Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells

Thomas M. Carlile, Maria F. Rojas-Duran, Boris Zinshteyn, Hakyung Shin, Kristen M. Bartoli and Wendy V. Gilbert ()
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Thomas M. Carlile: Massachusetts Institute of Technology
Maria F. Rojas-Duran: Massachusetts Institute of Technology
Boris Zinshteyn: Massachusetts Institute of Technology
Hakyung Shin: Massachusetts Institute of Technology
Kristen M. Bartoli: Massachusetts Institute of Technology
Wendy V. Gilbert: Massachusetts Institute of Technology

Nature, 2014, vol. 515, issue 7525, 143-146

Abstract: The modification of uridine to pseudouridine is widespread in transfer and ribosomal RNAs but not observed so far in a coding RNA; here a new technique is used to detect this modification on a genome-wide scale, leading to the identification of pseudouridylation in messenger RNAs as well as almost 100 new sites in non-coding RNAs.

Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:515:y:2014:i:7525:d:10.1038_nature13802

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DOI: 10.1038/nature13802

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