu, Dawei Li, Guangtao Zhu, Hongru Wang, Yao Zhou, Yongfeng Zhou, Glenn J. Bryan, C. Robin Buell, Chunzhi Zhang and Sanwen Huang

Communicating doctors’ consensus persistently increases COVID-19 vaccinations pp. 542-549

Vojtěch Bartoš, Michal Bauer, Jana Cahlíková and Julie Chytilová

Olfactory sensory experience regulates gliomagenesis via neuronal IGF1 pp. 550-556

Pengxiang Chen, Wei Wang, Rui Liu, Jiahui Lyu, Lei Zhang, Baizhou Li, Biying Qiu, Anhao Tian, Wenhong Jiang, Honggang Ying, Rui Jing, Qianqian Wang, Keqing Zhu, Ruiliang Bai, Linghui Zeng, Shumin Duan and Chong Liu

Divergent transcriptional regulation of astrocyte reactivity across disorders pp. 557-564

Joshua E. Burda, Timothy M. O’Shea, Yan Ao, Keshav B. Suresh, Shinong Wang, Alexander M. Bernstein, Ashu Chandra, Sandeep Deverasetty, Riki Kawaguchi, Jae H. Kim, Sarah McCallum, Alexandra Rogers, Shalaka Wahane and Michael V. Sofroniew

An oxygen-sensing mechanism for angiosperm adaptation to altitude pp. 565-569

Mohamad Abbas, Gunjan Sharma, Charlene Dambire, Julietta Marquez, Carlos Alonso-Blanco, Karina Proaño and Michael J. Holdsworth

Generation of specialized blood vessels via lymphatic transdifferentiation pp. 570-575

Rudra N. Das, Yaara Tevet, Stav Safriel, Yanchao Han, Noga Moshe, Giuseppina Lambiase, Ivan Bassi, Julian Nicenboim, Matthias Brückner, Dana Hirsch, Raya Eilam-Altstadter, Wiebke Herzog, Roi Avraham, Kenneth D. Poss and Karina Yaniv

FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation pp. 576-584

Caroline Junqueira, Ângela Crespo, Shahin Ranjbar, Luna B. Lacerda, Mercedes Lewandrowski, Jacob Ingber, Blair Parry, Sagi Ravid, Sarah Clark, Marie Rose Schrimpf, Felicia Ho, Caroline Beakes, Justin Margolin, Nicole Russell, Kyle Kays, Julie Boucau, Upasana Adhikari, Setu M. Vora, Valerie Leger, Lee Gehrke, Lauren A. Henderson, Erin Janssen, Douglas Kwon, Chris Sander, Jonathan Abraham, Marcia B. Goldberg, Hao Wu, Gautam Mehta, Steven Bell, Anne E. Goldfeld, Michael R. Filbin and Judy Lieberman

Inflammasome activation in infected macrophages drives COVID-19 pathology pp. 585-593

Esen Sefik, Rihao Qu, Caroline Junqueira, Eleanna Kaffe, Haris Mirza, Jun Zhao, J. Richard Brewer, Ailin Han, Holly R. Steach, Benjamin Israelow, Holly N. Blackburn, Sofia E. Velazquez, Y. Grace Chen, Stephanie Halene, Akiko Iwasaki, Eric Meffre, Michel Nussenzweig, Judy Lieberman, Craig B. Wilen, Yuval Kluger and Richard A. Flavell

ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis pp. 594-602

Ting Zhang, Chaoran Yin, Aleksandr Fedorov, Liangjun Qiao, Hongliang Bao, Nazar Beknazarov, Shiyu Wang, Avishekh Gautam, Riley M. Williams, Jeremy Chase Crawford, Suraj Peri, Vasily Studitsky, Amer A. Beg, Paul G. Thomas, Carl Walkley, Yan Xu, Maria Poptsova, Alan Herbert and Siddharth Balachandran

Mechanism of mitoribosomal small subunit biogenesis and preinitiation pp. 603-608

Yuzuru Itoh, Anas Khawaja, Ivan Laptev, Miriam Cipullo, Ilian Atanassov, Petr Sergiev, Joanna Rorbach and Alexey Amunts

