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2012, volume 492, articles 7429

Psoriasis pp. S49-S49

Michelle Grayson

Psoriasis uncovered pp. S50-S51

James Mitchell Crow

Immunology: A many layered thing pp. S52-S54

Claire Ainsworth

Perspective: Don't be superficial pp. S55-S55

Wolf-Henning Boehncke

Genetics: Deep exploration pp. S56-S57

Ken Garber

Therapeutics: Silencing psoriasis pp. S58-S59

James Mitchell Crow

Microbiome: The surface brigade pp. S60-S61

Bijal Trivedi

Psychodermatology: An emotional response pp. S62-S63

Sarah DeWeerdt

Q&A: Under their skin pp. S64-S65

Christopher Griffiths

Time to stop relying on things past pp. 313-313

David Goldston

Mega-array reveals birthplace of giant stars pp. 319-320

Eric Hand

Russia shakes up its universities pp. 320-320

Quirin Schiermeier

Big biotech buys iconic genetics firm pp. 321-321

Monya Baker

Global survey reveals impact of disability pp. 322-322

Declan Butler

China’s patent boom brings legal wrangles pp. 323-323

David Cyranoski

366 days: 2012 in review pp. 324-327

Richard Van Noorden

366 days: Images of the year pp. 328-333

Daniel Cressey and Mark Peplow

Self-censorship is not enough pp. 345-347

David Kaiser and Jonathan Moreno

Open access must enable open use pp. 348-349

Cameron Neylon

Viticulture: Fruity with a hint of drought pp. 351-352

Jamie Goode

Vintage scientists pp. 352-353

Jamie Goode

Natural history: Diamonds in the rough pp. 354-354

Ewen Callaway

Nutrition: Sugar caned pp. 355-355

David Katz

English not Latin in botanical reports pp. 356-356

Frank Udovicic

Thousand-citation papers are outliers pp. 356-356

James Woodgett

Invest proceeds of 4G sale in UK science pp. 356-356

Imran Khan and Stian Westlake

Cite links to data in reference lists pp. 356-356

Laurie Goodman, Rebecca Lawrence and Kevin Ashley

Quantum interference heats up pp. 358-359

Raymond W. Simmonds

Signalling pathways of fragile X syndrome pp. 359-360

Sabarinath Jayaseelan and Scott A. Tenenbaum

A boost for heart regeneration pp. 360-361

Mark Mercola

Metabolism in 'the driver's seat pp. 362-363

Luisa Tasselli and Katrin F. Chua

Erase for a new start pp. 363-364

Sylvain Guibert and Michael Weber

Cool molecules pp. 364-365

Paul S. Julienne

Go with the lows pp. 365-365

Andrew Mitchinson

Seventy-five genetic loci influencing the human red blood cell pp. 369-375

Pim van der Harst, Weihua Zhang, Irene Mateo Leach, Augusto Rendon, Niek Verweij, Joban Sehmi, Dirk S. Paul, Ulrich Elling, Hooman Allayee, Xinzhong Li, Aparna Radhakrishnan, Sian-Tsung Tan, Katrin Voss, Christian X. Weichenberger, Cornelis A. Albers, Abtehale Al-Hussani, Folkert W. Asselbergs, Marina Ciullo, Fabrice Danjou, Christian Dina, Tõnu Esko, David M. Evans, Lude Franke, Martin Gögele, Jaana Hartiala, Micha Hersch, Hilma Holm, Jouke-Jan Hottenga, Stavroula Kanoni, Marcus E. Kleber, Vasiliki Lagou, Claudia Langenberg, Lorna M. Lopez, Leo-Pekka Lyytikäinen, Olle Melander, Federico Murgia, Ilja M. Nolte, Paul F. O’Reilly, Sandosh Padmanabhan, Afshin Parsa, Nicola Pirastu, Eleonora Porcu, Laura Portas, Inga Prokopenko, Janina S. Ried, So-Youn Shin, Clara S. Tang, Alexander