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2011, volume 478, articles 7370

Piecemeal cuts won't add up to radical reductions pp. 429-429

Jane C S Long

Fallout forensics hike radiation toll pp. 435-436

Geoff Brumfiel

US bill targets grantee salaries pp. 438-438

Meredith Wadman

Malaria vaccine results face scrutiny pp. 439-440

Declan Butler

Fetal gene screening comes to market pp. 440-440

Erika Check Hayden

European ban on stem-cell patents has a silver lining pp. 441-441

Ewen Callaway

Tissue-bank shortage: Brain child pp. 442-443

Alison Abbott

Plague genome: The Black Death decoded pp. 444-446

Ewen Callaway

Migration as adaptation pp. 447-449

Richard Black, Stephen R. G. Bennett, Sandy M. Thomas and John R. Beddington

The next dust bowl pp. 450-451

Joseph Romm

Psychology: A farewell to arms pp. 453-454

Martin Daly

Sociology: The illustrated scientist pp. 454-455

Margo DeMello

Biotechnology: DNA dollars pp. 456-456

Linnaea Ostroff

Q&A: The mathemagician pp. 457-457

Jascha Hoffman

Iraq's unseen burden of wounded civilians pp. 458-458

Gilles Guerrier, Emmanuel Baron, Rasheed Fakri and Isabelle Mouniaman

Brazil's forest code puts wetlands at risk pp. 458-458

Paulo Teixeira de Sousa, Maria Teresa Fernandez Piedade and Ennio Candotti

Small colleges aided by research networks pp. 458-458

Erin S. Lindquist, Laurel J. Anderson and Jeffrey A. Simmons

Aboriginal people agreed to DNA study pp. 458-459

Craig Muller

Give more priority to phosphorus studies pp. 459-459

Caroline P. Slomp

Boost resilience to tackle mental illness pp. 459-459

Oliver J. Robinson

Ralph Steinman (1943–2011) pp. 460-460

Michel C. Nussenzweig and Ira Mellman

An Arctic ozone hole? pp. 462-463

Rolando R. Garcia

Suicide of a protein pp. 463-464

Peter Roach

Eris under scrutiny pp. 464-465

Amanda Gulbis

Plague's progress pp. 465-466

Edward C. Holmes

Shedding light on the fabric of space-time pp. 466-467

Giovanni Amelino-Camelia

More than a bystander pp. 467-468

Philip Ball

Unprecedented Arctic ozone loss in 2011 pp. 469-475

Gloria L. Manney, Michelle L. Santee, Markus Rex, Nathaniel J. Livesey, Michael C. Pitts, Pepijn Veefkind, Eric R. Nash, Ingo Wohltmann, Ralph Lehmann, Lucien Froidevaux, Lamont R. Poole, Mark R. Schoeberl, David P. Haffner, Jonathan Davies, Valery Dorokhov, Hartwig Gernandt, Bryan Johnson, Rigel Kivi, Esko Kyrö, Niels Larsen, Pieternel F. Levelt, Alexander Makshtas, C. Thomas McElroy, Hideaki Nakajima, Maria Concepción Parrondo, David W. Tarasick, Peter von der Gathen, Kaley A. Walker and Nikita S. Zinoviev

A high-resolution map of human evolutionary constraint using 29 mammals pp. 476-482

Kerstin Lindblad-Toh, Manuel Garber, Or Zuk, Michael F. Lin, Brian J. Parker, Stefan Washietl, Pouya Kheradpour, Jason Ernst, Gregory Jordan, Evan Mauceli, Lucas D. Ward, Craig B. Lowe, Alisha K. Holloway, Michele Clamp, Sante Gnerre, Jessica Alföldi, Kathryn Beal, Jean Chang, Hiram Clawson, James Cuff, Federica Di Palma, Stephen Fitzgerald, Paul Flicek, Mitchell Guttman, Melissa J. Hubisz, David B. Jaffe, Irwin Jungreis, W. James Kent, Dennis Kostka, Marcia Lara, Andre L. Martins, Tim Massingham, Ida Moltke, Brian J. Raney, Matthew D. Rasmussen, Jim Robinson, Alexander Stark, Albert J. Vilella, Jiayu Wen, Xiaohui Xie, Michael C. Zody, Kim C. Worley, Christie L. Kovar, Donna M. Muzny, Richard A. Gibbs, Wesley C. Warren, Elaine R. Mardis, George M. Weinstock, Richard K. Wilson, Ewan Birney, Elliott H. Margulies, Javier Herrero, Eric D. Green, David Haussler, Adam Siepel, Nick Goldman, Katherine S. Pollard, Jakob S. Pedersen, Eric S. Lander and Manolis Kellis

Spatio-temporal transcriptome of the human brain pp. 483-489

Hyo Jung Kang, Yuka Imamura Kawasawa, Feng Cheng, Ying Zhu, Xuming Xu, Mingfeng Li, André M. M. Sousa, Mihovil Pletikos, Kyle A. Meyer, Goran Sedmak, Tobias Guennel, Yurae Shin, Matthew B. Johnson, Željka Krsnik, Simone Mayer, Sofia Fertuzinhos, Sheila Umlauf, Steven N. Lisgo, Alexander Vortmeyer, Daniel R. Weinberger, Shrikant Mane, Thomas M. Hyde, Anita Huttner, Mark Reimers, Joel E. Kleinman and Nenad Šestan

