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Optimal reactive vaccination strategies for a foot-and-mouth outbreak in the UK

Michael J. Tildesley, Nicholas J. Savill, Darren J. Shaw, Rob Deardon, Stephen P. Brooks, Mark E. J. Woolhouse, Bryan T. Grenfell and Matt J. Keeling ()
Additional contact information
Michael J. Tildesley: University of Warwick
Nicholas J. Savill: University of Cambridge
Darren J. Shaw: University of Edinburgh, Easter Bush Veterinary Centre
Rob Deardon: University of Cambridge
Stephen P. Brooks: University of Cambridge
Mark E. J. Woolhouse: University of Edinburgh, Ashworth Laboratories
Bryan T. Grenfell: Pennsylvania State University
Matt J. Keeling: University of Warwick

Nature, 2006, vol. 440, issue 7080, 83-86

Abstract: Vaccination next time? Vaccination didn't feature among the controls used in the United Kingdom during the foot-and-mouth disease epidemic of 2001. New Europe-wide policies, however, mean that next time, or when a similar disease threatens, reactive vaccination may be a preferred means of control. Data from the 2001 outbreak have now been used in an epidemiological model to work out the most efficient way of deploying vaccine stocks to restrict an outbreak by ring vaccination. Optimum containment is achieved by ignoring the order in which infections are reported, and instead vaccinating on the farms closest to previously reported cases.

Date: 2006
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Citations: View citations in EconPapers (14)

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DOI: 10.1038/nature04324

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