Required enhancer–matrin-3 network interactions for a homeodomain transcription program

Dorota Skowronska-Krawczyk (), Qi Ma, Michal Schwartz, Kathleen Scully, Wenbo Li, Zhijie Liu, Havilah Taylor, Jessica Tollkuhn, Kenneth A. Ohgi, Dimple Notani, Yoshinori Kohwi, Terumi Kohwi-Shigematsu and Michael G. Rosenfeld ()
Additional contact information
Dorota Skowronska-Krawczyk: Howard Hughes Medical Institute, School of Medicine, University of California, San Diego, La Jolla, California 92093, USA
Qi Ma: Howard Hughes Medical Institute, School of Medicine, University of California, San Diego, La Jolla, California 92093, USA
Michal Schwartz: Howard Hughes Medical Institute, School of Medicine, University of California, San Diego, La Jolla, California 92093, USA
Kathleen Scully: Howard Hughes Medical Institute, School of Medicine, University of California, San Diego, La Jolla, California 92093, USA
Wenbo Li: Howard Hughes Medical Institute, School of Medicine, University of California, San Diego, La Jolla, California 92093, USA
Zhijie Liu: Howard Hughes Medical Institute, School of Medicine, University of California, San Diego, La Jolla, California 92093, USA
Havilah Taylor: Howard Hughes Medical Institute, School of Medicine, University of California, San Diego, La Jolla, California 92093, USA
Jessica Tollkuhn: Howard Hughes Medical Institute, School of Medicine, University of California, San Diego, La Jolla, California 92093, USA
Kenneth A. Ohgi: Howard Hughes Medical Institute, School of Medicine, University of California, San Diego, La Jolla, California 92093, USA
Dimple Notani: Howard Hughes Medical Institute, School of Medicine, University of California, San Diego, La Jolla, California 92093, USA
Yoshinori Kohwi: Lawrence Berkeley National Laboratory
Terumi Kohwi-Shigematsu: Lawrence Berkeley National Laboratory
Michael G. Rosenfeld: Howard Hughes Medical Institute, School of Medicine, University of California, San Diego, La Jolla, California 92093, USA

Nature, 2014, vol. 514, issue 7521, 257-261

Abstract: The POU homeodomain transcription factor Pit1 is required for pituitary development; here Pit1-occupied enhancers are shown to interact with the nuclear architecture components matrin-3 and Satb1, and this association is required for activation of Pit1-regulated enhancers and coding target genes.

Date: 2014
References: Add references at CitEc
Citations: View citations in EconPapers (1)

Downloads: (external link)
https://www.nature.com/articles/nature13573 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:514:y:2014:i:7521:d:10.1038_nature13573

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature13573

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().