Peer-to-peer careers advice for research managers pp. 609-611

Nikki Forrester

Cloud labs: where robots do the research pp. 612-613

Carrie Arnold

Sniffing out forest fungi pp. 616-616

Nic Fleming

2022, volume 606, articles 7913

Limitations of gamete sequencing for crossover analysis pp. E1-E3

Carl Veller, Shunxin Wang, Denise Zickler, Liangran Zhang and Nancy Kleckner

Science must overcome its racist legacy: Nature’s guest editors speak pp. 225-227

Melissa Nobles, Chad Womack, Ambroise Wonkam and Elizabeth Wathuti

To boost South Korea’s basic science, look to values, not just budgets pp. 229-229

So Young Kim

The number of researchers with dual US–China affiliations is falling pp. 235-236

Richard Van Noorden

‘Unsustainable’: how satellite swarms pose a rising threat to astronomy pp. 236-237

Alexandra Witze

Monkeypox outbreaks: 4 key questions researchers have pp. 238-239

Max Kozlov

How the giraffe got its neck: ‘unicorn’ fossil could shed light on puzzle pp. 239-239

Nicola Jones

Mathematics prizes have a gender problem — can it be fixed? pp. 240-241

Davide Castelvecchi

COVID death tolls: scientists acknowledge errors in WHO estimates pp. 242-244

Richard Van Noorden

Floating solar power could help fight climate change — let’s get it right pp. 246-249

Rafael M. Almeida, Rafael Schmitt, Steven M. Grodsky, Alexander S. Flecker, Carla P. Gomes, Lu Zhao, Haohui Liu, Nathan Barros, Rafael Kelman and Peter B. McIntyre

Conflict’s impact raises costs for Arctic shipping and the climate pp. 250-250

Michael A. Goldstein, Amanda H. Lynch and Charles H. Norchi

Climate alone won’t define future worlds pp. 250-250

Mike Hulme

Complement CVs with curated portfolios pp. 250-250

Sylvia J. Hysong

Funding: end ‘publish or perish’ for postdocs pp. 250-250

Thomas Lemberger, Bernd Pulverer, Kelly Sheehan-Rooney and Fiona M. Watt

How wingless salamanders fly pp. 251-252

David Lentink

Nanoscale map shows how interfaces impede vibrations pp. 252-253

Fredrik S. Hage

Large-scale early urban settlements in Amazonia pp. 254-255

Christopher T. Fisher

Blood’s life history traced through genomic scars pp. 255-256

Aswin Sekar and Benjamin L. Ebert

A chromosome predisposed for sex pp. 257-258

Yuying Lin and Judith E. Mank

Diverse data tighten constraints for neutron stars pp. 258-259

Jorge Noronha

X-ray astronomy comes of age pp. 261-271

Belinda J. Wilkes, Wallace Tucker, Norbert Schartel and Maria Santos-Lleo

Binarity of a protostar affects the evolution of the disk and planets pp. 272-275

Jes K. Jørgensen, Rajika L. Kuruwita, Daniel Harsono, Troels Haugbølle, Lars E. Kristensen and Edwin A. Bergin

Constraining neutron-star matter with microscopic and macroscopic collisions pp. 276-280

Sabrina Huth, Peter T. H. Pang, Ingo Tews, Tim Dietrich, Arnaud Fèvre, Achim Schwenk, Wolfgang Trautmann, Kshitij Agarwal, Mattia Bulla, Michael W. Coughlin and Chris Broeck

Observation of ultracold atomic bubbles in orbital microgravity pp. 281-286

R. A. Carollo, D. C. Aveline, B. Rhyno, S. Vishveshwara, C. Lannert, J. D. Murphree, E. R. Elliott, J. R. Williams, R. J. Thompson and N. Lundblad

Observation of Cooper pairs in a mesoscopic two-dimensional Fermi gas pp. 287-291

Marvin Holten, Luca Bayha, Keerthan Subramanian, Sandra Brandstetter, Carl Heintze, Philipp Lunt, Philipp M. Preiss and Selim Jochim

Nanoscale imaging of phonon dynamics by electron microscopy pp. 292-297

Chaitanya A. Gadre, Xingxu Yan, Qichen Song, Jie Li, Lei Gu, Huaixun Huyan, Toshihiro Aoki, Sheng-Wei Lee, Gang Chen, Ruqian Wu and Xiaoqing Pan

