Conditional tolerance of temperate phages via transcription-dependent CRISPR-Cas targeting

Gregory W. Goldberg, Wenyan Jiang, David Bikard and Luciano A. Marraffini ()
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Gregory W. Goldberg: Laboratory of Bacteriology, The Rockefeller University, New York, New York 10065, USA
Wenyan Jiang: Laboratory of Bacteriology, The Rockefeller University, New York, New York 10065, USA
David Bikard: Laboratory of Bacteriology, The Rockefeller University, New York, New York 10065, USA
Luciano A. Marraffini: Laboratory of Bacteriology, The Rockefeller University, New York, New York 10065, USA

Nature, 2014, vol. 514, issue 7524, 633-637

Abstract: The Staphylococcus epidermidis CRISPR-Cas system can prevent lytic infection but tolerate lysogenization by temperate phage through a transcription-dependent DNA targeting mechanism.

Date: 2014
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DOI: 10.1038/nature13637

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