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2012, volume 491, articles 7426

Causes of an ad 774–775 14C increase pp. E1-E2

Adrian L. Melott and Brian C. Thomas

Science should be ready to jump off ‘the cliff’ pp. 639-639

Colin Macilwain

Space budget blow to climate science pp. 645-646

Edwin Cartlidge

Growth of ethanol fuel stalls in Brazil pp. 646-647

Claudio Angelo

Daily dose of toxics to be tracked pp. 647-647

Ewen Callaway

Funding protest hits Bulgarian research agency pp. 649-649

Alison Abbott

Microsatellites aim to fill weather-data gap pp. 650-651

Eric Hand

The global energy challenge: Awash with carbon pp. 654-655

Jeff Tollefson and Richard Monastersky

The Kyoto Protocol: Hot air pp. 656-658

Quirin Schiermeier

Adapting to a warmer world: No going back pp. 659-661

Olive Heffernan

The Kyoto approach has failed pp. 663-665

Dieter Helm

Cap and trade finds new energy pp. 666-667

Michael Grubb

Engineering: Turbulent genius pp. 668-669

Allan McRobie

History: Dreaming of the bomb pp. 670-670

Istvan Hargittai

Thanatology: Beyond the grave pp. 671-671

Ewen Callaway

Lichens under threat from ash dieback pp. 672-672

Christopher J. Ellis, Brian J. Coppins and Peter M. Hollingsworth

NIH chimps: don't sell sanctuary short pp. 672-672

Theodora Capaldo

NIH chimps: use existing facilities pp. 672-672

John L. VandeBerg

NIH chimps: Texas lab is not a sanctuary pp. 672-672

John Pippin

Cuts endanger young scientists in Europe pp. 672-672

Christian Broberger and Anna Sjöström Douagi

Substitution with vision pp. 674-675

Gus L. W. Hart

Forests on the brink pp. 675-676

Bettina M. J. Engelbrecht

Magma chambers on a slow burner pp. 677-678

Albrecht W. Hofmann

Decoding our daily bread pp. 678-680

Peter Langridge

Vitamins prime immunity pp. 680-681

Wei-Jen Chua and Ted H. Hansen

Strongly correlated transport pp. 681-682

Lincoln D. Carr and Mark T. Lusk

The mystery of recent stratospheric temperature trends pp. 692-697

David W. J. Thompson, Dian J. Seidel, William J. Randel, Cheng-Zhi Zou, Amy H. Butler, Carl Mears, Albert Osso, Craig Long and Roger Lin

The global pattern of trace-element distributions in ocean floor basalts pp. 698-704

Hugh St C. O’Neill and Frances E. Jenner

Analysis of the bread wheat genome using whole-genome shotgun sequencing pp. 705-710

Rachel Brenchley, Manuel Spannagl, Matthias Pfeifer, Gary L. A. Barker, Rosalinda D’Amore, Alexandra M. Allen, Neil McKenzie, Melissa Kramer, Arnaud Kerhornou, Dan Bolser, Suzanne Kay, Darren Waite, Martin Trick, Ian Bancroft, Yong Gu, Naxin Huo, Ming-Cheng Luo, Sunish Sehgal, Bikram Gill, Sharyar Kianian, Olin Anderson, Paul Kersey, Jan Dvorak, W. Richard McCombie, Anthony Hall, Klaus F. X. Mayer, Keith J. Edwards, Michael W. Bevan and Neil Hall

MR1 presents microbial vitamin B metabolites to MAIT cells pp. 717-723

Lars Kjer-Nielsen, Onisha Patel, Alexandra J. Corbett, Jérôme Le Nours, Bronwyn Meehan, Ligong Liu, Mugdha Bhati, Zhenjun Chen, Lyudmila Kostenko, Rangsima Reantragoon, Nicholas A. Williamson, Anthony W. Purcell, Nadine L. Dudek, Malcolm J. McConville, Richard A. J. O’Hair, George N. Khairallah, Dale I. Godfrey, David P. Fairlie, Jamie Rossjohn and James McCluskey

Visualizing transient low-populated structures of RNA pp. 724-728

Elizabeth A. Dethoff, Katja Petzold, Jeetender Chugh, Anette Casiano-Negroni and Hashim M. Al-Hashimi

An over-massive black hole in the compact lenticular galaxy NGC 1277 pp. 729-731

Remco C. E. van den Bosch, Karl Gebhardt, Kayhan Gültekin, Glenn van de Ven, Arjen van der Wel and Jonelle L. Walsh

Active upper-atmosphere chemistry and dynamics from polar circulation reversal on Titan pp. 732-735

Nicholas A. Teanby, Patrick G. J. Irwin, Conor A. Nixon, Remco de Kok, Sandrine Vinatier, Athena Coustenis, Elliot Sefton-Nash, Simon B. Calcutt and F. Michael Flasar

Observing the drop of resistance in the flow of a superfluid Fermi gas pp. 736-739

David Stadler, Sebastian Krinner, Jakob Meineke, Jean-Philippe Brantut and Tilman Esslinger

A canonical stability–elasticity relationship verified for one million face-centred-cubic structures pp. 740-743

Sascha B. Maisel, Michaela Höfler and Stefan Müller

Rapid coupling between ice volume and polar temperature over the past 150,000 years pp. 744-747

K. M. Grant, E. J. Rohling, M. Bar-Matthews, A. Ayalon, M. Medina-Elizalde, C. Bronk Ramsey, C. Satow and A. P. Roberts

Development of teeth and jaws in the earliest jawed vertebrates pp. 748-751

Martin Rücklin, Philip C. J. Donoghue, Zerina Johanson, Kate Trinajstic, Federica Marone and Marco Stampanoni

Global convergence in the vulnerability of forests to drought pp. 752-755

Brendan Choat, Steven Jansen, Tim J. Brodribb, Hervé Cochard, Sylvain Delzon, Radika Bhaskar, Sandra J. Bucci, Taylor S. Feild, Sean M. Gleason, Uwe G. Hacke, Anna L. Jacobsen, Frederic Lens, Hafiz Maherali, Jordi Martínez-Vilalta, Stefan Mayr, Maurizio Mencuccini, Patrick J. Mitchell, Andrea Nardini, Jarmila Pittermann, R. Brandon Pratt, John S. Sperry, Mark Westoby, Ian J. Wright and Amy E. Zanne

The genomic landscape of species divergence in Ficedula flycatchers pp. 756-760

Hans Ellegren, Linnéa Smeds, Reto Burri, Pall I. Olason, Niclas Backström, Takeshi Kawakami, Axel Künstner, Hannu Mäkinen, Krystyna Nadachowska-Brzyska, Anna Qvarnström, Severin Uebbing and Jochen B. W. Wolf