Electrically tunable quantum confinement of neutral excitons pp. 298-304

Deepankur Thureja, Atac Imamoglu, Tomasz Smoleński, Ivan Amelio, Alexander Popert, Thibault Chervy, Xiaobo Lu, Song Liu, Katayun Barmak, Kenji Watanabe, Takashi Taniguchi, David J. Norris, Martin Kroner and Puneet A. Murthy

Origin of structural degradation in Li-rich layered oxide cathode pp. 305-312

Tongchao Liu, Jiajie Liu, Luxi Li, Lei Yu, Jiecheng Diao, Tao Zhou, Shunning Li, Alvin Dai, Wenguang Zhao, Shenyang Xu, Yang Ren, Liguang Wang, Tianpin Wu, Rui Qi, Yinguo Xiao, Jiaxin Zheng, Wonsuk Cha, Ross Harder, Ian Robinson, Jianguo Wen, Jun Lu, Feng Pan and Khalil Amine

Ni-electrocatalytic Csp3–Csp3 doubly decarboxylative coupling pp. 313-318

Benxiang Zhang, Yang Gao, Yuta Hioki, Martins S. Oderinde, Jennifer X. Qiao, Kevin X. Rodriguez, Hai-Jun Zhang, Yu Kawamata and Phil S. Baran

Instantaneous tracking of earthquake growth with elastogravity signals pp. 319-324

Andrea Licciardi, Quentin Bletery, Bertrand Rouet-Leduc, Jean-Paul Ampuero and Kévin Juhel

Lidar reveals pre-Hispanic low-density urbanism in the Bolivian Amazon pp. 325-328

Heiko Prümers, Carla Jaimes Betancourt, José Iriarte, Mark Robinson and Martin Schaich

Island-specific evolution of a sex-primed autosome in a sexual planarian pp. 329-334

Longhua Guo, Joshua S. Bloom, Daniel Dols-Serrate, James Boocock, Eyal Ben-David, Olga T. Schubert, Kaiya Kozuma, Katarina Ho, Emily Warda, Clarice Chui, Yubao Wei, Daniel Leighton, Tzitziki Lemus Vergara, Marta Riutort, Alejandro Sánchez Alvarado and Leonid Kruglyak

The longitudinal dynamics and natural history of clonal haematopoiesis pp. 335-342

Margarete A. Fabre, José Guilherme Almeida, Edoardo Fiorillo, Emily Mitchell, Aristi Damaskou, Justyna Rak, Valeria Orrù, Michele Marongiu, Michael Spencer Chapman, M. S. Vijayabaskar, Joanna Baxter, Claire Hardy, Federico Abascal, Nicholas Williams, Jyoti Nangalia, Iñigo Martincorena, Peter J. Campbell, Eoin F. McKinney, Francesco Cucca, Moritz Gerstung and George S. Vassiliou

Clonal dynamics of haematopoiesis across the human lifespan pp. 343-350

Emily Mitchell, Michael Spencer Chapman, Nicholas Williams, Kevin J. Dawson, Nicole Mende, Emily F. Calderbank, Hyunchul Jung, Thomas Mitchell, Tim H. H. Coorens, David H. Spencer, Heather Machado, Henry Lee-Six, Megan Davies, Daniel Hayler, Margarete A. Fabre, Krishnaa Mahbubani, Federico Abascal, Alex Cagan, George S. Vassiliou, Joanna Baxter, Inigo Martincorena, Michael R. Stratton, David G. Kent, Krishna Chatterjee, Kourosh Saeb Parsy, Anthony R. Green, Jyoti Nangalia, Elisa Laurenti and Peter J. Campbell

Revival of light signalling in the postmortem mouse and human retina pp. 351-357

Fatima Abbas, Silke Becker, Bryan W. Jones, Ludovic S. Mure, Satchidananda Panda, Anne Hanneken and Frans Vinberg

ABO genotype alters the gut microbiota by regulating GalNAc levels in pigs pp. 358-367