Kelvin–Helmholtz instabilities as the source of inhomogeneous mixing in nova explosions pp. 490-492

Jordi Casanova, Jordi José, Enrique García-Berro, Steven N. Shore and Alan C. Calder

A Pluto-like radius and a high albedo for the dwarf planet Eris from an occultation pp. 493-496

B. Sicardy, J. L. Ortiz, M. Assafin, E. Jehin, A. Maury, E. Lellouch, R. Gil Hutton, F. Braga-Ribas, F. Colas, D. Hestroffer, J. Lecacheux, F. Roques, P. Santos-Sanz, T. Widemann, N. Morales, R. Duffard, A. Thirouin, A. J. Castro-Tirado, M. Jelínek, P. Kubánek, A. Sota, R. Sánchez-Ramírez, A. H. Andrei, J. I. B. Camargo, D. N. da Silva Neto, A. Ramos Gomes, R. Vieira Martins, M. Gillon, J. Manfroid, G. P. Tozzi, C. Harlingten, S. Saravia, R. Behrend, S. Mottola, E. García Melendo, V. Peris, J. Fabregat, J. M. Madiedo, L. Cuesta, M. T. Eibe, A. Ullán, F. Organero, S. Pastor, J. A. de los Reyes, S. Pedraz, A. Castro, I. de la Cueva, G. Muler, I. A. Steele, M. Cebrián, P. Montañés-Rodríguez, A. Oscoz, D. Weaver, C. Jacques, W. J. B. Corradi, F. P. Santos, W. Reis, A. Milone, M. Emilio, L. Gutiérrez, R. Vázquez and H. Hernández-Toledo

Laser cooling and real-time measurement of the nuclear spin environment of a solid-state qubit pp. 497-501

E. Togan, Y. Chu, A. Imamoglu and M. D. Lukin

Structure and reactivity of a mononuclear non-haem iron(III)–peroxo complex pp. 502-505

Jaeheung Cho, Sujin Jeon, Samuel A. Wilson, Lei V. Liu, Eun A. Kang, Joseph J. Braymer, Mi Hee Lim, Britt Hedman, Keith O. Hodgson, Joan Selverstone Valentine, Edward I. Solomon and Wonwoo Nam

A draft genome of Yersinia pestis from victims of the Black Death pp. 506-510

Kirsten I. Bos, Verena J. Schuenemann, G. Brian Golding, Hernán A. Burbano, Nicholas Waglechner, Brian K. Coombes, Joseph B. McPhee, Sharon N. DeWitte, Matthias Meyer, Sarah Schmedes, James Wood, David J. D. Earn, D. Ann Herring, Peter Bauer, Hendrik N. Poinar and Johannes Krause

A natural polymorphism alters odour and DEET sensitivity in an insect odorant receptor pp. 511-514

Maurizio Pellegrino, Nicole Steinbach, Marcus C. Stensmyr, Bill S. Hansson and Leslie B. Vosshall

STING is a direct innate immune sensor of cyclic di-GMP pp. 515-518

Dara L. Burdette, Kathryn M. Monroe, Katia Sotelo-Troha, Jeff S. Iwig, Barbara Eckert, Mamoru Hyodo, Yoshihiro Hayakawa and Russell E. Vance

Temporal dynamics and genetic control of transcription in the human prefrontal cortex pp. 519-523

Carlo Colantuoni, Barbara K. Lipska, Tianzhang Ye, Thomas M. Hyde, Ran Tao, Jeffrey T. Leek, Elizabeth A. Colantuoni, Abdel G. Elkahloun, Mary M. Herman, Daniel R. Weinberger and Joel E. Kleinman

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia pp. 524-528

Johannes Zuber, Junwei Shi, Eric Wang, Amy R. Rappaport, Harald Herrmann, Edward A. Sison, Daniel Magoon, Jun Qi, Katharina Blatt, Mark Wunderlich, Meredith J. Taylor, Christopher Johns, Agustin Chicas, James C. Mulloy, Scott C. Kogan, Patrick Brown, Peter Valent, James E. Bradner, Scott W. Lowe and Christopher R. Vakoc

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia pp. 529-533

Mark A. Dawson, Rab K. Prinjha, Antje Dittmann, George Giotopoulos, Marcus Bantscheff, Wai-In Chan, Samuel C. Robson, Chun-wa Chung, Carsten Hopf, Mikhail M. Savitski, Carola Huthmacher, Emma Gudgin, Dave Lugo, Soren Beinke, Trevor D. Chapman, Emma J. Roberts, Peter E. Soden, Kurt R. Auger, Olivier Mirguet, Konstanze Doehner, Ruud Delwel, Alan K. Burnett, Phillip Jeffrey, Gerard Drewes, Kevin Lee, Brian J. P. Huntly and Tony Kouzarides

Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase pp. 534-537

Juan Du, Rafael F. Say, Wei Lü, Georg Fuchs and Oliver Einsle

Structural basis for the bifunctionality of fructose-1,6-bisphosphate aldolase/phosphatase pp. 538-541

Shinya Fushinobu, Hiroshi Nishimasu, Daiki Hattori, Hyun-Jin Song and Takayoshi Wakagi

Saccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthase pp. 542-546

Abhishek Chatterjee, N. Dinuka Abeydeera, Shridhar Bale, Pei-Jing Pai, Pieter C. Dorrestein, David H. Russell, Steven E. Ealick and Tadhg P. Begley