A map of visual space in the primate entorhinal cortex pp. 761-764

Nathaniel J. Killian, Michael J. Jutras and Elizabeth A. Buffalo

Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme pp. 765-768

Julie B. Sneddon, Malgorzata Borowiak and Douglas A. Melton

Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells pp. 769-773

Fabien G. Lafaille, Itai M. Pessach, Shen-Ying Zhang, Michael J. Ciancanelli, Melina Herman, Avinash Abhyankar, Shui-Wang Ying, Sotirios Keros, Peter A. Goldstein, Gustavo Mostoslavsky, Jose Ordovas-Montanes, Emmanuelle Jouanguy, Sabine Plancoulaine, Edmund Tu, Yechiel Elkabetz, Saleh Al-Muhsen, Marc Tardieu, Thorsten M. Schlaeger, George Q. Daley, Laurent Abel, Jean-Laurent Casanova, Lorenz Studer and Luigi D. Notarangelo

Resurrection of endogenous retroviruses in antibody-deficient mice pp. 774-778

George R. Young, Urszula Eksmond, Rosalba Salcedo, Lena Alexopoulou, Jonathan P. Stoye and George Kassiotis

Structure of the chemokine receptor CXCR1 in phospholipid bilayers pp. 779-783

Sang Ho Park, Bibhuti B. Das, Fabio Casagrande, Ye Tian, Henry J. Nothnagel, Mignon Chu, Hans Kiefer, Klaus Maier, Anna A. De Angelis, Francesca M. Marassi and Stanley J. Opella

Correction: Corrigendum: Yeretssian et al. reply pp. 784-784

Garabet Yeretssian, Ricardo G. Correa, Karine Doiron, Patrick Fitzgerald, Christopher P. Dillon, Douglas R. Green, John C. Reed and Maya Saleh

Correction: Corrigendum: CD95 promotes tumour growth pp. 784-784

Lina Chen, Sun-Mi Park, Alexei V. Tumanov, Annika Hau, Kenjiro Sawada, Christine Feig, Jerrold R. Turner, Yang-Xin Fu, Iris L. Romero, Ernst Lengyel and Marcus E. Peter

Column: When lab leaders take too much control pp. 785-786

Charles Wood

Turning point: Sarah Aciego pp. 787-787

Virginia Gewin

Transmission received pp. 790-790

Peter J. Enyeart

2012, volume 491, articles 7425

Physical scientists take on cancer pp. S49-S49

Lauren Gravitz

Oncology: Getting physical pp. S50-S51

Jennie Dusheck

Megadata: The odd couple pp. S52-S54

Erik Vance

Perspective: Finding cancer's first principles pp. S55-S55

Robert Gatenby

Mechanics: The forces of cancer pp. S56-S57

Erika Jonietz

Nanotechnology: Carrying drugs pp. S58-S60

Katherine Bourzac

Perspective: Meeting of minds pp. S61-S61

David Agus and Murray Gell-Mann

Modelling: Computing cancer pp. S62-S63

Neil Savage

Diagnostics: Playing detective pp. S64-S65

Cassandra Willyard

Mathematical modelling: Forecasting cancer pp. S66-S67

Katharine Gammon

How resilient is your country? pp. 497-497

Erwann Michel-Kerjan

Drug-pollution law all washed up pp. 503-504

Natasha Gilbert

Truant particles turn the screw on supersymmetry pp. 505-506

Matthew Chalmers

Hunt for life under Antarctic ice heats up pp. 506-507

Quirin Schiermeier

Fresh start for global disease fund pp. 508-508

Declan Butler

Lab astrophysics aims for the stars pp. 509-509

Eugenie Samuel Reich

Private labs caught in budget crunch pp. 510-510

Heidi Ledford

The science of cities: Life in the concrete jungle pp. 514-515

Courtney Humphries

Chemical biology: DNA's new alphabet pp. 516-518

Roberta Kwok

Make nanotechnology research open-source pp. 519-521

Joshua Pearce

Let US physics commit to collaboration pp. 522-522

Barry Barish

Philosophy: Creative resilience pp. 523-523

Michael Shermer

In Retrospect: The Origin of Life pp. 524-525

Tony Hyman and Cliff Brangwynne

Anatomy: The bird stripped bare pp. 526-526

Alison Abbott

Flood defence for financial hubs pp. 527-527

James H. Vance

Tightening up on tree carbon estimates pp. 527-527

Rosa C. Goodman, Oliver L. Phillips and Timothy R. Baker

Global science can bolster diplomacy pp. 527-527

Lindsay Chura

Medicalization of sleep may be needed pp. 527-527

Sam Fleishman

Real skin shedding meets mythology pp. 527-527

Andrew C. Walls, Vanessa E. Johnson and Scott A. Norton

Synchronized tumbling particles pp. 530-531

Sabine H. L. Klapp

Sharpening the mind pp. 531-532

Sally McBrearty

Water's response to the fear of water pp. 533-535

Huib J. Bakker

Stem cells bear eggs pp. 535-536

Sihem Cheloufi and Konrad Hochedlinger

Depression brought to light pp. 537-538

Lisa M. Monteggia and Ege T. Kavalali

A piece of the methane puzzle pp. 538-539

Samantha B. Joye

A chilling effect for molecules pp. 539-540

John F. Barry and David DeMille

Zero-valent sulphur is a key intermediate in marine methane oxidation pp. 541-546

Jana Milucka, Timothy G. Ferdelman, Lubos Polerecky, Daniela Franzke, Gunter Wegener, Markus Schmid, Ingo Lieberwirth, Michael Wagner, Friedrich Widdel and Marcel M. M. Kuypers

Hippocampal–cortical interaction during periods of subcortical silence pp. 547-553

N. K. Logothetis, O. Eschenko, Y. Murayama, M. Augath, T. Steudel, H. C. Evrard, M. Besserve and A. Oeltermann

Novel Foxo1-dependent transcriptional programs control Treg cell function pp. 554-559

Weiming Ouyang, Will Liao, Chong T. Luo, Na Yin, Morgan Huse, Myoungjoo V. Kim, Min Peng, Pamela Chan, Qian Ma, Yifan Mo, Dies Meijer, Keji Zhao, Alexander Y. Rudensky, Gurinder Atwal, Michael Q. Zhang and Ming O. Li

DAXX envelops a histone H3.3–H4 dimer for H3.3-specific recognition pp. 560-565

Simon J. Elsässer, Hongda Huang, Peter W. Lewis, Jason W. Chin, C. David Allis and Dinshaw J. Patel

Albedo and atmospheric constraints of dwarf planet Makemake from a stellar occultation pp. 566-569