Hui Yang, Jinyuan Wu, Xiaochang Huang, Yunyan Zhou, Yifeng Zhang, Min Liu, Qin Liu, Shanlin Ke, Maozhang He, Hao Fu, Shaoming Fang, Xinwei Xiong, Hui Jiang, Zhe Chen, Zhongzi Wu, Huanfa Gong, Xinkai Tong, Yizhong Huang, Junwu Ma, Jun Gao, Carole Charlier, Wouter Coppieters, Lev Shagam, Zhiyan Zhang, Huashui Ai, Bin Yang, Michel Georges, Congying Chen and Lusheng Huang

Prolonged viral suppression with anti-HIV-1 antibody therapy pp. 368-374

Christian Gaebler, Lilian Nogueira, Elina Stoffel, Thiago Y. Oliveira, Gaëlle Breton, Katrina G. Millard, Martina Turroja, Allison Butler, Victor Ramos, Michael S. Seaman, Jacqueline D. Reeves, Christos J. Petroupoulos, Irina Shimeliovich, Anna Gazumyan, Caroline S. Jiang, Nikolaus Jilg, Johannes F. Scheid, Rajesh Gandhi, Bruce D. Walker, Michael C. Sneller, Anthony Fauci, Tae-Wook Chun, Marina Caskey and Michel C. Nussenzweig

Combination anti-HIV antibodies provide sustained virological suppression pp. 375-381

Michael C. Sneller, Jana Blazkova, J. Shawn Justement, Victoria Shi, Brooke D. Kennedy, Kathleen Gittens, Jekaterina Tolstenko, Genevieve McCormack, Emily J. Whitehead, Rachel F. Schneck, Michael A. Proschan, Erika Benko, Colin Kovacs, Cihan Oguz, Michael S. Seaman, Marina Caskey, Michel C. Nussenzweig, Anthony S. Fauci, Susan Moir and Tae-Wook Chun

Defining mitochondrial protein functions through deep multiomic profiling pp. 382-388

Jarred W. Rensvold, Evgenia Shishkova, Yuriy Sverchkov, Ian J. Miller, Arda Cetinkaya, Angela Pyle, Mateusz Manicki, Dain R. Brademan, Yasemin Alanay, Julian Raiman, Adam Jochem, Paul D. Hutchins, Sean R. Peters, Vanessa Linke, Katherine A. Overmyer, Austin Z. Salome, Alexander S. Hebert, Catherine E. Vincent, Nicholas W. Kwiecien, Matthew J. P. Rush, Michael S. Westphall, Mark Craven, Nurten A. Akarsu, Robert W. Taylor, Joshua J. Coon and David J. Pagliarini

Neoantigen quality predicts immunoediting in survivors of pancreatic cancer pp. 389-395

Marta Łuksza, Zachary M. Sethna, Luis A. Rojas, Jayon Lihm, Barbara Bravi, Yuval Elhanati, Kevin Soares, Masataka Amisaki, Anton Dobrin, David Hoyos, Pablo Guasp, Abderezak Zebboudj, Rebecca Yu, Adrienne Kaya Chandra, Theresa Waters, Zagaa Odgerel, Joanne Leung, Rajya Kappagantula, Alvin Makohon-Moore, Amber Johns, Anthony Gill, Mathieu Gigoux, Jedd Wolchok, Taha Merghoub, Michel Sadelain, Erin Patterson, Remi Monasson, Thierry Mora, Aleksandra M. Walczak, Simona Cocco, Christine Iacobuzio-Donahue, Benjamin D. Greenbaum and Vinod P. Balachandran

Stromal changes in the aged lung induce an emergence from melanoma dormancy pp. 396-405

Mitchell E. Fane, Yash Chhabra, Gretchen M. Alicea, Devon A. Maranto, Stephen M. Douglass, Marie R. Webster, Vito W. Rebecca, Gloria E. Marino, Filipe Almeida, Brett L. Ecker, Daniel J. Zabransky, Laura Hüser, Thomas Beer, Hsin-Yao Tang, Andrew Kossenkov, Meenhard Herlyn, David W. Speicher, Wei Xu, Xiaowei Xu, Elizabeth M. Jaffee, Julio A. Aguirre-Ghiso and Ashani T. Weeraratna

Differential cofactor dependencies define distinct types of human enhancers pp. 406-413