Teumer, Michela Traglia, Sheila Ulivi, Harm-Jan Westra, Jian Yang, Jing Hua Zhao, Franco Anni, Abdel Abdellaoui, Antony Attwood, Beverley Balkau, Stefania Bandinelli, François Bastardot, Beben Benyamin, Bernhard O. Boehm, William O. Cookson, Debashish Das, Paul I. W. de Bakker, Rudolf A. de Boer, Eco J. C. de Geus, Marleen H. de Moor, Maria Dimitriou, Francisco S. Domingues, Angela Döring, Gunnar Engström, Gudmundur Ingi Eyjolfsson, Luigi Ferrucci, Krista Fischer, Renzo Galanello, Stephen F. Garner, Bernd Genser, Quince D. Gibson, Giorgia Girotto, Daniel Fannar Gudbjartsson, Sarah E. Harris, Anna-Liisa Hartikainen, Claire E. Hastie, Bo Hedblad, Thomas Illig, Jennifer Jolley, Mika Kähönen, Ido P. Kema, John P. Kemp, Liming Liang, Heather Lloyd-Jones, Ruth J. F. Loos, Stuart Meacham, Sarah E. Medland, Christa Meisinger, Yasin Memari, Evelin Mihailov, Kathy Miller, Miriam F. Moffatt, Matthias Nauck, Maria Novatchkova, Teresa Nutile, Isleifur Olafsson, Pall T. Onundarson, Debora Parracciani, Brenda W. Penninx, Lucia Perseu, Antonio Piga, Giorgio Pistis, Anneli Pouta, Ursula Puc, Olli Raitakari, Susan M. Ring, Antonietta Robino, Daniela Ruggiero, Aimo Ruokonen, Aude Saint-Pierre, Cinzia Sala, Andres Salumets, Jennifer Sambrook, Hein Schepers, Carsten Oliver Schmidt, Herman H. W. Silljé, Rob Sladek, Johannes H. Smit, John M. Starr, Jonathan Stephens, Patrick Sulem, Toshiko Tanaka, Unnur Thorsteinsdottir, Vinicius Tragante, Wiek H. van Gilst, L. Joost van Pelt, Dirk J. van Veldhuisen, Uwe Völker, John B. Whitfield, Gonneke Willemsen, Bernhard R. Winkelmann, Gerald Wirnsberger, Ale Algra, Francesco Cucca, Adamo Pio d’Adamo, John Danesh, Ian J. Deary, Anna F. Dominiczak, Paul Elliott, Paolo Fortina, Philippe Froguel, Paolo Gasparini, Andreas Greinacher, Stanley L. Hazen, Marjo-Riitta Jarvelin, Kay Tee Khaw, Terho Lehtimäki, Winfried Maerz, Nicholas G. Martin, Andres Metspalu, Braxton D. Mitchell, Grant W. Montgomery, Carmel Moore, Gerjan Navis, Mario Pirastu, Peter P. Pramstaller, Ramiro Ramirez-Solis, Eric Schadt, James Scott, Alan R. Shuldiner, George Davey Smith, J. Gustav Smith, Harold Snieder, Rossella Sorice, Tim D. Spector, Kari Stefansson, Michael Stumvoll, W. H. Wilson Tang, Daniela Toniolo, Anke Tönjes, Peter M. Visscher, Peter Vollenweider, Nicholas J. Wareham, Bruce H. R. Wolffenbuttel, Dorret I. Boomsma, Jacques S. Beckmann, George V. Dedoussis, Panos Deloukas, Manuel A. Ferreira, Serena Sanna, Manuela Uda, Andrew A. Hicks, Josef Martin Penninger, Christian Gieger, Jaspal S. Kooner, Willem H. Ouwehand, Nicole Soranzo and John C. Chambers

Functional screening identifies miRNAs inducing cardiac regeneration pp. 376-381

Ana Eulalio, Miguel Mano, Matteo Dal Ferro, Lorena Zentilin, Gianfranco Sinagra, Serena Zacchigna and Mauro Giacca

FMRP targets distinct mRNA sequence elements to regulate protein expression pp. 382-386

Manuel Ascano, Neelanjan Mukherjee, Pradeep Bandaru, Jason B. Miller, Jeffrey D. Nusbaum, David L. Corcoran, Christine Langlois, Mathias Munschauer, Scott Dewell, Markus Hafner, Zev Williams, Uwe Ohler and Thomas Tuschl

High-resolution crystal structure of human protease-activated receptor 1 pp. 387-392