J. L. Ortiz, B. Sicardy, F. Braga-Ribas, A. Alvarez-Candal, E. Lellouch, R. Duffard, N. Pinilla-Alonso, V. D. Ivanov, S. P. Littlefair, J. I. B. Camargo, M. Assafin, E. Unda-Sanzana, E. Jehin, N. Morales, G. Tancredi, R. Gil-Hutton, I. de la Cueva, J. P. Colque, D. N. Da Silva Neto, J. Manfroid, A. Thirouin, P. J. Gutiérrez, J. Lecacheux, M. Gillon, A. Maury, F. Colas, J. Licandro, T. Mueller, C. Jacques, D. Weaver, A. Milone, R. Salvo, S. Bruzzone, F. Organero, R. Behrend, S. Roland, R. Vieira-Martins, T. Widemann, F. Roques, P. Santos-Sanz, D. Hestroffer, V. S. Dhillon, T. R. Marsh, C. Harlingten, A. Campo Bagatin, M. L. Alonso, M. Ortiz, C. Colazo, H. J. F. Lima, A. S. Oliveira, L. O. Kerber, R. Smiljanic, E. Pimentel, B. Giacchini, P. Cacella and M. Emilio

Sisyphus cooling of electrically trapped polyatomic molecules pp. 570-573

Martin Zeppenfeld, Barbara G. U. Englert, Rosa Glöckner, Alexander Prehn, Manuel Mielenz, Christian Sommer, Laurens D. van Buuren, Michael Motsch and Gerhard Rempe

Revealing the quantum regime in tunnelling plasmonics pp. 574-577

Kevin J. Savage, Matthew M. Hawkeye, Rubén Esteban, Andrei G. Borisov, Javier Aizpurua and Jeremy J. Baumberg

Linking synchronization to self-assembly using magnetic Janus colloids pp. 578-581

Jing Yan, Moses Bloom, Sung Chul Bae, Erik Luijten and Steve Granick

Water structural transformation at molecular hydrophobic interfaces pp. 582-585

Joel G. Davis, Kamil P. Gierszal, Ping Wang and Dor Ben-Amotz

Lower satellite-gravimetry estimates of Antarctic sea-level contribution pp. 586-589

Matt A. King, Rory J. Bingham, Phil Moore, Pippa L. Whitehouse, Michael J. Bentley and Glenn A. Milne

An early and enduring advanced technology originating 71,000 years ago in South Africa pp. 590-593

Kyle S. Brown, Curtis W. Marean, Zenobia Jacobs, Benjamin J. Schoville, Simen Oestmo, Erich C. Fisher, Jocelyn Bernatchez, Panagiotis Karkanas and Thalassa Matthews

Aberrant light directly impairs mood and learning through melanopsin-expressing neurons pp. 594-598

Tara A. LeGates, Cara M. Altimus, Hui Wang, Hey-Kyoung Lee, Sunggu Yang, Haiqing Zhao, Alfredo Kirkwood, E. Todd Weber and Samer Hattar

Synaptic amplification by dendritic spines enhances input cooperativity pp. 599-602

Mark T. Harnett, Judit K. Makara, Nelson Spruston, William L. Kath and Jeffrey C. Magee

Progressive degeneration of human neural stem cells caused by pathogenic LRRK2 pp. 603-607

Guang-Hui Liu, Jing Qu, Keiichiro Suzuki, Emmanuel Nivet, Mo Li, Nuria Montserrat, Fei Yi, Xiuling Xu, Sergio Ruiz, Weiqi Zhang, Ulrich Wagner, Audrey Kim, Bing Ren, Ying Li, April Goebl, Jessica Kim, Rupa Devi Soligalla, Ilir Dubova, James Thompson, John Yates, Concepcion Rodriguez Esteban, Ignacio Sancho-Martinez and Juan Carlos Izpisua Belmonte

Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts pp. 608-612

Dhvanit I. Shah, Naoko Takahashi-Makise, Jeffrey D. Cooney, Liangtao Li, Iman J. Schultz, Eric L. Pierce, Anupama Narla, Alexandra Seguin, Shilpa M. Hattangadi, Amy E. Medlock, Nathaniel B. Langer, Tamara A. Dailey, Slater N. Hurst, Danilo Faccenda, Jessica M. Wiwczar, Spencer K. Heggers, Guillaume Vogin, Wen Chen, Caiyong Chen, Dean R. Campagna, Carlo Brugnara, Yi Zhou, Benjamin L. Ebert, Nika N. Danial, Mark D. Fleming, Diane M. Ward, Michelangelo Campanella, Harry A. Dailey, Jerry Kaplan and Barry H. Paw

Accelerated disassembly of IgE–receptor complexes by a disruptive macromolecular inhibitor pp. 613-617

Beomkyu Kim, Alexander Eggel, Svetlana S. Tarchevskaya, Monique Vogel, Heino Prinz and Theodore S. Jardetzky

BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs pp. 618-621

Rebecca Mathew, Michael P. Seiler, Seth T. Scanlon, Ai-ping Mao, Michael G. Constantinides, Clara Bertozzi-Villa, Jeffrey D. Singer and Albert Bendelac

Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter pp. 622-626

Romina Mancusso, G. Glenn Gregorio, Qun Liu and Da-Neng Wang

Academia: Off the tenured track pp. 627-629

Kendall Powell

Expatriate scientists get organized pp. 629-629

Michele Catanzaro

Goliath falls pp. 632-632

Taik Hobson

2012, volume 491, articles 7424

Be persuasive. Be brave. Be arrested (if necessary) pp. 303-303

Jeremy Grantham

Obama reasserts research focus pp. 309-311

Eric Hand, Ivan Semeniuk, Jeff Tollefson and Meredith Wadman

Snow survey hopes for avalanche of data pp. 312-313

Jane Qiu

Chelation-therapy heart trial draws fire pp. 313-315

Ewen Callaway

Pig geneticists go the whole hog pp. 315-316

Alison Abbott

Investment relief for biotech sector pp. 316-316

Heidi Ledford

Berlin aims to create research powerhouse pp. 317-317

Quirin Schiermeier

Reproductive biology: Fertile mind pp. 318-320

Trisha Gura

Simulation: Quantum leaps pp. 322-324

Geoff Brumfiel

Secure the Internet pp. 325-326

Ben Laurie and Cory Doctorow

Bring more rigour to GM research pp. 327-327

François Houllier

Conservation: Shoring up the wonders pp. 328-329

Alison Abbott

Science fiction: Curtains for space opera? pp. 330-331

Leigh Phillips

Computer science: Virtually there pp. 331-331

John Gilbey

Standardize the diet for zebrafish model pp. 333-333

Sam Penglase, Mari Moren and Kristin Hamre

Clean stoves already in use in rural India pp. 333-333

Sudhir Kumar

Union improves postdocs' rights pp. 333-333

Neal Sweeney

Biomedical network in South America pp. 333-333

Eduardo Arzt

Environmental stress seen since antiquity pp. 333-333

Frank Vereecken

Edward Donnall Thomas (1920–2012) pp. 334-334

Rainer Storb

Birds of a feather pp. 336-337

Robert E. Ricklefs and Mark Pagel

Historical drought trends revisited pp. 338-339

Sonia I. Seneviratne

Spontaneous flows and self-propelled drops pp. 340-341

M. Cristina Marchetti

Personality in the wild pp. 341-342

Alison M. Bell

Complexion matters pp. 342-343

Mizuho Fukunaga-Kalabis and Meenhard Herlyn

Putting a spin on photon entanglement pp. 343-344

Sophia E. Economou

Nitric oxide caught in traffic pp. 344-345

Mark T. Gladwin and Daniel B. Kim-Shapiro

Metabolism and disease pp. 347-347

Joshua Finkelstein, Noah Gray, Marie Thérèse Heemels, Barbara Marte and Deepa Nath

Circadian topology of metabolism pp. 348-356

Joseph Bass

Central nervous system control of metabolism pp. 357-363

Martin G. Myers and David P. Olson

How cancer metabolism is tuned for proliferation and vulnerable to disruption pp. 364-373

Almut Schulze and Adrian L. Harris

Mitochondrial disorders as windows into an ancient organelle pp. 374-383

Scott B. Vafai and Vamsi K. Mootha

Metabolic phenotyping in clinical and surgical environments pp. 384-392

Jeremy K. Nicholson, Elaine Holmes, James M. Kinross, Ara W. Darzi, Zoltan Takats and John C. Lindon

Analyses of pig genomes provide insight into porcine demography and evolution pp. 393-398

Martien A. M. Groenen, Alan L. Archibald, Hirohide Uenishi, Christopher K. Tuggle, Yasuhiro Takeuchi, Max F. Rothschild, Claire Rogel-Gaillard, Chankyu Park, Denis Milan, Hendrik-Jan Megens, Shengting Li, Denis M. Larkin, Heebal Kim, Laurent A. F. Frantz, Mario Caccamo, Hyeonju Ahn, Bronwen L. Aken, Anna Anselmo, Christian Anthon, Loretta Auvil, Bouabid Badaoui, Craig W. Beattie, Christian Bendixen, Daniel Berman, Frank Blecha, Jonas Blomberg, Lars Bolund, Mirte Bosse, Sara Botti, Zhan Bujie, Megan Bystrom, Boris Capitanu, Denise Carvalho-Silva, Patrick Chardon, Celine Chen, Ryan Cheng, Sang-Haeng Choi, William Chow, Richard C. Clark, Christopher Clee, Richard P. M. A. Crooijmans, Harry D. Dawson, Patrice Dehais, Fioravante De Sapio, Bert Dibbits, Nizar Drou, Zhi-Qiang Du, Kellye Eversole, João Fadista, Susan Fairley, Thomas Faraut, Geoffrey J. Faulkner, Katie E. Fowler, Merete Fredholm, Eric Fritz, James G. R. Gilbert, Elisabetta Giuffra, Jan Gorodkin, Darren K. Griffin, Jennifer L. Harrow, Alexander Hayward, Kerstin Howe, Zhi-Liang Hu, Sean J. Humphray, Toby Hunt, Henrik Hornshøj, Jin-Tae Jeon, Patric Jern, Matthew Jones, Jerzy Jurka, Hiroyuki Kanamori, Ronan Kapetanovic, Jaebum Kim, Jae-Hwan Kim, Kyu-Won Kim, Tae-Hun Kim, Greger Larson, Kyooyeol Lee, Kyung-Tai Lee, Richard Leggett, Harris A. Lewin, Yingrui Li, Wansheng Liu, Jane E. Loveland, Yao Lu, Joan K. Lunney, Jian Ma, Ole Madsen, Katherine Mann, Lucy Matthews, Stuart McLaren, Takeya Morozumi, Michael P. Murtaugh, Jitendra Narayan, Dinh Truong Nguyen, Peixiang Ni, Song-Jung Oh, Suneel Onteru, Frank Panitz, Eung-Woo Park, Hong-Seog Park, Geraldine Pascal, Yogesh Paudel, Miguel Perez-Enciso, Ricardo Ramirez-Gonzalez, James M. Reecy, Sandra Rodriguez-Zas, Gary A. Rohrer, Lauretta Rund, Yongming Sang, Kyle Schachtschneider, Joshua G. Schraiber, John Schwartz, Linda Scobie, Carol Scott, Stephen Searle, Bertrand Servin, Bruce R. Southey, Goran Sperber, Peter Stadler, Jonathan V. Sweedler, Hakim Tafer, Bo Thomsen, Rashmi Wali, Jian Wang, Jun Wang, Simon White, Xun Xu, Martine Yerle, Guojie Zhang, Jianguo Zhang, Jie Zhang, Shuhong Zhao, Jane Rogers, Carol Churcher and Lawrence B. Schook

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes pp. 399-405

Andrew V. Biankin, Nicola Waddell, Karin S. Kassahn, Marie-Claude Gingras, Lakshmi B. Muthuswamy, Amber L. Johns, David K. Miller, Peter J. Wilson, Ann-Marie Patch, Jianmin Wu, David K. Chang, Mark J. Cowley, Brooke B. Gardiner, Sarah Song, Ivon Harliwong, Senel Idrisoglu, Craig Nourse, Ehsan Nourbakhsh, Suzanne Manning, Shivangi Wani, Milena Gongora, Marina Pajic, Christopher J. Scarlett, Anthony J. Gill, Andreia V. Pinho, Ilse Rooman, Matthew Anderson, Oliver Holmes, Conrad Leonard, Darrin Taylor, Scott Wood, Qinying Xu, Katia Nones, J. Lynn Fink, Angelika Christ, Tim Bruxner, Nicole Cloonan, Gabriel Kolle, Felicity Newell, Mark Pinese, R. Scott Mead, Jeremy L. Humphris, Warren Kaplan, Marc D. Jones, Emily K. Colvin, Adnan M. Nagrial, Emily S. Humphrey, Angela Chou, Venessa T. Chin, Lorraine A. Chantrill, Amanda Mawson, Jaswinder S. Samra, James G. Kench, Jessica A. Lovell, Roger J. Daly, Neil D. Merrett, Christopher Toon, Krishna Epari, Nam Q. Nguyen, Andrew Barbour, Nikolajs Zeps, Nipun Kakkar, Fengmei Zhao, Yuan Qing Wu, Min Wang, Donna M. Muzny, William E. Fisher, F. Charles Brunicardi, Sally E. Hodges, Jeffrey G. Reid, Jennifer Drummond, Kyle Chang, Yi Han, Lora R. Lewis, Huyen Dinh, Christian J. Buhay, Timothy Beck, Lee Timms, Michelle Sam, Kimberly Begley, Andrew Brown, Deepa Pai, Ami Panchal, Nicholas Buchner, Richard De Borja, Robert E. Denroche, Christina K. Yung, Stefano Serra, Nicole Onetto, Debabrata Mukhopadhyay, Ming-Sound Tsao, Patricia A. Shaw, Gloria M. Petersen, Steven Gallinger, Ralph H. Hruban, Anirban Maitra, Christine A. Iacobuzio-Donahue, Richard D. Schulick, Christopher L. Wolfgang, Richard A. Morgan, Rita T. Lawlor, Paola Capelli, Vincenzo Corbo, Maria Scardoni, Giampaolo Tortora, Margaret A. Tempero, Karen M. Mann, Nancy A. Jenkins, Pedro A. Perez-Mancera, David J. Adams, David A. Largaespada, Lodewyk F. A. Wessels, Alistair G. Rust, Lincoln D. Stein, David A. Tuveson, Neal G. Copeland, Elizabeth A. Musgrove, Aldo Scarpa, James R. Eshleman, Thomas J. Hudson, Robert L. Sutherland, David A. Wheeler, John V. Pearson, John D. McPherson, Richard A. Gibbs and Sean M. Grimmond

