A cross-chiral RNA polymerase ribozyme

Jonathan T. Sczepanski and Gerald F. Joyce ()
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Jonathan T. Sczepanski: The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA
Gerald F. Joyce: The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA

Nature, 2014, vol. 515, issue 7527, 440-442

Abstract: Here, a cross-chiral RNA polymerase is developed—an RNA enzyme that can catalyse the templated polymerization of activated mononucleotides that are of the opposite handedness—shedding light on how RNA-based life could have emerged.

Date: 2014
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DOI: 10.1038/nature13900

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