Cheng Zhang, Yoga Srinivasan, Daniel H. Arlow, Juan Jose Fung, Daniel Palmer, Yaowu Zheng, Hillary F. Green, Anjali Pandey, Ron O. Dror, David E. Shaw, William I. Weis, Shaun R. Coughlin and Brian K. Kobilka

Dynamical age differences among coeval star clusters as revealed by blue stragglers pp. 393-395

F. R. Ferraro, B. Lanzoni, E. Dalessandro, G. Beccari, M. Pasquato, P. Miocchi, R. T. Rood, S. Sigurdsson, A. Sills, E. Vesperini, M. Mapelli, R. Contreras, N. Sanna and A. Mucciarelli

Evaporative cooling of the dipolar hydroxyl radical pp. 396-400

Benjamin K. Stuhl, Matthew T. Hummon, Mark Yeo, Goulven Quéméner, John L. Bohn and Jun Ye

The Josephson heat interferometer pp. 401-405

Francesco Giazotto and María José Martínez-Pérez

Fractionalized excitations in the spin-liquid state of a kagome-lattice antiferromagnet pp. 406-410

Tian-Heng Han, Joel S. Helton, Shaoyan Chu, Daniel G. Nocera, Jose A. Rodriguez-Rivera, Collin Broholm and Young S. Lee

Quasi-cylindrical wave contribution in experiments on extraordinary optical transmission pp. 411-414

Frerik van Beijnum, Chris Rétif, Chris B. Smiet, Haitao Liu, Philippe Lalanne and Martin P. van Exter

Laboratory measurements of the viscous anisotropy of olivine aggregates pp. 415-418

L. N. Hansen, M. E. Zimmerman and D. L. Kohlstedt

Flickering gives early warning signals of a critical transition to a eutrophic lake state pp. 419-422

Rong Wang, John A. Dearing, Peter G. Langdon, Enlou Zhang, Xiangdong Yang, Vasilis Dakos and Marten Scheffer

Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres pp. 423-427

Andrew H. Paterson, Jonathan F. Wendel, Heidrun Gundlach, Hui Guo, Jerry Jenkins, Dianchuan Jin, Danny Llewellyn, Kurtis C. Showmaker, Shengqiang Shu, Joshua Udall, Mi-jeong Yoo, Robert Byers, Wei Chen, Adi Doron-Faigenboim, Mary V. Duke, Lei Gong, Jane Grimwood, Corrinne Grover, Kara Grupp, Guanjing Hu, Tae-ho Lee, Jingping Li, Lifeng Lin, Tao Liu, Barry S. Marler, Justin T. Page, Alison W. Roberts, Elisson Romanel, William S. Sanders, Emmanuel Szadkowski, Xu Tan, Haibao Tang, Chunming Xu, Jinpeng Wang, Zining Wang, Dong Zhang, Lan Zhang, Hamid Ashrafi, Frank Bedon, John E. Bowers, Curt L. Brubaker, Peng W. Chee, Sayan Das, Alan R. Gingle, Candace H. Haigler, David Harker, Lucia V. Hoffmann, Ran Hovav, Donald C. Jones, Cornelia Lemke, Shahid Mansoor, Mehboob ur Rahman, Lisa N. Rainville, Aditi Rambani, Umesh K. Reddy, Jun-kang Rong, Yehoshua Saranga, Brian E. Scheffler, Jodi A. Scheffler, David M. Stelly, Barbara A. Triplett, Allen Van Deynze, Maite F. S. Vaslin, Vijay N. Waghmare, Sally A. Walford, Robert J. Wright, Essam A. Zaki, Tianzhen Zhang, Elizabeth S. Dennis, Klaus F. X. Mayer, Daniel G. Peterson, Daniel S. Rokhsar, Xiyin Wang and Jeremy Schmutz

A prefrontal cortex–brainstem neuronal projection that controls response to behavioural challenge pp. 428-432

Melissa R. Warden, Aslihan Selimbeyoglu, Julie J. Mirzabekov, Maisie Lo, Kimberly R. Thompson, Sung-Yon Kim, Avishek Adhikari, Kay M. Tye, Loren M. Frank and Karl Deisseroth

Layered reward signalling through octopamine and dopamine in Drosophila pp. 433-437