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody pp. 406-412

Jinghe Huang, Gilad Ofek, Leo Laub, Mark K. Louder, Nicole A. Doria-Rose, Nancy S. Longo, Hiromi Imamichi, Robert T. Bailer, Bimal Chakrabarti, Shailendra K. Sharma, S. Munir Alam, Tao Wang, Yongping Yang, Baoshan Zhang, Stephen A. Migueles, Richard Wyatt, Barton F. Haynes, Peter D. Kwong, John R. Mascola and Mark Connors

The Mu transpososome structure sheds light on DDE recombinase evolution pp. 413-417

Sherwin P. Montaño, Ying Z. Pigli and Phoebe A. Rice

A primordial origin for misalignments between stellar spin axes and planetary orbits pp. 418-420

Konstantin Batygin

Quantum-dot spin–photon entanglement via frequency downconversion to telecom wavelength pp. 421-425

Kristiaan De Greve, Leo Yu, Peter L. McMahon, Jason S. Pelc, Chandra M. Natarajan, Na Young Kim, Eisuke Abe, Sebastian Maier, Christian Schneider, Martin Kamp, Sven Höfling, Robert H. Hadfield, Alfred Forchel, M. M. Fejer and Yoshihisa Yamamoto

Observation of entanglement between a quantum dot spin and a single photon pp. 426-430

W. B. Gao, P. Fallahi, E. Togan, J. Miguel-Sanchez and A. Imamoglu

Spontaneous motion in hierarchically assembled active matter pp. 431-434

Tim Sanchez, Daniel T. N. Chen, Stephen J. DeCamp, Michael Heymann and Zvonimir Dogic

Little change in global drought over the past 60 years pp. 435-438

Justin Sheffield, Eric F. Wood and Michael L. Roderick

Slowdown of the Walker circulation driven by tropical Indo-Pacific warming pp. 439-443

Hiroki Tokinaga, Shang-Ping Xie, Clara Deser, Yu Kosaka and Yuko M. Okumura

The global diversity of birds in space and time pp. 444-448

W. Jetz, G. H. Thomas, J. B. Joy, K. Hartmann and A. O. Mooers

An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background pp. 449-453

Devarati Mitra, Xi Luo, Ann Morgan, Jin Wang, Mai P. Hoang, Jennifer Lo, Candace R. Guerrero, Jochen K. Lennerz, Martin C. Mihm, Jennifer A. Wargo, Kathleen C. Robinson, Suprabha P. Devi, Jillian C. Vanover, John A. D’Orazio, Martin McMahon, Marcus W. Bosenberg, Kevin M. Haigis, Daniel A. Haber, Yinsheng Wang and David E. Fisher

Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat pp. 454-457

Claudia Carrieri, Laura Cimatti, Marta Biagioli, Anne Beugnet, Silvia Zucchelli, Stefania Fedele, Elisa Pesce, Isidre Ferrer, Licio Collavin, Claudio Santoro, Alistair R. R. Forrest, Piero Carninci, Stefano Biffo, Elia Stupka and Stefano Gustincich

Serine is a natural ligand and allosteric activator of pyruvate kinase M2 pp. 458-462

Barbara Chaneton, Petra Hillmann, Liang Zheng, Agnès C. L. Martin, Oliver D. K. Maddocks, Achuthanunni Chokkathukalam, Joseph E. Coyle, Andris Jankevics, Finn P. Holding, Karen H. Vousden, Christian Frezza, Marc O’Reilly and Eyal Gottlieb

A vaccine strategy that protects against genital herpes by establishing local memory T cells pp. 463-467

Haina Shin and Akiko Iwasaki

A bimodular mechanism of calcium control in eukaryotes pp. 468-472

Henning Tidow, Lisbeth R. Poulsen, Antonina Andreeva, Michael Knudsen, Kim L. Hein, Carsten Wiuf, Michael G. Palmgren and Poul Nissen

Endothelial cell expression of haemoglobin α regulates nitric oxide signalling pp. 473-477

Adam C. Straub, Alexander W. Lohman, Marie Billaud, Scott R. Johnstone, Scott T. Dwyer, Monica Y. Lee, Pamela Schoppee Bortz, Angela K. Best, Linda Columbus, Benjamin Gaston and Brant E. Isakson

Structural insight into the type-II mitochondrial NADH dehydrogenases pp. 478-482

Yue Feng, Wenfei Li, Jian Li, Jiawei Wang, Jingpeng Ge, Duo Xu, Yanjing Liu, Kaiqi Wu, Qingyin Zeng, Jia-Wei Wu, Changlin Tian, Bing Zhou and Maojun Yang

