A call for transparent reporting to optimize the predictive value of preclinical research

Story C. Landis, Susan G. Amara, Khusru Asadullah, Chris P. Austin, Robi Blumenstein, Eileen W. Bradley, Ronald G. Crystal, Robert B. Darnell, Robert J. Ferrante, Howard Fillit, Robert Finkelstein, Marc Fisher, Howard E. Gendelman, Robert M. Golub, John L. Goudreau, Robert A. Gross, Amelie K. Gubitz, Sharon E. Hesterlee, David W. Howells, John Huguenard, Katrina Kelner, Walter Koroshetz, Dimitri Krainc, Stanley E. Lazic, Michael S. Levine, Malcolm R. Macleod, John M. McCall, Richard T. Moxley, Kalyani Narasimhan, Linda J. Noble, Steve Perrin, John D. Porter, Oswald Steward, Ellis Unger, Ursula Utz and Shai D. Silberberg ()
Additional contact information
Story C. Landis: National Institute of Neurological Disorders and Stroke, NIH
Susan G. Amara: University of Pittsburgh School of Medicine
Khusru Asadullah: Bayer HealthCare
Chris P. Austin: National Center for Advancing Translational Sciences, NIH
Robi Blumenstein: CHDI Management/CHDI Foundation
Eileen W. Bradley: Center for Review, NIH, Bethesda, Maryland 20892, USA
Ronald G. Crystal: Weill Cornell Medical College
Robert B. Darnell: Howard Hughes Medical Institute, The Rockefeller University
Robert J. Ferrante: University of Pittsburgh
Howard Fillit: Alzheimer's Drug Discovery Foundation
Robert Finkelstein: National Institute of Neurological Disorders and Stroke, NIH
Marc Fisher: University of Massachusetts Medical School
Howard E. Gendelman: University of Nebraska Medical Center
Robert M. Golub: JAMA
John L. Goudreau: Michigan State University
Robert A. Gross: University of Rochester Medical Center
Amelie K. Gubitz: National Institute of Neurological Disorders and Stroke, NIH
Sharon E. Hesterlee: Parent Project Muscular Dystrophy
David W. Howells: The Florey Institute of Neuroscience and Mental Health, University of Melbourne
John Huguenard: Neurology and Neurological Sciences and Cellular and Molecular Physiology, Stanford University
Katrina Kelner: Science Translational Medicine, AAAS, Washington DC 22201, USA
Walter Koroshetz: National Institute of Neurological Disorders and Stroke, NIH
Dimitri Krainc: Harvard Medical School, Massachusetts General Hospital
Stanley E. Lazic: F. Hoffmann-La Roche
Michael S. Levine: University of California Los Angeles
Malcolm R. Macleod: University of Edinburgh, Western General Hospital
John M. McCall: PharMac LLC
Richard T. Moxley: University of Rochester Medical Center, School of Medicine and Dentistry
Kalyani Narasimhan: Nature Neuroscience
Linda J. Noble: University of California San Francisco
Steve Perrin: ALS Therapy Development Institute
John D. Porter: National Institute of Neurological Disorders and Stroke, NIH
Oswald Steward: Reeve-Irvine Research Center, University of California Irvine
Ellis Unger: Office of New Drugs, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland 20993, USA
Ursula Utz: National Institute of Neurological Disorders and Stroke, NIH
Shai D. Silberberg: National Institute of Neurological Disorders and Stroke, NIH

Nature, 2012, vol. 490, issue 7419, 187-191

Abstract: Deficiencies in methods reporting in animal experimentation lead to difficulties in reproducing experiments; the authors propose a set of reporting standards to improve scientific communication and study design.

Date: 2012
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DOI: 10.1038/nature11556

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