Christopher J. Burke, Wolf Huetteroth, David Owald, Emmanuel Perisse, Michael J. Krashes, Gaurav Das, Daryl Gohl, Marion Silies, Sarah Certel and Scott Waddell

Somatic copy number mosaicism in human skin revealed by induced pluripotent stem cells pp. 438-442

Alexej Abyzov, Jessica Mariani, Dean Palejev, Ying Zhang, Michael Seamus Haney, Livia Tomasini, Anthony F. Ferrandino, Lior A. Rosenberg Belmaker, Anna Szekely, Michael Wilson, Arif Kocabas, Nathaniel E. Calixto, Elena L. Grigorenko, Anita Huttner, Katarzyna Chawarska, Sherman Weissman, Alexander Eckehart Urban, Mark Gerstein and Flora M. Vaccarino

Tet1 controls meiosis by regulating meiotic gene expression pp. 443-447

Shinpei Yamaguchi, Kwonho Hong, Rui Liu, Li Shen, Azusa Inoue, Dinh Diep, Kun Zhang and Yi Zhang

Structure of the Mediator head module pp. 448-451

Laurent Larivière, Clemens Plaschka, Martin Seizl, Larissa Wenzeck, Fabian Kurth and Patrick Cramer

Ventral tegmental area GABA projections pause accumbal cholinergic interneurons to enhance associative learning pp. 452-456

Matthew T. C. Brown, Kelly R. Tan, Eoin C. O’Connor, Irina Nikonenko, Dominique Muller and Christian Lüscher

Guiding lights pp. 457-458

Philip Campbell

Turning point: Julia Greer pp. 459-459

Virginia Gewin

Review of the year: 2062 pp. 462-462

John Gilbey

2012, volume 492, articles 7428

Treat obesity as physiology, not physics pp. 155-155

Gary Taubes

Duelling visions stall NASA pp. 161-162

Eric Hand

Ancient fungi found in deep-sea mud pp. 163-163

Richard Monastersky

Hopes surface for exotic insulator pp. 165-165

Eugenie Samuel Reich

Clusters of coronavirus cases put scientists on alert pp. 166-167

Declan Butler

NIH tackles major workforce issues pp. 167-167

Meredith Wadman

Cash injection set to revive Swiss drug site pp. 168-168

Daniel Cressey

Polar research: Trouble bares its claws pp. 170-172

Douglas Fox

Computer engineering: Feeling the heat pp. 174-176

Philip Ball

The 100-year mystery of Piltdown Man pp. 177-179

Chris Stringer

Know when your numbers are significant pp. 180-181

David L. Vaux

Genetics: Testing infant destinies pp. 182-183

Henry T. Greely

Science communication: Science fresh from the box pp. 184-185

Eugenie Scott

End the scandal of false cell lines pp. 186-186

John R. Masters

Settle discord over the Southern Ocean pp. 186-186

Philip N. Trathan

Romania needs overseas reviewers pp. 186-186

Illimar Altosaar

Put soil security on the global agenda pp. 186-186

Andrea Koch, Alex McBratney and Rattan Lal

A constructive debate pp. 188-189

Jay D. Keasling, Abraham Mendoza and Phil S. Baran

All clear for ribosome landing pp. 189-191

Harris D. Bernstein

A pas de trois birth for wide binary stars pp. 191-192

Keivan Guadalupe Stassun

Clearing up the dust pp. 192-192

Amy Barger

Conservation in the red pp. 193-194

Stephen Polasky

Death by deacetylation pp. 194-195

Wen Zhou and Junying Yuan

Molecular hurdles cleared with ease pp. 195-197

Michael A. Trakselis and Brian W. Graham

Molecules that convert heat into light pp. 197-197

Brian D'Andrade

The NAD-dependent deacetylase SIRT2 is required for programmed necrosis pp. 199-204

Nisha Narayan, In Hye Lee, Ronen Borenstein, Junhui Sun, Renee Wong, Guang Tong, Maria M. Fergusson, Jie Liu, Ilsa I. Rovira, Hwei-Ling Cheng, Guanghui Wang, Marjan Gucek, David Lombard, Fredrick W. Alt, Michael N. Sack, Elizabeth Murphy, Liu Cao and Toren Finkel