Immigration: Waiting for green pp. 483-485

Karen Kaplan

Let slip the dogs pp. 488-488

William T. Vandemark

2012, volume 491, articles 7423

China’s new leaders must keep science in focus pp. 161-161

Peng Gong

Hurricane sweeps US into climate-adaptation debate pp. 167-168

Jeff Tollefson

Researchers battle storm’s wrath pp. 169-169

Brendan Borrell

Laser lab shifts focus to warheads pp. 170-171

Geoff Brumfiel

One-stop shop for disease genes pp. 171-171

Monya Baker

Space telescope to get software fix pp. 172-172

Ron Cowen

Irish science adviser office axed pp. 173-173

Declan Butler

Hopes linger for Mars methane pp. 174-174

Eric Hand

Education: Africa’s counting house pp. 176-178

Leigh Phillips

Melting in the Andes: Goodbye glaciers pp. 180-182

Barbara Fraser

The worm returns pp. 183-185

Joel V. Weinstock

The birth of X-ray crystallography pp. 186-187

John Meurig Thomas

Backyard jungles pp. 188-189

Stuart Pimm

Going massive pp. 190-190

Jonathan Butterworth

DNA dynamos pp. 191-191

Mark Haw

L'Aquila: governance flaws exposed pp. 192-192

Erik Aarden

L'Aquila: science is not a crystal ball pp. 192-192

Peter L. F. Fast

Rigid guidelines may restrict research pp. 192-192

Richard Morris

Call for a European integrity standard pp. 192-192

Alina Mungiu-Pippidi and Ligia Deca

Europe on the rise in Science and Nature pp. 192-192

Julio González-Alvarez

Keith H. Campbell (1954–2012) pp. 193-193

Alan Trounson

Mice and men show the way pp. 196-197

Evdokia Anagnostou

The fog clears pp. 197-198

Demetri Psaltis and Ioannis N. Papadopoulos

A glimpse of molecular competition pp. 198-200

Susan T. Lovett

Meet our closest neighbour pp. 200-201

Artie P. Hatzes

Bacterial power cords pp. 201-202

Gemma Reguera

Brighter images with no added noise pp. 202-203

Stéphane Clemmen and Alexander Gaeta

A toolbox for protein design pp. 204-205

Birte Höcker

Cosmic explosions in the young Universe pp. 205-206

Stephen J. Smartt

An Earth-mass planet orbiting α Centauri B pp. 207-211

Xavier Dumusque, Francesco Pepe, Christophe Lovis, Damien Ségransan, Johannes Sahlmann, Willy Benz, François Bouchy, Michel Mayor, Didier Queloz, Nuno Santos and Stéphane Udry

Input-specific control of reward and aversion in the ventral tegmental area pp. 212-217

Stephan Lammel, Byung Kook Lim, Chen Ran, Kee Wui Huang, Michael J. Betley, Kay M. Tye, Karl Deisseroth and Robert C. Malenka

Filamentous bacteria transport electrons over centimetre distances pp. 218-221

Christian Pfeffer, Steffen Larsen, Jie Song, Mingdong Dong, Flemming Besenbacher, Rikke Louise Meyer, Kasper Urup Kjeldsen, Lars Schreiber, Yuri A. Gorby, Mohamed Y. El-Naggar, Kar Man Leung, Andreas Schramm, Nils Risgaard-Petersen and Lars Peter Nielsen

Principles for designing ideal protein structures pp. 222-227

Nobuyasu Koga, Rie Tatsumi-Koga, Gaohua Liu, Rong Xiao, Thomas B. Acton, Gaetano T. Montelione and David Baker

Superluminous supernovae at redshifts of 2.05 and 3.90 pp. 228-231

Jeff Cooke, Mark Sullivan, Avishay Gal-Yam, Elizabeth J. Barton, Raymond G. Carlberg, Emma V. Ryan-Weber, Chuck Horst, Yuuki Omori and C. Gonzalo Díaz

Non-invasive imaging through opaque scattering layers pp. 232-234

Jacopo Bertolotti, Elbert G. van Putten, Christian Blum, Ad Lagendijk, Willem L. Vos and Allard P. Mosk

Integration of chemical catalysis with extractive fermentation to produce fuels pp. 235-239

Pazhamalai Anbarasan, Zachary C. Baer, Sanil Sreekumar, Elad Gross, Joseph B. Binder, Harvey W. Blanch, Douglas S. Clark and F. Dean Toste

Greenland ice-sheet contribution to sea-level rise buffered by meltwater storage in firn pp. 240-243

J. Harper, N. Humphrey, W. T. Pfeffer, J. Brown and X. Fettweis

Mechanisms for oscillatory true polar wander pp. 244-248

J. R. Creveling, J. X. Mitrovica, N.-H. Chan, K. Latychev and I. Matsuyama

Genetic programs constructed from layered logic gates in single cells pp. 249-253

Tae Seok Moon, Chunbo Lou, Alvin Tamsir, Brynne C. Stanton and Christopher A. Voigt

Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth pp. 254-258

Sergei I. Grivennikov, Kepeng Wang, Daniel Mucida, C. Andrew Stewart, Bernd Schnabl, Dominik Jauch, Koji Taniguchi, Guann-Yi Yu, Christoph H. Österreicher, Kenneth E. Hung, Christian Datz, Ying Feng, Eric R. Fearon, Mohamed Oukka, Lino Tessarollo, Vincenzo Coppola, Felix Yarovinsky, Hilde Cheroutre, Lars Eckmann, Giorgio Trinchieri and Michael Karin

IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine pp. 259-263

Samuel Huber, Nicola Gagliani, Lauren A. Zenewicz, Francis J. Huber, Lidia Bosurgi, Bo Hu, Matija Hedl, Wei Zhang, William O’Connor, Andrew J. Murphy, David M. Valenzuela, George D. Yancopoulos, Carmen J. Booth, Judy H. Cho, Wenjun Ouyang, Clara Abraham and Richard A. Flavell

Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions pp. 264-268

Ayumi Yoshizaki, Tomomitsu Miyagaki, David J. DiLillo, Takashi Matsushita, Mayuka Horikawa, Evgueni I. Kountikov, Rosanne Spolski, Jonathan C. Poe, Warren J. Leonard and Thomas F. Tedder

CaMKII determines mitochondrial stress responses in heart pp. 269-273

Mei-ling A. Joiner, Olha M. Koval, Jingdong Li, B. Julie He, Chantal Allamargot, Zhan Gao, Elizabeth D. Luczak, Duane D. Hall, Brian D. Fink, Biyi Chen, Jinying Yang, Steven A. Moore, Thomas D. Scholz, Stefan Strack, Peter J. Mohler, William I. Sivitz, Long-Sheng Song and Mark E. Anderson

Direct imaging of RecA nucleation and growth on single molecules of SSB-coated ssDNA pp. 274-278

Jason C. Bell, Jody L. Plank, Christopher C. Dombrowski and Stephen C. Kowalczykowski

The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis pp. 279-283

Jonathan J. Ipsaro, Astrid D. Haase, Simon R. Knott, Leemor Joshua-Tor and Gregory J. Hannon

Structure and function of Zucchini endoribonuclease in piRNA biogenesis pp. 284-287