France: Peak of potential pp. 547-548

Katharine Sanderson

Turning point: Josefina del Mármol pp. 549-549

Karen Kaplan

An easy sale pp. 552-552

Biren Shah

2011, volume 478, articles 7369

Few inputs can reprogram biological networks pp. E4-E4

Franz-Josef Müller and Andreas Schuppert

Liu et al. reply pp. E4-E5

Yang-Yu Liu, Jean-Jacques Slotine and Albert-László Barabási

Genomic medicine has failed the poor pp. 287-287

Stephen Baker

Angry words over East Asian seas pp. 293-294

David Cyranoski

US row threatens Chinese links pp. 294-295

Eugenie Samuel Reich

No quick fix for Haiti cholera pp. 295-296

Declan Butler

Vatican bids for Italian institute pp. 296-297

Alison Abbott

Lobbyists confront US budget crunch pp. 299-299

Eugenie Samuel Reich

Seven billion and counting pp. 300-300

Jeff Tollefson

Spies to use Twitter as crystal ball pp. 301-301

Sharon Weinberger

Collaborative physics: String theory finds a bench mate pp. 302-304

Zeeya Merali

Dam controversy: Remaking the Mekong pp. 305-307

Gayathri Vaidyanathan

Taming the devil within us pp. 309-311

Steven Pinker

Treat donors as partners in biobank research pp. 312-313

Krishanu Saha and J. Benjamin Hurlbut

Evolution: Lies we tell ourselves pp. 314-315

Stuart West

Particle physics: A question of mass pp. 315-316

Edwin Cartlidge

Fiction: Gaming, guns and virtual gold pp. 317-317

John Gilbey

Medicine: Sex and freedom pp. 318-318

W. F. Bynum

Virology: Pathogenic passengers pp. 319-320

Edward C. Holmes

Technology: The inspiration exchange pp. 320-321

Chris Lintott

Neuroscience: Capturing free will pp. 322-323

Jacek Debiec

Rid Russian science of corruption pp. 324-324

Mikhail Gelfand

Italian quake: critics' logic is questionable pp. 324-324

John E. Vidale

Italian quake: science rides politics pp. 324-324

Benedetto De Vivo

Rudolf L. Mössbauer (1929–2011) pp. 325-325

Fritz Parak

Sterile neutrinos pp. 328-329

William C. Louis

Skin-cancer stem cells outwitted pp. 329-330

Salvador Aznar Benitah

Deft tricks with liquid crystals pp. 330-331

Ivan I. Smalyukh

Stars acquire youth through duplicity pp. 331-332

Christopher Tout

Gone with the wean pp. 333-334

Jon I. Arellano and Pasko Rakic

Many faces of a cancer-supporting protein pp. 334-335

John F. Darby and Paul Workman

Solutions for a cultivated planet pp. 337-342

Jonathan A. Foley, Navin Ramankutty, Kate A. Brauman, Emily S. Cassidy, James S. Gerber, Matt Johnston, Nathaniel D. Mueller, Christine O’Connell, Deepak K. Ray, Paul C. West, Christian Balzer, Elena M. Bennett, Stephen R. Carpenter, Jason Hill, Chad Monfreda, Stephen Polasky, Johan Rockström, John Sheehan, Stefan Siebert, David Tilman and David P. M. Zaks

The evolution of gene expression levels in mammalian organs pp. 343-348

David Brawand, Magali Soumillon, Anamaria Necsulea, Philippe Julien, Gábor Csárdi, Patrick Harrigan, Manuela Weier, Angélica Liechti, Ayinuer Aximu-Petri, Martin Kircher, Frank W. Albert, Ulrich Zeller, Philipp Khaitovich, Frank Grützner, Sven Bergmann, Rasmus Nielsen, Svante Pääbo and Henrik Kaessmann

PDGF signalling controls age-dependent proliferation in pancreatic β-cells pp. 349-355

Hainan Chen, Xueying Gu, Yinghua Liu, Jing Wang, Stacey E. Wirt, Rita Bottino, Hubert Schorle, Julien Sage and Seung K. Kim

A mass transfer origin for blue stragglers in NGC 188 as revealed by half-solar-mass companions pp. 356-359

Aaron M. Geller and Robert D. Mathieu

Efficient quantum computing using coherent photon conversion pp. 360-363

N. K. Langford, S. Ramelow, R. Prevedel, W. J. Munro, G. J. Milburn and A. Zeilinger

Biomimetic self-templating supramolecular structures pp. 364-368

Woo-Jae Chung, Jin-Woo Oh, Kyungwon Kwak, Byung Yang Lee, Joel Meyer, Eddie Wang, Alexander Hexemer and Seung-Wuk Lee

Aerobic bacterial pyrite oxidation and acid rock drainage during the Great Oxidation Event pp. 369-373

Kurt O. Konhauser, Stefan V. Lalonde, Noah J. Planavsky, Ernesto Pecoits, Timothy W. Lyons, Stephen J. Mojzsis, Olivier J. Rouxel, Mark E. Barley, Carlos Rosìere, Phillip W. Fralick, Lee R. Kump and Andrey Bekker

The role of dyking and fault control in the rapid onset of eruption at Chaitén volcano, Chile pp. 374-377

Charles Wicks, Juan Carlos de la Llera, Luis E. Lara and Jacob Lowenstern

Primary forests are irreplaceable for sustaining tropical biodiversity pp. 378-381