Bypass of a protein barrier by a replicative DNA helicase pp. 205-209

Hasan Yardimci, Xindan Wang, Anna B. Loveland, Inger Tappin, David Z. Rudner, Jerard Hurwitz, Antoine M. van Oijen and Johannes C. Walter

Structure of the TatC core of the twin-arginine protein transport system pp. 210-214

Sarah E. Rollauer, Michael J. Tarry, James E. Graham, Mari Jääskeläinen, Franziska Jäger, Steven Johnson, Martin Krehenbrink, Sai-Man Liu, Michael J. Lukey, Julien Marcoux, Melanie A. McDowell, Fernanda Rodriguez, Pietro Roversi, Phillip J. Stansfeld, Carol V. Robinson, Mark S. P. Sansom, Tracy Palmer, Martin Högbom, Ben C. Berks and Susan M. Lea

Automated design of ligands to polypharmacological profiles pp. 215-220

Jérémy Besnard, Gian Filippo Ruda, Vincent Setola, Keren Abecassis, Ramona M. Rodriguiz, Xi-Ping Huang, Suzanne Norval, Maria F. Sassano, Antony I. Shin, Lauren A. Webster, Frederick R. C. Simeons, Laste Stojanovski, Annik Prat, Nabil G. Seidah, Daniel B. Constam, G. Richard Bickerton, Kevin D. Read, William C. Wetsel, Ian H. Gilbert, Bryan L. Roth and Andrew L. Hopkins

Formation of the widest binary stars from dynamical unfolding of triple systems pp. 221-224

Bo Reipurth and Seppo Mikkola

An unexpectedly low oscillator strength as the origin of the Fe xvii emission problem pp. 225-228

S. Bernitt, G. V. Brown, J. K. Rudolph, R. Steinbrügge, A. Graf, M. Leutenegger, S. W. Epp, S. Eberle, K. Kubiček, V. Mäckel, M. C. Simon, E. Träbert, E. W. Magee, C. Beilmann, N. Hell, S. Schippers, A. Müller, S. M. Kahn, A. Surzhykov, Z. Harman, C. H. Keitel, J. Clementson, F. S. Porter, W. Schlotter, J. J. Turner, J. Ullrich, P. Beiersdorfer and J. R. Crespo López-Urrutia

Mid-infrared frequency comb based on a quantum cascade laser pp. 229-233

Andreas Hugi, Gustavo Villares, Stéphane Blaser, H. C. Liu and Jérôme Faist

Highly efficient organic light-emitting diodes from delayed fluorescence pp. 234-238

Hiroki Uoyama, Kenichi Goushi, Katsuyuki Shizu, Hiroko Nomura and Chihaya Adachi

Increased future ice discharge from Antarctica owing to higher snowfall pp. 239-242

R. Winkelmann, A. Levermann, M. A. Martin and K. Frieler

Deep penetration of molten iron into the mantle caused by a morphological instability pp. 243-246

Kazuhiko Otsuka and Shun-ichiro Karato

Nonlinear dendritic integration of sensory and motor input during an active sensing task pp. 247-251

Ning-long Xu, Mark T. Harnett, Stephen R. Williams, Daniel Huber, Daniel H. O’Connor, Karel Svoboda and Jeffrey C. Magee

Interleukin receptor activates a MYD88–ARNO–ARF6 cascade to disrupt vascular stability pp. 252-255

Weiquan Zhu, Nyall R. London, Christopher C. Gibson, Chadwick T. Davis, Zongzhong Tong, Lise K. Sorensen, Dallas S. Shi, Jinping Guo, Matthew C. P. Smith, Allie H. Grossmann, Kirk R. Thomas and Dean Y. Li

A soybean cyst nematode resistance gene points to a new mechanism of plant resistance to pathogens pp. 256-260

Shiming Liu, Pramod K. Kandoth, Samantha D. Warren, Greg Yeckel, Robert Heinz, John Alden, Chunling Yang, Aziz Jamai, Tarik El-Mellouki, Parijat S. Juvale, John Hill, Thomas J. Baum, Silvia Cianzio, Steven A. Whitham, Dmitry Korkin, Melissa G. Mitchum and Khalid Meksem

An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast pp. 261-265

Adam L. Hughes and Daniel E. Gottschling

Ubiquitin chain conformation regulates recognition and activity of interacting proteins pp. 266-270