Hiroshi Nishimasu, Hirotsugu Ishizu, Kuniaki Saito, Satoshi Fukuhara, Miharu K. Kamatani, Luc Bonnefond, Naoki Matsumoto, Tomohiro Nishizawa, Keita Nakanaga, Junken Aoki, Ryuichiro Ishitani, Haruhiko Siomi, Mikiko C. Siomi and Osamu Nureki

Correction: Corrigendum: Reconstructing Native American population history pp. 288-288

David Reich, Nick Patterson, Desmond Campbell, Arti Tandon, Stéphane Mazieres, Nicolas Ray, Maria V. Parra, Winston Rojas, Constanza Duque, Natalia Mesa, Luis F. García, Omar Triana, Silvia Blair, Amanda Maestre, Juan C. Dib, Claudio M. Bravi, Graciela Bailliet, Daniel Corach, Tábita Hünemeier, Maria Cátira Bortolini, Francisco M. Salzano, María Luiza Petzl-Erler, Victor Acuña-Alonzo, Carlos Aguilar-Salinas, Samuel Canizales-Quinteros, Teresa Tusié-Luna, Laura Riba, Maricela Rodríguez-Cruz, Mardia Lopez-Alarcón, Ramón Coral-Vazquez, Thelma Canto-Cetina, Irma Silva-Zolezzi, Juan Carlos Fernandez-Lopez, Alejandra V. Contreras, Gerardo Jimenez-Sanchez, Maria José Gómez-Vázquez, Julio Molina, Ángel Carracedo, Antonio Salas, Carla Gallo, Giovanni Poletti, David B.Witonsky, Gorka Alkorta-Aranburu, Rem I. Sukernik, Ludmila Osipova, Sardana A. Fedorova, René Vasquez, Mercedes Villena, Claudia Moreau, Ramiro Barrantes, David Pauls, Laurent Excoffier, Gabriel Bedoya, Francisco Rothhammer, Jean-Michel Dugoujon, Georges Larrouy, William Klitz, Damian Labuda, Judith Kidd, Kenneth Kidd, Anna Di Rienzo, Nelson B. Freimer, Alkes L. Price and Andrés Ruiz-Linares

Biomedical research: Texas potential pp. 289-290

Laura Beil

Turning point: Olivier Guyon pp. 291-291

Virginia Gewin

The candidate pool pp. 294-294

Brian Hurrel and Jeff Samson

2012, volume 491, articles 7422

Autism pp. S1-S1

Herb Brody

Epidemiology: Complex disorder pp. S2-S3

Virginia Hughes

Genetics: Searching for answers pp. S4-S6

Sarah C. P. Williams

Child development: The first steps pp. S7-S9

Katherine Bourzac

How women scientists fare in the Arab world pp. 9-9

Rana Dajani

Adulthood: Life lessons pp. S10-S11

Lindsay Borthwick

Diagnosis: Redefining autism pp. S12-S13

Emily Singer

Treatments: In the waiting room pp. S14-S16

Michael Eisenstein

L’Aquila verdict row grows pp. 15-16

Nicola Nosengo

Sahara solar plan loses its shine pp. 16-17

Devin Powell

Perspective: Imaging autism pp. S17-S17

Nicholas Lange

Culture: Diverse diagnostics pp. S18-S19

Sarah DeWeerdt

NIH faces chimp housing quandary pp. 18-18

Meredith Wadman

Theorists bridge space-time rips pp. 19-19

Eugenie Samuel Reich

Perspective: Brain scans need a rethink pp. S20-S20

Ben Deen and Kevin Pelphrey

Hepatitis E vaccine debuts pp. 21-22

Soo Bin Park

Bid to curb fried-food chemical goes cold pp. 22-23

Katharine Sanderson

Science in the developing world: Eritrea's shattered science pp. 24-26

Shanta Barley

Genomics: The single life pp. 27-29

Brian Owens

There's more to life than rats and flies pp. 31-33

Jessica Bolker

Politics and fetal diagnostics collide pp. 33-34

Jaime S. King

Base sustainable development goals on science pp. 35-35

Gisbert Glaser

Neuroscience: Found in translation pp. 36-37

Charles Fernyhough

History: Realms of gold pp. 38-38

Jennifer Rampling

Geography: Going all the way pp. 39-39

Andrew Robinson

Handful of papers dominates citation pp. 40-40

Albert-László Barabási, Chaoming Song and Dashun Wang

Call to register new species in ZooBank pp. 40-40

Gary Rosenberg, Frank-T. Krell and Richard Pyle

Problems enforcing Ecuador ecology law pp. 40-40

Kelly Swing and Luis Sempértegui

Open collaboration is key to new drugs pp. 40-40

Markus Gruetter

Self-assembly gets new direction pp. 42-43

Matthew R. Jones and Chad A. Mirkin

Bumblebees and pesticides pp. 43-45

Juliet L. Osborne

Dark and stormy weather pp. 45-46

Beth Ellen Clark

Sleep to oblivion pp. 46-46

Sadaf Shadan

Nanotube holograms pp. 47-48

Stéphane Larouche and David R. Smith

The cooperative gene pp. 48-49

James Attwater and Philipp Holliger

Colloids with valence and specific directional bonding pp. 51-55

Yufeng Wang, Yu Wang, Dana R. Breed, Vinothan N. Manoharan, Lang Feng, Andrew D. Hollingsworth, Marcus Weck and David J. Pine

Generation of functional thyroid from embryonic stem cells pp. 66-71

Francesco Antonica, Dominika Figini Kasprzyk, Robert Opitz, Michelina Iacovino, Xiao-Hui Liao, Alexandra Mihaela Dumitrescu, Samuel Refetoff, Kathelijne Peremans, Mario Manto, Michael Kyba and Sabine Costagliola

Spontaneous network formation among cooperative RNA replicators pp. 72-77

Nilesh Vaidya, Michael L. Manapat, Irene A. Chen, Ramon Xulvi-Brunet, Eric J. Hayden and Niles Lehman

Distinctive space weathering on Vesta from regolith mixing processes pp. 79-82

C. M. Pieters, E. Ammannito, D. T. Blewett, B. W. Denevi, M. C. De Sanctis, M. J. Gaffey, L. Le Corre, J.-Y. Li, S. Marchi, T. B. McCord, L. A. McFadden, D. W. Mittlefehldt, A. Nathues, E. Palmer, V. Reddy, C. A. Raymond and C. T. Russell

Dark material on Vesta from the infall of carbonaceous volatile-rich material pp. 83-86

T. B. McCord, J.-Y. Li, J.-P. Combe, H. Y. McSween, R. Jaumann, V. Reddy, F. Tosi, D. A. Williams, D. T. Blewett, D. Turrini, E. Palomba, C. M. Pieters, M. C. De Sanctis, E. Ammannito, M. T. Capria, L. Le Corre, A. Longobardo, A. Nathues, D. W. Mittlefehldt, S. E. Schröder, H. Hiesinger, A. W. Beck, F. Capaccioni, U. Carsenty, H. U. Keller, B. W. Denevi, J. M. Sunshine, C. A. Raymond and C. T. Russell

