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piRNA-mediated regulation of transposon alternative splicing in the soma and germ line

Felipe Karam Teixeira (), Martyna Okuniewska, Colin D. Malone, Rémi-Xavier Coux, Donald C. Rio and Ruth Lehmann ()
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Felipe Karam Teixeira: Howard Hughes Medical Institute (HHMI) and Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine
Martyna Okuniewska: Howard Hughes Medical Institute (HHMI) and Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine
Colin D. Malone: Howard Hughes Medical Institute (HHMI) and Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine
Rémi-Xavier Coux: Howard Hughes Medical Institute (HHMI) and Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine
Donald C. Rio: Center for RNA Systems Biology, and California Institute for Quantitative Biosciences, University of California
Ruth Lehmann: Howard Hughes Medical Institute (HHMI) and Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine

Nature, 2017, vol. 552, issue 7684, 268-272

Abstract: A new mechanism of pre-mRNA splicing regulation is revealed that is mediated by piRNA pathway components and is dependent on heterochromatin histone modifications.

Date: 2017
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DOI: 10.1038/nature25018

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