Accelerated growth in the absence of DNA replication origins

Michelle Hawkins, Sunir Malla, Martin J. Blythe, Conrad A. Nieduszynski () and Thorsten Allers ()
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Michelle Hawkins: School of Biology, University of Nottingham, Queen’s Medical Centre, Nottingham NG7 2UH, UK
Sunir Malla: Deep Seq, University of Nottingham, Queen’s Medical Centre, Nottingham NG7 2UH, UK
Martin J. Blythe: Deep Seq, University of Nottingham, Queen’s Medical Centre, Nottingham NG7 2UH, UK
Conrad A. Nieduszynski: School of Biology, University of Nottingham, Queen’s Medical Centre, Nottingham NG7 2UH, UK
Thorsten Allers: School of Biology, University of Nottingham, Queen’s Medical Centre, Nottingham NG7 2UH, UK

Nature, 2013, vol. 503, issue 7477, 544-547

Abstract: When all origins of replication are deleted from the archaeon Haloferax volcanii, homologous recombination is used to initiate DNA replication and the growth rate is accelerated.

Date: 2013
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DOI: 10.1038/nature12650

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