Observation of spatially ordered structures in a two-dimensional Rydberg gas pp. 87-91

Peter Schauß, Marc Cheneau, Manuel Endres, Takeshi Fukuhara, Sebastian Hild, Ahmed Omran, Thomas Pohl, Christian Gross, Stefan Kuhr and Immanuel Bloch

Fluvial response to abrupt global warming at the Palaeocene/Eocene boundary pp. 92-95

Brady Z. Foreman, Paul L. Heller and Mark T. Clementz

The elusive Hadean enriched reservoir revealed by 142Nd deficits in Isua Archaean rocks pp. 96-100

Hanika Rizo, Maud Boyet, Janne Blichert-Toft, Jonathan O’Neil, Minik T. Rosing and Jean-Louis Paquette

Fault healing promotes high-frequency earthquakes in laboratory experiments and on natural faults pp. 101-104

Gregory C. McLaskey, Amanda M. Thomas, Steven D. Glaser and Robert M. Nadeau

Combined pesticide exposure severely affects individual- and colony-level traits in bees pp. 105-108

Richard J. Gill, Oscar Ramos-Rodriguez and Nigel E. Raine

Intrinsically determined cell death of developing cortical interneurons pp. 109-113

Derek G. Southwell, Mercedes F. Paredes, Rui P. Galvao, Daniel L. Jones, Robert C. Froemke, Joy Y. Sebe, Clara Alfaro-Cervello, Yunshuo Tang, Jose M. Garcia-Verdugo, John L. Rubenstein, Scott C. Baraban and Arturo Alvarez-Buylla

In vivo genome editing using a high-efficiency TALEN system pp. 114-118

Victoria M. Bedell, Ying Wang, Jarryd M. Campbell, Tanya L. Poshusta, Colby G. Starker, Randall G. Krug, Wenfang Tan, Sumedha G. Penheiter, Alvin C. Ma, Anskar Y. H. Leung, Scott C. Fahrenkrug, Daniel F. Carlson, Daniel F. Voytas, Karl J. Clark, Jeffrey J. Essner and Stephen C. Ekker

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease pp. 119-124

Luke Jostins, Stephan Ripke, Rinse K. Weersma, Richard H. Duerr, Dermot P. McGovern, Ken Y. Hui, James C. Lee, L. Philip Schumm, Yashoda Sharma, Carl A. Anderson, Jonah Essers, Mitja Mitrovic, Kaida Ning, Isabelle Cleynen, Emilie Theatre, Sarah L. Spain, Soumya Raychaudhuri, Philippe Goyette, Zhi Wei, Clara Abraham, Jean-Paul Achkar, Tariq Ahmad, Leila Amininejad, Ashwin N. Ananthakrishnan, Vibeke Andersen, Jane M. Andrews, Leonard Baidoo, Tobias Balschun, Peter A. Bampton, Alain Bitton, Gabrielle Boucher, Stephan Brand, Carsten Büning, Ariella Cohain, Sven Cichon, Mauro D’Amato, Dirk De Jong, Kathy L. Devaney, Marla Dubinsky, Cathryn Edwards, David Ellinghaus, Lynnette R. Ferguson, Denis Franchimont, Karin Fransen, Richard Gearry, Michel Georges, Christian Gieger, Jürgen Glas, Talin Haritunians, Ailsa Hart, Chris Hawkey, Matija Hedl, Xinli Hu, Tom H. Karlsen, Limas Kupcinskas, Subra Kugathasan, Anna Latiano, Debby Laukens, Ian C. Lawrance, Charlie W. Lees, Edouard Louis, Gillian Mahy, John Mansfield, Angharad R. Morgan, Craig Mowat, William Newman, Orazio Palmieri, Cyriel Y. Ponsioen, Uros Potocnik, Natalie J. Prescott, Miguel Regueiro, Jerome I. Rotter, Richard K. Russell, Jeremy D. Sanderson, Miquel Sans, Jack Satsangi, Stefan Schreiber, Lisa A. Simms, Jurgita Sventoraityte, Stephan R. Targan, Kent D. Taylor, Mark Tremelling, Hein W. Verspaget, Martine De Vos, Cisca Wijmenga, David C. Wilson, Juliane Winkelmann, Ramnik J. Xavier, Sebastian Zeissig, Bin Zhang, Clarence K. Zhang, Hongyu Zhao, Mark S. Silverberg, Vito Annese, Hakon Hakonarson, Steven R. Brant, Graham Radford-Smith, Christopher G. Mathew, John D. Rioux, Eric E. Schadt, Mark J. Daly, Andre Franke, Miles Parkes, Severine Vermeire, Jeffrey C. Barrett and Judy H Cho

Codon-usage-based inhibition of HIV protein synthesis by human schlafen 11 pp. 125-128

Manqing Li, Elaine Kao, Xia Gao, Hilary Sandig, Kirsten Limmer, Mariana Pavon-Eternod, Thomas E. Jones, Sebastien Landry, Tao Pan, Matthew D. Weitzman and Michael David

Vaccine-induced CD8+ T cells control AIDS virus replication pp. 129-133

Philip A. Mudd, Mauricio A. Martins, Adam J. Ericsen, Damien C. Tully, Karen A. Power, Alex T. Bean, Shari M. Piaskowski, Lijie Duan, Aaron Seese, Adrianne D. Gladden, Kim L. Weisgrau, Jessica R. Furlott, Young-il Kim, Marlon G. Veloso de Santana, Eva Rakasz, Saverio Capuano, Nancy A. Wilson, Myrna C. Bonaldo, Ricardo Galler, David B. Allison, Michael Piatak, Ashley T. Haase, Jeffrey D. Lifson, Todd M. Allen and David I. Watkins

The molecular basis of phosphate discrimination in arsenate-rich environments pp. 134-137

Mikael Elias, Alon Wellner, Korina Goldin-Azulay, Eric Chabriere, Julia A. Vorholt, Tobias J. Erb and Dan S. Tawfik

The spatial architecture of protein function and adaptation pp. 138-142

Richard N. McLaughlin, Frank J. Poelwijk, Arjun Raman, Walraj S. Gosal and Rama Ranganathan

Reading the second genomic code pp. 143-147

Vivien Marx

Food science: A smorgasbord of opportunity pp. 149-150

Alla Katsnelson

Career fast-forward pp. 151-151

Katharina Genreith

Midnight in the cathedral of time pp. 154-154

Preston Grassmann