Nodal signalling determines biradial asymmetry in Hydra

Hiroshi Watanabe (), Heiko A. Schmidt, Anne Kuhn, Stefanie K. Höger, Yigit Kocagöz, Nico Laumann-Lipp, Suat Özbek and Thomas W. Holstein ()
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Hiroshi Watanabe: Centre for Organismal Studies (COS), Heidelberg University, 69120 Heidelberg, Germany
Heiko A. Schmidt: Center for Integrative Bioinformatics Vienna (CIBIV), Max F. Perutz Laboratories (MFPL), University of Vienna/Medical University of Vienna, 1030 Vienna, Austria
Anne Kuhn: Centre for Organismal Studies (COS), Heidelberg University, 69120 Heidelberg, Germany
Stefanie K. Höger: Centre for Organismal Studies (COS), Heidelberg University, 69120 Heidelberg, Germany
Yigit Kocagöz: Centre for Organismal Studies (COS), Heidelberg University, 69120 Heidelberg, Germany
Nico Laumann-Lipp: Centre for Organismal Studies (COS), Heidelberg University, 69120 Heidelberg, Germany
Suat Özbek: Centre for Organismal Studies (COS), Heidelberg University, 69120 Heidelberg, Germany
Thomas W. Holstein: Centre for Organismal Studies (COS), Heidelberg University, 69120 Heidelberg, Germany

Nature, 2014, vol. 515, issue 7525, 112-115

Abstract: A Nodal-related gene is uncovered in Hydra and is involved in setting up the body axis, and a β-Catenin–Nodal–Pitx signalling cassette is shown to have existed before the divergence of cnidarians, including Hydra, and bilaterians.

Date: 2014
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DOI: 10.1038/nature13666

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