Germline variant FGFR4 p.G388R exposes a membrane-proximal STAT3 binding site

Vijay K. Ulaganathan (), Bianca Sperl, Ulf R. Rapp and Axel Ullrich ()
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Vijay K. Ulaganathan: Max Planck Institute for Biochemistry
Bianca Sperl: Max Planck Institute for Biochemistry
Ulf R. Rapp: Max Planck Institute for Heart and Lung Research, Molecular Mechanisms of Lung Cancer
Axel Ullrich: Max Planck Institute for Biochemistry

Nature, 2015, vol. 528, issue 7583, 570-574

Abstract: A gain-of-function effect of the cancer-associated rs351855 single-nucleotide polymorphism encoding the FGFR4 Arg388 allele in humans.

Date: 2015
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DOI: 10.1038/nature16449

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