Yu Ye, Georg Blaser, Mathew H. Horrocks, Maria J. Ruedas-Rama, Shehu Ibrahim, Alexander A. Zhukov, Angel Orte, David Klenerman, Sophie E. Jackson and David Komander

Activated GTPase movement on an RNA scaffold drives co-translational protein targeting pp. 271-275

Kuang Shen, Sinan Arslan, David Akopian, Taekjip Ha and Shu-ou Shan

Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesis pp. 276-279

Sergey Lekomtsev, Kuan-Chung Su, Valerie E. Pye, Ken Blight, Sriramkumar Sundaramoorthy, Tohru Takaki, Lucy M. Collinson, Peter Cherepanov, Nullin Divecha and Mark Petronczki

Regulation of ISWI involves inhibitory modules antagonized by nucleosomal epitopes pp. 280-284

Cedric R. Clapier and Bradley R. Cairns

The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity pp. 285-289

Jayakrishnan Nandakumar, Caitlin F. Bell, Ina Weidenfeld, Arthur J. Zaug, Leslie A. Leinwand and Thomas R. Cech

Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity pp. 290-290

Jordi Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A. Margolin, Sungjoon Kim, Christopher J.Wilson, Joseph Lehár, Gregory V. Kryukov, Dmitriy Sonkin, Anupama Reddy, Manway Liu, Lauren Murray, Michael F. Berger, John E. Monahan, Paula Morais, Jodi Meltzer, Adam Korejwa, Judit Jané-Valbuena, Felipa A. Mapa, Joseph Thibault, Eva Bric-Furlong, Pichai Raman, Aaron Shipway, Ingo H. Engels, Jill Cheng, Guoying K. Yu, Jianjun Yu, Peter Aspesi, Melanie de Silva, Kalpana Jagtap, Michael D. Jones, Li Wang, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Scott Mahan, Carrie Sougnez, Robert C. Onofrio, Ted Liefeld, Laura MacConaill, Wendy Winckler, Michael Reich, Nanxin Li, Jill P. Mesirov, Stacey B. Gabriel, Gad Getz, Kristin Ardlie, Vivien Chan, Vic E. Myer, Barbara L. Weber, Jeff Porter, Markus Warmuth, Peter Finan, Jennifer L. Harris, Matthew Meyerson, Todd R. Golub, Michael P. Morrissey, William R. Sellers, Robert Schlegel and Levi A. Garraway

Two microscopes are better than one pp. 293-297

Caitlin Smith

Lab life: Balancing act pp. 299-300

Quirin Schiermeier

Turning point: Patrik Rorsman pp. 301-301

Virginia Gewin

An unintended future pp. 304-304

Tristan Scott

2012, volume 492, articles 7427

Ageing pp. S1-S1

Michelle Grayson

Demography: To the limit pp. S2-S3

Tony Scully

Cognition: The brain's decline pp. S4-S5

Alison Abbott

Centenarians: Great expectations pp. S6-S8

Michael Eisenstein

Extinction need not be forever pp. 9-9

Subrat Kumar

Q&A Eva Kahana: Ageing proactively pp. S9-S9

Rebecca Kessler

Comparative biology: Looking for a master switch pp. S10-S11

Sarah Deweerdt

Stem cells: Repeat to fade pp. S12-S13

Peter Wehrwein

Microbiome: Cultural differences pp. S14-S15

Virginia Hughes

Flood of protest hits Indian dams pp. 15-16

Jane Qiu

Technology: Dancing with robots pp. S16-S17

Neil Savage

Nanoparticle blast caught on film pp. 16-17

Eugenie Samuel Reich

Quiet Texan to head science committee pp. 17-17

Helen Shen

Interventions: Live long and prosper pp. S18-S20

Katherine Bourzac

US advisers seek research overhaul pp. 18-18

Eric Hand

FDA under pressure to relax drug rules pp. 19-19

Heidi Ledford

Megacities move to track emissions pp. 20-21

Jeff Tollefson

Data teleportation: The quantum space race pp. 22-25

Zeeya Merali

Nuclear energy: Radical reactors pp. 26-29

M. Mitchell Waldrop

Thorium fuel has risks pp. 31-33

Stephen F. Ashley, Geoffrey T. Parks, William Nuttall, Colin Boxall and Robin W. Grimes

