Genetically programmed chiral organoborane synthesis

S. B. Jennifer Kan, Xiongyi Huang, Yosephine Gumulya, Kai Chen and Frances H. Arnold ()
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S. B. Jennifer Kan: California Institute of Technology, 1200 East California Boulevard
Xiongyi Huang: California Institute of Technology, 1200 East California Boulevard
Yosephine Gumulya: California Institute of Technology, 1200 East California Boulevard
Kai Chen: California Institute of Technology, 1200 East California Boulevard
Frances H. Arnold: California Institute of Technology, 1200 East California Boulevard

Nature, 2017, vol. 552, issue 7683, 132-136

Abstract: A genetically encoded platform can produce chiral organoboranes in bacteria with high turnover, enantioselectivity and chemoselectivity, and can be tuned and configured through DNA manipulation.

Date: 2017
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DOI: 10.1038/nature24996

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