Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate

York Posor, Marielle Eichhorn-Gruenig, Dmytro Puchkov, Johannes Schöneberg, Alexander Ullrich, André Lampe, Rainer Müller, Sirus Zarbakhsh, Federico Gulluni, Emilio Hirsch, Michael Krauss, Carsten Schultz, Jan Schmoranzer, Frank Noé and Volker Haucke ()
Additional contact information
York Posor: Leibniz Institut für Molekulare Pharmakologie (FMP) & Freie Universität Berlin, Robert-Roessle-Straße 10, 13125 Berlin, Germany
Marielle Eichhorn-Gruenig: Leibniz Institut für Molekulare Pharmakologie (FMP) & Freie Universität Berlin, Robert-Roessle-Straße 10, 13125 Berlin, Germany
Dmytro Puchkov: Leibniz Institut für Molekulare Pharmakologie (FMP) & Freie Universität Berlin, Robert-Roessle-Straße 10, 13125 Berlin, Germany
Johannes Schöneberg: Freie Universität Berlin, DFG Research Center MATHEON, Arnimallee 6, 14195 Berlin, Germany
Alexander Ullrich: Freie Universität Berlin, DFG Research Center MATHEON, Arnimallee 6, 14195 Berlin, Germany
André Lampe: Leibniz Institut für Molekulare Pharmakologie (FMP) & Freie Universität Berlin, Robert-Roessle-Straße 10, 13125 Berlin, Germany
Rainer Müller: European Molecular Biology Laboratory (EMBL), Cell Biology and Biophysics Unit, 69117 Heidelberg, Germany
Sirus Zarbakhsh: European Molecular Biology Laboratory (EMBL), Cell Biology and Biophysics Unit, 69117 Heidelberg, Germany
Federico Gulluni: Molecular Biotechnology Center, Biology and Biochemistry, University of Torino, Via Nizza 52, 10126 Torino, Italy
Emilio Hirsch: Molecular Biotechnology Center, Biology and Biochemistry, University of Torino, Via Nizza 52, 10126 Torino, Italy
Michael Krauss: Leibniz Institut für Molekulare Pharmakologie (FMP) & Freie Universität Berlin, Robert-Roessle-Straße 10, 13125 Berlin, Germany
Carsten Schultz: European Molecular Biology Laboratory (EMBL), Cell Biology and Biophysics Unit, 69117 Heidelberg, Germany
Jan Schmoranzer: Leibniz Institut für Molekulare Pharmakologie (FMP) & Freie Universität Berlin, Robert-Roessle-Straße 10, 13125 Berlin, Germany
Frank Noé: Freie Universität Berlin, DFG Research Center MATHEON, Arnimallee 6, 14195 Berlin, Germany
Volker Haucke: Leibniz Institut für Molekulare Pharmakologie (FMP) & Freie Universität Berlin, Robert-Roessle-Straße 10, 13125 Berlin, Germany

Nature, 2013, vol. 499, issue 7457, 233-237

Abstract: Phosphoinositides are important regulators of intracellular membrane traffic, and although the role of PI(4,5)P2 has been well characterised, the function of PI(3,4)P2 remains unclear; here the formation of PI(3,4)P2 by the class II phosphatidylinositol-3-kinase C2α enzyme is shown to control clathrin-mediated endocytosis.

Date: 2013
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/nature12360 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:499:y:2013:i:7457:d:10.1038_nature12360

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature12360

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().