Luke Gibson, Tien Ming Lee, Lian Pin Koh, Barry W. Brook, Toby A. Gardner, Jos Barlow, Carlos A. Peres, Corey J. A. Bradshaw, William F. Laurance, Thomas E. Lovejoy and Navjot S. Sodhi

Corridors of migrating neurons in the human brain and their decline during infancy pp. 382-386

Nader Sanai, Thuhien Nguyen, Rebecca A. Ihrie, Zaman Mirzadeh, Hui-Hsin Tsai, Michael Wong, Nalin Gupta, Mitchel S. Berger, Eric Huang, Jose-Manuel Garcia-Verdugo, David H. Rowitch and Arturo Alvarez-Buylla

Primary motor cortex underlies multi-joint integration for fast feedback control pp. 387-390

J. Andrew Pruszynski, Isaac Kurtzer, Joseph Y. Nashed, Mohsen Omrani, Brenda Brouwer and Stephen H. Scott

Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells pp. 391-394

Kosuke Yusa, S. Tamir Rashid, Helene Strick-Marchand, Ignacio Varela, Pei-Qi Liu, David E. Paschon, Elena Miranda, Adriana Ordóñez, Nicholas R. F. Hannan, Foad J. Rouhani, Sylvie Darche, Graeme Alexander, Stefan J. Marciniak, Noemi Fusaki, Mamoru Hasegawa, Michael C. Holmes, James P. Di Santo, David A. Lomas, Allan Bradley and Ludovic Vallier

Metabolic priming by a secreted fungal effector pp. 395-398

Armin Djamei, Kerstin Schipper, Franziska Rabe, Anupama Ghosh, Volker Vincon, Jörg Kahnt, Sonia Osorio, Takayuki Tohge, Alisdair R. Fernie, Ivo Feussner, Kirstin Feussner, Peter Meinicke, York-Dieter Stierhof, Heinz Schwarz, Boris Macek, Matthias Mann and Regine Kahmann

A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours pp. 399-403

Benjamin Beck, Gregory Driessens, Steven Goossens, Khalil Kass Youssef, Anna Kuchnio, Amélie Caauwe, Panagiota A. Sotiropoulou, Sonja Loges, Gaelle Lapouge, Aurélie Candi, Guilhem Mascre, Benjamin Drogat, Sophie Dekoninck, Jody J. Haigh, Peter Carmeliet and Cédric Blanpain

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides pp. 404-407

Katey J. Rayner, Christine C. Esau, Farah N. Hussain, Allison L. McDaniel, Stephanie M. Marshall, Janine M. van Gils, Tathagat D. Ray, Frederick J. Sheedy, Leigh Goedeke, Xueqing Liu, Oleg G. Khatsenko, Vivek Kaimal, Cynthia J. Lees, Carlos Fernandez-Hernando, Edward A. Fisher, Ryan E. Temel and Kathryn J. Moore

Crystal structure of a bacterial homologue of the bile acid sodium symporter ASBT pp. 408-411

Nien-Jen Hu, So Iwata, Alexander D. Cameron and David Drew

Evolution of a new enzyme for carbon disulphide conversion by an acidothermophilic archaeon pp. 412-416

Marjan J. Smeulders, Thomas R. M. Barends, Arjan Pol, Anna Scherer, Marcel H. Zandvoort, Anikó Udvarhelyi, Ahmad F. Khadem, Andreas Menzel, John Hermans, Robert L. Shoeman, Hans J. C. T. Wessels, Lambert P. van den Heuvel, Lina Russ, Ilme Schlichting, Mike S. M. Jetten and Huub J. M. Op den Camp