Christoph Neumayr, Vanja Haberle, Leonid Serebreni, Katharina Karner, Oliver Hendy, Ann Boija, Jonathan E. Henninger, Charles H. Li, Karel Stejskal, Gen Lin, Katharina Bergauer, Michaela Pagani, Martina Rath, Karl Mechtler, Cosmas D. Arnold and Alexander Stark

Discovery of non-squalene triterpenes pp. 414-419

Hui Tao, Lukas Lauterbach, Guangkai Bian, Rong Chen, Anwei Hou, Takahiro Mori, Shu Cheng, Ben Hu, Li Lu, Xin Mu, Min Li, Naruhiko Adachi, Masato Kawasaki, Toshio Moriya, Toshiya Senda, Xinghuan Wang, Zixin Deng, Ikuro Abe, Jeroen S. Dickschat and Tiangang Liu

Retraction Note: A constraint on historic growth in global photosynthesis due to increasing CO2 pp. 420-420

T. F. Keenan, X. Luo, M. G. Kauwe, B. E. Medlyn, I. C. Prentice, B. D. Stocker, N. G. Smith, C. Terrer, H. Wang, Y. Zhang and S. Zhou

The sting of sizeism in the scientific workplace pp. 421-423

Carrie Arnold

Pico pioneer: building tiny satellites for the Internet of Things pp. 426-426

Virginia Gewin

2022, volume 606, articles 7912

Fix the process that led to Alzheimer’s drug fiasco pp. 9-9

Jason Karlawish

Monkeypox goes global: why scientists are on alert pp. 15-16

Max Kozlov

‘Mind blowing’ ancient settlements uncovered in the Amazon pp. 16-17

Freda Kreier

Why unprecedented bird flu outbreaks sweeping the world are concerning scientists pp. 18-19

Brittney J. Miller

COVID delays are frustrating the world’s plans to save biodiversity pp. 19-20

Smriti Mallapaty

Frustration builds over lengthy delay in revamping Mexico’s science law pp. 20-21

Emiliano Rodríguez Mega

Guardians of the brain: how a special immune system protects our grey matter pp. 22-24

Diana Kwon

Chronic pain — why science has scant succour for one in five people pp. 25-26

Julian Nowogrodzki

Animal power, and how to perpetuate wonder: Books in brief pp. 26-26

Andrew Robinson

A century of science boycotts pp. 27-29

Michael D. Gordin

Fifty years after UN environment summit, researchers renew call for action pp. 30-30

Maria Ivanova and Sharachchandra Lele

Loops simplify a set-up to boost quantum computational advantage pp. 31-32

Daniel Jost Brod

Nerve regrowth can be painful pp. 32-33

Suna L. Cranfill and Wenqin Luo

The 6G frequency switch that spares scientific services pp. 34-35

Janise McNair

Clues to the identity of the fossil fish Palaeospondylus pp. 35-37

Jorge Mondéjar Fernández and Philippe Janvier

Multilayer 2D insulator shows promise for post-silicon electronics pp. 37-38

Soo Ho Choi and Soo Min Kim

An immune molecule segregates memories in time pp. 38-39

Andrea Terceros and Priya Rajasethupathy

Strongly correlated electron–photon systems pp. 41-48

Jacqueline Bloch, Andrea Cavalleri, Victor Galitski, Mohammad Hafezi and Angel Rubio

The road to fully programmable protein catalysis pp. 49-58

Sarah L. Lovelock, Rebecca Crawshaw, Sophie Basler, Colin Levy, David Baker, Donald Hilvert and Anthony P. Green

Resolving the H i in damped Lyman α systems that power star formation pp. 59-63

Rongmon Bordoloi, John M. O’Meara, Keren Sharon, Jane R. Rigby, Jeff Cooke, Ahmed Shaban, Mateusz Matuszewski, Luca Rizzi, Greg Doppmann, D. Christopher Martin, Anna M. Moore, Patrick Morrissey and James D. Neill

Magneto-optical trapping and sub-Doppler cooling of a polyatomic molecule pp. 70-74

Nathaniel B. Vilas, Christian Hallas, Loïc Anderegg, Paige Robichaud, Andrew Winnicki, Debayan Mitra and John M. Doyle

