Antibiotic treatment expands the resistance reservoir and ecological network of the phage metagenome

Sheetal R. Modi, Henry H. Lee, Catherine S. Spina and James J. Collins ()
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Sheetal R. Modi: Howard Hughes Medical Institute, and Center for BioDynamics, Boston University
Henry H. Lee: Howard Hughes Medical Institute, and Center for BioDynamics, Boston University
Catherine S. Spina: Howard Hughes Medical Institute, and Center for BioDynamics, Boston University
James J. Collins: Howard Hughes Medical Institute, and Center for BioDynamics, Boston University

Nature, 2013, vol. 499, issue 7457, 219-222

Abstract: By exploring the phageome in mice, antibiotic treatment is shown to lead to enrichment of phage-encoded genes that are related to antibiotic resistance.

Date: 2013
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DOI: 10.1038/nature12212

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