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Chromatin unbound

Jan Vijg () and Yousin Suh ()
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Jan Vijg: the Buck Institute for Age Research
Yousin Suh: University of Texas Health Science Center

Nature, 2006, vol. 440, issue 7086, 874-875

Abstract: Sir2 proteins slow ageing in yeast by locking chromatin — the DNA and proteins in chromosomes — into a stable, silent state. Inactivating a Sir2 family protein in mice causes premature ageing and genome instability.

Date: 2006
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DOI: 10.1038/440874a

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