Conform and be funded pp. 34-36

Joshua M. Nicholson and John P. A. Ioannidis

X-Ray crystallography: Symmetry wars pp. 37-38

Philip Ball

Mathematics: Poet of the infinite pp. 38-39

George Szpiro

Q&A: Iceberg imager pp. 40-40

Jascha Hoffman

Research-reporting standards fall short pp. 41-41

David Baker, Katie Lidster, Ana Sottomayor and Sandra Amor

From pork lard to palm oil and back pp. 41-41

José Bonner

Strength to strength for mouse models pp. 41-41

Klaus Schughart, Claude Libert and Martien J. Kas

Eritrea should choose its own science path pp. 41-41

Andrew Isaac Meso

Farish A. Jenkins Jr (1940–2012) pp. 42-42

Neil Shubin

Intimate neuronal whispers pp. 44-45

Kazumichi Shimizu and Mark Stopfer

Toolkit of reagents to aid drug discovery pp. 45-46

William J. Pitts

Algae's complex origins pp. 46-48

Sven B. Gould

Astrophysical false positives pp. 48-49

Andrew Collier Cameron

Another aspect of nature's ingenuity pp. 50-51

Joe Chappell

An optical trampoline pp. 51-52

David McGloin

A truly embryonic star pp. 52-53

David A. Clarke

Stable allocations and market design pp. 54-55

Yan Chen and Jacob Goeree

Manipulating individual quantum systems pp. 55-55

Ed Hinds and Rainer Blatt

Mature cells can be rejuvenated pp. 56-56

Janet Rossant and Christine Mummery

Studies of a ubiquitous receptor family pp. 57-57

Bryan L. Roth and Fiona H. Marshall

Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs pp. 59-65

Bruce A. Curtis, Goro Tanifuji, Fabien Burki, Ansgar Gruber, Manuel Irimia, Shinichiro Maruyama, Maria C. Arias, Steven G. Ball, Gillian H. Gile, Yoshihisa Hirakawa, Julia F. Hopkins, Alan Kuo, Stefan A. Rensing, Jeremy Schmutz, Aikaterini Symeonidi, Marek Elias, Robert J. M. Eveleigh, Emily K. Herman, Mary J. Klute, Takuro Nakayama, Miroslav Oborník, Adrian Reyes-Prieto, E. Virginia Armbrust, Stephen J. Aves, Robert G. Beiko, Pedro Coutinho, Joel B. Dacks, Dion G. Durnford, Naomi M. Fast, Beverley R. Green, Cameron J. Grisdale, Franziska Hempel, Bernard Henrissat, Marc P. Höppner, Ken-Ichiro Ishida, Eunsoo Kim, Luděk Kořený, Peter G. Kroth, Yuan Liu, Shehre-Banoo Malik, Uwe G. Maier, Darcy McRose, Thomas Mock, Jonathan A. D. Neilson, Naoko T. Onodera, Anthony M. Poole, Ellen J. Pritham, Thomas A. Richards, Gabrielle Rocap, Scott W. Roy, Chihiro Sarai, Sarah Schaack, Shu Shirato, Claudio H. Slamovits, David F. Spencer, Shigekatsu Suzuki, Alexandra Z. Worden, Stefan Zauner, Kerrie Barry, Callum Bell, Arvind K. Bharti, John A. Crow, Jane Grimwood, Robin Kramer, Erika Lindquist, Susan Lucas, Asaf Salamov, Geoffrey I. McFadden, Christopher E. Lane, Patrick J. Keeling, Michael W. Gray, Igor V. Grigoriev and John M. Archibald

Non-synaptic inhibition between grouped neurons in an olfactory circuit pp. 66-71

Chih-Ying Su, Karen Menuz, Johannes Reisert and John R. Carlson

The entorhinal grid map is discretized pp. 72-78

Hanne Stensola, Tor Stensola, Trygve Solstad, Kristian Frøland, May-Britt Moser and Edvard I. Moser

Extremely metal-poor gas at a redshift of 7 pp. 79-82

Robert A. Simcoe, Peter W. Sullivan, Kathy L. Cooksey, Melodie M. Kao, Michael S. Matejek and Adam J. Burgasser