Quantum computational advantage with a programmable photonic processor pp. 75-81

Lars S. Madsen, Fabian Laudenbach, Mohsen Falamarzi. Askarani, Fabien Rortais, Trevor Vincent, Jacob F. F. Bulmer, Filippo M. Miatto, Leonhard Neuhaus, Lukas G. Helt, Matthew J. Collins, Adriana E. Lita, Thomas Gerrits, Sae Woo Nam, Varun D. Vaidya, Matteo Menotti, Ish Dhand, Zachary Vernon, Nicolás Quesada and Jonathan Lavoie

Non-Hermitian chiral phononics through optomechanically induced squeezing pp. 82-87

Javier Pino, Jesse J. Slim and Ewold Verhagen

Epitaxial single-crystal hexagonal boron nitride multilayers on Ni (111) pp. 88-93

Kyung Yeol Ma, Leining Zhang, Sunghwan Jin, Yan Wang, Seong In Yoon, Hyuntae Hwang, Juseung Oh, Da Sol Jeong, Meihui Wang, Shahana Chatterjee, Gwangwoo Kim, A-Rang Jang, Jieun Yang, Sunmin Ryu, Hu Young Jeong, Rodney S. Ruoff, Manish Chhowalla, Feng Ding and Hyeon Suk Shin

A tissue-like neurotransmitter sensor for the brain and gut pp. 94-101

Jinxing Li, Yuxin Liu, Lei Yuan, Baibing Zhang, Estelle Spear Bishop, Kecheng Wang, Jing Tang, Yu-Qing Zheng, Wenhui Xu, Simiao Niu, Levent Beker, Thomas L. Li, Gan Chen, Modupeola Diyaolu, Anne-Laure Thomas, Vittorio Mottini, Jeffrey B.-H. Tok, James C. Y. Dunn, Bianxiao Cui, Sergiu P. Pașca, Yi Cui, Aida Habtezion, Xiaoke Chen and Zhenan Bao

[18F]Difluorocarbene for positron emission tomography pp. 102-108

Jeroen B. I. Sap, Claudio F. Meyer, Joseph Ford, Natan J. W. Straathof, Alexander B. Dürr, Mariah J. Lelos, Stephen J. Paisey, Tim A. Mollner, Sandrine M. Hell, Andrés A. Trabanco, Christophe Genicot, Christopher W. am Ende, Robert S. Paton, Matthew Tredwell and Véronique Gouverneur

Morphology of Palaeospondylus shows affinity to tetrapod ancestors pp. 109-112

Tatsuya Hirasawa, Yuzhi Hu, Kentaro Uesugi, Masato Hoshino, Makoto Manabe and Shigeru Kuratani

The mosaic oat genome gives insights into a uniquely healthy cereal crop pp. 113-119

Nadia Kamal, Nikos Tsardakas Renhuldt, Johan Bentzer, Heidrun Gundlach, Georg Haberer, Angéla Juhász, Thomas Lux, Utpal Bose, Jason A. Tye-Din, Daniel Lang, Nico Gessel, Ralf Reski, Yong-Bi Fu, Peter Spégel, Alf Ceplitis, Axel Himmelbach, Amanda J. Waters, Wubishet A. Bekele, Michelle L. Colgrave, Mats Hansson, Nils Stein, Klaus F. X. Mayer, Eric N. Jellen, Peter J. Maughan, Nicholas A. Tinker, Martin Mascher, Olof Olsson, Manuel Spannagl and Nick Sirijovski

Single-cell eQTL models reveal dynamic T cell state dependence of disease loci pp. 120-128

Aparna Nathan, Samira Asgari, Kazuyoshi Ishigaki, Cristian Valencia, Tiffany Amariuta, Yang Luo, Jessica I. Beynor, Yuriy Baglaenko, Sara Suliman, Alkes L. Price, Leonid Lecca, Megan B. Murray, D. Branch Moody and Soumya Raychaudhuri

People construct simplified mental representations to plan pp. 129-136

Mark K. Ho, David Abel, Carlos G. Correa, Michael L. Littman, Jonathan D. Cohen and Thomas L. Griffiths