Distance learning: Online education pp. 417-418

Sarah Kellogg

The athletes of science pp. 419-419

Maria Pavlou and Eleftherios P. Diamandis

You, in emulation pp. 422-422

Kathryn Cramer

2011, volume 478, articles 7368

InsP3R channel gating altered by clustering? pp. E1-E2

Horia Vais, J. Kevin Foskett and Don-On Daniel Mak

I speak a little maths pp. 1-1

Mariano Loza-Coll

When I grow up pp. 1-1

Lucie Low

Medical research masterclass pp. S1-S1

Michelle Grayson

Rahman et al. reply pp. E2-E3

Taufiq Rahman, Alexander Skupin, Martin Falcke and Colin W. Taylor

Lunchtime science pp. S2-S3

Thomas Arthur Steitz

On the wings of imagination pp. S4-S4

Aaron Ciechanover

Biochemistry without boundaries pp. S5-S5

Edmond Henri Fischer

Tough science pp. S6-S7

Ada Etil Yonath

Rational enthusiasm pp. S8-S9

Jean-Marie Lehn

Heart of science pp. S10-S11

Ferid Murad

Science addict pp. S12-S12

Harald zur Hausen

Telomeres: All's well that ends well pp. S13-S15

Michael Eisenstein

Translational research: The American way pp. S16-S18

Amy Maxmen

Masterclass: The gathering brainstorm pp. S19-S20

Kat McGowan

Marine protection in the Arctic cannot wait pp. 157-157

Lawson Brigham

A fight for life that united a field pp. 163-164

Lauren Gravitz

Persistence pays off for crystal chemist pp. 165-166

Richard Van Noorden

Sun-watchers hope giant telescope will get green light pp. 166-167

Eric Hand

Brazil cooks up transgenic bean pp. 168-168

Jeff Tollefson

France toughens conflict rules pp. 169-169

Declan Butler

Scientific challenges in the Arctic: Open water pp. 174-177

Daniel Cressey

A green Arctic pp. 179-180

Lars Kullerud

A peaceful Arctic pp. 180-181

Oran R. Young

The local perspective pp. 182-183

Henry P. Huntington

Bioethics: Brave new biopolitics pp. 184-185

Kevin Finneran

Anthropology: Centuries of skulls pp. 186-186

Alison Abbott

Q&A: Internet visionary pp. 187-187

Jascha Hoffman

Sea-ice minimum is not a one-off pp. 188-188

Christian Melsheimer, Georg Heygster and Justus Notholt

Vaccine research loses out pp. 188-188

Peter Hale, Simon Wain-Hobson and Robin A. Weiss

The JASONs bought into the Vietnam War pp. 188-188

Joseph Schwartz

Fallacy in costs of pollution control pp. 188-188

Neal Hockley

Fruity aphrodisiacs pp. 190-191

Benjamin Prud'homme and Nicolas Gompel

Controlled incandescence pp. 191-192

Jean-Jacques Greffet

Why tumours eat tryptophan pp. 192-194

George C. Prendergast

Sea change for the rise of oxygen pp. 194-195

Timothy W. Lyons and Christopher T. Reinhard

Spins coupled to a persistent current pp. 195-196

Irinel Chiorescu

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor pp. 197-203

Christiane A. Opitz, Ulrike M. Litzenburger, Felix Sahm, Martina Ott, Isabel Tritschler, Saskia Trump, Theresa Schumacher, Leonie Jestaedt, Dieter Schrenk, Michael Weller, Manfred Jugold, Gilles J. Guillemin, Christine L. Miller, Christian Lutz, Bernhard Radlwimmer, Irina Lehmann, Andreas von Deimling, Wolfgang Wick and Michael Platten

Diffraction-unlimited all-optical imaging and writing with a photochromic GFP pp. 204-208

Tim Grotjohann, Ilaria Testa, Marcel Leutenegger, Hannes Bock, Nicolai T. Urban, Flavie Lavoie-Cardinal, Katrin I. Willig, Christian Eggeling, Stefan Jakobs and Stefan W. Hell

DNA stretching by bacterial initiators promotes replication origin opening pp. 209-213

Karl E. Duderstadt, Kevin Chuang and James M. Berger

Low-Mach-number turbulence in interstellar gas revealed by radio polarization gradients pp. 214-217

B. M. Gaensler, M. Haverkorn, B. Burkhart, K. J. Newton–McGee, R. D. Ekers, A. Lazarian, N. M. McClure–Griffiths, T. Robishaw, J. M. Dickey and A. J. Green

Ocean-like water in the Jupiter-family comet 103P/Hartley 2 pp. 218-220

Paul Hartogh, Dariusz C. Lis, Dominique Bockelée-Morvan, Miguel de Val-Borro, Nicolas Biver, Michael Küppers, Martin Emprechtinger, Edwin A. Bergin, Jacques Crovisier, Miriam Rengel, Raphael Moreno, Slawomira Szutowicz and Geoffrey A. Blake

Coherent coupling of a superconducting flux qubit to an electron spin ensemble in diamond pp. 221-224

Xiaobo Zhu, Shiro Saito, Alexander Kemp, Kosuke Kakuyanagi, Shin-ichi Karimoto, Hayato Nakano, William J. Munro, Yasuhiro Tokura, Mark S. Everitt, Kae Nemoto, Makoto Kasu, Norikazu Mizuochi and Kouichi Semba

Self-replication of information-bearing nanoscale patterns pp. 225-228

Tong Wang, Ruojie Sha, Rémi Dreyfus, Mirjam E. Leunissen, Corinna Maass, David J. Pine, Paul M. Chaikin and Nadrian C. Seeman

Atmospheric oxygenation caused by a change in volcanic degassing pressure pp. 229-232

Fabrice Gaillard, Bruno Scaillet and Nicholas T. Arndt

Strong contributors to network persistence are the most vulnerable to extinction pp. 233-235

Serguei Saavedra, Daniel B. Stouffer, Brian Uzzi and Jordi Bascompte

An olfactory receptor for food-derived odours promotes male courtship in Drosophila pp. 236-240

Yael Grosjean, Raphael Rytz, Jean-Pierre Farine, Liliane Abuin, Jérôme Cortot, Gregory S. X. E. Jefferis and Richard Benton

Molecular organization of vomeronasal chemoreception pp. 241-245

Yoh Isogai, Sheng Si, Lorena Pont-Lezica, Taralyn Tan, Vikrant Kapoor, Venkatesh N. Murthy and Catherine Dulac

Theta-paced flickering between place-cell maps in the hippocampus pp. 246-249

Karel Jezek, Espen J. Henriksen, Alessandro Treves, Edvard I. Moser and May-Britt Moser

Peripheral education of the immune system by colonic commensal microbiota pp. 250-254

Stephanie K. Lathrop, Seth M. Bloom, Sindhuja M. Rao, Katherine Nutsch, Chan-Wang Lio, Nicole Santacruz, Daniel A. Peterson, Thaddeus S. Stappenbeck and Chyi-Song Hsieh

A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable pp. 255-259

Hua Tian, Brian Biehs, Søren Warming, Kevin G. Leong, Linda Rangell, Ophir D. Klein and Frederic J. de Sauvage

Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A pp. 260-263

A. J. Ehrlicher, F. Nakamura, J. H. Hartwig, D. A. Weitz and T. P. Stossel

S-nitrosylation of NADPH oxidase regulates cell death in plant immunity pp. 264-268

Byung-Wook Yun, Angela Feechan, Minghui Yin, Noor B. B. Saidi, Thierry Le Bihan, Manda Yu, John W. Moore, Jeong-Gu Kang, Eunjung Kwon, Steven H. Spoel, Jacqueline A. Pallas and Gary J. Loake

Structure of human mitochondrial RNA polymerase pp. 269-273

Rieke Ringel, Marina Sologub, Yaroslav I. Morozov, Dmitry Litonin, Patrick Cramer and Dmitry Temiakov

Erratum: Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration pp. 274-274

Aycan Sentürk, Sylvia Pfennig, Alexander Weiss, Katja Burk and Amparo Acker-Palmer

Erratum: A plastidial sodium-dependent pyruvate transporter pp. 274-274

Tsuyoshi Furumoto, Teppei Yamaguchi, Yumiko Ohshima-Ichie, Masayoshi Nakamura, Yoshiko Tsuchida-Iwata, Masaki Shimamura, Junichi Ohnishi, Shingo Hata, Udo Gowik, Peter Westhoff, Andrea Bräutigam, Andreas P. M. Weber and Katsura Izui

Rookie review pp. 275-277

Virginia Gewin

Complaints department pp. 280-280

Thoraiya Dyer

2011, volume 478, articles 7367

The voice of science: let's agree to disagree pp. 7-7

Daniel Sarewitz

Nobel announcement marred by winner's death pp. 13-14

Ewen Callaway

Stellar performance nets physics prize pp. 14-14

Geoff Brumfiel

Trillion-dollar brain drain pp. 15-15

Kerri Smith

Europe cuts funding red tape pp. 16-16

Natasha Gilbert

Secrets of the human genome disclosed pp. 17-17

Erika Check Hayden

Nature readers flirt with personal genomics pp. 19-19

Brendan Maher

Experts question rankings of journals pp. 20-20

Declan Butler

Human genetics: Genomes on prescription pp. 22-24

Brendan Maher

Science publishing: The trouble with retractions pp. 26-28

Richard Van Noorden

A broken biogeochemical cycle pp. 29-31

James Elser and Elena Bennett

History: Scaling up pp. 32-33

Andrew Robinson

Palaeoanthropology: Craniums with clout pp. 34-34

Henry Gee

Q&A: Speculative realist pp. 35-35

Jascha Hoffman

Reduce drug waste in the environment pp. 36-36

Michael Depledge

Bridging the gender gap in UK science pp. 36-36

Athene Donald, Paul H. Harvey and Angela R. McLean

Cloning advance calls for careful regulation pp. 36-37

Insoo Hyun and Paul Tesar

Energy should form its own discipline pp. 37-37

Sheril R. Kirshenbaum and Michael E. Webber

Giant dam threatens Brazilian rainforest pp. 37-37

Alison G. Nazareno and Thomas E. Lovejoy

Pilot scheme for misconduct database pp. 37-37

Timothée Flutre, Thomas Julou, Livio Riboli-Sasco and Claire Ribrault

Discovery inspires those seeking tenure pp. 37-37

Barbara-Ann Lewis

Triple genomes go far pp. 40-41

George Q. Daley and Jan Helge Solbakk

Homing in on another Earth pp. 41-42

Jacob Bean

Defence against oxidative damage pp. 42-43

Fernando Cruz-Guilloty and Victor L. Perez

Malapa and the genus Homo pp. 44-45

Fred Spoor

Self-aware particles pp. 45-46

Ulrich F. Keyser

A hidden ancestral legacy trumped pp. 46-47

Masayuki Nakamori and Charles Thornton

The gentle cooling touch of light pp. 47-48

Florian Marquardt

Persistence of soil organic matter as an ecosystem property pp. 49-56

Michael W. I. Schmidt, Margaret S. Torn, Samuel Abiven, Thorsten Dittmar, Georg Guggenberger, Ivan A. Janssens, Markus Kleber, Ingrid Kögel-Knabner, Johannes Lehmann, David A. C. Manning, Paolo Nannipieri, Daniel P. Rasse, Steve Weiner and Susan E. Trumbore

Deep sequencing reveals 50 novel genes for recessive cognitive disorders pp. 57-63

Hossein Najmabadi, Hao Hu, Masoud Garshasbi, Tomasz Zemojtel, Seyedeh Sedigheh Abedini, Wei Chen, Masoumeh Hosseini, Farkhondeh Behjati, Stefan Haas, Payman Jamali, Agnes Zecha, Marzieh Mohseni, Lucia Püttmann, Leyla Nouri Vahid, Corinna Jensen, Lia Abbasi Moheb, Melanie Bienek, Farzaneh Larti, Ines Mueller, Robert Weissmann, Hossein Darvish, Klaus Wrogemann, Valeh Hadavi, Bettina Lipkowitz, Sahar Esmaeeli-Nieh, Dagmar Wieczorek, Roxana Kariminejad, Saghar Ghasemi Firouzabadi, Monika Cohen, Zohreh Fattahi, Imma Rost, Faezeh Mojahedi, Christoph Hertzberg, Atefeh Dehghan, Anna Rajab, Mohammad Javad Soltani Banavandi, Julia Hoffer, Masoumeh Falah, Luciana Musante, Vera Kalscheuer, Reinhard Ullmann, Andreas Walter Kuss, Andreas Tzschach, Kimia Kahrizi and H. Hilger Ropers

