Visualization of splenic marginal zone B-cell shuttling and follicular B-cell egress

Tal I. Arnon, Robert M. Horton, Irina L. Grigorova and Jason G. Cyster ()
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Tal I. Arnon: University of California
Robert M. Horton: University of California
Irina L. Grigorova: University of California
Jason G. Cyster: University of California

Nature, 2013, vol. 493, issue 7434, 684-688

Abstract: Lymphocyte migration in the spleen is visualized live in mice using a real-time two-photon laser-scanning microscopy approach revealing that marginal zone and follicular B cells are highly motile and can shuttle between compartments, and integrin adhesion is the key to cellular retention in the marginal zone.

Date: 2013
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DOI: 10.1038/nature11738

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