Neuropathic pain caused by miswiring and abnormal end organ targeting pp. 137-145

Vijayan Gangadharan, Hongwei Zheng, Francisco J. Taberner, Jonathan Landry, Timo A. Nees, Jelena Pistolic, Nitin Agarwal, Deepitha Männich, Vladimir Benes, Moritz Helmstaedter, Björn Ommer, Stefan G. Lechner, Thomas Kuner and Rohini Kuner

CCR5 closes the temporal window for memory linking pp. 146-152

Yang Shen, Miou Zhou, Denise Cai, Daniel Almeida Filho, Giselle Fernandes, Ying Cai, André F. Sousa, Min Tian, Nury Kim, Jinsu Lee, Deanna Necula, Chengbin Zhou, Shuoyi Li, Shelbi Salinas, Andy Liu, Xiaoman Kang, Masakazu Kamata, Ayal Lavi, Shan Huang, Tawnie Silva, Won Do Heo and Alcino J. Silva

Gene regulation by gonadal hormone receptors underlies brain sex differences pp. 153-159

B. Gegenhuber, M. V. Wu, R. Bronstein and J. Tollkuhn

Distinct gene clusters drive formation of ferrosome organelles in bacteria pp. 160-164

Carly R. Grant, Matthieu Amor, Hector A. Trujillo, Sunaya Krishnapura, Anthony T. Iavarone and Arash Komeili

Developmental dynamics of two bipotent thymic epithelial progenitor types pp. 165-171

Anja Nusser, Sagar, Jeremy B. Swann, Brigitte Krauth, Dagmar Diekhoff, Lesly Calderon, Christiane Happe, Dominic Grün and Thomas Boehm

Fundamental immune–oncogenicity trade-offs define driver mutation fitness pp. 172-179

David Hoyos, Roberta Zappasodi, Isabell Schulze, Zachary Sethna, Kelvin César Andrade, Dean F. Bajorin, Chaitanya Bandlamudi, Margaret K. Callahan, Samuel A. Funt, Sine R. Hadrup, Jeppe S. Holm, Jonathan E. Rosenberg, Sohrab P. Shah, Ignacio Vázquez-García, Britta Weigelt, Michelle Wu, Dmitriy Zamarin, Laura F. Campitelli, Edward J. Osborne, Mark Klinger, Harlan S. Robins, Payal P. Khincha, Sharon A. Savage, Vinod P. Balachandran, Jedd D. Wolchok, Matthew D. Hellmann, Taha Merghoub, Arnold J. Levine, Marta Łuksza and Benjamin D. Greenbaum

Mitochondrial uncouplers induce proton leak by activating AAC and UCP1 pp. 180-187

Ambre M. Bertholet, Andrew M. Natale, Paola Bisignano, Junji Suzuki, Andriy Fedorenko, James Hamilton, Tatiana Brustovetsky, Lawrence Kazak, Ryan Garrity, Edward T. Chouchani, Nickolay Brustovetsky, Michael Grabe and Yuriy Kirichok

Gibbin mesodermal regulation patterns epithelial development pp. 188-196

Ann Collier, Angela Liu, Jessica Torkelson, Jillian Pattison, Sadhana Gaddam, Hanson Zhen, Tiffany Patel, Kelly McCarthy, Hana Ghanim and Anthony E. Oro

MCM complexes are barriers that restrict cohesin-mediated loop extrusion pp. 197-203

Bart J. H. Dequeker, Matthias J. Scherr, Hugo B. Brandão, Johanna Gassler, Sean Powell, Imre Gaspar, Ilya M. Flyamer, Aleksandar Lalic, Wen Tang, Roman Stocsits, Iain F. Davidson, Jan-Michael Peters, Karl E. Duderstadt, Leonid A. Mirny and Kikuë Tachibana

Fast and efficient DNA replication with purified human proteins pp. 204-210

Yasemin Baris, Martin R. G. Taylor, Valentina Aria and Joseph T. P. Yeeles

Has the ‘great resignation’ hit academia? pp. 211-213

Virginia Gewin

How engineers and drug developers are working to change childhood cancer’s deadly calculus pp. 214-215

Esther Landhuis

A down-to-earth approach to climate change pp. 218-218

Virginia Gewin