Frequent pathway mutations of splicing machinery in myelodysplasia pp. 64-69

Kenichi Yoshida, Masashi Sanada, Yuichi Shiraishi, Daniel Nowak, Yasunobu Nagata, Ryo Yamamoto, Yusuke Sato, Aiko Sato-Otsubo, Ayana Kon, Masao Nagasaki, George Chalkidis, Yutaka Suzuki, Masashi Shiosaka, Ryoichiro Kawahata, Tomoyuki Yamaguchi, Makoto Otsu, Naoshi Obara, Mamiko Sakata-Yanagimoto, Ken Ishiyama, Hiraku Mori, Florian Nolte, Wolf-Karsten Hofmann, Shuichi Miyawaki, Sumio Sugano, Claudia Haferlach, H. Phillip Koeffler, Lee-Yung Shih, Torsten Haferlach, Shigeru Chiba, Hiromitsu Nakauchi, Satoru Miyano and Seishi Ogawa

Human oocytes reprogram somatic cells to a pluripotent state pp. 70-75

Scott Noggle, Ho-Lim Fung, Athurva Gore, Hector Martinez, Kathleen Crumm Satriani, Robert Prosser, Kiboong Oum, Daniel Paull, Sarah Druckenmiller, Matthew Freeby, Ellen Greenberg, Kun Zhang, Robin Goland, Mark V. Sauer, Rudolph L. Leibel and Dieter Egli

Complement factor H binds malondialdehyde epitopes and protects from oxidative stress pp. 76-81

David Weismann, Karsten Hartvigsen, Nadine Lauer, Keiryn L. Bennett, Hendrik P. N. Scholl, Peter Charbel Issa, Marisol Cano, Hubert Brandstätter, Sotirios Tsimikas, Christine Skerka, Giulio Superti-Furga, James T. Handa, Peter F. Zipfel, Joseph L. Witztum and Christoph J. Binder

Detectable radio flares following gravitational waves from mergers of binary neutron stars pp. 82-84

Ehud Nakar and Tsvi Piran

Resonances arising from hydrodynamic memory in Brownian motion pp. 85-88

Thomas Franosch, Matthias Grimm, Maxim Belushkin, Flavio M. Mor, Giuseppe Foffi, László Forró and Sylvia Jeney

Laser cooling of a nanomechanical oscillator into its quantum ground state pp. 89-92

Jasper Chan, T. P. Mayer Alegre, Amir H. Safavi-Naeini, Jeff T. Hill, Alex Krause, Simon Gröblacher, Markus Aspelmeyer and Oskar Painter

A carbon isotope challenge to the snowball Earth pp. 93-96

P. Sansjofre, M. Ader, R. I. F. Trindade, M. Elie, J. Lyons, P. Cartigny and A. C. R. Nogueira

Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus pp. 97-102

Sébastien Jacquemont, Alexandre Reymond, Flore Zufferey, Louise Harewood, Robin G. Walters, Zoltán Kutalik, Danielle Martinet, Yiping Shen, Armand Valsesia, Noam D. Beckmann, Gudmar Thorleifsson, Marco Belfiore, Sonia Bouquillon, Dominique Campion, Nicole de Leeuw, Bert B. A. de Vries, Tõnu Esko, Bridget A. Fernandez, Fernando Fernández-Aranda, José Manuel Fernández-Real, Mònica Gratacòs, Audrey Guilmatre, Juliane Hoyer, Marjo-Riitta Jarvelin, R. Frank Kooy, Ants Kurg, Cédric Le Caignec, Katrin Männik, Orah S. Platt, Damien Sanlaville, Mieke M. Van Haelst, Sergi Villatoro Gomez, Faida Walha, Bai-lin Wu, Yongguo Yu, Azzedine Aboura, Marie-Claude Addor, Yves Alembik, Stylianos E. Antonarakis, Benoît Arveiler, Magalie Barth, Nathalie Bednarek, Frédérique Béna, Sven Bergmann, Mylène Beri, Laura Bernardini, Bettina Blaumeiser, Dominique Bonneau, Armand Bottani, Odile Boute, Han G. Brunner, Dorothée Cailley, Patrick Callier, Jean Chiesa, Jacqueline Chrast, Lachlan Coin, Charles Coutton, Jean-Marie Cuisset, Jean-Christophe Cuvellier, Albert David, Bénédicte de Freminville, Bruno Delobel, Marie-Ange Delrue, Bénédicte Demeer, Dominique Descamps, Gérard Didelot, Klaus Dieterich, Vittoria Disciglio, Martine Doco-Fenzy, Séverine Drunat, Bénédicte Duban-Bedu, Christèle Dubourg, Julia S. El-Sayed Moustafa, Paul Elliott, Brigitte H. W. Faas, Laurence Faivre, Anne Faudet, Florence Fellmann, Alessandra Ferrarini, Richard Fisher, Elisabeth Flori, Lukas Forer, Dominique Gaillard, Marion Gerard, Christian Gieger, Stefania Gimelli, Giorgio Gimelli, Hans J. Grabe, Agnès Guichet, Olivier Guillin, Anna-Liisa Hartikainen, Délphine Heron, Loyse Hippolyte, Muriel Holder, Georg Homuth, Bertrand Isidor, Sylvie Jaillard, Zdenek Jaros, Susana Jiménez-Murcia, Géraldine Joly Helas, Philippe Jonveaux, Satu Kaksonen, Boris Keren, Anita Kloss-Brandstätter, Nine V. A. M. Knoers, David A. Koolen, Peter M. Kroisel, Florian Kronenberg, Audrey Labalme, Emilie Landais, Elisabetta Lapi, Valérie Layet, Solenn Legallic, Bruno Leheup, Barbara Leube, Suzanne Lewis, Josette Lucas, Kay D. MacDermot, Pall Magnusson, Christian Marshall, Michèle Mathieu-Dramard, Mark I. McCarthy, Thomas Meitinger, Maria Antonietta Mencarelli, Giuseppe Merla, Alexandre Moerman, Vincent Mooser, Fanny Morice-Picard, Mafalda Mucciolo, Matthias Nauck, Ndeye Coumba Ndiaye, Ann Nordgren, Laurent Pasquier, Florence Petit, Rolph Pfundt, Ghislaine Plessis, Evica Rajcan-Separovic, Gian Paolo Ramelli, Anita Rauch, Roberto Ravazzolo, Andre Reis, Alessandra Renieri, Cristobal Richart, Janina S. Ried, Claudine Rieubland, Wendy Roberts, Katharina M. Roetzer, Caroline Rooryck, Massimiliano Rossi, Evald Saemundsen, Véronique Satre, Claudia Schurmann, Engilbert Sigurdsson, Dimitri J. Stavropoulos, Hreinn Stefansson, Carola Tengström, Unnur Thorsteinsdóttir, Francisco J. Tinahones, Renaud Touraine, Louis Vallée, Ellen van Binsbergen, Nathalie Van der Aa, Catherine Vincent-Delorme, Sophie Visvikis-Siest, Peter Vollenweider, Henry Völzke, Anneke T. Vulto- van Silfhout, Gérard Waeber, Carina Wallgren-Pettersson, Robert M. Witwicki, Simon Zwolinksi, Joris Andrieux, Xavier Estivill, James F. Gusella, Omar Gustafsson, Andres Metspalu, Stephen W. Scherer, Kari Stefansson, Alexandra I. F. Blakemore, Jacques S. Beckmann and Philippe Froguel