A ∼0.2-solar-mass protostar with a Keplerian disk in the very young L1527 IRS system pp. 83-85

John J. Tobin, Lee Hartmann, Hsin-Fang Chiang, David J. Wilner, Leslie W. Looney, Laurent Loinard, Nuria Calvet and Paola D’Alessio

Controlled-reflectance surfaces with film-coupled colloidal nanoantennas pp. 86-89

Antoine Moreau, Cristian Ciracì, Jack J. Mock, Ryan T. Hill, Qiang Wang, Benjamin J. Wiley, Ashutosh Chilkoti and David R. Smith

Continuous gas-phase synthesis of nanowires with tunable properties pp. 90-94

Magnus Heurlin, Martin H. Magnusson, David Lindgren, Martin Ek, L. Reine Wallenberg, Knut Deppert and Lars Samuelson

Practical and innate carbon–hydrogen functionalization of heterocycles pp. 95-99

Yuta Fujiwara, Janice A. Dixon, Fionn O’Hara, Erik Daa Funder, Darryl D. Dixon, Rodrigo A. Rodriguez, Ryan D. Baxter, Bart Herlé, Neal Sach, Michael R. Collins, Yoshihiro Ishihara and Phil S. Baran

The root of branching river networks pp. 100-103

J. Taylor Perron, Paul W. Richardson, Ken L. Ferrier and Mathieu Lapôtre

Identification of a rudimentary neural crest in a non-vertebrate chordate pp. 104-107

Philip Barron Abitua, Eileen Wagner, Ignacio A. Navarrete and Michael Levine

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations pp. 108-112

Michael T. McCabe, Heidi M. Ott, Gopinath Ganji, Susan Korenchuk, Christine Thompson, Glenn S. Van Aller, Yan Liu, Alan P. Graves, Anthony Della Pietra, Elsie Diaz, Louis V. LaFrance, Mark Mellinger, Celine Duquenne, Xinrong Tian, Ryan G. Kruger, Charles F. McHugh, Martin Brandt, William H. Miller, Dashyant Dhanak, Sharad K. Verma, Peter J. Tummino and Caretha L. Creasy

Fucose sensing regulates bacterial intestinal colonization pp. 113-117

Alline R. Pacheco, Meredith M. Curtis, Jennifer M. Ritchie, Diana Munera, Matthew K. Waldor, Cristiano G. Moreira and Vanessa Sperandio

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice pp. 118-122

Florian Klein, Ariel Halper-Stromberg, Joshua A. Horwitz, Henning Gruell, Johannes F. Scheid, Stylianos Bournazos, Hugo Mouquet, Linda A. Spatz, Ron Diskin, Alexander Abadir, Trinity Zang, Marcus Dorner, Eva Billerbeck, Rachael N. Labitt, Christian Gaebler, Paola M. Marcovecchio, Reha-Baris Incesu, Thomas R. Eisenreich, Paul D. Bieniasz, Michael S. Seaman, Pamela J. Bjorkman, Jeffrey V. Ravetch, Alexander Ploss and Michel C. Nussenzweig

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP pp. 123-127

Geun-Shik Lee, Naeha Subramanian, Andrew I. Kim, Ivona Aksentijevich, Raphaela Goldbach-Mansky, David B. Sacks, Ronald N. Germain, Daniel L. Kastner and Jae Jin Chae

Structure of a force-conveying cadherin bond essential for inner-ear mechanotransduction pp. 128-132

Marcos Sotomayor, Wilhelm A. Weihofen, Rachelle Gaudet and David P. Corey

B12 cofactors directly stabilize an mRNA regulatory switch pp. 133-137

James E. Johnson, Francis E. Reyes, Jacob T. Polaski and Robert T. Batey

An alternative route to cyclic terpenes by reductive cyclization in iridoid biosynthesis pp. 138-142

Fernando Geu-Flores, Nathaniel H. Sherden, Vincent Courdavault, Vincent Burlat, Weslee S. Glenn, Cen Wu, Ezekiel Nims, Yuehua Cui and Sarah E. O’Connor

Drug discovery: A helping hand pp. 143-145

Trisha Gura

Time and again pp. 148-148

Moshe Sipper