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Capturing pairwise and multi-way chromosomal conformations using chromosomal walks

Pedro Olivares-Chauvet, Zohar Mukamel, Aviezer Lifshitz, Omer Schwartzman, Noa Oded Elkayam, Yaniv Lubling, Gintaras Deikus, Robert P. Sebra and Amos Tanay ()
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Pedro Olivares-Chauvet: Weizmann Institute
Zohar Mukamel: Weizmann Institute
Aviezer Lifshitz: Weizmann Institute
Omer Schwartzman: Weizmann Institute
Noa Oded Elkayam: Weizmann Institute
Yaniv Lubling: Weizmann Institute
Gintaras Deikus: Icahn Institute and Dept. of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai
Robert P. Sebra: Icahn Institute and Dept. of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai
Amos Tanay: Weizmann Institute

Nature, 2016, vol. 540, issue 7632, 296-300

Abstract: A conformation capture sequencing method is developed to link multiple genomic loci into three-dimensional proximity chains called chromosomal walks (C-walks), adding to our understanding of how higher-order chromosomal structures participate in genome regulation.

Date: 2016
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DOI: 10.1038/nature20158

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