Dynamics of human adipose lipid turnover in health and metabolic disease pp. 110-113

Peter Arner, Samuel Bernard, Mehran Salehpour, Göran Possnert, Jakob Liebl, Peter Steier, Bruce A. Buchholz, Mats Eriksson, Erik Arner, Hans Hauner, Thomas Skurk, Mikael Rydén, Keith N. Frayn and Kirsty L. Spalding

Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function pp. 114-118

Chris McDermott-Roe, Junmei Ye, Rizwan Ahmed, Xi-Ming Sun, Anna Serafín, James Ware, Leonardo Bottolo, Phil Muckett, Xavier Cañas, Jisheng Zhang, Glenn C. Rowe, Rachel Buchan, Han Lu, Adam Braithwaite, Massimiliano Mancini, David Hauton, Ramon Martí, Elena García-Arumí, Norbert Hubner, Howard Jacob, Tadao Serikawa, Vaclav Zidek, Frantisek Papousek, Frantisek Kolar, Maria Cardona, Marisol Ruiz-Meana, David García-Dorado, Joan X. Comella, Leanne E. Felkin, Paul J. R. Barton, Zoltan Arany, Michal Pravenec, Enrico Petretto, Daniel Sanchis and Stuart A. Cook

Control of flowering and storage organ formation in potato by FLOWERING LOCUS T pp. 119-122

Cristina Navarro, José A. Abelenda, Eduard Cruz-Oró, Carlos A. Cuéllar, Shojiro Tamaki, Javier Silva, Ko Shimamoto and Salomé Prat

Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model pp. 123-126

Yimin Hua, Kentaro Sahashi, Frank Rigo, Gene Hung, Guy Horev, C. Frank Bennett and Adrian R. Krainer

Pathogenic exon-trapping by SVA retrotransposon and rescue in Fukuyama muscular dystrophy pp. 127-131

Mariko Taniguchi-Ikeda, Kazuhiro Kobayashi, Motoi Kanagawa, Chih-chieh Yu, Kouhei Mori, Tetsuya Oda, Atsushi Kuga, Hiroki Kurahashi, Hasan O. Akman, Salvatore DiMauro, Ryuji Kaji, Toshifumi Yokota, Shin’ichi Takeda and Tatsushi Toda

ATP-induced helicase slippage reveals highly coordinated subunits pp. 132-135

Bo Sun, Daniel S. Johnson, Gayatri Patel, Benjamin Y. Smith, Manjula Pandey, Smita S. Patel and Michelle D. Wang

Erratum: Detection of prokaryotic mRNA signifies microbial viability and promotes immunity pp. 136-136

Leif E. Sander, Michael J. Davis, Mark V. Boekschoten, Derk Amsen, Christopher C. Dascher, Bernard Ryffel, Joel A. Swanson, Michael Müller and J. Magarian Blander

Bright light, better labels pp. 137-142

Monya Baker

Education: Inspiration for informatics pp. 143-145

Virginia Gewin

The human touch pp. 145-145

Lydia Soraya Murray

Here be monsters pp. 148-148

Stephanie Zvan