Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes

Xiaoting Wang, Naruhisa Ota, Paolo Manzanillo, Lance Kates, Jose Zavala-Solorio, Celine Eidenschenk, Juan Zhang, Justin Lesch, Wyne P. Lee, Jed Ross, Lauri Diehl, Nicholas van Bruggen, Ganesh Kolumam () and Wenjun Ouyang ()
Additional contact information
Xiaoting Wang: Genentech
Naruhisa Ota: Genentech
Paolo Manzanillo: Genentech
Lance Kates: Genentech
Jose Zavala-Solorio: Genentech
Celine Eidenschenk: Genentech
Juan Zhang: Genentech
Justin Lesch: Genentech
Wyne P. Lee: Genentech
Jed Ross: Genentech
Lauri Diehl: Genentech
Nicholas van Bruggen: Genentech
Ganesh Kolumam: Genentech
Wenjun Ouyang: Genentech

Nature, 2014, vol. 514, issue 7521, 237-241

Abstract: In pre-clinical mouse models, the interleukin-22 pathway is identified as a novel target for therapeutic intervention in metabolic diseases.

Date: 2014
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DOI: 10.1038/nature13564

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