Polarized endosome dynamics by spindle asymmetry during asymmetric cell division

Emmanuel Derivery (), Carole Seum, Alicia Daeden, Sylvain Loubéry, Laurent Holtzer, Frank Jülicher () and Marcos Gonzalez-Gaitan ()
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Emmanuel Derivery: Faculty of Sciences, University of Geneva
Carole Seum: Faculty of Sciences, University of Geneva
Alicia Daeden: Faculty of Sciences, University of Geneva
Sylvain Loubéry: Faculty of Sciences, University of Geneva
Laurent Holtzer: Faculty of Sciences, University of Geneva
Frank Jülicher: Max Planck Institute for the Physics of Complex Systems
Marcos Gonzalez-Gaitan: Faculty of Sciences, University of Geneva

Nature, 2015, vol. 528, issue 7581, 280-285

Abstract: Central spindle asymmetry, generated by the kinesin Klp10A and its antagonist Patronin, polarizes endosome motility and provides a mechanism for the asymmetric segregation of signalling endosomes observed in a variety of asymmetrically dividing cell types.

Date: 2015
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DOI: 10.1038/nature16443

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