Cellular memory erased in human embryos

Wolf Reik and Gavin Kelsey
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Wolf Reik: Wolf Reik and Gavin Kelsey are in the Epigenetics Programme, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK, and at the Centre for Trophoblast Research, University of Cambridge.
Gavin Kelsey: Wolf Reik and Gavin Kelsey are in the Epigenetics Programme, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK, and at the Centre for Trophoblast Research, University of Cambridge.

Nature, 2014, vol. 511, issue 7511, 540-541

Abstract: Two analyses of human eggs, sperm and early-stage embryos reveal a pronounced loss of DNA methylation — a molecular modification that affects gene transcription — after fertilization. See Letters p.606 & p.611

Date: 2014
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DOI: 10.1038/nature13648

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